SGCA

Summary

Gene Symbol: SGCA
Description: sarcoglycan alpha
Alias: 50DAG, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin, alpha-sarcoglycan, 50 kDa dystrophin-associated glycoprotein, 50kD DAG, alpha-SG, dystroglycan-2, limb girdle muscular dystrophy 2D, sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Species: human
Products:     SGCA

Top Publications

  1. Yang B, Jung D, Motto D, Meyer J, Koretzky G, Campbell K. SH3 domain-mediated interaction of dystroglycan and Grb2. J Biol Chem. 1995;270:11711-4 pubmed
    ..The specific dystroglycan-Grb2 interaction may play an important role in extracellular matrix-mediated signal transduction and/or cytoskeleton organization in skeletal muscle that may be essential for muscle cell viability. ..
  2. Roberds S, Leturcq F, Allamand V, Piccolo F, Jeanpierre M, Anderson R, et al. Missense mutations in the adhalin gene linked to autosomal recessive muscular dystrophy. Cell. 1994;78:625-33 pubmed
    b>Adhalin, the 50 kDa dystrophin-associated glycoprotein, is deficient in skeletal muscle of patients having severe childhood autosomal recessive muscular dystrophy (SCARMD)...
  3. Roberds S, Anderson R, Ibraghimov Beskrovnaya O, Campbell K. Primary structure and muscle-specific expression of the 50-kDa dystrophin-associated glycoprotein (adhalin). J Biol Chem. 1993;268:23739-42 pubmed
    ..Finally, 50-DAG mRNA is present in mdx and Duchenne muscular dystrophy (DMD) muscle, indicating that the down-regulation of this protein in DMD and the mdx mouse is likely a post-translational event. ..
  4. Carrie A, Piccolo F, Leturcq F, de Toma C, Azibi K, Beldjord C, et al. Mutational diversity and hot spots in the alpha-sarcoglycan gene in autosomal recessive muscular dystrophy (LGMD2D). J Med Genet. 1997;34:470-5 pubmed
    ..in any of the genes coding for the different partners of the sarcolemmal sarcoglycan (SG) complex: the alpha-SG (LGMD2D at 17q21.2), the beta-SG (LGMD2E at 4q12), the gamma-SG (LGMD2C at 13q12), and the delta-SG (LGMD2F at 5q33)...
  5. Bowe M, Mendis D, Fallon J. The small leucine-rich repeat proteoglycan biglycan binds to alpha-dystroglycan and is upregulated in dystrophic muscle. J Cell Biol. 2000;148:801-10 pubmed
    ..These results also raise the possibility of a role for biglycan in the pathogenesis, and perhaps the treatment, of muscular dystrophy. ..
  6. Li C, Li L, Yang C, Zhong Y, Wu D, Shi L, et al. Hepatoprotective effects of Methyl ferulic acid on alcohol-induced liver oxidative injury in mice by inhibiting the NOX4/ROS-MAPK pathway. Biochem Biophys Res Commun. 2017;493:277-285 pubmed publisher
    ..and low-density lipoprotein (LDL), decreasing the levels of high-density lipoprotein (HDL), alcohol dehydrogenase(ADL) and aldehyde dehydrogenase (ALDH)...
  7. Bian K, Jin H, Sun W, Sun Y. DCA can improve the ACI-induced neurological impairment through negative regulation of Nrf2 signaling pathway. Eur Rev Med Pharmacol Sci. 2019;23:343-351 pubmed publisher
    ..decrease the National Institute of Health Stroke Scale (NIHSS) score but increase the activity of daily living (ADL) score of patients, and significantly reduce the content of serum TG, TC, and LDL-C, showing statistically ..
  8. Mojbafan M, Nilipour Y, Tonekaboni S, Tavakkoly Bazzaz J, Zeinali S. A novel mutation in alpha sarcoglycan gene in an Iranian family with limb girdle muscular dystrophy 2D. Neurol Res. 2016;38:220-3 pubmed publisher
    ..repeat (STR) markers linked to the SG genes, showed co-segregation of the phenotype with STR markers linked to the SGCA (Alpha-sarcoglycan) gene. Her muscle biopsy also suggested alpha sarcoglycanopathy...
  9. Suriyonplengsaeng C, Dejthevaporn C, Khongkhatithum C, Sanpapant S, Tubthong N, Pinpradap K, et al. Immunohistochemistry of sarcolemmal membrane-associated proteins in formalin-fixed and paraffin-embedded skeletal muscle tissue: a promising tool for the diagnostic evaluation of common muscular dystrophies. Diagn Pathol. 2017;12:19 pubmed publisher
    ..become a valuable tool for the diagnosis of some muscular dystrophies, dystrophinopathies, sarcoglycanopathies (LGMD2D, LGMD2E, and LGMD2C), and dysferlinopathy, especially in situations where the analysis of fresh frozen muscle ..

More Information

Publications144 found, 100 shown here

  1. Madabhavi I, Revannasiddaiah S, Sarkar M, Modi M. Sanctuary site central nervous system relapse-refractory DLBCL responding to nivolumab and lenalidomide. Oral Oncol. 2019;: pubmed publisher
    ..He was able to manage his daily ADL and able to walk with a stick...
  2. Tasca G, Monforte M, Diaz Manera J, Brisca G, Semplicini C, D Amico A, et al. MRI in sarcoglycanopathies: a large international cohort study. J Neurol Neurosurg Psychiatry. 2018;89:72-77 pubmed publisher
    ..Scans from 69 patients were examined (38 LGMD2D, 18 LGMD2C, 12 LGMD2E and 1 LGMD2F)...
