SALL1

Summary

Gene Symbol: SALL1
Description: spalt like transcription factor 1
Alias: HEL-S-89, HSAL1, Sal-1, TBS, ZNF794, sal-like protein 1, epididymis secretory protein Li 89, zinc finger protein 794, zinc finger protein SALL1, zinc finger protein Spalt-1
Species: human
Products:     SALL1

Top Publications

  1. Ma Y, Chai L, Cortez S, Stopa E, Steinhoff M, Ford D, et al. SALL1 expression in the human pituitary-adrenal/gonadal axis. J Endocrinol. 2002;173:437-48 pubmed
    b>SALL1 was originally identified on the basis of its DNA sequence homology to the region-specific homeotic gene Sal, in Drosophila melanogaster, which acts as a downstream target of hedgehog/tumor growth factor-beta-like decapentaplegic ..
  2. Chai L, Yang J, Di C, Cui W, Kawakami K, Lai R, et al. Transcriptional activation of the SALL1 by the human SIX1 homeodomain during kidney development. J Biol Chem. 2006;281:18918-26 pubmed
    b>SALL1 is a member of the SAL gene family that encodes a group of putative developmental transcription factors...
  3. Marlin S, Blanchard S, Slim R, Lacombe D, Denoyelle F, Alessandri J, et al. Townes-Brocks syndrome: detection of a SALL1 mutation hot spot and evidence for a position effect in one patient. Hum Mutat. 1999;14:377-86 pubmed
    ..The gene underlying TBS, SALL1, is a human homolog of the Drosophila spalt gene which encodes a transcription factor...
  4. Sato A, Kishida S, Tanaka T, Kikuchi A, Kodama T, Asashima M, et al. Sall1, a causative gene for Townes-Brocks syndrome, enhances the canonical Wnt signaling by localizing to heterochromatin. Biochem Biophys Res Commun. 2004;319:103-13 pubmed
    ..Mutations of human SALL1 cause the autosomal dominant disorder, Townes-Brocks syndrome (TBS), and result in ear, limb, anal, renal, and ..
  5. Netzer C, Bohlander S, Hinzke M, Chen Y, Kohlhase J. Defining the heterochromatin localization and repression domains of SALL1. Biochim Biophys Acta. 2006;1762:386-91 pubmed
    b>SALL1 has been identified as one of four human homologues of the Drosophila region-specific homeotic gene spalt (sal), encoding zinc finger proteins of characteristic structure. Mutations of SALL1 on chromosome 16q12...
  6. Sweetman D, Munsterberg A. The vertebrate spalt genes in development and disease. Dev Biol. 2006;293:285-93 pubmed
    ..Here we review what is currently known about the role of spalt genes in vertebrate development and human disease. ..
  7. Weber S, Moriniere V, Knüppel T, Charbit M, Dusek J, Ghiggeri G, et al. Prevalence of mutations in renal developmental genes in children with renal hypodysplasia: results of the ESCAPE study. J Am Soc Nephrol. 2006;17:2864-70 pubmed
    ..cysts and diabetes syndrome), PAX2 (renal-coloboma syndrome), EYA1 and SIX1 (branchio-oto-renal syndrome), and SALL1 (Townes-Brocks syndrome)...
  8. Kiefer S, Robbins L, Barina A, Zhang Z, Rauchman M. SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes. Hum Mutat. 2008;29:1133-40 pubmed publisher
    Mutations in SALL1 lead to the dominant multiorgan congenital anomalies that define Townes-Brocks syndrome (TBS)...
  9. Ramdas W, van Koolwijk L, Ikram M, Jansonius N, De Jong P, Bergen A, et al. A genome-wide association study of optic disc parameters. PLoS Genet. 2010;6:e1000978 pubmed publisher
    ..Three of the loci were marginally associated with open-angle glaucoma. The protein pathways in which the loci of optic disc area are involved overlap with those identified for VCDR, suggesting a common genetic origin. ..

More Information

Publications106 found, 100 shown here

  1. Kohlhase J, Taschner P, Burfeind P, Pasche B, Newman B, Blanck C, et al. Molecular analysis of SALL1 mutations in Townes-Brocks syndrome. Am J Hum Genet. 1999;64:435-45 pubmed
    ..Recently, we showed that mutations in the putative zinc finger transcription factor gene SALL1 cause TBS...
  2. Ma Y, Singer D, Gozman A, Ford D, Chai L, Steinhoff M, et al. Hsal 1 is related to kidney and gonad development and is expressed in Wilms tumor. Pediatr Nephrol. 2001;16:701-9 pubmed
    Townes-Brocks syndrome (TBS) is a human genetic disorder with features including urogenital, limb, anal and cardiac malformations associated with mutations of the TBS gene, Hsal 1...
  3. Al Baradie R, Yamada K, St Hilaire C, Chan W, Andrews C, McIntosh N, et al. Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family. Am J Hum Genet. 2002;71:1195-9 pubmed
    ..SALL4 represents the first identified Duane syndrome gene and the second malformation syndrome resulting from mutations in SAL genes and likely plays a critical role in abducens motoneuron development. ..
  4. Furniss D, Critchley P, Giele H, Wilkie A. Nonsense-mediated decay and the molecular pathogenesis of mutations in SALL1 and GLI3. Am J Med Genet A. 2007;143A:3150-60 pubmed
    Mutations in SALL1 and GLI3 are responsible for human limb malformation syndromes. The molecular pathophysiology of these mutations is incompletely understood, and many conclusions have been drawn from studies performed in the mouse...
