Gene Symbol: RGS6
Description: regulator of G protein signaling 6
Alias: GAP, HA117, S914, regulator of G-protein signaling 6, regulator of G-protein signalling 6
Species: human
Products:     RGS6

Top Publications

  1. Guo Y, Zheng G, Jin X, Xu Y, Luo Q, Liu X, et al. HA117 gene increased the multidrug resistance of K562 cells in vitro: an investigation to the function of a novel gene related to drug resistance. J Exp Clin Cancer Res. 2009;28:63 pubmed publisher
    A novel multi-drug resistance gene named as HA117 has been screened and cloned in multidrug resisitant leukemia cell lines in our previous research, but its function is still unknown...
  2. Sinmisola A, Bello O. A Review on Blighia Sapida K.D. Koenig (syn. Cupania sapida Voigt.)'s: Its Economic Importance, Phytochemistry and Pharmacological Activity: Channeling these Claims for the Present and Future. J Ethnopharmacol. 2019;: pubmed publisher
    ..More work is still required to authenticate these medicinal claims, this review tends to bridge the gap by providing enough information for future research since it is clear that the phytochemistry of this plant is yet ..
  3. Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Niksic M, et al. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37?513?025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018;391:1023-1075 pubmed publisher
    ..For many cancers, Denmark is closing the survival gap with the other Nordic countries...
  4. Arif T, Amin S, Adil M, Mohtashim M. Diffuse Palmoplantar Keratoderma, Onychodystrophy, universal Hypotrichosis and Cysts. Acta Dermatovenerol Croat. 2017;25:161-163 pubmed
    ..However, it has subsequently been described in other ethnic and geographical areas. There is a mutation in the ? gap junction protein gene which codes for the protein connexin 30 (Cx30) (3)...
  5. Samuels T, Yan J, Khampang P, Dettmar P, Mackinnon A, Hong W, et al. Association of Gel-Forming Mucins and Aquaporin Gene Expression With Hearing Loss, Effusion Viscosity, and Inflammation in Otitis Media With Effusion. JAMA Otolaryngol Head Neck Surg. 2017;143:810-817 pubmed publisher
    ..4 [95% CI, 1.1-5.6]). A 2-fold increase in MUC5B correlated with increased hearing loss (air-bone gap: 7.45 dB [95% CI, 2.65-12.24 dB]; sound field: 6.66 dB [95% CI, 6.63-6.69 dB]), effusion viscosity (2...
  6. Zaky S, Lee K, Gao J, Jensen A, Verdelis K, Wang Y, et al. Poly (glycerol sebacate) elastomer supports bone regeneration by its mechanical properties being closer to osteoid tissue rather than to mature bone. Acta Biomater. 2017;54:95-106 pubmed publisher
    ..Upon implanting PGS in the rabbit ulna defect, histology and micro-computed tomography analysis showed complete gap bridging with new bone by the PGS elastomer by 8weeks while minimal bone formation was seen in empty controls...
  7. Xiao H, Xiong L, Song X, Jin P, Chen L, Chen X, et al. Angelica sinensis Polysaccharides Ameliorate Stress-Induced Premature Senescence of Hematopoietic Cell via Protecting Bone Marrow Stromal Cells from Oxidative Injuries Caused by 5-Fluorouracil. Int J Mol Sci. 2017;18: pubmed publisher
    ..In addition, gap junction channel protein expression and mediated intercellular communications were attenuated after 5-FU treatment...
  8. Koeppen A, Becker A, Feustel P, Gelman B, Mazurkiewicz J. The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy. J Neurol Sci. 2016;367:171-6 pubmed publisher
    ..The principal components of ICD are fascia adherens junctions (FAJ), desmosomes, and gap junctions...
  9. Pantucek R, Sedláček I, Indráková A, Vrbovská V, Mašlaňová I, Kovařovic V, et al. Staphylococcus edaphicus sp. nov., isolated in Antarctica, harbours mecC gene and genomic islands with suspected role in adaptation to extreme environment. Appl Environ Microbiol. 2017;: pubmed publisher
    ..by multilocus sequence analysis of six housekeeping genes rpoB, hsp60, tuf, dnaJ, gap, and sod MALDI-TOF MS and key biochemical characteristics allowed these bacteria to be distinguished ..

More Information

Publications157 found, 100 shown here

  1. Sarkar D, Singh S. Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43. Andrology. 2017;5:749-762 pubmed publisher
    ..THs also modulate level of gap junctional protein such as connexin 43 (Cx43), a potential regulator of cell proliferation and apoptosis in the ..
  2. Chinsembu K. Plants and other natural products used in the management of oral infections and improvement of oral health. Acta Trop. 2016;154:6-18 pubmed publisher
    ..While the review exposes a dire gap for more studies on clinical efficacy and toxicity, the following emerging trend was noted: basic research on ..
  3. Larabee C, Desai S, Agasing A, Georgescu C, Wren J, Axtell R, et al. Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis. Mol Vis. 2016;22:1503-1513 pubmed
    ..To address this gap in research, we sought to determine how a deficiency in the master antioxidant transcription factor (using nuclear ..
