RPS7

Summary

Gene Symbol: RPS7
Description: ribosomal protein S7
Alias: DBA8, 40S ribosomal protein S7
Species: human

Top Publications

  1. doi Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase
    Olesya O Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Mol Microbiol 83:640-53. 2012
  2. pmc Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation
    Ming Gao
    Department of Pathophysiology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, PR China
    Nucleic Acids Res 41:5210-22. 2013
  3. pmc The small-subunit processome is a ribosome assembly intermediate
    Kara A Bernstein
    Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, C114 SHM, 333 Cedar St, New Haven, CT 06520 8024, USA
    Eukaryot Cell 3:1619-26. 2004
  4. ncbi [The internal control role of ribosomal protein S7 in the defense of Anopheles dirus against Plasmodium infection]
    Wen Yue Xu
    Department of Pathogenic Biology, Third Military Medical University, Chongqing, 400038
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 21:264-7. 2003
  5. ncbi Plastid genome characterisation in Brassica and Brassicaceae using a new set of nine SSRs
    M L Flannery
    Department of Botany, School of Natural Sciences, Trinity College, University of Dublin, Dublin, D2, Ireland
    Theor Appl Genet 113:1221-31. 2006
  6. ncbi Chloroplast transformation in oilseed rape
    Bing Kai Hou
    Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, PR China
    Transgenic Res 12:111-4. 2003
  7. ncbi [Production of Brassica olereceae (+Arabidopsis thaliana) and Brassica napus cell lines resistant to spectinomycin/streptomycin as a result of plastome genetic transformation]
    I O Nitovs'ka
    Tsitol Genet 40:3-10. 2006
  8. doi Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia
    Madoka Kuramitsu
    Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan
    Blood 119:2376-84. 2012
  9. pmc Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia
    Hanna T Gazda
    Division of Genetics and Program in Genomics, The Manton Center for Orphan Disease Research, Children s Hospital Boston, 3 BlackfanCircle, Boston, MA 02115, USA
    Hum Mutat 33:1037-44. 2012
  10. doi A novel mutation of ribosomal protein S10 gene in a Japanese patient with diamond-Blackfan anemia
    Makoto Yazaki
    Department of Pediatrics, Nagoya City East Medical Center Moriyama Hospital, Nagoya, Japan
    J Pediatr Hematol Oncol 34:293-5. 2012

Research Grants

  1. TRANSFER OF ORGANELLE GENES TO THE NUCLEUS
    Jeffrey Palmer; Fiscal Year: 2000
  2. Regulation of p53 tumor suppressor protein
    Carol Prives; Fiscal Year: 2010

Scientific Experts

Detail Information

Publications69

  1. doi Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase
    Olesya O Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Mol Microbiol 83:640-53. 2012
    ..A different role of the Rps7 paralogues in vivo is supported by the observation that the deletion of Rps7A but not Rps7B is sensitive to ..
  2. pmc Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation
    Ming Gao
    Department of Pathophysiology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, PR China
    Nucleic Acids Res 41:5210-22. 2013
    ..Our findings thus identify a novel function of S7 in control of GADD45α stabilization under both basal and stress conditions and its significance in mediating arsenite-induced cellular stress...
  3. pmc The small-subunit processome is a ribosome assembly intermediate
    Kara A Bernstein
    Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, C114 SHM, 333 Cedar St, New Haven, CT 06520 8024, USA
    Eukaryot Cell 3:1619-26. 2004
    ..we characterize 12 additional protein components, including five small-ribosomal-subunit proteins (Rps4, Rps6, Rps7, Rps9, and Rps14) that had previously been copurified...
  4. ncbi [The internal control role of ribosomal protein S7 in the defense of Anopheles dirus against Plasmodium infection]
    Wen Yue Xu
    Department of Pathogenic Biology, Third Military Medical University, Chongqing, 400038
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 21:264-7. 2003
    To investigate the role of ribosomal protein S7 (rpS7) in the defense of Anopheles dirus against infection.
