SARS2

Summary

Gene Symbol: SARS2
Description: seryl-tRNA synthetase 2, mitochondrial
Alias: SARS, SARSM, SERS, SYS, SerRS, SerRSmt, mtSerRS, serine--tRNA ligase, mitochondrial, mitochondrial seryl-tRNA synthetase, serine tRNA ligase 2, mitochondrial, seryl-tRNA synthetase, mitochondrial, seryl-tRNA(Ser/Sec) synthetase
Species: human
Products:     SARS2

Top Publications

  1. Magrini A, Grana M, Vicentini L. [Chemical, physical and biological risks in law enforcement]. G Ital Med Lav Ergon. 2014;36:382-91 pubmed
    ..biological risks are blood-borne diseases (viral hepatitis, AIDS), airborne diseases (eg, tuberculosis, meningitis, SARS, anthrax), MRSA, and vector-borne diseases...
  2. Bayrakdar F, Altas A, Korukluoglu G, Topal S. [Molecular diagnosis and phylogenetic analysis of the first MERS case in Turkey]. Mikrobiyol Bul. 2015;49:414-22 pubmed
    ..Until recently five types of human coronaviruses (HCoV-OC43, HCoV-HKU1, HCoV-NL63, HCoV-229E, SARS-CoV) have been known, however a novel CoV has been identified in 2012 in Saudi Arabia...
  3. Warnes S, Little Z, Keevil C. Human Coronavirus 229E Remains Infectious on Common Touch Surface Materials. MBio. 2015;6:e01697-15 pubmed publisher
    ..to environmental stresses, but the human coronaviruses responsible for severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) have recently caused increasing concern of contact transmission during ..
  4. Case J, Ashbrook A, Dermody T, Denison M. Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity. J Virol. 2016;90:7248-7256 pubmed publisher
    ..Human coronaviruses, most notably severe acute respiratory syndrome (SARS)-CoV and Middle East respiratory syndrome (MERS)-CoV, cause severe and lethal human disease...
  5. Minakshi R, Padhan K, Rehman S, Hassan M, Ahmad F. The SARS Coronavirus 3a protein binds calcium in its cytoplasmic domain. Virus Res. 2014;191:180-3 pubmed publisher
    The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is a positive stranded RNA virus with ∼30kb genome...
  6. Wang Y, Liu L. The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism. MBio. 2016;7:e01872-15 pubmed publisher
    ..In this study, we demonstrate that delivering the membrane gene of severe acute respiratory syndrome coronavirus (SARS-CoV) into HEK293T, HEK293ET, and immobilized murine bone marrow-derived macrophage (J2-Mφ) cells significantly ..
  7. Dai W, White R, Liu J, Liu H. Seryl-tRNA synthetase-mediated essential amino acids regulate β-casein synthesis via cell proliferation and mammalian target of rapamycin (mTOR) signaling pathway in bovine mammary epithelial cells. J Dairy Sci. 2018;101:10456-10468 pubmed publisher
    ..This study examined the effects of seryl-tRNA synthetase (SARS) on EAA-stimulated β-casein synthesis, cell proliferation, and the mammalian target of rapamycin (mTOR) system in ..
  8. Lin C, Lee M, Lin J, Lin M, Chueh F, Yu C, et al. Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells. Environ Toxicol. 2016;31:957-69 pubmed publisher
    ..CERP) has been used for treating different diseases, including SARS, rheumatoid arthritis, coxsackievirus B3, and human colon cancer cell, pancreatic cancer...
  9. Deng X, StJohn S, Osswald H, O Brien A, Banach B, Sleeman K, et al. Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance. J Virol. 2014;88:11886-98 pubmed publisher
    ..blocking the replication of coronavirus (CoV), including the causative agents of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), provide a promising foundation for the development of anticoronaviral ..

More Information

Publications155 found, 100 shown here

  1. Bleau C, Filliol A, Samson M, Lamontagne L. Brain Invasion by Mouse Hepatitis Virus Depends on Impairment of Tight Junctions and Beta Interferon Production in Brain Microvascular Endothelial Cells. J Virol. 2015;89:9896-908 pubmed publisher
    ..Indeed, the severe acute respiratory syndrome coronavirus (SARS-CoV), causing severe acute respiratory syndrome, and the CoVs OC43 and 229E were found in the brains of SARS ..
  2. Ou X, Zheng W, Shan Y, Mu Z, Dominguez S, Holmes K, et al. Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins. J Virol. 2016;90:5586-5600 pubmed publisher
    ..We also selectively mutated residues in pFPs of two other β-CoVs, severe acute respiratory syndrome coronavirus (SARS-CoV) and mouse hepatitis virus (MHV)...
  3. Eggers M, Koburger Janssen T, Eickmann M, Zorn J. In Vitro Bactericidal and Virucidal Efficacy of Povidone-Iodine Gargle/Mouthwash Against Respiratory and Oral Tract Pathogens. Infect Dis Ther. 2018;7:249-259 pubmed publisher
    ..test EN13727 and against severe acute respiratory syndrome and Middle East respiratory syndrome coronaviruses (SARS-CoV and MERS-CoV), rotavirus strain Wa and influenza virus A subtype H1N1 according to virucidal quantitative ..