  4. Chang Y, Chang H, Tsai C, Lin H, Ho T, Ye C, et al. Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration. BMC Complement Altern Med. 2017;17:184 pubmed publisher
    ..fruits promote neuron regeneration. A piece of silicone rubber was guided across a 15 mm gap in the sciatic nerve of a rat. This nerve gap was then filled with various doses of Alpinia oxyphylla Miq...
  5. Hutton B, Yazdi F, Bordeleau L, Morgan S, Cameron C, Kanji S, et al. Comparison of physical interventions, behavioral interventions, natural health products, and pharmacologics to manage hot flashes in patients with breast or prostate cancer: protocol for a systematic review incorporating network meta-analyses. Syst Rev. 2015;4:114 pubmed publisher
    ..review and network meta-analysis of randomized studies will synthesize available evidence addressing this knowledge gap. An electronic search of Medline, Embase, AMED, PsycINFO, and the Cochrane Register of Controlled Trials has been ..
  6. Ferrandina G, Palluzzi E, Fanfani F, Gentileschi S, Valentini A, Mattoli M, et al. Endometriosis-associated clear cell carcinoma arising in caesarean section scar: a case report and review of the literature. World J Surg Oncol. 2016;14:300 pubmed
    ..The muscular gap was repaired employing a gore-tex mesh while the external covering was made by a pedicled perforator ..
  7. Heath E, Lynce F, Xiu J, Ellerbrock A, Reddy S, Obeid E, et al. Racial Disparities in the Molecular Landscape of Cancer. Anticancer Res. 2018;38:2235-2240 pubmed
    ..To address this gap in knowledge, we explored the molecular landscape of colorectal cancer (CRC), non-small cell lung cancer (NSCLC) ..
  8. Creppy E, Diallo A, Moukha S, Eklu Gadegbeku C, Cros D. Study of epigenetic properties of Poly(HexaMethylene Biguanide) hydrochloride (PHMB). Int J Environ Res Public Health. 2014;11:8069-92 pubmed publisher
    ..Finally, the status of GAP-junctions (GJIC) in the presence of PHMB has been determined and appeared to not be significantly affected...
  9. Koeppen A, Ramirez R, Becker A, Mazurkiewicz J. Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation. Acta Neuropathol Commun. 2016;4:46 pubmed publisher
    ..excitatory amino acid transporter 1, ATP-sensitive inward rectifier potassium channel 10, and cytosolic ferritin), gap junctions (connexin 43), basement membranes (laminin), mitochondria (ATP synthase subunit beta and frataxin), and ..
  10. Ilekis J, Tsilou E, Fisher S, Abrahams V, Soares M, Cross J, et al. Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Am J Obstet Gynecol. 2016;215:S1-S46 pubmed publisher
    ..pathways in the placenta that are involved in the pathophysiology of pregnancy-related disorders, a significant gap exists in the utilization of this information for the development of new drug therapies to improve pregnancy ..
  11. Alejo A, Matamoros T, Guerra M, Andres G. A Proteomic Atlas of the African Swine Fever Virus Particle. J Virol. 2018;92: pubmed publisher
    ..One such gap regards the composition and structure of the infectious virus particle...
  12. Liu J, Hakucho A, Liu X, Fujimiya T. Acute restraint stress provokes sudden cardiac death in normotensive rats and enhances susceptibility to arrhythmogenic effects of adrenaline in spontaneously hypertensive rats. Leg Med (Tokyo). 2016;21:19-28 pubmed publisher
    ..LVH), we assessed ARS-related incidence of SCD, cardiac and myocardial autonomic nervous system dysfunction, gap junction connexin-43 (Cx43) channel remodeling, and ventricular repolarization abnormality, based on ..
  13. Yang X, Cao X, He P, Li J, Feng M, Zhang Y, et al. Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis. Gastroenterology. 2018;155:1233-1249.e22 pubmed publisher
    ..RACGAP1 promotes proliferation of HCC cells by reducing activation of the Hippo and YAP pathways and promoting cytokinesis in coordination with TPR. ..
  14. Hakimi O, Cameron L. Effect of Exercise on Ovulation: A Systematic Review. Sports Med. 2017;47:1555-1567 pubmed publisher
    ..We believe this merits further investigation in specific cohorts, such as professional athletes. Another gap is the complete absence of exercise-based interventions in anovulatory women with a normal body mass index (BMI)...
  15. Semmens D, Mirabeau O, Moghul I, Pancholi M, Wurm Y, Elphick M. Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution. Open Biol. 2016;6:150224 pubmed publisher
    ..particular interest in this regard because they occupy an 'intermediate' position in animal phylogeny, bridging the gap between the well-studied model protostomian invertebrates (e.g...
