Gene Symbol: SH3PXD2A
Description: SH3 and PX domains 2A
Alias: FISH, SH3MD1, TKS5, SH3 and PX domain-containing protein 2A, SH3 multiple domains 1, adapter protein TKS5, adaptor protein TKS5, five SH3 domain-containing protein, tyrosine kinase substrate with five SH3 domains
Species: human
Products:     SH3PXD2A

Top Publications

  1. Lock P, Abram C, Gibson T, Courtneidge S. A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate. EMBO J. 1998;17:4346-57 pubmed
    ..Several potential Src substrates were identified including Fish, which has five SH3 domains and a recently discovered phox homology (PX) domain...
  2. Abram C, Seals D, Pass I, Salinsky D, Maurer L, Roth T, et al. The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells. J Biol Chem. 2003;278:16844-51 pubmed
    b>Fish is a scaffolding protein and Src substrate. It contains an amino-terminal Phox homology (PX) domain and five Src homology 3 (SH3) domains, as well as multiple motifs for binding both SH2 and SH3 domain-containing proteins...
  3. Seals D, Azucena E, Pass I, Tesfay L, Gordon R, Woodrow M, et al. The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells. Cancer Cell. 2005;7:155-65 pubmed
    b>Tks5/Fish is a scaffolding protein with five SH3 domains and one PX domain. In Src-transformed cells, Tks5/Fish localizes to podosomes, discrete protrusions of the ventral membrane...
  4. Gianni D, Diaz B, Taulet N, Fowler B, Courtneidge S, Bokoch G. Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity. Sci Signal. 2009;2:ra54 pubmed publisher
    ..We show that the c-Src substrate proteins Tks4 (tyrosine kinase substrate with four SH3 domains) and Tks5 are functional members of a p47(phox)-related organizer superfamily...
  5. Stylli S, I S, Kaye A, Lock P. Prognostic significance of Tks5 expression in gliomas. J Clin Neurosci. 2012;19:436-42 pubmed publisher
    ..b>Tyrosine kinase substrate with five SH3 domains (Tks5, also known as SH3PXD2A) and cortactin are required for the formation of invadopodia, ..
  6. Xu H, Jiang W, Feng L, Liu Y, Wu P, Jiang J, et al. Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-κB, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;52:111-38 pubmed publisher
    ..05) in the head kidney and spleen under injection fish of A...
  7. Reperant L, Brown I, Haenen O, de Jong M, Osterhaus A, Papa A, et al. Companion Animals as a Source of Viruses for Human Beings and Food Production Animals. J Comp Pathol. 2016;155:S41-53 pubmed publisher
    ..a wide variety of species, including dogs, cats, horses, ferrets, guinea pigs, reptiles, birds and ornamental fish, as well as food production animal species, such as domestic pigs, kept as companion animals...
  8. Xu H, Jiang W, Feng L, Liu Y, Wu P, Jiang J, et al. Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare. Fish Shellfish Immunol. 2016;58:177-192 pubmed publisher
    ..columnare, suggesting that vitamin C deficiency induced oxidative injury in fish gill; (2) up-regulated caspase-3, -7, -8, -9, Fas ligand, B-cell lymphoma protein 2 associated X protein, apoptotic ..
  9. Li S, Feng L, Jiang W, Liu Y, Jiang J, Wu P, et al. Deficiency of dietary niacin impaired gill immunity and antioxidant capacity, and changes its tight junction proteins via regulating NF-?B, TOR, Nrf2 and MLCK signaling pathways in young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;55:212-22 pubmed publisher
    ..reductase, glutathione peroxidase and glutathione-S-transferase activities and reduced glutathione content in fish gills (P < 0.05)...

More Information

Publications148 found, 100 shown here

  1. Salas Huetos A, Bullo M, Salas Salvado J. Dietary patterns, foods and nutrients in male fertility parameters and fecundability: a systematic review of observational studies. Hum Reprod Update. 2017;23:371-389 pubmed publisher
    ..b>Fish, shellfish and seafood, poultry, cereals, vegetables and fruits, low-fat dairy and skimmed milk were positively ..
  2. Liu S, Feng L, Jiang W, Liu Y, Jiang J, Wu P, et al. Impact of exogenous lipase supplementation on growth, intestinal function, mucosal immune and physical barrier, and related signaling molecules mRNA expression of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;55:88-105 pubmed publisher
    ..high-lipid diet could improve growth, intestinal growth and function, immune response and antioxidant capability of fish. Meanwhile, in high-fat and low-protein diets, optimal exogenous lipase supplementation improved growth, intestinal ..
  3. Pan F, Feng L, Jiang W, Jiang J, Wu P, Kuang S, et al. Methionine hydroxy analogue enhanced fish immunity via modulation of NF-?B, TOR, MLCK, MAPKs and Nrf2 signaling in young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;56:208-228 pubmed publisher
    ..5 g/kg diet) and one dl-methionine (DLM) group (6.4 g/kg diet) for 8 weeks. At the end of the feeding trial, fish were challenged with Aeromonas hydrophila for 14 days...
  4. Chen L, Feng L, Jiang W, Jiang J, Wu P, Zhao J, et al. Dietary riboflavin deficiency decreases immunity and antioxidant capacity, and changes tight junction proteins and related signaling molecules mRNA expression in the gills of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;45:307-20 pubmed publisher
    ..b>Fish were fed six diets containing graded levels of riboflavin (0.63-10.04 mg/kg diet) for 8 weeks...
