p115

Summary

Gene Symbol: p115
Description: USO1 vesicle transport factor
Alias: P115, TAP, VDP, general vesicular transport factor p115, USO1 vesicle docking protein homolog, transcytosis associated protein, vesicle docking protein p115
Species: human
Products:     p115

Top Publications

  1. Nelson D, Alvarez C, Gao Y, Garcia Mata R, Fialkowski E, Sztul E. The membrane transport factor TAP/p115 cycles between the Golgi and earlier secretory compartments and contains distinct domains required for its localization and function. J Cell Biol. 1998;143:319-31 pubmed
    The mammalian protein TAP/p115 and its yeast homologue Uso1p have an essential role in membrane traffic (Nakajima et al., 1991; Waters et al., 1992; Sztul et al., 1993; Rabouille et al.; 1995)...
  2. Malsam J, Satoh A, Pelletier L, Warren G. Golgin tethers define subpopulations of COPI vesicles. Science. 2005;307:1095-8 pubmed
    ..The p115-golgin tether is the best studied, and here we characterize the golgin-84-CASP tether...
  3. Striegl H, Roske Y, Kümmel D, Heinemann U. Unusual armadillo fold in the human general vesicular transport factor p115. PLoS ONE. 2009;4:e4656 pubmed publisher
    ..The golgin p115 is targeted by the GTPase Rab1a, contains a large globular head region and a long region of coiled-coil which forms ..
  4. Waters M, Clary D, Rothman J. A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack. J Cell Biol. 1992;118:1015-26 pubmed
    ..The result is a protein of 115-kD subunit molecular mass, which we term p115. Immunodepletion of the 115-kD protein from a purified preparation with mAbs removes activity...
  5. Nakamura N, Lowe M, Levine T, Rabouille C, Warren G. The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner. Cell. 1997;89:445-55 pubmed
    The docking of transport vesicles with their target membrane is thought to be mediated by p115. We show here that GM130, a cis-Golgi matrix protein, interacts specifically with p115 and so could provide a membrane docking site...
  6. Short B, Haas A, Barr F. Golgins and GTPases, giving identity and structure to the Golgi apparatus. Biochim Biophys Acta. 2005;1744:383-95 pubmed
    ..Similarly, other golgins such as the vesicle tethering factor p115 and Bicaudal-D are targeted by the Rab GTPases, Rab1 and Rab6, respectively...
  7. Sohda M, Misumi Y, Yoshimura S, Nakamura N, Fusano T, Ogata S, et al. The interaction of two tethering factors, p115 and COG complex, is required for Golgi integrity. Traffic. 2007;8:270-84 pubmed
    The vesicle-tethering protein p115 functions in endoplasmic reticulum-Golgi trafficking. We explored the function of homologous region 2 (HR2) of the p115 head domain that is highly homologous with the yeast counterpart, Uso1p...
  8. Allan B, Moyer B, Balch W. Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science. 2000;289:444-8 pubmed
    ..Here, the tethering factor p115 was shown to be a Rab1 effector that binds directly to activated Rab1...
  9. Dirac Svejstrup A, Shorter J, Waters M, Warren G. Phosphorylation of the vesicle-tethering protein p115 by a casein kinase II-like enzyme is required for Golgi reassembly from isolated mitotic fragments. J Cell Biol. 2000;150:475-88 pubmed
    ..transport vesicles can be tethered to Golgi membranes by a complex of fibrous, coiled-coil proteins comprising p115, Giantin and GM130...

More Information

Publications131 found, 100 shown here

  1. Puthenveedu M, Linstedt A. Gene replacement reveals that p115/SNARE interactions are essential for Golgi biogenesis. Proc Natl Acad Sci U S A. 2004;101:1253-6 pubmed
    ..Here, we use functional replacement of the vesicle docking protein p115 to separate its essential from its nonessential interactions...
  2. Guo Y, Punj V, Sengupta D, Linstedt A. Coat-tether interaction in Golgi organization. Mol Biol Cell. 2008;19:2830-43 pubmed publisher
    ..residues yielded a defect in Golgi organization reminiscent of that occurring in the absence of the vesicle tether p115. Indeed, betaCOP bound p115, and this depended on the betaCOP FW motif...
  3. Sohda M, Misumi Y, Yano A, Takami N, Ikehara Y. Phosphorylation of the vesicle docking protein p115 regulates its association with the Golgi membrane. J Biol Chem. 1998;273:5385-8 pubmed
    The vesicle docking protein p115 was found to be phosphorylated in a cell cycle-specific manner; it was found phosphorylated in interphase but not in mitotic cells...
