Research Topics
Genomes and Genes | PHI 1SummaryGene Symbol: PHI 1 Description: protein phosphatase 1, regulatory (inhibitor) subunit 14B Alias: PHI-1, PLCB3N, PNG, SOM172, phospholipase C beta-3 neighboring gene protein, phospholipase C-beta-3 neighbouring gene protein, protein phosphatase 1 regulatory subunit 14B Species: human Top Publications
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Publications
Effect of naltrexone treatment on insulin secretion, insulin action and postprandial thermogenesis in obesityR Vettor
Istituto di Semeiotica Medica, Patologia Medica III, , Italy
Horm Metab Res 26:188-94. 1994..measured blood glucose, plasma insulin and C-peptide concentrations and evaluated the following parameters: first (phi 1) and second (phi 2) phase of beta-cell sensitivity, insulin sensitivity and glucose effectiveness...
Comparison of the insulinotropic activity of glucagon-superfamily peptides in rat pancreas perfusionS Suzuki
Department of Internal Medicine, University of Tsukuba, Japan
Horm Metab Res 24:458-61. 1992....
A curious coincidence: mosquito biodiversity and the limits of the Japanese encephalitis virus in AustralasiaStephane Hemmerter
Institute for the Biotechnology of Infectious Diseases, University of Technology, Sydney, New South Wales, Australia
BMC Evol Biol 7:100. 2007..is also responsible for the establishment of the Japanese encephalitis virus (JEV) in southern Papua New Guinea (PNG) as well as its incursions into northern Australia...
Failure of chloroquine prophylaxis for falciparum malaria in pregnant women in Madang, Papua New GuineaB J Brabin
Institute of Medical Research, Madang, Papua New Guinea
Ann Trop Med Parasitol 84:1-9. 1990..living under conditions of year-round transmission of malaria in a rural coastal area of Madang, Papua New Guinea (PNG), were followed while attending mobile antenatal clinics and receiving chloroquine prophylaxis (300 mg base weekly)...
Nutrition, infection and child growth in Papua New GuineaS J Ulijaszek
Department of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom
Coll Antropol 24:423-9. 2000Growth patterns of populations in Papua New Guinea (PNG) have traditionally shown considerable variation, with the greatest difference lying between coastal and highland populations...
Mortality in a rural area of Madang Province, Papua New GuineaJ S Moir
Papua New Guinea Institute of Medical Research, Madang
Ann Trop Med Parasitol 83:305-19. 1989..programme undertaken by the Papua New Guinea Institute of Medical Research near the town of Madang, northern PNG, a three-year study of mortality was conducted in a rural population of approximately 16,500 people...
A mark-recapture experiment with the filariasis vector Anopheles punctulatus in Papua New GuineaJ D Charlwood
Papua New Guinea Institute of Medical Research, Madang
Ann Trop Med Parasitol 81:429-36. 1987A capture-recapture experiment with the filariasis vector Anopheles punctulatus from Papua New Guinea (PNG) is described...
Mycotoxins and toxigenic fungi in sago starch from Papua New GuineaA R Greenhill
Environmental and Public Health Microbiology Research Group, School of Veterinary and Biomedical Sciences, James Cook University, Townsville, QLD, Australia
Lett Appl Microbiol 47:342-7. 2008To assay sago starch from Papua New Guinea (PNG) for important mycotoxins and to test fungal isolates from sago for mycotoxin production in culture.
High-throughput molecular diagnosis of circumsporozoite variants VK210 and VK247 detects complex Plasmodium vivax infections in malaria endemic populations in Papua New GuineaCara N Henry-Halldin
Center for Global Health and Diseases, Case Western Reserve University, Wolstein Research Building, Room 4 125, 2103 Cornell Rd, Cleveland, OH 44106, USA
Infect Genet Evol 11:391-8. 2011Malaria is endemic in lowland and coastal regions of Papua New Guinea (PNG), and is caused by Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae and Plasmodium ovale. Infection by P...
Village distance from urban centre as the prime modernization variable in differences in blood pressure and body mass index of adults of the Purari delta of the Gulf Province, Papua New GuineaStanley J Ulijaszek
Institute of Social and Cultural Anthropology, University of Oxford, UK
Ann Hum Biol 32:326-38. 2005..geographical proximity of villages to an urban centre and other modernization variables are associated with variation in blood pressure and body mass index (BMI) of adults of the Purari delta of the Gulf Province, Papua New Guinea (PNG).
The ameliorating effects of the cognitive-enhancing Chinese herbs on scopolamine-induced amnesia in ratsM T Hsieh
Institute of Chinese Pharmaceutical Sciences, China Medical College, Taiwan, R O C
Phytother Res 14:375-7. 2000..of the cognitive-enhancing Chinese herbs administered orally for 1 week-Panax ginseng (PG), Panax notoginseng (PNG), Dioscorea opposita (DO), Gastrodia elata (GE), Salvia miltiorrhiza (SM), Acorus gramineus (AG), Coptis chinensis (..
Common themes in the literature on traditional medicine in Papua New GuineaJoan Macfarlane
Centre for International Health, Curtin University of Technology, Perth, Australia
P N G Med J 52:44-53. 2009A review of the literature on traditional medical practices and beliefs in Papua New Guinea (PNG) was conducted in order to provide context and background information for the Department of Health's National Policy on Traditional Medicine ..
Surgical capability and surgical pathology in Papua New Guinea in the year 2000D A Watters
Department of Clinical and Biomedical Sciences, University of Melbourne, Geelong Hospital, Victoria, Australia
ANZ J Surg 71:274-80. 2001Papua New Guinea (PNG) is a country of 4.5 million people with an annual health budget of only 96 million Kina (1K = US$0.35). There are 19 hospitals in the country and national surgeons are now staffing most of these hospitals...