  5. de Celis J, Barrio R. Regulation and function of Spalt proteins during animal development. Int J Dev Biol. 2009;53:1385-98 pubmed publisher
    ..organogenesis, and at least two human sall genes are linked to the genetic diseases Townes Brocks Syndrome (TBS; SALL1 ) and Okihiro Syndrome (OS; SALL4 )...
  6. Lu J, Jeong H, Jeong H, Kong N, Yang Y, Carroll J, et al. Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex. PLoS ONE. 2009;4:e5577 pubmed publisher
    ..The SALL4-mediated transcriptional regulation was tested on two potential target genes: PTEN and SALL1. Both genes were confirmed as SALL4 downstream targets by chromatin-immunoprecipitation, and their expression ..
  7. Kohlhase J, Wischermann A, Reichenbach H, Froster U, Engel W. Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome. Nat Genet. 1998;18:81-3 pubmed
    ..Cytogenetic findings suggested that the gene mutated in TBS maps to chromosome 16q12.1, where SALL1 (previously known as HSAL1), a human homologue of spalt (sal), is located...
  8. Engels S, Kohlhase J, McGaughran J. A SALL1 mutation causes a branchio-oto-renal syndrome-like phenotype. J Med Genet. 2000;37:458-60 pubmed
  9. Kiefer S, McDill B, Yang J, Rauchman M. Murine Sall1 represses transcription by recruiting a histone deacetylase complex. J Biol Chem. 2002;277:14869-76 pubmed
    ..In this report, we show that a member of the Sal family, mouse Sall1, is a potent transcriptional repressor...
  10. Botzenhart E, Green A, Ilyina H, König R, Lowry R, Lo I, et al. SALL1 mutation analysis in Townes-Brocks syndrome: twelve novel mutations and expansion of the phenotype. Hum Mutat. 2005;26:282 pubmed
    ..TBS has been shown to result from mutations in SALL1, a human gene related to the developmental regulator SAL of Drosophila melanogaster...
  11. Borozdin W, Steinmann K, Albrecht B, Bottani A, Devriendt K, Leipoldt M, et al. Detection of heterozygous SALL1 deletions by quantitative real time PCR proves the contribution of a SALL1 dosage effect in the pathogenesis of Townes-Brocks syndrome. Hum Mutat. 2006;27:211-2 pubmed
    ..disorder characterized by ear, anal, limb, and renal malformations, and results from mutations in the gene SALL1. All SALL1 mutations previously found in TBS patients create preterminal termination codons...
  12. Yamamoto C, Fukuda N, Matsumoto T, Higuchi T, Ueno T, Matsumoto K. Zinc-finger transcriptional factor Sall1 induces angiogenesis by activation of the gene for VEGF-A. Hypertens Res. 2010;33:143-8 pubmed publisher
    Zinc-finger transcriptional factor Sall1 modulates gene expression and regulates organogenesis, including kidney development. Angiogenesis induced by vascular endothelial growth factor (VEGF) is also required for organogenesis...
  13. Kohlhase J, Schuh R, Dowe G, Kühnlein R, Jackle H, Schroeder B, et al. Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. Genomics. 1996;38:291-8 pubmed
    ..Here we report the isolation and molecular characterization of two sal-like transcription units, termed Hsal1 and Hsal2, which are located on chromosomes 16q12.1 and 14q11.1-q12.1, respectively...
  14. Mosher M, Melton P, Stapleton P, Schanfield M, Crawford M. Patterns of DNA Methylation Across the Leptin Core Promoter in Four Diverse Asian and North American Populations. Hum Biol. 2016;88:121-135 pubmed
    ..of two of the four populations (n = 239), correlating methylation at the C/EBP? transcription binding site (TBS) with metabolic and anthropometric biomarkers reflecting LEP roles, showed that stature, which reflects bone growth ..
  15. Iki M, Fujita Y, Kouda K, Yura A, Tachiki T, Tamaki J, et al. Hyperglycemia is associated with increased bone mineral density and decreased trabecular bone score in elderly Japanese men: The Fujiwara-kyo osteoporosis risk in men (FORMEN) study. Bone. 2017;105:18-25 pubmed publisher
    ..To evaluate bone microarchitecture, trabecular bone score (TBS) was calculated at the same vertebrae as those used for aBMD measurement...
  16. Park Y, Lee G, Cheon S, Cha Y, An H. The anti-obesity effects of Tongbi-san in a high-fat diet-induced obese mouse model. BMC Complement Altern Med. 2019;19:1 pubmed publisher
    Recently, it has been noted that natural herbal medications may be effective in treating obesity. Tongbi-san (TBS) is a traditional medicine usually used for dysuria (i.e., painful urination), containing three herbs, Cyperus rotundus L...
  17. Mohanty A, Farin F, Bammler T, MacDonald J, Afsharinejad Z, Burbacher T, et al. Infant sex-specific placental cadmium and DNA methylation associations. Environ Res. 2015;138:74-81 pubmed publisher
    ..near MDS1 and EVI1 complex locus (MECOM) and one (hypermethylated) near spalt-like transcription factor 1 (SALL1), and two regions (both hypomethylated, one on chromosome 3 including MECOM and another on chromosome 8 including ..
