SNRPG

Summary

Gene Symbol: SNRPG
Description: small nuclear ribonucleoprotein polypeptide G
Alias: SMG, Sm-G, small nuclear ribonucleoprotein G, sm protein G, snRNP-G
Species: human
Products:     SNRPG

Top Publications

  1. Hermann H, Fabrizio P, Raker V, Foulaki K, Hornig H, Brahms H, et al. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions. EMBO J. 1995;14:2076-88 pubmed
  2. Sleeman J, Lamond A. Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Curr Biol. 1999;9:1065-74 pubmed
    ..These include speckles, coiled bodies and nucleoli, in addition to a diffuse nucleoplasmic compartment. The reasons for snRNP accumulation in these different structures are unclear...
  3. Charroux B, Pellizzoni L, Perkinson R, Shevchenko A, Mann M, Dreyfuss G. Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. J Cell Biol. 1999;147:1181-94 pubmed
    ..The presence of a DEAD box motif in Gemin3 suggests that it may provide the catalytic activity that plays a critical role in the function of the SMN complex on RNPs. ..
  4. Weber G, Trowitzsch S, Kastner B, Luhrmann R, Wahl M. Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO J. 2010;29:4172-84 pubmed publisher
    ..The intricate, multi-layered interplay of proteins and RNA rationalizes the hierarchical assembly of U snRNPs in vitro and in vivo. ..
  5. Liu Q, Fischer U, Wang F, Dreyfuss G. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell. 1997;90:1013-21 pubmed
    ..These findings suggest a role for SMN and SIP1 in spliceosomal snRNP biogenesis and function and provide a likely molecular mechanism for the cause of SMA. ..
  6. Urlaub H, Raker V, Kostka S, Luhrmann R. Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. EMBO J. 2001;20:187-96 pubmed
    ..Our results thus provide the first evidence that, within the core snRNP, multiple Sm protein-Sm site RNA contacts occur on the inner surface of the heptameric Sm protein ring. ..
  7. Xu T, Lu C, Feng L, Fan L, Sun J, Fan B, et al. Liquid chromatography-mass spectrometry-based urinary metabolomics study on a rat model of simulated microgravity-induced depression. J Pharm Biomed Anal. 2019;165:31-40 pubmed publisher
    ..The depression model of rats was induced by 14-d simulated microgravity (SMG) treatment...
  8. Zeidan Y, Xiao N, Cao H, Kong C, Le Q, Sirjani D. Botulinum Toxin Confers Radioprotection in Murine Salivary Glands. Int J Radiat Oncol Biol Phys. 2016;94:1190-7 pubmed publisher
    ..05). Cell death detected by TUNEL staining was similar in SMG sections of both groups...
  9. Liu S, Liu Y, Ma Q, Cui S, Liu J. Expression and localization of cysteine sulfinate decarboxylase in major salivary glands of male mice. Arch Oral Biol. 2015;60:615-21 pubmed publisher
    ..The relative levels of CSD mRNA increase from the submandibular gland (SMG) to the sublingual gland (SLG) and parotid gland (PG), but the levels of the CSD protein are the opposite...

More Information

Publications124 found, 100 shown here

  1. Ding C, Du Z, Li S, Wu L, Yu G. Ca2+-CaMKK? pathway is required for adiponectin-induced secretion in rat submandibular gland. J Mol Histol. 2018;49:99-110 pubmed publisher
    ..Furthermore, in cultured SMG-C6 cells, co-pretreatment with EGTA and TG suppressed fAd-decreased transepithelial electrical resistance and ..
  2. Huang S, Lee T, Lin Y, Wan L, Lai C, Lin C. Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism. J Microbiol Immunol Infect. 2017;50:277-285 pubmed publisher
    ..pore complex interacting protein family, member B3; also named as phosphatidylinositol-3-kinase-related kinase SMG-1 isoform 1 homolog)...
  3. De Cicco M, Rahim M, Dames S. Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting. Membranes (Basel). 2015;5:553-75 pubmed publisher
    ..ATR), DNA-dependent protein kinase catalytic subunit (DNA-PKcs), suppressor of morphogenesis in genitalia-1 (SMG-1), and transformation/transcription domain-associated protein (TRRAP)...
  4. Cong X, Zhang Y, He Q, Wei T, Zhang X, Zhang J, et al. Endothelial Tight Junctions Are Opened in Cholinergic-Evoked Salivation In Vivo. J Dent Res. 2017;96:562-570 pubmed publisher
    ..the lateral and basolateral membranes and cytoplasm in cholinergic-stimulated mouse SMGs and freshly cultured human SMG tissues...
  5. May A, Teshima T, Noble A, Tucker A. FGF10 is an essential regulator of tracheal submucosal gland morphogenesis. Dev Biol. 2019;: pubmed publisher
    ..The SMG mucus is rich in mucins and antimicrobial enzymes...
