STIP1

Summary

Gene Symbol: STIP1
Description: stress induced phosphoprotein 1
Alias: HEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L, stress-induced-phosphoprotein 1, Hsp70/Hsp90-organizing protein, NY-REN-11 antigen, epididymis secretory sperm binding protein Li 94n, hsc70/Hsp90-organizing protein, renal carcinoma antigen NY-REN-11, transformation-sensitive protein IEF SSP 3521
Species: human
Products:     STIP1

Top Publications

  1. Johnson B, Schumacher R, Ross E, Toft D. Hop modulates Hsp70/Hsp90 interactions in protein folding. J Biol Chem. 1998;273:3679-86 pubmed
    ..Similar stimulation was observed when Hop was replaced by its yeast homolog Sti1. In assays of the binding of Hop to hsp70 and hsp90, Hop preferentially forms a complex with ADP-bound hsp70, and ..
  2. Longshaw V, Chapple J, Balda M, Cheetham M, Blatch G. Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases. J Cell Sci. 2004;117:701-10 pubmed
    The co-chaperone murine stress-inducible protein 1 (mSTI1), an Hsp70/Hsp90 organizing protein (Hop) homologue, mediates the assembly of the Hsp70/Hsp90 chaperone heterocomplex...
  3. Scheufler C, Brinker A, Bourenkov G, Pegoraro S, Moroder L, Bartunik H, et al. Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell. 2000;101:199-210 pubmed
    The adaptor protein Hop mediates the association of the molecular chaperones Hsp70 and Hsp90...
  4. Yi F, Doudevski I, Regan L. HOP is a monomer: investigation of the oligomeric state of the co-chaperone HOP. Protein Sci. 2010;19:19-25 pubmed publisher
    The co-chaperone Hsp70-Hsp90 organizing protein (HOP) plays a central role in protein folding in vivo, binding to both Hsp70 and Hsp90 and bringing them together in a functional complex...
  5. Skalnikova H, Martinkova J, Hrabakova R, Halada P, Dziechciarkova M, Hajduch M, et al. Cancer drug-resistance and a look at specific proteins: Rho GDP-dissociation inhibitor 2, Y-box binding protein 1, and HSP70/90 organizing protein in proteomics clinical application. J Proteome Res. 2011;10:404-15 pubmed publisher
    ..Furthermore, these proteins were validated for their roles in drug resistance using different cell lines resistant to diverse representatives of anti-cancer drugs such as vincristine and daunorubicin. ..
  6. Donnelly B, Needham P, Snyder A, Roy A, Khadem S, Brodsky J, et al. Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis. J Biol Chem. 2013;288:13124-35 pubmed publisher
    ..Collectively, these observations indicate that Hsp70 and Hsp90 comprise two functionally distinct ER quality control checkpoints that sequentially monitor NCC biogenesis...
  7. Brinker A, Scheufler C, Von Der Mulbe F, Fleckenstein B, Herrmann C, Jung G, et al. Ligand discrimination by TPR domains. Relevance and selectivity of EEVD-recognition in Hsp70 x Hop x Hsp90 complexes. J Biol Chem. 2002;277:19265-75 pubmed
    ..The TPR1 and TPR2A domains of the Hsp70/Hsp90 adapter protein p60/Hop specifically bind to short peptides corresponding to the C-terminal tails of Hsp70 and Hsp90, respectively, both of ..
  8. Zanata S, Lopes M, Mercadante A, Hajj G, Chiarini L, Nomizo R, et al. Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J. 2002;21:3307-16 pubmed
    ..gels followed by sequencing the specific spot, we have now identified the molecule as stress-inducible protein 1 (STI1). We show that this protein is also found at the cell membrane besides the cytoplasm...
  9. Onuoha S, Coulstock E, Grossmann J, Jackson S. Structural studies on the co-chaperone Hop and its complexes with Hsp90. J Mol Biol. 2008;379:732-44 pubmed publisher
    The tetratricopeptide repeat domain (TPR)-containing co-chaperone Hsp-organising protein (Hop) plays a critical role in mediating interactions between Heat Shock Protein (Hsp)70 and Hsp90 as part of the cellular assembly machine...

More Information

Publications126 found, 100 shown here

  1. Carrigan P, Riggs D, Chinkers M, Smith D. Functional comparison of human and Drosophila Hop reveals novel role in steroid receptor maturation. J Biol Chem. 2005;280:8906-11 pubmed
    Hsp70/Hsp90 organizing protein (Hop) coordinates Hsp70 and Hsp90 interactions during assembly of steroid receptor complexes...
  2. Kundrat L, Regan L. Balance between folding and degradation for Hsp90-dependent client proteins: a key role for CHIP. Biochemistry. 2010;49:7428-38 pubmed publisher
    ..The central players are the molecular chaperones Hsp70 and Hsp90, the cochaperone HOP, and ubiquitin ligase, CHIP...
  3. Li J, Richter K, Buchner J. Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle. Nat Struct Mol Biol. 2011;18:61-6 pubmed publisher
    ..The first cochaperone entering the cycle is the Hsp90 ATPase inhibitor Sti1 (Hop in human), which later is replaced by a prolyl isomerase (PPIase) and p23...
