RPL22

Summary

Gene Symbol: RPL22
Description: ribosomal protein L22
Alias: EAP, HBP15, HBP15/L22, L22, 60S ribosomal protein L22, EBER-associated protein, Epstein-Barr virus small RNA-associated protein, Epstein-Barr-encoded RNA-associated protein, heparin-binding protein 15, heparin-binding protein HBp15, large ribosomal subunit protein eL22
Species: human
Products:     RPL22

Top Publications

  1. Chen H, Wang Q, Yin Y, Li S, Niu D, Wang H. Genotypic variations between wild-type and small colony variant of Staphylococcus aureus in prosthetic valve infectious endocarditis: a comparative genomic and transcriptomic analysis. Int J Antimicrob Agents. 2018;51:655-658 pubmed publisher
    ..acyltransferase (plsY), 2-deoxyribose-5-phosphate aldolase (deoC), extracellular adherence protein (eap), iron compound ABC uptake transporter substrate-binding protein (sstD), RecU Holliday junction resolvase (recU), ..
  2. Gaston T, Szaflarski J. Cannabis for the Treatment of Epilepsy: an Update. Curr Neurol Neurosci Rep. 2018;18:73 pubmed publisher
    ..b>EAP data demonstrate other possible interactions with rufinamide, zonisamide, topiramate, and eslicarbazepine...
  3. Delvalle N, Dharshika C, Morales Soto W, Fried D, Gaudette L, Gulbransen B. Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on Neuroinflammation. Cell Mol Gastroenterol Hepatol. 2018;6:321-344 pubmed publisher
    ..We used Sox10::CreERT2+/-/Rpl22tm1.1Psam/J mice to selectively study glial transcriptional changes...
  4. Wang F, Wu P, Chen S. Distribution of virulence genes in bacteremic methicillin-resistant Staphylococcus aureus isolates from various sources. J Microbiol Immunol Infect. 2019;: pubmed publisher
    ..The prevalent genes in the group of infective endocarditis were clfA, clfB, fnbA, ebpS, eap, emp, sae, and eno; bone/joint infections clfA, emp, sae, and eno; skin/soft tissue infection eno; hemodialysis ..
  5. Hall T, McQuillan C, Finlay E, O Farrelly C, Fair S, Meade K. Comparative genomic identification and validation of ?-defensin genes in the Ovis aries genome. BMC Genomics. 2017;18:278 pubmed publisher
    ..27 with almost uniform similarity, as well as to tracheal, enteric and lingual anti-microbial peptides (TAP, EAP and LAP), suggesting that annotation of the bovine reference sequence is still incomplete...
  6. Gandara L, Mamone L, Dotto C, Buzzola F, Casas A. Sae regulator factor impairs the response to photodynamic inactivation mediated by Toluidine blue in Staphylococcus aureus. Photodiagnosis Photodyn Ther. 2016;16:136-141 pubmed publisher
    ..the other hand, the two component system sae impaired the response to TB-PDI through a mechanism not related to the Eap adhesin. More severe conditions were needed to inactivate S. aureus biofilms (0...
  7. Kumar P, Kretzschmar B, Herold S, Nau R, Kreutzfeldt M, Schütze S, et al. Beneficial effect of chronic Staphylococcus aureus infection in a model of multiple sclerosis is mediated through the secretion of extracellular adherence protein. J Neuroinflammation. 2015;12:22 pubmed publisher
    ..Using a S. aureus strain that lacked the extracellular adherence protein (Eap), we determined that the extracellular adherence protein is at least partially responsible for the inhibitory ..
  8. Goudarzi K, Lindström M. Role of ribosomal protein mutations in tumor development (Review). Int J Oncol. 2016;48:1313-24 pubmed publisher
    ..Mutations in ribosomal protein genes have for example been found in endometrial cancer (RPL22), T-cell acute lymphoblastic leukemia (RPL10, RPL5 and RPL11), chronic lymphocytic leukemia (RPS15), colorectal ..
  9. Puighermanal E, Biever A, Espallergues J, Gangarossa G, De Bundel D, Valjent E. drd2-cre:ribotag mouse line unravels the possible diversity of dopamine d2 receptor-expressing cells of the dorsal mouse hippocampus. Hippocampus. 2015;25:858-75 pubmed publisher
    ..To address this issue, mice expressing the ribosomal protein Rpl22 tagged with the hemagglutinin (HA) epitope were crossed with Drd2-Cre mice allowing the selective expression of HA ..

More Information

Publications119 found, 100 shown here

  1. Kirschneck C, Batschkus S, Proff P, Kostler J, Spanier G, Schröder A. Valid gene expression normalization by RT-qPCR in studies on hPDL fibroblasts with focus on orthodontic tooth movement and periodontitis. Sci Rep. 2017;7:14751 pubmed publisher
    ..Overall PPIB (peptidylprolyl isomerase A), TBP (TATA-box-binding protein) and RPL22 (ribosomal protein 22) were found to be most stably expressed with two genes in conjunction sufficient for ..
  2. Miftahussurur M, Shrestha P, Subsomwong P, Sharma R, Yamaoka Y. Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal. BMC Microbiol. 2016;16:256 pubmed
    ..2 %) of clarithromycin resistant strains had point mutation on A2143G and A2146G, we confirmed the involvement of rpl22 and infB in high MIC strains without an 23SrRNA mutation...