  16. Tata B, Huijbregts L, Jacquier S, Csaba Z, Genin E, Meyer V, et al. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse. PLoS Biol. 2014;12:e1001952 pubmed publisher
    ..encodes the synaptic protein rabconnectin-3α, which has been identified as a putative scaffold protein for Rab3-GAP and Rab3-GEP, two regulators of the GTPase Rab3a...
  17. Komati Reddy G, Lindner S, Wendisch V. Metabolic engineering of an ATP-neutral Embden-Meyerhof-Parnas pathway in Corynebacterium glutamicum: growth restoration by an adaptive point mutation in NADH dehydrogenase. Appl Environ Microbiol. 2015;81:1996-2005 pubmed publisher
    ..dehydrogenase (GapN) from Clostridium acetobutylicum, which irreversibly converts glyceraldehyde-3-phosphate (GAP) to 3-phosphoglycerate (3-PG) without generating ATP. As shown recently (S. Takeno, R. Murata, R. Kobayashi, S...
  18. Shah M, Brownlee M. Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes. Circ Res. 2016;118:1808-29 pubmed publisher
    ..Mitochondrial oxidative stress also plays a central role in angiotensin II-induced gap junction remodeling and arrhythmogenesis...
  19. Grantz K, Hediger M, Liu D, Buck Louis G. Fetal growth standards: the NICHD fetal growth study approach in context with INTERGROWTH-21st and the World Health Organization Multicentre Growth Reference Study. Am J Obstet Gynecol. 2018;218:S641-S655.e28 pubmed publisher
    ..morbidity and mortality using different criteria is necessary to make recommendations and remains an important data gap. Identification of the appropriate percentile cutoffs in relation to neonatal morbidity and mortality is needed in ..
  20. Algarrahi K, Franck D, Ghezzi C, Cristofaro V, Yang X, Sullivan M, et al. Acellular bi-layer silk fibroin scaffolds support functional tissue regeneration in a rat model of onlay esophagoplasty. Biomaterials. 2015;53:149-59 pubmed publisher
    Surgical management of long-gap esophageal defects with autologous gastrointestinal tissues is frequently associated with adverse complications including organ dysmotility, dysphagia, and donor site morbidity...
  21. Garimella R, Tadikonda P, Tawfik O, Gunewardena S, Rowe P, Van Veldhuizen P. Vitamin D Impacts the Expression of Runx2 Target Genes and Modulates Inflammation, Oxidative Stress and Membrane Vesicle Biogenesis Gene Networks in 143B Osteosarcoma Cells. Int J Mol Sci. 2017;18: pubmed publisher
    ..of reactive oxygen species, metabolism of cyclic nucleotides, sterols, vitamins and mineral (calcium), quantity of gap junctions and skeletogenesis; (c) bone mineral density; and (d) cell viability of skeletal cells, aggregation of ..
  22. Wu Y, Chang H, Huang H, Sheng J, Leung P. Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells. Mol Hum Reprod. 2017;23:155-165 pubmed publisher
    ..regulate connexin43 (Cx43) and modulate cell-cell communication in luteinized human granulosa cells? BMP2 decreases gap junction intercellular communication (GJIC) of luteinized human granulosa cells by down-regulating Cx43 expression ..
  23. Chen Y, Shi S, Wang H, Li N, Su J, Chou G, et al. A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells. Int J Mol Sci. 2016;17: pubmed publisher
    ..SCP-0-1 inhibited the HepG2 cells' growth via inducing apoptosis and second gap/mitosis (G2/M) arrest dose-dependently, with a half maximal inhibitory concentration (IC50) value of 479.63 µg/mL...
  24. Kocyigit D, Tokgozoglu L, Kayikcioglu M, Altay S, Aydogdu S, Barcin C, et al. Is there a gender gap in secondary prevention of coronary artery disease in Turkey?. Turk Kardiyol Dern Ars. 2018;46:683-691 pubmed publisher
    ..This highlights the importance of the implementation of lifestyle measures and adherence to medications in women. ..
  25. Paredes J, Herren J, Schüpfer F, Marin R, Claverol S, Kuo C, et al. Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont. MBio. 2015;6: pubmed publisher
    ..This work fills a gap in our knowledge of insect endosymbionts and provides tools with which to decipher the interaction between ..
  26. Liu X, Tao Y, Wang F, Yao T, Fu C, Zheng H, et al. Kudiezi injection mitigates myocardial injury induced by acute cerebral ischemia in rats. BMC Complement Altern Med. 2017;17:8 pubmed publisher
    ..Myocardial ischemic changes (widened myocardial cell gap, cracks, and obvious edema) were detected in the 6h-ischemia group compared with the sham group, with elevated ..
  27. Looser V, Brühlmann B, Bumbak F, Stenger C, Costa M, Camattari A, et al. Cultivation strategies to enhance productivity of Pichia pastoris: A review. Biotechnol Adv. 2015;33:1177-93 pubmed publisher
    ..rates, μ, has been analysed in a conceptual attempt to compare different systems, particularly those based on AOX1/methanol and GAP/glucose, and this has now evolved into a pivotal concept for bioprocess engineering of P. pastoris.