The effect of bacteria on the sensitivity of microalgae to copper in laboratory bioassaysJacqueline L Levy
Centre for Environmental Contaminants Research, CSIRO Land and Water, Private Mailbag 7, Lucas Heights, NSW 2234, Australia
Chemosphere 74:1266-74. 2009..closterium, P. subcapitata or for Chlorella sp. (PNG isolate). At pH 5.7, the axenic Chlorella sp...
Glycophorin C (Gerbich antigen blood group) and band 3 polymorphisms in two malaria holoendemic regions of Papua New GuineaSheral S Patel
Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio 44106, USA
Am J Hematol 75:1-5. 2004..In Papua New Guinea (PNG), the Gerbich-negative phenotype is caused by an exon 3 deletion in the glycophorin C gene (GYPCDeltaex3) while ..
Are insecticide-treated bednets more protective against Plasmodium falciparum than Plasmodium vivax-infected mosquitoes?Moses J Bockarie
Papua New Guinea Institute of Medical Research, PO Box 378, Madang, Papua New Guinea
Malar J 5:15. 2006..falciparum or P. vivax. This paper describes the biting cycle of P. falciparum and P. vivax-infected mosquitoes and the impact of an ITN intervention on the proportion of mosquitoes infected with either parasite species...
The use of isoenzyme electrophoresis in the taxonomy of StrongyloidesM E Viney
Department of Parasitology, Liverpool School of Tropical Medicine
Ann Trop Med Parasitol 84:35-47. 1990..traditional taxonomic methods combined with the discovery of a Strongyloides parasitic in man in Papua New Guinea (PNG) that resembles S...
User charges and utilisation of obstetric services in the National Capital District, Papua New GuineaA L Benjamin
NCD Health Services, National Capital District, Papua New Guinea
Pac Health Dialog 8:38-43. 2001..However, the scope of this study cannot be used to generalise the trend in PNG because the scenerio in the rural areas will vary from urban.
Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1Jutta Marfurt
Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland
J Infect Dis 198:409-17. 2008..However, data on the molecular correlates involved in the development of resistance to 4-aminoquinolines and their association with the in vivo treatment response are scarce...
Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assayCarmen Fernandez-Becerra
Barcelona Centre for International Health Research CRESIB, Hospital Clinic IDIBAPS, Universitat de Barcelona, Rosello 132, 08036 Barcelona, Spain
Malar J 9:29. 2010....
Current status of Taenia solium and cysticercosis in Papua New GuineaIfor L Owen
C o National Agriculture Quarantine and Inspection Authority, Papua New Guinea
Parasitol Int 55:S149-53. 2006There is no evidence that taeniasis due to Taenia solium is present in Papua New Guinea (PNG), but there is some serological evidence that human cysticercosis exists at particular locations near the border with West Papua (Indonesia), ..
Population hemoglobin mean and anemia prevalence in Papua New Guinea: new metrics for defining malaria endemicity?Nicolas Senn
Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea
PLoS ONE 5:e9375. 2010....
In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New GuineaRina P M Wong
Fremantle Unit, School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA, Australia
Trop Med Int Health 15:342-9. 2010Recent clinical studies have shown high rates of malaria treatment failure in endemic areas of Papua New Guinea (PNG), necessitating a change of treatment from chloroquine (CQ) or amodiaquine (AQ) plus sulphadoxine-pyrimethamine to the ..
The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus sulphadoxine-pyrimethamine against falciparum malaria in Papua New GuineaJutta Marfurt
Swiss Tropical Institute, Socinstrasse 57, P, O, Box, CH 4002 Basel, Switzerland
Malar J 7:61. 2008In Papua New Guinea (PNG), combination therapy with amodiaquine (AQ) or chloroquine (CQ) plus sulphadoxine-pyrimethamine (SP) was introduced as first-line treatment against uncomplicated malaria in 2000.
Beyond risk factors to lived experiences: young women's experiences of health in Papua New GuineaRachael L Hinton
Centre for International Health, Curtin University of Technology, Perth, Western Australia, Australia
Rural Remote Health 9:1257. 2009The health of young women in rural Papua New Guinea (PNG) is often examined using individual-based risk factors which are decontextualized from the social and cultural relationships within which women's lives are embedded...
Scrub typhus (Orientia tsutsugamushi), spotted fever (Rickettsia australis) and dengue fever as possible causes of mysterious deaths in the Strickland Gorge area of Southern Highlands and West Sepik Provinces of Papua New GuineaP E Spicer
HMAS Cairns Naval Base, Australia
P N G Med J 50:172-83. 2007..a mysterious haemorrhagic disease and deaths in the remote picturesque Strickland River area of Papua New Guinea (PNG)...
A high incidence of polymorphic CYP2C19 variants in archival blood samples from Papua New GuineaHuai Ling Hsu
Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
Hum Genomics 3:17-23. 2008..The colonisation of the Pacific Islands is believed to have involved migration through Papua New Guinea (PNG), and hence a high incidence may also be expected in this population...
The relationship between undernutrition and humoral immune status in children with pneumonia in Papua New GuineaAllan W Cripps
School of Medicine, Griffith University, Gold Coast, Queensland, Australia
P N G Med J 51:120-30. 2008..is a significant risk factor for childhood infectious diseases in developing countries, including Papua New Guinea (PNG)...
Enzymatic hydrolysis of pyridoxine-5'-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolaseAmy D Mackey
Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611, USA
J Biol Chem 277:26858-64. 2002An obligatory step in the mammalian nutritional utilization of pyridoxine-5'-beta-D-glucoside (PNG) is the intestinal hydrolysis of its beta-glucosidic bond that releases pyridoxine (PN)...