  3. Kim S, Shakya A, Kim S, O Callaghan D. Functional Characterization of the Serine-Rich Tract of Varicella-Zoster Virus IE62. J Virol. 2016;90:959-71 pubmed publisher
    ..The SRT of IE62 interacted with the nucleolar-ribosomal protein EAP, which resulted in the formation of globular structures within the nucleus...
  4. Dong W, Wang R, Zhang N, Fan W, Fang M, Li Z. Molecular Evolution of Chloroplast Genomes of Orchid Species: Insights into Phylogenetic Relationship and Adaptive Evolution. Int J Mol Sci. 2018;19: pubmed publisher
    ..Interestingly, we identified 16 genes with positive selection sites (the psbH, petD, petL, rpl22, rpl32, rpoC1, rpoC2, rps12, rps15, rps16, accD, ccsA, ..
  5. Fránová J, Koloniuk I, Lenz O, Sakalieva D. Molecular diversity of "Candidatus Phytoplasma mali" strains associated with apple proliferation disease in Bulgarian germplasm collection. Folia Microbiol (Praha). 2018;: pubmed publisher
    ..for the secY gene (one previously known: secY(X)-A, and three new: secY-C, secY-D, secY-E), three profiles for the rpl22-rps3 genes (rpX-A, rpX-B, rpX-F), and one profile for the nitroreductase- and rhodanese-like gene (AT-1)...
  6. Yamamoto M, Nishimori H, Fukutomi T, Yamaguchi T, Orihashi K. Dynamics of Oxidative Stress Evoked by Myocardial Ischemia Reperfusion After Off-Pump Coronary Artery Bypass Grafting Elucidated by Bilirubin Oxidation. Circ J. 2017;81:1678-1685 pubmed publisher
    ..study included 18 patients who underwent OPCAB; patients were divided into effort angina pectoris (EAP; n=11) and unstable angina pectoris (UAP; n=7)...
  7. Kim K, Nguyen V, Dong J, Wang Y, Park J, Lee S, et al. Evolution of the Araliaceae family inferred from complete chloroplast genomes and 45S nrDNAs of 10 Panax-related species. Sci Rep. 2017;7:4917 pubmed publisher
    ..Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks ..
  8. Murphy S, Hall C, Done J, Schaeffer A, Thumbikat P. A prostate derived commensal Staphylococcus epidermidis strain prevents and ameliorates induction of chronic prostatitis by UPEC infection. Sci Rep. 2018;8:17420 pubmed publisher
    ..inducing), from a healthy subject reduces pain and inflammation in an experimental autoimmune prostatitis (EAP) murine model...
  9. Pérez Alvarado C, Gomez C, Reyes M, Garcia M, Perez E, Pérez de la Mora C, et al. Anti-Inflammatory Effect of Dialyzable Leukocyte Extract in Autoimmune Prostatitis: Evaluation in Animal Model. Biomed Res Int. 2017;2017:1832853 pubmed publisher
    ..On the other hand, the expression of anti-inflammatory cytokine IL-4 increased in both the Dexamethasone and DLE groups. Conclusion. DLE is able to modulate the inflammatory response in Experimental Autoimmune Prostatitis (EAP).
  10. Romero Pastrana F, Neef J, Koedijk D, de Graaf D, Duipmans J, Jonkman M, et al. Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins. Sci Rep. 2018;8:3234 pubmed publisher
    ..Ten non-covalently cell surface-bound proteins of S. aureus, namely Atl, Eap, Efb, EMP, IsaA, LukG, LukH, SA0710, Sle1 and SsaA2, were selected by bioinformatics and biochemical approaches...
  11. Lin H, Wang M, Yu Y, Qin Z, Zhong X, Ma J, et al. Efficacy and tolerability of pharmacological interventions for pulmonary arterial hypertension: A network meta-analysis. Pulm Pharmacol Ther. 2018;50:1-10 pubmed publisher
    ..mRAP), endothelin receptor antagonists (ERA), phosphodiesterase 5 inhibitor (PDE-5Is), ERA combined with PDE-5Is (EAP), and prostacyclin analogs (PGI) combined with ERA (PAE) performed better than others...
  12. Grossman Z, Hadjipanayis A, Stiris T, del Torso S, Mercier J, Valiulis A, et al. Vitamin D in European children-statement from the European Academy of Paediatrics (EAP). Eur J Pediatr. 2017;176:829-831 pubmed publisher
    ..Beyond this age, seasonal variation of sunlight should be taken into account when considering a national policy of supplementation or fortification. ..
  13. Foster G, Irving W, Cheung M, Walker A, Hudson B, Verma S, et al. Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis. J Hepatol. 2016;64:1224-31 pubmed publisher
    ..HCV and decompensated cirrhosis or at risk of irreversible disease were treated in an expanded access programme (EAP) in 2014. Treatment, by clinician choice, was with sofosbuvir, ledipasvir or daclatasvir, with or without ribavirin...
  14. Lizier T, Boldrin Zanoni M. Effect of ionic liquid on the determination of aromatic amines as contaminants in hair dyes by liquid chromatography coupled to electrochemical detection. Molecules. 2012;17:7961-79 pubmed publisher
    ..8 mL·min⁻¹, column CLC-ODS, Eap = +1.0 V and T = 40 °C analytical curves were constructed for each of the tested amines...