  28. Wang Y, Li Z, Xian Y, Zhao X, Li H, Shen H, et al. Rationale and design of a cluster-randomized multifaceted intervention trial to improve stroke care quality in China: The GOLDEN BRIDGE-Acute Ischemic Stroke. Am Heart J. 2015;169:767-774.e2 pubmed publisher
    Prior studies have demonstrated a significant gap between guideline-based recommendations and clinical practice in the management of acute ischemic stroke (AIS) in China...
  29. Golmard L, Delnatte C, Laugé A, Moncoutier V, Lefol C, Abidallah K, et al. Breast and ovarian cancer predisposition due to de novo BRCA1 and BRCA2 mutations. Oncogene. 2016;35:1324-7 pubmed publisher
    ..The present study was designed to fill this gap based on a series of 12 805 consecutive unrelated patients diagnosed with breast and/or ovarian cancer who ..
  30. Caputo N, Kanter M, Fraser R, Simon R. Comparing biomarkers of traumatic shock: the utility of anion gap, base excess, and serum lactate in the ED. Am J Emerg Med. 2015;33:1134-9 pubmed publisher
    Biomarkers such as serum lactate, anion gap (AG), and base excess (BE) have been shown to be of use in determining shock in patients with seemingly normal vital signs...
  31. Andersen M, Landes X, Xiang W, Anyshchenko A, Falhof J, Østerberg J, et al. Feasibility of new breeding techniques for organic farming. Trends Plant Sci. 2015;20:426-34 pubmed publisher
    ..Ideally, the goal should be to narrow this yield gap. In this review, we specifically discuss the feasibility of new breeding techniques (NBTs) for rewilding, a process ..
  32. Burns H. Health inequalities - why so little progress?. Public Health. 2015;129:849-53 pubmed publisher
    ..The deeper insights obtained from comprehensive analysis have prompted new approaches to narrowing the gap. Opportunities for well-being are created within the complex system of a well functioning society and novel methods ..
  33. Van Hemelen G, Van Genechten M, Renier L, Desmedt M, Verbruggen E, Nadjmi N. Three-dimensional virtual planning in orthognathic surgery enhances the accuracy of soft tissue prediction. J Craniomaxillofac Surg. 2015;43:918-25 pubmed publisher
    Throughout the history of computing, shortening the gap between the physical and digital world behind the screen has always been strived for...
  34. Marzilli C. Assessment of cultural competence in Texas nursing faculty. Nurse Educ Today. 2016;45:225-9 pubmed publisher
    Cultural competence [CC] is an essential component of nursing education and nursing practice yet there is a gap in the research evaluating CC in faculty and how to practically develop this skillset for faculty members...
  35. Chen J, Zhu Y, Liang C, Chen J, Zhao H. Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing. Sci Rep. 2015;5:10762 pubmed publisher
    Pannexin1 (Panx1) is a gap junction gene in vertebrates whose proteins mainly function as non-junctional channels on the cell surface...
  36. Huang Y, Choi H, Kushida Y, Bhayana B, Wang Y, Hamblin M. Broad-Spectrum Antimicrobial Effects of Photocatalysis Using Titanium Dioxide Nanoparticles Are Strongly Potentiated by Addition of Potassium Iodide. Antimicrob Agents Chemother. 2016;60:5445-53 pubmed publisher
    Photocatalysis describes the excitation of titanium dioxide nanoparticles (a wide-band gap semiconductor) by UVA light to produce reactive oxygen species (ROS) that can destroy many organic molecules...
  37. Heileman K, Daoud J, Tabrizian M. Elaboration of a finite element model of pancreatic islet dielectric response to gap junction expression and insulin release. Colloids Surf B Biointerfaces. 2016;148:474-480 pubmed publisher
    ..the simulation showed that both exocytosis, such as what occurs during insulin secretion, and differential gap junction expression have significant effects on islet dielectric response...
  38. Boudreau S, Kamavuako E, Rathleff M. Distribution and symmetrical patellofemoral pain patterns as revealed by high-resolution 3D body mapping: a cross-sectional study. BMC Musculoskelet Disord. 2017;18:160 pubmed publisher
    ..This study highlights a gap in knowledge of PFP symptom presentation, reveals what may be a natural progression of symptoms, and provides ..
  39. Min K, Kim S, Kim S. Deformable and conformal silk hydrogel inverse opal. Proc Natl Acad Sci U S A. 2017;114:6185-6190 pubmed publisher
    ..The pseudophotonic band gap (pseudo-PBG) of this material can be stably tuned by deformation of the photonic lattice (stretching, bending, and ..
  40. Lin W, Lin Y, Wang Y. A decision-making approach for delineating sites which are potentially contaminated by heavy metals via joint simulation. Environ Pollut. 2016;211:98-110 pubmed publisher
    ..Finally, Info-Gap Decision Theory (IGDT) is used to consider different monitoring and or remediation regimes based on the analysis of ..
