protein disulfide isomerase

Summary

Gene Symbol: protein disulfide isomerase
Description: prolyl 4-hydroxylase subunit beta
Alias: CLCRP1, DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, protein disulfide-isomerase, cellular thyroid hormone-binding protein, collagen prolyl 4-hydroxylase beta, glutathione-insulin transhydrogenase, p55, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide, prolyl 4-hydroxylase, beta polypeptide, protein disulfide isomerase family A, member 1, protein disulfide isomerase-associated 1, protein disulfide isomerase/oxidoreductase, protocollagen hydroxylase, testicular secretory protein Li 32, thyroid hormone-binding protein p55
Species: human
Products:     protein disulfide isomerase

Top Publications

  1. Gallina A, Hanley T, Mandel R, Trahey M, Broder C, Viglianti G, et al. Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry. J Biol Chem. 2002;277:50579-88 pubmed
    We previously reported that monoclonal antibodies to protein-disulfide isomerase (PDI) and other membrane-impermeant PDI inhibitors prevented HIV-1 infection...
  2. Wilkinson B, Gilbert H. Protein disulfide isomerase. Biochim Biophys Acta. 2004;1699:35-44 pubmed
    ..This review focuses specifically on one of these folding assistants, protein disulfide isomerase (PDI), an enzyme that catalyzes disulfide formation and isomerization and a chaperone that inhibits ..
  3. Appenzeller Herzog C, Riemer J, Zito E, Chin K, Ron D, Spiess M, et al. Disulphide production by Ero1?-PDI relay is rapid and effectively regulated. EMBO J. 2010;29:3318-29 pubmed publisher
    ..Both the oxidase Ero1? and the oxidoreductase protein disulphide isomerase (PDI) strongly contribute to the rapid recovery kinetics, but experiments in ERO1-deficient cells indicate the existence ..
  4. Fenouillet E, Barbouche R, Courageot J, Miquelis R. The catalytic activity of protein disulfide isomerase is involved in human immunodeficiency virus envelope-mediated membrane fusion after CD4 cell binding. J Infect Dis. 2001;183:744-52 pubmed
    b>Protein disulfide isomerase (PDI) is a multifunctional protein with thiol-disulfide redox-isomerase activities...
  5. Bi S, Hong P, Lee B, Baum L. Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry. Proc Natl Acad Sci U S A. 2011;108:10650-5 pubmed publisher
    ..On Th2 cells, galectin-9 binds cell surface protein disulfide isomerase (PDI), increasing retention of PDI on the cell surface and altering the redox status at the plasma ..
  6. Barbouche R, Miquelis R, Jones I, Fenouillet E. Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion. J Biol Chem. 2003;278:3131-6 pubmed
    ..Inhibition of lymphocyte surface-associated protein-disulfide isomerase (PDI) blocks HIV/cell fusion, suggesting that redox changes within Env are required...
  7. Meunier L, Usherwood Y, Chung K, Hendershot L. A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol Biol Cell. 2002;13:4456-69 pubmed
    ..ER)-localized multiprotein complex that is comprised of the molecular chaperones BiP; GRP94; CaBP1; protein disulfide isomerase (PDI); ERdj3, a recently identified ER Hsp40 cochaperone; cyclophilin B; ERp72; GRP170; UDP-..
  8. Markovic I, Stantchev T, Fields K, Tiffany L, Tomic M, Weiss C, et al. Thiol/disulfide exchange is a prerequisite for CXCR4-tropic HIV-1 envelope-mediated T-cell fusion during viral entry. Blood. 2004;103:1586-94 pubmed
    ..Catalysts with redox-isomerase activity, such as protein disulfide isomerase (PDI), facilitate Env conversion from its inactive to its fusion-competent conformation...
  9. Wang Z, Zhou Z, Guo Z, Chi C. Snapshot of the interaction between HIV envelope glycoprotein 120 and protein disulfide isomerase. Acta Biochim Biophys Sin (Shanghai). 2010;42:358-62 pubmed
    ..Previous studies suggest the cell surface protein disulfide isomerase (PDI) might interact with disulfide bond(s) of gp120 and thus facilitate HIV-1 entry...

More Information

Publications139 found, 100 shown here

  1. Billington J, Hickling T, Munro G, Halai C, Chung R, Dodson G, et al. Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor binding. J Virol. 2007;81:4604-14 pubmed
    ..Treatment of rgp140 with protein disulfide isomerase (PDI) severely restricted 17b binding capabilities...