  4. Walsh N, Larkin A, Swan N, Conlon K, Dowling P, McDermott R, et al. RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation. Cancer Lett. 2011;306:180-9 pubmed publisher
    We previously identified Hop as over expressed in invasive pancreatic cancer cell lines and malignant tissues of pancreatic cancer patients, suggesting an important role for Hop in the biology of invasive pancreatic cancer...
  5. Tsai C, Tsai C, Lin C, Chen H, Lee Y, Chao A, et al. Secreted stress-induced phosphoprotein 1 activates the ALK2-SMAD signaling pathways and promotes cell proliferation of ovarian cancer cells. Cell Rep. 2012;2:283-93 pubmed publisher
    Stress-induced phosphoprotein 1 (STIP1), a cochaperone that organizes other chaperones, heat shock proteins (HSPs), was recently shown to be secreted by human ovarian cancer cells...
  6. Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi M, Ferrari V, et al. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. Autophagy. 2019;15:631-651 pubmed publisher
    ..cells; SOD1: superoxide dismutase 1; SQSTM1/p62: sequestosome 1; STED: stimulated emission depletion; STUB1: STIP1 homology and U-box containing protein 1; TARDBP/TDP-43: TAR DNA binding protein; TFEB: transcription factor EB; ..
  7. Akdemir Evrendilek G. Empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria. Int J Food Microbiol. 2015;202:35-41 pubmed publisher
    ..Laurus nobilis), cinnamon bark (Cinnamomum verum), clove (Eugenia caryophyllata), fennel (Foeniculum vulgare), hop (Humulus lupulus), Istanbul oregano (Origanum vulgare subsp...
  8. Mahli A, Koch A, Fresse K, Schiergens T, Thasler W, Schönberger C, et al. Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis. Lab Invest. 2018;98:1614-1626 pubmed publisher
    ..Iso-alpha acids (IAAs), hop-derived bitter compounds in beer, have been shown to beneficially affect different components of the metabolic ..
  9. Choi J, Jang Y, Oh J, Kim C, Hyun I. Bee Pollen-Induced Anaphylaxis: A Case Report and Literature Review. Allergy Asthma Immunol Res. 2015;7:513-7 pubmed publisher
    ..He had seasonal allergic rhinitis in autumn. Microscopic examination of the bee pollen revealed Japanese hop, chrysanthemum, ragweed, and dandelion pollens. Skin-prick with bee pollen extracts showed positive reactions at 0...
  10. Roshan P, Kulshreshtha A, Hallan V. Identification of host cellular targets of AC4 and AV2 proteins of tomato leaf curl palampur virus and their sub-cellular localization studies. Virusdisease. 2017;28:390-400 pubmed publisher
    ..Upon sequence analysis, these interactors were identified as cysteine protease, katanin p60 ATPase-containing subunit A-like, guanine deaminase, NADH dehydrogenase (ubiquinone) iron-sulfur protein, ..
  11. Marjonen H, Sierra A, Nyman A, Rogojin V, Gröhn O, Linden A, et al. Early maternal alcohol consumption alters hippocampal DNA methylation, gene expression and volume in a mouse model. PLoS ONE. 2015;10:e0124931 pubmed publisher
    ..Our MRI study revealed asymmetry of brain structures in ethanol-exposed adult offspring (P60): we detected ethanol-induced enlargement of the left hippocampus and decreased volume of the left olfactory bulb...
  12. Takada S, Dos Santos Haemmerle C, Motta Teixeira L, Machado Nils A, Lee V, Takase L, et al. Neonatal anoxia in rats: hippocampal cellular and subcellular changes related to cell death and spatial memory. Neuroscience. 2015;284:247-59 pubmed publisher
    ..Brain changes following anoxia were evaluated at postnatal days 2, 14, 21 and 60 (P2, P14, P21 and P60)...
  13. Bergsveinson J, Friesen V, Ziola B. Transcriptome analysis of beer-spoiling Lactobacillus brevis BSO 464 during growth in degassed and gassed beer. Int J Food Microbiol. 2016;235:28-35 pubmed publisher
    ..BSR) isolate of interest given its unique physiological attributes; specifically, it is highly hop-tolerant and exhibits very rapid growth in pressurized/gassed beer...
  14. Wang L, Song G, Zheng Y, Tan W, Pan J, Zhao Y, et al. Expression of Semaphorin 4A and its potential role in rheumatoid arthritis. Arthritis Res Ther. 2015;17:227 pubmed publisher
    ..Chromatin immunoprecipitation (ChIP) and siRNA targeting p50 and p60 were applied to detect the regulation of Nuclear factor kappa (NF-κB) on Sema4A...
  15. Żołnierczyk A, Mączka W, Grabarczyk M, Wińska K, Woźniak E, Anioł M. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015;103:71-82 pubmed publisher
    ..In addition, IXN shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). ..
  16. Tsai T, Huang C, Hsu K. Infantile Amnesia Is Related to Developmental Immaturity of the Maintenance Mechanisms for Long-Term Potentiation. Mol Neurobiol. 2019;56:907-919 pubmed publisher
    ..infant mice trained at postnatal day 20 (P20) displayed deficits in long-term memory retention compared to adult (P60) mice...
