Gene Symbol: SEPT4
Description: septin 4
Alias: ARTS, BRADEION, CE5B3, MART, PNUTL2, SEP4, hCDCREL-2, hucep-7, septin-4, CE5B3 beta, apoptosis-related protein in the TGF-beta signaling pathway, bradeion beta, brain protein H5, cell division control-related protein 2, cerebral protein 7, peanut-like protein 2, septin-M
Species: human
Products:     SEPT4

Top Publications

  1. Garcia W, Rodrigues N, de Oliveira Neto M, de Araújo A, Polikarpov I, Tanaka M, et al. The stability and aggregation properties of the GTPase domain from human SEPT4. Biochim Biophys Acta. 2008;1784:1720-7 pubmed publisher
    ..Human SEPT4 is a member of this family and its tissue-specific ectopic expression profile in colorectal and urologic cancer ..
  2. Martinez C, Sanjuan M, Dent J, Karlsson L, Ware J. Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol. Biochem J. 2004;382:783-91 pubmed
    ..expressed in platelets and neurons, SEPT4 [previously designated H5, CDCrel-2 (cell-division-control-related-2), PNUTL2], SEPT5 (CDCrel-1, PNUTL1) and SEPT8 (KIAA0202)...
  3. Lhuillier P, Rode B, Escalier D, Lores P, Dirami T, Bienvenu T, et al. Absence of annulus in human asthenozoospermia: case report. Hum Reprod. 2009;24:1296-303 pubmed publisher
    ..In the mouse, deletion of Septin 4, a structural component of the sperm annulus, prevents annulus formation and leads to MP-PP disjunction, ..
  4. Popovic M, Chan C, Lattanzio N, El Defrawy S, Schlenker M. Comparative cost evaluation of brand name and generic ophthalmology medications in Ontario. Can J Ophthalmol. 2018;53:173-187 pubmed publisher
    ..which includes the cost of the medication, mark-up, and dispensing cost, was provided by Ontario Shoppers Drug Mart stores in July 2016 for 103 common medications using typical dosages and durations...
  5. da Silva T, Costa C, Galvão A, Bomfim L, Rodrigues A, Mota M, et al. Cytotoxic potential of selected medicinal plants in northeast Brazil. BMC Complement Altern Med. 2016;16:199 pubmed publisher
    ..Cucurbitaceae), Ocotea glomerata (Nees) Mez (Lauraceae), Ocotea longifolia Kunth (Oreodaphne opifera Mart. Nees) (Lauraceae), Pavonia fruticosa (Mill.) Fawc. & Rendle (Malvaceae), Psychotria capitata Ruiz & Pav...
  6. Basu R, May Wu X, Malig B, Broadwin R, Gold E, Qi L, et al. Estimating the associations of apparent temperature and inflammatory, hemostatic, and lipid markers in a cohort of midlife women. Environ Res. 2017;152:322-327 pubmed publisher
    ..ozone, carbon monoxide, and nitrogen dioxide from the US Environmental Protection Agency Air Quality Data Mart were considered as confounders. All analyses were stratified by warm and cold seasons. More significant (p < 0...
  7. Faria E Souza B, Carvalho H, Taglialegna T, Barros A, da Cunha E, Ferreira I, et al. Effect of Euterpe oleracea Mart. (Açaí) Oil on Dyslipidemia Caused by Cocos nucifera L. Saturated Fat in Wistar Rats. J Med Food. 2017;20:830-837 pubmed publisher
    ..The results obtained suggest that OFEO has an antiatherogenic effect in a rat model of dyslipidemia. ..
  8. El Morsy E, Ahmed M, Ahmed A. Attenuation of renal ischemia/reperfusion injury by açaí extract preconditioning in a rat model. Life Sci. 2015;123:35-42 pubmed publisher
    ..On the other hand, açaí (Euterpe oleracea Mart. Palmae, Arecaceae) has recently gained considerable appreciation as a natural source of antioxidants...
  9. Yamaguchi Y, Hearing V. Physiological factors that regulate skin pigmentation. Biofactors. 2009;35:193-9 pubmed publisher
    ..whose sorting involves adaptor protein 1A (AP1A), AP1B, AP2, and spectrin, as well as a chaperone-like component, MART-1. During their maturation, melanosomes move from the perinuclear area toward the plasma membrane...

More Information

Publications152 found, 100 shown here

  1. Koka P. Biomarker discovery and biotherapeutics applications of photosynthetic light-harvesting and bioluminescence light-emitting chromophore-protein complexes in stem cell biology and regenerative medicine. J Stem Cells. 2014;9:127-33 pubmed publisher
    ..gag-p24), non-communicable but also potential hereditary and malignant disorders (Cancer/Tumor Markers - Melan-A/Mart-1 of melanoma), normal immune response cells (Human/Mouse/species cellular MHC/TCR/CD45/CD33/CD56/CD19/CD41), and ..
  2. de Oliveira H, de Castro G, Correa L, Silvestre W, do Nascimento S, da Silva Valadares R, et al. Coupling physiological analysis with proteomic profile to understand the photosynthetic responses of young Euterpe oleracea palms to drought. Photosynth Res. 2018;: pubmed publisher
    This study examined whether drought sensitivity in açaí (Euterpe oleracea Mart.) is associated with reductions in photosynthesis and increasing oxidative stress in response to down-regulation of proteins related to photosynthetic ..
