RTN1

Summary

Gene Symbol: RTN1
Description: reticulon 1
Alias: NSP, reticulon-1, neuroendocrine-specific protein
Species: human
Products:     RTN1

Top Publications

  1. Tagami S, Eguchi Y, Kinoshita M, Takeda M, Tsujimoto Y. A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity. Oncogene. 2000;19:5736-46 pubmed
    ..We identified two members of the reticulon (RTN) family as Bcl-XL binding proteins, i.e., NSP-C (RTN1-C) and a new family member, RTN-XS, both of which did not belong to the Bcl-2 family and were predominantly ..
  2. Yan R, Shi Q, Hu X, Zhou X. Reticulon proteins: emerging players in neurodegenerative diseases. Cell Mol Life Sci. 2006;63:877-89 pubmed
    ..In mammalian genomes, transcripts are produced from four genes, rtn1 to rtn4, under the regulation of tissue or cell-type-specific expression...
  3. Di Sano F, Fazi B, Tufi R, Nardacci R, Piacentini M. Reticulon-1C acts as a molecular switch between endoplasmic reticulum stress and genotoxic cell death pathway in human neuroblastoma cells. J Neurochem. 2007;102:345-53 pubmed
    ..These data indicate that RTN-1C is able to modulate the cellular sensitivity to different apoptotic pathways representing a promising molecular target for new drug development. ..
  4. Steiner P, Kulangara K, Sarria J, Glauser L, Regazzi R, Hirling H. Reticulon 1-C/neuroendocrine-specific protein-C interacts with SNARE proteins. J Neurochem. 2004;89:569-80 pubmed
    ..Here, we show that reticulon 1-C can be detected in a protein complex of 150-200 kDa, and that a number of soluble N-ethylmaleimide-sensitive ..
  5. He W, Lu Y, Qahwash I, Hu X, Chang A, Yan R. Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. Nat Med. 2004;10:959-65 pubmed
    ..The reticulon family of proteins has four members, RTN1, RTN2, RTN3 and RTN4 (also known as Nogo), the last of which is well known for its role in inhibiting neuritic ..
  6. Fazi B, Melino S, De Rubeis S, Bagni C, Paci M, Piacentini M, et al. Acetylation of RTN-1C regulates the induction of ER stress by the inhibition of HDAC activity in neuroectodermal tumors. Oncogene. 2009;28:3814-24 pubmed publisher
    ..These data demonstrate a molecular mechanism by which RTN-1C controls apoptosis and indicate this protein to be a novel potential target for cancer therapy...
  7. Fazi B, Biancolella M, Mehdawy B, Corazzari M, Minella D, Blandini F, et al. Characterization of gene expression induced by RTN-1C in human neuroblastoma cells and in mouse brain. Neurobiol Dis. 2010;40:634-44 pubmed publisher
    ..These data provide a basis for further investigation of RTN-1C as a potential molecular target for use in therapy and as a specific marker for neurological diseases. ..
  8. Vayssiere C, Gaudineau A, Attali L, Bettahar K, Eyraud S, Faucher P, et al. [Induced abortion: Guidelines for clinical practice - Text of the Guidelines (short text)]. J Gynecol Obstet Biol Reprod (Paris). 2016;45:1596-1603 pubmed publisher
    ..Early initiation and choice of contraception in connection to the woman's life are associated with lower NSP. Reversible contraceptives of long duration of action should be positioned fist in line for the teenager because of ..
  9. Bielke L, Hargis B, Latorre J. Impact of Enteric Health and Mucosal Permeability on Skeletal Health and Lameness in Poultry. Adv Exp Med Biol. 2017;1033:185-197 pubmed publisher
    ..Consumption of diets with a high content of soluble non-starch polysaccharides (NSP) can affect bone quality parameters by reducing the amount of conjugated bile acids in the intestine, therefore ..

More Information

Publications132 found, 100 shown here

  1. Nasar F, Gorchakov R, Tesh R, Weaver S. Eilat virus host range restriction is present at multiple levels of the virus life cycle. J Virol. 2015;89:1404-18 pubmed publisher
    ..that the EILV host range restriction is multigenic, involving at least one gene from both nonstructural protein (nsP) and structural protein (sP) open reading frames (ORFs)...
  2. Nilsson A, Johansson Boll E, Björck I. Increased gut hormones and insulin sensitivity index following a 3-d intervention with a barley kernel-based product: a randomised cross-over study in healthy middle-aged subjects. Br J Nutr. 2015;114:899-907 pubmed publisher
    ..and ameliorate appetite control and glycaemic control by ingestion of a whole-grain cereal food product rich in NSP and resistant starch in healthy humans...
  3. Gulyaeva A, Dunowska M, Hoogendoorn E, Giles J, Samborskiy D, Gorbalenya A. Domain Organization and Evolution of the Highly Divergent 5' Coding Region of Genomes of Arteriviruses, Including the Novel Possum Nidovirus. J Virol. 2017;91: pubmed publisher
    ..arterivirus species, the 5'-end genome coding region encodes the most divergent nonstructural proteins (nsp's), nsp1 and nsp2, which include papain-like proteases (PLPs) and other poorly characterized domains...