  5. Guo Y, Jiang W, Wu P, Liu Y, Zhou X, Kuang S, et al. The decreased growth performance and impaired immune function and structural integrity by dietary iron deficiency or excess are associated with TOR, NF-?B, p38MAPK, Nrf2 and MLCK signaling in head kidney, spleen and skin of grass carp (Ctenopharyngod. Fish Shellfish Immunol. 2017;65:145-168 pubmed publisher
    ..05), indicating that iron deficiency impaired immune function in head kidney and spleen of fish. Secondly, iron deficiency down-regulated the mRNA levels of B-cell lymphoma-2 (Bcl-2), myeloid cell leukemia 1 (..
  6. Gil Ã, Martínez de Victoria E, Olza J. Indicators for the evaluation of diet quality. Nutr Hosp. 2015;31 Suppl 3:128-44 pubmed publisher
    ..Other foods contained in some DQIs e.g. MDS are olive oil and fish. Nowadays, there is interest in defining more than DQIs, healthy life indices (HLIs), which give information on ..
  7. Li L, Feng L, Jiang W, Jiang J, Wu P, Zhao J, et al. Dietary pantothenic acid depressed the gill immune and physical barrier function via NF-κB, TOR, Nrf2, p38MAPK and MLCK signaling pathways in grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;47:500-10 pubmed publisher
    ..decreased immune and physical barrier function, and regulated relative mRNA levels of signaling molecules in fish gill...
  8. Shi L, Feng L, Jiang W, Liu Y, Jiang J, Wu P, et al. Folic acid deficiency impairs the gill health status associated with the NF-κB, MLCK and Nrf2 signaling pathways in the gills of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;47:289-301 pubmed publisher
    The aim of this study was to investigate the effect of dietary folic acid on fish growth, the immune and barrier functions of fish gills, and the potential mechanisms of these effects...
  9. Jiang W, Feng L, Qu B, Wu P, Kuang S, Jiang J, et al. Changes in integrity of the gill during histidine deficiency or excess due to depression of cellular anti-oxidative ability, induction of apoptosis, inflammation and impair of cell-cell tight junctions related to Nrf2, TOR and NF-?B signaling in fish. Fish Shellfish Immunol. 2016;56:111-122 pubmed publisher
    ..of dietary histidine on structural integrity and the related signaling factor gene expression in the gills of fish. Young grass carp (Ctenopharyngodon idella) were fed with six diets containing gradual levels of histidine for 8 ..
  10. Tian J, Wu F, Yang C, Jiang M, Liu W, Wen H. Dietary lipid levels impact lipoprotein lipase, hormone-sensitive lipase, and fatty acid synthetase gene expression in three tissues of adult GIFT strain of Nile tilapia, Oreochromis niloticus. Fish Physiol Biochem. 2015;41:1-18 pubmed publisher
    ..00 ± 9.54 g) into six groups consisting of four replicates (20 fish per replicate). Fish in each group were hand-fed a semi-purified diets containing different lipid levels [3...
  11. Feng L, Li W, Liu Y, Jiang W, Kuang S, Wu P, et al. Protective role of phenylalanine on the ROS-induced oxidative damage, apoptosis and tight junction damage via Nrf2, TOR and NF-?B signalling molecules in the gill of fish. Fish Shellfish Immunol. 2017;60:185-196 pubmed publisher
    ..b>Fish were fed six different experimental diets containing graded levels of Phe (3.4-16...
  12. Kabel A, Abd Elmaaboud M, Albarraq A. Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. Prostaglandins Leukot Essent Fatty Acids. 2015;96:1-9 pubmed publisher
    ..control group, high fat emulsion/sucrose (HFE/S) diet, HFE/S+carboxymethyl cellulose, HFE/S +Atorvastatin, HFE/S+Fish oil and HFE/S+Atorvastatin+Fish oil...
  13. Jiang W, Xu J, Zhou X, Wu P, Liu Y, Jiang J, et al. Dietary protein levels regulated antibacterial activity, inflammatory response and structural integrity in the head kidney, spleen and skin of grass carp (Ctenopharyngodon idella) after challenged with Aeromonas hydrophila. Fish Shellfish Immunol. 2017;68:154-172 pubmed publisher
    ..7, 217.2, 257.5, 292.2 and 322.8 g digestible protein kg-1 diet) for 8 weeks. After the growth trial, fish were challenged with Aeromonas hydrophila for 14 days...
  14. Wu P, Tian L, Zhou X, Jiang W, Liu Y, Jiang J, et al. Sodium butyrate enhanced physical barrier function referring to Nrf2, JNK and MLCK signaling pathways in the intestine of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2018;73:121-132 pubmed publisher
    ..The fish were fed one powdery sodium butyrate (PSB) diet (1000...
  15. Zeng Y, Feng L, Jiang W, Liu Y, Wu P, Jiang J, et al. Dietary alpha-linolenic acid/linoleic acid ratios modulate immune response, physical barrier and related signaling molecules mRNA expression in the gills of juvenile grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2017;62:1-12 pubmed publisher
    ..b>Fish were fed diets with different ALA/LNA ratios (0.01, 0.34, 0.68, 1.03, 1.41, 1.76 and 2.15) for 60 days...