  3. Tsolaki M, Zygouris S, Lazarou I, Kompatsiaris I, Chatzileontiadis L, Votis C, et al. Our experience with informative and communication technologies (ICT) in dementia. Hell J Nucl Med. 2015;18 Suppl 1:131-9 pubmed
    ..which are appropriately adapted in order to capture changes of subject's Activities of Daily Living -ADL- and behavioural patterns (including mobility, nutrition, exercising and medication schedule)...
  4. Han P, Zhang W, Kang L, Ma Y, Fu L, Jia L, et al. Clinical Evidence of Exercise Benefits for Stroke. Adv Exp Med Biol. 2017;1000:131-151 pubmed publisher
    ..Neuromuscular exercises can improve activities of daily living (ADL) through coordination and balance activities...
  5. Arokiasamy P, Uttamacharya U, Jain K, Biritwum R, Yawson A, Wu F, et al. The impact of multimorbidity on adult physical and mental health in low- and middle-income countries: what does the study on global ageing and adult health (SAGE) reveal?. BMC Med. 2015;13:178 pubmed publisher
    ..Associations with four health outcomes were examined, namely ADL limitation, self-rated health, depression, and a quality of life index...
  6. Avelino Silva T, Farfel J, Curiati J, Amaral J, Campora F, Jacob Filho W. Comprehensive geriatric assessment predicts mortality and adverse outcomes in hospitalized older adults. BMC Geriatr. 2014;14:129 pubmed publisher
    ..Impairment in ten CGA components was particularly investigated: polypharmacy, activities of daily living (ADL) dependency, instrumental activities of daily living (IADL) dependency, depression, dementia, delirium, urinary ..
  7. Gerbert C, Frieten D, Koch C, Dusel G, Eder K, Stefaniak T, et al. Effects of ad libitum milk replacer feeding and butyrate supplementation on behavior, immune status, and health of Holstein calves in the postnatal period. J Dairy Sci. 2018;101:7348-7360 pubmed publisher
    ..Holstein calves (n = 64) were examined from birth until wk 11 of age. Calves received MR either ad libitum (Adl) or restrictively (Res) with (AdlB+, ResB+) or without (AdlB-, ResB-) 0...
  8. Hagenaars T, van Oijen G, Roerdink W, Vegt P, Vroemen J, Verhofstad M, et al. Functional recovery after treatment of extra-articular distal radius fractures in the elderly using the IlluminOss® System (IO-Wrist); a multicenter prospective observational study. BMC Musculoskelet Disord. 2016;17:235 pubmed publisher
    ..Because IlluminOss® allows for early mobilization, it may theoretically lead to earlier functional recovery and ADL independence than non-operative immobilization...
  9. Isogai T, Matsui H, Tanaka H, Fushimi K, Yasunaga H. In-hospital Takotsubo syndrome versus in-hospital acute myocardial infarction among patients admitted for non-cardiac diseases: a nationwide inpatient database study. Heart Vessels. 2019;: pubmed publisher
    ..5 vs. 32.9%) and underweight (24.8 vs. 14.1%) and were more likely to have had impaired activities of daily living (ADL) and impaired consciousness than those with AMI...
  10. Allami M, Yavari A, Karimi A, Masoumi M, Soroush M, Faraji E. Health-related quality of life and the ability to perform activities of daily living: a cross-sectional study on 1079 war veterans with ankle-foot disorders. Mil Med Res. 2017;4:37 pubmed publisher
    ..The ability to perform daily activities was assessed using the Barthel activities of daily living (ADL) and Lawton instrumental activities of daily living (IADL) Indexes...
  11. Lamb R, Rohrer J, Lees A, Morris H. Progressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment Options. Curr Treat Options Neurol. 2016;18:42 pubmed publisher
    ..on optimizing quality of life, relieving symptoms and assisting patients with their activities of daily living (ADL)...
  12. Meddings J, Reichert H, Smith S, Iwashyna T, Langa K, Hofer T, et al. The Impact of Disability and Social Determinants of Health on Condition-Specific Readmissions beyond Medicare Risk Adjustments: A Cohort Study. J Gen Intern Med. 2017;32:71-80 pubmed publisher
    ..HRS-CMS models included disability measures (activities of daily living [ADL] limitations, cognitive impairment, nursing home residence, home healthcare use) and social determinants of health (..
  13. Hosseini M, Allami M, Soroush M, Babaha F, Minooeefar J, Rahimpoor D. Chronic traumatic ankle and foot osteomyelitis: a nationwide case-control study. Mil Med Res. 2018;5:15 pubmed publisher
    ..questionnaires: short-form health survey (SF-36), satisfaction with life scale (SWLS), activity of daily living (ADL) and instrumental activity of daily living (IADL), respectively...
  14. Sutcliffe C, Giebel C, Bleijlevens M, Lethin C, Stolt M, Saks K, et al. Caring for a Person With Dementia on the Margins of Long-Term Care: A Perspective on Burden From 8 European Countries. J Am Med Dir Assoc. 2017;18:967-973.e1 pubmed publisher
    ..scale), comorbidity (Charlson Comorbidity Index), and physical functioning (Katz Activity of Daily Living [ADL] Index)...