  17. Bashar A, Metcalfe A, Viringipurampeer I, Yanai A, Gregory Evans C, Gregory Evans K. An ex vivo gene therapy approach in X-linked retinoschisis. Mol Vis. 2016;22:718-33 pubmed
    ..For the multiple injection studies, the mice received intravitreal MSC injections at P21, P60, and P90 with data collection at P120...
  18. Forrest C, McNair K, Pisar M, Khalil O, Darlington L, Stone T. Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine. Neuroscience. 2015;310:91-105 pubmed publisher
    ..Wistar rats on embryonic days E14, E16 and E18 of gestation and the litter was allowed to develop to post-natal day P60. Western blotting revealed no changes in hippocampal expression of several proteins previously found to be altered ..
  19. Griffith C, Dayoub A, Jaranatne T, Alatrash N, Mohamedi A, Abayan K, et al. Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands. Chem Sci. 2017;8:3726-3740 pubmed publisher
    ..only partially reflected in the cytotoxicity of 32+ and 44+ in H358, HCC2998, HOP-62 and Hs766t under hypoxia (1.1% O2) relative to normoxia (18% O2)...
  20. Galvão C, Fragoso S, de Oliveira C, Forner O, Pereira R, Soares C, et al. Identification of new Corynebacterium pseudotuberculosis antigens by immunoscreening of gene expression library. BMC Microbiol. 2017;17:202 pubmed publisher
    ..pseudotuberculosis in GenBank. The genes identified were dak2, fagA, fagB, NlpC/P60 protein family and LPxTG putative protein family...
  21. Padhi A, Naik S, Sengupta S, Ganguli G, Sonawane A. Expression of Mycobacterium tuberculosis NLPC/p60 family protein Rv0024 induce biofilm formation and resistance against cell wall acting anti-tuberculosis drugs in Mycobacterium smegmatis. Microbes Infect. 2016;18:224-36 pubmed publisher
    ..We envision that Rv0024 may play a critical role in initial infection process, adherence to host cells and drug resistance. Thus, Rv0024 may be considered as a potential drug target for the treatment of tuberculosis. ..
  22. Zhai N, Jia H, Ma M, Chao Y, Guo X, Li H. Characteristics of AccSTIP1 in Apis cerana cerana and its role during oxidative stress responses. Cell Stress Chaperones. 2018;23:1165-1176 pubmed publisher
    ..Stress-induced phosphoprotein 1 (STIP1), one of the most widely studied co-chaperones, functions as an adaptor that directs Hsp90 to Hsp70-client protein ..
  23. Chmielewski T, George S, Tillman S, Moser M, Lentz T, Indelicato P, et al. Low- Versus High-Intensity Plyometric Exercise During Rehabilitation After Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2016;44:609-17 pubmed publisher
    ..and inflammation (tumor necrosis factor-α), functional performance (maximal vertical jump and single-legged hop), knee impairments (anterior knee laxity, average knee pain intensity, normalized quadriceps strength, quadriceps ..
  24. Amos Kroohs R, Bloor C, Qureshi M, Vorhees C, Williams M. Effects of developmental exposure to manganese and/or low iron diet: Changes to metal transporters, sucrose preference, elevated zero-maze, open-field, and locomotion in response to fenfluramine, amphetamine, and MK-801. Toxicol Rep. 2015;2:1046-1056 pubmed
    ..Identically treated animals were tested behaviorally at P29 or P60. The combination of FeD+MnOE increased head dips in an elevated zero-maze, reversed deficits in sucrose preference ..
  25. Xu C, Li X, Hu Y, Cui Z, Wang L, Liang L, et al. Quantitative proteomics reveals ELP2 as a regulator to the inhibitory effect of TNF-α on osteoblast differentiation. J Proteomics. 2015;114:234-46 pubmed publisher
    ..One specific protein, ELP2 (STAT3-interacting protein 1, StIP1) up-regulated in the inhibition of osteoblast differentiation by TNF-α was verified to play a critical role in ..
  26. Mishra A, Duraisamy G, Týcová A, Matoušek J. Computational exploration of microRNAs from expressed sequence tags of Humulus lupulus, target predictions and expression analysis. Comput Biol Chem. 2015;59 Pt A:131-41 pubmed publisher
    ..computational based approach was adopted for the identification and characterization of miRNAs in Humulus lupulus (hop), which is widely cultivated for use by the brewing industry and apart from, used as a medicinal herb...
  27. Han N, Xu J, Xu F, Liu Z, Yin J. The in vivo effects of a fraction from Dioscorea spongiosa on glucocorticoid-induced osteoporosis. J Ethnopharmacol. 2016;185:53-9 pubmed publisher
    ..DSE could significantly reduce the content of BGP, ALT, TRAcP, HOP/Cr and Ca/Cr, increase the content of P/Cr compared with the control group, suggesting that DSE is effective on ..
  28. Zhang D, Zhu Y, Pedrycz W, Guo Y. A Terrestrial Microbial Fuel Cell for Powering a Single-Hop Wireless Sensor Network. Int J Mol Sci. 2016;17: pubmed publisher
    ..A single-hop WSN powered by a TMFC experimental setup was designed and experimented with...