  4. Stewart H, Brown K, Dinan A, Irigoyen N, Snijder E, Firth A. Transcriptional and Translational Landscape of Equine Torovirus. J Virol. 2018;92: pubmed publisher
    ..These viruses are related to important human pathogens, including severe acute respiratory syndrome (SARS) coronavirus, and they share some common features; however, the mechanism that they use to produce sgRNA molecules ..
  5. Hsu S. Compounds Derived from Epigallocatechin-3-Gallate (EGCG) as a Novel Approach to the Prevention of Viral Infections. Inflamm Allergy Drug Targets. 2015;14:13-8 pubmed
    ..Outbreaks of emerging lethal viruses, such as Ebola virus, severe acute respiratory syndrome (SARS) virus and Middle East respiratory syndrome (MERS) virus, could lead to epidemics or even pandemics if they are not ..
  6. Irigoyen N, Firth A, Jones J, Chung B, Siddell S, Brierley I. High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling. PLoS Pathog. 2016;12:e1005473 pubmed publisher
    ..Several coronaviruses, such as Severe acute respiratory syndrome-related coronavirus (SARS-CoV) and Middle East respiratory syndrome-related coronavirus (MERS-CoV), are of medical importance, with high ..
  7. Pauly M, Pir J, Loesch C, Sausy A, Snoeck C, Hübschen J, et al. Novel Alphacoronaviruses and Paramyxoviruses Cocirculate with Type 1 and Severe Acute Respiratory System (SARS)-Related Betacoronaviruses in Synanthropic Bats of Luxembourg. Appl Environ Microbiol. 2017;83: pubmed publisher
    ..strains were identified in different Myotis emarginatus colonies, and severe acute respiratory syndrome (SARS)-related Betacoronavirus strains were shed by Rhinolophus ferrumequinum Logistic regression revealed ..
  8. Shirato K, Kanou K, Kawase M, Matsuyama S. Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry. J Virol. 2017;91: pubmed
    ..Therefore, therapeutic agents for coronavirus-mediated diseases, such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), should target cell surface TMPRSS2 rather than endosomal cathepsin.
  9. Goldstein S, Thornbrough J, Zhang R, Jha B, Li Y, Elliott R, et al. Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L. J Virol. 2017;91: pubmed publisher
    ..animal pathogens, including the recently emerged viruses severe acute respiratory syndrome-associated coronavirus (SARS-CoV) and Middle East respiratory syndrome-associated coronavirus (MERS-CoV)...
  10. Phillips J, Gallagher T, Weiss S. Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion. J Virol. 2017;91: pubmed publisher
    ..includes viruses that cause two emerging diseases of humans, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), as well as a number of important animal pathogens...
  11. Rodhain F. [Bats and Viruses: complex relationships]. Bull Soc Pathol Exot. 2015;108:272-89 pubmed publisher
    ..Family Rhabdoviridae), Nipah and Hendra viruses (Paramyxoviridae), Ebola and Marburg viruses (Filoviridae), SARS-CoV and MERS-CoV (Coronaviridae)...
  12. Mackay I, Arden K. MERS coronavirus: diagnostics, epidemiology and transmission. Virol J. 2015;12:222 pubmed publisher
    ..Compared to severe acute respiratory syndrome (SARS), another sometimes- fatal zoonotic coronavirus disease that has since disappeared, MERS progresses more rapidly to ..
  13. Zhang M, Li X, Deng Z, Chen Z, Liu Y, Gao Y, et al. Structural Biology of the Arterivirus nsp11 Endoribonucleases. J Virol. 2017;91: pubmed
    ..and conserved in the arterivirus, but they are greatly different from that of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses (CoV), representing important human pathogens in the ..
  14. Chen J, Wu D, Li T, Yang K, Cheng L, Zhou Z, et al. Arylurea Derivatives: A Class of Potential Cancer Targeting Agents. Curr Top Med Chem. 2017;17:3099-3130 pubmed publisher
    ..This review focuses on the Structure-Activity Relationships (SARs) of these arylureas...
  15. Zhang R, Li Y, Cowley T, Steinbrenner A, Phillips J, Yount B, et al. The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU. J Virol. 2015;89:3598-609 pubmed publisher
    ..The spread of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) into human populations demonstrates the zoonotic ..
  16. Zhou Y, Vedantham P, Lu K, Agudelo J, Carrion R, Nunneley J, et al. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015;116:76-84 pubmed publisher
    In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases...
  17. Maringer K, Fernandez Sesma A. Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection. Cytokine Growth Factor Rev. 2014;25:669-79 pubmed publisher
    ..Finally, we discuss STING antagonism in the coronaviruses SARS coronavirus and human coronavirus NL63, which disrupt K63-linked polyubiquitination and dimerisation of STING (both ..