  15. Cheraghi S, Pourgholi L, Shafaati M, Fesharaki S, Jalali A, Nosrati R, et al. Analysis of virulence genes and accessory gene regulator (agr) types among methicillin-resistant Staphylococcus aureus strains in Iran. J Glob Antimicrob Resist. 2017;10:315-320 pubmed publisher
    ..Furthermore, the most frequent adhesin genes were clfA, spa, cna, map/eap and bbp, found in 281 (94.9%), 275 (92.9%), 267 (90.2%), 265 (89.5%) and 264 (89.2%) isolates, respectively...
  16. Cuevas D, Valls J, Gatius S, Roman Canal B, Estaran E, Dorca E, et al. Targeted sequencing with a customized panel to assess histological typing in endometrial carcinoma. Virchows Arch. 2019;: pubmed publisher
    ..ERBB2, FBXW7, FGFR2, FOXA2, KLLN, KMT2B, KRAS, MAP3K4, MKI67, NRAS, PGAP3, PIK3CA, PIK3R1, PPP2R1A, PRPF18, PTEN, RPL22, SCARNA11, SIN3A, SMARCA4, SPOP, TAF1, TP53, TSPYL2, USP36, and WRAP53...
  17. Zou Y, Deng W, Wang F, Yu X, Liu F, Yang B, et al. A novel somatic MAPK1 mutation in primary ovarian mixed germ cell tumors. Oncol Rep. 2016;35:725-30 pubmed publisher
    ..POLE1), ribonuclease type III (DICER1), CCCTC‑binding factor (CTCF), ribosomal protein L22 (RPL22), DNA methyltransferase 3α (DNMT3A), transformation/transcription domain‑associated protein (TRRAP), ..
  18. Stratmann J, Michels S, Hornetz S, Christoph D, Sackmann S, Spengler W, et al. Efficacy and safety analysis of the German expanded access program of osimertinib in patients with advanced, T790M-positive non-small cell lung cancer. J Cancer Res Clin Oncol. 2018;144:2457-2463 pubmed publisher
    ..We performed a retrospective data analysis on patients who were included into the German osimertinib EAP. Of 81 patients enrolled, 51 patients (62...
  19. Liu M, Fan W, Wang N, Dong P, Zhang T, Yue M, et al. Evolutionary Analysis of Plastid Genomes of Seven Lonicera L. Species: Implications for Sequence Divergence and Phylogenetic Relationships. Int J Mol Sci. 2018;19: pubmed publisher
    ..which included four genes for the subunits of ribosome proteins (rps7, rpl2, rpl16, and rpl22), three genes for the subunits of photosystem proteins (psaJ, psbC, and ycf4), three NADH ..
  20. Martin G, Rousseau Gueutin M, Cordonnier S, Lima O, Michon Coudouel S, Naquin D, et al. The first complete chloroplast genome of the Genistoid legume Lupinus luteus: evidence for a novel major lineage-specific rearrangement and new insights regarding plastome evolution in the legume family. Ann Bot. 2014;113:1197-210 pubmed publisher
    ..luteus vs. Fabaceae and extra-Fabales plastomes revealed the loss of the plastid rpl22 gene, and its functional relocation to the nucleus was verified using lupine transcriptomic data...
  21. Choudhary R, Kumar S, Singh S, Sharma A, Goud T, Srivastava A, et al. Validation of putative reference genes for gene expression studies in heat stressed and α-MSH treated melanocyte cells of Bos indicus using real-time quantitative PCR. Mol Cell Probes. 2016;30:161-7 pubmed publisher
    ..A total of 15 IRGs (ACTB, BZM, EEF1, GAPDH, GTP, HMBS, HPRT, RPL22, RPL4, RPS15, RPS18, RPS23, RPS9, UBC and UXT) from different functional classes were evaluated...
  22. Nam J, Yates M, Zaybak Z, Logan B. Examination of protein degradation in continuous flow, microbial electrolysis cells treating fermentation wastewater. Bioresour Technol. 2014;171:182-6 pubmed publisher
    ..0 or 1.2 V), but current generation was erratic due to more positive anode potentials (-113±38 mV, Eap=1.2V; -338±38 mV, 1.0 V; -0.426±4 mV, 0.9V)...
  23. Lin S, Chang K, Hsu C, Chi L, Chien K, Liang Y, et al. Low-molecular-mass secretome profiling identifies C-C motif chemokine 5 as a potential plasma biomarker and therapeutic target for nasopharyngeal carcinoma. J Proteomics. 2013;94:186-201 pubmed publisher
    ..We verified the overexpression of four targets (LSM2, SUMO1, RPL22, and CCL5) in NPC tissues by immunohistochemistry and demonstrated elevated plasma levels of two targets (S100A2 ..
  24. de Jong N, Ploscariu N, Ramyar K, Garcia B, Herrera A, Prakash O, et al. A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN). J Biol Chem. 2018;293:2260-2271 pubmed publisher
    ..Degradation of SPIN was prevented by the S. aureus immune evasion protein Eap, which acts as a selective inhibitor of neutrophil serine proteases...
  25. Liu Q, Hu M, Yeo W, He L, Li T, Zhu Y, et al. Rewiring of the FtsH regulatory network by a single nucleotide change in saeS of Staphylococcus aureus. Sci Rep. 2017;7:8456 pubmed publisher
    ..Due to the increase of SaeS L18P in the ftsH mutant, Eap, a sae-regulon protein, was also increased in abundance, causing the Newman-specific cell-aggregation phenotype...
