SEM1

Summary

Gene Symbol: SEM1
Description: SEM1, 26S proteasome complex subunit
Alias: C7orf76, DSS1, ECD, SHFD1, SHFM1, SHSF1, Shfdg1, 26S proteasome complex subunit SEM1, 26S proteasome complex subunit DSS1, deleted in split hand/split foot protein 1, deleted in split-hand/split-foot 1, split hand/foot deleted protein 1, split hand/foot malformation (ectrodactyly) type 1, split hand/foot malformation type 1 protein
Species: human
Products:     SEM1

Top Publications

  1. Wei S, Williams J, Dang H, Darden T, Betz B, Humble M, et al. Identification of a specific motif of the DSS1 protein required for proteasome interaction and p53 protein degradation. J Mol Biol. 2008;383:693-712 pubmed publisher
    Deleted in Split hand/Split foot 1 (DSS1) was previously identified as a novel 12-O-tetradecanoylphorbol-13-acetate (TPA)-inducible gene with possible involvement in early event of mouse skin carcinogenesis...
  2. Roberts S, Hughes H, Davies S, Meredith A. Bilateral split hand and split foot malformation in a boy with a de novo interstitial deletion of 7q21.3. J Med Genet. 1991;28:479-81 pubmed
  3. Crackower M, Scherer S, Rommens J, Hui C, Poorkaj P, Soder S, et al. Characterization of the split hand/split foot malformation locus SHFM1 at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development. Hum Mol Genet. 1996;5:571-9 pubmed
    ..An autosomal dominant form of this disorder (SHFM1) has been mapped to 7q21.3-q22.1 on the basis of SHFM-associated chromosomal rearrangements...
  4. Ma Y, Lin H, Chang F, Chang T, Trieu T, Pridgen H, et al. Identification of the deleted in split hand/split foot 1 protein as a novel biomarker for human cervical cancer. Carcinogenesis. 2013;34:68-78 pubmed publisher
    ..In this work, we have identified deleted in split hand/split foot 1 protein (DSS1) as an early biomarker that is specifically upregulated in premalignant and malignant cervical epithelial cells, ..
  5. Li J, Zou C, Bai Y, Wazer D, Band V, Gao Q. DSS1 is required for the stability of BRCA2. Oncogene. 2006;25:1186-94 pubmed
    b>DSS1 is an evolutionarily conserved acidic protein that binds to BRCA2. However, study of the function of DSS1 in mammalian cells has been hampered because endogenous DSS1 has not been detectable by Western blotting...
  6. Wang S, Jing H, Yang H, Liu Z, Guo H, Chai L, et al. Tanshinone I selectively suppresses pro-inflammatory genes expression in activated microglia and prevents nigrostriatal dopaminergic neurodegeneration in a mouse model of Parkinson's disease. J Ethnopharmacol. 2015;164:247-55 pubmed publisher
    ..of cytokines in the midbrain were investigated by the rotarod test, high-performance liquid chromatography (HPLC)-ECD, immunohistochemistry and Elisa. 1-methyl-4-phenylpyridinium (MPP+) concentration was tested by HPLC...
  7. Wu D, Wang S, Wen X, Han X, Wang Y, Shen M, et al. Inhibition of microRNA-200a Upregulates the Expression of Striatal Dopamine Receptor D2 to Repress Apoptosis of Striatum via the cAMP/PKA Signaling Pathway in Rats with Parkinson's Disease. Cell Physiol Biochem. 2018;51:1600-1615 pubmed publisher
    ..High-performance liquid chromatography-electrochemical detection (HPLC-ECD) was employed to detect the levels of dopamine, 3, 4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA),..
  8. Tang Y, Yue Z, Xin D, Zeng L, Xiong Z, Hu Z, et al. ??Ecdysterone promotes autophagy and inhibits apoptosis in osteoporotic rats. Mol Med Rep. 2017;: pubmed publisher
    ..the effects of glucocorticoid?induced osteoporosis on osteoblasts and to examine the roles of ??ecdysterone (??Ecd) involved...
  9. Mazor R, Manevich Mazor M, Kesler A, Aizenstein O, Eshed I, Jaffe R, et al. Clinical considerations and key issues in the management of patients with Erdheim-Chester Disease: a seven case series. BMC Med. 2014;12:221 pubmed publisher
    Erdheim-Chester Disease (ECD), a non Langerhans' cell histiocytosis of orphan nature and propensity for multi-systemic presentations, comprises an intricate medical challenge in terms of diagnosis, treatment and complication management...

More Information

Publications142 found, 100 shown here

  1. Huang Y, Cui S, Cui X, Cao Q, Ding H, Song J, et al. Tetrandrine, an alkaloid from S. tetrandra exhibits anti-hypertensive and sleep-enhancing effects in SHR via different mechanisms. Phytomedicine. 2016;23:1821-1829 pubmed publisher
    ..The level of norepinephrine (NE) was detected by HPLC-ECD. Amlodipine (100mg/kg, i.g...
  2. Kobayashi R, Hayashi H, Kawakatsu S, Ishiki A, Okamura N, Arai H, et al. [18F]THK-5351 PET imaging in early-stage semantic variant primary progressive aphasia: a report of two cases and a literature review. BMC Neurol. 2018;18:109 pubmed publisher
    ..Technetium-99-ethyl cysteinate dimer ([99mTc]ECD) SPECT revealed hypoperfusion in the left temporal lobe...