  2. Elmasry K, Ibrahim A, Saleh H, Elsherbiny N, Elshafey S, Hussein K, et al. Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy. Diabetologia. 2018;61:1220-1232 pubmed publisher
    ..protein kinase-like ER-regulated kinase (p-PERK), activating transcription factor 6 (ATF6) and protein disulfide isomerase (PDI) in HRECs...
  3. Machado J, Iborra R, Fusco F, Castilho G, Pinto R, Machado Lima A, et al. N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1. Atherosclerosis. 2014;237:343-52 pubmed publisher
    ..were incubated with serum albumin (1 mg/mL; 18 h) from all groups, and the expression of ERS markers (protein disulfide isomerase - PDI, Grp78 and Grp94), ABCA-1 and ABCG-1 determined by immunoblot...
  4. Ye Z, Zhang J, Ancrum T, Manevich Y, Townsend D, Tew K. Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid Redox Signal. 2017;26:247-261 pubmed publisher
    ..involved in the regulation of ER stress (immunoglobulin heavy chain-binding protein [BiP], protein disulfide isomerase [PDI], calnexin, calreticulin, endoplasmin, sarco/endoplasmic reticulum Ca2+-ATPase [SERCA]) ..
  5. Gutierrez T, Simmen T. Endoplasmic reticulum chaperones tweak the mitochondrial calcium rheostat to control metabolism and cell death. Cell Calcium. 2018;70:64-75 pubmed publisher
    ..Although not considered chaperones per se, the ER oxidoreductases of the protein disulfide isomerase (PDI) family complete the folding job by catalyzing the formation of disulfide bonds through cysteine ..
  6. Liu Y, Ji W, Shergalis A, Xu J, Delaney A, Calcaterra A, et al. Activation of the unfolded protein response via inhibition of protein disulfide isomerase decreases the capacity for DNA repair to sensitize glioblastoma to radiotherapy. Cancer Res. 2019;: pubmed publisher
    ..To investigate the therapeutic potential of protein disulfide isomerase (PDI) as a target to overcome resistance to chemoradiation, we developed a GBM tumor model wherein ..
  7. Yuen C, Shek R, Kang B, Matsumoto K, Cho E, Christopher D. Arabidopsis protein disulfide isomerase-8 is a type I endoplasmic reticulum transmembrane protein with thiol-disulfide oxidase activity. BMC Plant Biol. 2016;16:181 pubmed publisher
    ..Terrestrial plants encode six structurally distinct subfamilies of PDIs. The novel PDI-B subfamily is unique to terrestrial plants, and in Arabidopsis is represented by a single member, PDI8...
  8. Chiarelli N, Carini G, Zoppi N, Ritelli M, Colombi M. Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome. PLoS ONE. 2018;13:e0191220 pubmed publisher
    ..Furthermore, the altered distribution of the ER marker protein disulfide isomerase PDI and the strong reduction of the COLLs-modifying enzyme FKBP22 are consistent with the disturbance ..
  9. Moretti A, Pavanelli J, Nolasco P, Leisegang M, Tanaka L, Fernandes C, et al. Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families. Sci Rep. 2017;7:17262 pubmed publisher
    ..The family prototype PDIA1 regulates NADPH oxidase signaling and cytoskeleton organization, however the related underlying mechanisms are ..
  10. Wang H, Shao Y, Zhang W, Li C, Lv Z, Jin C. Molecular characterization of two novel molecular chaperones in bacterial-challenged Apostichopus japonicus. Gene. 2015;570:141-9 pubmed publisher
    Molecular chaperones of 78 kDa glucose-regulated protein (GRP78) and protein disulfide isomerase (PDI) are involved in protein folding and assembly in the endoplasmic reticulum (ER)...
  11. Celebioglu H, Olesen S, Prehn K, Lahtinen S, Brix S, Abou Hachem M, et al. Mucin- and carbohydrate-stimulated adhesion and subproteome changes of the probiotic bacterium Lactobacillus acidophilus NCFM. J Proteomics. 2017;163:102-110 pubmed publisher
    ..Enhanced adhesion ability can prolong bacterial residence in GIT yielding positive health effects. Higher relative abundance of certain surface proteins under various conditions (i...
