RTP2

Summary

Gene Symbol: RTP2
Description: receptor transporter protein 2
Alias: Z3CXXC2, receptor-transporting protein 2, 3CxxC-type zinc finger protein 2, receptor (chemosensory) transporter protein 2, zinc finger, 3CxxC-type 2
Species: human
Products:     RTP2

Top Publications

  1. Saito H, Kubota M, Roberts R, Chi Q, Matsunami H. RTP family members induce functional expression of mammalian odorant receptors. Cell. 2004;119:679-91 pubmed
    ..Here we show that the transmembrane proteins RTP1 and RTP2 promote functional cell surface expression of ORs expressed in HEK293T cells...
  2. Clark A, Metherell L, Cheetham M, Huebner A. Inherited ACTH insensitivity illuminates the mechanisms of ACTH action. Trends Endocrinol Metab. 2005;16:451-7 pubmed
    ..Molecular defects underlying other causes of ACTH insensitivity syndromes will probably contribute further to our understanding of these pathways. ..
  3. Behrens M, Bartelt J, Reichling C, Winnig M, Kuhn C, Meyerhof W. Members of RTP and REEP gene families influence functional bitter taste receptor expression. J Biol Chem. 2006;281:20650-9 pubmed
    ..Finally, expression analyses demonstrate RTP and REEP gene expression in human circumvallate papillae and testis, both of which are sites of TAS2R gene expression. ..
  4. Sharma R, Ishimaru Y, Davison I, Ikegami K, Chien M, You H, et al. Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice. elife. 2017;6: pubmed publisher
    ..i>Rtp1 and Rtp2 double knockout mice (RTP1,2DKO) show OR trafficking defects and decreased OSN activation...
  5. Yu T, Su X, Pan Y, Zhuang H. Receptor-transporting protein (RTP) family members play divergent roles in the functional expression of odorant receptors. PLoS ONE. 2017;12:e0179067 pubmed publisher
    Receptor transporting protein (RTP) family members, RTP1S and RTP2, are accessory proteins to mammalian odorant receptors (ORs)...