AIDS in Papua New Guinea: situation in the PacificJohn C Caldwell
Health Transition Centre, National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT
J Health Popul Nutr 20:104-11. 2002..to anticipate a major heterosexual epidemic of acquired immunodeficiency syndrome (AIDS) in Papua New Guinea (PNG) and probably in the rest of Melanesia...
Biological activity evaluation of the oils from Laurus nobilis of Tunisia and Algeria extracted by supercritical carbon dioxideHanen Marzouki
Departement de Biologie, Faculte des Sciences de Tunis, Laboratoire de Botanique et de Biologie Végétal, Université de Tunis El Manar, Tunis, Tunisia
Nat Prod Res 23:230-7. 2009..0 MPa, one further extraction at 323.15 K and 24.0 MPa was performed to obtain a mixture of compounds with higher molecular weight. Finally, the antibacterial and antifungal activity of the various extracts has been assayed...
A rapid situation assessment of drug use in Papua New GuineaDavid McDonald
National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia
Drug Alcohol Rev 24:79-82. 2005Papua New Guinea (PNG) is an Asia Pacific country that we hear little about in the drug and alcohol area...
The first year of a formal emergency medicine training programme in Papua New GuineaChris Curry
School of Medicine and Health Sciences, University of Papua New Guinea and the Port Moresby General Hospital, Port Moresby, Papua New Guinea
Emerg Med Australas 16:343-7. 2004To describe a programme catalyzing the development of emergency medicine in Papua New Guinea (PNG).
Fungal colonization of sago starch in Papua New GuineaA R Greenhill
School of Veterinary and Biomedical Sciences, James Cook University, Townsville, QLD, Australia
Int J Food Microbiol 119:284-90. 2007..including Aspergillus and Penicillium were commonly isolated from sago starch, and as such storage factors that influence the growth of these and other filamentous fungi might contribute to the safety of traditional sago starch in PNG.
Vitamin B-6 status indicators decrease in women consuming a diet high in pyridoxine glucosideC M Hansen
Department of Nutrition and Food Management, Oregon State University, Corvallis 97331, USA
J Nutr 126:2512-8. 1996Previous research has shown that the pyridoxine glucoside (PNG) form of vitamin B-6 has a reduced bioavailability compared with pyridoxine, but its effect on vitamin B-6 status has not been assessed...
Estimating rainforest biomass stocks and carbon loss from deforestation and degradation in Papua New Guinea 1972-2002: Best estimates, uncertainties and research needsJane Bryan
School of Geography and Environmental Studies, University of Tasmania, Private Bag 78, Hobart, Tasmania 7001, Australia
J Environ Manage 91:995-1001. 2010..In Papua New Guinea (PNG), which has one of the world's largest remaining areas of tropical forest, we used the best available data to ..
Evidence of primary transmission of multidrug-resistant tuberculosis in the Western Province of Papua New GuineaChristopher M Gilpin
Mycobacterium Reference Laboratory, Pathology Queensland, Brisbane, QLD, Australia
Med J Aust 188:148-52. 2008To review patient outcomes and the molecular epidemiology of multidrug-resistant tuberculosis (MDR-TB) strains isolated from patients living in the Western Province of Papua New Guinea (PNG) seeking treatment in Australia.
Effect of distal subtotal gastrectomy with preservation of the celiac branch of the vagus nerve to gastrointestinal function: an experimental study in conscious dogsHiroyuki Ando
Department of General Surgical Science and the 21st Century COE Program, Gunma University Graduate School of Medicine 3 39 22, Japan
Ann Surg 247:976-86. 2008..To evaluate the effects of distal subtotal gastrectomy with preservation of the celiac branch of the vagus nerve on gastrointestinal function...
Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New GuineaJeana T DaRe
Case Western Reserve University, Wolstein Research Building, Cleveland, OH 44106, USA
Malar J 6:34. 2007..Previous studies have shown that microsatellite (MS) haplotype variation can be used to study the evolution of CQR polymorphism and to characterize intra- and inter-population dispersal of CQR in Papua New Guinea (PNG).
Socio-economic factors associated with physique of adults of the Purari delta of the Gulf Province, Papua New GuineaS J Ulijaszek
Institute of Social and Cultural Anthropology, University of Oxford, UK
Ann Hum Biol 30:316-28. 2003..relationships between components of the modernization process, including experience of urban life, urban connectedness, education, and the nature and diversity of income sources on adult body size in a Papua New Guinea (PNG) population.
Analysis of serum and cerebrospinal fluid cytokine levels in subacute sclerosing panencephalitis in Papua New GuineaTakashi Ichiyama
Department of Pediatrics, Yamaguchi University School of Medicine, 1 1 1 Minamikogushi, Ube, Yamaguchi 755 8505, Japan
Cytokine 33:17-20. 2006..Subacute sclerosing panencephalitis (SSPE) is a rare progressive inflammatory disease characterized by the persistent infection of the brain by the measles virus. However, the immunological pathophysiology of SSPE is still unclear...
Molecular analysis of measles virus genome derived from SSPE and acute measles patients in Papua, New GuineaKenji Miki
Department of Neurology, Nihon University School of Medicine, Tokyo, Japan
J Med Virol 68:105-12. 2002..below the age of 20 years for subacute sclerosing panencephalitis (SSPE) has been reported from Papua New Guinea (PNG). In a more recent study, we have confirmed this unusual high incidence for Eastern Highlands Province (EHP) of PNG...
