PRPF6

Summary

Gene Symbol: PRPF6
Description: pre-mRNA processing factor 6
Alias: ANT-1, ANT1, C20orf14, Prp6, RP60, SNRNP102, TOM, U5-102K, hPrp6, pre-mRNA-processing factor 6, PRP6 homolog, PRP6 pre-mRNA processing factor 6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein, androgen receptor N-terminal domain transactivating protein-1, p102 U5 small nuclear ribonucleoprotein particle-binding protein
Species: human
Products:     PRPF6

Top Publications

  1. Ramirez Estrada K, Castillo N, Lara J, Arró M, Boronat A, Ferrer A, et al. Tomato UDP-Glucose Sterol Glycosyltransferases: A Family of Developmental and Stress Regulated Genes that Encode Cytosolic and Membrane-Associated Forms of the Enzyme. Front Plant Sci. 2017;8:984 pubmed publisher
    ..Micro-Tom) SGT gene family. Expression of recombinant SlSGT proteins in E. coli cells and N...
  2. Feng X, Li H, Dean M, Wilson H, Kornaga E, Enwere E, et al. Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer. Breast Cancer Res. 2015;17:65 pubmed publisher
    ..resected tumors from two cohorts of patients (HPBC cohort: n=130; HNBC cohort: n=168) diagnosed at the Tom Baker Cancer Centre, Calgary, Canada, were analyzed for ATM protein expression using fluorescence ..
  3. Tang W, Hu Y, He X. [Acupuncture Stimulation of Acupoints of Multiple Meridians for Patients with Diminished Ovarian Reserve of Both Yin and Yang Deficiency]. Zhen Ci Yan Jiu. 2015;40:479-83, 488 pubmed
    ..4%) and 6 (12.5%) failed, with the effective rate being 89.6% and 87.5%, respectively. The integral score of TOM symptoms, menstrual cycle, serum FSH, LH and E2 contents were considerably diminished in both groups after 6 months ..
  4. Pompeu G, Vilhena M, Gratão P, Carvalho R, Rossi M, Martinelli A, et al. Abscisic acid-deficient sit tomato mutant responses to cadmium-induced stress. Protoplasma. 2017;254:771-783 pubmed publisher
    ..aimed to characterize the biochemical response and ultrastructural changes induced by cadmium (Cd) in the Micro-Tom (MT) sitiens ABA-deficient mutant (sit) and its wild-type (MT) counterpart...
  5. Hundal J, Wadhwa M, Bakshi M. Herbal feed additives containing essential oil: 1. Impact on the nutritional worth of complete feed in vitro. Trop Anim Health Prod. 2019;: pubmed publisher
    ..TMR with different HFAs did not affect the digestibility of neutral detergent fiber (NDF) and true organic matter (TOM) and partitioning factor (PF). The total volatile fatty acids (VFAs), acetate, propionate (P < 0...
  6. Sunde R, Sunde G, Sunde C, Sunde M, Evenson J. Cloning, Sequencing, and Expression of Selenoprotein Transcripts in the Turkey (Meleagris gallopavo). PLoS ONE. 2015;10:e0129801 pubmed publisher
    ..Total RNA was isolated from six tissues of Se-adequate adult tom turkeys, and used to prepare reverse-transcription cDNA libraries...
  7. Pei H, Hou J, Wei F, Xue Q, Zhang F, Peng C, et al. Melatonin attenuates postmyocardial infarction injury via increasing Tom70 expression. J Pineal Res. 2017;62: pubmed publisher
    ..As a receptor for translocases in the outer mitochondrial membrane (Tom) complex, Tom70 has an unknown function in MI, including melatonin-induced protection against MI injury...
  8. Huang S, Nie S, Wang S, Liu J, Zhang Y, Wang X. SlBIR3 Negatively Regulates PAMP Responses and Cell Death in Tomato. Int J Mol Sci. 2017;18: pubmed publisher
    ..We observed that SlBIR3 overexpression in tomato (cv. micro-tom) and A. thaliana has weak effect on growth and development through brassinosteroid (BR) signaling...
  9. Stepovaya E, Shakhristova E, Nosareva O, Rudikov E, Egorova M, Egorova D, et al. [Redox-dependent mechanisms of regulation of breast epithelial cell proliferation]. Biomed Khim. 2017;63:159-164 pubmed publisher
    ..Aktivatsiia svobodnoradikal'nogo okisleniia v razlichnykh tipakh kletok, v tom chisle kletkakh épiteliia molochno? zhelezy, sposobna privodit' k povrezhdeniiu makromolekul, v chastnosti belkov, ..

More Information

Publications98

  1. Leme D, Visacre E, Castro V, Lopes M. Testicular cytology by fine needle aspiration in domestic cats. Theriogenology. 2018;106:46-52 pubmed publisher
    In cases where semen collection in tom-cats is not possible, FNA of testes is the alternative to evaluate sperm production...
