peroxisomal 2 4 dienoyl CoA reductase


Gene Symbol: peroxisomal 2 4 dienoyl CoA reductase
Description: 2,4-dienoyl-CoA reductase 2
Alias: PDCR, SDR17C1, peroxisomal 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase 2, peroxisomal, short chain dehydrogenase/reductase family 17C member 1
Species: human

Top Publications

  1. Hua T, Wu D, Ding W, Wang J, Shaw N, Liu Z. Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids. J Biol Chem. 2012;287:28956-65 pubmed publisher
    ..Here, we describe the crystal structure of a ternary complex of peroxisomal 2,4-dienoyl CoA reductases (pDCR) with hexadienoyl CoA and NADP, as a prototype for comparison with the mitochondrial 2,4-dienoyl CoA reductase (..
  2. Duan H, Xu C. Nanoporous PdCr alloys as highly active electrocatalysts for oxygen reduction reaction. Phys Chem Chem Phys. 2016;18:4166-73 pubmed publisher
    A simple and convenient dealloying method is used to prepare nanoporous (NP) PdCr alloys with uniform ligament dimensions and controllable bimetallic ratio...
  3. Steele T, Wilson M, Strong E. Ultrasonic bone aspirator assisted endoscopic dacryocystorhinostomy. Am J Otolaryngol. 2016;37:202-6 pubmed publisher
    ..Twenty nine patients underwent powered microdrill DCR (pDCR); 34 patients underwent ultrasonic bone aspirator DCR (uDCR)...
  4. Schmalenberg H, Al Batran S, Pauligk C, Zander T, Reichart A, Lindig U, et al. CabaGast: multicentre, Phase II study with cabazitaxel in previously treated patients with advanced or metastatic adenocarcinoma of the esophagogastric junction and stomach. J Cancer Res Clin Oncol. 2018;144:559-569 pubmed publisher
    ..The main objective of the study is a prolonged disease control rate (pDCR: CR, PR or SD lasting at least 4 months)...
  5. Das A, Uhler M, Hajra A. Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs. J Biol Chem. 2000;275:24333-40 pubmed publisher
    ..Northern blot analysis demonstrated that a single transcript of 1.3 kilobases is present in most mouse tissues, with particularly high concentrations in liver and kidney...
  6. De Nys K, Meyhi E, Mannaerts G, Fransen M, Van Veldhoven P. Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase. Biochim Biophys Acta. 2001;1533:66-72 pubmed
    ..Hence, the reductase does not seem to constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. The reduction of docosaheptaenoyl-CoA, however, was severely decreased in the presence of albumin. ..