  3. Hayashi Y, Iwasaki Y, Takekoshi A, Yoshikura N, Asano T, Mimuro M, et al. An autopsy-verified case of FTLD-TDP type A with upper motor neuron-predominant motor neuron disease mimicking MM2-thalamic-type sporadic Creutzfeldt-Jakob disease. Prion. 2016;10:492-501 pubmed
    ..Brain diffusion MRI did not reveal abnormal changes. An easy Z score (eZIS) analysis for 99mTc-ECD-single photon emission computed tomography (99mTc-ECD-SPECT) revealed a bilateral decrease in thalamic ..
  4. Nakagawa Y, Ikeda M, Ando T, Tasaki M, Saito K, Takahashi K, et al. Re-evaluating Cut-off Points for the Expansion of Deceased Donor Criteria for Kidney Transplantation in Japan. Transplant Proc. 2017;49:10-15 pubmed publisher
    ..In response, the concept of the expanded criteria donor (ECD) has been defined to include donors with traditionally less favorable characteristics...
  5. Lingeshwar P, Kaur G, Singh N, Singh S, Mishra A, Shukla S, et al. A study on the involvement of GABA-transaminase in MCT induced pulmonary hypertension. Pulm Pharmacol Ther. 2016;36:10-21 pubmed publisher
    ..The levels of plasma NE (by High performance liquid chromatography coupled with electrochemical detector; HPLC-ECD) and lung GABA (by liquid chromatography-mass spectrometry) were also estimated...
  6. Varun C, Dineshkumar T, Jayant V, Rameshkumar A, Rajkumar K, Rajashree P, et al. Salivary Her2/neu Levels in Differentiation of Oral Premalignant Disorders and Oral Squamous Cell Carcinomas. Asian Pac J Cancer Prev. 2015;16:5773-7 pubmed
    ..The HER2 extracellular domain (HER2 ECD) levels were measured using ELISA...
  7. Campochiaro C, Tomelleri A, Cavalli G, Berti A, Dagna L. Erdheim-Chester disease. Eur J Intern Med. 2015;26:223-9 pubmed publisher
    Erdheim-Chester disease (ECD) is rare form of non-Langerhans cells histiocytosis with multiorgan involvement. Individuals are more frequently affected in their fifth decade and there is a slight male prevalence...
  8. Pyrzanowska J, Fecka I, Mirowska Guzel D, Joniec Maciejak I, Blecharz Klin K, Piechal A, et al. Long-term administration of Aspalathus linearis infusion affects spatial memory of adult Sprague-Dawley male rats as well as increases their striatal dopamine content. J Ethnopharmacol. 2019;238:111881 pubmed publisher
    ..levels (DOPAC, 3-MT, HVA, MHPG, 5-HIAA) were quantified in prefrontal cortex, hippocampus and striatum by HPLC-ECD. Body weight and blood glucose level were additionally estimated...
  9. Hayashi Y, Iwasaki Y, Yoshikura N, Asano T, Hatano T, Tatsumi S, et al. Decreased regional cerebral blood flow in the bilateral thalami and medulla oblongata determined by an easy Z-score (eZIS) analysis of (99m)Tc-ECD-SPECT images in a case of MM2-thalamic-type sporadic Creutzfeldt-Jakob disease. J Neurol Sci. 2015;358:447-52 pubmed publisher
    ..easy Z-score (eZIS) analysis for (99m)Tc-ethyl cysteinate dimer-single photon emission computed tomography ((99m)Tc-ECD-SPECT) revealed decreased regional cerebral blood flow in the bilateral thalami and medulla oblongata...
  10. Pan Z, Niu Y, Liang Y, Zhang X, Dong M. ?-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38(MAPK)-p53 Signaling Pathway. Neurotox Res. 2016;30:453-66 pubmed publisher
    ..No curative therapy is available for PD. We recently found that phytoestrogen ?-ecdysterone (?-Ecd) is able to reduce MPP(+)-induced apoptosis in PC12 cells...
  11. Suntravat M, Helmke T, Atphaisit C, Cuevas E, Lucena S, Uzcategui N, et al. Expression, purification, and analysis of three recombinant ECD disintegrins (r-colombistatins) from P-III class snake venom metalloproteinases affecting platelet aggregation and SK-MEL-28 cell adhesion. Toxicon. 2016;122:43-49 pubmed publisher
    ..Here, three new cDNAs encoding ECD disintegrin-like domains of metalloproteinase precursor sequences obtained from a Venezuelan mapanare (Bothrops ..
  12. Guo S, Yan Q, Rohr J, Wang Y, Fan L, Wang Z. Erdheim-Chester disease involving the breast--a rare but important differential diagnosis. Hum Pathol. 2015;46:159-64 pubmed publisher
    Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by multisystem infiltration by foamy histiocytes surrounded by fibrosis...
  13. Thanan R, Pairojkul C, Pinlaor S, Khuntikeo N, Wongkham C, Sripa B, et al. Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis. Free Radic Biol Med. 2013;65:1464-1472 pubmed publisher
    ..in cholangiocarcinoma tissues analyzed by immunohistochemical staining, and measured 8-oxodG levels by using HPLC-ECD as an inflammation-related DNA lesion...