  12. Vatolin S, Phillips J, Jha B, Govindgari S, Hu J, Grabowski D, et al. Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma. Cancer Res. 2016;76:3340-50 pubmed publisher
    ..Thus, inhibition of protein disulfide isomerases (PDI) required for protein folding in the endoplasmic reticulum (ER) should increase ER stress beyond repair in this ..
  13. Cowling R, Park J, Sotimehin A, Greenberg B. Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion. J Mol Cell Cardiol. 2017;113:1-8 pubmed publisher
    ..There were no differences in the levels of protein disulfide isomerase (P4HB/PDI) or the triple-helical procollagen chaperone, HSP47, with or without ascorbate...
  14. Langsjoen R, Auguste A, Rossi S, Roundy C, Penate H, Kastis M, et al. Host oxidative folding pathways offer novel anti-chikungunya virus drug targets with broad spectrum potential. Antiviral Res. 2017;143:246-251 pubmed publisher
    ..for proper folding and assembly of the E1 and E2 envelope glycoproteins, and likely depend on host protein disulfide isomerase-family enzymes (PDI) to aid in facilitating disulfide bond formation and isomerization in these ..
  15. Liyanage D, Omeka W, Lee J. Molecular characterization, host defense mechanisms, and functional analysis of ERp44 from big-belly seahorse: A novel member of the teleost thioredoxin family present in the endoplasmic reticulum. Comp Biochem Physiol B Biochem Mol Biol. 2019;232:31-41 pubmed publisher
    Endoplasmic reticulum resident protein 44 (ERp44) is a protein disulfide isomerase (PDI) and a member of thioredoxin family, which is involved in several functions such as oxidative folding and polymerization of molecules, carrier ..
  16. Trevelin S, Lopes L. Protein disulfide isomerase and Nox: new partners in redox signaling. Curr Pharm Des. 2015;21:5951-63 pubmed
    ..b>Protein disulfide isomerase (PDI) is a thiol oxidoreductase member of the thioredoxin family that has multiple roles in cellular ..
  17. Benedikter B, Volgers C, van Eijck P, Wouters E, Savelkoul P, Reynaert N, et al. Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants. Free Radic Biol Med. 2017;108:334-344 pubmed publisher
    ..acrolein, 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB), bacitracin, rutin or the anti-protein disulfide isomerase (PDI) antibody clone RL90; with or without NAC or GSH...
  18. Belcastro E, Wu W, Fries Raeth I, Corti A, Pompella A, Leroy P, et al. Oxidative stress enhances and modulates protein S-nitrosation in smooth muscle cells exposed to S-nitrosoglutathione. Nitric Oxide. 2017;69:10-21 pubmed publisher
    ..enzymes involved in GSNO metabolism (activity of gamma-glutamyltransferase, GGT, and expression of protein disulfide isomerase, PDI) were evaluated...
  19. Song J, Finnerty C, Herndon D, Boehning D, Jeschke M. Severe burn-induced endoplasmic reticulum stress and hepatic damage in mice. Mol Med. 2009;15:316-20 pubmed publisher
    ..Significantly, upregulation of the ER stress markers glucose-related protein 78 (GRP78)/BIP, protein disulfide isomerase (PDI), p-protein kinase R-like endoplasmic reticulum kinase (p-PERK), and inositol-requiring enzyme ..
  20. Choi S, Lee E, Jeong J, Akuzum B, Maeng Y, Kim T, et al. 4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2. Biochem Biophys Res Commun. 2016;477:841-846 pubmed publisher
    ..We found that the ER chaperone binding immunoglobulin protein (BiP) and the protein disulfide isomerase (PDI) were elevated in GCD2...
  21. Ko A, Kim J, Hyun H, Kim J. Endoplasmic reticulum (ER) stress protein responses in relation to spatio-temporal dynamics of astroglial responses to status epilepticus in rats. Neuroscience. 2015;307:199-214 pubmed publisher
    ..Glucose-related protein (GRP) 78 and protein disulfide isomerase (PDI) expressions were transiently increased in CA1 neurons and dentate granule cells, and subsequently ..
  22. Chen Y, Wen L, Ho K, Juang R, Lin C. Lemon protein disulfide isomerase: cDNA cloning and biochemical characterization. Bot Stud. 2013;54:34 pubmed publisher
    ..A ClPDI cDNA (1828 bp, GenBank accession HM641784) encoding a putative PDI from Citrus limonum was cloned by polymerase chain reaction (PCR)...