  3. Zhang Y, Rants o T, Jung D, López E, Abbott K, Pondugula S, et al. Screening for CYP3A4 inhibition and induction coupled to parallel artificial membrane permeability assay (PAMPA) for prediction of botanical-drug interactions: The case of açaí and maca. Phytomedicine. 2019;59:152915 pubmed publisher
    ..the potential for botanical-drug interactions of Lepidium meyenii Walpers (maca) root and Euterpe oleracea Mart. (açaí) berries, two commonly used BDS, when co-administered with CYP3A4-metabolized drugs...
  4. Ma Y, Li M, Xu X, Fu Y, Xiong Z, Zhang L, et al. High-levels of resistance to quinolone and cephalosporin antibiotics in MDR-ACSSuT Salmonella enterica serovar Enteritidis mainly isolated from patients and foods in Shanghai, China. Int J Food Microbiol. 2018;286:190-196 pubmed publisher
    ..27%) followed by blaTEM (23.6%) and blaOXY (4.55%). Mart, prot6E, steB, fimA, and sopE2 genes (100%) were the most in these isolates...
  5. Pala D, Barbosa P, Silva C, de Souza M, Freitas F, Volp A, et al. Açai (Euterpe oleracea Mart.) dietary intake affects plasma lipids, apolipoproteins, cholesteryl ester transfer to high-density lipoprotein and redox metabolism: A prospective study in women. Clin Nutr. 2018;37:618-623 pubmed publisher
  6. Colhoun H, Rubio Gozalbo E, Bosch A, Knerr I, Dawson C, Brady J, et al. Fertility in classical galactosaemia, a study of N-glycan, hormonal and inflammatory gene interactions. Orphanet J Rare Dis. 2018;13:164 pubmed publisher
    ..01) as was the inflammatory genes ANXA1 and ICAM1 and the apoptosis gene SEPT4 (p < 0.01)...
  7. Oyama L, Silva F, Carnier J, de Miranda D, Santamarina A, Ribeiro E, et al. Juçara pulp supplementation improves glucose tolerance in mice. Diabetol Metab Syndr. 2016;8:8 pubmed publisher
    ..factor to promote obesity and the consumption of food with antioxidant properties, like Juçara (Euterpe edulis Mart), could be a tool to prevent the deleterious effect of high white adipose deposition...
  8. Ford C, Kim M, Dancy B. Perceptions of hypertension and contributing personal and environmental factors among rural Southern African American women. Ethn Dis. 2009;19:407-13 pubmed
    ..Blood pressure monitors were available in their homes, at grocery stores and at Wal-Mart. No church health programs were available, but some churches had nurses on duty who offered blood pressure and ..
  9. Fustinoni Reis A, Arruda S, Dourado L, da Cunha M, Siqueira E. Tucum-Do-Cerrado (Bactris setosa Mart.) Consumption Modulates Iron Homeostasis and Prevents Iron-Induced Oxidative Stress in the Rat Liver. Nutrients. 2016;8:38 pubmed publisher
    ..These results suggest that tucum-do-cerrado protects tissues against oxidative damage, by reducing iron availability in liver and consequently inhibiting liver Hamp expression. ..
  10. Le Moignic A, Malard V, Benvegnu T, Lemiègre L, Berchel M, Jaffres P, et al. Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells. J Control Release. 2018;278:110-121 pubmed publisher three therapeutic pre-clinical murine tumor models such as E7-expressing TC1 cells, OVA-expressing EG7 cells and MART-1-expressing B16F0 cells, triMN-LPR carrying mRNA encoding the respective antigens significantly exert curative ..
  11. de Oliveira P, da Costa C, de Bem G, Cordeiro V, Santos I, de Carvalho L, et al. Euterpe oleracea Mart.-Derived Polyphenols Protect Mice from Diet-Induced Obesity and Fatty Liver by Regulating Hepatic Lipogenesis and Cholesterol Excretion. PLoS ONE. 2015;10:e0143721 pubmed publisher
  12. Stonis J, Remeikis A, Diskus A, Megoran N. New species of leaf-mining Nepticulidae (Lepidoptera) from the Neotropical and Ando-Patagonian regions, with new data on host plants. Zootaxa. 2017;4272:1-39 pubmed publisher
    ..f.), Fabaceae (Inga spectabilis (Vahl) Willd. or I. edulis Mart.), Rhamnaceae (Colletia spinosissima J. F. Gmel.), Geraniaceae or Vivianiaceae (Rhynchotheca spinosa Ruiz & Pav...
  13. Santamarina A, Jamar G, Mennitti L, de Rosso V, Cesar H, Oyama L, et al. The Use of Juçara (Euterpe edulis Mart.) Supplementation for Suppression of NF-κB Pathway in the Hypothalamus after High-Fat Diet in Wistar Rats. Molecules. 2018;23: pubmed publisher
    ..25% group. In summary, the HFJ 0.25% group had better protective effects than those in the HFJ 0.5%. Therefore, 0.25% juçara can be used to protect against central inflammation through the high-fat diet-induced NF-κB pathway. ..
  14. Tirloni C, Palozi R, Tomazetto T, Vasconcelos P, Souza R, Dos Santos A, et al. Ethnopharmacological approaches to kidney disease-prospecting an indigenous species from Brazilian Pantanal. J Ethnopharmacol. 2018;211:47-57 pubmed publisher
    Although Luehea divaricata Mart. (Malvaceae) is popularly used by the population of the Brazilian Pantanal for the treatment of different types of kidney diseases, no study has been carried out to prove this ethnobotanical indication...