  15. Shrestha B, Kim B, Huffstetler A. An unusual presentation of gastric mucosa-associated lymphoid tissue (MALT)-type lymphoma. J Community Hosp Intern Med Perspect. 2016;6:31707 pubmed publisher
    ..fatigue for 3 months which had progressed to the point of hindering his usual activities of daily living (ADL)...
  16. Fritz J, Inawat R, Slavens B, McGuire J, Ziegler D, Tarima S, et al. Assessment of Kinematics and Electromyography Following Arthroscopic Single-Tendon Rotator Cuff Repair. PM R. 2017;9:464-476 pubmed publisher
    ..Although limited abduction was expected due to repair of the supraspinatus tendon, only a single ADL (reaching to back pocket) had a significantly reduced abduction range of motion...
  17. Spannella F, Giulietti F, Cocci G, Landi L, Lombardi F, Borioni E, et al. Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Oldest Adults: Predictors of In-Hospital Mortality and Need for Post-acute Care. J Am Med Dir Assoc. 2019;: pubmed publisher
    ..Activities of Daily Living (ADL) Hierarchy scale, Geriatric Index of Comorbidity, cognitive impairment, and clinical and laboratory parameters were ..
  18. Peng C, Wang X, Li S, Liu Z, Sun T, Zhang J. [Effect of hip fracture at different sites in elderly patients on prognosis]. Zhongguo Gu Shang. 2017;30:906-910 pubmed publisher
    ..In patients who survived, the scores of ADL for femoral neck fracture were higher than that of intertrochanteric fracture at discharge, 1, 3 months after ..
  19. Szczerbińska K, Topinková E, Brzyski P, van der Roest H, Richter T, Finne Soveri H, et al. The characteristics of diabetic residents in European nursing homes: results from the SHELTER study. J Am Med Dir Assoc. 2015;16:334-40 pubmed publisher
    ..28; 95% CI -0.41 to -0.14; P < .001). DM was not associated with ADL dependency, cognitive impairment, and depression in NH residents...
  20. Gauthier S, Feldman H, Schneider L, Wilcock G, Frisoni G, Hardlund J, et al. Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial. Lancet. 2016;388:2873-2884 pubmed publisher
    ..Subscale (ADAS-Cog) and the Alzheimer's Disease Co-operative Study-Activities of Daily Living Inventory (ADCS-ADL) scales from baseline assessed at week 65 in the modified intention-to-treat population...
  21. Cummings J, Atri A, Ballard C, Boneva N, Frolich L, Molinuevo J, et al. Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer's disease clinical program. Alzheimers Res Ther. 2018;10:116 pubmed publisher
    ..2 in South America/Mexico. Baseline AD Cooperative Study-Activities of Daily Living, 23-item version (ADCS-ADL23) scores ranged from 58.5 in USA/Canada to 53.5 in Eastern Europe/Turkey...
  22. Phuti A, Schneider M, Makan K, Tikly M, Hodkinson B. Living with systemic lupus erythematosus in South Africa: a bitter pill to swallow. Health Qual Life Outcomes. 2019;17:65 pubmed publisher
    ..Living with pain was the most common complaint, negatively impacting on activities of daily living (ADL), family expectations, social life, sleep and intimacy...
  23. Kańtoch A, Gryglewska B, Wójkowska Mach J, Heczko P, Grodzicki T. Treatment of Cardiovascular Diseases Among Elderly Residents of Long-term Care Facilities. J Am Med Dir Assoc. 2018;19:428-432 pubmed publisher
    ..Mini Nutritional Assessment Short-Form (MNA-SF), Abbreviated Mental Test Score (AMTS), Activities of Daily Living (ADL) score, and Barthel Index...
  24. Sims Gould J, Tong C, Wallis Mayer L, Ashe M. Reablement, Reactivation, Rehabilitation and Restorative Interventions With Older Adults in Receipt of Home Care: A Systematic Review. J Am Med Dir Assoc. 2017;18:653-663 pubmed publisher
    ..abilities, strength, gait speed, social support, loneliness, and the execution of activities of daily living (ADL) and instrumental ADL (IADL). 4R interventions are intended to reduce the long-term use of home care services...
  25. Hirani V, Naganathan V, Blyth F, Le Couteur D, Gnjidic D, Stanaway F, et al. Multiple, but not traditional risk factors predict mortality in older people: the Concord Health and Ageing in Men Project. Age (Dordr). 2014;36:9732 pubmed publisher
    ..diseases, physical performance measures, blood pressure, height and weight, disability (activities of daily living (ADL) and instrumental ADLs, instrumental ADLs (IADLs)), cognitive status, depressive symptoms and blood analyte ..
  26. Ishigaki K, Murakami T, Ito Y, Yanagisawa A, Kodaira K, Shishikura K, et al. [Treatment approach to congenital myasthenic syndrome in a patient with acetylcholine receptor deficiency]. No To Hattatsu. 2009;41:37-42 pubmed
    ..The patient experienced no side effects. Despite all of the objective data were improving, his subjective symptoms and ADL remained poor. There are still many challenges in the treatment of the patient.
  27. Li H, Guo J, Wang A, Zhang D, Luo Y, Wang W, et al. Assessment of risk factors for cerebrovascular disease among the elderly in Beijing: A 23-year community-based prospective study in China. Arch Gerontol Geriatr. 2018;79:39-44 pubmed publisher
    ..In addition, biochemical parameters, the Activities of Daily Living (ADL) scale, Center for Epidemiological Studies Depression (CES-D) scale, and Mini-Mental State Examination (MMSE) were ..