  4. Gao S, Zuo X, Liu D, Xiao Y, Zhu H, Zhang H, et al. The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies. Arthritis Res Ther. 2018;20:134 pubmed publisher
    ..Serum NSPs degraded the VE-cadherin of HDMECs, and serum NSP application increased the permeability of HDMECs...
  5. Pleuger C, Fietz D, Hartmann K, Schuppe H, Weidner W, Kliesch S, et al. Expression of ciliated bronchial epithelium 1 during human spermatogenesis. Fertil Steril. 2017;108:47-54 pubmed publisher
    ..Forty-three human testicular biopsies: 12 biopsies showing normal spermatogenesis (NSP), 8 with maturation arrest at level of spermatocytes (STA), 8 with maturation arrest at level of spermatids (SDA), ..
  6. Hurst Hess K, Kuo L, Masters P. Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3. J Virol. 2015;89:6033-47 pubmed publisher
    ..mouse hepatitis virus (MHV) is carried out by a replicase-transcriptase composed of 16 nonstructural protein (nsp) subunits. Among these, nsp3 is the largest and the first to be inserted into the endoplasmic reticulum...
  7. Pearson W, Ovalle F, Faul M, Sasser S. A review of traumatic brain injury trauma center visits meeting physiologic criteria from The American College of Surgeons Committee on Trauma/Centers for Disease Control and Prevention Field Triage Guidelines. Prehosp Emerg Care. 2012;16:323-8 pubmed publisher
    ..The data for this study were taken from the 2007 National Trauma Data Bank (NTDB) National Sample Program (NSP)...
  8. Wiessing L, Ferri M, Belackova V, Carrieri P, Friedman S, Folch C, et al. Monitoring quality and coverage of harm reduction services for people who use drugs: a consensus study. Harm Reduct J. 2017;14:19 pubmed publisher
    ..Twelve priority candidate indicators are proposed for opioid agonist therapy (OAT), needle and syringe programmes (NSP) and generic cross-cutting aspects of harm reduction (and potentially other drug) services...
  9. Bagheri M, Norouzi H, Hossienizadeh S, Es Haghi A, Ghassempour A. Development and modeling of two-dimensional fast protein liquid chromatography for producing nonstructural protein-free food-and-mouth diseases virus vaccine. J Chromatogr B Analyt Technol Biomed Life Sci. 2018;1096:113-121 pubmed publisher
    ..the capability of SEC media for separating two critical impurities (residual DNA (rDNA) and non-structural protein (NSP)) from active ingredient of vaccine (FMDV particle)...
  10. Oudshoorn D, Rijs K, Limpens R, Groen K, Koster A, Snijder E, et al. Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication. MBio. 2017;8: pubmed publisher
    ..Previous evidence suggested that the nonstructural proteins (nsp's) 3, 4, and 6 of the severe acute respiratory syndrome coronavirus (SARS-CoV), which contain transmembrane domains,..
  11. Zheng D, Chen H, Bartee M, Williams J, Davids J, Lomas D, et al. Myxomaviral Anti-Inflammatory Serpin Reduces Myeloid-Derived Suppressor Cells and Human Pancreatic Cancer Cell Growth in Mice. J Cancer Sci Ther. 2013;5:291-299 pubmed
    ..009), without detected change in other splenocyte subpopulations. Serp-1 and NSP treatment also significantly reduced macrophage infiltration in tumors (P=0.001)...
  12. Elnekave E, Van Maanen K, Shilo H, Gelman B, Storm N, Berdenstain S, et al. Prevalence and risk factors for foot and mouth disease infection in small ruminants in Israel. Prev Vet Med. 2016;125:82-8 pubmed publisher
    ..The serological prevalence of antibodies against non structural proteins (NSP) of FMD virus was estimated at 3.7% (95% confidence interval (CI95%)=3.0% -4.5%)...
  13. Wang G, Xia Y, Xiong Z, Zhang H, Ai L. Use of a Novel Report Protein to Study the Secretion Signal of Flagellin in Bacillus subtilis. Curr Microbiol. 2016;73:242-7 pubmed publisher
    ..subtilis. The naturally nonsecretory, intrinsically disordered domain of nucleoskeletal-like protein (Nsp) was used as the reporter protein...
  14. Sulayeman M, Dawo F, Mammo B, Gizaw D, Shegu D. Isolation, molecular characterization and sero-prevalence study of foot-and-mouth disease virus circulating in central Ethiopia. BMC Vet Res. 2018;14:110 pubmed publisher
    ..using an ELISA for antibodies against non-structural proteins of FMDV based on the 3ABC proteins (ID Screen® FMD NSP Competition, ID-VET, Grabels, France)...
  15. Yuan S, Zhang N, Xu L, Zhou L, Ge X, Guo X, et al. Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus. PLoS ONE. 2016;11:e0156518 pubmed publisher
    ..Next, the PRRSV-encoded apoptosis inducers were screened, indicating that the nonstructural protein (Nsp) 4 and Nsp10 of PRRSV are pro-apoptotic...
  16. Abraham R, Hauer D, McPherson R, Utt A, Kirby I, Cohen M, et al. ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication. Proc Natl Acad Sci U S A. 2018;115:E10457-E10466 pubmed publisher
    Alphaviruses are plus-strand RNA viruses that cause encephalitis, rash, and arthritis. The nonstructural protein (nsP) precursor polyprotein is translated from genomic RNA and processed into four nsPs...