  29. Luzak B, Kassassir H, Rój E, Stanczyk L, Watala C, Golanski J. Xanthohumol from hop cones (Humulus lupulus L.) prevents ADP-induced platelet reactivity. Arch Physiol Biochem. 2017;123:54-60 pubmed publisher
    b>Hop cones (Humulus lupulus L.), very rich source of phenolic compounds, possessing anticancer, antioxidant and anti-inflammatory activities, are considered as beneficial diet ingredients improving human health...
  30. Kannampalli P, Babygirija R, Zhang J, Poe M, Li G, Cook J, et al. Neonatal bladder inflammation induces long-term visceral pain and altered responses of spinal neurons in adult rats. Neuroscience. 2017;346:349-364 pubmed publisher
    ..In adulthood (P60), the viscero-motor response (VMR) to visceral stimuli was significantly inhibited by intrathecal (i...
  31. Sbardella M, Racanicci A, Gois F, de Lima C, Migotto D, Costa L, et al. Effects of dietary hop (Humulus lupulus L.) ?-acids on quality attributes, composition and oxidative stability of pork meat. J Sci Food Agric. 2017;: pubmed publisher
    The effects of dietary levels of hop ?-acids on physical attributes, lipid oxidation and chemical composition of pork meat were evaluated. Thirty-two castrated male pigs obtained from a complete block design feeding experiment (6...
  32. Abegg K, Hermann A, Boyle C, Bouret S, Lutz T, Riediger T. Involvement of Amylin and Leptin in the Development of Projections from the Area Postrema to the Nucleus of the Solitary Tract. Front Endocrinol (Lausanne). 2017;8:324 pubmed publisher
    ..Compared to wild-type littermates, postnatal (P10) and adult (P60) IAPP-/- mice showed a significantly reduced density of AP-NTS projections...
  33. Engelen van Melick N, van Cingel R, van Tienen T, Nijhuis van der Sanden M. Functional performance 2-9 years after ACL reconstruction: cross-sectional comparison between athletes with bone-patellar tendon-bone, semitendinosus/gracilis and healthy controls. Knee Surg Sports Traumatol Arthrosc. 2017;25:1412-1423 pubmed publisher
    ..Measurements consisted of questionnaires, isokinetic peak torque and endurance tests, a hop test battery and drop jump including video analysis...
  34. Sansone V, Burge J, McDermott M, Smith P, Herr B, Tawil R, et al. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology. 2016;86:1408-1416 pubmed publisher
    ..effects of dichlorphenamide (DCP) on attack frequency and quality of life in hyperkalemic (HYP) and hypokalemic (HOP) periodic paralysis...
  35. Zult T, Gokeler A, van Raay J, Brouwer R, Zijdewind I, Hortobagyi T. An anterior cruciate ligament injury does not affect the neuromuscular function of the non-injured leg except for dynamic balance and voluntary quadriceps activation. Knee Surg Sports Traumatol Arthrosc. 2017;25:172-183 pubmed publisher
    ..and hamstring strength, voluntary quadriceps activation, star excursion balance test performance, and single-leg hop distance (all P < 0...
  36. Alves Y, Ribeiro F, Silva A. Effect of fibular repositioning taping in adult basketball players with chronic ankle instability: a randomized, placebo-controlled, crossover trial. J Sports Med Phys Fitness. 2018;58:1465-1473 pubmed publisher
    ..15 seconds of unipedal stance test with eyes closed in a force platform), functional performance (figure-of-8 hop test and lateral hop test) and neuromuscular control (peroneus longus latency time in sudden inversion) in two ..
  37. Bertelli D, Brighenti V, Marchetti L, Reik A, Pellati F. Nuclear magnetic resonance and high-performance liquid chromatography techniques for the characterization of bioactive compounds from Humulus lupulus L. (hop). Anal Bioanal Chem. 2018;410:3521-3531 pubmed publisher
    Humulus lupulus L. (hop) represents one of the most cultivated crops, it being a key ingredient in the brewing process...
  38. Tsai C, Chao A, Jung S, Lin C, Chao A, Wang T. Stress-induced phosphoprotein 1 acts as a scaffold protein for glycogen synthase kinase-3 beta-mediated phosphorylation of lysine-specific demethylase 1. Oncogenesis. 2018;7:31 pubmed publisher
    Stress-induced phosphoprotein 1 (STIP1)-a co-chaperone of heat shock proteins-promotes cell proliferation and may act as an oncogenic factor...
  39. Hawkins G, Lazarus R, Smith R, Tantisira K, Meyers D, Peters S, et al. The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. J Allergy Clin Immunol. 2009;123:1376-83.e7 pubmed publisher
    ..We sought to evaluate the genes HSPCB, HSPCA, STIP1, HSPA8, DNAJB1, PTGES3, FKBP5, and FKBP4 on corticosteroid response...