  26. Liu D, Li Z, Wang G, Li T, Zhang L, Tang P. Virulence analysis of Staphylococcus aureus in a rabbit model of infected full-thickness wound under negative pressure wound therapy. Antonie Van Leeuwenhoek. 2018;111:161-170 pubmed publisher
    ..The agrA expression of S.aureus and the transcription and production of virulence factors including Eap, Spa and ?-toxin were significantly different...
  27. Ploscariu N, Herrera A, Jayanthi S, Suresh Kumar T, Geisbrecht B, Prakash O. Backbone and side-chain 1H, 15N, and 13C resonance assignments of a novel Staphylococcal inhibitor of myeloperoxidase. Biomol NMR Assign. 2017;11:285-288 pubmed publisher
    ..Recently, novel classes of secreted proteins from S. aureus, including the Extracellular Adherence Protein (EAP) family (Stapels et al...
  28. Aoyama S, Kojima S, Sasaki K, Ishikawa R, Tanaka M, Shimoda T, et al. Day-Night Oscillation of Atrogin1 and Timing-Dependent Preventive Effect of Weight-Bearing on Muscle Atrophy. EBioMedicine. 2018;37:499-508 pubmed publisher
    ..effects of weight-bearing, mice were released from HU for 4 h in a day at early or late active phase (W-EAP and W-LAP groups, respectively)...
  29. Manukumar H, Umesha S. MALDI-TOF-MS based identification and molecular characterization of food associated methicillin-resistant Staphylococcus aureus. Sci Rep. 2017;7:11414 pubmed publisher
    ..01), strains characterized by means of nuc genes, followed by species specific identification by Coa, Eap and SpA genes and multiplex PCR to confirm the presence of three methicillin resistant staphylococcal species ..
  30. Rashkovan M, Vadnais C, Ross J, Gigoux M, Suh W, Gu W, et al. Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombination. Proc Natl Acad Sci U S A. 2014;111:E5411-9 pubmed publisher
    ..Miz-1 exerts this function by directly activating the gene for ribosomal protein L22 (Rpl22), which binds to p53 mRNA and negatively regulates its translation...
  31. Luna Coronell J, Sergelen K, Höfer P, Gyurján I, Brezina S, Hettegger P, et al. The Immunome of Colon Cancer: Functional In Silico Analysis of Antigenic Proteins Deduced from IgG Microarray Profiling. Genomics Proteomics Bioinformatics. 2018;16:73-84 pubmed publisher
    ..Ribosomal proteins (e.g., RPL7, RPL22, and RPL27A) and CRC-related genes such as APC, AXIN1, E2F4, MSH2, PMS2, and TP53 were highly enriched...
  32. Majima R, Shindoh K, Yamaguchi T, Inoue N. Characterization of a thienylcarboxamide derivative that inhibits the transactivation functions of cytomegalovirus IE2 and varicella zoster virus IE62. Antiviral Res. 2017;140:142-150 pubmed publisher
    ..herpesvirus promoters and examined whether 133G4 affects the functions of cellular proteins USF1, TBP, Med25 and EAP, the involvement of which in VZV IE62-dependent viral gene activation has been well characterized...
  33. Gabunilas J, Chanfreau G. Splicing-Mediated Autoregulation Modulates Rpl22p Expression in Saccharomyces cerevisiae. PLoS Genet. 2016;12:e1005999 pubmed publisher
    ..These results demonstrate an autoregulatory mechanism that fine-tunes the expression of the Rpl22 protein and by extension Rpl22p paralog composition according to the cellular demands for ribosome biogenesis.
  34. C Zapico S, Menendez S. Human mitochondrial DNA and nuclear DNA isolation from food bite marks. Arch Oral Biol. 2016;70:67-72 pubmed publisher
    ..Moreover, apple samples failed to amplify the two human housekeeping genes, GAPDH and RPL22. In contrast, cheese samples have high purity and amplification efficiency...
  35. Ludvigsson J, Stiris T, del Torso S, Mercier J, Valiulis A, Hadjipanayis A. European Academy of Paediatrics Statement: Vision zero for child deaths in traffic accidents. Eur J Pediatr. 2017;176:291-292 pubmed publisher
    ..The European Academy of Pediatrics (EAP) strives to prevent morbidity and death in children...
  36. Fu C, Li H, Milne R, Zhang T, Ma P, Yang J, et al. Comparative analyses of plastid genomes from fourteen Cornales species: inferences for phylogenetic relationships and genome evolution. BMC Genomics. 2017;18:956 pubmed publisher
    ..Two genes (rpl22 and ycf15) contained premature stop codons in seven and five species respectively...
  37. Fang X, Fry D, Brown D, Mercy J, Dunne M, Butchart A, et al. The burden of child maltreatment in the East Asia and Pacific region. Child Abuse Negl. 2015;42:146-62 pubmed publisher
    ..The estimated economic value of DALYs (in constant 2000 US$) lost to child maltreatment in the EAP region totaled US $151 billion, accounting for 1.88% of the region's GDP...
  38. Kim J, Kim J. Comparative genome analysis and phylogenetic relationship of order Liliales insight from the complete plastid genome sequences of two Lilies (Lilium longiflorum and Alstroemeria aurea). PLoS ONE. 2013;8:e68180 pubmed publisher
    ..Ka/Ks ratio was high in matK among the pair-wise comparison of three families and the most variable genes were psaJ, ycf1, rpl32, rpl22, matK, and ccsA among the three families and rps15, rpoA, matK, and ndhF between Lilium.