  17. Sansone M, Sansone A, Shiga T, Nascimento J. The water-soluble non-starch polysaccharides from bananas display immunomodulatory properties on cultured macrophages. Food Res Int. 2016;87:125-133 pubmed publisher
    ..The non-starch polysaccharides (NSP) from bananas are non-digestible carbohydrates that resemble some immunomodulatory polysaccharides occurring in the ..
  18. Krapp S, Schuy C, Greiner E, Stephan I, Alberter B, Funk C, et al. Begomoviral Movement Protein Effects in Human and Plant Cells: Towards New Potential Interaction Partners. Viruses. 2017;9: pubmed publisher
    ..For intra- and intercellular transport, two proteins are required: a nuclear shuttle protein (NSP) and a movement protein (MP)...
  19. Chen Y, Xing X, Li Q, Feng S, Han X, He S, et al. Serine 105 and 120 are important phosphorylation sites for porcine reproductive and respiratory syndrome virus N protein function. Vet Microbiol. 2018;219:128-135 pubmed publisher
    ..The Nsp(non-structural protein) 9 qPCR results were consistent with the multistep growth kinetics results...
  20. Chevaleyre C, Riou M, Bréa D, Vandebrouck C, Barc C, Pezant J, et al. The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection. PLoS ONE. 2016;11:e0168577 pubmed publisher
    ..These proteases were also detected at the surface of lung neutrophils using anti-human NSP antibodies...
  21. Wang M, Xu Z, Liu W, Li M, Wang H, Yang D, et al. Identification of a conserved linear epitope using monoclonal antibody against non-structural protein 3A of foot-and-mouth disease virus with potential for differentiation between infected and vaccinated animals. Res Vet Sci. 2019;124:178-185 pubmed publisher
    ..Non-structural protein (NSP) 3A of FMDV is as part of a larger detected antigen that is used for this differential diagnosis...
  22. Dill V, Eschbaumer M, Beer M, Hoffmann B. Inter-laboratory validation of foot-and-mouth disease diagnostic capability in Germany. Vet Microbiol. 2017;203:62-67 pubmed publisher
    ..of over 99% for the two commercial ELISA kits used (PrioCHECK® FMDV NS and ID Screen® FMD NSP)...
  23. Teye M, Sebunya T, Fana E, King D, Seoke L, Knowles N, et al. Foot-and-mouth disease in Southern Ghana: occurrence and molecular characterization of circulating viruses. Trop Anim Health Prod. 2019;: pubmed publisher
    ..Sera were analyzed using the PrioCHECK® FMDV non-structural protein (NSP) ELISA whereas the epithelia/oral swab samples were examined by virus isolation, antigen ELISA, reverse ..
  24. Wu X, Chen D, Yu B, Luo Y, Zheng P, Mao X, et al. Effect of different dietary non-starch fiber fractions on growth performance, nutrient digestibility, and intestinal development in weaned pigs. Nutrition. 2018;51-52:20-28 pubmed publisher
    ..05). This study not only indicated how the gut digestive physiology adapted to different NSP fractions, but also provided novel (to our knowledge) information that could promote our understanding of the role ..
  25. Deneka A, Korobeynikov V, Golemis E. Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members. Gene. 2015;570:25-35 pubmed publisher
    ..signaling, estrogen receptor signaling or cell cycle progression, involving discrete partner proteins such as SHC, NSP proteins, or AURKA...
  26. Li C, Liang W, Liu W, Yang D, Wang H, Ma W, et al. Identification of a conserved linear epitope using a monoclonal antibody against non-structural protein 3B of foot-and-mouth disease virus. Arch Virol. 2016;161:365-75 pubmed publisher
    ..Nonstructural protein (NSP) 3B of FMDV is part of a larger antigen that is used for this differential diagnosis...
  27. Eisenhauer P, Chernets N, Song Y, Dobrynin D, Pleshko N, Steinbeck M, et al. Chemical modification of extracellular matrix by cold atmospheric plasma-generated reactive species affects chondrogenesis and bone formation. J Tissue Eng Regen Med. 2016;10:772-82 pubmed publisher
    ..The commercially available ECM, Matrigel, was treated with microsecond or nanosecond pulsed (?sp or nsp, respectively) DBD frequencies conditions at the equivalent frequencies (1 kHz) or power (~1 W)...
  28. Athmer J, Fehr A, Grunewald M, Smith E, Denison M, Perlman S. In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins. MBio. 2017;8: pubmed publisher
    ..Furthermore, the use of in situ epitope tags could be used to determine novel nsp-nsp interactions in coronaviruses...
  29. Zhao Y, Zhao L, Ischenko I, Bao Q, Schwarz B, Nieß H, et al. Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer. Target Oncol. 2015;10:535-48 pubmed publisher
    ..SP cells, among which a highly significant difference in microRNA expression of miR-21 and miR-221 between SP and NSP cells was identified...
  30. An R, Tang Y, Chen L, Cai H, Lai D, Liu K, et al. Encephalitis is mediated by ROP18 of Toxoplasma gondii, a severe pathogen in AIDS patients. Proc Natl Acad Sci U S A. 2018;115:E5344-E5352 pubmed publisher
    ..mass spectrometry, we performed proteomic analysis of proteins that selectively bind to active ROP18 and identified RTN1-C, an endoplasmic reticulum (ER) protein that is preferentially expressed in the CNS...