  14. Ji W, Li R, Li M, Wang S, Zhang X, Niu X, et al. Antidepressant-like effect of essential oil of Perilla frutescens in a chronic, unpredictable, mild stress-induced depression model mice. Chin J Nat Med. 2014;12:753-9 pubmed publisher
    ..5-HT) and its metabolite, 5-hydroxyindoleacetic acid (5-HIAA), in mouse hippocampus were determined by HPLC-ECD. Serum interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)-α levels were evaluated by enzyme-linked ..
  15. Ramos Zaldívar H, Martínez Irías D, Espinoza Moreno N, Napky Rajo J, Bueso Aguilar T, Reyes Perdomo K, et al. A novel description of a syndrome consisting of 7q21.3 deletion including DYNC1I1 with preserved DLX5/6 without ectrodactyly: a case report. J Med Case Rep. 2016;10:156 pubmed publisher
    Chromosomal region 7q21.3 comprises approximately 5.2 mega base pairs that include genes DLX5/6, SHFM1, and DYNC1I1 associated with split hand/split foot malformation 1...
  16. Christophi G, Sharma Y, Farhan Q, Jain U, Walker T, Sayuk G, et al. Erdheim-Chester Disease presenting with histiocytic colitis and cytokine storm. J Gastrointestin Liver Dis. 2017;26:183-187 pubmed publisher
    ..Erdheim-Chester Disease (ECD) is a rare type of non-Langerhans cell histiocytosis characterized by tissue inflammation and injury caused by ..
  17. Crider T, Eng D, Sarkar P, Cordero J, Krusz J, Sarkar S. Microvascular and large vein abnormalities in young patients after mild head trauma and associated fatigue: A brain SPECT evaluation and posture dependence modeling. Clin Neurol Neurosurg. 2018;170:159-164 pubmed publisher
    ..prior to trauma were prospectively studied following onset of fatigue 6-12 months after mTBI utilizing 99?m-Tc ECD brain SPECT with early and delayed radiotracer imaging...
  18. Lee S, Booe J, Gingell J, Sjoelund V, Hay D, Pioszak A. N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity. Biochemistry. 2017;56:3380-3393 pubmed publisher
    ..role of CTR N-glycosylation in hormone binding using purified calcitonin and amylin receptor extracellular domain (ECD) glycoforms and fluorescence polarization/anisotropy and isothermal titration calorimetry peptide-binding assays...
  19. Clarke D, Campopiano D. Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution. Analyst. 2015;140:2679-86 pubmed publisher
    ..solution greatly improved the quality of the data obtained from native top-down electron-capture dissociation (ECD) experiments...
  20. Zhang L, Yang J, Luo Y, Shang J, Jiang X. Simultaneous determination of eleven compounds related to metabolism of bioamines in rat cortex and hippocampus by HPLC-ECD with boron-doped diamond working electrode. J Pharm Biomed Anal. 2016;118:41-51 pubmed publisher
    ..These eleven compounds in cortices and hippocampi were compared, which was used for monitoring their variations in neuroscience research. ..
  21. Cao Q, Jiang Y, Cui S, Tu P, Chen Y, Ma X, et al. Tenuifolin, a saponin derived from Radix Polygalae, exhibits sleep-enhancing effects in mice. Phytomedicine. 2016;23:1797-1805 pubmed publisher
    ..High performance liquid chromatograph- electrochemical detection (HPLC-ECD) and ultrafast liquid chromatography-mass spectrometry (UFLC-MS) were used for the detection of neurotransmitters...
  22. Johnson K, Gagnon L, Tian C, Longo Guess C, Low B, Wiles M, et al. Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice. Genetics. 2018;208:1165-1179 pubmed publisher
    ..i>Slc25a13hspn/hspn mice provide a new animal model for studying long-range enhancer effects on Dlx5 expression in the developing inner ear. ..
  23. de Sena Tomás C, Sutherland J, Milisavljevic M, Nikolić D, Pérez Martín J, Kojic M, et al. LAMMER kinase contributes to genome stability in Ustilago maydis. DNA Repair (Amst). 2015;33:70-7 pubmed publisher
    ..However, overexpressing the gene for Rad51, its regulator Brh2, or the Brh2 regulator Dss1 partially restored genotoxin resistance of the lkh1Δ and lkh1(Q488*) mutants...
  24. Laham G, Scuteri R, Cornicelli P, Arriola M, Raffaele P, Davalos Michel M, et al. Surveillance Registry of Sirolimus Use in Recipients of Kidney Allografts From Expanded Criteria Donors. Transplant Proc. 2016;48:2650-2655 pubmed publisher
    The use of expanded criteria donor (ECD) kidneys has increased the overall availability of renal transplants. This study assessed the use of sirolimus in patients receiving Argentina-ECD kidneys...
  25. Zou Y, Wang R, Guo H, Dong M. Phytoestrogen β-Ecdysterone Protects PC12 Cells Against MPP+-Induced Neurotoxicity In Vitro: Involvement of PI3K-Nrf2-Regulated Pathway. Toxicol Sci. 2015;147:28-38 pubmed publisher
    ..this study is to evaluate the hypothesis that the neuroprotective effects of phytoestrogen β-ecdysterone (β-Ecd) might mainly result from its antioxidant capability by the activation of the phosphoinositide-3-kinase (PI3K)-..