  5. ncbi Plastid genome characterisation in Brassica and Brassicaceae using a new set of nine SSRs
    M L Flannery
    Department of Botany, School of Natural Sciences, Trinity College, University of Dublin, Dublin, D2, Ireland
    Theor Appl Genet 113:1221-31. 2006
    ..oleracea, B. rapa and in related genera Arabidopsis, Camelina, Raphanus and Sinapis. Eleven gene regions (ndhB-rps7 spacer, rbcL-accD spacer, rpl16 intron, rps16 intron, atpB-rbcL spacer, trnE-trnT spacer, trnL intron, trnL-trnF ..
  6. ncbi Chloroplast transformation in oilseed rape
    Bing Kai Hou
    Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, PR China
    Transgenic Res 12:111-4. 2003
    ..The two cassettes are sited between the rps7 and ndhB targeting fragments...
  7. ncbi [Production of Brassica olereceae (+Arabidopsis thaliana) and Brassica napus cell lines resistant to spectinomycin/streptomycin as a result of plastome genetic transformation]
    I O Nitovs'ka
    Tsitol Genet 40:3-10. 2006
    ..carried resistance (aadA) gene flanked by rapeseed plastid DNA sequences to target its insertion between the trnV-rps7 fragments...
  8. doi Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia
    Madoka Kuramitsu
    Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan
    Blood 119:2376-84. 2012
    ..To identify new mutations, we investigated large deletions in the RP genes RPL5, RPL11, RPL35A, RPS7, RPS10, RPS17, RPS19, RPS24, and RPS26...
  9. pmc Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia
    Hanna T Gazda
    Division of Genetics and Program in Genomics, The Manton Center for Orphan Disease Research, Children s Hospital Boston, 3 BlackfanCircle, Boston, MA 02115, USA
    Hum Mutat 33:1037-44. 2012
    ..We also found a deletion in RPL19 and missense mutations in RPL3 and RPL23A, which may be variants of unknown significance. Together with RPL5, RPL11, and RPS7, RPL26 is the fourth RP regulating p53 activity that is linked to DBA.
  10. doi A novel mutation of ribosomal protein S10 gene in a Japanese patient with diamond-Blackfan anemia
    Makoto Yazaki
    Department of Pediatrics, Nagoya City East Medical Center Moriyama Hospital, Nagoya, Japan
    J Pediatr Hematol Oncol 34:293-5. 2012
    ..DBA is associated with mutations in the ribosomal protein (RP) genes, RPS19, RPS24, RPS17, RPL35A, RPL5, RPL11, and RPS7. Recently, 5 and 12 patients with mutations in RPS10 and RPS26, respectively, were identified in a cohort of 117 ..
  11. doi A new function of ROD1 in nonsense-mediated mRNA decay
    T F Brazão
    Department of Cell Biology and Genetics, Erasmus MC, Rotterdam, The Netherlands
    FEBS Lett 586:1101-10. 2012
    ..Finally, we show through RIP-seq that ROD1 and UPF1 associate with a significant number of common transcripts...
  12. pmc Comparative Evolution of S7 Intron 1 and Ribosomal Internal Transcribed Spacer in Coilia nasus (Clupeiformes: Engraulidae)
    Dong Liu
    College of Fisheries and Life Science, Shanghai Ocean University, Shanghai, 201306, China E Mails D L H Y G J Q Y
    Int J Mol Sci 13:3085-100. 2012
    ..Here we analyze and compare the nucleotide sequences between single-copy ribosomal protein S7 gene intron 1 (rpS7) and multiple-copy ribosomal internal transcribed spacer 1 (ITS1) in this species to compare the phylogenetic ..
  13. pmc Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes
    Dawn E Watkins-Chow
    National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 9:e1003094. 2013
    ..Here we report the first two mouse mutations (Rps7(Mtu) and Rps7(Zma)) of ribosomal protein S7 (Rps7), a gene that has been implicated in Diamond-Blackfan anemia...
  14. ncbi [Analysis of mutations of ribosomal protein genes in 21 cases of Diamond-Blackfan anemia]
    Yu Mei Chen
    Center for Diagnosis and Therapy of Childhood Blood Diseases, Blood Disease Hospital and Institute of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:1414-8. 2012
    ..were screened by PCR for mutations in the nine known genes associated with DBA: RPS19, RPS24, RPS17, RPL5, RPL11, RPS7, RPL35a, RPS10 and RPS26. The results found that 8 patients (38...