  18. Wang Y, Sun Y, Wu A, Xu S, Pan R, Zeng C, et al. Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis. J Virol. 2015;89:8416-27 pubmed publisher
    ..Previous studies showed that the 2'-O-MTase activity of severe acute respiratory syndrome coronavirus (SARS-CoV) nonstructural protein 16 (nsp16) needs to be activated by nsp10, whereas nsp16 of feline coronavirus (FCoV) ..
  19. He B, Huang X, Zhang F, Tan W, Matthijnssens J, Qin S, et al. Group A Rotaviruses in Chinese Bats: Genetic Composition, Serology, and Evidence for Bat-to-Human Transmission and Reassortment. J Virol. 2017;91: pubmed publisher
    ..b>IMPORTANCE Bat viruses, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), Ebola, Hendra, and Nipah viruses, are important pathogens causing ..
  20. Wong H, Kumar P, Tay F, Moreau D, Liu D, Bard F. Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes. J Virol. 2015;89:11116-28 pubmed publisher
    ..host switching, representing a real threat for public health, as evidenced by severe acute respiratory syndrome (SARS) and the emerging Middle East respiratory syndrome (MERS)...
  21. Vijay R, Hua X, Meyerholz D, Miki Y, Yamamoto K, Gelb M, et al. Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection. J Exp Med. 2015;212:1851-68 pubmed publisher
    ..properties, contributed to worse outcomes in mice infected with severe acute respiratory syndrome-coronavirus (SARS-CoV)...
  22. Ma Y, Wu L, Shaw N, Gao Y, Wang J, Sun Y, et al. Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex. Proc Natl Acad Sci U S A. 2015;112:9436-41 pubmed publisher
    ..Here, we describe crystal structures of severe acute respiratory syndrome (SARS)-CoV nsp14 in complex with its activator nonstructural protein10 (nsp10) and functional ligands...
  23. Oudshoorn D, Rijs K, Limpens R, Groen K, Koster A, Snijder E, et al. Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication. MBio. 2017;8: pubmed publisher
    ..suggested that the nonstructural proteins (nsp's) 3, 4, and 6 of the severe acute respiratory syndrome coronavirus (SARS-CoV), which contain transmembrane domains, would all be required for DMV formation...
  24. Pope W, Jacobs Sera D, Russell D, Rubin D, Kajee A, Msibi Z, et al. Genomics and proteomics of mycobacteriophage patience, an accidental tourist in the Mycobacterium neighborhood. MBio. 2014;5:e02145 pubmed publisher
    Newly emerging human viruses such as Ebola virus, severe acute respiratory syndrome (SARS) virus, and HIV likely originate within an extant population of viruses in nonhuman hosts and acquire the ability to infect and cause disease in ..
  25. Huys R. Harpacticoid copepods-their symbiotic associations and biogenic substrata: a review. Zootaxa. 2016;4174:448-729 pubmed publisher
    ..The genus Idomenella T. Scott, 1906a (Pseudotachidiidae), previously a junior subjective synonym of Dactylopodella Sars, 1905a, is reinstated to accommodate Dactylopodella rostrata (T. Scott, 1893), D...
  26. Sato K, Misawa N, Takeuchi J, Kobayashi T, Izumi T, Aso H, et al. Experimental Adaptive Evolution of Simian Immunodeficiency Virus SIVcpz to Pandemic Human Immunodeficiency Virus Type 1 by Using a Humanized Mouse Model. J Virol. 2018;92: pubmed publisher
    ..We further demonstrate a gain-of-function evolution of SIVcpz in infected humanized mice. Our study reveals that pandemic HIV-1 has emerged through at least two steps: preadaptation and subsequent gain-of-function mutations. ..
  27. Mahapatra D, Bharti S, Asati V. Anti-cancer chalcones: Structural and molecular target perspectives. Eur J Med Chem. 2015;98:69-114 pubmed publisher
    ..targets/pathways involved in carcinogenesis, mechanism of actions (MOAs), structure activity relationships (SARs) and patents granted have been highlighted...
  28. Shin K, Choi J, Cho J, Yoon M, Lee S, Chung H. Feasibility of asymmetrical flow field-flow fractionation as a method for detecting protective antigen by direct recognition of size-increased target-captured nanoprobes. J Chromatogr A. 2015;1422:239-246 pubmed publisher
    ..In parallel, the feasibility of surface-enhanced Raman scattering (SERS) as a potential AF4 detection method was also evaluated...
  29. Squarcialupi L, Falsini M, Catarzi D, Varano F, Betti M, Varani K, et al. Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors. Bioorg Med Chem. 2016;24:2794-808 pubmed publisher
    ..Molecular docking investigations performed at the hA2A AR crystal structure and at a homology model of the hA1 AR allowed us to represent the hypothetical binding mode of our derivatives and to rationalize the observed SARs.
  30. Farkhari N, Abbasian S, Moshaii A, Nikkhah M. Mechanism of adsorption of single and double stranded DNA on gold and silver nanoparticles: Investigating some important parameters in bio-sensing applications. Colloids Surf B Biointerfaces. 2016;148:657-664 pubmed publisher
    ..From surface enhanced Raman spectroscopy (SERS) data of various bases in the presence of gold nanoparticles, the probable interaction points in the bases with the ..
