SLC25A4

Summary

Gene Symbol: SLC25A4
Description: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Alias: AAC1, ANT, ANT 1, ANT1, MTDPS12, PEO2, PEO3, ADP,ATP carrier protein 1, ADP,ATP carrier protein, heart/skeletal muscle, ADP/ATP translocase 1, adenine nucleotide translocator 1 (skeletal muscle), heart/skeletal muscle ATP/ADP translocator, solute carrier family 25 member 4
Species: human

Top Publications

  1. ncbi A comparative analysis of morphological and ecological characters of European aphids and lycaenids in relation to ant attendance
    Bernhard Stadler
    Bayreuth Institute for Terrestrial Ecosystem Research, University of Bayreuth, 95440, Bayreuth, Germany
    Oecologia 135:422-30. 2003
  2. ncbi Correlation between expression of cyclooxygenase-2 and the presence of CD4+ infiltrating T-lymphocyte in human primary hepatocellular carcinoma
    Ya Wei Gao
    Department of Immunology, Xiangya School of Medicine, Central South University, Changsha, PR China
    Hepatogastroenterology 55:345-50. 2008
  3. pmc Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2
    E Jacotot
    Centre National de la Recherche Scientifique, UMR 1599, Institut Gustave Roussy, F 94805 Villejuif, France
    J Exp Med 193:509-19. 2001
  4. ncbi Increased levels of adenine nucleotide translocator 1 protein and response to oxidative stress are early events in facioscapulohumeral muscular dystrophy muscle
    Dalila Laoudj-Chenivesse
    Centre de Recherche en Biochimie et Macromoléculaire, FRE 2593 CNRS, 1919 Route de Mende, 34293, Montpellier Cedex 5, France
    J Mol Med (Berl) 83:216-24. 2005
  5. ncbi Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
    I Marzo
    CNRS, UPR 420, 19 rue Guy Moquet, F 94801 Villejuif, France
    Science 281:2027-31. 1998
  6. ncbi Mitochondrial control of cell death induced by HIV-1-encoded proteins
    K F Ferri
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Ann N Y Acad Sci 926:149-64. 2000
  7. pmc The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
    E Jacotot
    Centre National de la Recherche Scientifique, F 94801 Villejuif, France
    J Exp Med 191:33-46. 2000
  8. pmc Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
    Julian J Lum
    Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    J Clin Invest 111:1547-54. 2003
  9. ncbi Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore
    M Crompton
    Department of Biochemistry and Molecular Biology, University College London, UK
    Eur J Biochem 258:729-35. 1998
  10. ncbi [Mediators of the vascular endothelium as markers of myocardial ischemia and reperfusion]
    D Jambou
    Service de cardiologie, , Nice
    Arch Mal Coeur Vaiss 86:57-62. 1993

Detail Information

Publications242 found, 100 shown here

  1. ncbi A comparative analysis of morphological and ecological characters of European aphids and lycaenids in relation to ant attendance
    Bernhard Stadler
    Bayreuth Institute for Terrestrial Ecosystem Research, University of Bayreuth, 95440, Bayreuth, Germany
    Oecologia 135:422-30. 2003
    ..ants and aphids/lycaenids and (2) contrast different taxonomic levels with respect to the variance explained by ant attendance...
  2. ncbi Correlation between expression of cyclooxygenase-2 and the presence of CD4+ infiltrating T-lymphocyte in human primary hepatocellular carcinoma
    Ya Wei Gao
    Department of Immunology, Xiangya School of Medicine, Central South University, Changsha, PR China
    Hepatogastroenterology 55:345-50. 2008
    ..the relationship among Cox-2, CD4+ TIL of tumor and CD4+ infiltrating T-lymphocytes of adjoining non-tumorous (ANT) tissues in tumor-microenvironment...
  3. pmc Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2
    E Jacotot
    Centre National de la Recherche Scientifique, UMR 1599, Institut Gustave Roussy, F 94805 Villejuif, France
    J Exp Med 193:509-19. 2001
    ..the voltage-dependent anion channel (VDAC) in the outer membrane (OM) and the adenine nucleotide translocator (ANT) in the inner membrane...
  4. ncbi Increased levels of adenine nucleotide translocator 1 protein and response to oxidative stress are early events in facioscapulohumeral muscular dystrophy muscle
    Dalila Laoudj-Chenivesse
    Centre de Recherche en Biochimie et Macromoléculaire, FRE 2593 CNRS, 1919 Route de Mende, 34293, Montpellier Cedex 5, France
    J Mol Med (Berl) 83:216-24. 2005
    ..any of the 4q35 genes, among which is the heart and muscle-specific isoform of the adenine nucleotide translocator (ANT1)...
  5. ncbi Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
    I Marzo
    CNRS, UPR 420, 19 rue Guy Moquet, F 94801 Villejuif, France
    Science 281:2027-31. 1998
    ..permeabilize membranes in response to atractyloside, a proapoptotic ligand of the adenine nucleotide translocator (ANT). Bax and ANT coimmunoprecipitated and interacted in the yeast two-hybrid system...
  6. ncbi Mitochondrial control of cell death induced by HIV-1-encoded proteins
    K F Ferri
    Centre National de la Recherche Scientifique, UMR1599, Institut Gustave Roussy, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Ann N Y Acad Sci 926:149-64. 2000
    ..Vpr exemplifies a direct MMP inducer. Vpr binds to the adenine nucleotide translocator (ANT), a mitochondrial inner membrane protein which also interacts with apoptosis-regulatory proteins from the Bcl-2/Bax ..
  7. pmc The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
    E Jacotot
    Centre National de la Recherche Scientifique, F 94801 Villejuif, France
    J Exp Med 191:33-46. 2000
    ..membranes containing the purified PTPC or defined PTPC components such as the adenine nucleotide translocator (ANT) combined with Bax. Again, this effect is prevented by addition of recombinant Bcl-2...
  8. pmc Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
    Julian J Lum
    Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    J Clin Invest 111:1547-54. 2003
    ..These data highlight the pathophysiologic role of Vpr in HIV-induced immune disease and suggest a novel mechanism of LTNP...
  9. ncbi Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore
    M Crompton
    Department of Biochemistry and Molecular Biology, University College London, UK
    Eur J Biochem 258:729-35. 1998
    ....
  10. ncbi [Mediators of the vascular endothelium as markers of myocardial ischemia and reperfusion]
    D Jambou
    Service de cardiologie, , Nice
    Arch Mal Coeur Vaiss 86:57-62. 1993
    ..relaxing factors" (EDRFs) nitrous oxide, prostacyclin, which are vasodilators and platelet antiaggregants ant the "endothelium-derived contracting factors" (EDCFs), endothelin, PGH2, oxygen-free radicals which are ..
  11. ncbi Genomic characterization of Tv-ant-1, a Caenorhabditis elegans tag-61 homologue from the parasitic nematode Trichostrongylus vitrinus
    Min Hu
    Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
    Gene 397:12-25. 2007
    A full-length cDNA (Tv-ant-1) encoding an adenine nucleotide translocator (ANT or ADP/ATP translocase) (Tv-ANT-1) was isolated from Trichostrongylus vitrinus (order Strongylida), an economically important parasitic nematode of small ..
  12. ncbi The adenine nucleotide translocase type 1 (ANT1): a new factor in mitochondrial disease
    J Daniel Sharer
    Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    IUBMB Life 57:607-14. 2005
    ..are associated with dysfunction of the heart and muscle-specific isoform of the adenine nucleotide translocase (ANT1), a nDNA gene product that facilitates transport of ATP and ADP across the inner mitochondrial membrane...
  13. ncbi [Characteristics of adenine nucleotide translocator in mitochondria of rat cerebral cortex during hypobaric hypoxia exposure.]
    Li Fen Chen
    Department of Pathophysiology, College of High Altitude Military Medicine, The Third Military Medical University, Chongqing 400038, China
    Sheng Li Xue Bao 58:29-33. 2006
    ..the present study was to explore the effects of hypoxic exposure on mitochondrial adenine nucleotide translocator (ANT) activity and its characteristics...
  14. doi Isolation, nucleotide identification and tissue expression of three novel ovine genes-SLC25A4, SLC25A5 and SLC25A6
    Liangyu Yang
    Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China
    Mol Biol Rep 37:2743-8. 2010
    The complete coding sequences of three of sheep genes SLC25A4, SLC25A5 and SLC25A6 were firstly amplified using the reverse transcriptase polymerase chain reaction (RT-PCR) according to the conserved sequence information of the cattle or ..