  2. Adadi P, Barakova N, Muravyov K, Krivoshapkina E. Designing selenium functional foods and beverages: A review. Food Res Int. 2019;120:708-725 pubmed publisher
    ..Pasteurized dried selenized supplements (yeast and algae) were proposed in formulating Selenized enriched Tom-brown. This review seeks to propose some possible foods that could be enriched with Se...
  3. Ryans K, Omosun Y, McKeithen D, Simoneaux T, Mills C, Bowen N, et al. The immunoregulatory role of alpha enolase in dendritic cell function during Chlamydia infection. BMC Immunol. 2017;18:27 pubmed publisher
    ..compared to the Chlamydia-pulsed WT DCs was associated with the dysregulation of translocase of the outer membrane (TOM) 20 and adenine nucleotide translocator (ANT) 1/2/3/4 that regulate mitochondrial permeability...
  4. De R, Mazumder S, Sarkar S, Debsharma S, Siddiqui A, Saha S, et al. Acute mental stress induces mitochondrial bioenergetic crisis and hyper-fission along with aberrant mitophagy in the gut mucosa in rodent model of stress-related mucosal disease. Free Radic Biol Med. 2017;113:424-438 pubmed publisher
    ..and PINK1 along with enhanced mitochondrial proteome ubiquitination, depletion of mitochondrial DNA copy number and TOM 20...
  5. Lynn E, Stevens M, Wong R, Carabenciov D, Jacobson J, Murphy E, et al. Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1. J Mol Cell Cardiol. 2010;49:693-8 pubmed publisher
    ..gene array analysis showed a 3-fold PGC-1alpha-mediated upregulation of adenine nucleotide translocase 1 (ANT1)...
  6. Schwalbe E, Lindsey J, Nakjang S, Crosier S, Smith A, Hicks D, et al. Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study. Lancet Oncol. 2017;18:958-971 pubmed publisher
    ..These data provide a new foundation for future research and clinical investigations. Cancer Research UK, The Tom Grahame Trust, Star for Harris, Action Medical Research, SPARKS, The JGW Patterson Foundation, The INSTINCT network ..
  7. Small B, Lu Y, Hsu A, Gross G, Gross E. Morphine Reduces Myocardial Infarct Size via Heat Shock Protein 90 in Rodents. Biomed Res Int. 2015;2015:129612 pubmed publisher
    ..These data suggest that opioid-induced cardioprotection is mediated by HSP90. Part of this protection afforded by HSP90 is downstream of GSK3β, potentially via the HSP-TOM mitochondrial import pathway.
  8. El Radaideh N, Al Taani A, Al Khateeb W. Characteristics and quality of reservoir sediments, Mujib Dam, Central Jordan, as a case study. Environ Monit Assess. 2017;189:143 pubmed publisher
    ..Other sediment parameters including the total averages were 5.9% (total organic matter (TOM)), 7.5 (pH), 25.8% (CaCO3), and 88...
  9. Zhou C, Chen Z, Lu X, Wu H, Yang Q, Xu D. Icaritin activates JNK-dependent mPTP necrosis pathway in colorectal cancer cells. Tumour Biol. 2016;37:3135-44 pubmed publisher
    ..Collectively, our results showed that ICT exerts potent inhibitory effect against CRC cells in vitro and in vivo. JNK-dependent mPTP necrosis pathway could be key mechanism responsible for ICT's actions. ..
  10. Loo L, Tiirikainen M, Cheng I, Lum Jones A, Seifried A, Church J, et al. Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer. Genes Chromosomes Cancer. 2013;52:450-66 pubmed publisher
    ..gt;70% of the tumor samples at 20q11-20q13 contained several cancer-related genes (AHCY, POFUT1, RPN2, TH1L, and PRPF6) that were upregulated and demonstrated a significant linear correlation (P < 0...
  11. Petersen L, Klimowicz A, Otsuka S, Elegbede A, Petrillo S, Williamson T, et al. Loss of tumour-specific ATM protein expression is an independent prognostic factor in early resected NSCLC. Oncotarget. 2017;8:38326-38336 pubmed publisher
    ..microarrays, containing 165 formalin-fixed, paraffin-embedded resected NSCLC tumours from patients diagnosed at the Tom Baker Cancer Centre, Calgary, Canada, between 2003 and 2006, were analyzed for ATM expression using quantitative ..
  12. Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed publisher
    ..In addition, mitophagy was demonstrated by an increase in LC3 and TOM-20 colocalization...
  13. Michaud M, Gros V, Tardif M, Brugière S, Ferro M, Prinz W, et al. AtMic60 Is Involved in Plant Mitochondria Lipid Trafficking and Is Part of a Large Complex. Curr Biol. 2016;26:627-39 pubmed publisher
    ..contains proteins located in the two mitochondrial membranes and conserved in all eukaryotic cells, such as the TOM complex and AtMic60, a component of the MICOS complex...