  26. Zhang T, Xue R, Zhu L, Li J, Fan Q, Zhong B, et al. Evaluation of the analgesic effects of ammoxetine, a novel potent serotonin and norepinephrine reuptake inhibitor. Acta Pharmacol Sin. 2016;37:1154-65 pubmed publisher
    ..The contents of 5-HT and NE in brain regions of fibromyalgia rats were measured using HPLC-ECD. In all the experiments, duloxetine was used as a positive control drug. Oral administration of ammoxetine (0...
  27. Abbasi Y, Mannaerts C. Evaluating organochlorine pesticide residues in the aquatic environment of the Lake Naivasha River basin using passive sampling techniques. Environ Monit Assess. 2018;190:349 pubmed publisher
    ..from the sampling media, the residues were analyzed using gas chromatography electron capture detection (GC-ECD) for the OCPs and gas chromatography-mass spectrometry (GC-MS) for the PCB reference compounds...
  28. Zhang Y, Liu Y, Li Y, Li L, Ma S, Qu J, et al. Terpenoids from the roots of Alangium chinense. J Asian Nat Prod Res. 2015;17:1025-38 pubmed publisher
    ..The absolute configurations of 1-6 were assigned by experimental and calculated ECD spectra. The skeleton of the compounds (1 and 2) has been reported only one time so far...
  29. Marty A, Burillon C, Desanlis A, Damour O, Kocaba V, Auxenfans C. Validation of an endothelial roll preparation for Descemet Membrane Endothelial Keratoplasty by a cornea bank using "no touch" dissection technique. Cell Tissue Bank. 2016;17:225-32 pubmed publisher
    ..Endothelial cells densities (ECD) were evaluated before and after preparation, after storage and transport to the surgery room...
  30. Lin Z, Lin Z, Mu Y, Yan D. Comparison of collision-induced dissociation and electron-induced dissociation of phillyrin using FT-ICR MS. Spectrochim Acta A Mol Biomol Spectrosc. 2016;167:84-88 pubmed publisher
    ..cyclotron resonance mass spectrometry using collision-induced dissociation (CID) and electron capture dissociation (ECD) at high mass resolution was first applied to investigate the characteristic fragment ions of phillyrin...
  31. Fu P, Macmillan J. Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions. Org Biomol Chem. 2017;15:5275-5278 pubmed publisher
    ..The structure was fully determined by spectroscopic analysis, ECD calculations and chemical methods...
  32. Liao M, Shi Y, Cao H, Fang Q, Xiao J, Hua R. Migration and Accumulation of Octachlorodipropyl Ether in Soil-Tea Systems in Young and Old Tea Gardens. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..ether (OCDPE) in soil-tea systems were investigated using a gas chromatography-electron capture detector (GC-ECD) method in young and old tea gardens. When the residual concentration of OCDPE was 100 g a.i...
  33. Lv J, Yu S, Xin Y, Cheng R, Zhu H, Wang D, et al. Anti-viral and cytotoxic norbisabolane sesquiterpenoid glycosides from Phyllanthus emblica and their absolute configurations. Phytochemistry. 2015;117:123-34 pubmed publisher
    ..configurations of these compounds was facilitated by theoretical calculations of electronic circular dichroism (ECD) spectra using time-dependent density functional theory (TDDFT) for the aglycone components, and pre-column ..
  34. Wu G, Yu G, Kurtán T, Mándi A, Peng J, Mo X, et al. Versixanthones A-F, Cytotoxic Xanthone-Chromanone Dimers from the Marine-Derived Fungus Aspergillus versicolor HDN1009. J Nat Prod. 2015;78:2691-8 pubmed publisher
    ..helicities, were established by a combination of X-ray diffraction analysis, chemical conversions, and TDDFT-ECD calculations...
  35. Aust G, Zhu D, Van Meir E, Xu L. Adhesion GPCRs in Tumorigenesis. Handb Exp Pharmacol. 2016;234:369-396 pubmed
    ..the regulation of angiogenesis by releasing soluble fragments following the cleavage of their extracellular domain (ECD) at the conserved GPCR-proteolytic site (GPS) or other more distal cleavage sites as typical for the ADGRB (BAI) ..
  36. Gauthier A, Garcin T, Thuret G, He Z, Jullienne R, Trone M, et al. Very early endothelial cell loss after penetrating keratoplasty with organ-cultured corneas. Br J Ophthalmol. 2017;101:1113-1118 pubmed publisher
    ..a quantification of the difference between ebECD performed 2?days before graft and very early postoperative ECD. (2) Ten pairs of corneas with comparable ebECD in both corneas and same organ-culture (OC) duration were ..
  37. Coronado Aceves E, Gigliarelli G, Garibay Escobar A, Zepeda R, Curini M, López Cervantes J, et al. New Isoflavonoids from the extract of Rhynchosia precatoria (Humb. & Bonpl. ex Willd.) DC. and their antimycobacterial activity. J Ethnopharmacol. 2017;206:92-100 pubmed publisher
    ..at the C-3 chiral center was established by quantum mechanical calculation of the electronic circular dichroism (ECD) spectrum. In vitro inhibitory and bactericidal activity against M. tuberculosis and M...
  38. Jiao S, Bu X, Liu Y, Wang Q, Liu C, Yao X, et al. Differential levels of p75NTR ectodomain in CSF and blood in patients with Alzheimer's disease: a novel diagnostic marker. Transl Psychiatry. 2015;5:e650 pubmed publisher
    ..The ectodomain of p75 neurotrophin receptor (p75NTR-ECD) has been suggested to play important roles in regulating beta-amyloid (Aβ) deposition and in protecting neurons ..