  6. Dai Z, Guo F, Wu F, Xu H, Yang C, Li J, et al. Integrin αvβ3 mediates the synergetic regulation of core-binding factor α1 transcriptional activity by gravity and insulin-like growth factor-1 through phosphoinositide 3-kinase signaling. Bone. 2014;69:126-32 pubmed publisher
    ..with a 6OSE2 (Osteoblast-Specific Element 2)-luciferase reporter and cultured under simulated microgravity (SMG) and hypergravity (HG) conditions in the presence or absence of IGF-1, the disintegrin echistatin, the ..
  7. Nakata H, Yamamoto M, Kumchantuek T, Adhapanyawanich K, Nishiuchi T, Iseki S. Synthesis, localization and possible function of serine (or cysteine) peptidase inhibitor, clade B, member 6a (Serpinb6a) in mouse submandibular gland. Cell Tissue Res. 2017;369:513-526 pubmed publisher
    The granular convoluted tubule (GCT) in the duct system of the submandibular gland (SMG) develops preferentially in male mice and produces a number of bioactive peptides including proteases such as renin and kallikrein...
  8. Yamamoto M, Nakata H, Kumchantuek T, Adhapanyawanich K, Iseki S. Distinct hormonal regulation of two types of sexual dimorphism in submandibular gland of mice. Cell Tissue Res. 2018;371:261-272 pubmed publisher
    The submandibular gland (SMG) of mice exhibits prominent sexual dimorphism in two aspects: the preferential development of granular convoluted tubule (GCT) cells and the earlier disappearance of granular intercalated duct (GID) cells in ..
  9. Khalafalla M, Woods L, Camden J, Khan A, Limesand K, Petris M, et al. P2X7 receptor antagonism prevents IL-1? release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy. J Biol Chem. 2017;292:16626-16637 pubmed publisher
    ..Here, our results show that in primary mouse submandibular gland (SMG) epithelial cells, P2X7R activation also induces the assembly of the NLRP3 inflammasome and the maturation and ..
  10. Hannan F, Howles S, Rogers A, Cranston T, Gorvin C, Babinsky V, et al. Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects. Hum Mol Genet. 2015;24:5079-92 pubmed publisher
    ..FHH3 probands had significantly greater serum calcium (sCa) and magnesium (sMg) concentrations with reduced urinary calcium to creatinine clearance ratios (CCCR) in comparison with FHH1 probands ..
  11. May A, Headon D, Rice D, Noble A, Tucker A. FGF and EDA pathways control initiation and branching of distinct subsets of developing nasal glands. Dev Biol. 2016;419:348-356 pubmed publisher
    Hypertrophy, hyperplasia and altered mucus secretion from the respiratory submucosal glands (SMG) are characteristics of airway diseases such as cystic fibrosis, asthma and chronic bronchitis...
  12. Togarrati P, Sasaki R, Abdel Mohsen M, Dinglasan N, Deng X, Desai S, et al. Identification and characterization of a rich population of CD34+ mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands. Sci Rep. 2017;7:3484 pubmed publisher
    ..CD34 was widely expressed by the MSCs of human major SGs, namely parotid (PAG), sublingual (SLG) and submandibular (SMG) glands...
  13. Cong X, Zhang Y, Yang N, Li J, Ding C, Ding Q, et al. Occludin is required for TRPV1-modulated paracellular permeability in the submandibular gland. J Cell Sci. 2013;126:1109-21 pubmed publisher
    ..explored the role of occludin in TRPV1-modulated paracellular permeability in a rat submandibular gland cell line SMG-C6...
  14. Lau I, Potluri A, Ibeh C, Redman R, Paal E, Bandyopadhyay B. Microcalcifications in stone-obstructed human submandibular gland are associated with apoptosis and cell proliferation. Arch Oral Biol. 2017;82:99-108 pubmed publisher
    Human submandibular gland (SMG) stones are associated with inflammation, fibrosis and microcalcifications in the surrounding tissues...
  15. Tachow A, Thoungseabyoun W, Phuapittayalert L, Petcharat K, Sakagami H, Kondo H, et al. Co-localization of endogenous Arf6 and its activator EFA6D in the granular convoluted tubule cells of mouse submandibular glands under normal conditions and when stimulated by isoproterenol, noradrenaline and carbachol. Arch Oral Biol. 2017;82:153-159 pubmed publisher
    ..at light and electron microscopic levels of Arf6 and its activator EFA6D in the mouse submandibular gland (SMG) under normal conditions and when stimulated by adrenergic or cholinergic agonists...
  16. Zhang L, Cong X, Zhang Y, Wei T, Su Y, Serrão A, et al. Interleukin-17 Impairs Salivary Tight Junction Integrity in Sjögren's Syndrome. J Dent Res. 2016;95:784-92 pubmed publisher
    ..vitro, IL-17 significantly decreased the levels and apical staining of claudin-4 and ZO-1 proteins in the cultured SMG tissues, as well as claudin-1, occludin, and ZO-1 in PG tissues...