  4. Sohda M, Misumi Y, Yoshimura S, Nakamura N, Fusano T, Sakisaka S, et al. Depletion of vesicle-tethering factor p115 causes mini-stacked Golgi fragments with delayed protein transport. Biochem Biophys Res Commun. 2005;338:1268-74 pubmed
    Depletion of p115 with small interfering RNA caused fragmentation of the Golgi apparatus, resulting in dispersed distribution of stacked short cisternae and a vesicular structure (mini-stacked Golgi)...
  5. Saleem S, Khan R, Afzal M, Kazmi I. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/?-catenin signaling pathway. Mol Cell Biochem. 2018;444:187-196 pubmed publisher
    ..1% in tap water) for promoting tumorigenesis throughout the study. MTX (2.5 and 5...
  6. Oyagbemi A, Omobowale T, Asenuga E, Adejumobi A, Ajibade T, Ige T, et al. Sodium fluoride induces hypertension and cardiac complications through generation of reactive oxygen species and activation of nuclear factor kappa beta. Environ Toxicol. 2017;32:1089-1101 pubmed publisher
    ..Group A received clean tap water...
  7. Ali D, El Sayyad H, Moftah O, Chilibeck P. Structural and functional abnormalities of hepatic tissues in male Wistar rats fed hyperwhey and super amino anabolic protein. Nutrition. 2016;32:840-8 pubmed publisher
    ..Launderale, FL, USA) (2.5 g/kg body weight). The applied dose was orally administered daily in tap water for 14 wk. Body weight was regularly measured. At 14 wk, animals were sacrificed and dissected...
  8. Huc T, Jurkowska H, Wróbel M, Jaworska K, Onyszkiewicz M, Ufnal M. Colonic hydrogen sulfide produces portal hypertension and systemic hypotension in rats. Exp Biol Med (Maywood). 2018;243:96-106 pubmed publisher
    ..Sprague-Dawley rats were maintained either on tap water (controls) or on water solution of thioacetamide to produce liver cirrhosis (CRH-R)...
  9. Yang X, Zou W, Zeng J, Xie S, An T, Luo X, et al. Prevalence of antimicrobial resistance and integron gene cassettes in Escherichia coli isolated from yaks (Poephagus grunniens) in Aba Tibetan Autonomous Prefecture, China. Microb Pathog. 2017;111:274-279 pubmed publisher
    ..coli isolated from yaks in Aba Tibetan Autonomous Prefecture (Aba TAP), China...
  10. Contini M, Fabro A, Millen N, Benmelej A, Mahieu S. Adverse effects in kidney function, antioxidant systems and histopathology in rats receiving monosodium glutamate diet. Exp Toxicol Pathol. 2017;69:547-556 pubmed publisher
    ..35% NaCl solution permanently alone at the same frequency and time; 3) control group were fed the normal chow and tap water...
  11. Benhelima A, Kaid Omar Z, Hemida H, Benmahdi T, Addou A. NEPHROPROTECTIVE AND DIURETIC EFFECT OF NIGELLA SATIVA L SEEDS OIL ON LITHIASIC WISTAR RATS. Afr J Tradit Complement Altern Med. 2016;13:204-214 pubmed publisher
    ..Thirty male Wistar rats were divided into 5 groups (N=6). Group I, negative control, drank tap water...
  12. Morer C, Roques C, Francon A, Forestier R, Maraver F. The role of mineral elements and other chemical compounds used in balneology: data from double-blind randomized clinical trials. Int J Biometeorol. 2017;61:2159-2173 pubmed publisher
    ..double-blind randomized clinical trials that assessed the effects of mineral water or mud treatments compared to tap water, attenuated peloid/mud therapy or similar treatments without the specific minerals or chemical compounds of ..
  13. Abdel Daim M, Eissa I, Abdeen A, Abdel Latif H, Ismail M, Dawood M, et al. Lycopene and resveratrol ameliorate zinc oxide nanoparticles-induced oxidative stress in Nile tilapia, Oreochromis niloticus. Environ Toxicol Pharmacol. 2019;69:44-50 pubmed publisher
    ..Five groups with 20 fish each were used; Control, received tap water only; ZnONP group, was intoxicated with ZnONP (50 mg/L); ZnONP-LYC group, was exposed to ZnONP and LYC (500..