  31. Wei W, Huang Q. Preparation of cellophane-based substrate and its SERS performance on the detection of CV and acetamiprid. Spectrochim Acta A Mol Biomol Spectrosc. 2018;193:8-13 pubmed publisher
    Cellophane was taken as platform to fabricate a new SERS substrate via silver mirror action. From Raman spectra, it can be found that the Raman signal of Ag-coated cellophane has little influence on the detection of analytes molecules...
  32. Fu L, Zhu D, Yu A. Galvanic replacement synthesis of silver dendrites-reduced graphene oxide composites and their surface-enhanced Raman scattering characteristics. Spectrochim Acta A Mol Biomol Spectrosc. 2015;149:396-401 pubmed publisher
    ..The surface-enhanced Raman scattering (SERS) property of the as synthesized AgD/RGO composite was evaluated using Rhodamine B as a probe...
  33. Nittner Marszalska M, Liebhart J, Dor Wojnarowska A. Sex-related clinical aspects in insect venom anaphylaxis. Int J Immunopathol Pharmacol. 2015;28:187-93 pubmed publisher
    ..In the majority of recent studies the frequency of HVA symptoms with respect to both LL and SYS reactions is similar for men and women, while proven sensitization to insect venom is less frequent in women...
  34. Lai Y, Hou C, Yun C, Sung K, Su C, Wu T, et al. The association among MDCT-derived three-dimensional visceral adiposities on cardiac diastology and dyssynchrony in asymptomatic population. BMC Cardiovasc Disord. 2015;15:142 pubmed publisher
    ..Intra-ventricular systolic (Sys-D) and diastolic (Dias-D) dyssynchrony were assessed by TDI method...
  35. Mo A, Landon P, Gomez K, Kang H, Lee J, Zhang C, et al. Magnetically-responsive silica-gold nanobowls for targeted delivery and SERS-based sensing. Nanoscale. 2016;8:11840-50 pubmed publisher
    ..These magnetically-responsive nanobowls show distinct surface enhanced Raman spectroscopy (SERS) imaging capability. The PEGylated magnetically-responsive nanobowls show size-dependent cellular uptake in vitro.
  36. Bailey M, Schultz Z. SERS speciation of the electrochemical oxidation-reduction of riboflavin. Analyst. 2016;141:5078-87 pubmed publisher
    ..By performing surface-enhanced Raman scattering (SERS) with simultaneous electrochemical detection of riboflavin at different pH values, we are able to correlate ..
  37. Hermann T. Small molecules targeting viral RNA. Wiley Interdiscip Rev RNA. 2016;7:726-743 pubmed publisher
    ..inhibitors of human immunodeficiency virus (HIV), hepatitis C virus (HCV), severe respiratory syndrome coronavirus (SARS CoV), and influenza A virus...
  38. Peduto A, Scuotto M, Krauth V, Roviezzo F, Rossi A, Temml V, et al. Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase. Eur J Med Chem. 2017;127:715-726 pubmed publisher
    ..modify the structures and thus to improve the inhibitory potential in vitro and in vivo as well as to investigate SARs. Systematic structural optimization through accurate structure-based design resulted in compound 30 (3-tridecyl-4,5-..
  39. Hui D. Epidemic and Emerging Coronaviruses (Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome). Clin Chest Med. 2017;38:71-86 pubmed publisher
    Bats are the natural reservoirs of severe acute respiratory syndrome (SARS)-like coronaviruses (CoVs) and likely the reservoir of Middle East respiratory syndrome (MERS)-CoV...
  40. Singh G, Bi R, Dinish U, Olivo M. Generating Localized Plasmonic Fields on an Integrated Photonic Platform using Tapered Couplers for Biosensing Applications. Sci Rep. 2017;7:15587 pubmed publisher
    ..plasmonic structure for highly sensitive biosensing applications using surface enhanced Raman scattering (SERS) and metal enhanced fluorescence (MEF) techniques is discussed...
  41. Chen M, Luo W, Zhang Z, Wang R, Zhu Y, Yang H, et al. Synthesis of Multi-Au-Nanoparticle-Embedded Mesoporous Silica Microspheres as Self-Filtering and Reusable Substrates for SERS Detection. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    Surface-enhanced Raman-scattering-based (SERS-based) biosensing in biological fluids is constrained by nonspecific macromolecule adsorptions and disposable property of the SERS substrate...
  42. Vereecken L, Novelli A, Taraborrelli D. Unimolecular decay strongly limits the atmospheric impact of Criegee intermediates. Phys Chem Chem Phys. 2017;19:31599-31612 pubmed publisher
    ..is strongly limited by their unimolecular decay, based on extensive theory-based structure-activity relationships (SARs) for the reaction rates for decomposition...
  43. Mackay I, Arden K. An Opportunistic Pathogen Afforded Ample Opportunities: Middle East Respiratory Syndrome Coronavirus. Viruses. 2017;9: pubmed publisher
    ..The severe acute respiratory syndrome (SARS) CoV briefly emerged into the human population but was controlled...