  28. Tufanin A, Souza G, Tisi G, Tufik S, de Mello M, Nascimento O, et al. Cardiac, ventilatory, and metabolic adjustments in chronic obstructive pulmonary disease patients during the performance of Glittre activities of daily living test. Chron Respir Dis. 2014;11:247-55 pubmed publisher
    ..The Glittre-ADL test was developed to evaluate the functional status of COPD patients and their ability to perform activities of ..
  29. Schrijver E, de Vries O, Verburg A, de Graaf K, Bet P, van de Ven P, et al. Efficacy and safety of haloperidol prophylaxis for delirium prevention in older medical and surgical at-risk patients acutely admitted to hospital through the emergency department: study protocol of a multicenter, randomised, double-blind, placebo-co. BMC Geriatr. 2014;14:96 pubmed publisher
    ..mortality; new institutionalisation; (Instrumental) Activities of Daily Living assessed with the Katz Index of ADL, and Lawton IADL scale; cognitive function assessed with the Six-item Cognitive Impairment Test, and the Dutch ..
  30. Lin J, Lin L, Hsu S, Chen W, Lin F, Wu J, et al. Are early onset aging conditions correlated to daily activity functions in youth and adults with Down syndrome?. Res Dev Disabil. 2015;36C:532-536 pubmed publisher
    ..Screening Questionnaire for Individuals with Intellectual Disabilities (DSQIID) and activity of daily living (ADL) scales were completed by the primary caregivers who were well-suited for providing information on the functioning ..
  31. Kawasaki M, Arai Y, Takayama M, Hirata T, Takayama M, Abe Y, et al. Carotid atherosclerosis, cytomegalovirus infection, and cognitive decline in the very old: a community-based prospective cohort study. Age (Dordr). 2016;38:29 pubmed publisher
    ..using linear regression, carotid atherosclerosis, smoking, low grip strength, and poor activities of daily living (ADL) status were associated with faster cognitive decline, adjusted for age, sex, education, and baseline cognitive ..
  32. Gine Garriga M, Roquè Fíguls M, Coll Planas L, Sitjà Rabert M, Salva A. Physical exercise interventions for improving performance-based measures of physical function in community-dwelling, frail older adults: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2014;95:753-769.e3 pubmed publisher
    ..adults, defined as frail according to physical function and physical difficulties in activities of daily living (ADL)...
  33. Nef T, Urwyler P, Büchler M, Tarnanas I, Stucki R, Cazzoli D, et al. Evaluation of Three State-of-the-Art Classifiers for Recognition of Activities of Daily Living from Smart Home Ambient Data. Sensors (Basel). 2015;15:11725-40 pubmed publisher
    ..One of the problems of interest is to monitor the activities of daily living (ADL) of the elderly, aiming at their protection and well-being...
  34. Muñoz M, Real J, Del Val J, Vinyoles E, Mundet X, Frigola Capell E, et al. Determinants of survival and hospitalization in older, heart failure patients receiving home healthcare. Int J Cardiol. 2016;207:145-9 pubmed publisher
    ..29 95%CI 1.05-1.60), and severe dependence in activities for daily living (ADL) (HR 1.33, 95%CI 1.06-1.67)...
  35. Moussa C, Hebron M, Huang X, Ahn J, Rissman R, Aisen P, et al. Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease. J Neuroinflammation. 2017;14:1 pubmed publisher
    ..to 1 g by mouth twice daily) attenuates progressive declines in CSF Aβ40 levels and activities of daily living (ADL) scores...
  36. Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel J. Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study. Lancet. 2017;389:1619-1629 pubmed publisher
    ..Four health outcomes were investigated: annual death rate, Activities of Daily Living (ADL), physical performance in three tests and cognitive function measured by Mini-Mental State Examination (MMSE)...
  37. Na L, Pan Q, Xie D, Kurichi J, Streim J, Bogner H, et al. Activity Limitation Stages Are Associated With Risk of Hospitalization Among Medicare Beneficiaries. PM R. 2017;9:433-443 pubmed publisher
    ..The hazard ratios (95% confidence intervals) for ADL stages I-IV compared with stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2...
  38. Rosenblum S, Waissman P, Diamond G. Identifying play characteristics of pre-school children with developmental coordination disorder via parental questionnaires. Hum Mov Sci. 2017;53:5-15 pubmed publisher
    ..motor and executive control as reflected in their daily function as well as their activities of daily living (ADL) performance level, contributed to the prediction of their global play participation...
  39. Takahashi S, Hoshino M, Tsujio T, Terai H, Suzuki A, Namikawa T, et al. Risk factors for cognitive decline following osteoporotic vertebral fractures: A multicenter cohort study. J Orthop Sci. 2017;22:834-839 pubmed publisher
    ..fractures (OVFs) are the most common cause of intractable back pain and reduced activities of daily living (ADL), which may affect cognitive function...
  40. Sochacki K, Jack R, Bekhradi A, Delgado D, McCulloch P, Harris J. Are Self-Reported Medication Allergies Associated With Worse Hip Outcome Scores Prior to Hip Arthroscopy?. Arthroscopy. 2018;34:1856-1861 pubmed publisher
    ..188; P < .001). SF-12 Mental Component Score (MCS) was significantly correlated with HOS-ADL (Pearson correlation coefficient, 0.389; P < .001), HOS-SSS (Pearson correlation coefficient, 0.251; P < ...