  15. O Brien S, Koch T, Vesely S, Schwarz E. Hormonal Contraception and Risk of Thromboembolism in Women With Diabetes. Diabetes Care. 2017;40:233-238 pubmed publisher
    ..We used data from 2002-2011 in Clinformatics Data Mart to identify women in the U.S...
  16. Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed publisher
    ..melanoma cell lines were CD271(+) and deficient for expression of melanocyte differentiation antigens (MDAs) MART-1, gp100, tyrosinase and of GPNMB, PGC1-α and Rab27a, all regulated by MITF...
  17. da Silva A, Oliveira G, Medeiros S, Sousa A, Lopes L, David J, et al. Pre-clinical toxicology of garcinielliptone FC, a tautomeric pair of polyprenylated benzophenone, isolated from Platonia insignis Mart seeds. Phytomedicine. 2016;23:477-82 pubmed publisher
    ..The acute toxicity study indicated that GFC treatment, at selected doses given orally and intraperitoneally, showed relatively low risk of toxicity in all test animals, suggesting that it is safe for further investigation. ..
  18. Qiao J, Zhang Q, Alali W, Wang J, Meng L, Xiao Y, et al. Characterization of extended-spectrum ?-lactamases (ESBLs)-producing Salmonella in retail raw chicken carcasses. Int J Food Microbiol. 2017;248:72-81 pubmed publisher
    ..1% harbored spvR (lowest) and 90.6% harbored marT and steB (highest). All isolates carried at least one virulence gene, 83.3% of the isolates co-carried ?10, 17...
  19. Santamarina A, Jamar G, Mennitti L, de Cassia Cesar H, de Rosso V, Vasconcelos J, et al. Supplementation of Juçara Berry (Euterpe edulis Mart.) Modulates Epigenetic Markers in Monocytes from Obese Adults: A Double-Blind Randomized Trial. Nutrients. 2018;10: pubmed publisher
    ..Concluding, juçara supplementation improved the serum fatty acids profile, modulating the epigenetic markers in monocytes from obese individuals. ..
  20. Wilgenhof S, Corthals J, Van Nuffel A, Benteyn D, Heirman C, Bonehill A, et al. Long-term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases. Cancer Immunol Immunother. 2015;64:381-8 pubmed publisher
    ..accomplished by co-electroporation of mRNA encoding a fusion protein between MAGE-A1, -A3, -C2, Tyrosinase, MelanA/MART-1, or gp100, and an HLA class II-targeting sequence. DCs were administered by 4-6 bi-weekly intradermal injections...
  21. Petruk G, Illiano A, Del Giudice R, Raiola A, Amoresano A, Rigano M, et al. Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts. J Photochem Photobiol B. 2017;172:42-51 pubmed publisher
  22. Arneja S, Gujar N. Renal cell carcinoma with t(6:11) (p21;q12). A case report highlighting distinctive immunohistologic features of this rare tumor. Int J Surg Case Rep. 2015;7C:16-9 pubmed publisher
    ..HMB 45 (human melanoma black 45) and Melan- A /MART 1 (melanoma antigen recognized by T cells) were moderate to strongly expressed...
  23. Magrini F, Specht A, Gaio J, Girelli C, Migues I, Heinzen H, et al. Viability of Cabralea canjerana extracts to control the South American fruit fly, Anastrepha fraterculus. J Insect Sci. 2014;14:47 pubmed publisher
    ..the activity of ethyl acetate and ethanol extracts from the fruit and seeds of Cabralea canjerana (Vellozo) Mart (Sapindales: Meliaceae) on Anastrepha fraterculus (Wiedemann) (Diptera: Tephritidae)...
  24. Yenerel M, Kalayoglu Besisik S, Perdeci O, Gurses N, Tunc M, Sargin D. Hyperbaric Oxygen: an important treatment modality in severe hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Turk J Haematol. 2009;26:176-80 pubmed
    ..YÖNTEMLER: Mart 1993 ve A?ustos 2006 y?llar? aras?nda 161 hastaya allojeneik hematopoetik kök hücre nakli uyguland?...
  25. Serter S, Ceylan C, Tuncyurek O, Orguc S, Pabuçcu Y. Sonographic evaluation of spleen size and prevalence of accessory spleen in a healthy male Turkish population. Turk J Haematol. 2010;27:25-8 pubmed
    ..YÖNTEMLER: Mart 1993 ve A?ustos 2006 y?llar? aras?nda 161 hastaya allojeneik hematopoetik kök hücre nakli uyguland?...
  26. Brito C, Stavroullakis A, Oliveira T, Prakki A. Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss. Arch Oral Biol. 2017;83:348-356 pubmed publisher
    ..investigate cytotoxicity and HIF-1α expression through the NF-κB pathway by polyphenol velutin (Euterpe oleracea Mart.), found in the pulp of acai fruit, during inflammatory RAW 264.7 differentiation. RAW 264...
  27. Tkacz J, Ellis L, Meyer R, Bolge S, Brady B, Ruetsch C. Quality process measures for rheumatoid arthritis: performance from members enrolled in a national health plan. J Manag Care Spec Pharm. 2015;21:135-43 pubmed
    ..x) during calendar years 2008 through 2012 were extracted from the Optum Clinformatics Data Mart database...
  28. Jeon T, Yang H, Lee C, Oh S, Seo D, Baik I, et al. Electro-hyperthermia up-regulates tumour suppressor Septin 4 to induce apoptotic cell death in hepatocellular carcinoma. Int J Hyperthermia. 2016;32:648-56 pubmed publisher
    ..The growth inhibitory effects are induced through a subset of molecular changes. Notably the expression level of septin 4 (SEPT4) (involved in pro-apoptotic activity and growth suppression) was up-regulated, whereas a key regulator of ..