  17. Rawangwong A, Pidsaya A, Thoungseabyoun W, Tachow A, Sawatpanich T, Sakaew W, et al. Localization of phospholipase C β3 in the major salivary glands of adult mice. Acta Histochem. 2019;: pubmed publisher
    ..immunoblots of the parotid and sublingual glands (PG, SLG), while no such band was seen in the submandibular gland (SMG). No bands were detected for PLCβ1 or 4 in the three glands...
  18. Abe A, Takano K, Kojima T, Nomura K, Kakuki T, Kaneko Y, et al. Interferon-gamma increased epithelial barrier function via upregulating claudin-7 expression in human submandibular gland duct epithelium. J Mol Histol. 2016;47:353-63 pubmed publisher
    ..We examined submandibular gland (SMG) tissue from eight control individuals and 22 patients with IgG4-RD and established an HSDEC culture system...
  19. Elsherbini A, Mohammed M, Ibrahim F. Effect of Biochanin A versus 17? estradiol in rat submandibular salivary gland. J Oral Sci. 2017;: pubmed publisher
    ..The submandibular gland (SMG) presents as a great model due to extensive postnatal development, and is known to be regulated and affected by ..
  20. Knopf A, Hofauer B, Thürmel K, Meier R, Stock K, Bas M, et al. Diagnostic utility of Acoustic Radiation Force Impulse (ARFI) imaging in primary Sjoegren`s syndrome. Eur Radiol. 2015;25:3027-34 pubmed publisher
    ..All patients underwent high-resolution ultrasound and ARFI imaging of the parotid (PG) and submandibular glands (SMG). Seventy patients were classified as having pSS...
  21. Maruyama C, Leigh N, Nelson J, McCall A, Mellas R, Lei P, et al. Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters. J Dent Res. 2015;94:1610-7 pubmed publisher
    ..However, the hHF-MSC conditioned medium enhanced cell organization and multilumen formation, indicating that soluble signals secreted by hHF-MSCs play a role in promoting these features. ..
  22. Magara S, Komatsubara T, Hojo M, Kobayashi Y, Yoshino M, Saitoh A, et al. The association of epileptic focus estimated by magnetoencephalography with cognitive function in non-lesional epilepsy with continuous spikes and waves during slow wave sleep (ECSWS) children. Brain Dev. 2019;41:163-172 pubmed publisher
    ..The dipole clusters were estimated on the right Rolandic area (RA) in 4 patients (25%), right supramarginal gyrus (SMG) in 3 (19%), left RA in 2 (13%), left SMG in 2 (13%), bilateral RA in 3 (19%), multiple anatomical locations in 2 (..
  23. Paul M, Burt D, Krieger J, Nakamura N, Dzau V. Tissue specificity of renin promoter activity and regulation in mice. Am J Physiol. 1992;262:E644-50 pubmed
    ..start sites in renal and extrarenal tissues [adrenal, brain, testis, heart, and submandibular gland (SMG)] and examined the effect of adenosine 3',5'-cyclic monophosphate (cAMP) on tissue specific promoter usage...
  24. Morales M, Martín Galiano A, Domenech M, García E. Insights into the Evolutionary Relationships of LytA Autolysin and Ply Pneumolysin-Like Genes in Streptococcus pneumoniae and Related Streptococci. Genome Biol Evol. 2015;7:2747-61 pubmed publisher
    ..The lytA- and ply-related genes are also found in other streptococci of the Mitis group (SMG)...
  25. Mei M, Xiang R, Cong X, Zhang Y, Li J, Yi X, et al. Claudin-3 is required for modulation of paracellular permeability by TNF-α through ERK1/2/slug signaling axis in submandibular gland. Cell Signal. 2015;27:1915-27 pubmed publisher
    ..TNF-α reduced transepithelial resistance (TER) and increased FITC-dextran flux in a rat submandibular cell line SMG-C6...
  26. Zhang X, Yang N, Liu X, Su J, Cong X, Wu L, et al. Autonomic reinnervation and functional regeneration in autologous transplanted submandibular glands in patients with severe keratoconjunctivitis sicca. Int J Oral Sci. 2018;10:14 pubmed publisher
    Autologous submandibular gland (SMG) transplantation has been proved to ameliorate the discomforts in patients with severe keratoconjunctivitis sicca...
  27. Saghiri M, Asatourian A, Gurel Z, Sorenson C, Sheibani N. Bcl-2 expression is essential for development and normal physiological properties of tooth hard tissue and saliva production. Exp Cell Res. 2017;358:94-100 pubmed publisher
    ..Although expression of Bcl-2 has been reported during tooth and submandibular gland (SMG) development, the physiological role Bcl-2 plays during these processes has not been addressed...