  40. Kafi M, Ben Othman J, Bagaa M, Badache N. CCS_WHMS: A Congestion Control Scheme for Wearable Health Management System. J Med Syst. 2015;39:189 pubmed publisher
    ..CCS_WHMS that ensures efficient and fair data delivery while used in the body wearable system part or in the multi-hop inter bodies wearable ones to get the destination...
  41. Singh S, Liu Y, Zhao J, Zeng X, Hou S. The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis. Nat Commun. 2016;7:10473 pubmed publisher
    ..Conversely, expressing a constitutively activated form of the Drosophila JAK kinase (hop(Tum-l)) promotes Madm nuclear translocation, and suppresses vn and integrin expression in CySCs that allows GSCs to ..
  42. Kumar A, Ito A, Hirohama M, Yoshida M, Zhang K. Identification of new SUMO activating enzyme 1 inhibitors using virtual screening and scaffold hopping. Bioorg Med Chem Lett. 2016;26:1218-23 pubmed publisher
    ..have utilized 3D-shape matching, electrostatic potential similarity evaluations and molecular docking to scaffold hop from previously known aryl urea scaffold with SUMO E1 activity to thiazole and pyrazole urea based scaffolds...
  43. Liu G, Zhu T, Zhang A, Li F, Qian W, Qian B. Heightened stress response and cognitive impairment after repeated neonatal sevoflurane exposures might be linked to excessive GABAAR-mediated depolarization. J Anesth. 2016;30:834-41 pubmed publisher
    ..neonatal sevoflurane exposures contribute to learning and memory impairment in the Morris water maze (MWM) at P60. The corticosterone level was significantly increased immediately after repeated neonatal sevoflurane exposures...
  44. Yin H, Dong J, Yu J, Li Y, Deng Y. A novel horA genetic mediated RCA detection of beer spoilage lactobacillus. Microb Pathog. 2018;114:311-314 pubmed publisher
    ..Contaminating LAB results in beer spoilage. HorA gene carried by beer spoilage lactobacillus confers hop resistance and is associated with the growth of Lactobacillus in beer, thus can be used as a perfectly valid ..
  45. Eguchi K, Hoshide S, Miyashita H, Nagasaka S, Kario K. Why the radial augmentation index is low in patients with diabetes: The J-HOP study. Atherosclerosis. 2016;246:338-43 pubmed publisher
    ..As renal function decreases, a cPP increase may overcome the increase of augmentation pressure in the DM group. ..
  46. Geist K, Bradley C, Hofman A, Koester R, Roche F, Shields A, et al. Clinical Effects of Dry Needling Among Asymptomatic Individuals With Hamstring Tightness: A Randomized Controlled Trial. J Sport Rehabil. 2017;26:507-517 pubmed publisher
    ..The first session included measurement of hamstring extensibility and performance on 4 unilateral hop tests, instruction in home hamstring stretching exercises and needling distal to the ischial tuberosity and ..
  47. Diel P, Kurrat A, Oden C, Hanke L. [Risk and benefit of nutritional supplements for the treatment of postmenopausal complaints]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017;60:297-304 pubmed publisher
    ..we have to distinguish between so-called phytoestrogens which are postulated to act via estrogen receptors such as hop extracts, soy extracts, pomegranate extracts and red clover extracts...
  48. Maruta K, Furukawa H. Highly Efficient Multi Channel Packet Forwarding with Round Robin Intermittent Periodic Transmit for Multihop Wireless Backhaul Networks. Sensors (Basel). 2017;17: pubmed publisher
    Round Robin based Intermittent Periodic Transmit (RR-IPT) has been proposed which achieves highly efficient multi-hop relays in multi-hop wireless backhaul networks (MWBN) where relay nodes are 2-dimensionally deployed...
  49. Zwolski C, Schmitt L, Thomas S, Hewett T, Paterno M. The Utility of Limb Symmetry Indices in Return-to-Sport Assessment in Patients With Bilateral Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2016;44:2030-8 pubmed publisher
    ..After being cleared for RTS, each subject completed a single-legged hop for distance (SLHD), triple hop for distance (THD), and triple-crossover hop for distance (CHD) test, in addition ..
  50. Zhang H, Sun X, Wang J, Zhang Z, Zhao H, Li H, et al. Reactive Oxygen Species-mediated Loss of Phenotype of Parvalbumin Interneurons Contributes to Long-term Cognitive Impairments After Repeated Neonatal Ketamine Exposures. Neurotox Res. 2016;30:593-605 pubmed
    ..For histological and biochemical assays, a separate cohort of rats was killed on P9 or P60, and the brain tissues were harvested...
  51. Nawasreh Z, Logerstedt D, Cummer K, Axe M, Risberg M, Snyder Mackler L. Do Patients Failing Return-to-Activity Criteria at 6 Months After Anterior Cruciate Ligament Reconstruction Continue Demonstrating Deficits at 2 Years?. Am J Sports Med. 2017;45:1037-1048 pubmed publisher
    ..The RTAC included the isometric quadriceps strength index (QI), 4 single-legged hop tests, the Knee Outcome Survey-activities of daily living subscale (KOS-ADLS), and the global rating scale of ..