  16. Feng L, Luo J, Jiang W, Liu Y, Wu P, Jiang J, et al. Changes in barrier health status of the gill for grass carp (Ctenopharyngodon idella) during valine deficiency: Regulation of tight junction protein transcript, antioxidant status and apoptosis-related gene expression. Fish Shellfish Immunol. 2015;45:239-49 pubmed publisher
    ..b>Fish were fed six different experimental diets containing graded levels of valine (4.3, 8.0, 10.6, 13.1, 16.7, 19...
  17. Qin N, Bayat A, Trevisi E, Minuti A, Kairenius P, Viitala S, et al. Dietary supplement of conjugated linoleic acids or polyunsaturated fatty acids suppressed the mobilization of body fat reserves in dairy cows at early lactation through different pathways. J Dairy Sci. 2018;101:7954-7970 pubmed publisher
    ..linoleic acid (CLA)-supplemented diet, or a high-starch diet supplemented with a mixture of sunflower and fish oil (2:1; as HSO diet) from 1 to 112 d in milk...
  18. Jiang W, Wen H, Liu Y, Jiang J, Kuang S, Wu P, et al. The tight junction protein transcript abundance changes and oxidative damage by tryptophan deficiency or excess are related to the modulation of the signalling molecules, NF-κB p65, TOR, caspase-(3,8,9) and Nrf2 mRNA levels, in the gill of young gras. Fish Shellfish Immunol. 2015;46:168-80 pubmed publisher
    ..b>Fish were fed with six different experimental diets containing graded levels of Trp at 0.7 (control), 1.7, 3.1, 4.0, 5...
  19. Pan Y, Luo Z, Zhuo M, Wei C, Chen G, Song Y. Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio. Aquat Toxicol. 2018;199:12-20 pubmed publisher
    ..and explore the underlying molecular mechanism of cadmium (Cd)-induced disorder of hepatic lipid metabolism in fish. To this end, adult zebrafish were exposed to three waterborne CdCl2 concentrations (0(control), 5 and ..
  20. Bohnert H, Maurer M, Calder P, Pratschke J, Thul P, Müller V. Efficacy of a long-term home parenteral nutrition regimen containing fish oil-derived n-3 polyunsaturated fatty acids: a single-centre, randomized, double blind study. Nutr J. 2018;17:113 pubmed publisher
    Data on the use of lipid emulsions containing fish-oil (FO) derived n-3 polyunsaturated fatty acids (n-3 PUFAs) in addition to medium- and long-chain triglycerides (MCT/LCT) for long-term home parenteral nutrition (HPN) are limited...
  21. Yong C, Yeap S, Omar A, Tan W. Advances in the study of nodavirus. Peerj. 2017;5:e3841 pubmed publisher
    ..In addition, immune responses of fish and prawn are also discussed...
  22. Wu P, Pan F, Feng L, Jiang W, Jiang J, Kuang S, et al. Methionine hydroxy analogue supplementation modulates gill immunological and barrier health status of grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2018;74:637-648 pubmed publisher
    ..4, 8.5 and 10.5?g/kg diet) and one DL-methionine (DLM) group (6.4?g/kg diet) for 8 weeks. After feeding trial, 15 fish from each treatment were challenged with Flavobacterium columnare...
  23. Kumar N, Krishnani K, Gupta S, Singh N. Effects of silver nanoparticles on stress biomarkers of Channa striatus: immuno-protective or toxic?. Environ Sci Pollut Res Int. 2018;25:14813-14826 pubmed publisher
    ..silver nanoparticles (Ag-NPs) incorporated at 0.5 and 1 mg/kg diet and control diet (Ag-NPs at 0 mg/kg). Fish were exposed to sublethal level of 1/25th of LC50 (4 ppm) of lead (Pb) and temperature at 34 °C...
  24. Korf H. Signaling pathways to and from the hypophysial pars tuberalis, an important center for the control of seasonal rhythms. Gen Comp Endocrinol. 2018;258:236-243 pubmed publisher
    ..While the perception of these signals involves extraocular photoreceptors in non-mammalian species (birds, fish), mammals perceive photoperiodic signals exclusively in the retina...
  25. Berti V, Murray J, Davies M, Spector N, Tsui W, Li Y, et al. Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals. J Nutr Health Aging. 2015;19:413-23 pubmed publisher
    ..AD-protective' nutrient combination was associated with higher intake of fresh fruit and vegetables, whole grains, fish and low-fat dairies, and lower intake of sweets, fried potatoes, high-fat dairies, processed meat and butter...
  26. Spagnoli S, Xue L, Kent M. The common neural parasite Pseudoloma neurophilia is associated with altered startle response habituation in adult zebrafish (Danio rerio): Implications for the zebrafish as a model organism. Behav Brain Res. 2015;291:351-360 pubmed publisher
    ..neurophilia infection must be explored. Fish infected via cohabitation were tested for startle response habituation in parallel with controls in a device that ..
  27. Hartig E, Zhu S, King B, Coffman J. Cortisol-treated zebrafish embryos develop into pro-inflammatory adults with aberrant immune gene regulation. Biol Open. 2016;5:1134-41 pubmed publisher
    ..In adulthood the treated fish maintained elevated basal cortisol levels in the absence of exogenous cortisol, and constitutively mis-expressed ..
  28. Nelms M, Hodo W, Rajendran A. A representative volume element based micromechanical analysis of a Bi-layered Ganoid Fish scale. J Mech Behav Biomed Mater. 2017;69:395-403 pubmed publisher
    ..Therefore, to be able to determine the stiffness tensor requires the use of finite element analysis (FEA). The gar fish scale was computationally modeled using the representative volume element (RVE) based approach...