  18. Eller Vainicher C, Bassotti A, Imeraj A, Cairoli E, Ulivieri F, Cortini F, et al. Bone involvement in adult patients affected with Ehlers-Danlos syndrome. Osteoporos Int. 2016;27:2525-31 pubmed publisher
    ..We evaluated the bone metabolism, bone mineral density (BMD) and bone quality (measured by trabecular bone score, TBS), and the prevalence of vertebral fractures (VFx) in a group of eugonadal adult EDS patients...
  19. Kremer A, Bolier R, Dixon P, Geenes V, Chambers J, Tolenaars D, et al. Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy. J Hepatol. 2015;62:897-904 pubmed publisher
    Intrahepatic cholestasis of pregnancy (ICP) is defined by pruritus, elevated total fasting serum bile salts (TBS) and transaminases, and an increased risk of adverse fetal outcome. An accurate diagnostic marker is needed...
  20. Ramirez Blanco C, Ramirez Rivero C, Díaz Martínez L, Sosa Avila L. Infection in burn patients in a referral center in Colombia. Burns. 2017;43:642-653 pubmed publisher
    ..5%), fire (10.0%), gasoline (9.2%), electricity (7.5%), among others. Burn area ranged from 1% to 80% TBS. Cumulative mortality was 1.5%. 27.8% of burned patients had one or more infections...
  21. Pérez Sáez M, Herrera S, Prieto Alhambra D, Vilaplana L, Nogues X, Vera M, et al. Bone density, microarchitecture, and material strength in chronic kidney disease patients at the time of kidney transplantation. Osteoporos Int. 2017;28:2723-2727 pubmed publisher
    ..Recently, trabecular bone score (TBS) and microindentation that can measure microarchitectural and mechanical properties of bone have demonstrated ..
  22. Carvalho A, Massaro B, Silva L, Salmon C, Fukada S, Nogueira Barbosa M, et al. Emerging Aspects of the Body Composition, Bone Marrow Adipose Tissue and Skeletal Phenotypes in Type 1 Diabetes Mellitus. J Clin Densitom. 2018;: pubmed publisher
    ..Bone mineral density (BMD) and trabecular bone score (TBS) were assessed by dual X-ray absorptiometry (DXA)...
  23. Yavropoulou M, Vaios V, Pikilidou M, Chryssogonidis I, Sachinidou M, Tournis S, et al. Bone Quality Assessment as Measured by Trabecular Bone Score in Patients With End-Stage Renal Disease on Dialysis. J Clin Densitom. 2017;20:490-497 pubmed publisher
    ..Trabecular bone score (TBS) has been recently proposed as an indirect measure of bone microarchitecture...
  24. Vlachopoulos D, Barker A, Ubago Guisado E, Fatouros I, Knapp K, Williams C, et al. Longitudinal Adaptations of Bone Mass, Geometry, and Metabolism in Adolescent Male Athletes: The PRO-BONE Study. J Bone Miner Res. 2017;32:2269-2277 pubmed publisher
    ..using hip structural analysis (HSA); and bone texture of the lumbar spine was assessed using trabecular bone score (TBS)...
  25. Kim D, Cho S, Kim J, Choi Y, Sung Y. Association between trabecular bone score and risk factors for fractures in Korean female patients with rheumatoid arthritis. Mod Rheumatol. 2016;26:540-5 pubmed publisher
    To identify the association between trabecular bone score (TBS) and other known risk factors for fractures in rheumatoid arthritis (RA) patients. One hundred female RA patients aged ≥50 years were enrolled...
  26. Martineau P, Leslie W. Trabecular bone score (TBS): Method and applications. Bone. 2017;104:66-72 pubmed publisher
    Trabecular bone score (TBS) is a texture index derived from standard lumbar spine dual energy X-ray absorptiometry (DXA) images and provides information about the underlying bone independent of the bone mineral density (BMD)...
  27. Zhukouskaya V, Eller Vainicher C, Ellen Vainicher C, Gaudio A, Privitera F, Cairoli E, et al. The utility of lumbar spine trabecular bone score and femoral neck bone mineral density for identifying asymptomatic vertebral fractures in well-compensated type 2 diabetic patients. Osteoporos Int. 2016;27:49-56 pubmed publisher
    The objective of the study was to evaluate the usefulness of trabecular bone score (TBS) and bone mineral density (BMD) for identifying vertebral fractures (VFx) in well-compensated type 2 diabetic (T2D) patients...
  28. Neumann T, Lodes S, Kästner B, Lehmann T, Hans D, Lamy O, et al. Trabecular bone score in type 1 diabetes--a cross-sectional study. Osteoporos Int. 2016;27:127-33 pubmed publisher
    Trabecular bone score (TBS) seems to provide additive value on BMD to identify individuals with prevalent fractures in T1D...
  29. Castejón N, Khalaf K, Ni Q, Cuervo J, Patrick D. Psychometric properties of the incontinence utility index among patients with idiopathic overactive bladder: data from two multicenter, double-blind, randomized, Phase 3, placebo-controlled clinical trials. Health Qual Life Outcomes. 2015;13:116 pubmed publisher
    ..001) were found in IUI scores for patients improving according to the Treatment Benefit Scale (TBS). Moderate to strong correlations (rho > |0...
  30. Bostancı A, Turhan M. A systematic review of tongue base suspension techniques as an isolated procedure or combined with uvulopalatopharyngoplasty in obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2016;273:2895-901 pubmed publisher
    We aimed to evaluate existing research into the effectiveness and safety of two tongue base suspension (TBS) techniques (Repose(®) system and modified TBS) with or without uvulopalatopharyngoplasty (UPPP) in obstructive sleep apnea...