  31. Nazari S, Noroozi M, Soori H, Noroozi A, Mehrabi Y, Hajebi A, et al. The effect of on-site and outreach-based needle and syringe programs in people who inject drugs in Kermanshah, Iran. Int J Drug Policy. 2016;27:127-31 pubmed publisher
    ..This study assessed the effect of facility-based (on-site services at drop-in centre) and outreach models of NSP on injection risk behaviours...
  32. Hu Z, Chen Z, Goei R, Wu W, Lim T. Magnetically recyclable Bi/Fe-based hierarchical nanostructures via self-assembly for environmental decontamination. Nanoscale. 2016;8:12736-46 pubmed publisher
    ..Compared to single-crystalline Bi2Fe4O9 (PS) and Bi2Fe4O9 clusters (NSP), BFO-M shows an excellent organic pollutant removal rate by virtue of its high adsorption capacity and catalytic ..
  33. McVeigh J, Hearne E, Bates G, Van Hout M. Community pharmacist experiences of providing needle and syringe programmes in Ireland. Res Social Adm Pharm. 2017;13:767-777 pubmed publisher
    ..accessible health providers in providing harm reduction support to drug users via needle and syringe programmes (NSP), provision of advice, HIV/Hepatitis testing and as referral mechanism to social, medical and treatment services...
  34. O Keefe D, Scott N, Aitken C, Dietze P. Longitudinal analysis of change in individual-level needle and syringe coverage amongst a cohort of people who inject drugs in Melbourne, Australia. Drug Alcohol Depend. 2017;176:7-13 pubmed publisher
    Needle and syringe program (NSP) coverage is often calculated at the individual level...
  35. Alberti M, la Cour M. NONSUPINE POSITIONING IN MACULAR HOLE SURGERY: A Noninferiority Randomized Clinical Trial. Retina. 2016;36:2072-2079 pubmed
    To determine whether nonsupine positioning (NSP) is noninferior to face-down positioning (FDP) in full-thickness macular hole (FTMH) surgery. This is a single-center, open-label, randomized controlled trial...
  36. Liszka Ł, Mrowiec S, Kusnierz K, Kajor M. Standardized grossing protocol is useful for the pathology reporting of malignant neoplasms other than adenocarcinomas treated with pancreaticoduodenectomy. Histol Histopathol. 2017;32:177-192 pubmed publisher
    ..were compared with corresponding data of a historical cohort of 19 cases examined using non-standardized protocol (NSP)...
  37. Salmasi A, Lee G, Patel N, Goyal R, Dinizo M, Kwon Y, et al. Off-Target Effect of Sildenafil on Postsurgical Erectile Dysfunction: Alternate Pathways and Localized Delivery System. J Sex Med. 2016;13:1834-1843 pubmed publisher
    ..Male rats underwent BCNI and were untreated (BCNI), immediately treated with application of empty NSPs (BCNI + NSP), NSPs containing sildenafil (Sild + NSP), or NSPs containing rolipram (Rol + NSP)...
  38. Arcila J, Weier S, Rose D. Changes in dietary fiber fractions and gut microbial fermentation properties of wheat bran after extrusion and bread making. Food Res Int. 2015;74:217-223 pubmed publisher
    The dietary fiber in wheat bran, principally non-starch polysaccharides (NSP), is mostly water-unextractable and is poorly utilized by human gut microbiota...
  39. Gschwandtner M, Kienzl P, Tajpara P, Schuster C, Stipek G, Buchberger M, et al. The Reticulum-Associated Protein RTN1A Specifically Identifies Human Dendritic Cells. J Invest Dermatol. 2018;138:1318-1327 pubmed publisher
    b>RTN1 is an endoplasmic reticulum-associated protein that was initially identified in neuronal tissues. Here we show that the main isoform RTN1A is a marker for dendritic cells...
  40. Gardiner P, Wikell C, Clifton S, Shearer J, Benjamin A, Peters S. Neutrophil maturation rate determines the effects of dipeptidyl peptidase 1 inhibition on neutrophil serine protease activity. Br J Pharmacol. 2016;173:2390-401 pubmed publisher
    ..The effects of neutrophil turnover rate on NSP activity following DPP1 inhibition was studied in a rat pharmacokinetic/pharmacodynamic model...
  41. Rossi M, Pasanen K, Kokko S, Alanko L, Heinonen O, Korpelainen R, et al. Low back and neck and shoulder pain in members and non-members of adolescents' sports clubs: the Finnish Health Promoting Sports Club (FHPSC) study. BMC Musculoskelet Disord. 2016;17:263 pubmed publisher
    ..of this study was to investigate the prevalence of self-reported low back pain (LBP) and neck and shoulder pain (NSP), and the related factors in members and non-members of adolescents' sports clubs...
  42. Montanhini Neto R, N Guetta E, Gady C, Francesch M, Preynat A. Combined effect of using near-infrared spectroscopy for nutritional evaluation of feed ingredients and non-starch polysaccharide carbohydrase complex on performance of broiler chickens. Anim Sci J. 2017;88:1979-1986 pubmed publisher
    ..for nutritional evaluation of feed ingredients and the addition of non-starch polysaccharide carbohydrase complex (NSP enzymes) on the growth performance of broilers fed diets produced with low-quality wheat and soybean meal...