  29. Pisa L, Goulson D, Yang E, Gibbons D, Sanchez Bayo F, Mitchell E, et al. An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems. Environ Sci Pollut Res Int. 2017;: pubmed publisher
    ..Sublethal effects on fish, reptiles, frogs, birds, and mammals are also reported, showing a better understanding of the mechanisms of ..
  30. Bai Y, Zhang J, Sun Q, Zhou J, Luo J, He L, et al. Induction of microRNA-199 by Nitric Oxide in Endothelial Cells is Required for Nitrovasodilator Resistance via Targeting of Prostaglandin I2 Synthase. Circulation. 2018;: pubmed publisher
    ..The expressional levels of miR-199a/b were assayed by RT-qPCR or FISH. Results -In cultured HUVECs, NO donors induced miR-199a/b endogenous expression of and downregulated ..
  31. Hoppe B, Pietsch S, Franke M, Engel S, Groth M, Platzer M, et al. MiR-21 is required for efficient kidney regeneration in fish. BMC Dev Biol. 2015;15:43 pubmed publisher
    ..In contrast, fish are able to generate new nephrons even in adulthood and thus provide a good model to study renal tubular ..
  32. Zhang Q, Xia Z, Wu M, Wang L, Yang H. Human health risk assessment of DDTs and HCHs through dietary exposure in Nanjing, China. Chemosphere. 2017;177:211-216 pubmed publisher in China, the most common consumed 23 kinds of foods from eleven different categories (vegetable, fruit, fish, pork, livestock meat, chicken, egg, milk, oil, rice and flour) were sampled in November 2015...
  33. Du F, Xu G, Li Y, Nie Z, Xu P. Molecular cloning and differential expression of the glucocorticoid receptorgene in the estuarine tapertail anchovy Coilia nasus. Genet Mol Res. 2017;16: pubmed publisher
    To understand the regulation of the glucocorticoid receptor gene (Gcr) during loading and transport stress in fish, the Gcr gene of Coilia nasus was cloned. Gcr in C...
  34. Alexeev N, Alekseyev M. Estimation of the true evolutionary distance under the fragile breakage model. BMC Genomics. 2017;18:356 pubmed publisher
    ..the proposed method for estimation of evolutionary distances within a set of five yeast genomes and a set of two fish genomes...
  35. Nishimura T, Yamada K, Fujimori C, Kikuchi M, Kawasaki T, Siegfried K, et al. Germ cells in the teleost fish medaka have an inherent feminizing effect. PLoS Genet. 2018;14:e1007259 pubmed publisher
    ..Germ cells in medaka may have a potential to feminize gonads at the moment they have developed. ..
  36. Choi K, Weber J. Pushing the limits of glucose kinetics: how rainbow trout cope with a carbohydrate overload. J Exp Biol. 2015;218:2873-80 pubmed publisher
    ..To evaluate this, exogenous glucose was administered to chronically hyperglycemic fish at twice the endogenous rate of hepatic production, and their ability to modulate glucose fluxes was tested...
  37. Wang Y, Wang Y, Hui C, Chen J. Transcriptome analysis of the effect of Vibrio alginolyticus infection on the innate immunity-related TLR5-mediated induction of cytokines in Epinephelus lanceolatus. Fish Shellfish Immunol. 2016;52:31-43 pubmed publisher
    Epinephelus lanceolatus, considered to be an aquaculture fish species of high economic value in East Asia, is one of the largest groupers in the Epinephelus genus...
  38. Zhou T, Li N, Liu S, Jin Y, Fu Q, Gao S, et al. The NCK and ABI adaptor genes in catfish and their involvement in ESC disease response. Dev Comp Immunol. 2017;73:119-123 pubmed publisher
    ..In the liver, NCK2a, NCK2b, ABI1b, ABI2a, ABI2b were significantly upregulated in ESC susceptible fish. In general, the NCK and ABI genes, with exception of ABI3a gene and NCK1 gene, were expressed at higher levels in ..
  39. Chi H, Wen L, Sui Z, Sun Q, Sun L. Cytochemical identification of turbot myeloperoxidase-positive granulocytes by potassium iodide and oxidized pyronine Y staining. Tissue Cell. 2017;49:751-755 pubmed publisher
    ..and cytochemical staining are important methods for the identification of cell types, in particular in fish which often lack biological tools such as specific antibodies...
  40. Fu L, Lu X, Tan J, Wang L, Chen J. Multiresidue determination and potential risks of emerging pesticides in aquatic products from Northeast China by LC-MS/MS. J Environ Sci (China). 2018;63:116-125 pubmed publisher
    ..The results showed that all targeted pesticides were present in the fish samples; however, their levels were low, except for atrazine, linuron, ethoprophos, tetrachlorvinphos, acetochlor ..
  41. Jing H, Gao L, Zhang M, Wang N, Lin X, Zhang L, et al. Establishment from the snout and kidney of goldfish, Carassius auratus, of two new cell lines and their susceptibility to infectious pancreatic necrosis virus. Fish Physiol Biochem. 2016;42:303-11 pubmed publisher
    ..These newly established cell lines will be a useful diagnostic tool for viral diseases in this fish species and also for the isolation and study of goldfish viruses in future.