  52. Stompor M, Uram Ł, Podgórski R. In Vitro Effect of 8-Prenylnaringenin and Naringenin on Fibroblasts and Glioblastoma Cells-Cellular Accumulation and Cytotoxicity. Molecules. 2017;22: pubmed publisher
    ..It should be noted that 8PN content in hop cones is 10 to 100 times lower compared to other flavonoids, such as xanthohumol...
  53. Yan D, Wong Y, Tedone L, Shellie R, Marriott P, Whittock S, et al. Chemotyping of new hop (Humulus lupulus L.) genotypes using comprehensive two-dimensional gas chromatography with quadrupole accurate mass time-of-flight mass spectrometry. J Chromatogr A. 2018;1536:110-121 pubmed publisher
    ..b>hop) essential oils. Comparison of characterised essential oils allows discrimination among chemotypes...
  54. Cho H, Kim S, Shin H, Chung E, Kitano H, Hyon Park J, et al. Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer. Genes Chromosomes Cancer. 2014;53:277-88 pubmed publisher
    Stress-induced phosphoprotein1 (STIP1) is a candidate biomarker in epithelial ovarian cancer (EOC). In this study, we investigated in detail the expression of STIP1, as well as its functions, in EOC...
  55. Noba S, Yako N, Sakai H, Kobayashi M, Watanabe T. Identification of a precursor of 2-mercapto-3-methyl-1-butanol in beer. Food Chem. 2018;255:282-289 pubmed publisher
    ..The 2M3MB precursor was found to be a volatile compound because 2M3MB was formed in the distillate of hop extract...
  56. Mosavat Jahromi H, Maham B, Tsiftsis T. Maximizing Spectral Efficiency for Energy Harvesting-Aware WBAN. IEEE J Biomed Health Inform. 2017;21:732-742 pubmed publisher
    ..We consider two scenarios for the transmission which are single- and dual-hop and achieve the power management policy for each scenario...
  57. Bassi D, Zhang J, Renner C, Klein Szanto A. Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth. Mol Carcinog. 2017;56:1182-1188 pubmed publisher
    ..present communication, we treated two furin-overexpressing non-small cell carcinoma (NSCLC) cell lines (Calu-6 and HOP-62) with the PC inhibitor CMK (Decanoyl-Arg-Val-Lys-Arg-chloromethylketone)...
  58. van Hunsel F, van de Koppel S, van Puijenbroek E. Post-Menopausal Vaginal Hemorrhage Related to the Use of a Hop-Containing Phytotherapeutic Product. Drug Saf Case Rep. 2015;2:14 pubmed
    ..developed abdominal cramps and vaginal hemorrhage as a result of endometrial hyperplasia during treatment with a hop-containing phytotherapeutic product (MenoCool®) for post-menopausal complaints...
  59. Reuter S, Forkel P, Imhoff A, Beitzel K. Postural control in elite decathlon athletes: are various modes of dynamic assessment needed?. J Sports Med Phys Fitness. 2017;57:936-941 pubmed publisher
    ..3 cm; mean weight±SD, 82.1±7.2 kg) was tested. Star Excursion Balance Test (SEBT) and three different single-leg-hop tests (SLHT) (single hop for distance [SLH], crossover hop for distance [COH], triple hop for distance [TH] were ..
  60. Yuen T, Lam P, Lau M, Siu W, Yu K, Lo C, et al. Changes in Lower Limb Strength and Function Following Lumbar Spinal Mobilization. J Manipulative Physiol Ther. 2017;40:587-596 pubmed publisher
    ..lumbar rotational mobilization on L2-3 can improve hip flexor strength and performance in the single-leg triple-hop test in asymptomatic young adults...
  61. Flosadottir V, Frobell R, Roos E, Ageberg E. Impact of treatment strategy and physical performance on future knee-related self-efficacy in individuals with ACL injury. BMC Musculoskelet Disord. 2018;19:50 pubmed publisher
    ..The participants performed physical performance tests (hop, strength and balance) at the end the of exercise therapy (mean 10 (SD 6) months), and at 5 years, and rated their ..
  62. Hernández M, Sullivan W, Toft D. The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex. J Biol Chem. 2002;277:38294-304 pubmed
    ..The protein called Hop serves as an adaptor protein for hsp70 and hsp90 and is thought to optimize their functional cooperation...
  63. Forino M, Pace S, Chianese G, Santagostini L, Werner M, Weinigel C, et al. Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv. "Cascade"). J Nat Prod. 2016;79:590-7 pubmed publisher
    Humulus lupulus (hop plant) has long been used in traditional medicine as a sedative and antimicrobial agent...
  64. Siew C. The influence of 2-hop network density on spoken word recognition. Psychon Bull Rev. 2017;24:496-502 pubmed publisher
    The influence of 2-hop density on spoken word recognition was investigated. 2-hop density measures the density of connections among the phonological neighbors (i.e., 1-hop neighbors) and phonological neighbors of those neighbors (i.e...
  65. Kim K, Kim M, Choe H, Han M, Lee H, Oh J, et al. A biology-driven receptor model for daily pollen allergy risk in Korea based on Weibull probability density function. Int J Biometeorol. 2017;61:259-272 pubmed publisher
    ..4-88.2 % and 92.5-98.5 % for oak and Japanese hop pollens, respectively...