  15. pmc Complete sequence of 'divided' rps12 (r-protein S12) and rps7 (r-protein S7) gene in soybean chloroplast DNA
    J M von Allmen
    Nucleic Acids Res 15:2387. 1987
  16. ncbi Immunochemical accessibility of ribosomal protein S4 in the 30 S ribosome. The interaction of S4 with S5 and S12
    D A Winkelmann
    J Mol Biol 165:357-74. 1983
    ..The effect of S5 and S12 on S4 accessibility is consistent with data from a variety of other approaches, suggesting that these proteins form a structural and functional domain in the small ribosomal subunit...
  17. pmc Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress
    Sladana Bursac
    Department of Molecular Medicine and Biotechnology, School of Medicine, University of Rijeka, 51000 Rijeka, Croatia
    Proc Natl Acad Sci U S A 109:20467-72. 2012
    ..These findings may have important implications with respect to understanding the pathogenesis of diseases caused by impaired ribosome biogenesis...
  18. ncbi An alloplasmic male-sterile line of Brassica oleracea harboring the mitochondria from Diplotaxis muralis expresses a novel chimeric open reading frame, orf72
    Tomotaka Shinada
    Laboratory of Plant Breeding and Genetics, Graduate School of Agricultural Science, Tohoku University, 1 1 Tsutsumidori Amamiyamachi, Aoba ku, Sendai, 981 8555 Japan
    Plant Cell Physiol 47:549-53. 2006
    ..It was located downstream of normal rps7 and contained part of atp9 (atp9-b). It was expressed specifically on the nuclear background of CMS B...
  19. doi Subdivision of molecularly-classified groups by new gene signatures in breast cancer patients
    Athanasios Armakolas
    Laboratory of Experimental Physiology, Medical School, National and Kapodestrian University of Athens, Athens 11527, Greece
    Oncol Rep 28:2255-63. 2012
    ..A newly established classifier (ENY2, USP38, RPS7, Osbpl-1 and ETF1) indicated a statistically significant association with HER2 subtype patients, ..
  20. doi Potential role of tRNAs in wheat and Lolium mitochondrial rps7 transcript processing
    Evan Byers
    Biology Department, University of Ottawa, 30 Marie Curie, Ottawa, ON K1N 6N5, Canada
    Genome 55:615-21. 2012
    ..In another grass, Lolium multiflorum Lam., rps7 displays transcripts of 1.3 and 0...
  21. doi Impact of genomic environment on mitochondrial rps7 mRNA features in grasses
    Evan Byers
    Biology Department, University of Ottawa, 30 Marie Curie, Ottawa, Canada
    Mol Genet Genomics 284:207-16. 2010
    ..generation of mature mRNAs, and to this end we have determined the termini of mitochondrial S7 ribosomal protein (rps7) mRNAs from selected grasses, using circularized-RT-PCR...
  22. pmc Ribosomal protein S19 and S24 insufficiency cause distinct cell cycle defects in Diamond-Blackfan anemia
    Jitendra Badhai
    Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    Biochim Biophys Acta 1792:1036-42. 2009
    ..a predisposition for malignant disease and heterozygous mutations in either of the ribosomal protein (RP) genes RPS7, RPS17, RPS19, RPS24, RPL5, RPL11 and RPL35a...
  23. doi RNA editing in six mitochondrial ribosomal protein genes of Didymium iridis
    Peter G Hendrickson
    Immunology Department, Children s Memorial Research Center, Chicago, IL 60614, USA
    Curr Genet 56:203-13. 2010
    ..Six functional transcripts were verified for the following ribosomal protein genes: rpS12, rpS7, rpL2, rpS19, rpS3, and rpL16...
  24. pmc Yeast strains with N-terminally truncated ribosomal protein S5: implications for the evolution, structure and function of the Rps5/Rps7 proteins
    Thomas Lumsden
    Center for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH 44115, USA
    Nucleic Acids Res 38:1261-72. 2010
    Ribosomal protein (rp)S5 belongs to the family of the highly conserved rp's that contains rpS7 from prokaryotes and rpS5 from eukaryotes...
  25. pmc Quantitative TaqMan real-time PCR assays for gene expression normalisation in feline tissues
    Yvonne Kessler
    University of Zurich, Switzerland
    BMC Mol Biol 10:106. 2009
    ....