  43. Emsen I. A Different Approach to the Reconstruction of Nasal Septum Perforations: Alar Winged Flap. J Craniofac Surg. 2015;26:e698-702 pubmed publisher
    ..Between 2010 and 2014, a total of 13 patients with medium-large NSP were treated with this approach. Of these 13 patients, 9 were male (69%) and 4 female (31%). Average age was 40...
  44. Ambadapadi S, Munuswamy Ramanujam G, Zheng D, Sullivan C, Dai E, Morshed S, et al. Reactive Center Loop (RCL) Peptides Derived from Serpins Display Independent Coagulation and Immune Modulating Activities. J Biol Chem. 2016;291:2874-87 pubmed publisher
    ..Myxomavirus Serp-1 inhibits thrombolytic and thrombotic proteases, whereas mammalian neuroserpin (NSP) inhibits only thrombolytic proteases...
  45. Abrahamczyk S, Kessler M, Hanley D, Karger D, Müller M, Knauer A, et al. Pollinator adaptation and the evolution of floral nectar sugar composition. J Evol Biol. 2017;30:112-127 pubmed publisher
    ..Here, we use a modelling approach to evaluate the hypothesis that nectar sucrose proportion (NSP) is an adaptation to pollinators...
  46. Hu J, Li J, Yue X, Wang J, Wang J, Liu J, et al. Targeting BCRP/ABCG2 by RNA interference enhances the chemotherapy sensitivity of human colon cancer side population cells. J Huazhong Univ Sci Technolog Med Sci. 2017;37:231-236 pubmed publisher
    ..Compared to non-SP (NSP) cells, SP colon cancer cells were more tumorigenic in vivo and exhibited more invasive characteristics and a ..
  47. Li W, Asakawa T, Han S, Xiao B, Namba H, Lu C, et al. Neuroprotective effect of neuroserpin in non-tPA-induced intracerebral hemorrhage mouse models. BMC Neurol. 2017;17:196 pubmed publisher
    The neuroprotective effects of neuroserpin (NSP) have been well documented in both patients and animal models with cerebral ischemia; however, have never been investigated in hemorrhagic stroke...
  48. Gupta D. Strategy and way forward for TB elimination. Indian J Tuberc. 2018;65:4-5 pubmed publisher
    India's National Strategic Plan (NSP) for TB Elimination 2017-25 looks ambitious in terms of targets of TB notification aiming to reach 35 lakh TB patients annually, i.e. double that of current status...
  49. Topping D, Clifton P. Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev. 2001;81:1031-64 pubmed
    ..Human colonic bacteria ferment RS and nonstarch polysaccharides (NSP; major components of dietary fiber) to short-chain fatty acids (SCFA), mainly acetate, propionate, and butyrate...
  50. Balakrishnan S, Manikantan J, Sreenivas A, Jayasankar S, Sunilkumar M, Rakesh P, et al. Social inclusion: An effort to end loss-to-treatment follow-up in tuberculosis. Indian J Tuberc. 2015;62:230-4 pubmed publisher
    ..positive patients as never put on treatment (Initial lost to follow up - ILFU) and 5% of the new smear positive [NSP] Pulmonary TB patients as lost to follow up [LFU] during treatment...
  51. Otiashvili D, Latypov A, Kirtadze I, Ibragimov U, Zule W. Drug preparation, injection, and sharing practices in Tajikistan: a qualitative study in Kulob and Khorog. Subst Abuse Treat Prev Policy. 2016;11:21 pubmed publisher
    ..focus group discussions (6 per city) with 100 people who inject drugs recruited through needle and syringe program (NSP) outreach in May 2014...
  52. Iversen J, Dertadian G, Geddes L, Maher L. High risk injecting behaviour among people who inject pharmaceutical opioids in Australia. Int J Drug Policy. 2017;42:1-6 pubmed publisher
    ..The Australian NSP Survey (ANSPS), conducted annually at ∼50 NSP services across Australia, consists of a brief self-administered ..
  53. Wasonga C, Inoue S, Rumberia C, Michuki G, Kimotho J, Ongus J, et al. Genetic divergence of Chikungunya virus plaque variants from the Comoros Island (2005). Virus Genes. 2015;51:323-8 pubmed publisher
    ..of the CHIKV plaque variants and S27 African prototype strain, showed 30 AA changes in the non-structural proteins (nsP) and 22 AA changes in the structural proteins. Between L2 and S7, only two AAs differences were observed...
  54. Ma J, Adler L, Srzednicki G, Arcot J. Quantitative determination of non-starch polysaccharides in foods using Gas Chromatography with flame ionization detection. Food Chem. 2017;220:100-107 pubmed publisher
    ..Sample preparation involved enzymatic removal of starch and acid hydrolysis of the NSP to their constituent sugars...
