SYNE4

Summary

Gene Symbol: SYNE4
Description: spectrin repeat containing nuclear envelope family member 4
Alias: C19orf46, DFNB76, KASH4, Nesp4, nesprin-4, KASH domain-containing protein 4, deafness, autosomal recessive 76, nuclear envelope spectrin repeat protein 4
Species: human
Products:     SYNE4

Top Publications

  1. Roux K, Crisp M, Liu Q, Kim D, Kozlov S, Stewart C, et al. Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization. Proc Natl Acad Sci U S A. 2009;106:2194-9 pubmed publisher
    ..A search for proteins displaying a conserved C-terminal sequence present in nesprins 1-3 identified nesprin 4 (Nesp4), a new member of this family...
  2. Horn H, Brownstein Z, Lenz D, Shivatzki S, Dror A, Dagan Rosenfeld O, et al. The LINC complex is essential for hearing. J Clin Invest. 2013;123:740-50 pubmed publisher
    ..hearing loss in 2 families of Iraqi Jewish ancestry was due to homozygosity for the protein truncating mutation SYNE4 c.228delAT...