  42. Lallement M, Macchi P, Vigliano P, Juarez S, Rechencq M, Baker M, et al. Rising from the ashes: Changes in salmonid fish assemblages after 30 months of the Puyehue-Cordon Caulle volcanic eruption. Sci Total Environ. 2016;541:1041-1051 pubmed publisher
    ..In order to analyze changes on stream fish assemblages we studied seven streams 8, 19 and 30 months after the eruption along the ash deposition gradient, and ..
  43. Ali S, Hensing T, Schrock A, Allen J, Sanford E, Gowen K, et al. Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization. Oncologist. 2016;21:762-70 pubmed publisher
    ..ALK break-apart fluorescence in situ hybridization (FISH) is the U.S...
  44. Lanzafame G, Sarakha M, Fabbri D, Vione D. Degradation of Methyl 2-Aminobenzoate (Methyl Anthranilate) by H₂O₂/UV: Effect of Inorganic Anions and Derived Radicals. Molecules. 2017;22: pubmed publisher
    ..Irradiated H₂O₂ is effective in photodegrading MA, but the resulting MA hydroxyderivatives are predicted to be about as toxic as the parent compound for aquatic organisms (most notably, fish and crustaceans).
  45. Li K, Qi Y, Xia T, Chan A, Zhang Z, Aibaidula A, et al. The kinesin KIF14 is overexpressed in medulloblastoma and downregulation of KIF14 suppressed tumor proliferation and induced apoptosis. Lab Invest. 2017;97:946-961 pubmed publisher
    ..0063) and overall survival (P=0.0083). Fluorescence in situ hybridization (FISH) analysis confirmed genomic gain of chromosome 1q in 17/93 (18.3%) of MB...
  46. Kaiser B, Kourantidou M, Fernandez L. A case for the commons: The Snow Crab in the Barents. J Environ Manage. 2018;210:338-348 pubmed publisher
    ..with sound biological and economic information can in theory set overall harvest control rules that protect the fish stocks, and manage for external costs and benefits from harvest...
  47. Jang J, Kim H, Kim Y, Cho J. Molecular cloning and functional analysis of nucleotide-binding oligomerization domain-containing protein 1 in rainbow trout, Oncorhynchus mykiss. Fish Shellfish Immunol. 2016;51:53-63 pubmed publisher
    ..These findings highlight the important role of NOD1 signaling pathway in fish in eliciting innate immune response.
  48. Srebotnik Kirbiš I, Limbäck Stokin C. Application of brush cytology for FISH-based detection of 1p/19q codeletion in oligodendroglial tumors. J Neurooncol. 2016;129:415-422 pubmed publisher
    ..This analysis is most commonly performed by fluorescence in situ hybridization (FISH) on formalin-fixed, paraffin embedded (FFPE) tissue sections, which is time-consuming and often difficult to ..
  49. Liu T, Ma L, Zheng Z, Li F, Liu S, Xie Y, et al. Resveratrol inhibits age-dependent spontaneous tumorigenesis by SIRT1-mediated post-translational modulations in the annual fish Nothobranchius guentheri. Oncotarget. 2017;8:55422-55434 pubmed publisher
    ..Spontaneous liver neoplasm is an age-related disease and is inhibited by resveratrol in the annual fish Nothobranchius guentheri, which indicates that the fish can act as an excellent model to study spontaneous ..
  50. Martin N, Gharib M. On the role of tip curvature on flapping plates. Bioinspir Biomim. 2017;: pubmed publisher
    During the flapping motion of a fish's tail, the caudal fin exhibits antero-posterior bending and dorso-ventral bending, the latter of which is referred to as chord-wise bending herein...
  51. Tuakuila J, Kabamba M, Mata H, Mbuyi F. Tentative reference values for environmental pollutants in blood or urine from the children of Kinshasa. Chemosphere. 2015;139:326-33 pubmed publisher in Kinshasa (6years on average, 56% of girls, 100% of non-smokers, without amalgam fillings and consumers of fish 3 times per week)...
  52. Wang R, Li L, Huang Y, Luo F, Liang W, Gan X, et al. Comparative genome analysis identifies two large deletions in the genome of highly-passaged attenuated Streptococcus agalactiae strain YM001 compared to the parental pathogenic strain HN016. BMC Genomics. 2015;16:897 pubmed publisher group B Streptococcus (GBS), is an important pathogen for neonatal pneumonia, meningitis, bovine mastitis, and fish meningoencephalitis...
  53. Nonga H, Ngowi H, Mdegela R, Mutakyawa E, Nyahinga G, William R, et al. Survey of physicochemical characteristics and microbial contamination in selected food locally vended in Morogoro Municipality, Tanzania. BMC Res Notes. 2015;8:727 pubmed publisher
    Raw milk, raw fruit juice and raw fish are enriched with essential nutrients for human diet but are prone to microbial contamination along the value chain...
  54. Argyris P, Wetzel S, Greipp P, Wehrs R, Knutson D, Kloft Nelson S, et al. Clinical utility of myb rearrangement detection and p63/p40 immunophenotyping in the diagnosis of adenoid cystic carcinoma of minor salivary glands: a pilot study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;121:282-9 pubmed publisher
    ..3) break-apart fluorescence in situ hybridization (FISH) probe. In addition, all cases were immunohistochemically stained with p63 and p40 antibodies...
  55. Minetto D, Volpi Ghirardini A, Libralato G. Saltwater ecotoxicology of Ag, Au, CuO, TiO2, ZnO and C60 engineered nanoparticles: An overview. Environ Int. 2016;92-93:189-201 pubmed publisher
    ..i) some model organisms are overexploited like microalgae and molluscs compared to annelids, echinoderms and fish; ii) underexploited model organisms: mainly bacteria and fish; iii) exposure scenario variability: high species-..