  66. Chen C, Rasmussen H, Kamil A, Du P, Blumberg J. Orange Pomace Improves Postprandial Glycemic Responses: An Acute, Randomized, Placebo-Controlled, Double-Blind, Crossover Trial in Overweight Men. Nutrients. 2017;9: pubmed publisher
    ..trial with 34 overweight men who consumed either a 255 g placebo (PLA), a low (35% OP (LOP)), or a high (77% (HOP)) dose OP beverage with breakfast. Blood was collected at 0, 10, 20, 30, and 45 min and at 1, 1.5, 2, 3, 4, 5, 5...
  67. Arundale A, Cummer K, Capin J, Zarzycki R, Snyder Mackler L. Report of the Clinical and Functional Primary Outcomes in Men of the ACL-SPORTS Trial: Similar Outcomes in Men Receiving Secondary Prevention With and Without Perturbation Training 1 and 2 Years After ACL Reconstruction. Clin Orthop Relat Res. 2017;475:2523-2534 pubmed publisher
    ..with the addition of perturbation training) groups with respect to (1) quadriceps strength and single-legged hop limb symmetry; (2) patient-reported knee outcome scores; (3) the proportion who achieve self-reported normal knee ..
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    ..the S100 proteins carry out a range of roles, the interaction of S100A1 and the stress-inducible phosphoprotein 1 (STIP1) has been shown to be particularly important. A recent study by Maciejewski et al...
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    ..Commonly, this is carried out utilizing head out plethysmography (HOP) or whole body plethysmography (WBP) which record only ventilatory parameters...
  70. Yang L, Broderick D, Campbell Y, Gombart A, Stevens J, Jiang Y, et al. Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies. Biochim Biophys Acta. 2016;1864:1667-1677 pubmed publisher
    ..We and others have shown that xanthohumol (XN), the principal prenylflavonoid of the hop plant (Humulus lupulus L...
  71. Graumann K, Jungbauer A. Quantitative assessment of complex formation of nuclear-receptor accessory proteins. Biochem J. 2000;345 Pt 3:627-36 pubmed
    ..The interaction kinetics and dynamics of hsp90, hsp70, p60 (Hop), FKBP52, FKBP51, p48 (Hip) and p23 have been assessed by a biosensor approach measuring the complex formation in ..
  72. Scholz G, Cartledge K, Hall N. Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37. J Biol Chem. 2001;276:30971-9 pubmed
    ..Thus Harc likely represents a novel participant in Hsp90-mediated protein folding, potentially targeting Hsp90 to Hsp70-client protein heterocomplexes. ..
  73. Lechuga S, Naydenov N, Feygin A, Jiménez A, Ivanov A. A vesicle trafficking protein αSNAP regulates Paneth cell differentiation in vivo. Biochem Biophys Res Commun. 2017;486:951-957 pubmed publisher
    ..In the present study, we used a mouse with a spontaneous hydrocephalus with hop gait (hyh) mutation of αSNAP to examine the roles of this trafficking protein in regulating intestinal ..
  74. Ebert J, Edwards P, Yi L, Joss B, Ackland T, Carey Smith R, et al. Strength and functional symmetry is associated with post-operative rehabilitation in patients following anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2018;26:2353-2361 pubmed publisher
    ..the Noyes Activity Score (NSARS), maximal isokinetic knee extensor and flexor strength assessment, and a 4-hop test battery...
  75. Harrison J, Yorgey M, Csiernik A, Vogler J, Games K. Clinician-Friendly Physical Performance Tests for the Knee. J Athl Train. 2017;: pubmed publisher
    ..Part 1: the tests for knee function including the hop tests. Br J Sports Med. 2015;49(10):642-648.
  76. Muller P, Růcková E, Halada P, Coates P, Hrstka R, Lane D, et al. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances. Oncogene. 2013;32:3101-10 pubmed publisher
    ..The mechanisms regulating these opposite activities involve Hsp binding to co-chaperones including CHIP and HOP at their C-termini...
  77. Lavudi S, Oberoi H, Mangamoori L. Ethanol production from sweet sorghum bagasse through process optimization using response surface methodology. 3 Biotech. 2017;7:233 pubmed publisher
    ..fermentation (SSF) as well as separated hydrolysis and fermentation (SHF) was evaluated using Pichia kudriavzevii HOP-1 for production of ethanol...
  78. Schroeder K, Jia H, Wang Y, Smaldone A. Implementation of a School Nurse-led Intervention for Children With Severe Obesity in New York City Schools. J Pediatr Nurs. 2017;35:16-22 pubmed publisher
    The Healthy Options and Physical Activity Program (HOP) is a school nurse-led intervention for children with severe obesity...
  79. Ling P, Holmes L, Jordan J, Lisha N, Bibbins Domingo K. Bars, Nightclubs, and Cancer Prevention: New Approaches to Reduce Young Adult Cigarette Smoking. Am J Prev Med. 2017;53:S78-S85 pubmed publisher
    ..17, 95% CI=1.59, 6.32) were associated with greater odds of smoking, as was affiliation with "Hip Hop" (AOR=4.32, 95% CI=1.48, 12.67) and "Country" (AOR=3.13, 95% CI=1.21, 8.09) peer crowds...