  15. pmc Dominant membrane uncoupling by mutant adenine nucleotide translocase in mitochondrial diseases
    Xiaowen Wang
    Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York, NY 13210, USA
    Hum Mol Genet 17:4036-44. 2008
    ..Ant also possesses a discrete membrane uncoupling activity. Specific mis-sense mutations in the human Ant1 cause autosomal dominant Progressive External Ophthalmoplegia (adPEO), mitochondrial myopathy and cardiomyopathy, ..
  16. doi Fatal anaphylaxis to indoor native fire ant stings in an infant
    Daniel R More
    Department of Allergy and Immunology, Luke AFB, Arizona 85309, USA
    Am J Forensic Med Pathol 29:62-3. 2008
    ..The following is a report of fatal anaphylaxis to a native fire ant sting in an infant that occurred indoors at a daycare facility. A 3-month-old female was left unattended on a bed...
  17. ncbi [Effects of gonadotropin releasing hormone analogues on chemotherapy-induced ovarian function damage in rats]
    Ping Peng
    Department of Obstetrics and Gynecology, Second Affiliated Hospital, Sun Yat Sen University, Guangzhou 510120, China
    Zhonghua Fu Chan Ke Za Zhi 42:546-50. 2007
    To investigate the effects of gonadotropin releasing hormone agonist (GnRH-a) and antagonist (GnRH-ant) on cyclophosphamide (CTX)-induced ovarian damage in rats.
  18. pmc TGF-beta1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors
    Alick K T Law
    Department of Physiology, Emory University, Atlanta, USA
    BMC Neurosci 5:1. 2004
    The adenine nucleotide translocator 1 (Ant1) is an inner mitochondrial membrane protein involved with energy mobilization during oxidative phosphorylation...
  19. ncbi Look before leaping: foraging selectivity of capuchin monkeys on acacia trees in Costa Rica
    Hilary Young
    Department of Biological Sciences, University of Calgary, T2N IN4 Calgary, AB, Canada
    Oecologia 155:85-92. 2008
    ..Depending on the size and species of ant colony, individual acacia trees may be differentially protected...
  20. ncbi [Ant venoms: a rare cause of allergic reactions in Switzerland]
    J D Seebach
    Departement fur Innere Medizin, Medizinische Klinik A, Universitatsspital, Ramistrasse 100, C HOER 31 CH 8091 Zürich
    Schweiz Med Wochenschr 130:1805-13. 2000
    ..several patients with sensitisation or allergy to the venom of imported fire ants (Solenopsis), a species of ant found in the Americas...
  21. ncbi Effects of oil pollution at Kuwait's greater Al-Burgan oil field on polycyclic aromatic hydrocarbon concentrations in the tissues of the desert lizard Acanthodactylus scutellatus and their ant prey
    Mona A Al-Hashem
    Department of Biological Sciences, Kuwait University, Safat, State of Kuwait
    Ecotoxicology 16:551-5. 2007
    ..Ants from the same sites were also collected and treated in a similar manner. Lizard and ant whole body tissues were subjected to gas chromatography-mass spectrometry (GC-MS) to determine concentrations of ..
  22. pmc Adenine nucleotide translocator 1 deficiency increases resistance of mouse brain and neurons to excitotoxic insults
    Jaewon Lee
    Center for Molecular and Mitochondrial Medicine and Genetics, University of California, Irvine, CA 92697 3940, USA
    Biochim Biophys Acta 1787:364-70. 2009
    ..The mouse has three Ant isoforms: Ant1 expressed in heart, muscle, and brain; Ant2 expressed in all tissues but muscle; and Ant4 expressed primarily in ..
  23. pmc MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: coordinate regulation of OXPHOS, antioxidant, and apoptotic genes
    Vaidya Subramaniam
    Center of Molecular and Mitochondrial Medicine and Genetics MAMMAG and Department of Biological Chemistry, University of California Irvine, 2010 Hewitt Hall, Irvine, CA 92697, USA
    Biochim Biophys Acta 1777:666-75. 2008
    Genetic inactivation of the nuclear-encoded mitochondrial heart-muscle adenine nucleotide translocator-1 (ANT1), which exports mitochondrial ATP to the cytosol in both humans (ANT1-/-) and mice (Ant1-/-), results in lactic acidosis and ..
  24. ncbi Leptin and thyroxine during sexual development in male monkeys: effect of neonatal gonadotropin-releasing hormone antagonist treatment and delayed puberty on the developmental pattern of leptin and thyroxine secretion
    D R Mann
    Department of Physiology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Eur J Endocrinol 146:891-8. 2002
    Neonatal treatment of male monkeys with a gonadotropin-releasing hormone antagonist (Ant) increased the incidence of delayed puberty...
  25. ncbi [Exploration of left ventricular relaxation using gamma-angiography in 70 hypertensive subjects. Practical consequences and implications]
    J P Ollivier
    , Paris
    Arch Mal Coeur Vaiss 82:1109-14. 1989
    This study was performed to evaluate the incidence ant the practical consequences of left ventricular diastolic dysfunction in hypertensive...
  26. ncbi The origin of the attine ant-fungus mutualism
    U G Mueller
    Section of Integrative Biology, Patterson Laboratories, University of Texas, Austin, TX 78712, USA
    Q Rev Biol 76:169-97. 2001
    ..1894), in rotting wood (Forel 1902), as mycorrhizae (Garling 1979), on arthropod corpses (von Ihering 1894) or ant faeces in nest middens (Wheeler 1907)...
  27. ncbi Effects of large mammalian herbivores and ant symbionts on condensed tannins of Acacia drepanolobium in Kenya
    David Ward
    Mitrani Department for Desert Ecology and Ramon Science Centre, Ben Gurion University of the Negev, Sede Boqer, Israel
    J Chem Ecol 28:921-37. 2002
    ..total exclusion, antelope only, and megaherbivore (elephants and giraffes) + antelope] and with four different ant symbiont species on the trees...
  28. pmc Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells
    Ziqiang Yang
    National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, China
    Mol Biol Cell 18:4681-9. 2007
    Mitochondrial adenine nucleotide translocase (ANT) is believed to be a component or a regulatory component of the mitochondrial permeability transition pore (mtPTP), which controls mitochondrial permeability transition during apoptosis...
  29. pmc Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion
    Daniela Centron
    Departement de Biochimie et de Microbiologie, Faculte des sciences et de genie, Universite Laval, Sainte Foy, Quebec, Canada G1K 7P4
    Antimicrob Agents Chemother 46:1402-9. 2002
    ..By PCR, hybridization, and sequencing analyses, we found that integron 1 has the dfrA1 and ant(3")-Ia cassettes...
  30. ncbi Ant behaviour and seed morphology: a missing link of myrmecochory
    Crisanto Gómez
    Departament de Ciències Ambientals, Universitat de Girona, 17071 Girona, Spain
    Oecologia 146:244-6. 2005
    ..When seeds mature or fall onto the ground, these ant species transport them to their nest...
  31. ncbi Diminished cardioprotective response to inhibition of angiotensin-converting enzyme and angiotensin II type 1 receptor in B(2) kinin receptor gene knockout mice
    X P Yang
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
    Circ Res 88:1072-9. 2001
    ..effect of angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II type 1 receptor antagonists (AT(1)-ant), whereas lack of B(2) receptors may diminish this cardioprotective effect...
  32. ncbi Aggressive interactions between Solenopsis invicta and Linepithema humile (Hymenoptera: Formicidae) under laboratory conditions
    J N Kabashima
    University of California Cooperative Extension Orange County, 1045 Arlington Dr, Gate 4, Costa Mesa, CA 92626, USA
    J Econ Entomol 100:148-54. 2007
    The Argentine ant, Linepithema humile (Mayr), and the red imported fire ant, Solenopsis invicta Buren, are natural agonists in their country of origin. Since the first report of L...
  33. doi Compatibility of imported fire ant whole body extract with cat, ragweed, Dermatophagoides pteronyssinus, and timothy grass allergens
    Tonya S Rans
    Department of Allergy and Immunology, Wilford Hall Medical Center, San Antonio, Texas 78236, USA
    Ann Allergy Asthma Immunol 102:57-61. 2009
    Recommendations regarding the administration of imported fire ant whole body extract (IFA WBE) combined with aeroallergens or environmental allergens in a single immunotherapy injection are lacking.