  14. Prince P, Santander Y, Geréz E, Hocht C, Polizio A, Mayer M, et al. Fructose increases corticosterone production in association with NADPH metabolism alterations in rat epididymal white adipose tissue. J Nutr Biochem. 2017;46:109-116 pubmed publisher
    ..Male Sprague-Dawley rats fed with a fructose solution (10% (w/v) in tap water) during 9 weeks developed some characteristic features of metabolic syndrome, such as hypertriglyceridemia, ..
  15. Kuo K, Wu B, Liu C, Yang T, Kao L, Wu J, et al. Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. J Lipid Res. 2015;56:2070-84 pubmed publisher
    ..KMUP-1 HCl in drinking water (2.5 mg/200 ml tap water) for 1-14 or 8-14 weeks decreased HFD-induced liver and body weight and scavenger receptor class B type I ..
  16. Sai Siva Ram A, Pratap Reddy K, Girish B, Supriya C, Sreenivasula Reddy P. Arsenic aggravated reproductive toxicity in male rats exposed to lead during the perinatal period. Toxicol Res (Camb). 2018;7:1191-1204 pubmed publisher
    ..The pregnant rats were allowed ad libitum access to tap water containing 819 mg of lead (Pb) per L or without Pb from conception until weaning...
  17. Maqbool F, Bahadar H, Niaz K, Baeeri M, Rahimifard M, Navaei Nigjeh M, et al. Effects of methyl mercury on the activity and gene expression of mouse Langerhans islets and glucose metabolism. Food Chem Toxicol. 2016;93:119-28 pubmed publisher
    ..MeHg was dissolved in tap water and administered at doses 2.5, 5 and 10 mg/kg/day, for 4 weeks...
  18. Senaphan K, Sangartit W, Pakdeechote P, Kukongviriyapan V, Pannangpetch P, Thawornchinsombut S, et al. Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet. Eur J Nutr. 2018;57:219-230 pubmed publisher
    ..Male Sprague-Dawley rats were fed either a standard chow and tap water or a HCHF diet and 15 % fructose solution for 16 weeks...
  19. Senaphan K, Kukongviriyapan U, Sangartit W, Pakdeechote P, Pannangpetch P, Prachaney P, et al. Ferulic Acid Alleviates Changes in a Rat Model of Metabolic Syndrome Induced by High-Carbohydrate, High-Fat Diet. Nutrients. 2015;7:6446-64 pubmed publisher
    ..diet and 15% fructose in drinking water for 16 weeks, where control rats were fed with standard chow diet and tap water...
  20. Bandh S, Kamili A, Ganai B, Lone B. Opportunistic fungi in lake water and fungal infections in associated human population in Dal Lake, Kashmir. Microb Pathog. 2016;93:105-10 pubmed publisher
    ..77%) was seen in people using lake water followed by a positive prevalence of 1.30% using tap water...
  21. Kang J, Kang D. The Synergistic Bactericidal Mechanism of Simultaneous Treatment with a 222-Nanometer Krypton-Chlorine Excilamp and a 254-Nanometer Low-Pressure Mercury Lamp. Appl Environ Microbiol. 2019;85: pubmed publisher
    ..i>enterica serovar Typhimurium, and Listeria monocytogenes in tap water and to identify the synergistic bactericidal mechanism...
  22. Kisku S, Sen S, Karl S, Mathai J, Thomas R, Barla R. Bladder calculi in the augmented bladder: a follow-up study of 160 children and adolescents. J Pediatr Urol. 2015;11:66.e1-6 pubmed publisher
    ..3 years) were followed up for a median of 70.5 months. All patients performed daily bladder irrigation with tap or drinking water. Post-operative bladder calculi were noted in 14 (8.8%) of 160 patients following BA...
  23. Zhou X, Kong D, Li J, Pang B, Zhao Y, Zhou J, et al. An Outbreak of Gastroenteritis Associated with GII.17 Norovirus-Contaminated Secondary Water Supply System in Wuhan, China, 2017. Food Environ Virol. 2019;: pubmed publisher
    ..Feces or anal swabs from individuals, water, and swabs taken from tap surfaces of the secondary water supply system (SWSS) and foods were collected for the detection of viruses and ..
  24. Inkielewicz Stępniak I. Impact of fluoxetine on liver damage in rats. Pharmacol Rep. 2011;63:441-7 pubmed
    ..Eighteen adult male Wistar rats were divided into three equal groups of six animals each: (I) controls who drank tap water and received 1 ml of tap water intragastrically; (II) animals that received 8 mg Flux/kg bw/day ..