  29. Pedrosa T, Barros A, Nogueira J, Fruet A, Rodrigues I, Calcagno D, et al. Anti-wrinkle and anti-whitening effects of jucá (Libidibia ferrea Mart.) extracts. Arch Dermatol Res. 2016;308:643-654 pubmed
    ..LFB and LFP decreased the melanin content in B16F10 due to tyrosinase inhibitory activity. L. ferrea extracts has high potential as a cosmetic ingredient due to its anti-wrinkle and depigmentant effects. ..
  30. Chandrasekaran M, Chandrasekar R, Chun S, Sathiyabama M. Isolation, characterization and molecular three-dimensional structural predictions of metalloprotease from a phytopathogenic fungus, Alternaria solani (Ell. and Mart.) Sor. J Biosci Bioeng. 2016;122:131-9 pubmed publisher
    ..Thus, it can be concluded that the major proteinases of AsK are divalent cation-requiring metalloproteinases and make them potential targets of protease inhibitors designing. ..
  31. Najjar Y, Ding F, Lin Y, VanderWeele R, Butterfield L, Tarhini A. Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab. J Transl Med. 2017;15:39 pubmed publisher
    ..into 5 groups and stimulated with controls or shared melanoma antigen overlapping peptide pools (NY-ESO 1, gp-100, MART-1). Secreted cytokines, chemokines and growth factors were assessed using Luminex...
  32. Chapman K, Hinds D, Piazza P, Raherison C, Gibbs M, Greulich T, et al. Physician perspectives on the burden and management of asthma in six countries: The Global Asthma Physician Survey (GAPS). BMC Pulm Med. 2017;17:153 pubmed publisher
    ..Awareness of single maintenance and reliever therapy (SMART/MART) varied among countries (56-100%); although most physicians (72%) had prescribed SMART/MART, the majority (91%) co-..
  33. Ayi Q, Zeng B, Liu J, Li S, van Bodegom P, Cornelissen J. Oxygen absorption by adventitious roots promotes the survival of completely submerged terrestrial plants. Ann Bot. 2016;: pubmed
    ..TakingAlternanthera philoxeroides(Mart.) Griseb...
  34. Houel E, Nardella F, Jullian V, Valentin A, Vonthron Sénécheau C, Villa P, et al. Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians. J Ethnopharmacol. 2016;187:241-8 pubmed publisher
    Psidium acutangulum Mart. ex DC is a small tree used by the Wayana Amerindians from the Upper-Maroni in French Guiana for the treatment of malaria...
  35. Oliveira C, Veloso C, Ferreira R, Lage G, Pimenta L, Duarte I, et al. Peltatoside Isolated from Annona crassiflora Induces Peripheral Antinociception by Activation of the Cannabinoid System. Planta Med. 2017;83:261-267 pubmed publisher
    Peltatoside is a natural compound isolated from leaves of Annona crassiflora Mart., a plant widely used in folk medicine...
  36. Madorsky Rowdo F, Barón A, von Euw E, Mordoh J. In vitro long-term treatment with MAPK inhibitors induces melanoma cells with resistance plasticity to inhibitors while retaining sensitivity to CD8 T cells. Oncol Rep. 2017;37:1367-1378 pubmed publisher
    ..Notably, SUR cells were efficiently lysed by cytotoxic T lymphocytes recognizing MART-1 and gp100 melanoma differentiation antigens...
  37. Moraes L, Rohor B, Areal L, Pereira E, Santos A, Facundo V, et al. Medicinal plant Combretum leprosum mart ameliorates motor, biochemical and molecular alterations in a Parkinson's disease model induced by MPTP. J Ethnopharmacol. 2016;185:68-76 pubmed publisher
    ..leprosum ethanolic extract prevented motor and molecular changes induced by MPTP, and partially reverted dopamine deficit. Thus, our results demonstrate that C.l.EE has potential for the treatment and prevention of PD. ..
  38. Morais Braga M, Sales D, Carneiro J, Machado A, Dos Santos A, de Freitas M, et al. Psidium guajava L. and Psidium brownianum Mart ex DC.: Chemical composition and anti - Candida effect in association with fluconazole. Microb Pathog. 2016;95:200-207 pubmed publisher
    ..The aqueous and hydroethanolic extracts from Psidium brownianum Mart ex DC. and Psidium guajava L...
  39. Omür D, Oguzalp H, Kiraz H, Ekin S, Alan C, Ersay A, et al. The analgesic efficacy of ultrasound-guided transversus abdominis plane block on postoperative pain and morphine consumption in varicocelectomy. Saudi Med J. 2016;37:648-55 pubmed publisher
    ..This study was completed at the Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey, between January 2011 and April 2013...
  40. Duarte A, Lin Y, Sharma G. Incidence of right heart catheterization in patients initiated on pulmonary arterial hypertension therapies: A population-based study. J Heart Lung Transplant. 2017;36:220-226 pubmed publisher
    ..A retrospective review of administrative claims was performed using the Clinformatics Data Mart database. Individuals with an encounter diagnosis of pulmonary hypertension were identified by ICD-9 codes...
  41. Gilardoni G, Chiriboga X, Vita Finzi P, Vidari G. New 3,4-Secocycloartane and 3,4-Secodammarane Triterpenes from the Ecuadorian Plant Coussarea macrophylla. Chem Biodivers. 2015;12:946-54 pubmed publisher
    Coussarea macrophylla (Mart.) Müll.Arg. (Rubiaceae) was collected in Ecuador, and the bark was extracted with AcOEt...