  55. Fredriksson L, Stevenson T, Su E, Ragsdale M, Moore S, Craciun S, et al. Identification of a neurovascular signaling pathway regulating seizures in mice. Ann Clin Transl Neurol. 2015;2:722-38 pubmed publisher
    ..was used in genetically modified mice, including mice deficient in tPA (tPA (-/-) ), its inhibitor neuroserpin (Nsp (-/-) ), or both (Nsp:tPA (-/-) ), and in mice conditionally deficient in the platelet-derived growth factor ..
  56. Elnekave E, Van Maanen K, Shilo H, Gelman B, Storm N, Abed El Khaliq M, et al. Prevalence and risk factors for foot and mouth disease infection in cattle in Israel. Prev Vet Med. 2016;130:51-9 pubmed publisher
    ..endemic among cattle and to determine the sero-prevalence of antibodies directed against non-structural proteins (NSP) of FMD virus. Additionally we aimed to determine the risk factors for such sero-positivity...
  57. Hayashi Miyamoto M, Murakami T, Minami Fukuda F, Tsuchiaka S, Kishimoto M, Sano K, et al. Diversity in VP3, NSP3, and NSP4 of rotavirus B detected from Japanese cattle. Infect Genet Evol. 2017;49:97-103 pubmed publisher
    ..Currently, a few sequences of viral protein (VP)1, 2, 4, 6, and 7 and nonstructural protein (NSP)1, 2, and 5 of bovine RVB are available in the DDBJ/EMBL/GenBank databases, and none have been reported for VP3, ..
  58. Zamri E, Moy F, Hoe V. Association of psychological distress and work psychosocial factors with self-reported musculoskeletal pain among secondary school teachers in Malaysia. PLoS ONE. 2017;12:e0172195 pubmed publisher
    ..To assess the prevalence of self-reported low back pain (LBP), and neck and/or shoulder pain (NSP) among secondary school teachers; and to evaluate the association of LBP and NSP with psychological distress and ..
  59. Fernandes R, Cary M, Duarte G, Jesus G, Alarcão J, Torre C, et al. Effectiveness of needle and syringe Programmes in people who inject drugs - An overview of systematic reviews. BMC Public Health. 2017;17:309 pubmed publisher
    Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID)...
  60. Iwahashi J, Hamada N. Human reticulon 1-A and 1-B interact with a medium chain of the AP-2 adaptor complex. Cell Mol Biol (Noisy-le-grand). 2003;49 Online Pub:OL467-71 pubmed
    Human reticulon family gene 1 (RTN1) is expressed predominantly in neuroendocrine tissues, and produces three proteins termed RTN1-A, RTN1-B, and RTN1-C...
  61. Chen Y, Savinov S, Mielech A, Cao T, Baker S, Mesecar A. X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions. J Biol Chem. 2015;290:25293-306 pubmed publisher
    ..Non-structural protein 3 (nsp3) is the largest nsp in the coronavirus genome, and it contains multiple functional domains that are required for coronavirus ..
  62. Boynueğri S, Cayönü M, Tuna E, Kurukahvecioglu S, Ozcan K, Turkay B, et al. The Effect of Nasal Septal Perforation and its Treatment on Objective Sleep and Breathing Parameters. Med Sci Monit. 2016;22:501-7 pubmed
    BACKGROUND Nasal septal perforation (NSP) may alter nasal airflow patterns and physiology...
  63. Jones N, Fournier J, Stone L. Neural correlates of autobiographical problem-solving deficits associated with rumination in depression. J Affect Disord. 2017;218:210-216 pubmed publisher
    ..and 18 never-depressed adults) ranging in rumination engaged in APS and negative self-referential processing (NSP) of negative trait adjectives during fMRI...
  64. Casey A, Chen S, Novick P, Ferro Novick S, Wente S. Nuclear pore complex integrity requires Lnp1, a regulator of cortical endoplasmic reticulum. Mol Biol Cell. 2015;26:2833-44 pubmed publisher
    ..Both Lnp1 and Sey1 physically associate with other ER components that have established NPC roles, including Rtn1, Yop1, Pom33, and Per33...
  65. Wu J, Yang C, Wu Y, Wang P, Tseng F. Continuous affinity-gradient nano-stationary phase served as a column for reversed-phase electrochromatography and matrix carrier in time-of-flight mass spectrometry for protein analysis. Anal Chim Acta. 2015;889:166-71 pubmed publisher
    This study developed an affinity-gradient nano-stationary phase (AG-NSP) for protein analysis using nanofluidic capillary electrochromatography (nano-CEC) conjugated with matrix assisted laser desorption ionization (MALDI) time-of-flight ..
  66. Rascón Castelo E, Burgara Estrella A, Reséndiz Sandoval M, Hernández Lugo A, Hernández J. Immune Response of Multiparous Hyper-Immunized Sows against Peptides from Non-Structural and Structural Proteins of PRRSV. Vaccines (Basel). 2015;3:973-87 pubmed publisher
    ..and cellular responses of commercial multiparous and hyper-immunized sows against peptides from non-structural (nsp) and structural proteins of porcine reproductive and respiratory syndrome virus (PRRSV)...
  67. Daly F, Spicer N, Willan S. Sexual rights but not the right to health? Lesbian and bisexual women in South Africa's National Strategic Plans on HIV and STIs. Reprod Health Matters. 2016;24:185-94 pubmed publisher
    ..Plan for South Africa 2007-2011 and why and how these concerns were deprioritised in the National Strategic Plan (NSP) on HIV, STIs and TB 2012-2016...