  26. doi The position of gnetales among seed plants: overcoming pitfalls of chloroplast phylogenomics
    Bojian Zhong
    School of Life Sciences, Fudan University, Shanghai, China
    Mol Biol Evol 27:2855-63. 2010
    ..another analysis of partial genome data with dense taxon sampling of conifers showed that, in psbC, rpl2, and rps7 proteins, there are many parallel amino acid substitutions between the lineages leading to Gnetales and to ..
  27. pmc Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia
    Leana Doherty
    Division of Genetics and Program in Genomics, The Manton Center for Orphan Disease Research, Children s Hospital Boston, Boston, MA 02115, USA
    Am J Hum Genet 86:222-8. 2010
    ..been associated with mutations in seven ribosomal protein (RP) genes, RPS19, RPS24, RPS17, RPL35A, RPL5, RPL11, and RPS7, in about 43% of patients...
  28. doi Disorders of sex development and Diamond-Blackfan anemia: is there an association?
    Julia Hoefele
    Pediatric Nephrology, University Children s Hospital, Ludwig Maximilian s University, Dr von Haunersches Kinderspital, Lindwurmstrasse 4, 80337, Munich, Germany
    Pediatr Nephrol 25:1255-61. 2010
    ..More recently, mutations in other ribosomal protein genes, namely RPS7, RPS15, RPS24, RPS17, RPS27A, RPL35a, RPL36, RPL11, and RPL5, have also been found in patients with DBA...
  29. pmc Quantitative analysis of replication and tropisms of Dengue virus type 2 in Aedes albopictus
    Meichun Zhang
    Department of Parasitology, Zhongshan School of Medicine, Sun Yat Sen University, Guangzhou, People s Republic of China
    Am J Trop Med Hyg 83:700-7. 2010
    ..Subsequent Western blotting of DENV-2 E protein had similar results. Using ribosomal protein 7 (rpS7) as an internal control, we found that, in salivary gland, brain, fat body, and midgut, the average DENV-2 RNA ..
  30. ncbi The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25
    T Annilo
    Institute of Molecular and Cell Biology, Tartu University, Estonian Biocentre, Estonia
    Gene 165:297-302. 1995
    ..Human S7 (hS7) is identical to rat S7 (rS7) and exhibits significant similarity with the X. laevis, insect and plant homologs. We have used fluorescence in situ hybridization (FISH) to localize S7 to chromosome 2p25...
  31. ncbi Heteroplasmy and expression of mitochondrial genes in alloplasmic and euplasmic wheat
    Kanako Kawaura
    Kihara Institute for Biological Research, Yokohama City University, Japan
    Genes Genet Syst 86:249-55. 2011
    ..The atp4 gene (formerly called orf25) of Aegilops crassa (CR) harbors the promoter sequence of the rps7 gene from common wheat (Triticum aestivum cv. Chinese Spring, CS)...
  32. pmc Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress
    Xiao Xin Sun
    Department of Molecular and Medical Genetics, School of Medicine and the OHSU Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Biol Chem 286:22730-41. 2011
    ..Altogether, our results reveal that S27a plays a non-redundant role in mediating p53 activation in response to ribosomal stress via interplaying with MDM2...
  33. doi Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafish
    Juan Duan
    Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of Chinese Academy of Sciences, Shanghai, China
    Int J Biochem Cell Biol 43:1218-27. 2011
    ..The small ribosomal subunits RPS7, has been reported to modulate the mdm2-p53 interaction...
  34. pmc Untangling the phenotypic heterogeneity of Diamond Blackfan anemia
    Jason E Farrar
    Kimmel Comprehensive Cancer Center, Department of Oncology, Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    Semin Hematol 48:124-35. 2011
    ..encoding both large (RPL) and small (RPS) ribosomal subunit proteins, including mutations of RPL5, RPL11, RPL35A, RPS7, RPS10, RPS17, RPS19, RPS24, and RPS26 in 50% to 60% of affected patients...
  35. doi Expression of interferon gamma in the brain of cats with natural Borna disease virus infection
    Jonas Johansson Wensman
    Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences SLU, P O Box 7028, SE 75007 Uppsala, Sweden
    Vet Immunol Immunopathol 141:162-7. 2011
    ..The IFN-γ expression was normalised against the expression of three reference genes (HPRT, RPS7, YWHAZ)...