  28. Son H, Seo M, Ham S, Hwang W, Lee D, An S, et al. RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans. Nat Commun. 2017;8:14749 pubmed publisher
    ..NMD components, including smg-2/UPF1, are required to achieve the longevity of several long-lived mutants, including daf-2 mutant worms...
  29. Lee D, Jung K, Baek S. Endoscopic submandibular gland resection preserving great auricular nerve and periaural sensation. Auris Nasus Larynx. 2016;43:89-92 pubmed publisher
    ..The aim of this study is to describe the surgical technique of endoscopic submandibular gland (SMG) resection through the potential plane between great auricular nerve (GAN) and sternocleidomastoid muscle (sub-GAN ..
  30. Sathi G, Farahat M, Hara E, Taketa H, Nagatsuka H, Kuboki T, et al. MCSF orchestrates branching morphogenesis in developing submandibular gland tissue. J Cell Sci. 2017;130:1559-1569 pubmed publisher
    ..5, at a stage preceding the colonization of macrophages (at E15.5), in mouse submandibular gland (SMG) tissue...
  31. Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al. Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014;5:e1478 pubmed publisher
    ..inhibitor CDKN1A/p21 and activation of senescence-associated β-galactosidase were detected in the stressed SMG duct cells...
  32. Newsome H, Mandapathil M, Koh Y, Duvvuri U. Utility of the Highly Articulated Flex Robotic System for Head and Neck Procedures: A Cadaveric Study. Ann Otol Rhinol Laryngol. 2016;125:758-63 pubmed publisher
    ..for head and neck procedures, including a postauricular facelift approach thyroidectomy, submandibular gland (SMG) removal, and cervical lymphadenectomy...
  33. Li J, Leung A, Kondo Y, Oubridge C, Nagai K. Re-refinement of the spliceosomal U4 snRNP core-domain structure. Acta Crystallogr D Struct Biol. 2016;72:131-46 pubmed publisher
    ..The U4 Sm site-sequence AAUUUUU has been shown to bind to the seven Sm proteins SmF-SmE-SmG-SmD3-SmB-SmD1-SmD2 in an identical manner as the U1 Sm-site sequence AAUUUGU, except in SmD1 where the bound U ..
  34. Zyablitskaya M, Munteanu E, Nagasaki T, Paik D. Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking (TXL) for Myopia. J Vis Exp. 2018;: pubmed publisher
    ..The chemical cross-linking agent, sodium hydroxymethylglycinate (SMG), is from a class of cosmetic preservatives known as formaldehyde releasing agents (FARs)...
  35. Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, et al. Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016;477:814-819 pubmed publisher
    The mouse submandibular gland (SMG) is important organ for embryonic development, and branching morphogenesis is regulated by many molecules containing transcription factors...
  36. Buhler D, Raker V, Luhrmann R, Fischer U. Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. Hum Mol Genet. 1999;8:2351-7 pubmed
    ..Thus, our data show that SMN is an essential U snRNP assembly factor and establish a direct correlation between defects in the biogenesis of U snRNPs and SMA. ..
  37. Yamamoto M, Nakata H, Kumchantuek T, Sakulsak N, Iseki S. Immunohistochemical localization of keratin 5 in the submandibular gland in adult and postnatal developing mice. Histochem Cell Biol. 2016;145:327-39 pubmed publisher
    ..During prenatal development of the submandibular gland (SMG) in mice, K5(+) progenitor cells in the developing epithelia play important roles in its organogenesis...
  38. Conte N, Delaval B, Ginestier C, Ferrand A, Isnardon D, Larroque C, et al. TACC1-chTOG-Aurora A protein complex in breast cancer. Oncogene. 2003;22:8102-16 pubmed
  39. Li X, Wu W, Xing R, Wong S, Liu Y, Fang X, et al. Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability. Cancer Res. 2016;76:1724-32 pubmed publisher
    ..information from 544 gastric cancer patients from previous genomic studies to identify significantly mutated genes (SMG) with prognostic relevance. Gastric cancer patients were classified into regular (86.8%) and hypermutated (13...
  40. Huangfu J, Xu Y, Li C, Li J. Overexpressing target helper genes enhances secretion and glycosylation of recombinant proteins in Pichia pastoris under simulated microgravity. J Ind Microbiol Biotechnol. 2016;43:1429-39 pubmed publisher
    ..of transcriptomic and proteomic profiling in recombinant Pichia pastoris cultured under simulated microgravity (SMG)...
  41. Xu H, Wu F, Zhang H, Yang C, Li K, Wang H, et al. Actin cytoskeleton mediates BMP2-Smad signaling via calponin 1 in preosteoblast under simulated microgravity. Biochimie. 2017;138:184-193 pubmed publisher
    ..we demonstrated actin microfilament mediated osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity (SMG)...