  41. Casado Medrano V, Barrio Real L, Garcia Rostan G, Baumann M, Rocks O, Caloca M. A new role of the Rac-GAP ?2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression. Oncotarget. 2016;7:28301-19 pubmed publisher
    ..Overall, our data redefine the role of ?2-chimaerin as tumor suppressor and provide the first in vivo evidence of a dual function in breast cancer, suppressing tumor initiation but favoring tumor progression. ..
  42. Angus S, Vu T, Willett L, Call S, Halvorsen A, Chaudhry S. Internal Medicine Residency Program Directors' Views of the Core Entrustable Professional Activities for Entering Residency: An Opportunity to Enhance Communication of Competency Along the Continuum. Acad Med. 2017;92:785-791 pubmed publisher
    ..which Core EPAs new interns must or should possess on day 1, which are most essential, and which have the largest gap between expected and observed performance...
  43. Coleman J, Lin B, Schwob J. Dissecting LSD1-Dependent Neuronal Maturation in the Olfactory Epithelium. J Comp Neurol. 2017;525:3391-3413 pubmed publisher
    ..To fill this gap, the present study determined that LSD1 (1) is expressed in early dividing cells before OR expression and neuronal ..
  44. Fox A, Shackman A. The central extended amygdala in fear and anxiety: Closing the gap between mechanistic and neuroimaging research. Neurosci Lett. 2017;: pubmed publisher
    ..perturbations and whole-brain imaging, a new generation of nonhuman primate studies is beginning to close this gap. This work opens the door to discovering the mechanisms underlying neuroimaging measures linked to pathological ..
  45. Yap H, Fung S, Ng S, Tan C, Tan N. Shotgun proteomic analysis of tiger milk mushroom (Lignosus rhinocerotis) and the isolation of a cytotoxic fungal serine protease from its sclerotium. J Ethnopharmacol. 2015;174:437-51 pubmed publisher
    ..This study aims to bridge the gap in existing research literature by using proteomics approach for investigation of the nature of the anticancer ..
  46. McLean K, Goldin S, Nannei C, Sparrow E, Torelli G. The 2015 global production capacity of seasonal and pandemic influenza vaccine. Vaccine. 2016;34:5410-5413 pubmed publisher
    ..The Global Action Plan for Influenza Vaccines (GAP) was launched in 2006 to increase global capacity for influenza vaccine production to address these concerns...
  47. Araki M, Bandi M, Yazaki Sugiyama Y. Mind the gap: Neural coding of species identity in birdsong prosody. Science. 2016;354:1282-1287 pubmed
    ..Behavioral learning and neuronal coding of temporal gap structure resisted song tutoring from other species: Zebra finches fostered by Bengalese finch parents learned ..
  48. Bauer U, Helm P, Diller G, Asfour B, Schlensak C, Schmitt K, et al. Are adults with congenital heart disease informed about their risk for infective endocarditis and treated in accordance to current guidelines?. Int J Cardiol. 2017;245:105-108 pubmed publisher
    ..A discussion about IE and antibiotic prophylaxis should take place with every ACHD patient during regular clinical contacts to close this knowledge gap.
  49. Smets G, Rüdelsheim P. Biotechnologically produced chitosan for nanoscale products. A legal analysis. N Biotechnol. 2018;42:42-47 pubmed publisher
    ..While a knowledge gap exists on hazards related to nanomaterials in general, there is a need to establish realistic regulatory study ..
  50. Riva B, Bellini M, Corvi E, Verderio P, Rozek E, Colzani B, et al. Impact of the strategy adopted for drug loading in nonporous silica nanoparticles on the drug release and cytotoxic activity. J Colloid Interface Sci. 2018;519:18-26 pubmed publisher
    ..To help filling the gap of a poor clinical translation of hard nanoparticles, we have designed and developed three different nonporous ..
  51. Chamizo E, López Lora M, Bressac M, Levy I, Pham M. Excess of (236)U in the northwest Mediterranean Sea. Sci Total Environ. 2016;565:767-776 pubmed publisher
    ..and the radioactive effluents produced by the different nuclear installations allocated to the Mediterranean basin, might explain the inventory gap, however, further studies are necessary to come to a conclusion about its origin.
  52. Buntaine A, Shah B, Lorin J, Sedlis S. Revascularization Strategies in Patients with Diabetes Mellitus and Acute Coronary Syndrome. Curr Cardiol Rep. 2016;18:79 pubmed publisher
    ..This potentially narrowed that gap between CABG and PCI requires further investigation.
  53. Huang S, Zhang N, Zhou Z, Huang C, Zeng C, Xiao D, et al. Association of LPP and TAGAP Polymorphisms with Celiac Disease Risk: A Meta-Analysis. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..Prospective studies and more genome-wide association studies (GWAS) are needed to confirm these findings, and some corresponding molecular biology experiments should be carried out to clarify the pathogenic mechanisms of celiac disease. ..