  25. Rukavina Mikusic N, Kouyoumdzian N, Uceda A, Del Mauro J, Pandolfo M, Gironacci M, et al. Losartan prevents the imbalance between renal dopaminergic and renin angiotensin systems induced by fructose overload. l-Dopa/dopamine index as new potential biomarker of renal dysfunction. Metabolism. 2018;85:271-285 pubmed publisher
    ..rats were randomly divided into four groups and studied at 4, 8 and 12 weeks: control group (C4, C8 and C12; tap water to drink); fructose-overloaded group (F4, F8 and F12; 10% w/v fructose solution to drink); losartan-treated ..
  26. Sachdeva M, Moshiri A, Leder H, Scott A. Endophthalmitis following intravitreal injection of anti-VEGF agents: long-term outcomes and the identification of unusual micro-organisms. J Ophthalmic Inflamm Infect. 2016;6:2 pubmed publisher
    ..While all but one patient were treated with initial vitreous tap and intravitreal injection of antibiotics, both patients with these rare organisms exhibited persistent vitritis ..
  27. Boonloh K, Lee E, Kim H, Kwon M, Kim Y, Pannangpetch P, et al. Rice bran protein hydrolysates attenuate diabetic nephropathy in diabetic animal model. Eur J Nutr. 2018;57:761-772 pubmed publisher
    ..Eight-week-old male db/m and db/db mice were orally treated with tap water or RBP (100 or 500 mg/kg/day) for 8 weeks...
  28. Kellen D, Pachur T, Hertwig R. How (in)variant are subjective representations of described and experienced risk and rewards?. Cognition. 2016;157:126-138 pubmed publisher
    ..At the same time, both types of decisions seem to tap into the same individual-level regularities.
  29. Glorennec P, Lucas J, Mercat A, Roudot A, Le Bot B. Environmental and dietary exposure of young children to inorganic trace elements. Environ Int. 2016;97:28-36 pubmed publisher
    ..exposure of children aged 3-6years, living in France, to As, Cd, Cr, Cu, Mn, Pb, Sb, Sr, and V present in diet, tap water, air, soil and floor dust in the years 2007-2009...
  30. De Visscher A, Piepers S, Haesebrouck F, Supre K, De Vliegher S. Coagulase-negative Staphylococcus species in bulk milk: Prevalence, distribution, and associated subgroup- and species-specific risk factors. J Dairy Sci. 2017;100:629-642 pubmed publisher
    ..Always wearing gloves during milking decreased the odds of having Staphylococcus devriesei-positive bulk milk. Tap water from the public drinking system used as drinking water increased the odds of yielding S...
  31. Nagy N, Vanky F, Klein E. Tumor surveillance: expression of the transporter associated with antigen processing (TAP-1) in ex-vivo human tumor samples and its elevation by in vitro treatment with IFN-gamma and TNF-alpha. Immunol Lett. 1998;64:153-60 pubmed
    ..carcinomas and one malignant melanoma) for the expression of the transporter associated with antigen processing, TAP-1...
  32. Han S, Lee J, Kim C, Hong S. Identification of p115 as a PLCgamma1-binding protein and the role of Src homology domains of PLCgamma1 in the vesicular transport. Biochem Biophys Res Commun. 2003;300:649-55 pubmed
    ..Several immunoreactive clones were identified as the putative binding proteins and one of them was identified as p115. p115 was reported to be required for transcytotic fusion and subsequent binding of the vesicles to the target ..
  33. Onufrak S, Park S, Sharkey J, Merlo C, Dean W, Sherry B. Perceptions of tap water and school water fountains and association with intake of plain water and sugar-sweetened beverages. J Sch Health. 2014;84:195-204 pubmed publisher
    Little is known regarding youth perceptions of tap water and school water fountains and how these relate to water and sugar-sweetened beverage (SSB) intake...
  34. Oldham M, Grigorieff N, Chen J. Structure of the transporter associated with antigen processing trapped by herpes simplex virus. elife. 2016;5: pubmed publisher
    The transporter associated with antigen processing (TAP) is an ATP-binding cassette (ABC) transporter essential to cellular immunity against viral infection...
  35. Al Baldawi I. Removal of 1,2-Dichloroethane from real industrial wastewater using a sub-surface batch system with Typha angustifolia L. Ecotoxicol Environ Saf. 2018;147:260-265 pubmed publisher
    ..Three SSCWs (T2, T3 and T4) were fed with real wastewater, and another one (T1) was fed with tap water (as plant control) to assess the role of T. angustifolia L...