  42. Yang P, Fan C, Wang M, Fogelson N, Li L. The effects of changes in object location on object identity detection: A simultaneous EEG-fMRI study. Neuroimage. 2017;157:351-363 pubmed publisher
    ..greater activation of the right inferior frontal gyrus (IFG) and less suppression of the right supramarginal gyrus (SMG), when object location was repeated compared to when it was changed...
  43. Xiao J, Sun H, Qiao Q, Bao X, Wu C, Zhou Q. Advantages of submandibular gland preservation surgery over submandibular gland resection for proximal submandibular stones. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018;125:e113-e117 pubmed publisher
    This study sought to compare surgical outcomes after the removal of submandibular gland (SMG) stones via 2 different surgical methods...
  44. Schwer B, Kruchten J, Shuman S. Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring. RNA. 2016;22:1320-8 pubmed publisher
    ..guide mutagenesis in Saccharomyces cerevisiae, we gained new insights into structure-function relationships of the SmG, SmE, and SmF subunits...
  45. Keshinro A, Hatzaras I, Rifkind K, Dhage S, Joseph K. The Impact of Primary Care Providers on Patient Screening Mammography and Initial Presentation in an Underserved Clinical Setting. Ann Surg Oncol. 2017;24:692-697 pubmed publisher
    Cancer screening is a key component of primary care, and access to regular screening mammography (SMG) is highly dependent on recommendation and referral by a primary care provider (PCP)...
  46. Fofana B, Ghose K, McCallum J, You F, Cloutier S. UGT74S1 is the key player in controlling secoisolariciresinol diglucoside (SDG) formation in flax. BMC Plant Biol. 2017;17:35 pubmed publisher
    ..However, not much was reported on the biosynthesis of SDG and its monoglucoside (SMG) until lately. Flax UGT74S1 was recently reported to sequentially glucosylate SECO into SMG and SDG in vitro...
  47. Yousuf M, Heldmann M, Göttlich M, Münte T, Doñamayor N. Neural processing of food and monetary rewards is modulated by metabolic state. Brain Imaging Behav. 2018;12:1379-1392 pubmed publisher
    ..Furthermore, the interaction between metabolic state and incentive type resulted in supramarginal gyrus (SMG) activity, among other motor and sensory-related regions...
  48. Dhulekar N, Ray S, Yuan D, Baskaran A, Oztan B, Larsen M, et al. Prediction of Growth Factor-Dependent Cleft Formation During Branching Morphogenesis Using A Dynamic Graph-Based Growth Model. IEEE/ACM Trans Comput Biol Bioinform. 2016;13:350-64 pubmed publisher
    ..cleft formation during the early stages of branching morphogenesis in mouse submandibular salivary glands (SMG) under the influence of varied concentrations of epidermal growth factors (EGF)...
  49. Arlov Ø, Skjåk Bræk G, Rokstad A. Sulfated alginate microspheres associate with factor H and dampen the inflammatory cytokine response. Acta Biomater. 2016;42:180-188 pubmed publisher
    ..In the present work we designed novel microbeads and microcapsules based on sulfated polyalternating MG alginate (SMG) and explored their inflammatory properties using a human whole blood model...
  50. Baio J, Martinez A, Bailey L, Hasaniya N, Pecaut M, Kearns Jonker M. Spaceflight Activates Protein Kinase C Alpha Signaling and Modifies the Developmental Stage of Human Neonatal Cardiovascular Progenitor Cells. Stem Cells Dev. 2018;: pubmed publisher
    ..Using simulated microgravity (SMG) generated via two-dimensional clinorotation and culture aboard the International Space Station (ISS), we assessed ..
  51. Shah Basak P, Chen P, Caulfield K, Medina J, Hamilton R. The role of the right superior temporal gyrus in stimulus-centered spatial processing. Neuropsychologia. 2018;113:6-13 pubmed publisher
    ..and after (post-rTMS) receiving 20 min of 1 Hz rTMS over the right STG, the right supramarginal gyrus (SMG), and the vertex (a control site) during three separate visits...
  52. Arias Palomo E, Yamashita A, Fernández I, Núñez Ramírez R, Bamba Y, Izumi N, et al. The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. Genes Dev. 2011;25:153-64 pubmed publisher
    ..NMD also influences the expression of many physiological transcripts. SMG-1 is a large kinase essential to NMD that phosphorylates Upf1, which seems to be the definitive signal triggering ..
  53. Williams J, Darcy I, Newman S. Bimodal bilingualism as multisensory training?: Evidence for improved audiovisual speech perception after sign language exposure. Brain Res. 2016;1633:101-110 pubmed publisher
    ..Results indicated increased activation in the supramarginal gyrus (SMG) after sign language exposure, which suggests concomitant increased phonological processing of speech...