  42. Kanduc D. Immunogenicity, Immunopathogenicity, and Immunotolerance in One Graph. Anticancer Agents Med Chem. 2015;15:1264-8 pubmed
    ..and immunotolerance, respectively, is graphically illustrated using a melanoma-associated antigen, Melan-A/Mart-1, as a model...
  43. Lacouth Silva F, Xavier C, da S Setúbal S, Pontes A, Nery N, de Castro O, et al. The effect of 3β, 6β, 16β-trihydroxylup-20(29)-ene lupane compound isolated from Combretum leprosum Mart. on peripheral blood mononuclear cells. BMC Complement Altern Med. 2015;15:420 pubmed publisher
    The Combretum leprosum Mart. plant, popularly known as mofumbo, is used in folk medicine for inflammation, pain and treatment of wounds...
  44. Oliveira T, Pereira A, Coppede J, França S, Ming L, Bertoni B. Genetic diversity analysis of Croton antisyphiliticus Mart. using AFLP molecular markers. Genet Mol Res. 2016;15: pubmed publisher
    Croton antisyphiliticus Mart. is a medicinal plant native to Cerrado vegetation in Brazil, and it is popularly used to treat urogenital tract infections...
  45. Simplicio R, Pereira D, Waldschmidt A. Transferability of microsatellite markers in Syagrus coronata (Mart.) Becc. (Arecaceae), an iconic palm tree from the Brazilian semiarid region. Genet Mol Res. 2017;16: pubmed publisher
    ..785 to 1.000. In conclusion, the tested loci are transferrable and highly efficient to population studies in S. coronata, thus minimizing the lack of species-specific loci to the genetic monitoring of licuri populations. ..
  46. Johnson A, Stone D, Celi L, Pollard T. The MIMIC Code Repository: enabling reproducibility in critical care research. J Am Med Inform Assoc. 2017;: pubmed publisher
    ..In this paper we outline the Medical Information Mart for Intensive Care (MIMIC) Code Repository, a centralized code base for generating reproducible studies on an ..
  47. Erasto P, Omolo J, Sunguruma R, Munissi J, Wiketye V, de Konig C, et al. Evaluation of Antimycobacterial Activity of Higenamine Using Galleria mellonella as an In Vivo Infection Model. Nat Prod Bioprospect. 2018;8:63-69 pubmed publisher
    The Phytochemical investigation on MeOH extract on the bark of Aristolochia brasiliensis Mart. & Zucc (Aristolochiaceae) led to the isolation of major compound (1) as light brown grainy crystals...
  48. Li Y, Feng X, Ji X, Wang Q, Gao X, Yang X, et al. [Expression of SEPT4 protein in the ejaculated sperm of idiopathic asthenozoospermic men]. Zhonghua Nan Ke Xue. 2011;17:699-702 pubmed
    To investigate the role of the SEPT4 protein in the pathogenesis of idiopathic asthenozoospermia...
  49. Costa E, Lopes S, Melo J. Floristic similarity and dispersal syndromes in a rocky outcrop in semi-arid Northeastern Brazil. Rev Biol Trop. 2015;63:827-43 pubmed
    ..Allophylus quercifolius (Mart.) Radlk. (Capparaceae) and Lafoensia pacari A. St.-Hil...
  50. Lee T, Ellimoottil C, Marchetti K, Banerjee T, Ivancic V, Kraft K, et al. Impact of Clinical Guidelines on Voiding Cystourethrogram Use and Vesicoureteral Reflux Incidence. J Urol. 2018;199:831-836 pubmed publisher
    ..Using an administrative claims database (Clinformatics™ Data Mart) children who underwent voiding cystourethrogram studies or had a diagnosis of vesicoureteral reflux between 2001 ..
  51. de Souza C, da Silva A, Gomez M, Rolóm M, Coronel C, da Costa J, et al. Anti-Trypanosoma, anti-Leishmania and cytotoxic activities of natural products from Psidium brownianum Mart. ex DC. and Psidium guajava var. Pomifera analysed by LC-MS. Acta Trop. 2017;176:380-384 pubmed publisher
    ..infantum parasite cell lines indicating these species as an alternative therapy given their efficacy in the in vitro assays performed, opening the possibility for new biological studies to further this knowledge through in vivo assays. ..
  52. de Freitas A, Kaplum V, Rossi D, da Silva L, Melhem M, Taborda C, et al. Proanthocyanidin polymeric tannins from Stryphnodendron adstringens are effective against Candida spp. isolates and for vaginal candidiasis treatment. J Ethnopharmacol. 2018;216:184-190 pubmed publisher
    The stem bark of Stryphnodendron adstringens (Mart.) Coville is popularly used as anti-inflammatory, astringent and in the treatment of wounds and vaginal infections...
  53. Costa A, Sousa J, da Silva M, Garruti D, Madruga M. Sensory and volatile profiles of monofloral honeys produced by native stingless bees of the brazilian semiarid region. Food Res Int. 2018;105:110-120 pubmed publisher
    ..subnitida Ducke and M. scutellaris Latrelle in typical flowering of the Brazilian semi-arid Ziziphus juazeiro Mart (juazeiro), Croton heliotropiifolius Kunth (velame branco) and Mimosa arenosa willd Poir (jurema branca) were ..