  34. ncbi Hormone responses to sedative drugs and cold exposure in two rat lines with high and low alcohol sensitivity
    E R Korpi
    Research Laboratories, Alko Ltd, Helsinki, Finland
    Pharmacol Biochem Behav 41:795-9. 1992
    ..The alcohol-sensitive ANT rats had significantly lower plasma corticosterone concentrations than the alcohol-insensitive AT rats 30 min after ..
  35. ncbi The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death
    Andrew P Halestrap
    Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
    Curr Med Chem 10:1507-25. 2003
    In addition to its normal function, the adenine nucleotide translocase (ANT) forms the inner membrane channel of the mitochondrial permeability transition pore (MPTP)...
  36. ncbi Eliminating the Ant1 isoform produces a mouse with CPEO pathology but normal ocular motility
    Hang Yin
    Atlanta VA Medical Center, Decatur, Georgia 30033, USA
    Invest Ophthalmol Vis Sci 46:4555-62. 2005
    The adenine nucleotide transporter 1 gene (ANT1) encodes an inner mitochondrial membrane protein that transports ATP into the cell. Mutations within ANT1 produce a syndrome of chronic progressive external ophthalmoplegia (CPEO) in humans...
  37. doi Biodiversity loss in Latin American coffee landscapes: review of the evidence on ants, birds, and trees
    Stacy M Philpott
    Smithsonian Migratory Bird Center, Washington, DC 20013, USA
    Conserv Biol 22:1093-1105. 2008
    ..We quantitatively reviewed data from ant, bird, and tree biodiversity studies in coffee agroecosystems to address the following questions: Does species ..
  38. doi Impact of adenosine nucleotide translocase (ANT) proline isomerization on Ca2+-induced cysteine relative mobility/mitochondrial permeability transition pore
    Cezar R Pestana
    Departamento de Fisica e Quimica, Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, SP, Brazil
    J Bioenerg Biomembr 42:329-35. 2010
    Mitochondrial membrane carriers containing proline and cysteine, such as adenine nucleotide translocase (ANT), are potential targets of cyclophilin D (CyP-D) and potential Ca(2+)-induced permeability transition pore (PTP) components or ..
  39. doi The interaction between Cistaceae and a highly specific seed-harvester ant in a Mediterranean scrubland
    F Bastida
    Departamento de Ciencias Agroforestales, Universidad de Huelva, Huelva, Spain
    Plant Biol (Stuttg) 11:46-56. 2009
    We studied the interaction between the ant Goniomma kugleri and Cistaceae in a Cistus ladanifer-dominated scrubland, in southwestern Spain...
  40. pmc Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively
    Irina G Shabalina
    The Wenner Gren Institute, The Arrhenius Laboratories F3, Stockholm University, SE 106 91 Stockholm, Sweden
    Biochem J 399:405-14. 2006
    ..However, in liver, only Ant2 mRNA was found, whereas in brown adipose tissue, Ant1 and Ant2 mRNA levels were equal...
  41. ncbi Catching ants with honey: an experimental test of distraction and satiation as alternative modes of escape from flower-damaging ants
    Candace Galen
    Division of Biological Sciences, University of Missouri, 105 Tucker Hall, Columbia, MO 65211 7400, USA
    Oecologia 144:80-7. 2005
    ..hypothesis, extrafloral nectaries (EFN) evolved under selection to entice ants away from floral nectaries, reducing ant-mediated damage to flowers and/or interference with pollinators...
  42. pmc Wolbachia transmission dynamics in Formica wood ants
    Lumi Viljakainen
    Department of Biology, PO Box 3000, 90014 University of Oulu, Finland
    BMC Evol Biol 8:55. 2008
    ..compared the sequence diversity of wsp (Wolbachia surface protein gene) and the host mtDNA in a group of Formica ant species that have diverged approximately 0.5 million years ago (MYA)...
  43. doi The role of extrafloral nectar amino acids for the preferences of facultative and obligate ant mutualists
    Marcia González-Teuber
    Department of General Botany Plant Ecology, University of Duisburg Essen, Essen, Germany
    J Chem Ecol 35:459-68. 2009
    ..Among Mesoamerican Acacia species, obligate myrmecophytes produce EFN constitutively to nourish symbiotic ant mutualists, while non-myrmecophytes induce EFN secretion in response to herbivore damage to attract non-symbiotic ..
  44. doi Changes in monoterpene emission rates of Quercus ilex infested by aphids tended by native or invasive Lasius ant species
    Carolina I Paris
    Department of Animal Biology, Plant Biology and Ecology, Autonomous University of Barcelona, Edifici C, Campus de Bellaterra UAB, Cerdanyola del Vallès Bellaterra, 08193, Barcelona, Spain
    J Chem Ecol 36:689-98. 2010
    ..The effect of Lachnus roboris aphids and two different tending ant species on terpene emission rates of 4-year-old holm oak (Quercus ilex) saplings was investigated during a field ..
  45. doi Stability of Myrmecia pilosula (Jack Jumper) Ant venom for use in immunotherapy
    Michael D Wiese
    School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, South Australia 5001, Australia
    J Pharm Biomed Anal 54:303-10. 2011
    Allergy to Myrmecia pilosula (Jack Jumper Ant) venom is common in Australia, affecting ∼2.7% of some communities...
  46. ncbi Ectopic expression of the human adenine nucleotide translocase, isoform 3 (ANT-3). Characterization of ligand binding properties
    A K Carroll
    MitoKor, Inc, San Diego, CA 92121, USA
    Mitochondrion 5:1-13. 2005
    The adenine nucleotide translocase (ANT) is a key component in maintaining cellular energy homeostasis, and has also been implicated in formation of the mitochondrial permeability transition pore...
  47. ncbi The effect of anthracene and phenanthrene on the growth, photosynthesis, and SOD activity of the green alga Scenedesmus armatus depends on the PAR irradiance and CO2 level
    A Aksmann
    Department of Plant Physiology, University of Gdansk, al MarszaŁka PiŁsudskiego 46, 81 378 Gdynia, Poland
    Arch Environ Contam Toxicol 47:177-84. 2004
    Short-term (24-h) experiments were performed to examine the effect of phenanthrene (PHE) and anthracene (ANT) on algae grown in a batch culture system at irradiances of 12, 33, 48, and 64 W m(-2) of the PAR range...
  48. ncbi Use of antibiotics and roxarsone in broiler chickens in the USA: analysis for the years 1995 to 2000
    H D Chapman
    Department of Poultry Science, University of Arkansas, Fayetteville 72701, USA
    Poult Sci 81:356-64. 2002
    In 1995, an antibiotic (ANT) was used in starter, grower, and withdrawal (WD) feeds by 94.3, 98.2, and 75.1% of broiler production units, but by 2000, ANT use had declined to 64.8, 66.9, and 48.1% respectively...
  49. doi Ca(2+) binding to c-state of adenine nucleotide translocase (ANT)-surrounding cardiolipins enhances (ANT)-Cys(56) relative mobility: a computational-based mitochondrial permeability transition study
    Cezar R Pestana
    Departamento de Fisica e Quimica, Toxicologicas e Bromatologicas, Universidade de Sao Paulo, 14040 903 Ribeirão Preto SP, Brazil
    Biochim Biophys Acta 1787:176-82. 2009
    The oxidation of critical cysteines/related thiols of adenine nucleotide translocase (ANT) is believed to be an important event of the Ca(2+)-induced mitochondrial permeability transition (MPT), a process mediated by a cyclosporine A/ADP-..
  50. ncbi Inhibition of ovulation in the rat by a leukotriene B(4) receptor antagonist
    M Matousek
    Department of Obstetrics and Gynecology, Goteborg University, Goteborg, Sweden
    Mol Hum Reprod 7:35-42. 2001
    ..B(4) in the ovulatory process of the rat was investigated by the use of a LTB(4)-receptor antagonist (ZK158252 = L-ANT) administered either intrabursally in vivo or to the in-vitro perfused ovary...