  41. Fernandez K, Serinagaoglu Y, Hammond S, Martin L, Martin P. Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts. Am J Pathol. 2010;176:416-34 pubmed publisher
    ..Here we show that loss of either of two members of this complex, dystrophin in mdx mice or alpha sarcoglycan in Sgca(-/-) mice, results in the spontaneous development of muscle-derived embryonal rhabdomyosarcoma (RMS) ..
  42. Ulutas O, Farragher J, Chiu E, Cook W, Jassal S. Functional Disability in Older Adults Maintained on Peritoneal Dialysis Therapy. Perit Dial Int. 2016;36:71-8 pubmed publisher
    ..care, we hypothesized that a relatively low number of PD patients would require help with basic self-care tasks (ADL) and instrumental activities of daily living (IADL)...
  43. Chandrasekaran S, Gui C, Darwish N, Lodhia P, Suárez Ahedo C, Domb B. Outcomes of Hip Arthroscopic Surgery in Patients With Tönnis Grade 1 Osteoarthritis With a Minimum 2-Year Follow-up: Evaluation Using a Matched-Pair Analysis With a Control Group With Tönnis Grade 0. Am J Sports Med. 2016;44:1781-8 pubmed publisher
    ..51; Nonarthritic Hip Score (NAHS), 20.65; Hip Outcome Score-Activities of Daily Living (HOS-ADL), 16.83; and Hip Outcome Score-Sport-Specific Subscale (HOS-SSS), 20.91...
  44. Yasuda E, Suzuki Y, Shimada T, Sawamoto K, MacKenzie W, Theroux M, et al. Activity of daily living for Morquio A syndrome. Mol Genet Metab. 2016;118:111-22 pubmed publisher
    The aim of this study was to evaluate the activity of daily living (ADL) and surgical interventions in patients with mucopolysaccharidosis IVA (MPS IVA)...
  45. Decoster L, Vanacker L, Kenis C, Prenen H, Van Cutsem E, Van Der Auwera J, et al. Relevance of Geriatric Assessment in Older Patients With Colorectal Cancer. Clin Colorectal Cancer. 2017;16:e221-e229 pubmed publisher
    ..At follow-up (n = 164), functional decline was observed in 29 patients (18%) for activities of daily living (ADL) and in 60 patients (37%) for instrumental activities of daily living (IADL)...
  46. Johnson C, McLeod K. Relationship between Fear of Falling and Preceived Difficulty with Grocery Shopping. J Frailty Aging. 2017;6:33-36 pubmed publisher
    Fear of falling is associated with self-imposed restrictions of basic and instrumental activities of daily living (ADL/IADL), leading greater risk for functional decline and falls...
  47. Hall A, Backonja U, Painter I, Cakmak M, Sung M, Lau T, et al. Acceptance and perceived usefulness of robots to assist with activities of daily living and healthcare tasks. Assist Technol. 2017;: pubmed publisher
    ..living with chronic conditions continues to rise, they will require assistance with activities of daily living (ADL) and healthcare tasks to continue living independently in their homes...
  48. Cohen Mansfield J. Predictors of Smoking Cessation in Old-Old Age. Nicotine Tob Res. 2016;18:1675-9 pubmed publisher
    ..By means of interviews, we assessed smoking, health, Activities of Daily Living (ADL), Instrumental ADL, cognitive dysfunction, and well-being. Continuing smokers tended to be lonelier...
  49. Oldenkamp M, Hagedoorn M, Slaets J, Stolk R, Wittek R, Smidt N. Subjective burden among spousal and adult-child informal caregivers of older adults: results from a longitudinal cohort study. BMC Geriatr. 2016;16:208 pubmed
    ..including multimorbidity, functional limitations (Katz Index of Independence Basic Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL), and cognitive functioning problems (EQ-5D + C)...
  50. Perna S, Francis M, Bologna C, Moncaglieri F, Riva A, Morazzoni P, et al. Performance of Edmonton Frail Scale on frailty assessment: its association with multi-dimensional geriatric conditions assessed with specific screening tools. BMC Geriatr. 2017;17:2 pubmed publisher
    ..evaluated with the number of diseases), functional independence (Barthel Index and Activities Daily Living; BI, ADL, IADL), use of drugs (counting of drugs taken every day), Mini Nutritional Assessment (MNA), Geriatric Depression ..
  51. Pasteuning Vuhman S, Putker K, Tanganyika de Winter C, Boertje van der Meulen J, Van Vliet L, Overzier M, et al. Natural disease history of mouse models for limb girdle muscular dystrophy types 2D and 2F. PLoS ONE. 2017;12:e0182704 pubmed publisher
    ..Implementing the TREAD-NMD standardized operating procedures, we here subjected LGMD2D (SGCA-null), LGMD2F (SGCD-null) and wild type (C57BL/6J) mice to five functional tests from the age of 4 to 32 ..
  52. Bandelow S, Xu X, Xiao S, Hogervorst E. Cluster Analysis of Physical and Cognitive Ageing Patterns in Older People from Shanghai. Diagnostics (Basel). 2016;6: pubmed publisher
    ..cognitive and physical function in older age, and their respective impacts on activities of daily living (ADL)...
  53. Kurichi J, Kwong P, Xie D, Bogner H. Predictive Indices for Functional Improvement and Deterioration, Institutionalization, and Death Among Elderly Medicare Beneficiaries. PM R. 2017;9:1065-1076 pubmed publisher
    ..The outcome was activity of daily living (ADL) stage transitions over 2 years following entry into the MCBS...