  39. Chen L, Zhu X, Shen J, Zhang W. Selective solid-phase extraction of catecholamines from plasma using nanofibers doped with crown ether and their quantitation by HPLC with electrochemical detection. Anal Bioanal Chem. 2016;408:4987-94 pubmed publisher
    ..sample cleanup method was verified by high-performance liquid chromatography with electrochemical detection (HPLC-ECD)...
  40. Martens de Kemp S, Brink A, van der Meulen I, de Menezes R, Te Beest D, Leemans C, et al. The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics. Mol Cancer Ther. 2017;16:540-550 pubmed publisher
    ..We also identified the involvement of the SHFM1 gene in the process of DNA cross-link repair...
  41. Farina Y, Abdullah M, Bibi N, Khalik W. Determination of pesticide residues in leafy vegetables at parts per billion levels by a chemometric study using GC-ECD in Cameron Highlands, Malaysia. Food Chem. 2017;224:55-61 pubmed publisher
    ..analytical method has been developed employing gas chromatography coupled with electron capture detector (GC-ECD), and validated for screening and quantification of 15 pesticide residues at trace levels in cabbage, broccoli, ..
  42. Pietroń W, Małagocki P. Quantification of polybrominated diphenyl ethers (PBDEs) in food. A review. Talanta. 2017;167:411-427 pubmed publisher
    ..b>ECD is the most sensitive technique; however, other halogen compounds present in sample may interfere with PBDEs ..
  43. Huang C, Hsu S, Chang Y, Huang S, Huang Y, Lee C, et al. Cerebral Perfusion Insufficiency and Relationships with Cognitive Deficits in Alzheimer's Disease: A Multiparametric Neuroimaging Study. Sci Rep. 2018;8:1541 pubmed publisher
    ..magnetic resonance imaging (ASL-MRI) and ethylcysteinate dimer single-photon emission computed tomography (ECD-SPECT) in 50 patients with AD and 30 age-matched controls to investigate how hypoperfusion patterns were associated ..
  44. Kobayashi A, Yokogawa H, Mori N, Sugiyama K. Case series and techniques of Descemet's Stripping Automated Endothelial Keratoplasty for severe bullous keratopathy after birth injury. BMC Ophthalmol. 2015;15:92 pubmed publisher
    ..Mean BCVA improved from 0.06 to 0.15 at 6 months and to 0.38 at 12 months. Postoperative ECD was 2270 cells/mm(2) (mean loss, 24.4 %) at 6 months and 2130 (mean loss, 29.1 %) at 12 months...
  45. DʼAprano A, Silburn S, Johnston V, Oberklaid F, Tayler C. Culturally Appropriate Training for Remote Australian Aboriginal Health Workers: Evaluation of an Early Child Development Training Intervention. J Dev Behav Pediatr. 2015;36:503-11 pubmed publisher
    This study aimed to design, implement, and evaluate training in early childhood development (ECD) and in the use of a culturally adapted developmental screening tool, for remote Australian Aboriginal Health Workers (AHWs) and other ..
  46. Van Schoors J, Viaene J, Van Wanseele Y, Smolders I, Dejaegher B, Vander Heyden Y, et al. An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples. J Pharm Biomed Anal. 2016;127:136-46 pubmed publisher
    ..A fast and sensitive microbore (1.0mm i.d. column) UHPLC method coupled to electrochemical detection (ECD) is developed by means of design of experiments with the emphasis on sufficient retention of NA within an ..
  47. Xu J, Xiao D, Song W, Chen L, Liu W, Xie N, et al. Quassinoids from the stems of Picrasma quassioides and their cytotoxic and NO production-inhibitory activities. Fitoterapia. 2016;110:13-9 pubmed publisher
    ..and absolute configurations for these compounds were achieved on the basis of ROESY spectra and quantum chemical ECD calculation...
  48. Pang D, Su X, Zhu Z, Sun J, Li Y, Song Y, et al. Flavonoid dimers from the total phenolic extract of Chinese dragon's blood, the red resin of Dracaena cochinchinensis. Fitoterapia. 2016;115:135-141 pubmed publisher
    ..absolute configurations were determined on the basis of experimental and calculated electronic circular dichroism (ECD) data...
  49. Liu H, Pan B, Liou G. Highly transparent AgNW/PDMS stretchable electrodes for elastomeric electrochromic devices. Nanoscale. 2017;9:2633-2639 pubmed publisher
    ..Furthermore, a novel elastomeric HV electrochromic device (ECD) fabricated based on these stretchable AgNW/PDMS hybrid electrodes exhibited excellent electrochromic behavior in ..
  50. Bernardino K, Pinto M, Bolzani V, de Moura A, Batista Junior J. Pinpointing disulfide connectivities in cysteine-rich proteins. Chem Commun (Camb). 2017;53:7337-7340 pubmed publisher
    ..It provides a detailed description of their dynamical and structural features, which can be used to perform ensemble-averaged ECD calculations. Plant cyclotides are used as model compounds.
  51. Oyewumi M, Manickavasagam D, Novak K, Wehrung D, Paulic N, Moussa F, et al. Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells. Oncotarget. 2016;7:13932-44 pubmed publisher
    ..as a therapeutic target for lung cancer will require a greater understanding of the impact of GPNMB/OA ectodomain (ECD) protein shedding into tumor tissues...