  54. Lee J, Soung Y, Young Kim S, Woo Nam S, Sang Park W, Young Lee J, et al. Mutational analysis of proapoptotic ARTS P-loop domain in common human cancers. Pathol Res Pract. 2006;202:67-70 pubmed
    Mounting evidence indicates that deregulation of apoptosis is involved in mechanisms of cancer development. ARTS is released from mitochondria into the cytosol during apoptosis, promoting caspase activation by neutralizing the inhibition ..
  55. Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K. SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling. Hum Mutat. 2007;28:1005-13 pubmed
    ..262C>T/p.Arg88Trp in SEPT9_v3). We found both sequence variants, but not the wild type, to form filaments with SEPT4 along stress fibers in mesenchymal mouse mammary gland NMuMG cells...
  56. Teles C, Moreira Dill L, Silva A, Facundo V, De Azevedo W, da Silva L, et al. A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro. BMC Complement Altern Med. 2015;15:165 pubmed publisher
    ..Moreover, this study opens major prospects for the development of novel chemotherapeutic agents with leishmanicidal activity. ..
  57. Barbosa P, Pala D, Silva C, de Souza M, do Amaral J, Vieira R, et al. Açai (Euterpe oleracea Mart.) pulp dietary intake improves cellular antioxidant enzymes and biomarkers of serum in healthy women. Nutrition. 2016;32:674-80 pubmed publisher
    ..These results show the antioxidant benefit of dietary açai for the healthy women included in the present study, and may increase understanding of the beneficial health properties of this fruit. ..
  58. Cunha Santino M, Fushita A, Peret A, Bianchini Júnior I. Morphometry and retention time as forcing functions to establishment and maintenance of aquatic macrophytes in a tropical reservoir. Braz J Biol. 2016;76:673-85 pubmed publisher
    ..Verdec, Salvinia auriculata Aubl., Eichhornia azurea (Sw.) Kunth, Eleocharis sp1, Eichhornia crassipes (Mart.) Solms, Oxycaryum cubense (Poepp. & Kunth) Lye) always were present and were more frequent in the sites...
  59. Narita J, Moraes G. A new species of Epicriopsis Berlese (Acari: Mesostigmata: Ameroseiidae) from Brazil, with a key to the world species of the genus. Zootaxa. 2016;4114:477-84 pubmed publisher
    ..Lodd. ex Mart.; Arecaceae) in Minas Gerais state, southeastern Brazil...
  60. Gannon P, Baumgaertner P, Huber A, Iancu E, Cagnon L, Abed Maillard S, et al. Rapid and Continued T-Cell Differentiation into Long-term Effector and Memory Stem Cells in Vaccinated Melanoma Patients. Clin Cancer Res. 2017;23:3285-3296 pubmed publisher
    ..We have previously shown that serial vaccinations with Melan-AMART-126-35 peptide, CpG-B, and incomplete Freund adjuvant (IFA) generated robust tumor-specific CD8 T-..
  61. Sobral Souza C, Silva A, Leite N, Costa J, Menezes I, Cunha F, et al. LC-MS analysis and cytoprotective effect against the mercurium and aluminium toxicity by bioactive products of Psidium brownianum Mart. ex DC. J Hazard Mater. 2019;370:54-62 pubmed publisher
    This study aimed to verify the chelating, antioxidant and cytoprotective activities of Psidium brownianum Mart. Ex DC against mercury and aluminum...
  62. Ruben J, Bontkes H, Westers T, Hooijberg E, Ossenkoppele G, de Gruijl T, et al. Differential capacity of human interleukin-4 and interferon-α monocyte-derived dendritic cells for cross-presentation of free versus cell-associated antigen. Cancer Immunol Immunother. 2015;64:1419-27 pubmed publisher
    ..Whereas IFNα MoDC were more potent in their capacity to cross-present a 25-mer MART-1 synthetic long peptide (SLP) to a MART-1aa26-35 recognizing CD8(+) T cell line, IL-4 MoDC proved more potent ..
  63. Jakobiec F. Conjunctival Primary Acquired Melanosis: Is It Time for a New Terminology?. Am J Ophthalmol. 2016;162:3-19.e1 pubmed publisher
    ..Standard hematoxylin-eosin-stained sections and immunohistochemical stains for MART-1, HMB-45, microphthalmia-associated transcription factor (MiTF), and Ki-67 for calculating the proliferation index ..
  64. Rosa F, Arruda A, Siqueira E, Arruda S. Phytochemical Compounds and Antioxidant Capacity of Tucum-Do-Cerrado (Bactris setosa Mart), Brazil's Native Fruit. Nutrients. 2016;8:110 pubmed publisher
    ..Although flavonoids are the main compounds identified in tucum-do-cerrado peel, other phenolics identified in minor amounts, such as phenolic acids and stilbenes, may be responsible for the high antioxidant capacity of the fruit. ..
  65. Zhao M, Wang Y, Zhou Z, Wang R, Guo J, Wan F. Effects of Periodically Repeated Heat Events on Reproduction and Ovary Development of Agasicles hygrophila (Coleoptera: Chrysomelidae). J Econ Entomol. 2016;109:1586-94 pubmed publisher summer resulted in difficulties in effectively controlling the population of Alternanthera philoxeroides (Mart.) Griseb (Amaranthaceae). Previous studies have largely ignored more natural, fluctuating conditions...