  51. doi NMR-based analysis of aminoglycoside recognition by the resistance enzyme ANT(4'): the pattern of OH/NH3(+) substitution determines the preferred antibiotic binding mode and is critical for drug inactivation
    Julia Revuelta
    Instituto de Química Orgánica general CSIC, Madrid 28006, Spain
    J Am Chem Soc 130:5086-103. 2008
    ..Herein, we analyze several key aspects of the aminoglycoside recognition by the resistance enzyme ANT(4') from Staphylococcus aureus, employing NMR complemented with site-directed mutagenesis experiments and ..
  52. ncbi Cloning of two pectate lyase genes from the marine Antarctic bacterium Pseudoalteromonas haloplanktis strain ANT/505 and characterization of the enzymes
    L V Truong
    Institute of Biotechnology, National Center of Natural Science and Technology, Tu Liem, Hanoi, Vietnam
    Extremophiles 5:35-44. 2001
    A marine Antarctic psychrotolerant bacterium (strain ANT/505), isolated from sea ice-covered surface water from the Southern Ocean, showed pectinolytic activity on citrus pectin agar...
  53. ncbi Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease
    Thomas Walther
    Charite Universitatsmedizin, Campus Benjamin Franklin, Department of Cardiology and Pneumonology, Hindenburgdamm 30, 12200 Berlin, Germany
    Circulation 115:333-44. 2007
    ..An adequate exchange of ATP and ADP over the inner mitochondrial membrane by the adenine nucleotide translocase (ANT) is thereby essential to guarantee the cellular energy supply.
  54. ncbi Thermal ecology of the neotropical army ant Eciton burchellii
    Joe E Meisel
    Department of Zoology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Ecol Appl 16:913-22. 2006
    I explored the thermal ecology of Eciton burchellii, a New World army ant, in primary forest and forest fragments in the Atlantic lowlands of Costa Rica in 2002 and 2003...
  55. doi Plant genotype shapes ant-aphid interactions: implications for community structure and indirect plant defense
    Kailen A Mooney
    Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92697, USA
    Am Nat 171:E195-205. 2008
    ..Populations of the ant-tended aphid Aphis asclepiadis and the untended aphid Myzocallis asclepiadis varied eight- to 18-fold among ..
  56. pmc Ant mimicry by an aphid parasitoid, Lysiphlebus fabarum
    Arash Rasekh
    Department of Plant Protection, College of Agriculture, University of Tehran, Karaj, Iran
    J Insect Sci 10:126. 2010
    ..Aphis fabae Scopoli (Hemiptera: Aphididae), that possesses various highly evolved adaptations for foraging within ant-tended aphid colonies...
  57. doi Trade-offs underlying polyphagy in a facultative ant-tended florivorous butterfly: the role of host plant quality and enemy-free space
    Daniela Rodrigues
    Departamento de Biologia Animal, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, SP, Brazil
    Oecologia 163:719-28. 2010
    ..Plant traits such as presence of ant-treehopper associations as a source of enemy-free space, flower bud dimensions, toughness, thickness, trichomes, ..
  58. ncbi Myrmecia pilosula (Jack Jumper) ant venom: identification of allergens and revised nomenclature
    M D Wiese
    Department of Pharmacy, Royal Hobart Hospital, Hobart, Tasmania, Australia
    Allergy 62:437-43. 2007
    The 'Jack Jumper Ant' (JJA; Myrmecia pilosula species complex) is the major cause of ant sting anaphylaxis in Australia...
  59. ncbi [Restless legs syndrome and periodic leg movements during sleep in patients with sleep apnea--a therapeutic problem?]
    P Dorow
    Medizinische Klinik I, Humboldt Universitat zu Berlin
    Pneumologie 51:716-20. 1997
    ..Simultaneous videorecordings and EMG of mm. tibialis ant. ensure diagnosis. Therapeutic regime may be difficult due to failure or side effects, however...
  60. doi Enhancement of fibrinolytic activity in vascular endothelial cells by heterologous expression of adenine nucleotide translocase-1
    Chikako Ishida
    Department of Physiology, Kinki University School of Medicine, Ohno Higashi, Osakasayama, Osaka, Japan
    Blood Coagul Fibrinolysis 21:272-8. 2010
    ..Its amino acid sequence has matched that of human adenine nucleotide translocase-1 (ANT1)...
  61. ncbi The congenital "ant-egg" cataract phenotype is caused by a missense mutation in connexin46
    Lars Hansen
    The Wilhelm Johannsen Centre for Functional Genome Research, Institute of Medical Biochemistry and Genetics, University of Copenhagen, Copenhagen, Denmark
    Mol Vis 12:1033-9. 2006
    b>Ant-egg" cataract is a rare, distinct variety of congenital/infantile cataract that was reported in a large Danish family in 1967...
  62. pmc The evolution of genome size in ants
    Neil D Tsutsui
    Department of Environmental Science, Policy and Management, University of California Berkeley, Berkeley, CA 94720, USA
    BMC Evol Biol 8:64. 2008
    ..is a useful and necessary prerequisite for the development of many genomic resources, yet it has been reported for only one ant species (Solenopsis invicta), and the two published estimates for this species differ by 146.7 Mb (0.15 pg).
  63. ncbi Fire ant-detecting canines: a complementary method in detecting red imported fire ants
    Hui Min Lin
    Institute of Physics, Academia Sinica, Taipei, 128 Sec 2, Academia Rd, Nankang, 11592, Taiwan
    J Econ Entomol 104:225-31. 2011
    ..The methodology could assist in reducing the frequency and scope of chemical treatments for red imported fire ant management and thus reduce labor costs and chemical use as well as improve control and quarantine efficiency...
  64. pmc Preparation and biological evaluation of 64Cu-CB-TE2A-sst2-ANT, a somatostatin antagonist for PET imaging of somatostatin receptor-positive tumors
    Thaddeus J Wadas
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA
    J Nucl Med 49:1819-27. 2008
    Recently, the somatostatin receptor subtype 2 (SSTR2) selective antagonist sst2-ANT was determined to have a high affinity for SSTR2...
  65. ncbi Preference of food particle size among several urban ant species
    Linda M Hooper-Bùi
    Department of Entomology, Louisiana State University, Baton Rouge, LA 70803, USA
    J Econ Entomol 95:1222-8. 2002
    Appropriate particle size may be a critical characteristic for effective granular ant baits. We examined the particle size preference of six species of pest ants to an anchovy-based bait...
  66. ncbi [Analysis on 168 rRNA methylase genes and aminoglycoside modifying enzymes genes in Enterobacter cloacae in China]
    Zhi Mi Huang
    Microbiology Laboratory, 98th Hospital of People s Liberation Army, Huzhou 313000, China
    Zhonghua Liu Xing Bing Xue Za Zhi 29:369-73. 2008
    ..To investigate the 16S rRNA methylase genes and Aminoglycoside modifying enzymes (AMEs) genes in Enterobacter cloacae isolated from the People's Liberation Army 98th Hospital, Huzhou district, Zhejiang province, China...
  67. ncbi Effects of habitat fragmentation and degradation on flocks of African ant-following birds
    Marcell K Peters
    Zoologisches Forschungsmuseum A Koenig, Adenauerallee 160, D 53113 Bonn, Germany
    Ecol Appl 18:847-58. 2008
    ..neglected) ecological phenomena in African rain forests is the interaction between swarm-raiding army ants and ant-following birds...
  68. ncbi Habitat complexity facilitates coexistence in a tropical ant community
    M Sarty
    School of Biological Sciences, Victoria University of Wellington, P O Box 600, Wellington, New Zealand
    Oecologia 149:465-73. 2006
    The role of habitat complexity in the coexistence of ant species is poorly understood. Here, we examine the influence of habitat complexity on coexistence patterns in ant communities of the remote Pacific atoll of Tokelau...
  69. pmc Evolutionary history of Wolbachia infections in the fire ant Solenopsis invicta
    Michael E Ahrens
    Department of Entomology, 643 Russell Labs, 1630 Linden Drive, University of Wisconsin, Madison, WI 53706 USA
    BMC Evol Biol 5:35. 2005
    ..Wolbachia genome infecting 138 individuals from eleven geographically distributed native populations of the fire ant Solenopsis invicta...
  70. ncbi Imported fire ant stings: clinical manifestations and treatment
    P R Cohen
    Department of Dermatology, University of Texas Medical School, Houston 77030
    Pediatr Dermatol 9:44-8. 1992
    ..child developed a characteristic localized cutaneous reaction at the sites of numerous stings after disturbing an ant mound. He experienced no secondary complications, and his pustular lesions resolved with conservative treatment.