  36. Seve P, Cacoub P, Bodaghi B, Trad S, Sellam J, Bellocq D, et al. Uveitis: Diagnostic work-up. A literature review and recommendations from an expert committee. Autoimmun Rev. 2017;16:1254-1264 pubmed publisher
    ..release, chest computed tomography (chronic uveitis), cerebral magnetic resonance imaging and anterior chamber tap with interleukin-10 analysis (intermediate or posterior uveitis in patients >40years-old)...
  37. Yun J, Bhattarai S, Yun Y, Lee Y. Synthesis of thiourea-immobilized polystyrene nanoparticles and their sorption behavior with respect to silver ions in aqueous phase. J Hazard Mater. 2018;344:398-407 pubmed publisher
    ..The sorption performance did not significantly decrease in tap water containing competing ions...
  38. Lajoie J, Zijenah L, Faucher M, Ward B, Roger M. Novel TAP1 polymorphisms in indigenous Zimbabweans: their potential implications on TAP function and in human diseases. Hum Immunol. 2003;64:823-9 pubmed
    ..Thus, TAP1 polymorphism has evolved differently among populations presumably because of the evolutionary pressures generated by prevalent pathogens in these geographically distinct regions...
  39. Gomez L, Camargo J, Castiblanco J, Ruiz Narvaez E, Cadena J, Anaya J. Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis. Tissue Antigens. 2006;67:290-6 pubmed
    ..The transporter associated with antigen processing (TAP) is involved in the antigen processing via major histocompatibility complex class I molecules and in turn might ..
  40. Es haghi Z, Nezhadali A, Khatibi A. Magnetically responsive polycaprolactone nanoparticles for progesterone screening in biological and environmental samples using gas chromatography. Anal Bioanal Chem. 2016;408:5537-49 pubmed publisher
    ..GC-FID) for monitoring of progesterone (PGN) hormone in biological and environmental matrices, namely blood serum, tap water, urine, and hospital wastewater...
  41. Kaur M, Mehta S, Kansal S. A fluorescent probe based on nitrogen doped graphene quantum dots for turn off sensing of explosive and detrimental water pollutant, TNP in aqueous medium. Spectrochim Acta A Mol Biomol Spectrosc. 2017;180:37-43 pubmed publisher
    ..92?M. The presented method was successfully applied to the sensing of TNP in tap and lake water samples with satisfactory results...
  42. Stets E, Lee C, Lytle D, Schock M. Increasing chloride in rivers of the conterminous U.S. and linkages to potential corrosivity and lead action level exceedances in drinking water. Sci Total Environ. 2018;613-614:1498-1509 pubmed publisher
    ..is a costly problem and controlling corrosion is a primary focus of efforts to reduce lead (Pb) and copper (Cu) in tap water. High chloride concentrations can increase the tendency of water to cause corrosion in distribution systems...
  43. Jian J, Guo Y, Zeng L, Liang Ying L, Lu X, Wang F, et al. Global distribution of perfluorochemicals (PFCs) in potential human exposure source-A review. Environ Int. 2017;108:51-62 pubmed publisher
    ..Well water and tap water contained relatively higher PFC concentrations than other types of drinking water...
  44. You M, Rensing K, Renton M, Barbetti M. Modeling Effects of Temperature, Soil, Moisture, Nutrition and Variety As Determinants of Severity of Pythium Damping-Off and Root Disease in Subterranean Clover. Front Microbiol. 2017;8:2223 pubmed publisher
    ..high-level (4 or 5-way) significant interactions for each dependent variable (dry shoot and root weight, emergence, tap and lateral root disease index)...
  45. Tsory S, Kellman Pressman S, Fishman D, Segal S. Reconstitution of expression of H-2K region-encoded murine MHC class I glycoproteins in MHC class I-deficient B16BL6 melanoma cells affects the expression and function of antigen-processing machinery. Immunol Lett. 2006;102:237-40 pubmed
    ..evidence that re-expression of an H-2K MHC class I-encoding gene in these cells also augments the expression of the Tap-2 peptide transporter and the inducible proteasome subunits, i.e. Lmp-2, Lmp-7 and Lmp-10...
  46. Coryell M, Wunsch A, Haenfler J, Allen J, Schnizler M, Ziemann A, et al. Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior. J Neurosci. 2009;29:5381-8 pubmed publisher
    ..However, a number of behavioral tests in rodents are sensitive to antidepressants and may thus tap important underlying biological factors...