  54. Mutlu A, Topdağ Ö, Topdağ M, Iseri M, Erdogan S. A Comparison Study of Partial Ossicular Reconstruction Prosthesis (PORP) Placement under the Malleus or Tympanic Membrane Graft in the Presence of the Malleus. J Int Adv Otol. 2017;13:200-203 pubmed publisher
    ..Pre- and postoperative audiometric results were assessed. The air-bone gap (ABG) and hearing gains were evaluated according to the groups. In MASH, 86...
  55. Liu H, Zhai H, Hu C, Yang J, Liu Z. Hydrothermal synthesis of In2O3 nanoparticles hybrid twins hexagonal disk ZnO heterostructures for enhanced photocatalytic activities and stability. Nanoscale Res Lett. 2017;12:466 pubmed publisher
    ..Due to suitable alignment of their energy band-gap structure of the In2O3 and ZnO, the formation of type ? heterostructure can enhance efficient ..
  56. McDonald M, Ashley E, Fedak P, Hawkins N, Januzzi J, McMurray J, et al. Mind the Gap: Current Challenges and Future State of Heart Failure Care. Can J Cardiol. 2017;33:1434-1449 pubmed publisher
    ..This review highlights key challenges in the management of HF and highlights the progress toward an ideal future state. ..
  57. Hudak S, Overkamp D, Wagner R, Häring H, Heni M. Ketoacidosis in a non-diabetic woman who was fasting during lactation. Nutr J. 2015;14:117 pubmed publisher
    ..Blood gas analysis showed a severe metabolic acidosis with a high anion gap. Further workup revealed the presence of ketone bodies in the urine with normal blood glucose and no history of ..
  58. Ahmed S, Rahman A, Hassan M, Salih S, Paone M, Cecchi G. An atlas of tsetse and bovine trypanosomosis in Sudan. Parasit Vectors. 2016;9:194 pubmed publisher
    ..The Atlas of tsetse and bovine trypanosomosis in Sudan tries to fill this gap. The present study includes both a review of historical datasets on tsetse flies and bovine trypanosomosis, as well ..
  59. Peng R, Li D. Detection and sizing of nanoparticles and DNA on PDMS nanofluidic chips based on differential resistive pulse sensing. Nanoscale. 2017;9:5964-5974 pubmed publisher
    ..acquisition, and a straight nanochannel on the bottom layer fabricated by an unconventional approach bridging the gap between the microchannels works as an RPS sensing gate...
  60. Masuda M, Fujita M, Iida O, Okamoto S, Ishihara T, Nanto K, et al. Association Between Local Bipolar Voltage and Conduction Gap Along the Left Atrial Linear Ablation Lesion in Patients With Atrial Fibrillation. Am J Cardiol. 2017;120:408-413 pubmed publisher
    ..The purpose of this study was to explore the association between local bipolar voltage and conduction gap in patients with persistent atrial fibrillation (AF) who underwent atrial roof or septal linear ablation...
  61. Whyte Fagundes P, Zoidl G. Mechanisms of pannexin1 channel gating and regulation. Biochim Biophys Acta Biomembr. 2018;1860:65-71 pubmed publisher
    ..This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve.
  62. Sim L, Tan W, Leong K, Bashir M, Saravanan P, Surib N. Mechanistic Characteristics of Surface Modified Organic Semiconductor g-C₃N₄ Nanotubes Alloyed with Titania. Materials (Basel). 2017;10: pubmed publisher
    ..16 times higher than the pure HT-g-C₃N₄. The enhanced photocatalytic activity was mainly due to the promising optical band gap structure with heterojunction interface, favorable specific surface area, and good charge separation.
  63. Allegaert K. Better medicines for neonates: Improving medicine development, testing, and prescribing. Early Hum Dev. 2017;114:22-25 pubmed publisher
    ..Clinical researchers will be crucial to close the knowledge gap by developing dose selection tools and outcome assessment tools and by exploring pathophysiological mechanisms...
  64. Sundman A, Byrne J, Bauer I, Menguy N, Kappler A. Interactions between magnetite and humic substances: redox reactions and dissolution processes. Geochem Trans. 2017;18:6 pubmed publisher
    ..To address this knowledge gap, we incubated non-reduced (native) and reduced HS with four types of magnetite that varied in particle size and ..
  65. van der Lee R, Ellemers N. Gender contributes to personal research funding success in The Netherlands. Proc Natl Acad Sci U S A. 2015;112:12349-53 pubmed publisher
    ..Overall, our data reveal a 4% "loss" of women during the grant review procedure, and illustrate the perpetuation of the funding gap, which contributes to the underrepresentation of women in academia.
  66. Yoshizawa K, Lienhard C. Bridging the gap between chewing and sucking in the hemipteroid insects: <br />new insights from Cretaceous amber. Zootaxa. 2016;4079:229-45 pubmed publisher
    ..A phylogenetic analysis that includes Mydiognathus strongly supports the monophyly of the Paraneoptera. ..
  67. Ngui E, Greer D, Bridgewater F, Salm Ward T, Cisler R. Trends and Progress in Reducing Teen Birth Rates and the Persisting Challenge of Eliminating Racial/Ethnic Disparities. J Racial Ethn Health Disparities. 2017;4:615-622 pubmed publisher
    ..The gap between white and both black and Hispanic/Latina teens widened...