  71. ncbi [Calcified aortic stenosis in patients over 80 years of age. Results of surgical treatment. Observations in 67 consecutive cases]
    Y Logeais
    Clinique chirurgicale cardiovasculaire et thoracique, , Rennes
    Arch Mal Coeur Vaiss 83:1397-9. 1990
    ..1988 for calcific aortic stenosis in 67 consecutive patients over 80 years of age; the operative risk is assessed ant the results are compared with those of balloon valvuloplasty...
  72. pmc Over-expression of adenine nucleotide translocase 1 (ANT1) induces apoptosis and tumor regression in vivo
    Ji Young Jang
    Department of Pathology, Tumor Immunity Medical Research Center, Cancer Research Institute, Seoul National University College of Medicine, 28 Yeongeon dong, Jongno gu, Seoul 110 799, South Korea
    BMC Cancer 8:160. 2008
    ..Human ANT has four isoforms (ANT1, ANT2, ANT3, and ANT4), and the expression of the ANT isoforms is variable depending on the tissue and cell type, ..
  73. doi Adherence to imported fire ant subcutaneous immunotherapy
    Shayne C Stokes
    Division of Allergy and Immunology, Department of Medicine, Wilford Hall Medical Center, San Antonio, TX 78236, USA
    Ann Allergy Asthma Immunol 110:165-7. 2013
    Imported fire ant (IFA) subcutaneous immunotherapy (SCIT) is safe and effective. For optimal protection, SCIT is given monthly for 3 to 5 years. Successful outcomes require patient adherence.
  74. pmc Ant distribution in relation to ground water in north Florida pine flatwoods
    Walter R Tschinkel
    Department of Biological Science, Florida State University, Tallahassee, FL 32306 4370, USA
    J Insect Sci 12:114. 2012
    ..Here we describe how an important abiotic variable, depth to water table, relates to ant species distributions at local scales...
  75. doi Activated protein C attenuates intestinal mucosal injury after mesenteric ischemia/reperfusion
    Zafer Teke
    Department of General Surgery, Pamukkale University, School of Medicine, Denizli, Turkey
    J Surg Res 149:219-30. 2008
    Activated protein C (APC) is a serine protease with anticoagulant and ant-inflammatory activities. APC has been shown to attenuate deleterious effects of ischemia/reperfusion (I/R) injury in many organs...
  76. doi Monitoring Aethina tumida (Coleoptera: Nitidulidae) with baited bottom board traps: occurrence and seasonal abundance in honey bee colonies in Kenya
    Baldwyn Torto
    International Centre of Insect Physiology and Ecology ICIPE, P O Box 30772 00100, Nairobi, Kenya
    Environ Entomol 39:1731-6. 2010
    ..The ant Pheidole megacephala was identified as a key predator of larvae at this site, and more active during the dry than ..
  77. pmc Non-additive benefit or cost? Disentangling the indirect effects that occur when plants bearing extrafloral nectaries and honeydew-producing insects share exotic ant mutualists
    Amy M Savage
    Department of Biology, North Carolina State University, Raleigh, NC 27607, USA
    Ann Bot 111:1295-307. 2013
    ..nectar. In this study, a test was made for non-additive effects on HPI and EFN-bearing plants resulting from sharing exotic ant guards. Preferences of the dominant exotic ant species for nectar vs. honeydew resources were also examined.
  78. doi The rewards of restraint in the collective regulation of foraging by harvester ant colonies
    Deborah M Gordon
    Department of Biology, Stanford University, Stanford, California 94305 5020, USA
    Nature 498:91-3. 2013
    ..An ant colony operates without central control, regulating its activity through a network of local interactions...
  79. doi Linear antimicrobial peptides from Ectatomma quadridens ant venom
    Kirill A Pluzhnikov
    Shemyakin Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul Miklukho Maklaya, 16 10, 117997 Moscow, Russia
    Biochimie 107:211-5. 2014
    Venoms from three poneromorph ant species (Paraponera clavata, Ectatomma quadridens and Ectatomma tuberculatum) were investigated for the growth inhibition of Gram-positive and Gram-negative bacteria. It was shown that the venom of E...
  80. doi Mitochondrial gene expression in the liver and muscle of high and low feed efficiency Japanese quail layers subjected to different environmental temperatures
    D M Voltolini
    Departamento de Zootecnia, Universidade Estadual de Maringa, Maringa, PR, Brasil
    Genet Mol Res 13:4940-8. 2014
    We evaluated the adenine nucleotide translocator (ANT) and cytochrome oxidase subunit III (COX III) mRNA expressions in the muscle and liver of Japanese quails presenting high and low feed efficiency (FE), and subjected them to three ..
  81. pmc Wolbachia in the flesh: symbiont intensities in germ-line and somatic tissues challenge the conventional view of Wolbachia transmission routes
    Crystal L Frost
    Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom
    PLoS ONE 9:e95122. 2014
    ..focused on reproductive tissues of eusocial insects, and that non-reproductive tissues of queens and workers of the ant Acromyrmex echinatior, harbour substantial infections...
  82. doi Escovopsis trichodermoides sp. nov., isolated from a nest of the lower attine ant Mycocepurus goeldii
    Virginia E Masiulionis
    Centro de Estudos de Insetos Sociais, Instituto de Biociencias, Unesp Univ Estadual Paulista, Campus de Rio Claro, Rio Claro, SP, 13506 900, Brazil
    Antonie Van Leeuwenhoek 107:731-40. 2015
    ..The fifth species, Escovopsis aspergilloides was isolated from a nest of the higher attine ant Trachymyrmex ruthae from Trinidad...
  83. ncbi Linking traits of foraging animals to spatial patterns of plants: social and solitary ants generate opposing patterns of surviving seeds
    Tal Avgar
    The Movement Ecology Laboratory, Department of Evolution, Systematics and Ecology, Alexander Silberman Institute of Life Science, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel
    Ecol Lett 11:224-34. 2008
    ..We designed an extensive set of field experiments to test how seed predation by two harvester ant species interact with seed dispersal in shaping the spatial patterns of surviving seeds...
  84. doi Encapsulation of biogenic and synthetic polyamines by nanoparticles PEG and mPEG-anthracene
    S Sanyakamdhorn
    Department of Chemistry Physics, University of Quebec in Trois Rivieres, C P 500, Trois Rivieres, Quebec G9A 5H7, Canada
    J Photochem Photobiol B 130:30-9. 2014
    ..5×10(5)M(-1), KBE-333-PEG-8000=4.5×10(4)M(-1), KBE-3333-PEG-8000=2.2×10(5)M(-1), Kspm-mPEG-ant=6.5×10(5)M(-1), Kspmd-mPEG-ant=1.1×10(6)M(-1), KBE-333-mPEG-ant=2.2×10(5)M(-1) and KBE-3333-mPEG-ant=6...
  85. doi Invasion history of Solenopsis invicta (Hymenoptera: Formicidae) in Fujian, China based on mitochondrial DNA and its implications in development of a control strategy
    Xiang Zhang
    Fujian Provincial Key Laboratory of Insect Ecology, Department of Plant Protection, Fujian Agriculture and Forestry University Key Laboratory of Integrated Pest Management on Crops in Fujian Taiwan, Ministry of Agriculture, Fuzhou, China
    Insect Sci 21:493-8. 2014
    ..As there were populations of red imported fire ant, S...
  86. doi Source apportionment of sedimentary hydrocarbons in the Segara Anakan Nature Reserve, Indonesia
    Agung Dhamar Syakti
    Fisheries and Marine Sciences Department, Jenderal Soedirman University, Kampus Perikanan Unsoed Karangwangkal, Jl dr Suparno, Purwokerto 53123, Indonesia Electronic address
    Mar Pollut Bull 74:141-8. 2013
    ..g., Ant/∑178, Fl/∑202, BaAnt/∑228, and IPyr/∑276), showed that the sources of hydrocarbons in the sediments were ..
  87. doi Mandible strike: the lethal weapon of Odontomachus opaciventris against small prey
    Aldo De la Mora
    El Colegio de la Frontera Sur, Depto Entomología Tropical, Apdo Postal 36, Tapachula 30700, Chiapas, Mexico
    Behav Processes 78:64-75. 2008
    ..study both the hunting efficiency and the flexibility of their predatory behavior, solitary hunters of the trap-jaw ant Odontomachus opaciventris were offered small prey (termites, fruit flies and tenebrionid larvae), presenting ..