  56. Rodriguez F, Valenzuela B, Farías A, Sandino A, Imarai M. ?-1,3/1,6-Glucan-supplemented diets antagonize immune inhibitory effects of hypoxia and enhance the immune response to a model vaccine. Fish Shellfish Immunol. 2016;59:36-45 pubmed publisher
    ..These effects were also tested on vaccinated fish, as we expected that ?-1,3/1,6-glucan-supplemented diets would enhance the adaptive immune response to the vaccine...
  57. Kalantzi I, Mylona K, Sofoulaki K, Tsapakis M, Pergantis S. Arsenic speciation in fish from Greek coastal areas. J Environ Sci (China). 2017;56:300-312 pubmed publisher
    Arsenic speciation analysis was conducted on fish samples (sardine and anchovy) collected from six areas along the Greek coastline, i.e...
  58. McCormick M. Behaviourally mediated phenotypic selection in a disturbed coral reef environment. PLoS ONE. 2009;4:e7096 pubmed publisher
    ..Recently settled fish had a low propensity to migrate small distances (40 cm) between habitat patches, even when densities were elevated ..
  59. Shao L, Miller S, Keller Ramey J, Zhang Y, Roulston D. Cytogenetic, fluorescence in situ hybridization, and genomic array characterization of chronic myeloid leukemia with cryptic BCR-ABL1 fusions. Cancer Genet. 2015;208:396-403 pubmed publisher
    ..of five CML patients with cryptic BCR-ABL1 fusion genes using karyotype, fluorescence in situ hybridization (FISH), and whole genome single nucleotide polymorphism array techniques...
  60. Wang X, Yin D, Li P, Yin S, Wang L, Jia Y, et al. MicroRNA-Sequence Profiling Reveals Novel Osmoregulatory MicroRNA Expression Patterns in Catadromous Eel Anguilla marmorata. PLoS ONE. 2015;10:e0136383 pubmed publisher
    ..Recently, several miRNAs have been confirmed to execute directly or indirectly osmoregulatory functions in fish via translational control...
  61. Le Bris Y, Struski S, Guieze R, Rouvellat C, Prade N, Troussard X, et al. Major prognostic value of complex karyotype in addition to TP53 and IGHV mutational status in first-line chronic lymphocytic leukemia. Hematol Oncol. 2016;: pubmed publisher
    ..Conventional karyotyping therefore appears to be of value, CK being an additional factor, undetectable in classical FISH, in patients with CLL at the stage when therapy becomes required.
  62. Shago M. Recurrent Cytogenetic Abnormalities in Acute Lymphoblastic Leukemia. Methods Mol Biol. 2017;1541:257-278 pubmed
    ..This chapter overviews the major recurrent categories of cytogenetic abnormalities associated with ALL, with an emphasis on the detection and characterization of these cases by G-band and FISH analyses.
  63. Ke Q, Weaver W, Pore A, Gorgoglione B, WILDSCHUTTE J, Xiao P, et al. Role of Viral Hemorrhagic Septicemia Virus Matrix (M) Protein in Suppressing Host Transcription. J Virol. 2017;91: pubmed publisher
    Viral hemorrhagic septicemia virus (VHSV) is a pathogenic fish rhabdovirus found in discrete locales throughout the Northern Hemisphere...
  64. Pelli M, Connaughton V. Chronic exposure to environmentally-relevant concentrations of fluoxetine (Prozac) decreases survival, increases abnormal behaviors, and delays predator escape responses in guppies. Chemosphere. 2015;139:202-9 pubmed publisher
    ..control fish. The effects of fish gender and the presence of a group/school on escape responses were also determined...
  65. Hou Y, Yao K, Yin Y, Wu G. Endogenous Synthesis of Amino Acids Limits Growth, Lactation, and Reproduction in Animals. Adv Nutr. 2016;7:331-42 pubmed publisher
    ..Pro; 4) lactating cows cannot obtain maximum milk protein production without a postruminal supply of Gln or Pro; 5) fish cannot achieve maximum growth when diets do not contain Gln or Pro; and 6) men fail to sustain spermatogenesis when ..
  66. GAUTHIER J, Charette S, Derome N. Draft Genome Sequence of Pseudomonas fluorescens ML11A, an Endogenous Strain from Brook Charr with Antagonistic Properties against Aeromonas salmonicida subsp. salmonicida. Genome Announc. 2017;5: pubmed publisher
    ..i>salmonicida, a bacterial fish pathogen...
  67. Esbaugh A. Physiological implications of ocean acidification for marine fish: emerging patterns and new insights. J Comp Physiol B. 2018;188:1-13 pubmed publisher
    ..Numerous detrimental effects have been documented in marine fish, ranging from reduced mortality to neurosensory impairment, and the prevailing opinions state that these effects ..
  68. Amaral D, Montalvão M, Mendes B, de Souza J, Chagas T, Rodrigues A, et al. Insights about the toxic effects of tannery effluent on Lithobates catesbeianus tadpoles. Sci Total Environ. 2018;621:791-801 pubmed publisher
    ..Although previous studies have already shown the consequences from fish, birds and mammals' exposure to this pollutant, little is known about its toxicological effect on representatives ..