  54. Hanaie R, Mohri I, Kagitani Shimono K, Tachibana M, Matsuzaki J, Hirata I, et al. White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder: A voxel-based morphometry study. Autism Res. 2016;9:981-92 pubmed publisher
    ..test score on the M-ABC 2 and the volume of WM in the brainstem and WM adjacent to the left supramarginal gyrus (SMG)...
  55. Woo Y, Wang T, Guadalupe T, Nebel R, Vino A, Del Bene V, et al. A Common CYFIP1 Variant at the 15q11.2 Disease Locus Is Associated with Structural Variation at the Language-Related Left Supramarginal Gyrus. PLoS ONE. 2016;11:e0158036 pubmed publisher
    ..b>SMG), a cortical structure implicated in speech and language in independent discovery (n = 100) and validation cohorts (..
  56. Markey J, Morrel W, Wang S, Ryan W. The effect of submandibular gland preservation during level 1B neck dissection on postoperative xerostomia. Auris Nasus Larynx. 2018;45:123-127 pubmed publisher
    ..the presence and degree of postoperative xerostomia following preservation or excision of the submandibular gland (SMG) during level IB neck dissection (ND) without adjuvant radiation...
  57. Leigh N, Nelson J, Mellas R, McCall A, Baker O. Three-dimensional cultures of mouse submandibular and parotid glands: a comparative study. J Tissue Eng Regen Med. 2017;11:618-626 pubmed publisher
    ..An alternative option relies in the use of mouse submandibular glands (SMG), which are more anatomically accessible and yield a larger number of cells...
  58. Ashare R, Lerman C, Cao W, Falcone M, Bernardo L, Ruparel K, et al. Nicotine withdrawal alters neural responses to psychosocial stress. Psychopharmacology (Berl). 2016;233:2459-67 pubmed publisher
    ..contrast: inferior frontal gyrus (IFG), anterior/para cingulate cortex (ACC), precuneus, and supramarginal gyrus (SMG). In all regions, the deprived group showed significantly greater activation compared to the non-deprived group...
  59. Anderson P, Lynch T, Engelhardt J. Multipotent Myoepithelial Progenitor Cells Are Born Early during Airway Submucosal Gland Development. Am J Respir Cell Mol Biol. 2017;56:716-726 pubmed publisher
    ..Airway submucosal glands (SMGs) are facultative stem cell niches for the surface epithelium, but the phenotype of the SMG-derived progenitor cells remains unclear...
  60. Sharp K, Crampin E, Sneyd J. A spatial model of fluid recycling in the airways of the lung. J Theor Biol. 2015;382:198-215 pubmed publisher
    ..We present a spatial mathematical model that reflects in vivo fluid recycling via submucosal gland (SMG) secretion, and absorption through surface epithelia...
  61. Liu X, Li M, Su J, Wang Z, Xie Z, Yu G. Carbachol improves the secretion of transplanted submandibular glands during the latent period after microvascular autologous transplantation for severe keratoconjunctivitis sicca. Int J Oral Maxillofac Surg. 2016;45:1273-9 pubmed publisher
    ..The objective of this study was to investigate the efficacy and systemic side effects of carbachol on transplanted SMG secretion...
  62. Woo S, Park J, Kwon M, Kim J. "Hidden scar" submandibular gland excision using an endoscope-assisted hairline approach. Oral Oncol. 2017;65:83-88 pubmed publisher
    ..However, such operations are not yet standard in submandibular gland (SMG) surgery due to the anatomic complexity of this region...
  63. Uchida H, Nakamura T, Takasu N, Obana Koshino A, Ono H, Todo T, et al. The central clock controls the daily rhythm of Aqp5 expression in salivary glands. J Physiol Sci. 2018;68:377-385 pubmed publisher
    ..In cultured SMGs ex vivo, clock genes showed distinct circadian rhythms, whereas Aqp5 expression did not. These data indicate that daily Aqp5 expression in the mouse SMG is driven by the central clock in the SCN.
  64. Shao M, Blechl A, Thomson J. Small serine recombination systems ParA-MRS and CinH-RS2 perform precise excision of plastid DNA. Plant Biotechnol J. 2017;15:1577-1589 pubmed publisher
    ..tools for site-specific manipulation of the plastid genome and for generating marker-free plants, an essential step for reuse of SMG and for addressing concerns about the presence of antibiotic resistance genes in transgenic plants.
  65. Miao P, Wang C, Li P, Wei S, Deng C, Zheng D, et al. Altered gray matter volume, cerebral blood flow and functional connectivity in chronic stroke patients. Neurosci Lett. 2018;662:331-338 pubmed publisher
    ..motor area (SMA), increased CBFs in contralesional superior frontal gyrus (SFG) and supramarginal gyrus (SMG) irrespective of GMV correction...