  88. doi Limitation of infarct size by erythropoietin is associated with translocation of Akt to the mitochondria after reperfusion
    Hironori Kobayashi
    Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
    Clin Exp Pharmacol Physiol 35:812-9. 2008
    ..increased phospho-Akt in the mitochondria and induced complex formation of Akt with adenine nucleotide translocase (ANT), a major subunit of mPTP, upon reperfusion. 3...
  89. doi The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells
    Annalisa Lena
    Dipartimento di Morfologia Umana e Biologia Applicata, University of Pisa, Pisa, Italy
    FEBS J 277:2853-67. 2010
    ..By contrast, the silencing of ANT1 isoform strongly reduced ADF cell viability by inducing a non-apoptotic cell death process resembling paraptosis...
  90. pmc Comparative genomics of chemosensory protein genes reveals rapid evolution and positive selection in ant-specific duplicates
    J Kulmuni
    Department of Biology and Biocenter Oulu, University of Oulu, Finland
    Heredity (Edinb) 110:538-47. 2013
    ..Here we annotated chemosensory protein (CSP) genes from seven ant genomes and studied their evolution...
  91. pmc Evidence that a transcription factor regulatory network coordinates oxidative stress response and secondary metabolism in aspergilli
    Sung Yong Hong
    Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan 48824, USA
    Microbiologyopen 2:144-60. 2013
    ..A novel conserved motif 5'-T/GNT/CAAG CCNNG/AA/GC/ANT/C-3' was identified in promoters of the aflatoxin biosynthetic and stress-response genes...
  92. pmc The importance of using multiple approaches for identifying emerging invasive species: the case of the Rasberry Crazy Ant in the United States
    Dietrich Gotzek
    Department of Entomology, National Museum of Natural History, Smithsonian Institution, Washington, District of Columbia, United States of America
    PLoS ONE 7:e45314. 2012
    In the past decade, Houston, Texas has been virtually overrun by an unidentified ant species, the sudden appearance and enormous population sizes and densities of which have received national media attention...
  93. pmc Ground dwelling ants as surrogates for establishing conservation priorities in the Australian wet tropics
    Sze Huei Yek
    School of Marine and Tropical Biology, James Cook University, Townsville 4811, Australia
    J Insect Sci 9:12. 2009
    ..We identified sites of high biodiversity value across an altitudinal gradient of ground dwelling ant communities using three measures of biodiversity...
  94. doi The importance of workers for queen hibernation survival in Camponotus ants
    Akiyoshi Shiroto
    Department of Biology, Faculty of Science, Yamagata University, 1 4 12 Kojirakawa machi, Yamagata shi 990 8560, Japan
    Zoolog Sci 28:327-31. 2011
    The higher proportion of polygynous ant species in northern areas indicates that cold climates influence queen number per colony...
  95. doi Effect of an invasive ant and its chemical control on a threatened endemic Seychelles millipede
    James M Lawrence
    Department of Conservation Ecology and Entomology, Faculty of AgriSciences, Stellenbosch University, Private Bag X01, Matieland, 7602, South Africa
    Ecotoxicology 20:731-8. 2011
    ..Here, we study the impact of the invasive African big-headed ant, Pheidole megacephala, on a small Seychelles island, Cousine, and assess the impact of this ant, and its chemical ..
  96. doi Biodiversity conservation, ecosystem functioning, and economic incentives under cocoa agroforestry intensification
    D H B Bisseleua
    Georg August University Goettingen, Department of Crop Science, Entomological Section, Grisebachstr 6, 37077 Goettingen, Germany
    Conserv Biol 23:1176-84. 2009
    ..Here we describe the relationships between ant ecology (species richness, community composition, and abundance) and vegetation structure, ecosystem functions, and ..
  97. pmc Symbiont interactions in a tripartite mutualism: exploring the presence and impact of antagonism between two fungus-growing ant mutualists
    Michael Poulsen
    Department of Bacteriology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 5:e8748. 2010
    ..Within both ant-fungus and ant-bacterium mutualisms, mixing of genetically distinct strains can lead to antagonistic interactions (..
  98. pmc More individuals but fewer species: testing the 'more individuals hypothesis' in a diverse tropical fauna
    Terrence P McGlynn
    Department of Biology, California State University Dominguez Hills, Carson, CA, USA
    Biol Lett 6:490-3. 2010
    ..While large-scale correlations between ant diversity and net primary productivity or temperature are reconcilable with the MIH, key elements of the hypothesis ..
  99. doi Simulated visual homing in desert ant natural environments: efficiency of skyline cues
    Kai Basten
    Institute of Neurobiology, University of Tubingen, Auf der Morgenstelle 28, 72076, Tubingen, Germany
    Biol Cybern 102:413-25. 2010
    ..e. the skyline, provides sufficient information for visual navigation. We constructed a virtual model of the ant's environment...
  100. pmc Rapid anti-pathogen response in ant societies relies on high genetic diversity
    Line V Ugelvig
    Evolution, Behaviour and Genetics, Biology I, University of Regensburg, Universitatsstrasse 31, 93040 Regensburg, Germany
    Proc Biol Sci 277:2821-8. 2010
    ..the effects of high versus low genetic diversity on both the individual and collective disease defences in the ant Cardiocondyla obscurior...
  101. pmc Synergy between social and private information increases foraging efficiency in ants
    Tomer J Czaczkes
    Laboratory of Apiculture and Social Insects, School of Life Sciences, University of Sussex, Falmer BN19QG, UK
    Biol Lett 7:521-4. 2011
    ..and low-quality information, such as trail pheromones, when route memory is available? Here we show that, in the ant Lasius niger, trail pheromones and route memory act synergistically during foraging; increasing walking speed and ..

Research Grants65

  1. Argentine ants: A system a study genes involved in human behavioral disease
    CHRISTOPHER DAVID SMITH; Fiscal Year: 2010
    ..propose to perturb the expression level of genes from the WBSCR in the social insect, Linepithema humile (Argentine ant)...
  2. Stochastic integrator models of collective decision-making
    Deborah M Gordon; Fiscal Year: 2013
    ..Our long-term goal is to use the red harvester ant, Pogonomyrmex barbatus, as a model for investigating the collective regulation of behavior that leads to the ..
  3. Regulation of variable lifespan in castes of ants
    Hua Yan; Fiscal Year: 2013
    ..In response to environmental cues, genetically identical individuals in the ant species Harpegnathos saltator can switch to more than 5 times longer lifespan, with changes in reproduction and ..
  4. Developing Male Contraceptives by Targeting ANT4
    Naohiro Terada; Fiscal Year: 2013
    ..Among the four isoforms (Ant1-4) found in mammals, Ant4 is exclusively expressed in male germ cells...
  5. Senescence, neurodegeneration, and sensory/motor decline in a social invertebrate
    Ysabel Milton Giraldo; Fiscal Year: 2013
    ..The development of a social invertebrate model of aging, the ant Pheidole dentata, presents multiple advantages in the analysis of aging. 1...
  6. MECHANISM OF ACTION OF FIRE ANT VENOM
    NANCY LIND; Fiscal Year: 1980
    ..to determine the extent to which the piperidine components of the venom are responsible for the effects of fire ant stings, to investigate whether the antimicrobial activity of the venom is also due to membrane disruption, to ..
  7. ANT Defects in Neurodegenerative Diseases
    Douglas Wallace; Fiscal Year: 2005
    ..Humans have three ANT isoform genes: the heart-muscle ANT1, the inducible ANT2, and the constitutive ANT3...
  8. Studying the molecular mechanisms of social life using a novel ant model system
    DANIEL KRONAUER; Fiscal Year: 2012
    ..Here I propose to develop and use a novel genetic model system, the ant Cerapachys biroi, to study the following main questions. 1...
  9. CHEMICAL CONTROL OF SOCIAL BEHAVIOR
    Michael Greene; Fiscal Year: 2003
    ..using a comparative model system: the chemical control of social behavior in a social insect, the harvester ant (Pogonomyrmex barbatus)...
  10. Nanoelectrode arrays for study of the molecular mechanisms, triggers, and inhibit
    Peter J Burke; Fiscal Year: 2012
    ..in the Akt signal transduction pathway, induction of hexokinase II, alteration an adenine nucleotide translocator (ANT) isoform expression, down regulation of the SOC2 cytochrome c oxidase (complex IV, COX) assembly factor, mutation ..
