PAPST2

Summary

Gene Symbol: PAPST2
Description: solute carrier family 35 member B3
Alias: C6orf196, CGI-19, PAPST2, adenosine 3'-phospho 5'-phosphosulfate transporter 2, 3' phosphoadenosine 5' phosphosulfate transporter 2, PAPS transporter 2, solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
Species: human
Products:     PAPST2

Top Publications

  1. Palmer N, Goodarzi M, Langefeld C, Wang N, Guo X, Taylor K, et al. Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 2015;64:1853-66 pubmed publisher
    ..These results suggest that T2D and insulin secretion and sensitivity have both shared and distinct genetic factors, potentially delineating genomic components of these quantitative traits that drive the risk for T2D. ..
  2. Ashykhmina N, Lorenz M, Frerigmann H, Koprivova A, Hofsetz E, Stührwohldt N, et al. PAPST2 Plays Critical Roles in Removing the Stress Signaling Molecule 3'-Phosphoadenosine 5'-Phosphate from the Cytosol and Its Subsequent Degradation in Plastids and Mitochondria. Plant Cell. 2019;31:231-249 pubmed publisher
    ..We investigated the activity of PAPST2, the closest homolog of PAPST1, which unlike PAPST1 is targeted to both the plastids and mitochondria...
  3. Kamiyama S, Sasaki N, Goda E, Ui Tei K, Saigo K, Narimatsu H, et al. Molecular cloning and characterization of a novel 3'-phosphoadenosine 5'-phosphosulfate transporter, PAPST2. J Biol Chem. 2006;281:10945-53 pubmed
    ..This gene, called PAPST2, is predominantly expressed in human colon tissues...
  4. Li D, Song Y, Zhan Q. [Specifically up-regulated non-coding RNA gene HULC in tumor cell lines and its effects on the expression of neighboring gene SLC35B3]. Zhonghua Yi Xue Za Zhi. 2010;90:3156-9 pubmed
    ..283 ± 0.007)%, siB (0.387 ± 0.015)%, control (0.477 ± 0.042)%]. The specifically up-regulated non-coding gene HULC in HepG2 cell line has some effects on the expression of its neighboring gene SLC35B3. ..
  5. Goren A, Ram O, Amit M, Keren H, Lev Maor G, Vig I, et al. Comparative analysis identifies exonic splicing regulatory sequences--The complex definition of enhancers and silencers. Mol Cell. 2006;22:769-81 pubmed
    ..This finding signifies the delicate positional effect of ESRs on alternative splicing regulation. ..
  6. Kamiyama S, Ichimiya T, Ikehara Y, Takase T, Fujimoto I, Suda T, et al. Expression and the role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma. Glycobiology. 2011;21:235-46 pubmed publisher
    ..The relative amount of PAPST1 transcripts was found to be higher than those of PAPST2 in colorectal cancerous tissues...