  23. Segura A, Bertoni M, Auffret P, Klopp C, Bouchez O, Genthon C, et al. Transcriptomic analysis reveals specific metabolic pathways of enterohemorrhagic Escherichia coli O157:H7 in bovine digestive contents. BMC Genomics. 2018;19:766 pubmed publisher
    The cattle gastrointestinal tract (GIT) is the main enterohemorrhagic Escherichia coli (EHEC) reservoir...
  24. Di Rocco G, Baldari S, Gentile A, Capogrossi M, Toietta G. Protein disulfide isomerase as a prosurvival factor in cell therapy for muscular and vascular diseases. Stem Cell Res Ther. 2018;9:250 pubmed publisher
    ..b>Protein disulfide isomerase (PDI) is a molecular chaperone induced and activated by ER stress...
  25. JAISWAL A, Khare P, Joshi S, Kushawaha P, Sundar S, Dube A. Th1 stimulatory proteins of Leishmania donovani: comparative cellular and protective responses of rTriose phosphate isomerase, rProtein disulfide isomerase and rElongation factor-2 in combination with rHSP70 against visceral leishmaniasis. PLoS ONE. 2014;9:e108556 pubmed publisher
    ..identified several Th1-stimulatory proteins of Leishmania donovani -triose phosphate isomerase (TPI), protein disulfide isomerase (PDI) and elongation factor-2 (EL-2) etc...
  26. Chien C, Hung Y, Shieh Y, Hsieh C, Lu C, Lin F, et al. A novel potential biomarker for metabolic syndrome in Chinese adults: Circulating protein disulfide isomerase family A, member 4. PLoS ONE. 2017;12:e0179963 pubmed publisher
    b>Protein disulfide isomerase (PDI) family members are specific endoplasmic reticulum proteins that are involved in the pathogenesis of numerous diseases including neurodegenerative diseases, cancer and obesity...
  27. Kitamura A, Ishida Y, Kubota H, Pack C, Homma T, Ito S, et al. Detection of substrate binding of a collagen-specific molecular chaperone HSP47 in solution using fluorescence correlation spectroscopy. Biochem Biophys Res Commun. 2018;497:279-284 pubmed publisher
    ..a green fluorescent dye, decreased upon addition of type I or III collagen, whereas that of dye-labeled protein disulfide isomerase (PDI) or bovine serum albumin (BSA) did not, indicating that specific binding of HSP47 to collagen ..
  28. Hajer J. [Cannabis - therapy for the future?]. Vnitr Lek. 2015;61:680-5 pubmed
    ..Of the different types of CAM patients with GIT diseases tend to prefer in particular homeopathy, acupuncture and not least phytotherapy, where therapeutic use of ..
  29. Azghay M, Bouchaud O, Mechaï F, Nicaise P, Fain O, Stirnemann J. Utility of QuantiFERON-TB Gold In-Tube assay in adult, pulmonary and extrapulmonary, active tuberculosis diagnosis. Int J Infect Dis. 2016;44:25-30 pubmed publisher
    ..The aim of this study was to analyse the contribution of the QuantiFERON-TB Gold In-Tube assay (QFT-GIT) to TB diagnosis...
  30. Zeeshan H, Lee G, Kim H, Chae H. Endoplasmic Reticulum Stress and Associated ROS. Int J Mol Sci. 2016;17:327 pubmed publisher
    ..evidence suggests the interrelation of ER stress and ROS with redox signaling mediators such as protein disulfide isomerase (PDI)-endoplasmic reticulum oxidoreductin (ERO)-1, glutathione (GSH)/glutathione disuphide (GSSG), ..
  31. Hashad R, Ishak R, Geneidi A, Mansour S. Methotrexate loading in chitosan nanoparticles at a novel pH: Response surface modeling, optimization and characterization. Int J Biol Macromol. 2016;91:630-9 pubmed publisher
    ..investigated were the entrapment efficiency (EE%), mean hydrodynamic particle size (PS), polydispersity index (PDI) and zeta potential (ZP)...
  32. Li X, Zhang Y, Wei Z, Guan Z, Cai Y, Liao X. Antifungal Activity of Isolated Bacillus amyloliquefaciens SYBC H47 for the Biocontrol of Peach Gummosis. PLoS ONE. 2016;11:e0162125 pubmed publisher
    ..In a field trial, the decreases in the infected gummosis rate (IGR) and the disease severity index (DSI) through cell suspension treatments were 20% and 57.5% (in 2014), respectively, and 40% and 57...