  52. Burlage L, Karimian N, Westerkamp A, Visser N, Matton A, van Rijn R, et al. Oxygenated hypothermic machine perfusion after static cold storage improves endothelial function of extended criteria donor livers. HPB (Oxford). 2017;19:538-546 pubmed publisher
    ..oxygenated hypothermic machine perfusion (HMP) on endothelial cell function of extended criteria donor (ECD) livers...
  53. Qin X, Shu T, Yu Q, Yan H, Ni W, An L, et al. Cytotoxic Acylphloroglucinol Derivatives from Callistemon salignus. Nat Prod Bioprospect. 2017;7:315-321 pubmed publisher
    ..were unambiguously established by a combination of NMR and MS analysis and electronic circular dichroism (ECD) evidence. Callisalignenes H (2) and I (3) have a rare sec-butyl moiety at C-7...
  54. Perez Escamilla R, Cavallera V, Tomlinson M, Dua T. Scaling up Integrated Early Childhood Development programs: lessons from four countries. Child Care Health Dev. 2018;44:50-61 pubmed publisher
    There is still limited knowledge regarding the translation of early child development (ECD) knowledge into effective policies and large-scale programmes...
  55. Kristensen C, Bystol K, Li B, Serrano L, Brenneman M. Depletion of DSS1 protein disables homologous recombinational repair in human cells. Mutat Res. 2010;694:60-4 pubmed publisher
    b>DSS1 is a small, highly acidic protein widely conserved among eukaryotes as a component of the 19S proteasome and implicated in ubiquitin-mediated proteolysis...
  56. Qi Y, Volmer D. Structural analysis of small to medium-sized molecules by mass spectrometry after electron-ion fragmentation (ExD) reactions. Analyst. 2016;141:794-806 pubmed publisher
    Electron capture dissociation (ECD) is a tandem mass spectrometry (MS/MS) method that utilizes the interaction of ions and electrons...
  57. Barni M, Ondarza P, Gonzalez M, Da Cuña R, Meijide F, Grosman F, et al. Persistent organic pollutants (POPs) in fish with different feeding habits inhabiting a shallow lake ecosystem. Sci Total Environ. 2016;550:900-909 pubmed publisher
    ..OCPs), polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) were determined by GC-ECD. Biotic and abiotic samples showed the same POPs distribution pattern: OCPs>PCBs>PBDEs...
  58. Ishii N, Yamaguchi T, Yazu H, Satake Y, Yoshida A, Shimazaki J. Factors associated with graft survival and endothelial cell density after Descemet's stripping automated endothelial keratoplasty. Sci Rep. 2016;6:25276 pubmed publisher
    ..of this study was to identify clinical factors affecting graft survival and postoperative endothelial cell density (ECD) after Descemet's stripping automated endothelial keratoplasty (DSAEK)...
  59. Jin W, Qin B, Chen Z, Liu H, Barve A, Cheng K. Discovery of PSMA-specific peptide ligands for targeted drug delivery. Int J Pharm. 2016;513:138-147 pubmed publisher
    ..Five rounds of biopanning against recombinant human PSMA extracellular domain (ECD), PSMA-positive LNCaP cells, and LNCaP xenografts in nude mice were conducted...
  60. Zinna F, Bruhn T, Guido C, Ahrens J, Bröring M, Di Bari L, et al. Circularly Polarized Luminescence from Axially Chiral BODIPY DYEmers: An Experimental and Computational Study. Chemistry. 2016;22:16089-16098 pubmed publisher
    ..The electronic circular dichroism (ECD) and CPL spectra of these atropisomeric dimers are dominated by the exciton coupling between the main ?-?* ..
  61. Sai C, Li D, Li S, Han T, Guo Y, Li Z, et al. LC-MS guided isolation of three pairs of enantiomeric alkaloids from Macleaya cordata and their enantioseparations, antiproliferative activity, apoptosis-inducing property. Sci Rep. 2017;7:15410 pubmed publisher
    ..by chiral HPLC, and the absolute configurations of enantiomers were determined by electronic circular dichroism (ECD) spectroscopy. Compounds 1-7 showed antiproliferative activity against HL-60 with IC50 values of 1.34-41...
  62. Biswas K, Hartman K, Yu C, Harrison O, Song H, Smith A, et al. E-cadherin junction formation involves an active kinetic nucleation process. Proc Natl Acad Sci U S A. 2015;112:10932-7 pubmed publisher
    ..structures between native E-cadherin in living cells and the extracellular domain of E-cadherin (E-cad-ECD) in a supported membrane...
  63. Xia M, Cui C, Li C, Wu C, Peng J, Li D. Rare Chromones from a Fungal Mutant of the Marine-Derived Penicillium purpurogenum G59. Mar Drugs. 2015;13:5219-36 pubmed publisher
    ..were determined by spectroscopic methods, especially by NMR analysis and electronic circular dichroism (ECD) experiments in conjunction with calculations...
  64. Amano S, Setogawa A, Inoue K. Evaluation of factors affecting visual acuity after Descemet stripping automated endothelial keratoplasty. Jpn J Ophthalmol. 2017;61:137-141 pubmed publisher
    ..cylinder, grade of preoperative corneal edema, preoperative graft thickness, and endothelial cell density (ECD) before and at 1, 3, 6, 12, and 24 months after surgery...