  66. Éva C, Téglás F, Zelenyánszki H, Tamas C, Juhász A, Mészáros K, et al. Cold inducible promoter driven Cre-lox system proved to be highly efficient for marker gene excision in transgenic barley. J Biotechnol. 2018;265:15-24 pubmed publisher
    A Cre-lox based auto-excision strategy has been adapted for barley, capable of cre and selectable marker gene (SMG) removal. The cold inducible wheat promoter called wcs120 was utilised for driving Cre expression...
  67. Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes?. Trends Cell Biol. 2004;14:226-32 pubmed
    ..We discuss how this surveillance capacity of the SMN complex might ensure assembly of Sm cores only on the correct RNAs and prevent illicit, potentially deleterious assembly of Sm cores on random RNAs. ..
  68. Kleibeuker S, Stevenson C, van der Aar L, Overgaauw S, van Duijvenvoorde A, Crone E. Training in the adolescent brain: An fMRI training study on divergent thinking. Dev Psychol. 2017;53:353-365 pubmed publisher
    ..of objects (control task condition) was associated with increased activation in the supramarginal gyrus (SMG), angular gyrus (AG), and middle temporal gyrus (MTG)...
  69. Leung A, Nagai K, Li J. Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis. Nature. 2011;473:536-9 pubmed publisher
    ..and U5 small nuclear ribonucleoproteins (snRNPs), contain seven Sm proteins (SmB/B', SmD1, SmD2, SmD3, SmE, SmF and SmG) in common...
  70. Eken A, Gokcay D, Yılmaz C, Baskak B, Baltacı A, Kara M. Association of Fine Motor Loss and Allodynia in Fibromyalgia: An fNIRS Study. J Mot Behav. 2017;:1-13 pubmed publisher
    ..HC showed higher activity than FM patients in bilateral superior parietal gyrus (SPG), left supramarginal gyrus (SMG) and right somatosensory cortex (SI)...
  71. Matsumoto S, Kurimoto T, Taketo M, Fujii S, Kikuchi A. The WNT/MYB pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation. Development. 2016;143:2311-24 pubmed publisher
    ..mice and organ cultures revealed that WNT signaling at an early stage (E12-E15) of submandibular salivary gland (SMG) development inhibits end bud morphogenesis and differentiation into proacini by suppressing Kit expression through ..
  72. Bradley J, Stein R, Randolph B, Molina E, Arnold J, Gregg R. T cell resistance to activation by dendritic cells requires long-term culture in simulated microgravity. Life Sci Space Res (Amst). 2017;15:55-61 pubmed publisher
    ..line, OT-II TCH, to activation by DC when the T cells were cultured 24-120 h in a simulated microgravity (SMG) environment generated by a rotary cell culture system...
  73. Króliczak G, Piper B, Frey S. Specialization of the left supramarginal gyrus for hand-independent praxis representation is not related to hand dominance. Neuropsychologia. 2016;93:501-512 pubmed publisher
    ..with significant, exclusively left-lateralized and extensive increases of activity in the supramarginal gyrus (SMg), and more focal modulations in the left caudal middle temporal gyrus (cMTg)...
  74. Randerath J, Valyear K, Philip B, Frey S. Contributions of the parietal cortex to increased efficiency of planning-based action selection. Neuropsychologia. 2017;105:135-143 pubmed publisher
    ..Results from prior studies implicate the left supramarginal gyrus (SMg), premotor and prefrontal cortices, as well as the cerebellum in this essential function...
  75. Pillai R, Will C, Luhrmann R, Schumperli D, Muller B. Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. EMBO J. 2001;20:5470-9 pubmed
    ..This novel type of Sm complex, composed of both conventional Sm proteins and the Sm-like Lsm10, is most likely to be important for U7 snRNP function and subcellular localization. ..
  76. Chari A, Golas M, Klingenhäger M, Neuenkirchen N, Sander B, Englbrecht C, et al. An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. Cell. 2008;135:497-509 pubmed publisher
    ..The mode of action of this combined chaperone/catalyst system is reminiscent of the mechanism employed by DNA clamp loaders. ..
  77. Hovland E, Beyene G, Frye S, Homberset H, Balasingham S, Gómez Muñoz M, et al. DprA from Neisseria meningitidis: properties and role in natural competence for transformation. Microbiology. 2017;163:1016-1029 pubmed publisher
    ..dprA is co-expressed with smg, a downstream gene of unknown function, and the gene encoding topoisomerase 1, topA.
  78. Zeng W, Lee M, Yan M, Diaz J, Benjamin I, Marino C, et al. Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells. Am J Physiol. 1997;273:C442-55 pubmed
    ..and functional evidence for expression of CFTR protein and Cl- current in rat and mouse submandibular gland (SMG) and pancreatic acinar cells, a site proximal to the ductal system of these secretory glands...
  79. Kim Y, Kwon H, Shinozaki N, Hashimoto S, Shimono M, Cho S, et al. Comparative analysis of ABCG2-expressing and label-retaining cells in mouse submandibular gland. Cell Tissue Res. 2008;334:47-53 pubmed publisher
    The submandibular gland (SMG) is a tissue that can be regenerated in a tissue injury model and that has adult stem cells capable of self-renewal and differentiation into functional cells...