  68. Kuruba B, Buvani A, Veluthambi K. Yellow mosaic symptom caused by the nuclear shuttle protein gene of mungbean yellow mosaic virus is associated with single-stranded DNA accumulation and mesophyll spread of the virus. Acta Virol. 2016;60:224-33 pubmed
    ..Swapping of KA27 DNA-B with the nuclear shuttle protein gene (NSP) of KA22 DNA-B (KA27xKA22 NSP) caused yellow mosaic symptom in blackgram, suggesting that KA22 NSP is the ..
  69. Mukherjee T, Pillai V, Ali S, Altice F, Kamarulzaman A, Wickersham J. Evaluation of a hepatitis C education intervention with clients enrolled in methadone maintenance and needle/syringe programs in Malaysia. Int J Drug Policy. 2017;47:144-152 pubmed publisher
    ..We recruited 176 clients from methadone maintenance treatment (MMT: N=110) and needle/syringe programs (NSP: N=66) between November 2015 and August 2016...
  70. Yu T, Ma B, Wang J. Identification of linear B-cell epitopes on goose parvovirus non-structural protein. Vet Immunol Immunopathol. 2016;179:85-8 pubmed publisher
    ..unknown for the localization and immunological characteristics of B-cell epitopes on GPV non-structural protein (NSP)...
  71. Deng X, Baker S. An "Old" protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses. Virology. 2018;517:157-163 pubmed publisher
    ..Coronavirus EndoU is encoded within the sequence of nonstructural protein (nsp) 15, which was initially identified as a component of the viral replication complex...
  72. Hallman D, Mathiassen S, Heiden M, Gupta N, Jørgensen M, Holtermann A. Temporal patterns of sitting at work are associated with neck-shoulder pain in blue-collar workers: a cross-sectional analysis of accelerometer data in the DPHACTO study. Int Arch Occup Environ Health. 2016;89:823-33 pubmed publisher
    ..work and during leisure-time, assessed using accelerometry, are associated with intense neck-shoulder pain (NSP) in blue-collar workers. The population consisted of 659 Danish blue-collar workers...
  73. Rokyta R, Holub M, Matejovic M, Hanzlikova J, Helcl M, Novak I, et al. Continuous venovenous hemofiltration: effects on monocyte and lymphocyte immunophenotype in critically ill patients. Int J Artif Organs. 2002;25:1066-73 pubmed
    ..24 septic (SP) and 10 non-septic (NSP) medical ICU patients with acute renal failure were studied prospectively. The ultrafiltration rate was 20-30 ml...
  74. Kachhap S, Faith D, Qian D, Shabbeer S, Galloway N, Pili R, et al. The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin. PLoS ONE. 2007;2:e844 pubmed
    ..This novel finding of NDRG1 as a recycling protein involved with recycling of E-cadherin will aid in understanding NDRG1 role as a metastasis suppressor protein. ..
  75. Chen L, Wan L, Du J, Shen Y. Identification of MANF as a protein interacting with RTN1-C. Acta Biochim Biophys Sin (Shanghai). 2015;47:91-7 pubmed publisher
    ..Such evidence is particularly associated with the RTN1-C family members...
  76. Deryabina A, El Sadr W. Uptake of needle and syringe program services in the Kyrgyz Republic: Key barriers and facilitators. Drug Alcohol Depend. 2017;179:180-186 pubmed publisher
    ..In 2015, we conducted an assessment at 19 NSP sites in six cities to identify barriers and facilitators that affect PWID uptake of NSP services in Kyrgyzstan...
  77. Mahlangu P, Vearey J, Thomas L, Goudge J. Implementing a multi-sectoral response to HIV: a case study of AIDS councils in the Mpumalanga Province, South Africa. Glob Health Action. 2017;10:1387411 pubmed publisher
    ..In March 2017, the South African National AIDS Council (SANAC) launched the latest 5 year National Strategic Plan (NSP) to address HIV, sexually transmitted infections and tuberculosis...
  78. Sayama T, Tanabata T, Saruta M, Yamada T, Anai T, Kaga A, et al. Confirmation of the pleiotropic control of leaflet shape and number of seeds per pod by the Ln gene in induced soybean mutants. Breed Sci. 2017;67:363-369 pubmed publisher
    ..The recessive allele ln has also been considered to increase the number of seeds per pod (NSP) and has the potential to improve yield...
  79. Hallman D, Rasmussen C, Jørgensen M, Holtermann A. Time course of neck-shoulder pain among workers: A longitudinal latent class growth analysis. Scand J Work Environ Health. 2018;44:47-57 pubmed publisher
    Objectives The aims of this study were to (i) identify trajectories of neck-shoulder pain (NSP) over one year in an occupational population and (ii) determine whether these trajectories are predicted by NSP characteristics as well as ..
  80. Roebroek A, van de Velde H, Van Bokhoven A, Broers J, Ramaekers F, Van de Ven W. Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product. J Biol Chem. 1993;268:13439-47 pubmed
    ..to belong to a previously unknown gene with a neuroendocrine-specific expression pattern, tentatively designated NSP gene. NSP transcription appeared to result in mRNAs of 3.4 and 1.8 kilobases (kb)...