  36. pmc Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach
    Becky Pinjou Tsai
    Department of Microbiology and Molecular Genetics School of Medicine, University of California, Irvine, CA 92697 4025, USA
    Mol Cell Proteomics 10:M110.007385. 2011
    ..initiation factors (eIF4A-1, eIF-2A, and eIF3g), and ribosomal subunits with known noncanonical actions (RPS19, RPS7, and RPL26)...
  37. ncbi Construction of high sensitive detection system for endocrine disruptors with yeast n-alkane-assimilating Yarrowia lipolytica
    Eun Min Cho
    Seoul Center, Korea Basic Science Institute, Seoul 136 713, Korea
    J Microbiol Biotechnol 20:1563-70. 2010
    ..detection system for endocrine disruptors, we have compared the activity of promoters with the ALK1, ICL1, RPS7 and TEF1 for heterologous gene in Yarrowia lipolytica...
  38. doi SRY interacts with ribosomal proteins S7 and L13a in nuclear speckles
    Youichi Sato
    Department of Human Genetics and Public Health, Institute of Health Biosciences, Graduate School of Medicine, The University of Tokushima, Tokushima, Japan
    Cell Biol Int 35:449-52. 2011
    ..We found two ribosomal proteins, RPS7 (ribosomal protein S7) and RPL13a (ribosomal protein L13a) that interact with the HMG (high-mobility group) box ..
  39. pmc Ribosomal protein S7 is both a regulator and a substrate of MDM2
    Yan Zhu
    Department of Biological Sciences, Columbia University, New York, NY 10027, USA
    Mol Cell 35:316-26. 2009
    ..This indicates that MDM2 ubiquitination of S7 is involved in sustaining the p53 response. Thus, S7 functions as both effector and affector of MDM2 to ensure a proper cellular response to different stress signals...
  40. pmc Proteomics of rat prostate lobes treated with 2-N-hydroxylamino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 5alpha-dihydrotestosterone, individually and in combination
    Telih Boyiri
    Department of Biochemistry and Molecular Biology and Penn State Cancer Institute, Penn State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    Int J Oncol 35:559-67. 2009
    ..spots contained single proteins; including, phospholipase Calpha (PLP-Calpha), Rab7, SAR1a, ribosomal protein S7 (RPS7), and nucleoside diphosphate kinase (NDPK)...
  41. ncbi Photoperiod-sensitive cytoplasmic male sterility in wheat: nuclear-mitochondrial incompatibility results in differential processing of the mitochondrial orf25 gene
    Y Ogihara
    Kihara Institute for Biological Research, Yokohama City University, Japan
    Curr Genet 36:354-62. 1999
    ..wheat (AE-orf25) was determined, and we found that the upstream region of CR-orf25 had been replaced by that of rps7 of common wheat (AE-rps7) through recombination. A novel open reading frame (orf48) is present upstream of CR-orf25...
  42. ncbi Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7
    C Gorbea
    Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    J Biol Chem 275:875-82. 2000
    ..H., Rubin, D. M., Coux, O., Wefes, I., Pfeifer, G., Cejka, Z., Baumeister, W., Fried, V. A., and Finley, D. (1998) Cell 94, 615-623)...
  43. ncbi Isolation and characterization of the mouse ribosomal protein S7 gene
    T Annilo
    Tartu University, Institute of Molecular and Cell Biology, Estonian Biocentre, Estonia
    Biochem Mol Biol Int 46:287-95. 1998
    ..The promoter region of rpS7 contains several evolutionarily conserved putative regulatory elements...
  44. pmc Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells
    S Jäkel
    Zentrum fur Molekulare Biologie der Universitat Heidelberg, Germany
    EMBO J 17:4491-502. 1998
    ..The presence of distinct binding sites for rpL23a and the M9 import signal in transportin, and for rpL23a and importin alpha in importin beta might explain how a single receptor can recognize very different import signals...