  54. Nyrop K, Callahan L, Cleveland R, Arbeeva L, Hackney B, Muss H. Randomized Controlled Trial of a Home-Based Walking Program to Reduce Moderate to Severe Aromatase Inhibitor-Associated Arthralgia in Breast Cancer Survivors. Oncologist. 2017;22:1238-1249 pubmed publisher
    ..increased walking minutes per week, reduced stiffness, less difficulty with activities of daily living (ADL), and less perceived helplessness in managing joint symptoms...
  55. Liebl M, Elmer N, Schwedtke C, Schröder I, Reishauer A. [Interdisciplinary Acute Medical Rehabilitation after Sepsis - A Retrospective Analysis]. Rehabilitation (Stuttg). 2017;: pubmed publisher
    ..Its aim is to improve the patients' functioning in mobility and activities of daily living (ADL) to enable further post-acute rehabilitation interventions...
  56. Giannasi S, Venuti M, Midley A, Roux N, Kecskes C, San Roman E. Mortality risk factors in elderly patients in intensive care without limitation of therapeutic effort. Med Intensiva. 2018;42:482-489 pubmed publisher
    ..status were recorded: nutritional status (subjective global assessment), functionality (activities of daily living [ADL] and Barthel index), cognitive abilities (Short Reporting Questionnaire on Cognitive Decline in the Elderly [..
  57. Kalmet P, Meys G, V Horn Y, Evers S, Seelen H, Hustinx P, et al. Permissive weight bearing in trauma patients with fracture of the lower extremities: prospective multicenter comparative cohort study. BMC Surg. 2018;18:8 pubmed publisher
    ..The duration of follow up is 6 months, with measurements taken at baseline, 2,6,12 and 26 weeks post-surgery. ADL with Lower Extremity Functional Scale...
  58. Chekani F, Bali V, Aparasu R. Quality of life of patients with Parkinson's disease and neurodegenerative dementia: A nationally representative study. Res Social Adm Pharm. 2016;12:604-13 pubmed publisher
    ..was captured based on Physical Component Summary (PCS), Mental Component Summary (MCS), Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL)...
  59. Tramontano A, Veronese N, Giantin V, Manzato E, Rodríguez Hurtado D, Trevisan C, et al. Nutritional status, physical performance and disability in the elderly of the Peruvian Andes. Aging Clin Exp Res. 2016;28:1195-1201 pubmed
    ..by assessing participants' self-reported difficulty in performing one or more basic activities of daily living (ADL), and instrumental activities of daily living (IADL). The prevalence of malnutrition was 9...
  60. Alcalá J, Ureña J, Hernandez A, Gualda D. Assessing Human Activity in Elderly People Using Non-Intrusive Load Monitoring. Sensors (Basel). 2017;17: pubmed publisher
    ..b>ADL monitoring systems use many heterogeneous sensors, are less intrusive, and are less expensive than BSN, however, ..
  61. Kantanen A, Kälviäinen R, Parviainen I, Ala Peijari M, Bäcklund T, Koskenkari J, et al. Predictors of hospital and one-year mortality in intensive care patients with refractory status epilepticus: a population-based study. Crit Care. 2017;21:71 pubmed publisher
    ..215, 95% CI 1.20-3.84, p = 0.010) and dependence in activities of daily living (ADL) (aOR 2.553, 95% CI 1.537-4.243, p < 0.0001)...
  62. Smagula S, Beach S, Rosso A, Newman A, Schulz R. Brain Structural Markers and Caregiving Characteristics as Interacting Correlates of Caregiving Strain. Am J Geriatr Psychiatry. 2017;25:582-591 pubmed publisher
    ..adjustments for: care recipient's memory and behavioral problems, caregiver's depression symptoms, and caregiver's ADL impairment...
  63. Prestmo A, Saltvedt I, Helbostad J, Taraldsen K, Thingstad P, Lydersen S, et al. Who benefits from orthogeriatric treatment? Results from the Trondheim hip-fracture trial. BMC Geriatr. 2016;16:49 pubmed publisher
    ..were age (over/under 80 years), gender, fracture type (intra-/extracapsular), and pre-fracture instrumental ADL (i-ADL) (defined as over/under 45 on the Nottingham Extended ADL scale)...
  64. Fond G, Fajula C, Dassa D, Brunel L, Lançon C, Boyer L. Potentially inappropriate psychotropic prescription at discharge is associated with lower functioning in the elderly psychiatric inpatients. A cross-sectional study. Psychopharmacology (Berl). 2016;233:2549-58 pubmed publisher
    ..Daily functioning was evaluated by the daily living (ADL) scale...
  65. Jacob M, Yee L, Diehr P, Arnold A, Thielke S, Chaves P, et al. Can a Healthy Lifestyle Compress the Disabled Period in Older Adults?. J Am Geriatr Soc. 2016;64:1952-1961 pubmed publisher
    ..Years of life (YoL) was defined as years until death. Years of able life (YAL) was defined as years without any ADL difficulty...
  66. Jung H, Sim G, Bae K, Kekatpure A, Chun J, Jeon I. Rotator cuff surgery in patients older than 75 years with large and massive tears. J Shoulder Elbow Surg. 2017;26:265-272 pubmed publisher
    ..The Katz index of activity of daily living (ADL) and functional independence measure motor score were used to evaluate ADLs...