  11. SECRETION AND BIOSYNTHESIS OF INSULIN
    Michael L McDaniel; Fiscal Year: 2012
    ..signaling by A) examining if RNA interference of nitric oxide synthase (NOS) isoforms or MTP components, VDAC &ANT, alter the physiological responses of rodent &human islets to nutrients or GSK-3 inhibition, B) evaluating the ..
  12. A semi field trial test on efficacy of transgenic antimalarial biocontrol fungi
    Raymond J St Leger; Fiscal Year: 2013
    ..to express arthropod toxins in comparison with a strain with wild type virulence to insects but expressing ant-malarial proteins that reduce the parasite burden in mosquitoes by 98%...
  13. Role of CD98 Glycoprotein in Intestinal Inflammation
    Hamed Laroui; Fiscal Year: 2013
    ..Finally, my third aim will investigate the site-directed delivery of ant-CD98 siRNA using non-viral vectors encapsulated in nanoparticles (NPs) as carriers effectively inhibits induced ..
  14. MOLECULAR REGULATION OF MUSCLE GLUCOSE METABOLISM IN MAN
    Lawrence J Mandarino; Fiscal Year: 2013
    ..these techniques we also propose 3) to determine how acetylation of mitochondrial adenine nucleotide translocase (ANT1) at lysines 10, 23, and 92 regulates ANT1 structure and function...
  15. A Phase 0 Trial of Hydroxychloroquine in Patients with Stage III and IV Resectabl
    Janice Mehnert; Fiscal Year: 2010
    ..Potential proapoptotic and/or ant proliferative effects of HCQ will also be explored through the use of pre- and post-treatment activated caspase-3, ..
  16. ADP: A Master Regulator for Bioenergetics and Ca2+/ROS Signaling in Heart
    Shey Shing Sheu; Fiscal Year: 2012
    ..One indicates that adenine nucleotide translocase (ANT) is not required for mPTP, whereas the other depicts mPTP as a multi-protein complex, the ANT and the mitochondrial ..
  17. RECEPTOR-TARGETED COPPER RADIOPHARMACEUTICALS FOR CANCER IMAGING AND THERAPY
    Carolyn J Anderson; Fiscal Year: 2012
    ..We propose to utilize the most promising somatostatin antagonist, sst2-ANT, conjugated to CB-TE2A, which complexes copper more stably in vivo than any other chelator investigated thus far...
  18. Role of mitochondria in cardiac protection
    Peipei Ping; Fiscal Year: 2010
    ..Furthermore, our preliminary data demonstrate for the first time that multiple isoforms of VDAC (VDAC1-3) and ANT (ANT1-2) are expressed in the adult mouse heart as detected by both immunoblotting (using antibodies we developed since ..
  19. CMV Entry-Specific Neutralizing Antibody in Primary Infection in Transplantation
    Margaret L Green; Fiscal Year: 2013
    ..Finally, in the third aim, I will characterize the influence of ant-UL131-128 neutralizing antibodies in preventing late CMV disease following primary infection in liver ..
  20. Cardiolipin and the mitochondrial ADP/ATP carrier interactome
    STEVEN MICHAEL CLAYPOOL; Fiscal Year: 2013
    ..b>ANT1 deficiencies and mutations have been linked to numerous diseases including hypertrophic cardiomyopathy...
  21. Mechanisms of In Vivo Ethanol-Induced Mitochondrial Depolarization
    Zhi Zhong; Fiscal Year: 2010
    ..we will focus on Ca2+ cycling via the Ca2+uniporter, proton leak through the adenine nucleotide transporer (ANT), and proton leak through F0 proton channel of F1F0 ATP synthase...
  22. Development and Translational Assesment of a Tongue-Based Assistive Neuro-Technol
    Maysam Ghovanloo; Fiscal Year: 2010
    ..06-NS-104 Abstract/summary: Development and Translational Assessment of a Tongue-Based Assistive Neuro-Technology (ANT) for Individuals with Severe Neurological Disorders More than two million Americans suffer from paralysis as a ..
  23. Wireless ECoG Recording for Epilepsy Monitoring
    Stuart F Cogan; Fiscal Year: 2013
    ..to 29 days, which allows the recording of habitual seizure activity while the patient is on their full regimen of ant-seizure medication...
  24. Re-setting the Endothelial Ceramide Rheostat
    Richard N Kolesnick; Fiscal Year: 2013
    ..Practically, combining ant- VEGF strategies under conditions that re-set ASMase activation can be taken to the clinic almost immediately...
  25. NEUROTOXIC MECHANISM OF METHYLMERCURY POISONING
    William D Atchison; Fiscal Year: 2012
    ..chronic adult-onset (lifetime) exposure to MeHg accelerates cerebellar synaptic dysfunction associated with aging, ant its'sensitivity to protection by Ca2+ channel blocker treatment...
  26. Aging-related mitochondrial degeneration and degenerative diseases
    Xin Jie Chen; Fiscal Year: 2013
    ..External Ophthalmoplegia (adPEO), caused by gain-of-function mutations in the adenine nucleotide translocase (Ant). Ant is normally involved in ADP/ATP exchange across the mitochondrial inner membrane...
  27. HNE damage of adenine nucleotide translocase in ethanol-mediated neuron apoptosis
    George I Henderson; Fiscal Year: 2010
    ..transition pore complex and possibly apoptosis activation, is perturbation of adenine nucleotide translocase (ANT) function by 4- hydroxynonenal (HNE) adduct formation...
  28. Role of nebula/DSCR1 in mitochondria
    Karen T Chang; Fiscal Year: 2011
    ..addition, we found that nebula is located ih the mitochondria, interacts with the adenine nucleotide ti-ansjocator (ANT), and is important for the maintenance of nriitochondrial functipn and integrity...
  29. SIRT1, Nitro-Lipids and Cardioprotection
    Paul S Brookes; Fiscal Year: 2013
    ..nitro-lipids is generated in IPC, and covalently adducts mitochondrial adenine nucleotide translocase 1 (ANT1)...
  30. Living Delivery Systems to Promote Vascular Development in 3D Scaffolds
    James Blanchette; Fiscal Year: 2013
    ..Cell viability, expression of pro- and ant-apoptotic proteins, secretion of angiogenic factors and tracking osteogenic differentiation of the ASCs are some of ..
  31. Drug Abuse, Sustance P and HIV
    Wenzhe Ho; Fiscal Year: 2013
    ..We will focus on the impact of opioids and/or SP on type 1 IFN- and APOBEC3G/3F (newly identified ant-HIV factors)-mediated innate immunity against HIV-1, as these cellular factors are the key elements of anti-HIV ..
  32. Molecular Biology and Genetics of Human Tumor Viruses
    Paul F Lambert; Fiscal Year: 2013
    ..human tumor viruses and to translate this understanding into the identification of targets for specific anti-viral, ant-tumor therapies...
  33. Chemoprevention of inflammation-driven lung cancer
    Fekadu Kassie; Fiscal Year: 2013
    ..mouse model for inflammation-driven lung cancer and showed in in vitro studies with lung cancer cell lines that the ant proliferative and apoptotic effects of I3C plus SB were paralleled b decreased activation of the pro-inflammatory ..
  34. Dual Action Inhibitors of Gyrase Beta and Histidine Kinases as Broad-Spectrum Ant
    Peter B Madrid; Fiscal Year: 2010
    ..apos; E; T-- <.-n[unreadable] _0:N O'[unreadable] >.Q -a. =-r (II N-0 Q--:nZ U)' ..
  35. Adoptive T Cell Therapy Following CD25 Lymphodepletion
    Cassian Yee; Fiscal Year: 2010
    ..by a CD25hi CD4 phenotype) are found at increased levels in patients with cancer, and may thwart an effective ant-tumor T cell response by suppressing T cell activation and effector function...
  36. Mortality and Macroeconomic Conditions: Differential Vulnerability and Mechanism
    JOSE A TAPIA GRANADOS; Fiscal Year: 2010
    ..A better understanding of the relative contributions of different causes of death ant the vulnerability of different demographic groups will shed light on the causes of these fluctuations, and will ..
  37. Evaluation of marketed drugs for rapid development as anti-cryptosporidal agents
    Guan Zhu; Fiscal Year: 2013
    ..of Cryptosporidium in vitro, we plan to extend our discovery by screening all existing drugs for their potential ant-cryptosporidia activities in vitro and in vivo...