  31. Mosca L, Cejka J, Dolenský B, Havlík M, Jakubek M, Kaplánek R, et al. Bowl-shaped Tröger's bases and their recognition properties. Chem Commun (Camb). 2016;52:10664-7 pubmed publisher
    The tris-Tröger's bases (TBs) are electron-rich fluorescent concave receptors due to the incorporation of naphthalene or triphenylene moieties (calix-1 and calix-2)...
  32. Lima J, Nobrega L, Lima N, Dos Santos M, Baracho M, Winzenrieth R, et al. Normal bone density and trabecular bone score, but high serum sclerostin in congenital generalized lipodystrophy. Bone. 2017;101:21-25 pubmed publisher
    ..We aimed to evaluate serum sclerostin, bone mineral density (BMD), and L1-L4 Trabecular Bone Score (TBS) in BSCL patients, generating new knowledge about potential mechanisms involved in the bone alterations of these ..
  33. Tsai J, Jiang L, Lee H, Hans D, Leder B. Effects of Teriparatide, Denosumab, or Both on Spine Trabecular Microarchitecture in DATA-Switch: a Randomized Controlled Trial. J Clin Densitom. 2017;20:507-512 pubmed publisher
    ..Subjects who received both drugs received an additional 24 mo of denosumab alone. Spine trabecular bone score (TBS, a gray-level textural assessment of bone microarchitecture) was measured blinded from treatment groups using ..
  34. Baldini M, Casirati G, Ulivieri F, Cassinerio E, Khouri Chalouhi K, Poggiali E, et al. Skeletal involvement in type 1 Gaucher disease: Not just bone mineral density. Blood Cells Mol Dis. 2018;68:148-152 pubmed publisher
    ..and macroscopic geometry, using two innovative dual-energy X-ray absorptiometry tools: Trabecular Bone Score (TBS) and Hip Structural Analysis (HSA). Bone quality parameters distinguished the patients with skeletal complications...
  35. Rachid F. Safety and Efficacy of Theta-Burst Stimulation in the Treatment of Psychiatric Disorders: A Review of the Literature. J Nerv Ment Dis. 2017;205:823-839 pubmed publisher
    Theta-burst stimulation (TBS) is a form of repetitive transcranial magnetic stimulation and is thought to induce more rapid and longer-lasting effects on synaptic plasticity than conventional repetitive transcranial magnetic stimulation ..
  36. Choi Y, Ock S, Jin Y, Lee J, Kim S, Chung Y. Urinary Pentosidine levels negatively associates with trabecular bone scores in patients with type 2 diabetes mellitus. Osteoporos Int. 2018;29:907-915 pubmed publisher
    ..Trabecular bone score (TBS) has been proposed as an index of bone microarchitecture associated with bone quality...
  37. Syrjänen K, Shabalova I, Ivanchenko O, Kljukina L, Grunberga V, Syrjänen S. Reproducibility of classification and correction for verification bias as determinants of performance of Papanicolaou smear cytology in the screening setting: experience from the New Independent States of the former Soviet Union cohort study. Acta Cytol. 2009;53:548-57 pubmed
    ..impact on interlaboratory agreement of 2 optional modes to convert Papanicolaou classification to Bethesda System (TBS) and demonstrate effect of verification bias correction on test performance in the New Independent States of the ..
  38. Herlin M, McGuigan F, Luthman H, Ã…kesson K. Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly. Bone. 2015;79:105-9 pubmed publisher
    ..Bone mineral density (BMD) and quantitative ultrasound (QUS) were analyzed in both cohorts; trabecular bone score (TBS) in PEAK-25; bone loss, fracture incidence and serum C-reactive protein (CRP) were assessed in OPRA...
  39. Romagnoli E, Lubrano C, Carnevale V, Costantini D, Nieddu L, Morano S, et al. Assessment of trabecular bone score (TBS) in overweight/obese men: effect of metabolic and anthropometric factors. Endocrine. 2016;54:342-347 pubmed
    The "trabecular bone score" (TBS) indirectly explores bone quality, independently of bone mineral density (BMD). We investigated the effects of anthropometric and metabolic parameters on TBS in 87 overweight/obese men...
  40. Liu Y, Wang Y, Zhu G, Sun J, Bi X, Baudry M. A calpain-2 selective inhibitor enhances learning & memory by prolonging ERK activation. Neuropharmacology. 2016;105:471-477 pubmed publisher
    While calpain-1 activation is required for LTP induction by theta burst stimulation (TBS), calpain-2 activation limits its magnitude during the consolidation period...
  41. Pitcher D, Japee S, Rauth L, Ungerleider L. The Superior Temporal Sulcus Is Causally Connected to the Amygdala: A Combined TBS-fMRI Study. J Neurosci. 2017;37:1156-1161 pubmed publisher
    ..Here, we addressed this question by combining theta burst transcranial magnetic stimulation (TBS) with fMRI to test the prediction that the STS and amygdala are functionally connected during face perception...
  42. Matsumoto H, Yamashita M, Tahara T, Hayakawa S, Wada S, Tomioka K, et al. Design, synthesis, and evaluation of DNA topoisomerase II-targeted nucleosides. Bioorg Med Chem. 2017;25:4133-4144 pubmed publisher
    ..Moreover, nucleoside analogues containing TBS and 1,3-dithian moieties had potent and selective DNA topoisomerase II inhibitory activities...