  67. Nwachukwu B, Fields K, Chang B, Nawabi D, Kelly B, Ranawat A. Preoperative Outcome Scores Are Predictive of Achieving the Minimal Clinically Important Difference After Arthroscopic Treatment of Femoroacetabular Impingement. Am J Sports Med. 2017;45:612-619 pubmed publisher
    ..5 ± 10.3 years), and 57.1% were female. The MCID for the mHHS, HOS-Activities of Daily Living (HOS-ADL), HOS-Sports, and iHOT-33 was 8.2, 8.3, 14.5, and 12.1, respectively...
  68. Sanders A, Jain D, Sofer T, Kerr K, Laurie C, Shaffer J, et al. GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos. J Dent Res. 2017;96:277-284 pubmed publisher
    ..A locus near the sarcoglycan alpha ( SGCA), rs4794106, was suggestive in the discovery analysis ( P = 2.6 × 106) and replicated (i.e...
  69. Zhou Y, Kang Y, Chen C, Xu F, Wang H, Jin R. Combination of TNM staging and pathway based risk score models in patients with gastric cancer. J Cell Biochem. 2017;: pubmed publisher
    ..A five-gene signature comprising FARP1, SGCE, SGCA, LAMA4 and COL9A2 was strongly associated with recurrence of patients with curative surgery plus chemoradiotherapy ..
  70. Spencer Gardner L, Bedi A, Stuart M, Larson C, Kelly B, Krych A. Ischiofemoral impingement and hamstring dysfunction as a potential pain generator after ischial tuberosity apophyseal fracture non-union/malunion. Knee Surg Sports Traumatol Arthrosc. 2017;25:55-61 pubmed publisher
    ..At a mean of 2.2-year follow-up (range 1.7-3.5), the median post-operative mHHS was 89.7 (65.7-96.8) and HOS ADL and Sport subscales were 90 % or greater in all cases...
  71. Garrison B, Wade E. Relative accuracy of time and frequency domain features to quantify upper extremity coordination. Conf Proc IEEE Eng Med Biol Soc. 2015;2015:4958-61 pubmed publisher
    ..of inertial sensors to capture measures of limb coordination in non-disabled individuals during the performance of ADL inspired tasks...
  72. Tardy N, Thaunat M, Sonnery Cottet B, Murphy C, Chambat P, Fayard J. Extension deficit after ACL reconstruction: Is open posterior release a safe and efficient procedure?. Knee. 2016;23:465-71 pubmed publisher
    ..8±5 (SD); symptoms 88±8.6 (SD); ADL 96.8±3.7 (SD); sports activities 83.6±12.3 (SD); and quality of life 82.9±8.8 (SD)...
  73. Yu Y, Zhi L, Guan X, Wang D, Wang D. FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans. Sci Rep. 2016;6:21485 pubmed publisher
    ..Using assay system of preference choice on bacterial foods, OP50 and PA14, we identified the involvement of ADL sensory neurons in the control of preference choice in Caenorhabditis elegans...
  74. Berggren M, Stenvall M, Englund U, Olofsson B, Gustafson Y. Co-morbidities, complications and causes of death among people with femoral neck fracture - a three-year follow-up study. BMC Geriatr. 2016;16:120 pubmed publisher
    ..Medical records and death certificates were analysed. Multivariate analysis revealed that cancer, dependence in P-ADL (Personal Activities of Daily Living), cardiovascular disease, dementia at baseline or pulmonary emboli or cardiac ..
  75. Solé Auró A, Alcañiz M. Educational attainment, gender and health inequalities among older adults in Catalonia (Spain). Int J Equity Health. 2016;15:126 pubmed publisher
    ..health inequalities: self-perceived health, functional limitations, and restrictions on activities of daily living (ADL)...
  76. Kotagal V, Lineback C, Bohnen N, Albin R. Orthostatic hypotension predicts motor decline in early Parkinson disease. Parkinsonism Relat Disord. 2016;32:127-129 pubmed publisher
    ..40, p = 0.017) at week 102 but not with UPDRS ADL score (t = 0.83, p = 0.409)...
  77. Woods S, Weinborn M, Velnoweth A, Rooney A, Bucks R. Memory for intentions is uniquely associated with instrumental activities of daily living in healthy older adults. J Int Neuropsychol Soc. 2012;18:134-8 pubmed publisher
    ..the MIST event-based PM score and PRMQ PM scale were significantly associated with the total number of instrumental ADL (IADL) domains in which participants reported needing assistance...
  78. Best D, Osterkamp E, Demmel K, Kiniyalocts S, Mock S, Mulligan K, et al. Increasing Activities of Daily Living Is as Easy as 1-2-3. J Pediatr Oncol Nurs. 2016;33:345-52 pubmed publisher
    Human flora are the most common cause of bacteremia in immunocompromised patients. Activities of daily living (ADL), including oral care and daily chlorhexidine gluconate bathing, can lower the risk of infection...
  79. Wattmo C, Minthon L, Wallin Ã. Mild versus moderate stages of Alzheimer's disease: three-year outcomes in a routine clinical setting of cholinesterase inhibitor therapy. Alzheimers Res Ther. 2016;8:7 pubmed publisher
    ..6 months, patients were assessed using cognitive, global, instrumental and basic activities of daily living (ADL) scales. Potential predictors of deterioration in moderate AD were analysed using mixed-effects models...
  80. Chao W, Chuang P, Wu D, Wu C, Liu P, Shieh C, et al. Using genotyping to delineate tuberculosis transmission in long-term care facilities: single facility 4-year experience. BMC Infect Dis. 2017;17:421 pubmed publisher
    ..and body mass index, subjects with clustered TB infection were less likely to be Activities of Daily Living (ADL)-dependence (adjOR 0.073, 95% CI 0.007-0.758) when compared with subjects having individual TB infections...