  33. Filannino P, di Cagno R, Addante R, Pontonio E, Gobbetti M. Metabolism of Fructophilic Lactic Acid Bacteria Isolated from the Apis mellifera L. Bee Gut: Phenolic Acids as External Electron Acceptors. Appl Environ Microbiol. 2016;82:6899-6911 pubmed publisher
    ..Thus, the selection of FLAB strains as starter cultures with specific enzymatic activities involving phenolic acids may have a promising role in food fermentations. ..
  34. Gao H, Chen Z, Fu Y, Yang X, Weng R, Wang R, et al. Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress. Sci Rep. 2016;6:34403 pubmed publisher
    ..from the nucleus to cytosol and Endoplasm reticulum (ER) and induced co-localization of Tom20/Nur77 and Protein Disulfide Isomerase (PDI)/Nur77...
  35. Ismail M, Morsi H, Abdulateef N, Noaman M, Abou El Ella G. Evaluation of prothrombin induced by vitamin K absence, macrophage migration inhibitory factor and Golgi protein-73 versus alpha fetoprotein for hepatocellular carcinoma diagnosis and surveillance. Scand J Clin Lab Invest. 2017;77:175-183 pubmed publisher
    ..MIF may serve as a promising screening tumor marker for the detection of gastrointestinal tract (GIT) malignancy.
  36. Manuel A, Walla M, Faccenda A, Martin S, Tanis R, Piroli G, et al. Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes. Antioxid Redox Signal. 2017;27:1281-1296 pubmed publisher
    ..The endoplasmic reticulum (ER) oxidoreductase protein disulfide isomerase (PDI) is succinated in adipocytes that are matured in high glucose, and in this study we investigated ..
  37. Hussein M, Woo T, Yun I, Park H, Kim Y. Analysis of the correlation between deformational plagiocephaly and neurodevelopmental delay. J Plast Reconstr Aesthet Surg. 2018;71:112-117 pubmed publisher
    ..The means of the mental development index (MDI) and psychomotor development index (PDI) were 91.69 ± 16.8 and 92.28 ± 17...
  38. Parakh S, Atkin J. Protein folding alterations in amyotrophic lateral sclerosis. Brain Res. 2016;1648:633-649 pubmed publisher
    ..Chaperone proteins, including heat shock proteins (Hsp׳s) and the protein disulphide isomerase (PDI) family, assist in protein folding and therefore can prevent protein misfolding, and have been implicated as being ..
  39. Peichoto M, Santoro M. Patagonfibrase modifies protein expression of tissue factor and protein disulfide isomerase in rat skin. Toxicon. 2016;119:330-5 pubmed publisher
    ..Our aim was to determine whether patagonfibrase affects the expression of TF and protein disulfide isomerase (PDI), an enzyme that controls TF biological activity, at the site of patagonfibrase injection, and ..
  40. Flaumenhaft R. Advances in vascular thiol isomerase function. Curr Opin Hematol. 2017;24:439-445 pubmed publisher
    ..The initial observation that protein disulfide isomerase (PDI) functions in thrombus formation occurred approximately a decade ago...
  41. Gandara L, Mamone L, Bohm G, Buzzola F, Casas A. Enhancement of photodynamic inactivation of Staphylococcus aureus biofilms by disruptive strategies. Lasers Med Sci. 2017;32:1757-1767 pubmed publisher
    Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers and visible light. On the one hand, near-infrared treatment (NIRT) has also bactericidal and dispersal effects on biofilms...
  42. Fall M, Boyse J, Wang D, Willbur J, Smith D, Chilvers M. Case Study of an Epidemiological Approach Dissecting Historical Soybean Sclerotinia Stem Rot Observations and Identifying Environmental Predictors of Epidemics and Yield Loss. Phytopathology. 2017;: pubmed publisher
    ..5 mm. A biphasic sigmoidal curve accurately described the relationship between SSR disease severity index (DSI) and yield, with a DSI threshold of 22, below which minimal yield loss was observed...
  43. Wong K, Sun F, Trudel G, Sebastiani P, Laneuville O. Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures. BMC Musculoskelet Disord. 2015;16:125 pubmed publisher
    ..The identification of altered expression of genes and biochemical pathways in the joint capsule provides potential targets for the therapy of knee flexion contractures. ..