  69. Li C, Ren Y, Jiang S, Zhou S, Zhao J, Wang R, et al. Effects of dietary supplementation of four strains of lactic acid bacteria on growth, immune-related response and genes expression of the juvenile sea cucumber Apostichopus japonicus Selenka. Fish Shellfish Immunol. 2018;74:69-75 pubmed publisher
    ..Weissella confuse LS13 (WC), Lactococcus lactis LH8 (LL) and Enterococcus faecalis LC3 (ES)] isolated from marine fish on growth, immune response and expression levels of immune-related gens in body wall of juvenile sea cucumber ..
  70. Cong M, Wang J, Fang Y, Liu Y, Sun M, Wu Q, et al. A multi-center survey on dietary knowledge and behavior among inpatients in oncology department. Support Care Cancer. 2018;26:2285-2292 pubmed publisher
    ..1%. Importantly, 99.6% of patients have made mistakes about dietary knowledge, for example, crab, chicken, lamb, fish, and prawns should not be eaten in their concept...
  71. Martin S, Cribb T, Cutmore S, Huston D. The phylogenetic position of Choerodonicola Cribb, 2005 (Digenea: Opecoelidae) with a partial life-cycle for a new species from the blue-barred parrotfish Scarus ghobban Forsskål (Scaridae) in Moreton Bay, Australia. Syst Parasitol. 2018;95:337-352 pubmed publisher
    ..gastropod Herpetopoma atratum (Gmelin) (Vetigastropoda: Chilodontidae) collected in close proximity to the fish hosts. Notably, the cercariae lack a penetration stylet and are among the smallest known in the Opecoelidae...
  72. Mizukami T, Togashi Y, Naruki S, Banno E, Terashima M, De Velasco M, et al. Significance of FGF9 gene in resistance to anti-EGFR therapies targeting colorectal cancer: A subset of colorectal cancer patients with FGF9 upregulation may be resistant to anti-EGFR therapies. Mol Carcinog. 2017;56:106-117 pubmed publisher
    ..FGF9 amplification was validated using a fluorescence in situ hybridization (FISH) analysis, and FGF9-amplified sections showed readily detectable signals originating from FGF9 protein when ..
  73. Holtzman N, Iovine M, Liang J, Morris J. Learning to Fish with Genetics: A Primer on the Vertebrate Model Danio rerio. Genetics. 2016;203:1069-89 pubmed publisher
    ..This primer describes the swift progress of genetic approaches in zebrafish and highlights recent advances that have led to new insights into vertebrate biology. ..
  74. Karafiátová M, Bartos J, Dolezel J. Localization of Low-Copy DNA Sequences on Mitotic Chromosomes by FISH. Methods Mol Biol. 2016;1429:49-64 pubmed publisher
    Fluorescence in situ hybridization (FISH) is a widely used method to localize DNA sequences on mitotic and meiotic chromosomes and interphase nuclei...
  75. Caliò A, Bria E, Pilotto S, Gilioli E, Nottegar A, Eccher A, et al. ALK gene copy number in lung cancer: Unspecific polyploidy versus specific amplification visible as double minutes. Cancer Biomark. 2017;18:215-220 pubmed publisher
    ..The locus specific ALK copy (LSI) number status was evaluated in 205 cases by FISH. Ratio LSI ALK copy number corrected for control probes CEP2, CEP3 and CEP17 (CEPs) was scored...
  76. Koganti P, Wang J, Cleveland B, Yao J. 17?-Estradiol Increases Non-CpG Methylation in Exon 1 of the Rainbow Trout (Oncorhynchus mykiss) MyoD Gene. Mar Biotechnol (NY). 2017;19:321-327 pubmed publisher
    ..The percent methylation of the targeted CpG did not differ between control and E2-treated fish. However, percent CpH methylation in the MyoD exon 1 region was elevated with E2 treatment...
  77. Castelló A, Boldo E, Amiano P, Castano Vinyals G, Aragones N, Gomez Acebo I, et al. Mediterranean Dietary Pattern is Associated with Low Risk of Aggressive Prostate Cancer: MCC-Spain Study. J Urol. 2018;199:430-437 pubmed publisher
    ..High adherence to a Mediterranean dietary pattern rich not only in fruits and vegetables but also in fish, legumes and olive oil was specifically associated with a lower risk of Gleason score greater than 6 prostate ..
  78. Feng C, Xu S, Liu Y, Wang Y, Wang W, Yang J, et al. Progestin is important for testicular development of male turbot (Scophthalmus maximus) during the annual reproductive cycle through functionally distinct progestin receptors. Fish Physiol Biochem. 2018;44:35-48 pubmed publisher
    ..Furthermore, males with higher motility sperm showed higher levels of P4 and DHP compared with fish with lower motility sperm...
  79. Wu J, Shi Y, Zhang X, Li C, Li M, Chen J. Molecular characterization of an IL-1β gene from the large yellow croaker (Larimichthys crocea) and its effect on fish defense against Vibrio alginolyticus infection. Dongwuxue Yanjiu. 2015;36:133-41 pubmed
    ..These results suggest that LcIL-1β plays an important role in the large yellow croaker immune response against V. alginolyticus. ..
  80. Souza U, Ferreira F, Carmo M, Braga F. Feeding and reproductive patterns of Astyanax intermedius in a headwater stream of Atlantic Rainforest. An Acad Bras Cienc. 2015;87:2151-62 pubmed publisher
    ..We also evaluated the influence of rainfall, water temperature and fish size on niche width and niche overlap...