  39. Zheng S, Cherniack A, Dewal N, Moffitt R, Danilova L, Murray B, et al. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell. 2016;29:723-736 pubmed publisher
    ..Using this dataset, we expand the catalogue of known ACC driver genes to include PRKAR1A, RPL22, TERF2, CCNE1, and NF1...
  40. La Foresta S, Faraone C, Sframeli M, Vita G, Russo M, Profazio C, et al. Intrathecal administration of Nusinersen in type 1 SMA: successful psychological program in a single Italian center. Neurol Sci. 2018;39:1961-1964 pubmed publisher
    ..We report our experience during expanded access program (EAP) for type 1 SMA in a single Italian center...
  41. Gottschling S, Herpel E, Eberhardt W, Heigener D, Fischer J, Köhne C, et al. The gefitinib long-term responder (LTR)--a cancer stem-like cell story? Insights from molecular analyses of German long-term responders treated in the IRESSA expanded access program (EAP). Lung Cancer. 2012;77:183-91 pubmed publisher
    ..Cancer stem-like cells (CSC) are thought to play a pivotal role in tumor regeneration and appear to be influenced by the EGFR-pathway. This makes them a promising candidate for predicting long-term response to EGFR-TKIs...
  42. Roquet C, Coissac E, Cruaud C, Boleda M, Boyer F, Alberti A, et al. Understanding the evolution of holoparasitic plants: the complete plastid genome of the holoparasite Cytinus hypocistis (Cytinaceae). Ann Bot. 2016;: pubmed
    ..On the other hand, increased selection intensity and strong positive selection were detected for rpl22 in the Cytinus lineage, which might indicate an evolutionary role in the host-parasite arms race, a point that ..
  43. Aitini E, Rabbi C, Mambrini A, Cavazzini G, Pari F, Zamagni D, et al. Epirubicin, cisplatin and continuous infusion 5-fluorouracil (ECF) in locally advanced or metastatic gastric cancer: a single institution experience. Tumori. 2001;87:20-4 pubmed
    ..chemotherapy regimens were developed in the 1980s with high activity in advanced or metastatic gastric cancer (EAP, FAMTX, PELF, ECF)...
  44. Xie H, Clifford J, Squires J, Chen C, Bian X, Yu Q. Adapting and validating a developmental assessment for chinese infants and toddlers: The ages & stages questionnaires: Inventory. Infant Behav Dev. 2017;49:281-295 pubmed publisher
    ..96 across five domains. When using the whole sample for analyses, item expected a posteriori/plausible value (EAP/PV) reliability was above 0...
  45. Dalan A, Gulluoglu S, Tuysuz E, Kuskucu A, Yaltırık C, Ozturk O, et al. Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c. BMC Cancer. 2017;17:207 pubmed publisher
    ..CABIN1, miR-29c, TMOD1, PTX3, RPL22, SPARCL1 and RELA were correlated with clinicopathological features in patient samples...
  46. Sun Y, Moore M, Meng A, Soltis P, Soltis D, Li J, et al. Complete plastid genome sequencing of Trochodendraceae reveals a significant expansion of the inverted repeat and suggests a Paleogene divergence between the two extant species. PLoS ONE. 2013;8:e60429 pubmed publisher
    ..but both genomes have the same unusual ∼4 kb expansion of the inverted repeat region to include five genes (rpl22, rps3, rpl16, rpl14, and rps8) that are normally found in the large single-copy region...
  47. Gregorovic G, Boulden E, Bosshard R, Elgueta Karstegl C, Skalsky R, Cullen B, et al. Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice. J Virol. 2015;89:11711-4 pubmed publisher
    ..Binding of EBER1 to ribosomal protein L22 (RPL22) was confirmed...
  48. Schrier L, Hadjipanayis A, del Torso S, Stiris T, Emonts M, Dornbusch H. European Antibiotic Awareness Day 2017: training the next generation of health care professionals in antibiotic stewardship. Eur J Pediatr. 2018;177:279-283 pubmed publisher
    ..needed to prescribe antibiotics to children rationally as described in the European Academy of Paediatrics (EAP) Curriculum for Common Trunk Training in Paediatrics • Interdisciplinary approaches of education need to be ..
  49. Mazur A, Caroli M, Radziewicz Winnicki I, Nowicka P, Weghuber D, Neubauer D, et al. Reviewing and addressing the link between mass media and the increase in obesity among European children: The European Academy of Paediatrics (EAP) and The European Childhood Obesity Group (ECOG) consensus statement. Acta Paediatr. 2017;: pubmed publisher
  50. Franklin P. Public health within the EU policy space: a qualitative study of Organized Civil Society (OCS) and the Health in All Policies (HiAP) approach. Public Health. 2016;136:29-34 pubmed publisher
    ..main implementation pillar, European Action Plan for Strengthening Public Health Capacities and Services (EAP-PHS)...
  51. Waehrer G, Miller T, Hendrie D, Galvin D. Employee assistance programs, drug testing, and workplace injury. J Safety Res. 2016;57:53-60 pubmed publisher
    ..Lost-work injuries were more responsive to specific EAP characteristics, with lower rates associated with EAPs staffed by company employees (most likely onsite)...
  52. Garcia Carrillo D, Marin Lopez R. Lightweight CoAP-Based Bootstrapping Service for the Internet of Things. Sensors (Basel). 2016;16: pubmed publisher
    ..and identity federation, our design uses technologies such as the Extensible Authentication Protocol (EAP) and Authentication Authorization and Accounting (AAA). We have named this service CoAP-EAP...