  44. Mahapatra D, Bharti S, Asati V. Chalcone scaffolds as anti-infective agents: structural and molecular target perspectives. Eur J Med Chem. 2015;101:496-524 pubmed publisher
    ..features of anti-infective chalcones, their mechanism of actions (MOAs) and structure activity relationships (SARs) have been highlighted...
  45. Berry M, Fielding B, Gamieldien J. Potential Broad Spectrum Inhibitors of the Coronavirus 3CLpro: A Virtual Screening and Structure-Based Drug Design Study. Viruses. 2015;7:6642-60 pubmed publisher
    ..The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory syndrome (MERS) less than 10 years later demonstrates the potential of ..
  46. Lu T, Lee Y, Yen Y, Yu C, Chen H. Astronomical liquid mirrors as highly ultrasensitive, broadband-operational surface-enhanced Raman scattering-active substrates. J Colloid Interface Sci. 2016;466:80-90 pubmed publisher
    ..as a highly ultrasensitive, low-cost, highly reproducible, broadband-operational surface-enhanced Raman scattering (SERS)-active substrate...
  47. Chen C, Lee C, Liu F, Chen T, Ahmed Ali A, Chang D, et al. Design, synthesis and SARs of novel salicylanilides as potent inhibitors of RANKL-induced osteoclastogenesis and bone resorption. Eur J Med Chem. 2016;117:70-84 pubmed publisher
    ..Accordingly, we present the potent anti-osteoclastogenic compounds A04 and B04 as promising candidates for further optimization as anti-resorptive agents. ..
  48. Zheng J, Zhao C, Tian G, He L. Rapid screening for ricin toxin on letter papers using surface enhanced Raman spectroscopy. Talanta. 2017;162:552-557 pubmed publisher
    ..Three sample preparation methods and two SERS substrates were evaluated and optimized for their performance on three types of letter papers...
  49. Crawford R, Rutz D, Evans D. 'Between Combat boots and Birkenstocks'-Lessons from HIV/AIDS, SARS, H1N1 and Ebola. Public Health. 2016;141:186-191 pubmed publisher
    ..HIV/AIDS, SARS and H1N1 tested global response, and in each case coordination proved problematic, making the 2013-2015 Ebola ..
  50. Geng P, Wang C, Li Z, Hu X, Zhao T, Fu D, et al. Design, synthesis and preliminary biological evaluation of 5,8-dihydropteridine-6,7-diones that induce apoptosis and suppress cell migration. Eur J Med Chem. 2018;143:1959-1967 pubmed publisher
    ..The SARs studies highlighted the importance of the piperazine substituted 5,8-dihydropteridine-6,7-dione frameworks for the ..
  51. Dhakal S, Chao K, Huang Q, Kim M, Schmidt W, Qin J, et al. A Simple Surface-Enhanced Raman Spectroscopic Method for on-Site Screening of Tetracycline Residue in Whole Milk. Sensors (Basel). 2018;18: pubmed publisher
    ..This study developed a simple surface-enhanced Raman spectroscopic (SERS) method for on-site screening of tetracycline residue in milk and water...
  52. Morlière C, Verpillot E, Donon L, Salmi L, Joseph P, Vignes J, et al. A cost-utility analysis of sacral anterior root stimulation (SARS) compared with medical treatment in patients with complete spinal cord injury with a neurogenic bladder. Spine J. 2015;15:2472-83 pubmed publisher
    Sacral anterior root stimulation (SARS) and posterior sacral rhizotomy restores the ability to urinate on demand with low residual volumes, which is a key for preventing urinary complications that account for 10% of the causes of death in ..
  53. Hardiansyah A, Chen A, Liao H, Yang M, Liu T, Chan T, et al. Core-shell of FePt@SiO2-Au magnetic nanoparticles for rapid SERS detection. Nanoscale Res Lett. 2015;10:412 pubmed publisher
    ..FePt), silica (SiO2), and gold nanoparticles (AuNPs) had been developed for surface-enhanced Raman scattering (SERS) application...
  54. Yang D, Zhou H, Haisch C, Niessner R, Ying Y. Reproducible E. coli detection based on label-free SERS and mapping. Talanta. 2016;146:457-63 pubmed publisher
    The biosensing for rapid detection of bacteria based on surface-enhanced Raman scattering (SERS) has been widely explored for recent years...
  55. Tay A, Pavesi A, Yazdi S, Lim C, Warkiani M. Advances in microfluidics in combating infectious diseases. Biotechnol Adv. 2016;34:404-421 pubmed publisher
    ..Other infectious diseases such as SARS, tuberculosis, and dengue are also briefly discussed...
  56. Kahan T, Claudatos S. Phenomenological features of dreams: Results from dream log studies using the Subjective Experiences Rating Scale (SERS). Conscious Cogn. 2016;41:159-76 pubmed publisher
    ..experiences were obtained from 144 college women for 788 dreams, using the Subjective Experiences Rating Scale (SERS)...