  43. Ceciliason A, Andersson M, Lindström A, Sandler H. Quantifying human decomposition in an indoor setting and implications for postmortem interval estimation. Forensic Sci Int. 2018;283:180-189 pubmed publisher
    ..prospectively from 140 forensic cases with a known date of death, scored according to the Total Body Score (TBS) scale at the post-mortem examination...
  44. Lecce F, Walsh V, Didino D, Cappelletti M. 'How many' and 'how much' dissociate in the parietal lobe. Cortex. 2015;73:73-9 pubmed publisher
    ..numerosity discrimination task after receiving continuous theta burst transcranial magnetic stimulation (TBS) over the left or right intraparietal sulcus (IPS) or the Vertex...
  45. Lorenzo L, Bonillo M, Arlandis S, Martínez Cuenca E, Marzullo L, Broseta E, et al. Hydrodistension plus Onabotulinumtoxin A in bladder pain syndrome refractory to conservative treatments. Actas Urol Esp. 2016;40:303-8 pubmed publisher
    ..To study the clinical change, we evaluated the subjective improvement (Treatment Benefit Scale [TBS] and Patient Global Impression of Change [PGIC] scales), the visual analogue scale (VAS) for pain, the Bladder Pain/..
  46. Jeena M, Bok T, Kim S, Park S, Kim J, Park S, et al. A siloxane-incorporated copolymer as an in situ cross-linkable binder for high performance silicon anodes in Li-ion batteries. Nanoscale. 2016;8:9245-53 pubmed publisher
    ..Twenty-one percent of TEVS in the TBS-TEVS copolymer gave rise to a superior performance as a binder for Si anodes, where the anodes showed a stable ..
  47. Holloway K, Mohebbi M, Betson A, Hans D, Hyde N, Brennan Olsen S, et al. Prediction of major osteoporotic and hip fractures in Australian men using FRAX scores adjusted with trabecular bone score. Osteoporos Int. 2018;29:101-108 pubmed publisher
    ..for either major osteoporotic or hip fracture FRAX scores when comparing the unadjusted and trabecular bone score (TBS)-adjusted scores. FRAX 10-year probability of fracture can be calculated with adjustment for the TBS...
  48. Psykarakis E, Chatzopoulou E, Gimisis T. First characterisation of two important postulated intermediates in the formation of a HydT DNA lesion, a thymidine oxidation product. Org Biomol Chem. 2018;16:2289-2300 pubmed publisher
    ..intermediate, was produced by the ozonolysis reaction of 2',3',5'-tri-O-acetylribo-, 3',5'-di-O-TBS- and N3,O3',O5-tribenzyl-protected thymidines and was shown to produce, upon decomposition and depending on the ..
  49. LeBaron R, Hernandez R, Orfila J, Martinez J. An integrin binding peptide reduces rat CA1 hippocampal long-term potentiation during the first few minutes following theta burst stimulation. Neurosci Lett. 2003;339:199-202 pubmed
    ..Experiments in which GRGDSP was bath applied for 50 min, beginning 10 min before theta burst stimulation (TBS), reduced LTP of the field excitatory post synaptic potential in a concentration dependent manner, with 250 microM ..
  50. Reardon W, Casserly L, Birkenhäger R, Kohlhase J. Kidney failure in Townes-Brocks syndrome: an under recognized phenomenon?. Am J Med Genet A. 2007;143A:2588-91 pubmed
    ..While the SALL1 gene, mutations of which result in the Townes-Brocks phenotype, is expressed in the developing kidney, the absence ..
  51. Currie S, Körtner G, Geiser F. Measuring subcutaneous temperature and differential rates of rewarming from hibernation and daily torpor in two species of bats. Comp Biochem Physiol A Mol Integr Physiol. 2015;190:26-31 pubmed publisher
    ..temperature (Tsub) during daily torpor in a small marsupial, no study has attempted to use these devices at Tbs below 10°C...
  52. Marchal E, Figliola C, Thompson A. Prodigiosenes conjugated to tamoxifen and estradiol. Org Biomol Chem. 2017;15:5410-5427 pubmed publisher
    ..Specifically, and important to synthesis involving estradiol, TBS, TMS and THP are not useful protecting groups for the functionalisation of this core...
  53. Librizzi M, Guadalix S, Martínez Díaz Guerra G, Allo G, Lora D, Jimenez C, et al. Trabecular bone score in patients with liver transplants after 1 year of risedronate treatment. Transpl Int. 2016;29:331-7 pubmed publisher
    ..In this retrospective cohort study, trabecular bone score (TBS) was calculated from dual X-ray absorptiometry images of the lumbar spine (LS), collected from a prospective ..
  54. Ciardo A, El Assawy N, Mauro S, Priano L. Effects of acoustic stimulus duration on cervical vestibular evoked myogenic potentials: A neurophysiological and modeling study. J Vestib Res. 2016;26:359-374 pubmed
    ..Subjects with normal hearing and no vestibular or cervical disorders were tested using 1?kHz tone bursts (TBs) of different durations to evoke cVEMPs from the ipsilateral sternocleidomastoid muscle...