  53. Eisenbeis J, Peisker H, Backes C, Bur S, Hölters S, Thewes N, et al. The extracellular adherence protein (Eap) of Staphylococcus aureus acts as a proliferation and migration repressing factor that alters the cell morphology of keratinocytes. Int J Med Microbiol. 2017;307:116-125 pubmed publisher
    ..One of these factors is the extracellular adherence protein Eap, a member of the "secretable expanded repertoire adhesive molecules" (SERAM) protein family that possesses adhesive ..
  54. Kim S, Strich R. Rpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae. Cell Div. 2016;11:10 pubmed publisher
    ..In the absence of Rpl22 function, IME1 mRNA synthesis is normal in cultures induced to enter meiosis...
  55. Silva J, Mendes R, Tomasco V, Pinto N, de Oliveira L, Rodrigues M, et al. New aspects on the hepatoprotective potential associated with the antioxidant, hypocholesterolemic and anti-inflammatory activities of Vernonia condensata Baker. J Ethnopharmacol. 2017;198:399-406 pubmed publisher
    ..hepatoprotective and antioxidant, and the in vitro anti-inflammatory activities of the ethyl acetate partition (EAP) from the ethanolic extract of this medicinal plant leaves...
  56. Richmond M, Pampel F, Wood R, Nunes A. The impact of employee assistance services on workplace outcomes: Results of a prospective, quasi-experimental study. J Occup Health Psychol. 2017;22:170-179 pubmed publisher
    ..The current study represents a major advance in EAP research by using a prospective, quasi-experimental design with a large and diverse employee base...
  57. Xu Z, Feng S, Shen S, Wang H, Yuan M, Liu J, et al. The antioxidant activities effect of neutral and acidic polysaccharides from Epimedium acuminatum Franch. on Caenorhabditis elegans. Carbohydr Polym. 2016;144:122-30 pubmed publisher
    A neutral polysaccharide (EAP-1N) and an acidic polysaccharide (EAP-2A) were purified from Epimedium acuminatum by DEAE-52 cellulose anion-exchange chromatography and gel-filtration chromatography...
  58. Piccione E, Engelstad J, Dyck P, Mauermann M, Dispenzieri A, Dyck P. Nerve pathologic features differentiate POEMS syndrome from CIDP. Acta Neuropathol Commun. 2016;4:116 pubmed
    ..Nerve biopsies were blinded and reviewed by two of the authors (EAP, PJBD). Teased fibers, paraffin-embedded sections, semithin sections and immunostains were analyzed...
  59. Herrera A, Ploscariu N, Geisbrecht B, Prakash O. 1H, 15N, and 13C resonance assignments of the third domain from the S. aureus innate immune evasion protein Eap. Biomol NMR Assign. 2018;12:175-178 pubmed publisher
    ..The extracellular adherence protein (Eap) is a multidomain protein that participates in various protein-protein interactions that inhibit the innate immune ..
  60. Yamoto M, Nakazawa Y, Fukumoto K, Miyake H, Nakajima H, Sekioka A, et al. Risk factors and prevention for surgical intestinal disorders in extremely low birth weight infants. Pediatr Surg Int. 2016;32:887-93 pubmed publisher
    ..From 2010, we performed enteral antifungal prophylaxis (EAP) in ELBWI to prevent for SID...
  61. Tumeh P, Hellmann M, Hamid O, Tsai K, Loo K, Gubens M, et al. Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC. Cancer Immunol Res. 2017;5:417-424 pubmed publisher
    ..from the phase I Keynote 001 trial, whereas the melanoma validation cohort was drawn from Keynote 002, 006, and EAP trials and the non-small cell lung cancer (NSCLC) cohort from Keynote 001...
  62. Fick R, Wassermann D, Caruyer E, Deriche R. MAPL: Tissue microstructure estimation using Laplacian-regularized MAP-MRI and its application to HCP data. Neuroimage. 2016;134:365-385 pubmed publisher
    ..Polar Fourier (mSPF) basis with respect to signal fitting and reconstruction of the Ensemble Average Propagator (EAP) and Orientation Distribution Function (ODF) in noisy, sparsely sampled data of a physical phantom with reference ..
  63. Zucchelli M, Brusini L, Andrés Méndez C, Daducci A, Granziera C, Menegaz G. What lies beneath? Diffusion EAP-based study of brain tissue microstructure. Med Image Anal. 2016;32:145-56 pubmed publisher
    ..models can be identified in diffusion magnetic resonance imaging (DMRI): ensemble average propagator (EAP) models and compartmental models...
  64. Woehl J, Ramyar K, Katz B, Walker J, Geisbrecht B. The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein. Protein Sci. 2017;26:1595-1608 pubmed publisher
    The extracellular adherence protein (Eap) plays a crucial role in pathogenesis and survival of Staphylococcus aureus by inhibiting the classical and lectin pathways of complement...
  65. Crawley F, Hoyer P, Mazur A, Siderius L, Grosek S, Stiris T, et al. Health, integrity, and doping in sports for children and young adults. A resolution of the European Academy of Paediatrics. Eur J Pediatr. 2017;176:825-828 pubmed publisher
    The European Academy of Paediatrics (EAP) is dedicated to promoting healthy lifestyles for children from birth into young adulthood...
  66. Iudicello A, Alberghini L, Benini G, Mosconi P. Expanded Access Programme: looking for a common definition. Trials. 2016;17:21 pubmed publisher
    ..for patients with a life-threating disease is permitted outside a clinical trial as an Expanded Access Programme (EAP).The regulations regarding EAPs is not the same all over the world...