Benefits of routine immunizations on childhood survival in Tari, Southern Highlands Province, Papua New GuineaDeborah Lehmann
Papua New Guinea Institute of Medical Research, Goroka and Tari, Papua New Guinea
Int J Epidemiol 34:138-48. 2005..This study aimed to determine the effects of diphtheria-tetanus-whole-cell-pertussis (DTP), BCG, hepatitis B, and measles vaccines on mortality in the highlands of Papua New Guinea (PNG).
Burkitt lymphoma in Papua New Guinea--40 years onEvelyn Lavu
Division of Pathology, School of Medicine and Health Sciences, University of Papua New Guinea, Boroko, Papua New Guinea
Ann Trop Paediatr 25:191-7. 2005..Burkitt lymphoma is common in tropical Africa and Papua New Guinea, where it has been reported to account for 16% of all childhood malignancies...
Escherichia coli uracil DNA glycosylase: NMR characterization of the short hydrogen bond from His187 to uracil O2A C Drohat
Center for Advanced Research in Biotechnology of the National Institute of Standards and Technology and the University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA
Biochemistry 39:11865-75. 2000..The role of this H bond in catalysis by UDG and several approaches to quantify the H bond energy are discussed...
Antitreponemal antibodies leading to autoantibody production and protection from atherosclerosis in Kitavans from Papua New GuineaNancy Agmon-Levin
Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel
Ann N Y Acad Sci 1173:675-82. 2009..agent antibodies and autoantibodies in a unique non-Westernized population from Kitava, Papua New Guinea (PNG), compared to Western populations...
Screening of anti-Helicobacter pylori herbs deriving from Taiwanese folk medicinal plantsYuan Chuen Wang
Department of Food Science, National Chung Hsing University, 250 Kuokuang Road, Taichung 40227, Taiwan, 402, ROC
FEMS Immunol Med Microbiol 43:295-300. 2005..24 mg ml(-1). Twenty-six herbs, including Artemisia argvi Levl. et Vant (AALEV), Phyla nodiflora (Linn.) Greene (PNG) and others, showed moderate anti-H. pylori activity. The additional 19 herbs, including Areca catechu Linn...
Treatment-seeking behaviour among the Nasioi people of Bougainville: choosing between traditional and western medicineJoan Elizabeth Macfarlane
Curtin University of Technology, Centre for International Health, Perth, Australia
Ethn Health 14:147-68. 2009In Papua New Guinea (PNG) there continues to be considerable interest in developing a health system that incorporates both traditional and western medicine. A policy on traditional medicine has recently been endorsed...
Alpha+ -thalassaemia and pregnancy in a malaria endemic region of Papua New GuineaA O'DONNELL
Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, UK
Br J Haematol 135:235-41. 2006..effect of maternal alpha+ -thalassaemia on pregnancy was assessed in the north coastal region of Papua New Guinea (PNG), where malaria is hyperendemic and alpha+ -thalassaemia is extremely common...
Spontaneous fermentation of traditional sago starch in Papua New GuineaA R Greenhill
Environmental and Public Health Microbiology Research Group, School of Veterinary and Biomedical Sciences, James Cook University, Townsville, QLD, Australia
Food Microbiol 26:136-41. 2009Sago starch is an important dietary carbohydrate in lowland Papua New Guinea (PNG). An investigation was conducted to determine whether microbes play a role in its preservation using traditional methods...
Molecular evolution of fern squalene cyclasesJunichi Shinozaki
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Chembiochem 11:426-33. 2010..niponica was carried out. Two SCs (PNT and PNG) were obtained...
Emerging zoonotic encephalitis viruses: lessons from Southeast Asia and OceaniaJohn S Mackenzie
Australian Biosecurity CRC, Curtin University of Technology, Perth, Western Australia, Australia
J Neurovirol 11:434-40. 2005..virus (JEV), a mosquito-borne flavivirus, has spread through the Indonesian archipelago to Papua New Guinea (PNG) and to the islands of the Torres Strait of northern Australia, to Pakistan, and to new areas in the Indian ..
Glycophorin C delta(exon3) is not associated with protection against severe anaemia in Papua New GuineaL Tavul
Papua New Guinea Institute of Medical Research, Madang and Goroka, Papua New Guinea
P N G Med J 51:149-54. 2008..falciparum lines. The GYPCC delta(exon3) allele reaches high frequencies in two areas of Papua New Guinea (PNG) where malaria is highly endemic...
A sequence highly similar to PNG is located on chromosome 22q12 in intron 15 of the LIMK-2 geneD Kedra
Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
Biochem Mol Biol Int 44:589-94. 1998In this report we describe a sequence (PNG22) highly similar to the Phospholipase C beta3 Neighboring Gene (PNG). We also report that PNG22 is located in the q12 region on chromosome 22 between markers D22S1144 and D22S280...
Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: role of neurotoxic and procoagulant effects in venom toxicityMaria Herrera
Instituto Clodomiro Picado, Universidad de Costa Rica, San Jose, Costa Rica
J Proteomics 75:2128-40. 2012..of populations of the highly venomous taipan snake, Oxyuranus scutellatus, from Australia and Papua New Guinea (PNG), were characterized by reverse-phase HPLC fractionation, followed by analysis of chromatographic fractions by SDS-..
Intraspinal microinjection of chondroitinase ABC following injury promotes axonal regeneration out of a peripheral nerve graft bridgeVeronica J Tom
Department of Neurobiology and Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA
Exp Neurol 211:315-9. 2008..ChABC) via an osmotic minipump allowed axonal regeneration and functional recovery in a peripheral nerve graft (PNG)-bridging model...
Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populationsRajeev K Mehlotra
Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
Eur J Clin Pharmacol 63:1-8. 2007..Our aim was to analyze the prevalence of UGT1A9 (chromosome 2) and UGT2B7 (chromosome 4) nonsynonymous single nucleotide polymorphisms (SNPs) in West African (WA), Papua New Guinean (PNG), and North American (NA) populations.
Robert Koch redux: malaria immunology in Papua New GuineaD I Stanisic
The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic, Australia
Parasite Immunol 32:623-32. 2010..microbiologist Robert Koch to the Dutch East Indies (Indonesia) and German New Guinea (now Papua New Guinea, or PNG), resulted in profound observations that are still central to our current understanding of the epidemiology and ..
Malaria vectors of Papua New GuineaR D Cooper
Australian Army Malaria Institute, Gallipoli Barracks, Enoggera, Qld 4052, Australia
Int J Parasitol 39:1495-501. 2009Understanding malaria transmission in Papua New Guinea (PNG) requires exact knowledge of which Anopheles species are transmitting malaria and is complicated by the cryptic species status of many of these mosquitoes...
Strain-specific duffy binding protein antibodies correlate with protection against infection with homologous compared to heterologous plasmodium vivax strains in Papua New Guinean childrenJennifer L Cole-Tobian
Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio 44106, USA
Infect Immun 77:4009-17. 2009..Antibodies directed to PvDBPII PNG-P and -O were both associated with a 21 to 26% reduction in the risk of P...
Fluxviz - cytoscape plug-in for visualization of flux distributions in networksMatthias König
Institute of Biochemistry, Medical Faculty of the Humboldt University, Charite, Monbijoustr 2, 10117 Berlin, Germany
Genome Inform 24:96-103. 2010..flux subnetwork) or network attributes like localization (iv) export of generated views (SVG, EPS, PDF, BMP, PNG)...
Gendered talk about sex, sexual relationships and HIV among young people in Papua New GuineaAngela Kelly
Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea
Cult Health Sex 12:221-32. 2010..from a qualitative study carried out in three secondary schools in Eastern Highlands Province, Papua New Guinea (PNG)...
An efficient fluorescence resonance energy transfer (FRET) between pyrene and perylene assembled in a DNA duplex and its potential for discriminating single-base changesHiromu Kashida
Graduate School of Engineering, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan
Chemistry 16:2479-86. 2010..In contrast, excimer emission was generated by hybridization with a one-base deletion mutant. Thus, the apparent Stokes' shift was enhanced without loss of efficiency in the detection of the deletion mutant...
Neonatal innate cytokine responses to BCG controlling T-cell development vary between populationsAnita H J van den Biggelaar
Telethon Institute for Child Health Research, Center for Child Health Research, University of Western Australia, Perth, Australia
J Allergy Clin Immunol 124:544-50, 550.e1-2. 2009..The protective effect of Mycobacterium bovis BCG vaccination against infection and atopy varies between populations...
Design of a laboratory for experiments with a pulsed neutron sourceG Memoli
Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UK
J Radiol Prot 29:183-200. 2009..study performed to reduce the exposure to radiological doses arising from a 14 MeV pulsed neutron generator (PNG) having a maximum emission strength of 2.0 x 10(8) neutrons s(-1)...
Neuroprotection in traumatic brain injury: practical implications for Papua New Guinea and some research developmentsW Matui Kaptigau
Department of Surgery, Port Moresby General Hospital, Free Mail Bag, Boroko, NCD 111, Papua New Guinea
P N G Med J 50:67-71. 2007Given the lack of infrastructure in Papua New Guinea (PNG) traumatic brain injury (TBI) cases are usually not retrieved quickly to medical centres. Cases that eventually reach the hospital do so after the golden hour has passed...
Quantitative analysis of valiolamine through pre-column derivatization with phenylisocyanate using high-performance liquid chromatography with UV detection: selection of reagent, identification of derivative and optimization of derivatization conditionsHe Li
Department of Chemical and Biological Engineering and ERI, Gyeongsang National University, Jinju, Gyeongnam, Republic of Korea
J Pharm Biomed Anal 49:957-63. 2009..9-99.7 microg/mL for the spiked sample. The proposed method was validated and proven to be selective, accurate and precise and suitable for the quantitative analysis of valiolamine in medium for microbial cultures...
Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cellsFionnuala Ni Ainle
Haemostasis Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin 2, Ireland
J Biol Chem 286:1323-30. 2011..Enzymatic digestion of APC N-linked glycans (PNG-APC) decreased the APC concentration required to achieve half-maximal inhibition of thrombin-induced endothelial ..
An evaluation of information-theoretic methods for detecting structural microbial biosignaturesKiri L Wagstaff
Machine Learning and Instrument Autonomy Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109, USA
Astrobiology 10:363-79. 2010..However, the PNG compression ratio provided the strongest distinction (2...
Quenching of singlet oxygen by pyocyanin and related phenazinesKrzysztof J Reszka
Research Service and Medical Service, VA Medical Center, Cincinnati, OH, USA
Photochem Photobiol 86:742-6. 2010..aeruginosa from infected tissues...
Reference intervals for common laboratory tests in Melanesian childrenLaurens Manning
School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia
Am J Trop Med Hyg 85:50-4. 2011..The aim of this study was to provide specific reference intervals for children from Papua New Guinea (PNG)...
Incomplete concerted evolution and reproductive isolation at the rDNA locus uncovers nine cryptic species within Anopheles longirostris from Papua New GuineaDavid E Alquezar
Institute for the Biotechnology of Infectious Disease, University of Technology, Sydney Australia
BMC Evol Biol 10:392. 2010..DNA cytochrome oxidase I subunit in the malaria mosquito Anopheles longirostris from Papua New Guinea (PNG)...