  45. ncbi A ribosomal protein gene cluster is encoded in the mitochondrial DNA of Dictyostelium discoideum: UGA termination codons and similarity of gene order to Acanthamoeba castellanii
    M Iwamoto
    Institute of Biological Sciences, University of Tsukuba, Japan
    Curr Genet 33:304-10. 1998
    ..protein genes and six open reading frames (ORFs) formed a cluster arranged in the order: rpl11-orf189-rps12-rps7-rpl2-rps19-+ ++orf425-orf1740-rpl16-rpl14-orf188- rps14-rps8-rpl6-rps13-orf127-orf796...
  46. ncbi Characterization and regulation of the genes encoding ribosomal proteins L39 and S7 of the human pathogen Candida albicans
    S Delbruck
    Institut fur Mikrobiologie, Heinrich Heine Universitat, Dusseldorf, Germany
    Yeast 13:1199-210. 1997
    Genes encoding the Candida albicans ribosomal proteins L39 and S7 (RPL39, RPS7) were isolated and sequenced. From RPL39 cDNA a single intron interrupting the fifth codon in the genomic sequence could be deduced...
  47. ncbi Cloning and characterization of a Neurospora crassa ribosomal protein gene, crps-7
    P J Vierula
    Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada
    Curr Genet 31:139-43. 1997
    ..analysis and a computerized database search revealed a high degree of homology to the Xenopus laevis rps8 and rat rps7 gene, as well as to uncharacterized ORFs from two yeast species...
  48. ncbi Arrangement and nucleotide sequence of the gene (fus) encoding elongation factor G (EF-G) from the hyperthermophilic bacterium Aquifex pyrophilus: phylogenetic depth of hyperthermophilic bacteria inferred from analysis of the EF-G/fus sequences
    M Bocchetta
    Istituto Pasteur Fondazione Cenci Bolognetti, Dipartimento di Biopatologia Umana, Universita di Roma I La Sapienza, Policlinico Umberto I, Italy
    J Mol Evol 41:803-12. 1995
    ..Unlike the other bacteria, which display the streptomycin-operon arrangement of EF genes (5'-rps12-rps7-fus-tuf-3'), the Aquifex fus gene (700 codons) is not preceded by the two small ribosomal subunit genes although it ..
  49. ncbi Structural arrangement of the codon-anticodon interaction area in human placenta ribosomes. Affinity labelling of the 40S subunits by derivatives of oligoribonucleotides containing the AUG codon
    D A Mundus
    Novosibirsk Institute of Bioorganic Chemistry, Siberian Division of Russian Academy of Sciences
    Biochim Biophys Acta 1173:273-82. 1993
    ..The proteins S5 and S9 were labelled by the 5' end derivative of pAUGU3, and the protein S17 was modified by the 5' end derivative of pAUG...
  50. ncbi Functional loss of all ndh genes in an otherwise relatively unaltered plastid genome of the holoparasitic flowering plant Cuscuta reflexa
    G Haberhausen
    Institut für Pflanzenphysiologie, Justus Liebig Universitat, Giessen, Germany
    Plant Mol Biol 24:217-22. 1994
    ..ndhB), three transfer RNAs (trnA, trnI, trnV) as well as the gene coding for the ribosomal protein S7 (rps7). While the other genes are strongly conserved in C...
  51. ncbi Chromosomal organization and nucleotide sequence of the fus-gene encoding elongation factor 2 (EF-2) of the hyperthermophilic archaeum Pyrococcus woesei
    R Creti
    Istituto Pasteur Fondazione Cenci Bolognetti, Universita di Roma I, Dipartimento di Biopatologia Umana, Italy
    FEMS Microbiol Lett 126:85-90. 1995
    ..Unlike Methanococcus vannielii (which displays the 'str operon'-like fus and tuf gene context, 5'-rps12-rps7-fus-tuf-3'), and similar to Sulfolobus acidocaldarius and Desulfurococcus mobilis, the Pyrococcus fus gene (732 ..
  52. ncbi Genes for the ribosomal proteins S12 and S7 and elongation factors EF-G and EF-Tu of the cyanobacterium, Anacystis nidulans: structural homology between 16S rRNA and S7 mRNA
    B Y Meng
    Center for Gene Research, Nagoya University, Japan
    Mol Gen Genet 216:25-30. 1989
    ..The arrangement is rps12 (124 codons) - 167 bp spacer - rps7 (156 codons) - 77 bp spacer - fus (694 codons) - 26 bp spacer - tufA (409 codons), which is similar to that of the ..