  44. Priori D, Colombo M, Clavenzani P, Jansman A, Lallès J, Trevisi P, et al. The Olfactory Receptor OR51E1 Is Present along the Gastrointestinal Tract of Pigs, Co-Localizes with Enteroendocrine Cells and Is Modulated by Intestinal Microbiota. PLoS ONE. 2015;10:e0129501 pubmed publisher
    The relevance of the butyrate-sensing olfactory receptor OR51E1 for gastrointestinal (GIT) functioning has not been considered so far...
  45. Jain S, Reddy V, Arora S, Patel K. Development of surface stabilized candesartan cilexetil nanocrystals with enhanced dissolution rate, permeation rate across CaCo-2, and oral bioavailability. Drug Deliv Transl Res. 2016;6:498-510 pubmed publisher
    ..The particle size, polydispersity index (PDI), and zeta potential of optimized formulation was found to be 159 ± 8.1 nm, 0...
  46. De Bock F, Will H, Behrenbeck U, Jarczok M, Hadders Algra M, Philippi H. Predictive value of General Movement Assessment for preterm infants' development at 2 years - implementation in clinical routine in a non-academic setting. Res Dev Disabil. 2017;62:69-80 pubmed publisher
    ..two years was based upon the Bayley Scales of Infant Development-II (mental/psychomotor developmental index (MDI, PDI)) and a neurological examination...
  47. De Smet J, Croubels S, De Backer P, Devreese M. Effect of administration route and dose alteration on sulfadiazine-trimethoprim plasma and intestinal concentrations in pigs. Int J Antimicrob Agents. 2017;50:707-714 pubmed publisher
    ..of blood and faeces, the intestinal content of all animals was sampled in different gastrointestinal tract (GIT) segments, and SDZ and TRIM were quantified...
  48. Seven Y, Nichols N, Kelly M, Hobson O, Satriotomo I, Mitchell G. Compensatory plasticity in diaphragm and intercostal muscle utilization in a rat model of ALS. Exp Neurol. 2018;299:148-156 pubmed publisher
    ..neuron loss and decreased phrenic nerve activity, diaphragm electrical activity and trans-diaphragmatic pressure (Pdi) are maintained to sustain ventilation...
  49. Madureira A, Campos D, Oliveira A, Sarmento B, Pintado M, Gomes A. Insights into the protective role of solid lipid nanoparticles on rosmarinic acid bioactivity during exposure to simulated gastrointestinal conditions. Colloids Surf B Biointerfaces. 2016;139:277-84 pubmed publisher
    ..witepsol and carnauba SLN loaded with rosmarinic acid (RA) were exposed to the simulated gastrointestinal tract (GIT) conditions prevailing in stomach and small intestine...
  50. Shang P, Lu G, Sun X, Bian Z, Shang Z, Li J. The influence of continuous glucose monitoring of high-risk neonate on guiding perinatal complications and one-year follow-up results. Eur Rev Med Pharmacol Sci. 2016;20:125-8 pubmed
    ..The mental development index (MDI) and the physical development index (PDI) of hypoglycemic group were significantly lower than those in the normal group and differences were statistically ..
  51. Sun M, Yin W, Dong X, Yang W, Zhao Y, Yin M. Fluorescent supramolecular micelles for imaging-guided cancer therapy. Nanoscale. 2016;8:5302-12 pubmed publisher
    A novel smart fluorescent drug delivery system composed of a perylene diimide (PDI) core and block copolymer poly(d,l-lactide)-b-poly(ethyl ethylene phosphate) is developed and named as PDI-star-(PLA-b-PEEP)8...
  52. Dai G, Das A, Hayashi E, Chen Q, Takahashi E. Regional variation of white matter development in the cat brain revealed by ex vivo diffusion MR tractography. Int J Dev Neurosci. 2016;54:32-38 pubmed publisher
    ..We applied diffusion spectrum imaging (DSI) tractography to five juvenile ex vivo cat brains at postnatal day (P) 35, when the degree of myelination varies ..
  53. Pullens B, Hakkesteegt M, Hoeve H, Timmerman M, Joosten K. Voice outcome and voice-related quality of life after surgery for pediatric laryngotracheal stenosis. Laryngoscope. 2017;127:1707-1711 pubmed publisher
    ..The dysphonia severity index (DSI) was used as an objective measurement for voice quality...