"When the road is full of potholes, I wonder why they are bringing condoms?" Social spaces for understanding young Papua New Guineans' health-related knowledge and health-promoting actionCathy Vaughan
Institute of Social Psychology, London School of Economics, London, UK
AIDS Care 22:1644-51. 2010As in many other parts of the world, young people in Papua New Guinea (PNG) are considered particularly vulnerable to HIV infection...
Barriers to the delivery of the hepatitis B birth dose: a study of five Papua New Guinean hospitals in 2007S G Downing
Centre for Epidemiology and Population Health Research, Macfarlane Burnet Institute for Medical Research and Public Health, GPO Box 2284, Melbourne, Victoria 3001, Australia
P N G Med J 51:47-55. 2008Hepatitis B is highly endemic in Papua New Guinea (PNG). Vaccination at birth is a key mother-to-child transmission prevention strategy...
Lymphatic filariasis: a method to identify subclinical lower limb change in PNG adolescentsSusan Gordon
School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Australia
PLoS Negl Trop Dis 5:e1242. 2011..proposed that this cut-off can be used to indicate tissue change characteristic of LF in an at-risk population of PNG adolescents...
Methods from the theory of random heterogeneous media for quantifying myocardial morphology in normal and dilated heartsRudolf Karch
Department of Medical Statistics and Informatics, Medical University of Vienna, Spitalgasse 23, A 1090, Vienna, Austria
Ann Biomed Eng 38:308-18. 2010....
Metronidazole resistance in Trichomonas vaginalis from highland women in Papua New GuineaJacqueline A Upcroft
Queensland Institute of Medical Research, The Bancroft Centre, 300 Herston Road, Brisbane, QLD 4006, Australia
Sex Health 6:334-8. 2009..of the sexually transmissible protozoan parasite Trichomonas vaginalis in the highlands of Papua New Guinea (PNG) has been reported to be as high as 46% and although not previously studied in Papua New Guinea, clinical ..
Altered growth patterns of a mountain Ok population of Papua New Guinea over 25 years of changeAmita Adhikari
Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan 48109 5622, USA
Am J Hum Biol 23:325-32. 2011The Mountain Ok (Mt Ok) people of Telefomin, who live at the interior of Papua New Guinea (PNG), were documented over 25 years ago to be one of the shortest populations on record, with average adult height below the fifth percentile (US)...
Persistence as the path from motivation to performance in the Papua New Guinea health sectorLuke Elich
Capacity Building Service Centre, Port Moresby, Papua New Guinea
P N G Med J 52:159-65. 2009..between performance and the human-resource-mediating variables, which is then applied within the Papua New Guinea (PNG) health sector context...
Peripheral nerve grafts after cervical spinal cord injury in adult catsMarie Pascale Côté
Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
Exp Neurol 225:173-82. 2010Peripheral nerve grafts (PNG) into the rat spinal cord support axon regeneration after acute or chronic injury, with synaptic reconnection across the lesion site and some level of behavioral recovery...
Beyond the numbers: Papua New Guinean perspectives on the major health conditions and programs of the countryMaxine Whittaker
School of Population Health, University of Queensland, Brisbane, Australia
P N G Med J 52:96-113. 2009..behaviours amongst a range of urban and rural populations in a range of provinces in Papua New Guinea (PNG), and across a range of age groups including young adults...
Sequence analysis of Leuconostoc mesenteroides bacteriophage Phi1-A4 isolated from an industrial vegetable fermentationZ Lu
Kennesaw State University, 1000 Chastain Road, Kennesaw, GA 30144, USA
Appl Environ Microbiol 76:1955-66. 2010..To our knowledge, Phi1-A4 is the first genetically characterized L. mesenteroides phage...
Tuberculosis in Australia: bacteriologically confirmed cases and drug resistance, 2008 and 2009. A report of the Australian Mycobacterium Reference Laboratory NetworkRichard Lumb
Microbiology and Infectious Diseases Directorate, SA Pathology, Adelaide, South Australia
Commun Dis Intell Q Rep 35:154-61. 2011..There were six and 11 MDR-TB patients from the Papua New Guinea (PNG) - Torres Strait Islands (TSI) cross-border region in 2008 and 2009 respectively...
Evolutionary history of the COII/tRNALys intergenic 9 base pair deletion in human mitochondrial DNAs from the PacificA J Redd
Department of Anthropology, Pennsylvania State University, University Park 16802, USA
Mol Biol Evol 12:604-15. 1995..We obtained CR sequences from 74 mtDNAs with the 9-bp deletion from Indonesia, coastal Papua New Guinea (PNG), and American Samoa...
A surveillance information system as a management tool: a report from Papua New GuineaGilbert Hiawalyer
Monitoring and Research Branch, Department of Health, NCD, Papua New Guinea
Soz Praventivmed 50:S31-2. 2005..In Papua New Guinea (PNG) a national health information system was developed, trailed and implemented nationwide...
N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21Yu bo Zhou
College of Life Science and Biotechnology, Shanghai Jiaotong University, 1954 Huashan Road, Shanghai 200030, China
FEBS Lett 576:401-7. 2004..define whether the glycosylation was important process for its secretion, endoglycosidase H (Endo H) and PNGase F (PNG F) were employed to evaluate the effect of glycosylation types on secretion of hPAP21...
Analysis of cell-cycle kinetics and sulfur amino acid metabolism in methionine-dependent tumor cell lines; the effect of homocysteine supplementationValerie Pavillard
School of Pharmacy, University of Bradford, Bradford BD7 1DP, UK
Biochem Pharmacol 67:1587-99. 2004..The information resulting from these studies is important for not only the behavior of cancer cells, but also for appreciating the potential of developing cancer therapies based on methionine-depletion strategies...