  57. Kamel E, Mahmoud A, Ahmed S, Lamsabhi A. A phytochemical and computational study on flavonoids isolated from Trifolium resupinatum L. and their novel hepatoprotective activity. Food Funct. 2016;7:2094-106 pubmed publisher
    ..Therefore, the present study provides the first clarification of the detailed antioxidant SARs of T. resupinatum flavonoids and points to the involvement of Nrf2 in their hepatoprotective activity.
  58. Phan Quang G, Lee H, Ling X. Isolating Reactions at the Picoliter Scale: Parallel Control of Reaction Kinetics at the Liquid-Liquid Interface. Angew Chem Int Ed Engl. 2016;55:8304-8 pubmed publisher
    ..Using the surface-enhanced Raman spectroscopy (SERS) technique, in?situ monitoring of the interfacial protonation of dimethyl yellow (p-dimethylaminoazobenzene (DY)) ..
  59. Fordham D, Brook B, Hoskin C, Pressey R, VanDerWal J, Williams S. Extinction debt from climate change for frogs in the wet tropics. Biol Lett. 2016;12: pubmed
    ..Furthermore, we find congruence between forecast rates of extinction using SARs, and demographic models with an extinction lag of 120 years...
  60. Wang P, Pang S, Pearson B, Chujo Y, McLandsborough L, Fan M, et al. Rapid concentration detection and differentiation of bacteria in skimmed milk using surface enhanced Raman scattering mapping on 4-mercaptophenylboronic acid functionalized silver dendrites. Anal Bioanal Chem. 2017;409:2229-2238 pubmed publisher
    ..to rapidly concentrate, detect, and differentiate bacteria in skimmed milk using surface enhanced Raman scattering (SERS) mapping on 4-mercaptophenylboronic acid (4-MPBA) functionalized silver (Ag) dendrites...
  61. Iyengar P, von Mollendorf C, Tempia S, Moerdyk A, Valley Omar Z, Hellferscee O, et al. Case-ascertained study of household transmission of seasonal influenza - South Africa, 2013. J Infect. 2015;71:578-86 pubmed publisher
    ..SAR for laboratory-confirmed influenza in South Africa was higher than previously reported SARs. Household contacts did not report changing behaviors to prevent transmission...
  62. Sun C, Chen C, Xu S, Wang J, Zhu Y, Kong D, et al. Synthesis and anticancer activity of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives bearing chromone moiety. Bioorg Med Chem. 2016;24:3862-9 pubmed publisher
    ..1?M, 0.92?M and 8.77-14.3?M. Structure-activity relationships (SARs) and docking studies indicated that the thiopyrano[4,3-d]pyrimidine scaffolds exerted little effect on antitumor ..
  63. Furfaro G, Picton B, Martynov A, Mariottini P. <i>Diaphorodoris</i> <i>alba</i> Portmann &amp; Sandmeier, 1960 is a valid species: molecular and morphological comparison with <i>D. luteocincta</i> (M. Sars, 1870) (Gastropoda: Nudibranchia). Zootaxa. 2016;4193:zootaxa.4193.2.6 pubmed publisher
    The nudibranch Diaphorodoris luteocincta (M. Sars, 1870) shows two colour morphotypes defined as D. luteocincta var. alba and D. luteocincta var...
  64. Mostowtt T, McCord B. Surface enhanced Raman spectroscopy (SERS) as a method for the toxicological analysis of synthetic cannabinoids. Talanta. 2017;164:396-402 pubmed publisher
    ..A potential solution to this problem is surface enhanced Raman spectroscopy (SERS). In this study we demonstrate the analysis of a set of structurally similar synthetic cannabinoids using SERS...
  65. Bibikova O, Haas J, López Lorente A, Popov A, Kinnunen M, Meglinski I, et al. Towards enhanced optical sensor performance: SEIRA and SERS with plasmonic nanostars. Analyst. 2017;142:951-958 pubmed publisher
    ..gold nanostars at silicon substrates that enable concomitantly enhanced Raman (surface enhanced Raman spectroscopy; SERS) and mid-infrared (surface enhanced infrared reflection or absorption spectroscopy; SEIRA) spectral signatures...
  66. Sun D, Qi G, Cao F, Xu W, Chen Q, Xu S. A recyclable silver ions-specific surface-enhanced Raman scattering (SERS) sensor. Talanta. 2017;171:159-165 pubmed publisher
    A highly sensitive and recyclable surface-enhanced Raman scattering (SERS) chip sensor is designed for the determination of silver ions. It is based on the specific reversible binding between silver ions and glucose oxidase (GOD)...
  67. Guicheteau J, Tripathi A, Emmons E, Christesen S, Fountain A. Reassessing SERS enhancement factors: using thermodynamics to drive substrate design. Faraday Discuss. 2017;: pubmed publisher
    Over the past 40 years fundamental and application research into Surface-Enhanced Raman Scattering (SERS) has been explored by academia, industry, and government laboratories...