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    ..the velocities are adjusted along the direction of the NACV to satisfy total energy conservation upon a surface hop. This criterion produces the right fraction of energy-forbidden (frustrated) hops, which is essential for correct ..
  81. Walker V, Atanasiu R, Lam H, Shrier A. Co-chaperone FKBP38 promotes HERG trafficking. J Biol Chem. 2007;282:23509-16 pubmed
    ..chaperone system, including Hsc70 (70-kDa heat shock cognate protein), Hsp90 (90-kDa heat shock protein), Hdj-2, Hop (Hsp-organizing protein), and Bag-2 (BCL-associated athanogene 2)...
  82. Tsai C, Chao A, Jung S, Tsai C, Lin C, Chen S, et al. Stress-induced phosphoprotein-1 maintains the stability of JAK2 in cancer cells. Oncotarget. 2016;7:50548-50563 pubmed publisher
    Overexpression of stress-induced phosphoprotein 1 (STIP1) - a co-chaperone of heat shock protein (HSP) 70/HSP90 - and activation of the JAK2-STAT3 pathway occur in several tumors...
  83. Gul O, Demirekler M. Average Throughput Performance of Myopic Policy in Energy Harvesting Wireless Sensor Networks. Sensors (Basel). 2017;17: pubmed publisher
    This paper considers a single-hop wireless sensor network where a fusion center collects data from M energy harvesting wireless sensors. The harvested energy is stored losslessly in an infinite-capacity battery at each sensor...
  84. Takazumi K, Takoi K, Koie K, Tuchiya Y. Quantitation Method for Polyfunctional Thiols in Hops (Humulus lupulus L.) and Beer Using Specific Extraction of Thiols and Gas Chromatography-Tandem Mass Spectrometry. Anal Chem. 2017;89:11598-11604 pubmed publisher
    ..The method was applied to quantitation of hops and beer flavored with thiol-containing hop varieties...
  85. Lozano T, Gorraiz M, Lasarte Cía A, Ruiz M, Rabal O, Oyarzabal J, et al. Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor. Oncotarget. 2017;8:71709-71724 pubmed publisher
    ..In a previous work we identified a peptide (named P60) able to enter into the cells, bind to FOXP3, and impair Treg activity in vitro and in vivo...
  86. Weaver A, Sullivan W, Felts S, Owen B, Toft D. Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone. J Biol Chem. 2000;275:23045-52 pubmed
    ..However, the tail is necessary for optimum active chaperoning of the progesterone receptor, as well as the passive chaperoning activity of p23 in assays measuring inhibition of heat-induced protein aggregation. ..
  87. Zheng D, Wang X, Antonson P, Gustafsson J, Li Z. Genomics of sex hormone receptor signaling in hepatic sexual dimorphism. Mol Cell Endocrinol. 2018;471:33-41 pubmed publisher
    ..5 to the postnatal stage P60 during liver development...
  88. Cai W, Zhang M, Zheng Y. Task Assignment and Path Planning for Multiple Autonomous Underwater Vehicles Using 3D Dubins Curves †. Sensors (Basel). 2017;17: pubmed publisher
    ..Genetic Algorithm (GA) is used to solve the MTSP problem with Euclidean distance as the cost function and the Tour Hop Balance (THB) or Tour Length Balance (TLB) constraints as the stop criterion...
  89. Sueyoshi T, Nakahata A, Emoto G, Yuasa T. Single-Leg Hop Test Performance and Isokinetic Knee Strength After Anterior Cruciate Ligament Reconstruction in Athletes. Orthop J Sports Med. 2017;5:2325967117739811 pubmed publisher
    Isokinetic strength and hop tests are commonly used to assess athletes' readiness to return to sport after knee surgery.
  90. Vural B, Uğurel E, Tuzun E, Kurtuncu M, Zuliani L, Cavuş F, et al. Anti-neuronal and stress-induced-phosphoprotein 1 antibodies in neuro-Behçet's disease. J Neuroimmunol. 2011;239:91-7 pubmed publisher
    ..High-titer STIP-1-antibodies were detected in 6 NBD patients' sera but not in controls. These results suggest that neuronal antibodies could be useful as diagnostic biomarkers in NBD. ..
  91. Chao A, Lee L, Hsueh C, Lin C, Tsai C, Chao A, et al. Immunohistological analysis of stress-induced phosphoprotein 1 in ovarian cancer patients with low serum cancer antigen 125 levels. Taiwan J Obstet Gynecol. 2013;52:185-91 pubmed publisher
    Stress-induced phosphoprotein 1 (STIP1) was recently identified as a potential tumor marker for human ovarian cancer. This study further evaluates the usefulness of STIP1 in ovarian tumor patients with normal CA125 serum levels...
  92. Mazziotti R, Lupori L, Sagona G, Gennaro M, Della Sala G, Putignano E, et al. Searching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice. Hum Mol Genet. 2017;26:2290-2298 pubmed publisher
    ..The previously imaged mice were also analyzed at P60-80 using VEPs, revealing a persistent reduction of response amplitude, reduced visual acuity and defective contrast ..