  81. Zheng J, Yuan S, Shen B, Wu C. Organ-specific effects of low-dose zinc pre-exposure on high-dose zinc induced mitochondrial dysfunction in large yellow croaker Pseudosciaena crocea. Fish Physiol Biochem. 2017;43:653-661 pubmed publisher
    ..To the end, fish were pre-exposed to 0 and 2 mg L-1 Zn for 48 h and post-exposed to 0 and 12 mg L-1 Zn ..
  82. Li X, Xu C, Jiang G, Zhang D, Liu W. Molecular characterization of fructose-1,6-bisphosphatase 1b in blunt snout bream Megalobrama amblycephala and the transcriptional response to glucose loading after the adaptation to high-carbohydrate diets. Fish Physiol Biochem. 2017;43:1337-1349 pubmed publisher aimed to characterize the full-length complementary DNA (cDNA) of fructose-1,6-bisphosphatase 1b (FBP1b) from fish Megalobrama amblycephala, and investigate its transcriptional response to glucose administration after the ..
  83. Kadota M, Hara Y, Tanaka K, Takagi W, Tanegashima C, Nishimura O, et al. CTCF binding landscape in jawless fish with reference to Hox cluster evolution. Sci Rep. 2017;7:4957 pubmed publisher
    ..Our study provides not only biological insights into the antiquity of CTCF-based epigenomic regulation known in mammals but also a technical basis for comparative epigenomic studies encompassing the whole taxon Vertebrata. ..
  84. Colin N, Maceda Veiga A, Monroy M, Ortega Ribera M, Llorente M, De Sostoa A. Trends in biomarkers, biotic indices, and fish population size revealed contrasting long-term effects of recycled water on the ecological status of a Mediterranean river. Ecotoxicol Environ Saf. 2017;145:340-348 pubmed publisher has ecological risk, as suggested by comparison of habitat and white and red blood cell count in two wild fish species (Barbus meridionalis and Squalius laietanus) before and after an input of recycled water in Ripoll River (..
  85. He P, Wang W, Sanogo B, Zeng X, Sun X, Lv Z, et al. Molluscicidal activity and mechanism of toxicity of a novel salicylanilide ester derivative against Biomphalaria species. Parasit Vectors. 2017;10:383 pubmed publisher
    ..125 mg/l for niclosamide. However, salicylanilidate was approximately 100-fold less toxic to the fish Danio rerio than niclosamide...
  86. Yan Y, Ma M, Liu X, Ma W, Li Y. Vertical distribution of archaeal communities associated with anaerobic degradation of pentabromodiphenyl ether (BDE-99) in river-based groundwater recharge with reclaimed water. Environ Sci Pollut Res Int. 2018;25:5154-5163 pubmed publisher
    ..concentration of BDE-99 decreased significantly as soil depth increased, and fluorescence in situ hybridization (FISH) analysis suggested that archaea exerted significant effects on the biodegradation of PBDE...
  87. Rasheed M, Ahmed M, Hassan A, Nazim U, Khan R, Kamal M, et al. Bile acids and bile alcohols from Muraenesox bagio, Pomadasys argenteus and Lobeo rohita. Pak J Pharm Sci. 2017;30:1759-1765 pubmed
    Gallbladders bile of three well known commercial fish of South Asia region named Muraenesox bagio (locally called bam), Pomadasys argenteus (dother) and Lobeo rohita (rohu) were analysed on GC-MS, after derivatising the bile alcohols and ..
  88. Wang X, Chu Z, Yang J, Li Y. Pentachlorophenol molecule design with lower bioconcentration through 3D-QSAR associated with molecule docking. Environ Sci Pollut Res Int. 2017;24:25114-25125 pubmed publisher
    ..technique with an experimentally determined logarithm of bioconcentration factors (logBCFs) for 36 phenols in fish. Meanwhile, with the pentachlorophenol (PCP) molecule as target molecules, contributions of the molecular fields ..
  89. Kleppe L, Andersson E, Skaftnesmo K, Edvardsen R, Fjelldal P, Norberg B, et al. Sex steroid production associated with puberty is absent in germ cell-free salmon. Sci Rep. 2017;7:12584 pubmed publisher
    ..No GCF fish entered puberty, whereas 66.7% (males) and 30% (females) WT fish completed or entered puberty, respectively...
  90. Roberti G, Cangelose C, Martindale R. Composite Intravenous Fat Emulsion in a Postsurgical Critically Ill Patient: A Case Study. JPEN J Parenter Enteral Nutr. 2017;:148607117743494 pubmed publisher
    ..b>Fish oil (FO) is generally less inflammatory and has recently been shown to be active in the resolution of inflammatory ..
  91. Li X, Zhang Q, Zhang J, Zhou L, Li Z, Zhang X, et al. Extra Microchromosomes Play Male Determination Role in Polyploid Gibel Carp. Genetics. 2016;203:1415-24 pubmed publisher
    ..Subsequently, we have found through FISH analysis that males have several extra microchromosomes with repetitive sequences and transposable elements when ..
  92. Butler L, Janulewicz P, Carwile J, White R, Winter M, Aschengrau A. Childhood and adolescent fish consumption and adult neuropsychological performance: An analysis from the Cape Cod Health Study. Neurotoxicol Teratol. 2017;61:47-57 pubmed publisher
    This exploratory analysis examines the relationship between childhood and adolescent fish consumption and adult neuropsychological performance...