  55. Niño C, Cubides J, Camargo Ayala P, Rodríguez Celis C, Quiñones T, Cortés Castillo M, et al. Plasmodium malariae in the Colombian Amazon region: you don't diagnose what you don't suspect. Malar J. 2016;15:576 pubmed
    ..from symptomatic patients in Colombia's Amazon department were analysed in parallel by thick blood smear (TBS) test and nested PCR for determining Plasmodium spp...
  56. Marsili L, Suppa A, Di Stasio F, Belvisi D, Upadhyay N, Berardelli I, et al. BDNF and LTP-/LTD-like plasticity of the primary motor cortex in Gilles de la Tourette syndrome. Exp Brain Res. 2017;235:841-850 pubmed publisher
    ..We also compared responses to TBS according to BDNF polymorphism (Val/Val vs Met carriers) in patients and controls...
  57. Geraldeli S, Soares E, Alvarez A, Farivar T, Shields R, Sinhoreti M, et al. A new arginine-based dental adhesive system: formulation, mechanical and anti-caries properties. J Dent. 2017;63:72-80 pubmed publisher
    ..of elasticity (E), degree of conversion (DC), Knoop hardness number (KHN) and dentin microtensile bond strength (?-TBS), (ii) arginine release and recharge, and (iii) antibacterial activities...
  58. Sritara C, Thakkinstian A, Ongphiphadhanakul B, Amnuaywattakorn S, Utamakul C, Akrawichien T, et al. Age-Adjusted Dual X-ray Absorptiometry-Derived Trabecular Bone Score Curve for the Lumbar Spine in Thai Females and Males. J Clin Densitom. 2016;19:494-501 pubmed publisher
    Trabecular bone score (TBS), which has been shown to discriminate patients with fractures from healthy individuals, decreases with age...
  59. Popp A, Meer S, Krieg M, Perrelet R, Hans D, Lippuner K. Bone mineral density (BMD) and vertebral trabecular bone score (TBS) for the identification of elderly women at high risk for fracture: the SEMOF cohort study. Eur Spine J. 2016;25:3432-3438 pubmed
    To determine the predictive value of the vertebral trabecular bone score (TBS) alone or in addition to bone mineral density (BMD) with regard to fracture risk...
  60. Li S, Xu F, Li H, Zhang J, Zhong A, Huang B, et al. S100A8+ stroma cells predict a good prognosis and inhibit aggressiveness in colorectal carcinoma. Oncoimmunology. 2017;6:e1260213 pubmed publisher
    ..and bioinformatic analysis showed that S100A8 was more abundant in the stroma surrounding tumor buddings (TBs) than in the stroma surrounding primary tumor cells in colorectal carcinomas...
  61. Krania P, Dimou E, Bantouna M, Kouvaros S, Tsiamaki E, Papatheodoropoulos C, et al. Adenosine A2A receptors are required for Glutamate mGluR5- and Dopamine D1 receptor-evoked ERK1/2 phosphorylation in rat Hippocampus: Involvement of NMDA receptor. J Neurochem. 2017;: pubmed publisher
    ..Our biochemical results are supported by electrophysiological data showing, that in CA1 region of hippocampus, the TBS-induced LTP coincides temporally with an increase in ERK1/2 activation and both phenomena are dependent on the ..
  62. Hatoum I, Greenawalt D, Cotsapas C, Daly M, Reitman M, Kaplan L. Weight loss after gastric bypass is associated with a variant at 15q26.1. Am J Hum Genet. 2013;92:827-34 pubmed publisher
    ..These findings provide strong evidence for specific genetic influences on weight loss after RYGB and underscore the biological nature of the response to RYGB. ..
  63. McClung M, Lippuner K, Brandi M, Zanchetta J, Bone H, Chapurlat R, et al. Effect of denosumab on trabecular bone score in postmenopausal women with osteoporosis. Osteoporos Int. 2017;28:2967-2973 pubmed publisher
    Trabecular bone score (TBS) assesses bone quality in the lumbar spine using dual-energy X-ray absorptiometry (DXA) scans...
  64. Bertelsen M, Mohammed O, Wang T, Manger P, Scantlebury D, Ismael K, et al. The hairy lizard: heterothermia affects anaesthetic requirements in the Arabian oryx (Oryx leucoryx). Vet Anaesth Analg. 2017;44:899-904 pubmed publisher
    ..six anaesthetized oryx, expiratory gasses for oxygen analysis and metabolic rate calculation were collected at two Tbs; before and after submersion in ice water for approximately 30 minutes...
  65. Wendler M, Belli R, Panzer R, Skibbe D, Petschelt A, Lohbauer U. Repair Bond Strength of Aged Resin Composite after Different Surface and Bonding Treatments. Materials (Basel). 2016;9: pubmed publisher
    ..the effect of different mechanical surface treatments and chemical bonding protocols on the tensile bond strength (TBS) of aged composite...
  66. Herrera S, Soriano R, Nogues X, Güerri Fernández R, Grinberg D, Garcia Giralt N, et al. Discrepancy between bone density and bone material strength index in three siblings with Camurati-Engelmann disease. Osteoporos Int. 2017;28:3489-3493 pubmed publisher
    ..In three siblings with CE disease, we aimed to assess bone mineral density (BMD) and trabecular bone score (TBS) by dual-energy X-ray absorptiometry (DXA) and material characteristics at tissue level using bone impact reference ..