  53. ncbi Genes for the plastid elongation factor Tu and ribosomal protein S7 and six tRNA genes on the 73 kb DNA from Astasia longa that resembles the chloroplast DNA of Euglena
    G Siemeister
    Botanisches Institut, Universitat Bonn, Federal Republic of Germany
    Mol Gen Genet 220:425-32. 1990
    ..The genes for the plastid elongation factor Tu (tufA) and the ribosomal protein S7 (rps7), six tRNA genes (trnQ, trnS, trnG, trnM, trnT, trnR), and three open reading frames were identified...
  54. ncbi cDNA cloning of cytoplasmic ribosomal protein S7 of winter rye (Secale cereale) and its expression in low-temperature-treated leaves
    T Berberich
    Botanisches Institut, Goethe Universitaet, Siesmayerstr 70, D 60323 Frankfurt Main, Germany
    Biochim Biophys Acta 1492:276-9. 2000
    ..A RPS7 mRNA accumulation is higher in the meristematic zone at the leaf base than in the non-meristematic middle and upper ..
  55. pmc Chloroplast ribosomal protein S7 of Chlamydomonas binds to chloroplast mRNA leader sequences and may be involved in translation initiation
    D C Fargo
    Developmental, Cell and Molecular Biology Group, Duke University LSRC Building, Box 91000 Research Drive, Durham, North Carolina 27708, USA
    Plant Cell 13:207-18. 2001
    Certain mutations isolated in the 5' untranslated region (5'UTR) of the chloroplast rps7 gene in Chlamydomonas reduce expression of reporter genes. Second site suppressors in this 5'UTR sequence restore reporter expression...
  56. doi On the brink of holoparasitism: plastome evolution in dwarf mistletoes (Arceuthobium, Viscaceae)
    Daniel L Nickrent
    Department of Plant Biology, Southern Illinois University, Carbondale, IL 62901 6509, USA
    J Mol Evol 68:603-15. 2009
    Chloroplast sequences spanning rps7 to 23S rDNA in Arceuthobium campylopodum and A. pendens were generated and compared to Arabidopsis and seven other parasitic plants...
  57. pmc Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients
    Hanna T Gazda
    Division of Genetics and Program in Genomics, The Manton Center for Orphan Disease Research, Children s Hospital Boston, Boston, MA 02115, USA
    Am J Hum Genet 83:769-80. 2008
    ..the second known mutation in RPS17 and probable pathogenic mutations in three more RP genes, RPL5, RPL11, and RPS7. In addition, we identified rare variants of unknown significance in three other genes, RPL36, RPS15, and RPS27A...
  58. pmc The role of human ribosomal proteins in the maturation of rRNA and ribosome production
    Sara Robledo
    Department of Internal Medicine, Division of Hematology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    RNA 14:1918-29. 2008
    ..We depleted HeLa cells using siRNA for several individual r-proteins of the small (RPS6, RPS7, RPS15, RPS16, RPS17, RPS19, RPS24, RPS25, RPS28) or large subunit (RPL5, RPL7, RPL11, RPL14, RPL26, RPL35a) and ..
  59. doi Tracing plant Mitochondrial DNA evolution: rearrangements of the ancient mitochondrial gene cluster trnA-trnT-nad7 in liverwort phylogeny
    Ute Wahrmund
    IZMB Institut für Zelluläre und Molekulare Botanik, Abt Molekulare Evolution, Universitat Bonn, Kirschallee 1, 53115 Bonn, Germany
    J Mol Evol 66:621-9. 2008
    ..The recombinogenic insertion of short sequence stretches, including nad5 and rps7 pseudogene fragments copied from elsewhere in the liverwort mtDNA, likely mediated a subsequent inversion of trnT ..
  60. ncbi A validation of 10 feline reference genes for gene expression measurements in snap-frozen tissues
    Louis C Penning
    Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, PO Box 80154, 3508 TD Utrechet, The Netherlands
    Vet Immunol Immunopathol 120:212-22. 2007
    ..g. RPL17, RPL30, RPS7, YWHAZ, and HPRT) were required to obtain highly reliable data in cat tissues...