  67. Stapels D, Kuipers A, von Köckritz Blickwede M, Ruyken M, Tromp A, Horsburgh M, et al. Staphylococcus aureus protects its immune-evasion proteins against degradation by neutrophil serine proteases. Cell Microbiol. 2016;18:536-45 pubmed publisher
    ..aureus produces three highly specific inhibitors for NSPs [the extracellular adherence proteins (EAPs) Eap, EapH1 and EapH2], suggests that these proteases are important for host defences against this bacterium...
  68. BIRNEY A, Gunn R, Russell J, Ary D. MoodHacker Mobile Web App With Email for Adults to Self-Manage Mild-to-Moderate Depression: Randomized Controlled Trial. JMIR Mhealth Uhealth. 2016;4:e8 pubmed publisher
    ..Participants were recruited from August 2012 through April 2013 in partnership with an EAP and with outreach through a variety of additional non-EAP organizations...
  69. Rao S, Cai K, Stadanlick J, Greenberg Kushnir N, Solanki Patel N, Lee S, et al. Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma. Cancer Res. 2016;76:3387-96 pubmed publisher
    ..We reported previously that the ribosomal protein Rpl22 is a tumor suppressor in T-cell acute lymphoblastic leukemia/lymphoma (T-ALL), and that loss of just one Rpl22 ..
  70. Yan D, Liu X, Guo S. Nerve fibers and endometriotic lesions: partners in crime in inflicting pains in women with endometriosis. Eur J Obstet Gynecol Reprod Biol. 2017;209:14-24 pubmed publisher
    ..Indeed, endometriosis-associated pain (EAP) is the most debilitating of the disease that negatively impacts on the quality of life in affected women, ..
  71. Du X, Jin J, Cai Z, Chen F, Zhou D, Yu L, et al. Long-term use of lenalidomide and low-dose dexamethasone in Chinese patients with relapsed/refractory multiple myeloma: MM-024 Extended Access Program. BMC Cancer. 2016;16:46 pubmed publisher
    ..MM-024 was an Extended Access Program (EAP) that allowed responding patients in the MM-021 trial to continue to receive Rd, and to provide additional safety ..
  72. Schneider K, Meeteer W, Nolan J, Campbell H. Health care in high school athletics in West Virginia. Rural Remote Health. 2017;17:3879 pubmed
    ..When asked if there was a written emergency action plan (EAP) that outlines procedures to follow in emergency situations during athletic participation, 36% responded 'never' ..
  73. Scott S, Harris P, Williamson D, Liss M, Doi S, Roberts M. The effectiveness of targeted relative to empiric prophylaxis on infectious complications after transrectal ultrasound-guided prostate biopsy: a meta-analysis. World J Urol. 2018;36:1007-1017 pubmed publisher
    ..biopsy and targeted antibiotic prophylaxis (TAP) may decrease post-TRUSPB infection rates compared to empiric (EAP) regimens...
  74. Huebner A, Wang C, Quinlan K, Seubert L. Item exposure control for multidimensional computer adaptive testing under maximum likelihood and expected a posteriori estimation. Behav Res Methods. 2016;48:1443-1453 pubmed
    ..Also, for the first time, maximum likelihood (MLE) and expected a posteriori (EAP) estimation of examinee ability were compared side by side in a multidimensional computer adaptive test...
  75. Zarei G, Pourghasemian H, Jalali H. Language Learners' Writing Task Representation and Its Effect on Written Performance in an EFL Context. J Psycholinguist Res. 2017;46:567-581 pubmed publisher
    The present study attempts to give an account of how students represent writing task in an EAP course. Further, the study is intended to discover if learners' mental representation of writing would contribute to their written performance...
  76. Mo F, Wang J, Li F, Nguluu S, Ren H, Zhou H, et al. Yield-phenology relations and water use efficiency of maize (Zea mays L.) in ridge-furrow mulching system in semiarid east African Plateau. Sci Rep. 2017;7:3260 pubmed publisher
    ..relation is a critical issue affecting rainfed maize field productivity in semiarid east African Plateau (EAP)...
  77. Costessi A, Mahrour N, Sharma V, Stunnenberg R, Stoel M, Tijchon E, et al. The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. PLoS ONE. 2012;7:e42822 pubmed publisher
    ..Moreover, EKC subunits associate with PRAME target sites on chromatin. Our data reveal a novel link between the oncoprotein PRAME and the conserved EKC complex and support a role for both complexes in the same pathways. ..
  78. Toczyski D, Steitz J. EAP, a highly conserved cellular protein associated with Epstein-Barr virus small RNAs (EBERs). EMBO J. 1991;10:459-66 pubmed
    ..that the EBERs also associate with a second highly abundant host-encoded protein designated EAP (EBER associated protein). Human EAP is a small (14,777 dalton, 128 amino acid) polypeptide that binds both EBER 1 and EBER 2...
  79. Le S, Sternglanz R, Greider C. Identification of two RNA-binding proteins associated with human telomerase RNA. Mol Biol Cell. 2000;11:999-1010 pubmed
    ..Here we describe the identification of two new proteins that interact with hTR: hStau and L22. Antisera against both proteins immunoprecipitated hTR, hTERT, and telomerase activity from cell extracts, ..