  66. Moraes M, Kubota T, Silva E, Silva A, Cambuim J, Moraes M, et al. Short Communication Mendelian inheritance, linkage, and genotypic disequilibrium in microsatellite loci of Hymenaea stigonocarpa Mart. ex Hayne (Fabaceae-Caesalpinioideae). Genet Mol Res. 2016;15: pubmed publisher
    ..We detected no evidence of genotypic disequilibrium between the loci in the adult trees or juveniles. Thus, our results suggest that these loci can be used with great accuracy in future genetic analyses of H. stigonocarpa populations. ..
  67. Feng H, Li G, Du S, Yang S, Li X, de Figueiredo P, et al. The septin protein Sep4 facilitates host infection by plant fungal pathogens via mediating initiation of infection structure formation. Environ Microbiol. 2017;19:1730-1749 pubmed publisher
    ..Here, we demonstrate that a conserved septin gene SEP4 plays crucial roles in this process...
  68. Yu Q, Scribner R, Leonardi C, Zhang L, Park C, Chen L, et al. Exploring racial disparity in obesity: A mediation analysis considering geo-coded environmental factors. Spat Spatiotemporal Epidemiol. 2017;21:13-23 pubmed publisher
    ..Results from generalized linear models (GLM) were compared with those from multiple additive regression trees (MART) which allow for hierarchical data structure, and fitting of nonlinear and complex interactive relationships...
  69. Tanaka M, Kijima H, Itoh J, Matsuda T, Tanaka T. Impaired expression of a human septin family gene Bradeion inhibits the growth and tumorigenesis of colorectal cancer in vitro and in vivo. Cancer Gene Ther. 2002;9:483-8 pubmed
    We have identified a novel human septin family gene Bradeion, which is specifically expressed in human colorectal cancer and malignant melanoma...
  70. Bornstein B, Edison N, Gottfried Y, Lev T, Shekhtman A, Gonen H, et al. X-linked Inhibitor of Apoptosis Protein promotes the degradation of its antagonist, the pro-apoptotic ARTS protein. Int J Biochem Cell Biol. 2012;44:489-95 pubmed publisher
    b>ARTS (Sept4_i2) is a mitochondrial pro-apoptotic tumor suppressor protein...
  71. de Almeida G, Ramos M, Araújo E, Baldauf C, Albuquerque U. Human perceptions of landscape change: The case of a monodominant forest of Attalea speciosa Mart ex. Spreng (Northeast Brazil). Ambio. 2016;45:458-67 pubmed publisher
    ..speciosa forest. Furthermore, other forms of landscape management resulting from human population growth may also have affected the current and past distribution of this forest. ..
  72. Chiang K, Yeh C, Pang J, Hsu J, Yeh T, Chen L, et al. 1?,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Growth Through Induction of G0/G1 Cell-cycle Arrest and Apoptosis. Anticancer Res. 2016;36:3307-13 pubmed
    ..receptor (VDR) and VDR expression increased with increasing exposure to 1?,25-dihydroxyvitamin D3 [1?,25(OH)2D3] or MART-10, a 1?,25(OH)2D3 analog...
  73. Marshall D, Salciccioli J, Goodson R, Pimentel M, Sun K, Celi L, et al. The association between sodium fluctuations and mortality in surgical patients requiring intensive care. J Crit Care. 2017;40:63-68 pubmed publisher
    ..We performed a retrospective analysis of the Medical Information Mart for Intensive Care II database...
  74. Gilchrist Scott D, Feinstein J, Agrawal R. Medicaid Managed Care Structures and Care Coordination. Pediatrics. 2017;140: pubmed publisher
    ..from the 2011/2012 National Survey of Children's Health and the Medicaid Statistical Information System state data mart, we conducted a retrospective, cross-sectional analysis of the relationships between fee-for-service, PCCM or HMO ..
  75. Ricardo L, Dias B, Mügge F, Leite V, Brandão M. Evidence of traditionality of Brazilian medicinal plants: The case studies of Stryphnodendron adstringens (Mart.) Coville (barbatimão) barks and Copaifera spp. (copaíba) oleoresin in wound healing. J Ethnopharmacol. 2018;219:319-336 pubmed publisher
    ..of Brazilian plants was demonstrated using data about barbatimão barks (Stryphnodendron adstringens (Mart.) Coville - Fabaceae) and Copaiba oleoresin (Copaifera spp. - Fabaceae) in wound healing, was established...
  76. Machado A, Santos A, Martins G, Cruz R, Costa M, Campina F, et al. Antiparasitic effect of the Psidium guajava L. (guava) and Psidium brownianum MART. EX DC. (araçá-de-veado) extracts. Food Chem Toxicol. 2018;119:275-280 pubmed publisher
    ..and P. brownianum Mart ex DC leaves were investigated regarding their antiparasitic effect and cytotoxic potential...
  77. Cohen B, Vawdrey D, Liu J, Caplan D, Furuya E, Mis F, et al. Challenges Associated With Using Large Data Sets for Quality Assessment and Research in Clinical Settings. Policy Polit Nurs Pract. 2015;16:117-24 pubmed publisher
    ..In this article, we describe our experience with assembling a data-mart and conducting clinical research using electronic data from four facilities within a single hospital network in New ..
  78. Chiang K, Yeh T, Chen S, Pang J, Yeh C, Hsu J, et al. The Vitamin D Analog, MART-10, Attenuates Triple Negative Breast Cancer Cells Metastatic Potential. Int J Mol Sci. 2016;17: pubmed publisher
    ..Thus, to develop a new regimen to attenuate TNBC metastatic potential is urgently needed. MART-10 (19-nor-2?-(3-hydroxypropyl)-1?,25(OH)?D?), the newly-synthesized 1?,25(OH)?D? analog, has been shown to be much ..