  68. Hoffman A, Brintnall R. A Home-based Exercise Intervention for Non-Small Cell Lung Cancer Patients Post-Thoracotomy. Semin Oncol Nurs. 2017;33:106-117 pubmed publisher
    ..effective postsurgical exercise intervention targeting the self-management of cancer-related fatigue to fill this gap. Qualitative perspective of 37 individuals randomized to a 6-week exercise program following hospital discharge ..
  69. Decrock E, Hoorelbeke D, Ramadan R, Delvaeye T, De Bock M, Wang N, et al. Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?. Biochim Biophys Acta Mol Cell Res. 2017;1864:1099-1120 pubmed publisher
    ..A substantial amount of evidence is available demonstrating that both gap junctional and paracrine communication pathways can propagate radiation-induced biological effects at the ..
  70. Mohanta D, Barman K, Jasimuddin S, Ahmaruzzaman M. MnO doped SnO2 nanocatalysts: Activation of wide band gap semiconducting nanomaterials towards visible light induced photoelectrocatalytic water oxidation. J Colloid Interface Sci. 2017;505:756-762 pubmed publisher
    Semiconducting nanomaterials are very important by means of their stability and wide band gap tunability...
  71. Ushak S, Cruz M, Cabeza L, Grágeda M. Preparation and Characterization of Inorganic PCM Microcapsules by Fluidized Bed Method. Materials (Basel). 2016;9: pubmed publisher
    ..materials (PCM) have been very seldom microencapsulated, so this study aims to contribute to filling this research gap. Bischofite, a by-product from the non-metallic industry identified as having good potential to be used as ..
  72. Sankar R, G P, Irulandi P, Xu S, Hasan M, Chou F. Crystal growth and transport properties of Weyl semimetal TaAs. J Phys Condens Matter. 2017;: pubmed publisher
    ..dependent resistivity measurements at different static magnetic fields suggest the formation of an insulating gap in a Weyl semimetal TaAs...
  73. Houy S, Estay Ahumada C, Croisé P, Calco V, Haeberlé A, Bailly Y, et al. Oligophrenin-1 Connects Exocytotic Fusion to Compensatory Endocytosis in Neuroendocrine Cells. J Neurosci. 2015;35:11045-55 pubmed publisher
    Oligophrenin-1 (OPHN1) is a protein with multiple domains including a Rho family GTPase-activating (Rho-GAP) domain, and a Bin-Amphiphysin-Rvs (BAR) domain...
  74. Wang R, Zhang X, Wang S, Fu G, Wang J. Flatbands in 2D boroxine-linked covalent organic frameworks. Phys Chem Chem Phys. 2016;18:1258-64 pubmed publisher
    ..For boroxine-linked COFs with only one benzene ring in the branch, the band gap is robust under compressive strain while it decreases with the tensile strain increasing...
  75. Loerbroks A, Weigl M, Li J, Angerer P. Effort-reward imbalance and perceived quality of patient care: a cross-sectional study among physicians in Germany. BMC Public Health. 2016;16:342 pubmed publisher
    ..Further, to address another research gap and to potentially inform the development of better-targeted interventions, we aimed to examine associations of ..
  76. Adachi J, Inaba Y, Maki C. Euglycemic Diabetic Ketoacidosis with Persistent Diuresis Treated with Canagliflozin. Intern Med. 2017;56:187-190 pubmed publisher
    Diabetic ketoacidosis is characterized by hyperglycemia, anion-gap acidosis, and increased plasma ketones. After the resolution of hyperglycemia, persistent diuresis is rare...
  77. Kozono N, Okada T, Takeuchi N, Shimoto T, Higaki H, Nakashima Y. Effect of the Optimal Asymmetry on the Strength of Six-Strand Tendon Repair: An Ex Vivo Biomechanical Study. J Hand Surg Am. 2017;42:250-256 pubmed publisher
    ..with 3 mm or more asymmetry in suture purchases in 2 tendon ends generated increased fatigue strength and reduced gap sizes compared with those with symmetric suture placement in an ex vivo porcine model...
  78. Richardson E, Moon G, Pearce J, Shortt N, Mitchell R. Multi-scalar influences on mortality change over time in 274 European cities. Soc Sci Med. 2017;179:45-51 pubmed publisher
    ..SMRs declined over time and the substantial East-West gap narrowed slightly...
  79. Houghton A, Austin J, Beerman A, Horton C. An Approach to Developing Local Climate Change Environmental Public Health Indicators in a Rural District. J Environ Public Health. 2017;2017:3407325 pubmed publisher
    ..This article fills a gap in public health practice by developing climate and health environmental public health indicators for a local ..