  54. Mohanty A, Jena B. Innate catalytic and free radical scavenging activities of silver nanoparticles synthesized using Dillenia indica bark extract. J Colloid Interface Sci. 2017;496:513-521 pubmed publisher
    ..35nm and dynamic light scattering (DLS) studies showed the average particle size of 29nm with polydispersity index (PDI) of 0.280. Synthesized AgNPs were showing surface functionalization as revealed through FTIR studies...
  55. Christiaens M, Collette S, Overgaard J, Gregoire V, Kazmierska J, Castadot P, et al. Quality assurance of radiotherapy in the ongoing EORTC 1219-DAHANCA-29 trial for HPV/p16 negative squamous cell carcinoma of the head and neck: Results of the benchmark case procedure. Radiother Oncol. 2017;123:424-430 pubmed publisher
    ..Sørensen-Dice similarity index (DSI) and the 95th percentile Hausdorff distance (HD) were retrospectively used to evaluate the agreement between the ..
  56. Trovitch R. The Emergence of Manganese-Based Carbonyl Hydrosilylation Catalysts. Acc Chem Res. 2017;50:2842-2852 pubmed publisher
    ..In our initial 2014 communication, we reported that the bis(imino)pyridine-supported compound (Ph2PPrPDI)Mn mediates ketone hydrosilylation with exceptional activity under solvent-free conditions...
  57. Ko H, Uehara T, Nomura Y. Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stress-induced apoptotic cell death. J Biol Chem. 2002;277:35386-92 pubmed
    ..Previously, we found that protein-disulfide isomerase (PDI) is specifically up-regulated in response to hypoxia/brain ischemia in astrocytes...
  58. Wakchaure V, Kaib P, Leutzsch M, List B. Disulfonimide-Catalyzed Asymmetric Reduction of N-Alkyl Imines. Angew Chem Int Ed Engl. 2015;54:11852-6 pubmed publisher
    A chiral disulfonimide (DSI)-catalyzed asymmetric reduction of N-alkyl imines with Hantzsch esters as a hydrogen source in the presence of Boc2 O has been developed...
  59. Yeates A, Love T, Engström K, Mulhern M, McSorley E, Grzesik K, et al. Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study. Prostaglandins Leukot Essent Fatty Acids. 2015;102-103:13-20 pubmed publisher
    ..A trend for improved PDI was found among infants born to mothers with the minor rs3834458 allele...
  60. Kallscheuer N, Vogt M, Kappelmann J, Krumbach K, Noack S, Bott M, et al. Identification of the phd gene cluster responsible for phenylpropanoid utilization in Corynebacterium glutamicum. Appl Microbiol Biotechnol. 2016;100:1871-81 pubmed publisher
    ..glutamicum strains carrying single-gene deletions showed that loss of phdA, phdB, phdC, or phdE abolished growth of C. glutamicum with all phenylpropanoid substrates tested...
  61. Martinussen L, Møller M, Prato C, Haustein S. How indicative is a self-reported driving behaviour profile of police registered traffic law offences?. Accid Anal Prev. 2017;99:1-5 pubmed publisher
    ..of drivers were identified based on the Driver Behaviour Questionnaire (DBQ) and the Driver Skill Inventory (DSI), while traffic offences and accidents were register-based (Statistics Denmark)...
  62. Hanna L, Basalious E, ElGazayerly O. Respirable controlled release polymeric colloid (RCRPC) of bosentan for the management of pulmonary hypertension: in vitro aerosolization, histological examination and in vivo pulmonary absorption. Drug Deliv. 2016;24:188-198 pubmed publisher
    ..The particle size, polydispersity index (PDI), entrapment efficiency (EE) and in vitro bosentan released were selected as dependent variables...
  63. Dufour C, Loonis M, Delosière M, Buffiere C, Hafnaoui N, Sante Lhoutellier V, et al. The matrix of fruit & vegetables modulates the gastrointestinal bioaccessibility of polyphenols and their impact on dietary protein digestibility. Food Chem. 2018;240:314-322 pubmed publisher
    ..numerous positive health effects, ascribed either to their antioxidant activity within the gastrointestinal tract (GIT) or to bioactivity of their absorbed metabolites...
  64. Jo Y, Benoist D, Barbano D, Drake M. Flavor and flavor chemistry differences among milks processed by high-temperature, short-time pasteurization or ultra-pasteurization. J Dairy Sci. 2018;101:3812-3828 pubmed publisher
    ..and shorter refrigerated shelf life compared with ultra-pasteurization (UP) achieved by direct steam injection (DSI-UP) or indirect heat (IND-UP)...
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