  81. Mannan A, Boehm J, Sauter S, Rauber A, Byrne P, Neesen J, et al. Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with Reticulon 1 an endoplasmic reticulum protein. Neurogenetics. 2006;7:93-103 pubmed
    ..Using spastin as bait, we identified reticulon 1 (RTN1) and reticulon 3 (RTN3) as potential spastin interacting proteins...
  82. Nepravishta R, Polizio F, Paci M, Melino S. A metal-binding site in the RTN1-C protein: new perspectives on the physiological role of a neuronal protein. Metallomics. 2012;4:480-7 pubmed publisher
    b>Reticulon 1-C (RTN1-C) is an ER-associated neuronal protein characterized by horse-shoe-like topology with two transmembrane helices and the N- and C-terminal regions which are supposed in the cytosolic side of ER...
  83. Zule W, Cross H, Stover J, Pretorius C. Are major reductions in new HIV infections possible with people who inject drugs? The case for low dead-space syringes in highly affected countries. Int J Drug Policy. 2013;24:1-7 pubmed publisher
    ..waiting for them to be completed, we argue for an approach similar to that used with needle and syringe programs (NSP), which were promoted and implemented before being tested more rigorously...
  84. Rahaman J, Siltberg Liberles J. Avoiding Regions Symptomatic of Conformational and Functional Flexibility to Identify Antiviral Targets in Current and Future Coronaviruses. Genome Biol Evol. 2016;8:3471-3484 pubmed publisher
    ..The identified sequence motif is found within the nonstructural protein (NSP) 12 and constitutes an antiviral target potentially effective against the present day and future coronaviruses...
  85. Babu P, Kumar P, Mohan A, Kumar B, Sarma P. Novel mutations in the exon 5, intron 2 and 3' UTR regions of IL-12B gene were observed in clinically proven tuberculosis patients of south India. Cytokine. 2017;99:50-58 pubmed publisher
    ..the present study IL-12B gene status was evaluated in 50 new sputum smear-positive pulmonary tuberculosis patients (NSP-PTB) as identified by Ziehl-Nielsen (ZN) staining and 50 apparently healthy control subjects (HCS) who were sputum ..
  86. Hornero R, Kheirandish Gozal L, Gutiérrez Tobal G, Philby M, Alonso Alvarez M, Alvarez D, et al. Nocturnal Oximetry-based Evaluation of Habitually Snoring Children. Am J Respir Crit Care Med. 2017;: pubmed publisher
    ..Thus, nocturnal oximetry may enable a simple and effective diagnostic alternative to NPSG leading to more timely interventions and potentially improved outcomes. ..
  87. Cao S, Cai X, Tan M, Sun F, Wang Y, Shang Y, et al. Serodiagnosis, targeting nonstructural protein 4, of porcine reproductive and respiratory syndrome virus. Arch Virol. 2018;163:411-418 pubmed publisher
    ..Non-structural protein (NSP) 4 is essential to the PRRSV life cycle and contains B-cell epitopes...
  88. Wang J, Qiu Y, Wang X, Yue Z, Yang X, Chen X, et al. Insights into the species-specific metabolic engineering of glucosinolates in radish (Raphanus sativus L.) based on comparative genomic analysis. Sci Rep. 2017;7:16040 pubmed publisher
    ..of the expression of a putative non-functional epithiospecifier (ESP) gene in any tissue and the nitrile-specifier (NSP) gene in roots facilitates the accumulation of distinctive beneficial isothiocyanates in R. sativus...
  89. van de Velde H, Senden N, Roskams T, Broers J, Ramaekers F, Roebroek A, et al. NSP-encoded reticulons are neuroendocrine markers of a novel category in human lung cancer diagnosis. Cancer Res. 1994;54:4769-76 pubmed
    The NSP gene was recently shown to constitute the prototype of a novel gene family, to be selectively transcribed in neural and endocrine cells, and to encode three overlapping proteins, NSP-A, NSP-B, and NSP-C...
  90. Di Sano F, Fazi B, Citro G, Lovat P, Cesareni G, Piacentini M. Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells. Cancer Res. 2003;63:3860-5 pubmed
    ..These findings demonstrate a novel p53-independent pathway of apoptosis regulated by Golgi/endoplasmic reticulum protein interactions, which is relevant for cancer combined therapy. ..
  91. Zambrano Zaragoza M, Quintanar Guerrero D, del Real A, Piñón Segundo E, Zambrano Zaragoza J. The release kinetics of ?-carotene nanocapsules/xanthan gum coating and quality changes in fresh-cut melon (cantaloupe). Carbohydr Polym. 2017;157:1874-1882 pubmed publisher
    ..xanthan gum alone (XG), xanthan gum combined with nanocapsules (Ncs/XG), xanthan gum combined with nanospheres (Nsp/XG), nanocapsules (Ncs), and nanospheres (Nsp), all of which were compared to untreated fresh-cut melon in order to ..
  92. Wu Q, Kamphuis C, Duo L, Luo J, Chen Y, Richardus J. Coverage of harm reduction services and HIV infection: a multilevel analysis of five Chinese cities. Harm Reduct J. 2017;14:10 pubmed publisher
    ..It entails services for condom promotion, a needle and syringe program (NSP), and methadone maintenance treatment (MMT)...