  68. Li Y, Lu R, Shen J, Han W, Sun X, Li J, et al. Electrospun flexible poly(bisphenol A carbonate) nanofibers decorated with Ag nanoparticles as effective 3D SERS substrates for trace TNT detection. Analyst. 2017;142:4756-4764 pubmed publisher
    A flexible 3D hybrid PC/Ag surface-enhanced Raman scattering (SERS) substrate was fabricated through the combination of electrospinning and in situ chemical reduction...
  69. Li D, Duan H, Wang Y, Zhang Q, Cao H, Deng W, et al. On-site preconcentration of pesticide residues in a drop of seawater by using electrokinetic trapping, and their determination by surface-enhanced Raman scattering. Mikrochim Acta. 2017;185:10 pubmed publisher
    ..electrode (RGO-SPE) and combines electrokinetic trapping (EKT) and surface-enhanced Raman scattering (SERS)...
  70. Park S, Son J, Lee T, Kim J, Han S, Park H, et al. Galvanic synthesis of three-dimensional and hollow metallic nanostructures. Nanoscale Res Lett. 2014;9:2403 pubmed publisher
    ..The 3D-NPG nanostructures were found to effectively enhance the SERS sensitivity of rhodamine 6G (R6G) molecules with a concentration up to 10(-8) M.
  71. Sotiriou G, Blattmann C, Deligiannakis Y. Nanoantioxidant-driven plasmon enhanced proton-coupled electron transfer. Nanoscale. 2016;8:796-803 pubmed publisher
    ..strong local hot-spots on the SiO2-coated Ag nanoparticles, as evidenced by surface enhanced Raman scattering (SERS)...
  72. Ma L, Huang Y, Hou M, Li J, Zhang Z. Pinhole Effect on the Melting Behavior of Ag@Al2O3 SERS Substrates. Nanoscale Res Lett. 2016;11:170 pubmed publisher
    High-temperature surface-enhanced Raman scattering (SERS) sensing is significant for practical detections, and pinhole-containing (PC) metal@oxide structures possessing both enhanced thermal stability and superior SERS sensitivity are ..
  73. Zhao J, Zhao J, Mangalam A, Channappanavar R, Fett C, Meyerholz D, et al. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity. 2016;44:1379-91 pubmed publisher
    Two zoonotic coronaviruses (CoVs)-SARS-CoV and MERS-CoV-have crossed species to cause severe human respiratory disease...
  74. Freitag I, Beleites C, Dochow S, Clement J, Krafft C, Popp J. Recognition of tumor cells by immuno-SERS-markers in a microfluidic chip at continuous flow. Analyst. 2016;141:5986-5989 pubmed
    b>SERS active nanoparticles were labeled with a reporter molecule and conjugated with anti-EpCAM antibodies...
  75. Peled R, Porath A, Wilf Miron R. Improving the quality of primary care by allocating performance-based targets, in a diverse insured population. BMC Health Serv Res. 2016;16:668 pubmed
    ..in overall performance, as well as the difference between the lowest and the highest socio-economic ranks (SERs) and Arab and non-Arab members...
  76. Nouvellet P, Cori A, Garske T, Blake I, Dorigatti I, Hinsley W, et al. A simple approach to measure transmissibility and forecast incidence. Epidemics. 2018;22:29-35 pubmed publisher
    Outbreaks of novel pathogens such as SARS, pandemic influenza and Ebola require substantial investments in reactive interventions, with consequent implementation plans sometimes revised on a weekly basis...
  77. Šubr M, Petr M, Kylián O, Stepanek J, Veis M, Procházka M. Anisotropic Optical Response of Silver Nanorod Arrays: Surface Enhanced Raman Scattering Polarization and Angular Dependences Confronted with Ellipsometric Parameters. Sci Rep. 2017;7:4293 pubmed publisher
    ..represent versatile, simple and inexpensive substrates for high sensitivity surface enhanced Raman scattering (SERS) applications...
  78. McKimm Breschkin J, Jiang S, Hui D, Beigel J, Govorkova E, Lee N. Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference. Antiviral Res. 2018;149:118-142 pubmed publisher
    ..responses and virology of respiratory infections, including influenza A(H1N1)pdm09 and A(H7N9) viruses, MERS-CoV, SARS-CoV, adenovirus Type 80, enterovirus D68, metapneumovirus and respiratory syncytial virus (RSV)...
  79. Markina N, Goryacheva I, Markin A. Sample pretreatment and SERS-based detection of ceftriaxone in urine. Anal Bioanal Chem. 2018;410:2221-2227 pubmed publisher
    ..ceftriaxone (antibiotic drug of cephalosporin class) detection in urine using surface-enhanced Raman spectroscopy (SERS). Hydroxylamine stabilized silver nanoparticles were used as SERS-active material...
  80. Liu X, Fang Q, Hu T, Ma D, Zhang X, Liu S, et al. Thickness dependent Raman spectra and interfacial interaction between Ag and epitaxial graphene on 6H-SiC(0001). Phys Chem Chem Phys. 2018;20:5964-5974 pubmed publisher
    ..The Ag particles induce the surface enhanced Raman scattering (SERS) effect and the doping effect in epitaxial graphene...