Partial amino acid sequence and mRNA analysis of cytosolic pyridoxine-beta-D-glucoside hydrolase from porcine intestinal mucosa: proposed derivation from the lactase-phlorizin hydrolase geneChi Wah Tseung
Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611 0370, USA
Biochem J 380:211-8. 2004..PNGH catalyses the hydrolysis of PNG (pyridoxine-5'-beta-D-glucoside), a plant derivative of vitamin B6 that exhibits partial nutritional ..
Phosphorylation of protein phosphatase type-1 inhibitory proteins by integrin-linked kinase and cyclic nucleotide-dependent protein kinasesFerenc Erdodi
Department of Medical Chemistry, Medical and Health Science Center, University of Debrecen, H 4012 Debrecen, 18 B, Bem ter, Hungary
Biochem Biophys Res Commun 306:382-7. 2003..1 nM) and MPH (IC(50)=8 nM). These results suggest that the regulatory phosphorylation of CPI-17 and KEPI may involve distinct kinases and signaling pathways...
Population structure and dispersal of the freshwater mosquitoes Culex annulirostris and Culex palpalis (Diptera: Culicidae) in Papua New Guinea and northern AustraliaH F Chapman
Queensland Institute of Medical Research and University of Queensland Tropical Health Program, P O Royal Brisbane Hospital, Queensland 4029, Australia
J Med Entomol 40:165-9. 2003..The results have demonstrated that in the region incorporating Western Province in PNG, the Torres Strait and Cape York Peninsula, Cx...
Reduced Y-chromosome, but not mitochondrial DNA, diversity in human populations from West New GuineaManfred Kayser
Department for Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Am J Hum Genet 72:281-302. 2003..183 individuals from 11 regional populations of West New Guinea (WNG) and 131 individuals from Papua New Guinea (PNG) were analyzed at 26 binary markers and seven short-tandem-repeat loci from the nonrecombining part of the human Y ..
Ribosomal DNA spacer genotypes of the Anopheles bancroftii group (Diptera: Culicidae) from Australia and Papua New GuineaN W Beebe
Department of Cell and Molecular Biology, University of Technology Sydney, Australia
Insect Mol Biol 10:407-13. 2001Mosquitoes of the Anopheles bancroftii group collected from Northern Australia and Papua New Guinea (PNG) were investigated for sequence variation within the ribosomal DNA ITS2...
Old World screwworm fly, Chrysomya bezziana, occurs as two geographical racesM J Hall
Department of Entomology, The Natural History Museum, London, UK
Med Vet Entomol 15:393-402. 2001..components and cluster analysis of 10 morphological characters indicated that flies from Papua New Guinea (PNG) were a distinct group and most similar to flies from nearby Asian islands (Java, Sabah)...
Emergence of FY*A(null) in a Plasmodium vivax-endemic region of Papua New GuineaP A Zimmerman
Division of Geographic Medicine, Case Western Reserve School of Medicine, 2109 Adelbert Road, Cleveland, OH 44106 4983, USA
Proc Natl Acad Sci U S A 96:13973-7. 1999In Papua New Guinea (PNG), numerous blood group polymorphisms and hemoglobinopathies characterize the human population...
Orbital malignancy in Papua New Guinea: a 21 year reviewN Verma
Port Moresby General Hospital, Boroko, National Capital District, Papua New Guinea
Aust N Z J Ophthalmol 27:27-31. 1999Information about orbital malignancies in Papua New Guinea (PNG) is limited to reports published 20 years ago...
Mytilus protamine-like sperm-specific protein genes are multicopy, dispersed, and closely associated with hypervariable RFLP regionsD D Heath
Biology Program, College of Science and Management, University of Northern British Columbia, Canada
Genome 41:587-96. 1998..described here was designed to determine the sequence and structure of the protamine-like PL-III (or "phi 1") gene in marine mussels (Mytilus spp)...
Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigenS H Qari
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Mol Biochem Parasitol 92:241-52. 1998..Based on the amino acid substitution, four known alleles, E-TSR (PNG-MAD20 type), E-KNG (Uganda-PA type), Q-KNG (Wellcome type), and Q-TSR (Indo type) of this domain have been ..
[Control of photocoagulation intensity by thermo-induced release of a fluorescent marker encapsulated in liposomes: study of an in vivo vascular model]T Desmettre
INSERM Unite 279, CH and U, Lille
J Fr Ophtalmol 19:667-78. 1996..To evaluate the feasibility of thermal damage assessment of blood vessels by using laser-induced release of liposome-encapsulated dye...
Molecular dynamics simulation of conformational flexibility of alamethicin fragments in aqueous and membranous environmentV Kothekar
Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India
J Biomol Struct Dyn 14:303-16. 1996..In case of alam 2 in water angles phi 1 and phi 3 showed larger variation in water compared to same in the bilayer...
Sequence and expression of the mouse homologue to human phospholipase C beta3 neighboring geneJ Lagercrantz
Department of Molecular Medicine, Clinical Genetics Unit, Karolinska Hospital, Stockholm, Sweden
Biochem Biophys Res Commun 223:335-40. 1996..The PNG cDNA was isolated using a human PNG cDNA clone (SOM172)...
Temperature dependence of collagen fluorescenceJulian M Menter
Department of Medicine, Morehouse School of Medicine, 720 Westview Dr S W, Atlanta, GA 30310 1495, USA
Photochem Photobiol Sci 5:403-10. 2006....
Research Grants
- Modeling lymphatic filariasis transmission and eradication in Papua New GuineaEdwin Michael; Fiscal Year: 2007..anopheline mosquitoes and its control using annual mass drug administration (MDA) strategies in Papua New Guinea (PNG) and elsewhere, and to develop and apply effective model-based decision support tools for optimizing the design and ..