  14. Kutzler M. Intratesticular and intraepididymal injections to sterilize male cats: From calcium chloride to zinc gluconate and beyond. J Feline Med Surg. 2015;17:772-6 pubmed publisher
    ..of intratesticular and intraepididymal injections is to provide an inexpensive non-surgical method for sterilizing tom cats...
  15. Fam H, Choi K, Fougner L, Lim C, Boerkoel C. Reactive oxygen species stress increases accumulation of tyrosyl-DNA phsosphodiesterase 1 within mitochondria. Sci Rep. 2018;8:4304 pubmed publisher
    ..kinases P38 and ERK1, and the translocation of Tdp1 from the nucleus to the mitochondria via the TIM/TOM complex. This translocation occurred independently of mtDNA...
  16. Vutthasathien P, Wattanapermpool J. Regular exercise improves cardiac contractile activation by modulating MHC isoforms and SERCA activity in orchidectomized rats. J Appl Physiol (1985). 2015;119:831-9 pubmed publisher
    Data from the trial known as Testosterone in Older Men with Mobility Limitations (TOM) has indicated an association between testosterone administration and a greater risk for adverse cardiovascular events...
  17. Vermette C, Schwean Lardner K, Gomis S, Grahn B, Crowe T, Classen H. The impact of graded levels of day length on turkey health and behavior to 18 weeks of age. Poult Sci. 2016;95:1223-37 pubmed publisher
    ..trials were completed with each, providing 2 rooms per lighting trt and each room having 3 hen (n = 720) and 3 tom (n = 480) pens...
  18. Basatnia N, Hossein S, Rodrigo Comino J, Khaledian Y, Brevik E, Aitkenhead Peterson J, et al. Assessment of temporal and spatial water quality in international Gomishan Lagoon, Iran, using multivariate analysis. Environ Monit Assess. 2018;190:314 pubmed publisher
    ..least squares regression (OLS) were used in this study to estimate total organic matter content in sediments (TOM) using other parameters such as temperature, dissolved oxygen (DO), pH, electrical conductivity (EC), nitrite (NO<..
  19. Selvanathan S, Graham G, Erkizan H, Dirksen U, Natarajan T, Dakic A, et al. Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. Proc Natl Acad Sci U S A. 2015;112:E1307-16 pubmed publisher
    ..EWS-FLI1 also alters splicing by directly binding to known splicing factors including DDX5, hnRNP K, and PRPF6. Reduction of EWS-FLI1 produces an isoform of γ-TERT that has increased telomerase activity compared with wild-..
  20. Ren Z, Wang X. SlTIR1 is involved in crosstalk of phytohormones, regulates auxin-induced root growth and stimulates stenospermocarpic fruit formation in tomato. Plant Sci. 2016;253:13-20 pubmed publisher
    ..An auxin receptor homolog Solanum lycopersicum TIR1 (SlTIR1) has been isolated from tomato cultivar Micro-Tom, and SlTIR1 over-expression results in parthenocarpic fruit formation...
  21. Milani G, Lana T, Bresolin S, Aveic S, Pastò A, Frasson C, et al. Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways. Mol Cancer Res. 2017;15:683-695 pubmed publisher
    ..Several leukemic cells (K562, LAMA-87, TOM-1, REH, and SHI-1), each carrying a specific chromosomal translocation, were analyzed...
  22. Kułakowska D, Biernacka K, Wilkos E, Rybakowski F, Kucharska Pietura K. [Neurocognitive and social cognition deficits in patients with anorexia nervosa]. Psychiatr Pol. 2014;48:465-75 pubmed
    ..cognition, including mental processes of perception and expression of emotions, disorders of the theory of mind (ToM) and empathy...
  23. Pan C, Ye L, Zheng Y, Wang Y, Yang D, Liu X, et al. Identification and expression profiling of microRNAs involved in the stigma exsertion under high-temperature stress in tomato. BMC Genomics. 2017;18:843 pubmed publisher
    ..Sixteen sRNA libraries of Micro-Tom were constructed from plants stamen and pistil samples and sequenced after 2 d and 12 d of exposure to heat stress, ..
  24. Vermette C, Schwean Lardner K, Gomis S, Crowe T, Classen H. The impact of graded levels of daylength on turkey productivity to eighteen weeks of age. Poult Sci. 2016;95:985-96 pubmed publisher
    ..and 480 toms) were randomly allocated to 8 rooms (2 rooms per lighting trt) with six pens (3 hen--30 per pen and 3 tom--20 per pen) per room in each trial...