  79. Edison N, Curtz Y, Paland N, Mamriev D, Chorubczyk N, Haviv Reingewertz T, et al. Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis. Cell Rep. 2017;21:442-454 pubmed publisher
    ..Bcl-2 ubiquitylation is reduced in both XIAP- and Sept4/ARTS-deficient MEFs, demonstrating that XIAP serves as an E3 ligase for Bcl-2 and that ARTS is essential for this ..
  80. Hara L, Guirguis R, Hummel K, Villanueva M. More Than Bar Codes: Integrating Global Standards-Based Bar Code Technology Into National Health Information Systems in Ethiopia and Pakistan to Increase End-to-End Supply Chain Visibility. Glob Health Sci Pract. 2017;5:678-685 pubmed publisher
    ..the team to scan bar codes using the mobile phone's camera and to push the captured data to the country's data mart. Real-time tracking and tracing occurred from the central warehouse to the Addis Ababa distribution hub and to 2 ..
  81. Gannon P, Wieckowski S, Baumgaertner P, Hebeisen M, Allard M, Speiser D, et al. Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence. J Immunol. 2015;195:356-66 pubmed publisher
    ..n = 139) derived from seven melanoma patients vaccinated with IFA, CpG, and the native/EAA or analog/ELA Melan-A(MART-1)(26-35) peptide, binding with low or high affinity to MHC, respectively...
  82. Egydio Brandão A, Furlan C, Dos Santos D. Genetic Diversity and Structure of Populations of Annona crassiflora Mart. of Brazilian Savanna and Its Association with Chemical Variability. Chem Biodivers. 2016;13:990-7 pubmed publisher
    Annona crassiflora Mart. is a native tree from Brazilian savanna. Isoquinoline alkaloids are characteristic of species of Annonaceae. This work aimed to assess the magnitude of genetic diversity among different populations of A...
  83. Kaplan C, Steinmann M, Zapiórkowska N, Ewers H. Functional Redundancy of Septin Homologs in Dendritic Branching. Front Cell Dev Biol. 2017;5:11 pubmed publisher
    ..In neurons expressing SEPT5-shRNA, simultaneously expressed SEPT2-GFP, and SEPT4-GFP colocalize with SEPT7 at dendritic spine necks and rescue dendritic branching...
  84. Rodrigues P, Dutra Gomes J, Jamal C, Cunha Neto Ã, Santos M, Fagg C, et al. Triterpenes from Pouteria ramiflora (Mart.) Radlk. Leaves (Sapotaceae). Food Chem Toxicol. 2017;109:1063-1068 pubmed publisher
    Pouteria ramiflora (Mart.) Radlk. (Sapotaceae) is a species used by inhabitants from the Cerrado for its edible fruits and medicinal value...
  85. Nardeli S, Artico S, Aoyagi G, de Moura S, da Franca Silva T, Grossi de Sa M, et al. Genome-wide analysis of the MADS-box gene family in polyploid cotton (Gossypium hirsutum) and in its diploid parental species (Gossypium arboreum and Gossypium raimondii). Plant Physiol Biochem. 2018;127:169-184 pubmed publisher
    ..qPCR analysis revealed the expression patterns of putative homologs in the AP1, AP3, AGL6, SEP4, AGL15, AG, AGL17, TM8, SVP, SOC and TT16 subfamilies of G. hirsutum...
  86. Mandel Gutfreund Y, Kosti I, Larisch S. ARTS, the unusual septin: structural and functional aspects. Biol Chem. 2011;392:783-90 pubmed publisher
    The human Septin 4 gene (Sept4) encodes two major protein isoforms; Sept4_i1 (H5/PNUTL2) and Sept4_i2/ARTS...
  87. Kuo Y, Shen Y, Chen H, Lin Y, Wang Y, Chen Y, et al. SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins. J Cell Sci. 2015;128:923-34 pubmed publisher
    ..Here, we found that SEPT12 formed a filamentous structure with SEPT7, SEPT 6, SEPT2 and SEPT4 at the sperm annulus...
  88. da Cunha M, Arruda S. Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating SIRT1-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. Nutrients. 2017;9: pubmed publisher
    ..This study investigated the effect of tucum-do-cerrado (Bactris setosa Mart.) consumption on the expression of sirtuins (SIRT 1 and 3) and senescence marker protein-30 (SMP30), and on the ..
  89. Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, et al. A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nat Cell Biol. 2000;2:915-21 pubmed
    Here we describe a protein product of the human septin H5/PNUTL2/CDCrel2b gene, which we call ARTS (for apoptosis-related protein in the TGF-beta signalling pathway)...
  90. Chung C, Kanetsky P, Wang Z, Hildebrandt M, Koster R, Skotheim R, et al. Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nat Genet. 2013;45:680-5 pubmed publisher
    ..These new TGCT susceptibility loci contain biologically plausible genes encoding proteins important for male germ cell development, chromosomal segregation and the DNA damage response. ..
  91. Vega I, Hsu S. The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells. Neuroreport. 2003;14:31-7 pubmed
    ..Taken together, these findings suggest that Nedd5 may be required for polarized neurite outgrowth, perhaps, by facilitating the exocyst complex function during neuronal differentiation. ..
  92. Ihara M, Tomimoto H, Kitayama H, Morioka Y, Akiguchi I, Shibasaki H, et al. Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. J Biol Chem. 2003;278:24095-102 pubmed
    ..Here we report that Sept4, a member of the septin protein family, is consistently found in these inclusions, whereas five other septins (..