- Modeling lymphatic filariasis transmission and eradication in Papua New GuineaEdwin Michael; Fiscal Year: 2010..anopheline mosquitoes and its control using annual mass drug administration (MDA) strategies in Papua New Guinea (PNG) and elsewhere, and to develop and apply effective model-based decision support tools for optimizing the design and ..
- PAPUA NEW GUINEAN DUFFY NEGATIVITY AND VIVAX MALARIAPeter Zimmerman; Fiscal Year: 2005..is that the molecular polymorphism responsible for Duffy-negativity (Fy[a-b-1) has emerged in Papua New Guinea (PNG) because it confers resistance to Plasmodium vivax blood-stage malaria...
- Changing Dynamics of Anopheline Transmission of Malaria and Filariasis in Papua nPeter A Zimmerman; Fiscal Year: 2010..landscape heterogeneity of plant, animal, and human communities in four ecologically different sites in northern PNG. 2. Examine the change in patterns of mosquito and human infection with Plasmodium species and with W...
- Changing Dynamics of Anopheline Transmission of Malaria and Filariasis in Papua nPeter Zimmerman; Fiscal Year: 2007..landscape heterogeneity of plant, animal, and human communities in four ecologically different sites in northern PNG. 2. Examine the change in patterns of mosquito and human infection with Plasmodium species and with W...
- Changing Dynamics of Anopheline Transmission of Malaria and Filariasis in Papua nPeter Zimmerman; Fiscal Year: 2007..landscape heterogeneity of plant, animal, and human communities in four ecologically different sites in northern PNG. 2. Examine the change in patterns of mosquito and human infection with Plasmodium species and with W...
- Changing Dynamics of Anopheline Transmission of Malaria and Filariasis in Papua nPeter Zimmerman; Fiscal Year: 2009..landscape heterogeneity of plant, animal, and human communities in four ecologically different sites in northern PNG. 2. Examine the change in patterns of mosquito and human infection with Plasmodium species and with W...
- GENETIC POLYMORPHISMS AND DIVERSITY IN MALARIADyann Wirth; Fiscal Year: 2003..will be identified in a large set of well-characterized parasite isolates from Brazil, Thailand, Papua New Guinea (PNG) and Tanzania...
- Recovery of bladder reflexes and nerve regeneration after spinal cord injuryYu Shang Lee; Fiscal Year: 2010..that could allow for the resumption of supraspinal control of bladder activity utilizes peripheral nerve grafting (PNG) to provide a favorable environment for axonal regeneration and remyelination in order to bridge the lesion gap...
- CELL CYCLE CONTROL IN EARLY DROSOPHILA DEVELOPMENTTerry L Orr Weaver; Fiscal Year: 2010..The PAN GU (PNG) protein kinase complex regulates the early embryonic cycles by promoting translation of Cyclin B to drive mitosis...
- RIGID PROBES: MODELING SELECTIVE ANXIOLYTICS FOR BZRJames Cook; Fiscal Year: 1993..domain (see Figures 4-8) at lipophilic regions, as well as the importance of electron density on the ligands at phi 1 and phi 2. These agents will be synthesized and then tested in vitro and in vivo (mice/rats) for their efficacy...
- NUTRITIONAL PROPERTIES OF PYRIDOXINE-BETA-GLUCOSIDEJESSE GREGORY; Fiscal Year: 2001DESCRIPTION: Pyridoxine-beta-glucoside (PNG) is a major component of vitamin B6 (B6) in plant foods, and PNG hydrolysis catalyzed by PNG hydrolase is rate limiting for the in vivo utilization...
- CELL CYCLE CONTROL IN EARLY DROSOPHILA DEVELOPMENTTerry Orr Weaver; Fiscal Year: 2000..Two genes have been identified, plutonium (plu) and pan gu (png), that regulate DNA replication at the onset of development...
- REPLICATION AND POLYTENIZATION IN DROSOPHILA DEVELOPMENTTerry Orr Weaver; Fiscal Year: 1993..Two genes have been identified, plutonium (plu) and pan gu (png), that regulate DNA replication at the onset of development...
- CELL CYCLE CONTROL IN EARLY DROSOPHILA DEVELOPMENTTerry Orr Weaver; Fiscal Year: 2004..The PAN GU (PNG) protein kinase is required specifically to promote mitosis and limit DNA replication during the S-M cycles...
- Regulation Vascular Smooth Muscle Myosin PhosphataseMasumi Eto; Fiscal Year: 2010..Relevance) Drugs, blocking the contraction, are used for treatment of hypertension, asthma and erectile dysfunction. The results of this project will expose potential therapeutic targets for smooth muscle diseases. ..
- Molecular Mechanisms for Regulation of Vascular Smooth Muscle Myosin PhosphataseMasumi Eto; Fiscal Year: 2007..Relevance) Drugs, blocking the contraction, are used for treatment of hypertension, asthma and erectile dysfunction. The results of this project will expose potential therapeutic targets for smooth muscle diseases. ..
- Chloroquine Resistance and pfcrt Variants in PNGPeter Zimmerman; Fiscal Year: 2006..Malaria is the leading cause of morbidity and mortality in PNG, and as drug treatment is the only effective means of control for clinical malaria, an improved understanding of ..
- Developmental Regulation of the Cell Cycle in DrosophilaLaura Lee; Fiscal Year: 2009..are required for regulation of the streamlined "S-M" cycles characteristic of this developmental stage: pan gu (png), plutonium (plu), and giant nuclei (gnu)...