  25. Gratão P, Monteiro C, Tezotto T, Carvalho R, Alves L, Peters L, et al. Cadmium stress antioxidant responses and root-to-shoot communication in grafted tomato plants. Biometals. 2015;28:803-16 pubmed publisher
    ..CAT), glutathione reductase (GR), ascorbate peroxidase (APX) and guaiacol peroxidase (GPOX) were analyzed in Micro-Tom grafted plants submitted to cadmium (Cd)...
  26. Shkarupa V, Klymenko S, Таlko V. Cytogenetic analysis of radioprotective properties of sodium lignogumate after gamma-exposure in Allium-test. Probl Radiac Med Radiobiol. 2014;19:490-508 pubmed
    ..Pri e'tom lignogumat natriya proyavlyaet svojstva terapevticheskogo radioprotektora...
  27. Eliasson L, de Freitas H, Dearden L, Calimlim B, Lloyd A. Patients' Preferences for the Treatment of Metastatic Castrate-resistant Prostate Cancer: A Discrete Choice Experiment. Clin Ther. 2017;39:723-737 pubmed publisher
    ..conditional logit model, with odds ratios (ORs) used to indicate preference for attributes, and tradeoff measures (TOM) were estimated using the ratio of coefficients...
  28. Xavier J, Magnat J, Sherman A, Gauthier S, Cohen D, Chaby L. A developmental and clinical perspective of rhythmic interpersonal coordination: From mimicry toward the interconnection of minds. J Physiol Paris. 2016;110:420-426 pubmed publisher
    ..interactions serves as a precursor to higher- level social and cognitive abilities, such as theory of mind (TOM) and empathy...
  29. Martin A, Huang J, Hunold A, Meinzer M. Sex Mediates the Effects of High-Definition Transcranial Direct Current Stimulation on "Mind-Reading". Neuroscience. 2017;366:84-94 pubmed publisher
    Sex differences in social cognitive ability are well established, including measures of Theory of Mind (ToM)...
  30. Koelkebeck K, Liedtke C, Kohl W, Alferink J, Kret M. Attachment style moderates theory of mind abilities in depression. J Affect Disord. 2017;213:156-160 pubmed publisher
    ..Deficits in theory of mind (ToM) functioning hamper this ability and have been observed in depression and other neuropsychiatric disorders...
  31. Quidé Y, Ong X, Mohnke S, Schnell K, Walter H, Carr V, et al. Childhood trauma-related alterations in brain function during a Theory-of-Mind task in schizophrenia. Schizophr Res. 2017;189:162-168 pubmed publisher
    ..Alterations in Theory-of-Mind (ToM), or mentalizing skills, are a hallmark feature of schizophrenia, and are also evident in individuals exposed to ..
  32. Hasni A, Adamson L, Williamson R, Robins D. Adding sound to theory of mind: Comparing children's development of mental-state understanding in the auditory and visual realms. J Exp Child Psychol. 2017;164:239-249 pubmed publisher
    Theory of mind (ToM) gradually develops during the preschool years. Measures of ToM usually target visual experience, but auditory experiences also provide valuable social information...
  33. Pino M, Mazza M, Mariano M, Peretti S, Dimitriou D, Masedu F, et al. Simple Mindreading Abilities Predict Complex Theory of Mind: Developmental Delay in Autism Spectrum Disorders. J Autism Dev Disord. 2017;47:2743-2756 pubmed publisher
    Theory of mind (ToM) is impaired in individuals with autism spectrum disorders (ASD)...
  34. Ferguson H, Cane J. Tracking the impact of depression in a perspective-taking task. Sci Rep. 2017;7:14821 pubmed publisher
    Research has identified impairments in Theory of Mind (ToM) abilities in depressed patients, particularly in relation to tasks involving empathetic responses and belief reasoning...
  35. Bertram K, Agafonov D, Dybkov O, Haselbach D, Leelaram M, Will C, et al. Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell. 2017;170:701-713.e11 pubmed publisher
    ..Our results indicate significant differences between the early activation phase of human and yeast spliceosomes. ..
  36. Makarov E, Makarova O, Achsel T, Luhrmann R. The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. J Mol Biol. 2000;298:567-75 pubmed
    ..Consistent with this idea, we show that in vitro translated U5-102kD protein binds to purified 13S U4/U6 snRNPs, which contain, in addition to the Sm proteins, all known U4/U6-specific proteins. ..
  37. Rigby J, Conroy S, Miele Norton M, Pawlby S, Happé F. Theory of mind as a predictor of maternal sensitivity in women with severe mental illness. Psychol Med. 2016;46:1853-63 pubmed publisher
    ..Schizophrenia is also associated with impairments in attribution of mental states, 'theory of mind' (ToM)...