  81. Hanada M, Sakamoto N, Ishimatsu Y, Kakugawa T, Obase Y, Kozu R, et al. Effect of long-term treatment with corticosteroids on skeletal muscle strength, functional exercise capacity and health status in patients with interstitial lung disease. Respirology. 2016;21:1088-93 pubmed publisher
    ..chronic corticosteroid administration on skeletal muscle strength, exercise capacity, activities of daily living (ADL) and health status in ILD patients...
  82. Duggan D, Gorospe J, Fanin M, Hoffman E, Angelini C. Mutations in the sarcoglycan genes in patients with myopathy. N Engl J Med. 1997;336:618-24 pubmed
    ..Defects in the genes coding for the sarcoglycan proteins are limited to patients with Duchenne-like and limb-girdle muscular dystrophy with normal dystrophin and occur in 11 percent of such patients. ..
  83. Mendell J, Rodino Klapac L, Rosales X, Coley B, Galloway G, Lewis S, et al. Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D. Ann Neurol. 2010;68:629-38 pubmed publisher
    ..study was to attain long-lasting alpha-sarcoglycan gene expression in limb-girdle muscular dystrophy, type 2D (LGMD2D) subjects mediated by adeno-associated virus (AAV) gene transfer under control of a muscle specific promoter (tMCK)..
  84. Babameto Laku A, Tabaku M, Tashko V, Cikuli M, Mokini V. The first case of primary alpha-sarcoglycanopathy identified in Albania, in two siblings with homozygous alpha-sarcoglycan mutation. Genet Couns. 2011;22:377-83 pubmed
    Limb-girdle muscular dystrophy type 2D (LGMD2D) is caused by autosomal recessive mutations in the alpha-sarcoglycan gene...
  85. Mechlenburg I, Nyengaard J, Gelineck J, de Raedt S, Søballe K. Cyst volume in the acetabulum and femoral head decreases after periacetabular osteotomy. Hip Int. 2012;22:313-8 pubmed publisher
    ..73 cm³. The mean subscore for Pain was 75, Symptoms 75, ADL 83, Sport/recreation 63 and Quality Of Life 62...
  86. Bianchini E, Fanin M, Mamchaoui K, Betto R, Sandonà D. Unveiling the degradative route of the V247M ?-sarcoglycan mutant responsible for LGMD-2D. Hum Mol Genet. 2014;23:3746-58 pubmed publisher
    ..This represents the first evidence that the activity of E3 ligases, the enzymes in charge of mutant fate, can be eligible for drug interventions to treat sarcoglycanopathy. ..
  87. Lami D, Chivot M, Caubère A, Galland A, Argenson J. First-line management of distal humerus fracture by total elbow arthroplasty in geriatric traumatology: Results in a 21-patient series at a minimum 2years' follow-up. Orthop Traumatol Surg Res. 2017;103:891-897 pubmed publisher
    ..Mean follow-up was 3.2years, with functional (Quick DASH and MEPS), cognitive (MMSE), autonomy-related (ADL) and radiological assessment (Morrey). Mean MEPS was 84 and QuickDASH 32.4...
  88. Nakamura T, Michikawa T, Imamura H, Takebayashi T, Nishiwaki Y. Relationship Between Depressive Symptoms and Activity of Daily Living Dependence in Older Japanese: The Kurabuchi Study. J Am Geriatr Soc. 2017;65:2639-2645 pubmed publisher
    ..The objective of the study was to examine the association between depressive symptoms and future ADL dependence and to investigate how this association varies according to living circumstances and marital status.
  89. Gulart A, Munari A, Tressoldi C, dos Santos K, Karloh M, Mayer A. Glittre-ADL Multiple Tasks Induce Similar Dynamic Hyperinflation With Different Metabolic and Ventilatory Demands in Patients With COPD. J Cardiopulm Rehabil Prev. 2017;37:450-453 pubmed publisher
    This cross-sectional study compared the physiological responses and dynamic hyperinflation (DH) of the Glittre-ADL test (TGlittre) and its specific tasks in patients with chronic obstructive pulmonary disease (COPD).
  90. Dutil E, Bottari C, Auger C. Test-Retest Reliability of a Measure of Independence in Everyday Activities: The ADL Profile. Occup Ther Int. 2017;2017:3014579 pubmed publisher
    ..Very few performance-based measures used in occupational therapy have established test-retest reliability coefficients...
  91. Yan C, Song J, Pang S, Yi F, Xi J, Zhou L, et al. Palpebral portion of the orbicularis oculi muscle to repetitive nerve stimulation testing: A potential assessment indicator in patients with generalized myasthenia gravis. J Clin Neurosci. 2018;48:238-242 pubmed publisher
    ..scores, MG-specific manual muscle testing (MMT) scores and myasthenia gravis-related activities of daily living (MG-ADL) scores...
  92. White S, Uitte de Willige S, Verbove D, Politano L, Ginjaar I, Breuning M, et al. Sarcoglycanopathies and the risk of undetected deletion alleles in diagnosis. Hum Mutat. 2005;26:59 pubmed
    We have designed Multiplex Amplifiable Probe Hybridization (MAPH) probes for 28 exons of the sarcoglycan genes SGCA, SGCB, SGCG, and SGCD...