  61. pmc Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5
    Oleksandr Galkin
    Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio 44115, USA
    RNA 13:2116-28. 2007
    Ribosomal protein (rp) S5 belongs to a family of ribosomal proteins that includes bacterial rpS7. rpS5 forms part of the exit (E) site on the 40S ribosomal subunit and is essential for yeast viability...
  62. ncbi Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function
    D Chen
    Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Oncogene 26:5029-37. 2007
    ..The identification of S7 as a novel MDM2-interacting partner contributes to elucidation of the complex regulation of the MDM2-p53 interaction and has implications in cancer prevention and therapy...
  63. ncbi Identification of novel ARF binding proteins by two-hybrid screening
    Van Tompkins
    Department of Pharmacology, The University of Iowa, College of Medicine, Iowa City 52242, USA
    Cell Cycle 5:641-6. 2006
    ..The potential physiological roles of these novel ARF binding proteins in regulating ARF signaling are discussed...
  64. ncbi A 60 kDa COX1 protein in mitochondria of carrot irrespective of the presence of C-terminal extensions in the cox1 reading frames
    Mary M Robison
    Department of Plant Agriculture, Bovey Bldg, University of Guelph, N1G 2W1 Guelph, ON, Canada
    Mol Genet Genomics 275:68-73. 2006
    ..The 3,159 bp repeat encodes rps7 and cox1, but the cox1 reading frame does not encode a stop codon at a position predicted by alignment with other ..
  65. ncbi Evolution of the trnF(GAA) gene in Arabidopsis relatives and the brassicaceae family: monophyletic origin and subsequent diversification of a plastidic pseudogene
    Marcus A Koch
    Heidelberg Institute of Plant Science, Heidelberg University, Heidelberg, Germany
    Mol Biol Evol 22:1032-43. 2005
    ..nonrandomly throughout the plastome, and we found some similarities with a DNA sequence duplication in the rps7 gene and its adjacent spacer...
  66. ncbi A nucleus-encoded factor, CRR2, is essential for the expression of chloroplast ndhB in Arabidopsis
    Mihoko Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0101, Japan
    Plant J 36:541-9. 2003
    ..CRR2 functions in the intergenic processing of chloroplast RNA between rps7 and ndhB, which is possibly essential for ndhB translation...
  67. pmc Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains
    Stefan Jäkel
    ZMBH, INF 282, D 69120 Heidelberg, Germany
    EMBO J 21:377-86. 2002
    ..Imp4a mediates import of the ribosomal protein (rp) S3a, while Imp9a and Imp9b import rpS7, rpL18a and apparently numerous other substrates...
  68. ncbi Mapping genes conferring resistance to Phytophthora root rot of soybean, Rps1a and Rps7
    C Weng
    Agriculture and Agri Food Canada, Greenhouse and Processing Crop Research Centre, 2585 Highway 20 E, Harrow, Ontario, N0R 1G0 Canada
    J Hered 92:442-6. 2001
    A linkage map was constructed for two Phytophthora sojae Kauf. +Gerd. root rot resistance genes, Rps1a and Rps7, in soybean (Glycine max (L.) Merr.) using microsatellite or simple sequence repeat (SSR) markers...
  69. ncbi Unusual organization of a ribosomal protein operon in the plastid genome of Cryptomonas phi: evolutionary considerations
    S E Douglas
    Atlantic Research Laboratory, National Research Council, Halifax, Nova Scotia, Canada
    Curr Genet 19:289-94. 1991
    ..Sequence analysis shows the gene organization to be rps12-60 bp spacer-rps7-68 bp spacer-tufA. No introns are present in any of the genes...

Research Grants6

  1. TRANSFER OF ORGANELLE GENES TO THE NUCLEUS
    Jeffrey Palmer; Fiscal Year: 2000
    ..or gene substitution events have occurred across all three genetic compartments for the ribosomal protein gene rps7; 3) determine whether chloroplast genes are transferred to the nucleus via RNA intermediates; 4) test the ..
  2. Regulation of p53 tumor suppressor protein
    Carol Prives; Fiscal Year: 2010
    ..that stress signaling to p53 involves nucleolar disruption, is relevant to our finding that ribosomal protein RPS7 is both a regulator and substrate of Mdm2 and that RPS7 impacts the activity of Mdm2 after various forms of stress...