  38. Bhasin S, Travison T, O BRIEN L, MacKrell J, Krishnan V, Ouyang H, et al. Contributors to the substantial variation in on-treatment testosterone levels in men receiving transdermal testosterone gels in randomized trials. Andrology. 2017;: pubmed publisher
    ..explain the variation in on-treatment testosterone concentrations in men who were randomized to testosterone arm in TOM Trial...
  39. Kim E, Kyeong S, Cheon K, Park B, Oh M, Chun J, et al. Neural responses to affective and cognitive theory of mind in children and adolescents with autism spectrum disorder. Neurosci Lett. 2016;621:117-125 pubmed publisher
    Children and adolescents with Autism Spectrum Disorder (ASD) are characterized by an impaired Theory of Mind (ToM)...
  40. Arumugam K, Renganathan S, Babalola O, Muthunarayanan V. Investigation on paper cup waste degradation by bacterial consortium and Eudrillus eugeinea through vermicomposting. Waste Manag. 2018;74:185-193 pubmed publisher
    ..The results showed that the values of TOC (26.52 and 37.47%), TOM (36.01 and 33.13%) and C/N (15.02 and 11.92%) ratio are reduced in both VC and VCB whereas, the values of pH (8...
  41. Payne J, Porter M, Pride N, North K. Theory of mind in children with Neurofibromatosis Type 1. Neuropsychology. 2016;30:439-48 pubmed publisher
    ..This study examined theory of mind (ToM) in children with NF1 and unaffected controls...
  42. Dunne P, Roberts D, Quinones M, Velligan D, Paredes M, Walss Bass C. Immune markers of social cognitive bias in schizophrenia. Psychiatry Res. 2017;251:319-324 pubmed publisher
    ..measures of social cognitive threat-detection bias (self-referential gaze detection bias and theory of mind (ToM) bias) in delusional versus non-delusional patients...
  43. Adler A, McCleland M, Yee S, Yaylaoglu M, Hussain S, Cosino E, et al. An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. Genes Dev. 2014;28:1068-84 pubmed publisher
    ..Here we report for the first time that PRPF6, a member of the tri-snRNP (small ribonucleoprotein) spliceosome complex, drives cancer proliferation by ..
  44. Béland S, Lepage M. The relative contributions of social cognition and self-reflectiveness to clinical insight in enduring schizophrenia. Psychiatry Res. 2017;258:116-123 pubmed publisher
    ..Research suggests that higher-order social cognitive abilities such as theory of mind (TOM) and metacognition contribute to levels of clinical insight...
  45. Chalah M, Kauv P, Lefaucheur J, Hodel J, Creange A, Ayache S. Theory of mind in multiple sclerosis: A neuropsychological and MRI study. Neurosci Lett. 2017;658:108-113 pubmed publisher
    ..Theory of mind (ToM) is a social cognitive facet that implies the one's ability to predict others' mental states...
  46. Bora E, Kose S. Meta-analysis of theory of mind in anorexia nervosa and bulimia nervosa: A specific İmpairment of cognitive perspective taking in anorexia nervosa?. Int J Eat Disord. 2016;49:739-40 pubmed publisher
    Deficits in theory of mind (ToM), ability to infer mental states of others, can play a significant role in interpersonal difficulties and/or unawareness of illness observed in AN and other eating disorders including bulimia Nervosa (BN)...
  47. Doenyas C, Yavuz H, Selcuk B. Not just a sum of its parts: How tasks of the theory of mind scale relate to executive function across time. J Exp Child Psychol. 2018;166:485-501 pubmed publisher
    There is a well-established relationship between theory of mind (ToM) and executive function (EF) during the preschool years...
  48. Yuryev A, Ono M, Goff S, Macaluso F, Wennogle L. Isoform-specific localization of A-RAF in mitochondria. Mol Cell Biol. 2000;20:4870-8 pubmed
    ..This information is discussed in view of the important role of mitochondria in cellular functions involving energy balance, proliferation, and apoptosis and the potential role of A-RAF in regulating these systems. ..
  49. Liu S, Rauhut R, Vornlocher H, Luhrmann R. The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. RNA. 2006;12:1418-30 pubmed
    ..Both the U5-specific, TPR/HAT-repeat-containing hPrp6 protein and the tri-snRNP-specific hSnu66 protein interact with several U5- and U4/U6-associated proteins, ..
  50. Bora E, Ozerdem A. Social cognition in first-degree relatives of patients with bipolar disorder: A meta-analysis. Eur Neuropsychopharmacol. 2017;27:293-300 pubmed publisher
    ..A novel meta-analysis of theory of mind (ToM) and facial emotion recognition in BP-Rel including 16 studies (728 first-degree relatives of patients with BP and ..
  51. Peterson C, Slaughter V, Wellman H. Nimble negotiators: How theory of mind (ToM) interconnects with persuasion skills in children with and without ToM delay. Dev Psychol. 2018;54:494-509 pubmed publisher
    ..In 2 studies, a total of 167 children aged 3 to 12 years took theory of mind (ToM) tests and participated in unscripted, seminaturalistic persuasive conversations...
