Gene Symbol: RAB30
Description: RAB30, member RAS oncogene family
Alias: ras-related protein Rab-30
de Leeuw H, Koster P, Calafat J, Janssen H, van Zonneveld A, Van Mourik J, et al
. Small GTP-binding proteins in human endothelial cells. Br J Haematol. 1998;103:15-9 pubmed
..function of the different small GTP-binding proteins identified we have isolated full length cDNA corresponding to Rab30 from a human endothelial cell cDNA library...
Kelly E, Giordano F, Horgan C, Jollivet F, Raposo G, McCaffrey M. Rab30 is required for the morphological integrity of the Golgi apparatus. Biol Cell. 2012;104:84-101 pubmed publisher
..Many Rabs have been extensively characterised whereas others, such as Rab30, have to date received relatively little attention.
Gillingham A, Sinka R, Torres I, Lilley K, Munro S. Toward a comprehensive map of the effectors of rab GTPases. Dev Cell. 2014;31:358-73 pubmed publisher
..We confirm over 25 interactions for Rab2, Rab4, Rab5, Rab6, Rab7, Rab9, Rab18, Rab19, Rab30, and Rab39...
Puvar K, Iyer S, Sheedlo M, Das C. Purification and functional characterization of the DUB domain of SdeA. Methods Enzymol. 2019;618:343-355 pubmed publisher
..Several mammalian Rab proteins (Rab1, Rab30, and Rab33) have been shown to be targeted...
Oda S, Nozawa T, Nozawa Minowa A, Tanaka M, Aikawa C, Harada H, et al
. Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes. PLoS ONE. 2016;11:e0147061 pubmed publisher
..Here, we identified Rab30 as a novel regulator of GAS-containing autophagosome-like vacuoles (GcAVs)...
Holliday E, Smith A, Cornes B, Buitendijk G, Jensen R, Sim X, et al
. Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS ONE. 2013;8:e53830 pubmed publisher
Romano J, Sonda S, Bergbower E, Smith M, Coppens I. Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole. Mol Biol Cell. 2013;24:1974-95 pubmed publisher
..These vesicles, marked with Rab14, Rab30, or Rab43, colocalize with host-derived sphingolipids in the vacuolar space...
Chen D, Guo J, Miki T, Tachibana M, Gahl W. Molecular cloning of two novel rab genes from human melanocytes. Gene. 1996;174:129-34 pubmed
..One gene, rab30 codes for a novel rab protein of 203 amino acids with minimal homology to previously documented GTPases...
Régnier M, Polizzi A, Lippi Y, Fouché E, Michel G, Lukowicz C, et al
. Insights into the role of hepatocyte PPARα activity in response to fasting. Mol Cell Endocrinol. 2018;471:75-88 pubmed publisher
..Interestingly, we identified novel PPARα-sensitive genes, including Cxcl-10, Rab30, and Krt23...