  67. Choi Y, Chung Y, Suh C, Jung J, Kim H. Trabecular bone score as a supplementary tool for the discrimination of osteoporotic fractures in postmenopausal women with rheumatoid arthritis. Medicine (Baltimore). 2017;96:e8661 pubmed publisher
    ..The trabecular bone score (TBS) is a new indirect parameter of bone quality...
  68. Nishimura K, Sakaguchi T, Nanba Y, Suganuma Y, Morita M, Hong S, et al. Stereoselective Total Synthesis of Macrophage-produced Prohealing 14,21-Dihydroxydocosahexaenoic Acids. J Org Chem. 2017;: pubmed publisher
    ..salt, which was subjected to a Wittig reaction with racemic C16-aldehyde of the C12-C16 part with the TMS and TBS-oxy groups at C12 and C14, yielding the C12-C22 derivative with 14R/S and 21R chirality...
  69. Izumi K, Aramaki M, Kimura T, Naito Y, Udaka T, Uchikawa M, et al. Identification of a prosencephalic-specific enhancer of SALL1: comparative genomic approach using the chick embryo. Pediatr Res. 2007;61:660-5 pubmed
    ..Here we performed a survey for conserved noncoding elements (CNE) nested within the SALL1 gene; mutations in this gene result in the Townes-Brocks syndrome...
  70. Shen H, Sabaliauskas N, Yang L, Aoki C, Smith S. Role of α4-containing GABAA receptors in limiting synaptic plasticity and spatial learning of female mice during the pubertal period. Brain Res. 2017;1654:116-122 pubmed publisher
    ..Induction of LTP, in response to stimulation of the Schaffer collaterals with theta burst stimulation (TBS), was unsuccessful in the +/+ hippocampus, but reinstated by α4 knock-out (~65% potentiation) but not by ..
  71. Jones C, Lulic T, Bailey A, Mackenzie T, Mi Y, Tommerdahl M, et al. Metaplasticity in human primary somatosensory cortex: effects on physiology and tactile perception. J Neurophysiol. 2016;115:2681-91 pubmed publisher
    Theta-burst stimulation (TBS) over human primary motor cortex evokes plasticity and metaplasticity, the latter contributing to the homeostatic balance of excitation and inhibition...
  72. Jin X, Homaei E, Matinlinna J, Tsoi J. A new concept and finite-element study on dental bond strength tests. Dent Mater. 2016;32:e238-e250 pubmed publisher
    ..to simulate and compare the stress distribution of and between shear bond strength (SBS), tensile bond strength (TBS), mold-enclosed shear bond strength (ME-SBS) and de novo lever-induced mold-enclosed shear bond strength (LIME-SBS) ..
  73. Shevroja E, Lamy O, Kohlmeier L, Koromani F, Rivadeneira F, Hans D. Use of Trabecular Bone Score (TBS) as a Complementary Approach to Dual-energy X-ray Absorptiometry (DXA) for Fracture Risk Assessment in Clinical Practice. J Clin Densitom. 2017;20:334-345 pubmed publisher
    ..the bone and fails in measuring bone microarchitecture, for which novel techniques, such as trabecular bone score (TBS), have been developed...
  74. Ebina K, Hirao M, Hashimoto J, Hagihara K, Kashii M, Kitaguchi K, et al. Assessment of the effects of switching oral bisphosphonates to denosumab or daily teriparatide in patients with rheumatoid arthritis. J Bone Miner Metab. 2018;36:478-487 pubmed publisher
    ..01). Moreover, the switch-to-TPTD group showed a higher LS BMD (P < 0.05) and trabecular bone score (TBS) (2.1 vs -0.7%; P < 0.05) increase than the switch-to-DMAb group...
  75. Lümkemann N, Eichberger M, Stawarczyk B. Bonding to Different PEEK Compositions: The Impact of Dental Light Curing Units. Materials (Basel). 2017;10: pubmed publisher
    ..link (VL) on the tensile bond strength (TBS) of different PEEK compositions...
  76. Hong M, Kim J, Shin M, Kim B. Poorly Differentiated Clusters in Colorectal Adenocarcinomas Share Biological Similarities with Micropapillary Patterns as well as Tumor Buds. J Korean Med Sci. 2017;32:1595-1602 pubmed publisher
    ..show morphological continuity and behavioral similarities to micropapillary patterns (MPPs) as well as tumor buds (TBs)...
  77. Lee J, Kim K, Kim L, Kim K, Oh T, Moon J, et al. Comparisons of TBS and lumbar spine BMD in the associations with vertebral fractures according to the T-scores: A cross-sectional observation. Bone. 2017;105:269-275 pubmed publisher
    Trabecular bone score (TBS) is a parameter of bone quality that has been shown to be related to vertebral fractures...
  78. Krajcovicova A, Kuzma M, Hlavaty T, Hans D, Koller T, Jackuliak P, et al. Decrease of trabecular bone score reflects severity of Crohn's disease: results of a case-control study. Eur J Gastroenterol Hepatol. 2018;30:101-106 pubmed publisher
    ..The trabecular bone score (TBS) provides an indirect measurement of bone microarchitecture, independent of bone mineral density (BMD)...
  79. Tan Y, Hu J, Ren L, Zhu J, Yang J, Liu D. A Passive and Wireless Sensor for Bone Plate Strain Monitoring. Sensors (Basel). 2017;17: pubmed publisher
    ..In order to verify the effectiveness of the sensor, a tibia-bone plate-screw (TBS) model was established using the finite element analysis method...