  52. Schneider M, Hsiao H, Will C, Giet R, Urlaub H, Luhrmann R. Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nat Struct Mol Biol. 2010;17:216-21 pubmed publisher
    ..previously unidentified phosphoproteins in the human spliceosomal B complex, namely the pre-mRNA processing factors PRP6 and PRP31, both components of the U4/U6-U5 tri-small nuclear ribonucleoprotein (snRNP)...
  53. Davidson D, Vanegas S, Hilvert E. Proneness to Self-Conscious Emotions in Adults With and Without Autism Traits. J Autism Dev Disord. 2017;47:3392-3404 pubmed publisher
    ..Relations between proneness to self-conscious emotions and theory of mind (ToM), fear of negative evaluation, and social functioning were also assessed...
  54. Koo J, Cho J, Lee U. Treadmill exercise alleviates motor deficits and improves mitochondrial import machinery in an MPTP-induced mouse model of Parkinson's disease. Exp Gerontol. 2017;89:20-29 pubmed publisher
    ..Most importantly, treadmill exercise increased expression of the mitochondrial import machinery proteins TOM-40, TOM-20, and TIM-23...
  55. Fan S, Goto K, Chen G, Morinaga H, Nomura M, Okabe T, et al. Identification of the functional domains of ANT-1, a novel coactivator of the androgen receptor. Biochem Biophys Res Commun. 2006;341:192-201 pubmed
    ..The existence of these functional domains may further support the idea that ANT-1 can function as an AR-AF-1-specific coactivator while mediating a transcription-splicing coupling. ..
  56. Burnel M, Perrone Bertolotti M, Reboul A, Baciu M, Durrleman S. Reducing the language content in ToM tests: A developmental scale. Dev Psychol. 2018;54:293-307 pubmed publisher
    ..study was to statistically evaluate the reliable scalability of a set of tasks designed to assess Theory of Mind (ToM) without language as a confounding variable...
  57. Lavoie M, Vistoli D, Sutliff S, Jackson P, Achim A. Social representations and contextual adjustments as two distinct components of the Theory of Mind brain network: Evidence from the REMICS task. Cortex. 2016;81:176-91 pubmed publisher
    Theory of mind (ToM) refers to the ability to infer the mental states of others...
  58. Klindt D, Devaine M, Daunizeau J. Does the way we read others' mind change over the lifespan? Insights from a massive web poll of cognitive skills from childhood to late adulthood. Cortex. 2017;86:205-215 pubmed publisher
    Mentalizing or Theory of Mind (ToM), i.e., the ability to recognize what people think or feel, is a crucial component of human social intelligence...
  59. Munson E. Biographical Feature: Richard B. (Tom) Thomson, Jr., Ph.D., D(ABMM), F(AAM). J Clin Microbiol. 2017;: pubmed publisher
  60. Ruffman T, Puri A, Galloway O, Su J, Taumoepeau M. Variety in parental use of "want" relates to subsequent growth in children's theory of mind. Dev Psychol. 2018;54:677-688 pubmed publisher
    ..Study 2 examined 50 preschoolers, measuring theory of mind (ToM) with tasks and mental state terms, then had parents intervene by reading booklets in which want was used in 1 or ..
  61. Tanackovic G, Ransijn A, Ayuso C, Harper S, Berson E, Rivolta C. A missense mutation in PRPF6 causes impairment of pre-mRNA splicing and autosomal-dominant retinitis pigmentosa. Am J Hum Genet. 2011;88:643-9 pubmed publisher
    ..We screened for mutations in PRPF6 (NM_012469.3), a gene on chromosome 20q13...
  62. van Dooren G, Yeoh L, Striepen B, McFadden G. The Import of Proteins into the Mitochondrion of Toxoplasma gondii. J Biol Chem. 2016;291:19335-50 pubmed publisher
    ..gondii homologue of Tom22 (TgTom22), a central component of the translocon of the outer mitochondrial membrane (TOM) complex, is essential for parasite survival, mitochondrial protein import, and assembly of the TOM complex...
  63. Bora E. Relationship between insight and theory of mind in schizophrenia: A meta-analysis. Schizophr Res. 2017;190:11-17 pubmed publisher
    ..However, social cognitive abilities, particularly, theory of mind (ToM), might also play a role in poor insight in schizophrenia...
  64. Wang Y, Wang Y, Zou Y, Ni K, Tian X, Sun H, et al. Theory of mind impairment and its clinical correlates in patients with schizophrenia, major depressive disorder and bipolar disorder. Schizophr Res. 2017;: pubmed publisher
    Although Theory of Mind (ToM) impairment has been observed in patients with a wide range of mental disorders, the similarity and uniqueness of these deficits across diagnostic groups has not been thoroughly investigated.
