Gene Symbol: PLEKHA6
Description: pleckstrin homology domain containing A6
Alias: PEPP-3, PEPP3, pleckstrin homology domain-containing family A member 6, PH domain-containing family A member 6, phosphoinositol 3-phosphate-binding protein 3
Species: human
Products:     PLEKHA6

Top Publications

  1. Dowler S, Currie R, Campbell D, Deak M, Kular G, Downes C, et al. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J. 2000;351:19-31 pubmed
    ..We have also identified two related homologues of PEPP1, termed PEPP2 and PEPP3, that may also interact with PtdIns3P...
  2. Leparc G, Mitra R. Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human. Nucleic Acids Res. 2007;35:3192-202 pubmed
    ..Overall, PASE was able to uncover 59 novel alternative cassette exons in C. elegans and humans through a genome-wide ab initio prediction method that enriches for exons involved in signaling. ..
  3. Spellmann I, Rujescu D, Musil R, Meyerwas S, Giegling I, Genius J, et al. Pleckstrin homology domain containing 6 protein (PLEKHA6) polymorphisms are associated with psychopathology and response to treatment in schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry. 2014;51:190-5 pubmed publisher
    ..By analyzing microarray data, we observed an increase of pleckstrin homology domain containing 6 (PLEKHA6) gene expression...
  4. Clark T, Schweitzer A, Chen T, Staples M, Lu G, Wang H, et al. Discovery of tissue-specific exons using comprehensive human exon microarrays. Genome Biol. 2007;8:R64 pubmed
    ..In addition, we identified and validated a number of novel exons with tissue-specific splicing patterns. The tissue map data will likely serve as a valuable source of information on the regulation of alternative splicing. ..