  65. Mahauad Fernandez W, Okeoma C. Cysteine-linked dimerization of BST-2 confers anoikis resistance to breast cancer cells by negating proapoptotic activities to promote tumor cell survival and growth. Cell Death Dis. 2017;8:e2687 pubmed publisher
    ..studies, we report that dimerization of BST-2 through cysteine residues located in the BST-2 extracellular domain (ECD), leads to anoikis resistance and cell survival through proteasome-mediated degradation of BIM-a key proapoptotic ..
  66. Sun L, Lai C, Wang C, Wang Y, Wang J, Hsu Y, et al. Risk factors for infective endocarditis in children with congenital heart diseases - A nationwide population-based case control study. Int J Cardiol. 2017;248:126-130 pubmed publisher
    ..58; 95% confidence interval, 5.38-17.05), endocardial cushion defect (ECD) (8.01; 2.73-23.50), Left-sided lesions (4.36; 1.90-10.01) and VSD (2.93; 1.64-5.23)...
  67. Wang H, Liu L, Liu F, Chen L, Qu X, Li J, et al. [Diagnostic Value of CD27 Antigen in Patients with Multiple Myeloma]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017;25:1069-1073 pubmed publisher
    ..Antibodies are as follows:ckappa-FITC/clambda-PE/ CD38-ECD/CD45-PERCP/CD19-PC7/ CD27-APC/CD138-BV421/ CD56-BV510...
  68. Wang Y, Ren Q, Yan Z, Wang W, Zhao L, Bai M, et al. Flavonoids and their derivatives with ?-amyloid aggregation inhibitory activity from the leaves and twigs of Pithecellobium clypearia Benth. Bioorg Med Chem Lett. 2017;27:4823-4827 pubmed publisher
    ..The absolute configurations of new compounds were assigned by comparing their experimental specific rotation or ECD curves with the calculated data...
  69. SÅ‚owik Borowiec M, Szpyrka E, Rupar J, Matyaszek A, Podbielska M. Pesticide residues in stone fruits from the south-eastern region of Poland in 2012-2104. Rocz Panstw Zakl Hig. 2015;66:211-6 pubmed
    ..liquid extraction coupled with gas chromatography with electron capture and nitrogen phosphorus detection (GC-ECD/NPD) and spectrophotometry (dithiocarbamates residues) were used for the analysis...
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    ..The coatings deposited using alternating potentials assisted electrochemical deposition (AP-ECD) showed significantly enhanced osteoblasts proliferation, and rhBMP-2 loading capability compared to those of the ..
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    ..electron impact ionization MS (EIMS), negative ion chemical ionization MS (NCIMS), and electron capture detection (ECD). Respective GC/EIMS LOQs for PPO, PCH-1, PCH-2, PBH-1, and PBH-2 in MTBE extracts were [ppm (μg/g nut)] 0.9, 2...
  72. Kihara Y, Nakamura Y, Yokoyama T, Konno O, Iwamoto H, Kawachi S. Study of Cadaveric Kidney Transplantation: A Single Center Experience. Transplant Proc. 2016;48:725-8 pubmed publisher
    ..from expanded-criteria donors (ECDs), and it is anticipated that there will be increases in the number of ECD kidney transplants...
  73. Hussain A, Rizwan ul Haq M, Al Ayedh H, Aljabr A. Toxicity and Detoxification Mechanism of Black Pepper and Its Major Constituent in Controlling Rhynchophorus ferrugineus Olivier (Curculionidae: Coleoptera). Neotrop Entomol. 2017;46:685-693 pubmed publisher
    ..indices evaluated by calculating the efficiency of the conversion of ingested food (ECI) and digested food (ECD) at the same dose (219.88 mg/l) showed that there was maximum reduction in the ECI (49.90%) and ECD (62...
  74. Sun S, Ma K, Tao Q, Han J, Bao L, Liu L, et al. Diketopiperazines and 2H-pyran-2-ones with antioxidant activity from the rice fermented with Aspergillus luchuensis. Fitoterapia. 2018;125:266-272 pubmed publisher
    ..The structures of 1-5 were determined by extensive spectral analysis including 1D and 2D NMR, HRESIMS, and CD, and ECD calculation...
  75. Kim J, Kim B, Hwang S, Chang W, Kim K, Kwon H, et al. Symptom-associated change of motor-related neuromagnetic fields in a patient with multiple sclerosis: A case report. J Clin Neurosci. 2018;50:115-122 pubmed publisher
    ..The Equivalent current dipole (ECD) strength of the movement-evoked field (MEF) in the affected hemisphere was significantly decreased relative to the ..
  76. Du Y, Abedi A, Valenciano A, Fernández Murga M, Cassera M, Rasamison V, et al. Isolation of the New Antiplasmodial Butanolide, Malleastrumolide A, from Malleastrum sp. (Meliaceae) from Madagascar. Chem Biodivers. 2017;: pubmed publisher
    ..The structure of malleastrumolide A was determined by mass spectrometry, NMR, and ECD. The double bond position was determined by cross-metathesis and mass spectrometry...
  77. Lou L, Yao G, Wang J, Zhao W, Wang X, Huang X, et al. Enantiomeric neolignans from Picrasma quassioides exhibit distinctive cytotoxicity on hepatic carcinoma cells through ROS generation and apoptosis induction. Bioorg Med Chem Lett. 2018;28:1263-1268 pubmed publisher
    ..Their structures were established by comprehensive spectroscopic analyses as well as ECD spectroscopy...