  65. Koch V. Delegating Informed Consent. Hastings Cent Rep. 2017;47:5-6 pubmed publisher
    ..Subsequently, she spoke with Tom's physician assistant once by phone and once in person, when she signed the consent form, which did not appear to ..
  66. Wang G, Feng L, Qi J, Li X. Influence of human activities and organic matters on occurrence of polybrominated diphenyl ethers in marine sediment core: A case study in the Southern Yellow Sea, China. Chemosphere. 2017;189:104-114 pubmed publisher
    ..Furthermore, multiple biomarker-based proxies of terrestrial organic matter (TOM) and marine organic matter (MOM) were introduced to systematically investigate the different effects of TOM and MOM ..
  67. Maurage P, D Hondt F, de Timary P, Mary C, Franck N, Peyroux E. Dissociating Affective and Cognitive Theory of Mind in Recently Detoxified Alcohol-Dependent Individuals. Alcohol Clin Exp Res. 2016;40:1926-34 pubmed publisher
    ..Particularly, Theory of Mind (ToM) abilities, which are critical social skills enabling one to understand others' perspectives, and which have been ..
  68. Melin J, Kilisch M, Neumann P, Lytovchenko O, Gomkale R, Schendzielorz A, et al. A presequence-binding groove in Tom70 supports import of Mdl1 into mitochondria. Biochim Biophys Acta. 2015;1853:1850-9 pubmed publisher
    The translocase of the outer mitochondrial membrane (TOM complex) is the general entry gate into mitochondria for almost all imported proteins...
  69. Francesconi M, Minichino A, Carrión R, Chiaie R, Bevilacqua A, Parisi M, et al. Theory of Mind as a mediator variable between neurocognition and functioning in young individuals in treatment with secondary services for non-psychotic disorders. Psychiatry Res. 2016;246:415-420 pubmed publisher
    A large body of studies provides evidence for a link between neurocognition, theory of mind (ToM) and functioning in psychotic spectrum disorders (PSDs), with ToM mediating the effect that neurocognition has on functioning...
  70. Parola A, Berardinelli L, Bosco F. Cognitive abilities and theory of mind in explaining communicative-pragmatic disorders in patients with schizophrenia. Psychiatry Res. 2018;260:144-151 pubmed publisher
    ..their communicative-pragmatic performance; they also have difficulties in cognitive functioning and Theory of Mind (ToM)...
  71. Su L, Chen D, Zhang J, Li X, Pan G, Bai X, et al. The expression and bioinformatic analysis of a novel gene C20orf14 associated with lymphoma. J Huazhong Univ Sci Technolog Med Sci. 2008;28:97-101 pubmed publisher
    ..and reactive lymph node hyperplasia (RLNH), and to perform an initial bioinformatics analysis on a novel gene, C20orf14, which is highly expressed in lymph node of lymphoma...
  72. Weimer A, Parault Dowds S, Fabricius W, Schwanenflugel P, Suh G. Development of constructivist theory of mind from middle childhood to early adulthood and its relation to social cognition and behavior. J Exp Child Psychol. 2017;154:28-45 pubmed publisher
    Two studies examined the development of constructivist theory of mind (ToM) during late childhood and early adolescence...
  73. Chen K, Lee S, Chiang H, Syu Y, Yu X, Hsieh C. Psychometric properties of three measures assessing advanced theory of mind: Evidence from people with schizophrenia. Psychiatry Res. 2017;257:490-496 pubmed publisher
    Patients with schizophrenia tend to have deficits in advanced Theory of Mind (ToM). The "Reading the mind in the eyes" test (RMET), the Faux Pas Task, and the Strange Stories are commonly used for assessing advanced ToM...
  74. Berenguer C, Miranda A, Colomer C, Baixauli I, Roselló B. Contribution of Theory of Mind, Executive Functioning, and Pragmatics to Socialization Behaviors of Children with High-Functioning Autism. J Autism Dev Disord. 2018;48:430-441 pubmed publisher
    ..This study had two objectives: to compare the profile of ToM skills, executive functioning (EF), and pragmatic competence (PC) of children with high-functioning autism (HFA) ..
  75. Zhang T, Cui H, Wei Y, Tang Y, Xu L, Tang X, et al. Progressive decline of cognition during the conversion from prodrome to psychosis with a characteristic pattern of the theory of mind compensated by neurocognition. Schizophr Res. 2018;195:554-559 pubmed publisher
    The association between neurocognition and the theory of mind (ToM) abilities during the progression of psychosis is unclear...
  76. Connan O, Hebert D, Solier L, Maro D, Pellerin G, Voiseux C, et al. Atmospheric tritium concentrations under influence of AREVA NC La Hague reprocessing plant (France) and background levels. J Environ Radioact. 2017;177:184-193 pubmed publisher
    ..m-3 for hourly samples taken in the plume. No tritiated organic molecules (TOM) were detected...
