Genomes and Genes
Gene Symbol: SLC22A23
Description: solute carrier family 22 member 23
Alias: C6orf85, solute carrier family 22 member 23, ion transporter protein
- Aberg K, Adkins D, Liu Y, McClay J, BukszÃ¡r J, Jia P, et al. Genome-wide association study of antipsychotic-induced QTc interval prolongation. Pharmacogenomics J. 2012;12:165-72 pubmed publisher..10 (P-value=1.54 Ã— 10(-7), Q-value=0.07), located in SLC22A23, mediated the effects of quetiapine on prolongation...
- Anderson C, Massey D, Barrett J, Prescott N, Tremelling M, Fisher S, et al. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology. 2009;136:523-9.e3 pubmed publisher..ECM1 variation was not associated with CD. Collectively, these data help define the genetic relationship between CD and UC and characterize common, as well as disease-specific mechanisms of pathogenesis. ..
- Weersma R, Stokkers P, Cleynen I, Wolfkamp S, Henckaerts L, Schreiber S, et al. Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. Am J Gastroenterol. 2009;104:630-8 pubmed publisher..We show that a genetic risk profile can be constructed that is clinically useful and that can aid in making treatment decisions. ..
- Serrano León A, Amir Shaghaghi M, Yurkova N, Bernstein C, El Gabalawy H, Eck P. Single-nucleotide polymorphisms in SLC22A23 are associated with ulcerative colitis in a Canadian white cohort. Am J Clin Nutr. 2014;100:289-94 pubmed publisherb>SLC22A23 is an orphan gene in the SLC22 family of organic membrane transporters, and its single-nucleotide polymorphism rs17309827-T was recently nominally associated with intestinal inflammation in a genome-wide association study...