  80. de Souza Granja Barros J, Rossi L, Menezes de Souza Z. PID temperature controller in pig nursery: spatial characterization of thermal environment. Int J Biometeorol. 2018;62:773-781 pubmed publisher
    ..We evaluated the climatic variables: dry bulb temperature (Tbs), air relative humidity (RH), temperature and humidity index (THI), and enthalpy in the winter, at 7:00, 12:00, and ..
  81. Netzer C, Bohlander S, Rieger L, Muller S, Kohlhase J. Interaction of the developmental regulator SALL1 with UBE2I and SUMO-1. Biochem Biophys Res Commun. 2002;296:870-6 pubmed
    Mutations in the SALL1 gene on chromosome 16q12.1 cause Townes-Brocks syndrome (TBS)...
  82. Liang Y, Shen D, Cai W. Two coding single nucleotide polymorphisms in the SALL1 gene in Townes-Brocks syndrome: a case report and review of the literature. J Pediatr Surg. 2008;43:391-3 pubmed publisher
    ..Mutations in SALL1, a gene mapping to chromosome 16q21.1, are responsible for TBS...
  83. Goodin K, Prucka S, Woolley A, Kohlhase J, Smith R, Grant J, et al. Familial transmission of oculoauriculovertebral spectrum (Goldenhar syndrome) is not due to mutations in either EYA1 or SALL1. Am J Med Genet A. 2009;149A:535-8 pubmed publisher
  84. Dehghan A, Dupuis J, Barbalic M, Bis J, Eiriksdottir G, Lu C, et al. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011;123:731-8 pubmed publisher
    ..IL1F10, and IRF1) or that reside in regions previously not known to play a role in chronic inflammation (PPP1R3B, SALL1, PABPC4, ASCL1, RORA, and BCL7B). We found a significant interaction of body mass index with LEPR (P<2...
  85. Kobayashi Y, Saito Y, Goto M, Nakagawa Goto K. Antitubulin effects of aminobenzothiophene-substituted triethylated chromones. Bioorg Med Chem Lett. 2017;27:2731-2735 pubmed publisher
    ..Among all newly synthesized amino-TEDB-TBs, the 5'- and 6'-amino derivatives, 6 and 7, exhibited significant antiproliferative activity against five human ..
  86. Shetty A, Viswanathan V, Kanna R, Shanmuganathan R. Tubercular spondylodiscitis in elderly is a more severe disease: a report of 66 consecutive patients. Eur Spine J. 2017;26:3178-3186 pubmed publisher
    1) To analyze peculiarities of presentation and prognosis of tubercular spondylodiscitis (TBS) in elderly...
  87. Ruan X, Xu G, Gao C, Liu L, Liu Y, Jiang L, et al. Alterations of the amplitude of low-frequency fluctuation in healthy subjects with theta-burst stimulation of the cortex of the suprahyoid muscles. Neuroscience. 2017;365:48-56 pubmed publisher
    Theta burst stimulation (TBS) has emerged as a promising tool for the treatment of swallowing disorders; however, the short-term after-effects of brain activation induced by TBS remain unknown...
  88. Tung P, Zhong C, Chien T, Yeh M. Synthesis of Spirolactams and Fused Bicyclic Lactams via Acid-Promoted Cyclolactamization of (Ethynyl(tosyl)amino)methyl-Tethered Cyclohex-2-enols. J Org Chem. 2017;82:11543-11557 pubmed publisher
    ..This strategy could also be employed in the synthesis of fused bicyclic lactams from BF3·OEt2-assisted cyclolactamization of TBS-protected 2-(ethynyl(tosyl)amino)methylcyclohex-2-enols.
  89. Pereira S, Jerônimo G, Marchiori N, Oliveira H, Jesus G, Schmidt E, et al. Tadpoles fed supplemented diet with probiotic bacterium isolated from the intestinal tract of bullfrog Lithobates catesbeianus: Haematology, cell activity and electron microscopy. Microb Pathog. 2018;114:255-263 pubmed publisher
    ..pathogenic bacteria (ANT), antimicrobial activity from extracellular compounds (MIC), tolerance to bile salts (TBS), pH reduction, protease production, sensitivity to antimicrobial tetracycline, cell viability, growth rate and ..
  90. Borralleras C, Mato S, Amédée T, Matute C, Mulle C, Perez Jurado L, et al. Synaptic plasticity and spatial working memory are impaired in the CD mouse model of Williams-Beuren syndrome. Mol Brain. 2016;9:76 pubmed publisher
    ..We have found that long-term potentiation (LTP) elicited by theta burst stimulation (TBS) was significantly impaired in hippocampal field CA1 of CD animals...
  91. Osella G, Priola A, Priola S, Piga A, Longo F, Ventura M, et al. Dual-Energy X-ray Absorptiometry Predictors of Vertebral Deformities in Beta-Thalassemia Major. J Clin Densitom. 2018;21:507-516 pubmed publisher
    ..patients and to identify their best dual-energy X-ray absorptiometry (DXA) predictor among trabecular bone score (TBS), bone mineral density (BMD), and Z-score...
  92. Hyde N, Brennan Olsen S, Wark J, Hosking S, Holloway K, Pasco J. Maternal vitamin D and offspring trabecular bone score. Osteoporos Int. 2017;28:3407-3414 pubmed publisher
    ..have explored the relationship with maternal vitamin D (25(OH)D) in pregnancy and offspring trabecular bone score (TBS)...