  80. Cao B, Fang Z, Liao P, Zhou X, Xiong J, Zeng S, et al. Cancer-mutated ribosome protein L22 (RPL22/eL22) suppresses cancer cell survival by blocking p53-MDM2 circuit. Oncotarget. 2017;8:90651-90661 pubmed publisher
    ..Here, we report ribosomal protein L22 (RPL22/eL22) as a novel p53 activator highly mutated (mostly deletion mutation) in various types of human cancers, but ..
  81. Novetsky A, Zighelboim I, Thompson D, Powell M, Mutch D, Goodfellow P. Frequent mutations in the RPL22 gene and its clinical and functional implications. Gynecol Oncol. 2013;128:470-4 pubmed publisher
    To determine the frequency and spectrum of mutations in RPL22 a gene identified by The Cancer Genome Atlas (TCGA) as mutated in endometrioid endometrial cancer, and determine the relationship between RPL22 defects and clinicopathologic ..
  82. Dornbusch H, Hadjipanayis A, del Torso S, Mercier J, Wyder C, Schrier L, et al. We strongly support childhood immunisation-statement from the European Academy of Paediatrics (EAP). Eur J Pediatr. 2017;176:679-680 pubmed publisher
    ..Therefore, the EAP calls for greater publically available, scientifically supported information on vaccination, particularly targeted ..
  83. Yang M, Sun H, Wang H, Zhang S, Yu X, Zhang L. Down-regulation of ribosomal protein L22 in non-small cell lung cancer. Med Oncol. 2013;30:646 pubmed publisher
    Ribosomal protein L22 (RPL22), an RNA-binding protein, is a constituent of the 60S large ribosomal subunit...
  84. Stapels D, Woehl J, Milder F, Tromp A, van Batenburg A, de Graaf W, et al. Evidence for multiple modes of neutrophil serine protease recognition by the EAP family of Staphylococcal innate immune evasion proteins. Protein Sci. 2017;: pubmed publisher
    ..In response, the pathogen Staphylococcus aureus has evolved three potent inhibitors (Eap, EapH1, and EapH2) that protect the bacterium as well as several of its secreted virulence factors from the ..
  85. Kim S, Buczynski K, Caughman G, O Callaghan D. The equine herpesvirus 1 immediate-early protein interacts with EAP, a nucleolar-ribosomal protein. Virology. 2001;279:173-84 pubmed
    ..IE homolog of herpes simplex virus 1 (HSV-1), revealed that a domain containing a serine-rich tract interacts with EAP (Epstein-Barr virus-encoded small nuclear RNA-associated protein), a 15-kDa nucleolar-ribosomal protein (R...
  86. Zarras P, Buhrmaster D, Webber C, Anderson N, Stenger Smith J, Goodman P. Poly(2,5-bis(N-Methyl-N-Hexylamino)Phenylene Vinylene) (BAM-PPV) as Pretreatment Coating for Aerospace Applications: Laboratory and Field Studies. Materials (Basel). 2014;7:8088-8104 pubmed publisher
    In this study, an electroactive polymer (EAP), poly(2,5-bis(N-methyl-N-hexylamino)phenylene vinylene) (BAM-PPV) was investigated as a potential alternative surface pretreatment for hexavalent chromium (Cr(VI))-based ..
  87. Fok V, Mitton Fry R, Grech A, Steitz J. Multiple domains of EBER 1, an Epstein-Barr virus noncoding RNA, recruit human ribosomal protein L22. RNA. 2006;12:872-82 pubmed
    ..in all cells transformed by Epstein-Barr virus (EBV), has been shown to associate with the human ribosomal protein L22. Here we present in vitro binding studies using purified RNAs and recombinant proteins...
  88. Rao S, Lee S, Gutierrez A, Perrigoue J, Thapa R, Tu Z, et al. Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B. Blood. 2012;120:3764-73 pubmed publisher
    ..We show here that monoallelic, germline inactivation of the ribosomal protein L22 (Rpl22) predisposes T-lineage progenitors to transformation...
  89. Corneliu Jinga D, Ciuleanu T, Negru S, Aldea C, Gales L, Bacanu F, et al. Effectiveness and safety profile of ipilimumab therapy in previously treated patients with unresectable or metastatic melanoma - the Romanian Patient Access Program. J BUON. 2017;22:1287-1295 pubmed
    The Romanian Patient Access Program (Ro-PAP, CA 184-427), part of the European Expanded Access Program (EAP), was developed to evaluate the effectiveness and safety profile ipilimumab in previously treated patients with advanced melanoma ..
  90. Ueshima K, Nishida N, Kudo M. Sorafenib-Regorafenib Sequential Therapy in Advanced Hepatocellular Carcinoma: A Single-Institute Experience. Dig Dis. 2017;35:611-617 pubmed publisher
    ..An open-label expanded access program (EAP) of regorafenib was implemented for compassionate use...
  91. Yang M, Sun H, He J, Wang H, Yu X, Ma L, et al. Interaction of ribosomal protein L22 with casein kinase 2?: a novel mechanism for understanding the biology of non-small cell lung cancer. Oncol Rep. 2014;32:139-44 pubmed publisher
    ..As reported, ribosomal protein L22 (RPL22) dysfunction could increase cancer risk...
  92. Shu Nu C, Lin C, Lin A. An acidic amino acid cluster regulates the nucleolar localization and ribosome assembly of human ribosomal protein L22. FEBS Lett. 2000;484:22-8 pubmed
    The control of human ribosomal protein L22 (rpL22) to enter into the nucleolus and its ability to be assembled into the ribosome is regulated by its sequence...