  38. Optimizing Peripheral Nerve Regeneration using Computational Intelligence based T
    Xiaojun Yu; Fiscal Year: 2011
    ..Two swarm intelligence based methods, Ant Colony Optimization (ACO) and Particle Swarm Optimization (PSO), will be applied in this project to train the ANN ..
  39. Anchor: A PDB-Wide And Web-Based Discovery Resource Of Small Molecular Weight Pro
    ALEXANDER SIEGFRIED contact DOEMLING; Fiscal Year: 2010
    ..applicant): R21: ANCHOR: A PDB-Wide And Web-based Discovery Resource of Small Molecular Weight Protein Interaction (Ant)agonists...
  40. PBEF Neutralizing Humanized Monoclonal Antibodies As Novel Therapeutic Approaches
    Joe G N Garcia; Fiscal Year: 2012
    ..We therefore propose to generate humanized ant-PBEF monoclonal antibodies (P- BEFizumab) that can be used as both prophylactic and therapeutic agents in patients ..
  41. Molecular Identity of the Cardiac Mitochondrial Pore
    CHRISTOPHER PHILIP BAINES; Fiscal Year: 2013
    ..to consist of the voltage-dependent anion channel (VDAC) in the outer membrane, the adenine nucleotide translocase (ANT) in the inner membrane, plus a regulatory protein cyclophilin-D (CypD) in the matrix...
  42. Astrocyte-mediated neuroprotection after CNS injury
    Robert McKeon; Fiscal Year: 2005
    ..We have discovered that expression of the Adenine Nucleotide Translocator-1 (Ant1) by reactive astrocytes increases after cortical injury and that this increase is mediated by the injury-induced ..
  43. Cannabimimetic Ligands and Endocannabinoid Active Sites
    MAKRIYANNIS ALEXANDROS; Fiscal Year: 2011
    ..Monacyl Glycerol Ligase (MGL), the oxidative enzyme Cyclooxygenase-2 (COX-2), and the Anandamide Transport system (ANT)...
  44. MOLECULAR BASIS OF CANNABINOID ACTIVITY
    Alexandros Makriyannis; Fiscal Year: 2013
    ..This information was used to design, synthesize and develop later generation CBR (ant) agonists with distinct pharmacological profiles either as molecular probes or leads for medications development...
  45. Defining the Mechanisms by Which Plateletes Regulate Angiogenesis
    Elisabeth M Battinelli; Fiscal Year: 2013
    ..To investigate the role of the platelet in storage, delivery, and function of ant-angiogenic therapy...
  46. A Fluorescence Displacement Assay for the Biotin Biosynthetic Enzyme BioA
    Courtney C Aldrich; Fiscal Year: 2013
    ..Biotin biosynthesis has recently been identified as an attractive target for the development of new ant tubercular agents...
  47. Mechanisms of Attention Deficits in Children with Heavy Prenatal Alcohol Exposure
    SARAH N MATTSON WELLER; Fiscal Year: 2012
    ..More specifically, the proposed study will use the Attention Network Test (ANT), which was designed to assess three attention networks (orient, alert, executive control) that underlie visual ..
  48. An Animal model to develop therapeutic strategies for FSHD
    Rossella G Tupler; Fiscal Year: 2011
    ..Expression analysis to all known genes mapping at 4q35, revealed that ANT1, FRG1, and FRG2 genes were over-expressed in FSHD affected muscle...
  49. "Protein protein interaction directed libraries"
    Billy W Day; Fiscal Year: 2012
    ..protein interaction directed compound libraries" will produce 1,760 compounds based on 56 scaffolds aiming to (ant-) agonize protein protein interaction (PPI)...
  50. Calcium Regulation in the Progression of Muscular Dystrophy
    Noah Weisleder; Fiscal Year: 2013
    ..The focus of this project is to test the hypothesis that aben-ant Ca spark activity acts as a trigger for SOCE and thus induces a dystrophic cascade in mammalian skeletal muscle ..
  51. ANCHOR: A PDB-Wide Real Time Discovery Resource of Novel PPI (Ant)-agonists
    ALEXANDER SIEGFRIED DOEMLING; Fiscal Year: 2013
    ..worldwide research groups with in vitro and/or in vivo assays with the goal of developing small molecular weight (ant)agonists...
  52. Altered Nuclear Transfer
    Shoukhrat M Mitalipov; Fiscal Year: 2013
    ..We propose the following specific aims: Aim 1. Establish a mouse model of ANT with improved ESC derivation...
  53. Genome Sequencing in Extended Bipolar Pedigrees
    Nelson B Freimer; Fiscal Year: 2013
    ..are drawn from the related population isolates of the Central Valley of Costa Rica (CVCR) and Antioquia, Colombia (ANT)...
  54. PKC EPSILON AND SRC PTK SIGNALING IN PRECONDITIONING
    Peipei Ping; Fiscal Year: 2009
    ..Interestingly, we identified the cardiac isoform of the adenine nucleotide translocase (ANT1) as a member of the PKCepsilon sub-proteome...
  55. BIOLOGICAL TESTING FACILITY - CDB-2914 OR RELATED COMPOUND, MOUSE/RAT/RABBIT TO
    KATHRYN BAUGHMAN; Fiscal Year: 2011
    ..to permit rapid evaluation of new compositions of matter, drug formulations, delivery systems, and devices for ant-fertility and endocrine activity NICHD has supported investigators who are aggressively researching different ..
  56. OLIGONUCLEOTIDE INHIBITION OF CELL PROLIFERATION
    Eric Wickstrom; Fiscal Year: 2000
    ..The central hypothesis of this application is that second and third generation derivatives of ant-c-myc DNAs will display greater systemic potency than phosphorothioates in animal models of c-myc- dependent ..
  57. Applied Research on Antimicrobial Resistance (AR)
    Ruth Lynfield; Fiscal Year: 2006
    ..We plan to construct a utilization profile comprised of individual elements such as length-of-stay ant procedures. We will also collect indirect costs, such as days lost from work, through case interviews...
  58. BIOLOGICAL TESTING FACILITY - CDB-4754
    KATHRYN BAUGHMAN; Fiscal Year: 2011
    ..to permit rapid evaluation of new compositions of matter, drug formulations, delivery systems, and devices for ant-fertility and endocrine activity NICHD has supported investigators who are aggressively researching different ..
  59. Identification of Novel Genes Expressed in Bowel Cancer Using Change Mediated Ant
    Jeffrey Hillman; Fiscal Year: 2007
    ..Such proteins are likely to be useful in monitoring treatment, diagnosing this disease, and in preventing it. [unreadable] [unreadable] [unreadable]..
  60. Demand for Older Workers
    JOHN ABOWD; Fiscal Year: 2004
    ..There are two sides to these experiences: (1) the decisions of the individuals ant heir households and (2) the decisions of the employers...
  61. Pathogenesis and Therapy of Sideroblastic Anemia
    Jeffrey Friedman; Fiscal Year: 2007
    ..SOD2, is a critical intra-mitochondrial catalytic ant/oxidant, and deficiency of this enzyme leads to late embryonic or neonatal lethality in mice, with pathologic ..
  62. CONTROL MECHANISMS IN INTERMEDIARY METABOLISM
    EARL SHRAGO; Fiscal Year: 1990
    ..on one of the more important proteins in cellular bioenergetics, namely the adenine nucleotide translocase (ANT) located in the inner mitochondrial membrane...
  63. OBESE FEMALE RESTRAINED EATERS : TWO TREATMENT OPTIONS
    Judith Stern; Fiscal Year: 2002
    ..Restrained eaters are individuals who are chronically concerned about their weight ant attempt to control or reduce it by limiting their energy intake...
  64. The Mitochondrial Permeabilty Transition in Apoptosis
    Brian Herman; Fiscal Year: 2005
    ..of the outer membrane voltage-dependent anion channel (VDAC), the inner membrane adenine nucleotide translocase (ANT) and matrix cyclophilin D (CypD)...
  65. CD45 AND GENERATION OF ISLET ALLOGRAFT TOLERANCE
    David Rothstein; Fiscal Year: 2005
    ..Important lead data now indicate that the ant.i-CD45-mediated shift in CD45 isoforms is associated with an upregulation of CTLA-4, a potent inhibitory molecule ..