  81. Wen G, Liang X, Liu Q, Liang A, Jiang Z. A novel nanocatalytic SERS detection of trace human chorionic gonadotropin using labeled-free Vitoria blue 4R as molecular probe. Biosens Bioelectron. 2016;85:450-456 pubmed publisher
    ..with a strong resonance Rayleigh scattering (RRS) peak at 370nm and a strong surface enhanced Raman scattering (SERS) peak at 1615cm(-1) in the presence of molecular probe of Victoria blue 4R (VB4R)...
  82. Veloso A, Longo J, Muehlmann L, Tollstadius B, Souza P, Azevedo R, et al. SERS Investigation of Cancer Cells Treated with PDT: Quantification of Cell Survival and Follow-up. Sci Rep. 2017;7:7175 pubmed publisher
    In this study Surface Enhanced Raman Spectroscopy (SERS) data recorded from mouse mammary glands cancer cells (4T1 cell line) was used to assess information regarding differences between control, death and viable cells after Photodynamic ..
  83. Lin Y, Chan S, Juang Y, Hsiao H, Guh J, Liang P. Design, synthesis and cytotoxic activity of N-Modified oleanolic saponins bearing A glucosamine. Eur J Med Chem. 2018;143:1942-1958 pubmed publisher
    ..76 ?M) against HL-60 cells. Due to the interesting SARs of alkyl substitutions, we hypothesized that their location in the cell was different, and pursued a location study ..
  84. Ferhan A, Jackman J, Park J, Cho N, Kim D. Nanoplasmonic sensors for detecting circulating cancer biomarkers. Adv Drug Deliv Rev. 2018;125:48-77 pubmed publisher
    ..nanoplasmonic sensing techniques, namely surface plasmon resonance (SPR), localized surface plasmon resonance (LSPR) and surface-enhanced Raman scattering (SERS), for the detection of different classes of circulating cancer biomarkers.
  85. Ar Gouilh M, Puechmaille S, Diancourt L, Vandenbogaert M, Serra Cobo J, Lopez Roïg M, et al. SARS-CoV related Betacoronavirus and diverse Alphacoronavirus members found in western old-world. Virology. 2018;517:88-97 pubmed publisher
    The emergence of SARS-CoV and MERS-CoV, triggered the discovery of a high diversity of coronaviruses in bats...
  86. Su X, Wang Y, Wang W, Sun K, Chen L. Phospholipid Encapsulated AuNR@Ag/Au Nanosphere SERS Tags with Environmental Stimulus Responsive Signal Property. ACS Appl Mater Interfaces. 2016;8:10201-11 pubmed publisher
    Surface-enhanced Raman scattering (SERS) tags draw much attention due to the ultrasensitivity and multiplex labeling capability...
  87. Wang M, Xu S, Lei H, Wang C, Xiao Z, Jia S, et al. Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold. Bioorg Med Chem. 2017;25:5754-5763 pubmed publisher
    ..92±0.68μM, 3.44±0.50μM and 3.18±0.18μM). Structure-activity relationships (SARs) and docking studies indicated that the pyrazole scaffolds exerted key effect on antitumor activities of target ..
  88. Jiang T, Wang X, Tang S, Zhou J, Gu C, Tang J. Seed-mediated synthesis and SERS performance of graphene oxide-wrapped Ag nanomushroom. Sci Rep. 2017;7:9795 pubmed publisher
    ..Ag nanosphere@PSPAA with another Ag layer for achieving an enhancement of their surface-enhanced Raman scattering (SERS) activity...
  89. Wang Y, Sun Y, Chen D, Zhang X, Guo L, Wang R. Molecular Tilting Alignment on Ag@C Nanocubes Monitored by Temperature-Dependent Surface Enhanced Raman Scattering. Sci Rep. 2017;7:12865 pubmed publisher
    ..Considering that optical properties of nanostructured metals strongly depend on the temperature for SERS measurement, in this work we systemically investigate the relationship between the orientation of molecules ..
  90. Powell J, Venkatakrishnan K, Tan B. Toward Universal SERS Detection of Disease Signaling Bioanalytes Using 3D Self-Assembled Nonplasmonic near-Quantum-Scale Silicon Probe. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    Currently, the quantum-scale surface-enhanced Raman scattering (SERS) properties of Si materials have yet to be discovered for universal biosensing applications...
  91. Mandrile L, Giovannozzi A, Durbiano F, Martra G, Rossi A. Rapid and sensitive detection of pyrimethanil residues on pome fruits by Surface Enhanced Raman Scattering. Food Chem. 2018;244:16-24 pubmed publisher
    Surface Enhanced Raman Scattering (SERS) supported by gold nanoparticles (AuNPs) was applied to detect and quantify residues of pyrimethanil on pome fruits, a widely used fungicide in horticultural species...
  92. Menachery V, Gralinski L, Mitchell H, Dinnon K, Leist S, Yount B, et al. Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis. mSphere. 2017;2: pubmed publisher
    ..threat to global public health, as evidenced by the sudden emergence of severe acute respiratory syndrome CoV (SARS-CoV), MERS-CoV, porcine epidemic diarrhea virus, and swine delta CoV in the 21st century...