  80. Buravkova L, Rudimov E, Andreeva E, Grigoriev A. The ICAM-1 expression level determines the susceptibility of human endothelial cells to simulated microgravity. J Cell Biochem. 2017;: pubmed publisher
    ..VE-cadherin) in umbilical cord endothelial cells (ECs) after 24?h of exposure to simulated microgravity (SMG), pro-inflammatory cytokine TNF-?, and the combination of the two...
  81. Lynch T, Anderson P, Xie W, Crooke A, Liu X, Tyler S, et al. Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands. Stem Cells. 2016;34:2758-2771 pubmed publisher
    Wnt signaling is required for lineage commitment of glandular stem cells (SCs) during tracheal submucosal gland (SMG) morphogenesis from the surface airway epithelium (SAE)...
  82. Okada Katsuhata Y, Yamashita A, Kutsuzawa K, Izumi N, Hirahara F, Ohno S. N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD. Nucleic Acids Res. 2012;40:1251-66 pubmed publisher
    ..b>SMG-1-mediated Upf1 phosphorylation takes place in the decay inducing complex (DECID), which contains a ribosome, ..
  83. Weiss Y, Katzir T, Bitan T. When transparency is opaque: Effects of diacritic marks and vowel letters on dyslexic Hebrew readers. Cortex. 2016;83:145-59 pubmed publisher
    ..Dyslexic readers demonstrated reduced activation in left supramarginal gyrus (SMG) as compared to typical readers, as well as different patterns of activation within the left inferior frontal gyrus ..
  84. Almansoori A, Khentii N, Hei W, Seo N, Lee S, Kim S, et al. Rabbit submandibular salivary gland replantation. J Korean Assoc Oral Maxillofac Surg. 2017;43:299-304 pubmed publisher
    To test the feasibility of submandibular salivary gland (SMG) replantation techniques and the survival of the replanted glands...
  85. Page M, Carr B, Anders K, Grimson A, Anderson P. SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol Cell Biol. 1999;19:5943-51 pubmed
    ..Mutations affecting three yeast UPF genes or seven nematode smg genes eliminate NMD. We report here the molecular analysis of smg-2 of Caenorhabditis elegans...
  86. Serin G, Gersappe A, Black J, Aronoff R, Maquat L. Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4). Mol Cell Biol. 2001;21:209-23 pubmed
    ..Here, we describe human orthologues to S. cerevisiae Upf2p and S. cerevisiae Upf3p (Caenorhabditis elegans SMG-4) based on limited amino acid similarities...
  87. Muir V, Gasch A, Anderson P. The Substrates of Nonsense-Mediated mRNA Decay in Caenorhabditis elegans. G3 (Bethesda). 2018;8:195-205 pubmed publisher
    ..We previously demonstrated that Upf1p/SMG-2, the central effector of NMD in all studied eukaryotes, preferentially associates with mRNAs that contain ..
  88. Takahashi D, Suzuki H, Kakei Y, Yamakoshi K, Minami Y, Komori T, et al. Expression of Ror2 associated with fibrosis of the submandibular gland. Cell Struct Funct. 2017;: pubmed publisher
    The submandibular gland (SMG) is one of the major salivary glands that play important roles for variety of physiological functions, such as digestion of foods, prevention of infection, and lubrication of the mouth...
  89. Zhang R, So B, Li P, Yong J, Glisovic T, Wan L, et al. Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly. Cell. 2011;146:384-95 pubmed publisher
    ..These findings provide insight into SMN complex assembly and specificity, linking snRNP biogenesis and SMA pathogenesis. ..
  90. Gonzalez Huici V, Wang B, Gartner A. A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans. Genetics. 2017;206:1853-1864 pubmed publisher
    ..We have performed an unbiased genetic screen, finding that smg-1 mutations confer strong hyper-sensitivity to IR...
  91. Felle M, Joppien S, Nemeth A, Diermeier S, Thalhammer V, Dobner T, et al. The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1. Nucleic Acids Res. 2011;39:8355-65 pubmed publisher
    ..Therefore, we propose a dual role of USP7, regulating the protein turnover of UHRF1 and stimulating the enzymatic activity of Dnmt1 in vitro and in vivo. ..
  92. Wang H, Chen T, Ye L, Yang Q, Wei R, Zhang Y, et al. Network centrality in patients with acute unilateral open globe injury: A voxel?wise degree centrality study. Mol Med Rep. 2017;16:8295-8300 pubmed publisher
    ..decreased DC values in the right insula, left insula, right inferior parietal lobule (IPL)/supramarginal gyrus (SMG), IPL/SMG, right supplementary motor area and right postcentral gyrus...