  77. Bowman L, Thorpe S, Cannon E, Fox N. Action mechanisms for social cognition: behavioral and neural correlates of developing Theory of Mind. Dev Sci. 2017;20: pubmed publisher
    ..e. Theory of Mind; ToM)...
  78. Berenguer Forner C, Roselló Miranda B, Baixauli Fortea I, García Castellar R, Colomer Diago C, Miranda Casas A. ADHD Symptoms and peer problems: Mediation of executive function and theory of mind. Psicothema. 2017;29:514-519 pubmed publisher
    ..mechanisms that operate between ADHD symptoms and social problems with peers, considering the mediation of FE and ToM. 35 children with ADHD and 37 with typical development matched in age and IQ were compared...
  79. Croca M, Lagodka A, Gadel R, Bourdel M, Bendjemaa N, Gaillard R, et al. Theory of mind and schizophrenia in young and middle-aged patients: Influence of executive functions. Psychiatry Res. 2018;259:532-537 pubmed publisher
    Theory of Mind (ToM) is compromised in schizophrenia, and responsible for social disability...
  80. Moazam F. Reading Caplan in Karachi. Indian J Med Ethics. 2018;3:66-67 pubmed publisher
    ..how to balance the four, easily memorised philosophical principles popularised by influential American philosophers Tom Beauchamp and Jim Childress...
  81. Meunier H. Do monkeys have a theory of mind? How to answer the question?. Neurosci Biobehav Rev. 2017;82:110-123 pubmed publisher
    ..attention and intention reading, and perspective-taking, ii) alternative hypotheses regarding the underlying mechanisms of such complex behaviors, and iii) potential new perspectives and future directions for studying ToM in monkeys.
  82. Sato S, Idogawa M, Honda K, Fujii G, Kawashima H, Takekuma K, et al. Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing. Gastroenterology. 2005;129:1225-36 pubmed
    ..Certain mRNA splicing abbreviations seen in human cancers may be induced by the activation of the Wnt signaling pathway. ..
  83. Gillespie S, Mitchell I, Abu Akel A. Autistic traits and positive psychotic experiences modulate the association of psychopathic tendencies with theory of mind in opposite directions. Sci Rep. 2017;7:6485 pubmed publisher
    ..psychopathy, and autism and schizophrenia spectrum disorders, have been linked with impairments in Theory of Mind (ToM)...
  84. Goto K, Zhao Y, Saito M, Tomura A, Morinaga H, Nomura M, et al. Activation function-1 domain of androgen receptor contributes to the interaction between two distinct subnuclear compartments. J Steroid Biochem Mol Biol. 2003;85:201-8 pubmed
  85. Nishikimi A, Mukai J, Kioka N, Yamada M. A novel mammalian nuclear protein similar to Schizosaccharomyces pombe Prp1p/Zer1p and Saccharomyces cerevisiae Prp6p pre-mRNA splicing factors. Biochim Biophys Acta. 1999;1435:147-52 pubmed
    ..Indirect immunofluorescent staining showed that the 100-kDa protein localized in the nucleus in HeLa cells. ..
  86. Wampers M, Schrauwen S, De Hert M, Gielen L, Schaeken W. Patients with psychosis struggle with scalar implicatures. Schizophr Res. 2018;195:97-102 pubmed publisher
    ..the second study we additionally explored the possible link between the capacity to derive SIs and theory of mind (ToM) ability. In general, people with psychosis were less likely to derive SIs than controls...
  87. Enrici I, Mitkova A, Castelli L, Lanotte M, Lopiano L, Adenzato M. Deep Brain Stimulation of the subthalamic nucleus does not negatively affect social cognitive abilities of patients with Parkinson's disease. Sci Rep. 2017;7:9413 pubmed publisher
    ..these abilities by simultaneously examining emotion recognition, and both affective and cognitive Theory of Mind (ToM)...
  88. Shikata M, Hoshikawa K, Ariizumi T, Fukuda N, Yamazaki Y, Ezura H. TOMATOMA Update: Phenotypic and Metabolite Information in the Micro-Tom Mutant Resource. Plant Cell Physiol. 2016;57:e11 pubmed publisher
    ..generated by ethylmethane sulfonate (EMS) treatment or γ-ray irradiation in the genetic background of Micro-Tom, a small and rapidly growing variety...
  89. Lecce S, Bianco F, Devine R, Hughes C. Relations between theory of mind and executive function in middle childhood: A short-term longitudinal study. J Exp Child Psychol. 2017;163:69-86 pubmed publisher
    ..with preschool children have shown significant links between children's executive function (EF) and theory of mind (ToM), but few studies have examined these associations in primary school children...