  78. Diamond E, Subbiah V, Lockhart A, Blay J, Puzanov I, Chau I, et al. Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Analysis of Data From the Histology-Independent, Phase 2, Open-label VE-BASKET Study. JAMA Oncol. 2017;: pubmed publisher
    The histiocytic neoplasms Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) are highly enriched for BRAF V600 mutations and have been previously shown to be responsive to treatment with vemurafenib, an inhibitor of ..
  79. Zhang G, Hu F, Jiang H, Dai L, Liao H, Li N, et al. Mappianines A-E, structurally diverse monoterpenoid indole alkaloids from Mappianthus iodoides. Phytochemistry. 2018;145:68-76 pubmed publisher
    ..and absolute configurations were determined by spectroscopic analysis, single-crystal X-ray diffraction, and ECD calculations. The plausible biogenetic pathway of mappianine A was proposed...
  80. Yang J, Zhang B, Gao T, Yang M, Zhao G, Zhu H, et al. A pair of enantiomeric 5-oxabicyclic[4.3.0]lactam derivatives and one new polyketide from the marine-derived fungus Penicillium griseofulvum. Nat Prod Res. 2017;:1-4 pubmed publisher
    ..and absolute configurations were elucidated through extensive spectroscopic analyses combined with the calculated ECD spectra. Penicitrinone F (2) had moderate inhibitory activity towards Bacillus subtilis with a MIC value of 6.3 ?M.
  81. Pan X, He J, Wang X, Zhang J, Ma B, Zhang W, et al. An unusual racemic C12-norabietane diterpene and a new abietane diterpene alkaloid from Salvia miltiorrhiza Bunge. Fitoterapia. 2018;125:240-244 pubmed publisher
    ..The absolute configurations of 1a [(+)-miltiorolide A], 1b [(-)-miltiorolide A], and 2 were determined using TDDFT-ECD calculations...
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    ..application of ecdysone, and nerve terminal structure for differences between the reduced ecdysone genotype, ecd(1)/ecd(1), and wild-type control ecd(1)/TM6B animals during the early and late third instars when raised at 25 ..
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    ..possible effect of intraocular inflammation on corneal endothelium by describing corneal endothelial cell density (ECD) and morphologic variables in eyes with anterior uveitis, and to investigate factors that may influence these ..
  85. Tan A, Yzer S, Atebara N, Marr B, Verdijk R, Dalm V, et al. Three Cases of Erdheim-Chester Disease With Intraocular Manifestations: Imaging and Histopathology Findings of a Rare Entity. Am J Ophthalmol. 2017;176:141-147 pubmed publisher
    To report intraocular manifestations of Erdheim-Chester Disease (ECD) with multimodal imaging. A retrospective observational case series...
  86. Pan Z, Kleinschmidt Demasters B. CNS Erdheim-Chester Disease: A Challenge to Diagnose. J Neuropathol Exp Neurol. 2017;76:986-996 pubmed publisher
    Erdheim-Chester disease (ECD) is a rare nonLangerhans cell histiocytosis. Although approximately 50% of cases eventually involve the central nervous system (CNS), the CNS has seldom been reported as the initial biopsy site...
  87. Maeda S, Kameda Y, Amo Y, Usuki T, Ikeda K, Otomo T, et al. Local Structure of Li+ in Concentrated Ethylene Carbonate Solutions Studied by Low-Frequency Raman Scattering and Neutron Diffraction with 6Li/7Li Isotopic Substitution Methods. J Phys Chem B. 2017;: pubmed publisher
    ..cross sections observed for 6Li/7Li isotopically substituted 10 and 25 mol % *LiTFSA-ECd4 solutions...
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    The DSS1 protein interacts with the breast cancer susceptibility protein BRCA2 that plays an integral role in the repair of DNA double-strand breaks (DSBs)...
  89. Njock G, Grougnet R, Efstathiou A, Smirlis D, Genta Jouve G, Michel S, et al. A Nitrile Glucoside and Biflavones from the Leaves of Campylospermum excavatum (Ochnaceae). Chem Biodivers. 2017;14: pubmed publisher
    ..absolute configurations were assigned by 1D- and 2D-NMR experiments, HR-ESI-MS and Electronic Circular Dichroism (ECD) calculations...
  90. Lanata A, Guidi A, Greco A, Valenza G, Scilingo E. Monitoring voluntary blink magnitude through a wearable eye-tracking system: A preliminary study. Conf Proc IEEE Eng Med Biol Soc. 2017;2017:1583-1586 pubmed publisher
    ..e. Integrated Gaze Path (IGP) and Eye-closed Duration (ECD), IGP reported a higher Spearman's correlation values with eye-blink reflex magnitude (EBM) than ECD...
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    Vibrational and electronic circular dichroism (VCD and ECD) spectra of 3 optically active bilirubin analogs with propionic acid groups replaced by (1) 1-(S)-methylpropyl groups, (2) 3-acetoxy-1-(S)-methylpropyl groups, and (3) 1-(S)-2-(R)..
  92. Michalska K, Bednarek E, Gruba E, Lewandowska K, Mizera M, Cielecka Piontek J. Comprehensive spectral identification of key intermediates to the final product of the chiral pool synthesis of radezolid. Chem Cent J. 2017;11:82 pubmed publisher
    ..studied using infrared radiation (FT-IR), Raman scattering (3, 5, 9), and electronic circular dichroism (ECD) (5, 12) spectroscopy. Each technique provides a unique and specific set of information...