  80. Ruffini L, Lauretani F, Scarlattei M, Ticinesi A, Meschi T, Ghetti C, et al. Integrating Information from FDG - and Amyloid PET for Detecting Different Types of Dementia in Older Persons. A Case-series Study. J Prev Alzheimers Dis. 2016;3:127-132 pubmed publisher
    ..Neuroimaging, including positron emission tomography (PET) and magnetic resonance, could help to bridge the gap by providing in vivo information about disease staging...
  81. Sarjan H, Yajurvedi H. Chronic stress induced duration dependent alterations in immune system and their reversibility in rats. Immunol Lett. 2018;197:31-43 pubmed publisher
    ..male rats (n = 30) were subjected to restraint (1 h) followed by forced swimming exercise (15 min) after a gap of 4 h daily for 2, 4 and 8 weeks and allowed to recover for 6 weeks after each exposure period...
  82. Pore S, Ramanand S, Patil P, Gore A, Pawar M, Gaidhankar S, et al. A retrospective study of use of polyvalent anti-snake venom and risk factors for mortality from snake bite in a tertiary care setting. Indian J Pharmacol. 2015;47:270-4 pubmed publisher
    ..Association of various risk factors (age, gender, dose of ASV, time gap between snake bite and ASV administration, use of mechanical ventilation and type of snake bite) with mortality was ..
  83. Patterson V, Singh M, Rajbhandari H, Vishnubhatla S. Validation of a phone app for epilepsy diagnosis in India and Nepal. Seizure. 2015;30:46-9 pubmed publisher
    ..It needs to be evaluated more widely but has the potential to play a part in reducing the epilepsy treatment gap.
  84. Guo Y, Qiu X, Dong H, Zhou X. Trends in non-metal doping of the SrTiO₃ surface: a hybrid density functional study. Phys Chem Chem Phys. 2015;17:21611-21 pubmed publisher
    ..Due to the appearance of surface O 2p states, the band gap of the pure TiO2-terminated surface is calculated to be 2.56 eV, which is much narrower than that of bulk SrTiO3 (3...
  85. Cao T, Wang D, Geng D, Liu L, Zhao J. A strain or electric field induced direct bandgap in ultrathin silicon film and its application in photovoltaics or photocatalysis. Phys Chem Chem Phys. 2016;18:7156-62 pubmed publisher
    ..The results demonstrate that all USFs are indirect band-gap semiconductors; interestingly, tensile strain or electric field efficiently tunes the USFs into direct band gap ..
  86. Qi M, Zhu X, Du W, Chen Y, Chen Y, Huang T, et al. Exposure and health impact evaluation based on simultaneous measurement of indoor and ambient PM2.5 in Haidian, Beijing. Environ Pollut. 2017;220:704-712 pubmed publisher
    ..Unfortunately, indoor air data are scarce, leading to a major data gap in risk assessment. In this study, PM2...
  87. Liang B, Tan Y, Li Z, Tian X, Du C, Li H, et al. Highly Sensitive Detection of Isoniazid Heteroresistance in Mycobacterium tuberculosis by DeepMelt Assay. J Clin Microbiol. 2018;56: pubmed publisher
    ..The DeepMelt assay may fill the gap between current genotypic and phenotypic drug susceptibility testing for detecting drug-resistant tuberculosis ..
  88. Jia J, Li J, Jiang L, Lin B, Wang L, Su R, et al. Liver protection strategies in liver transplantation. Hepatobiliary Pancreat Dis Int. 2015;14:34-42 pubmed
    Liver transplantation is the therapy of choice for patients with end-stage liver diseases. However, the gap between the low availability of organs and high demand is continuously increasing...
  89. Muñoz Tamayo R, Puillet L, Daniel J, Sauvant D, Martin O, Taghipoor M, et al. Review: To be or not to be an identifiable model. Is this a relevant question in animal science modelling?. Animal. 2017;:1-12 pubmed publisher
    ..To fill this gap, in this paper we address the analysis of structural identifiability from a practitioner perspective by ..
  90. Spengler C, Thewes N, Jung P, Bischoff M, Jacobs K. Determination of the nano-scaled contact area of staphylococcal cells. Nanoscale. 2017;9:10084-10093 pubmed publisher
    ..So far, less is known about the size of the contact area between bacterial cells and a surface. This gap will be filled by this study using a single-cell force spectroscopy-based method to investigate the contact area ..
  91. Ma X, Wu X, Zhao X, Sun H. Geometric and electronic properties of ultrathin anatase TiO2(001) films. Phys Chem Chem Phys. 2017;19:25456-25462 pubmed publisher
    ..It is interesting to find that the lattice parameters, intertrilayer distances, electronic band gap and the position of the valence band edge for the films depend strongly on the number of trilayers, and they ..
  92. Shrubsole K, Worrall L, Power E, O Connor D. Priorities for Closing the Evidence-Practice Gaps in Poststroke Aphasia Rehabilitation: A Scoping Review. Arch Phys Med Rehabil. 2018;99:1413-1423.e24 pubmed publisher
    ..criteria were identified in the implementation literature: strength of the evidence, current evidence-practice gap, clinician preference, patient preference, modifiability, measurability, and health effect...