  47. BitiktaÅŸ S, Tan B, Batakçı M, Kavraal Å, Dursun N, Süer C. Effects of selenium treatment on 6-n-propyl-2-thiouracil-induced impairment of long-term potentiation. Neurosci Res. 2016;109:70-6 pubmed publisher
    ..Hypothyroidism was induced in young-adult rats by the administration of 6-n-propyl-2-thiouracil (PTU) in tap water for 21 days. Half of these hypothyroid and euthroid rats were given 10ppM selenium with their drinking water...
  48. Avanasi R, Shin H, VIEIRA V, Bartell S. Impacts of geocoding uncertainty on reconstructed PFOA exposures and their epidemiological association with preeclampsia. Environ Res. 2016;151:505-512 pubmed publisher
    ..exposure mischaracterization can be reduced by obtaining accurate exposure information such as street addresses and tap water consumption, for both workplaces and residences...
  49. Lee N, Jung H, Ok G, Lee S. Acute effects of Kinesio taping on muscle function and self-perceived fatigue level in healthy adults. Eur J Sport Sci. 2017;17:757-764 pubmed publisher
    ..82?±?3.71 years]) were enrolled in this study. All subjects underwent three different trials which included no tap (NT), placebo tap (PT), and KT...
  50. Ottem E, Bailey D, Jordan C, Breedlove S. With a little help from my friends: androgens tap BDNF signaling pathways to alter neural circuits. Neuroscience. 2013;239:124-38 pubmed publisher
    ..Finally, we provide hypothetical models of mechanisms that may underlie androgen- and BDNF-dependent signaling pathways. ..
  51. Kohli M, Yamaguchi M, Setzer F, Karabucak B. Spectrophotometric Analysis of Coronal Tooth Discoloration Induced by Various Bioceramic Cements and Other Endodontic Materials. J Endod. 2015;41:1862-6 pubmed publisher
    ..France); WMTA, white MTA (Dentsply, York, PA), GMTA, gray MTA (Dentsply); AH+, AH Plus sealer (Dentsply); TAP, triple antibiotic paste (metronidazole, ciprofloxacin, and minocycline); and NF, no filling (negative control ..
  52. Thomen R, Walkup L, Roach D, Cleveland Z, Clancy J, Woods J. Hyperpolarized 129Xe for investigation of mild cystic fibrosis lung disease in pediatric patients. J Cyst Fibros. 2017;16:275-282 pubmed publisher
    ..Each subject was imaged via hyperpolarized 129Xe MRI, and the ventilation defect percentage (VDP) was measured. FEV1 and VDP were compared between the groups. FEV1 for controls was 100.3%±8...
  53. Pinho D, Lev Cohain N, Awdeh H, Xi Y, Khatri G, Yokoo T, et al. Optimization of breathing instructions and timing of late arterial phase acquisition on gadobutrol-enhanced MRI of the liver. Clin Imaging. 2016;40:1274-1279 pubmed publisher
    ..were quantitatively evaluated for image quality (IQ), breathing artifacts (BA), and timing of the arterial phase (Tap). Quantitative analysis was also performed. No significant differences in IQ, BA and Tap (P>.05)...
  54. Taghdisi S, Danesh N, Ramezani M, Ghows N, Mousavi Shaegh S, Abnous K. A novel fluorescent aptasensor for ultrasensitive detection of microcystin-LR based on single-walled carbon nanotubes and dapoxyl. Talanta. 2017;166:187-192 pubmed publisher
    ..This new method indicated excellent analytical performance for MC-LR detection in tap water and serum samples with LODs of 135 and 168 pM, respectively.
  55. Saxon D, Ashley K, Bishop Edwards L, Connell J, Harrison P, Ohlsen S, et al. A pragmatic randomised controlled trial assessing the non-inferiority of counselling for depression versus cognitive-behaviour therapy for patients in primary care meeting a diagnosis of moderate or severe depression (PRaCTICED): Study protocol for a. Trials. 2017;18:93 pubmed publisher
    ..Secondary outcome measures tap depression, generic psychological distress, anxiety, functioning and quality of life...
  56. Parvez S, Frost K, Sundararajan M. Evaluation of Drinking Water Disinfectant Byproducts Compliance Data as an Indirect Measure for Short-Term Exposure in Humans. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..Short-term residential tap water samples were collected in peak DBP months (May-August) in a community water system with five separate ..
  57. Kimura T, Hashimoto I, Nagase T, Fujisawa J. CRM1-dependent, but not ARE-mediated, nuclear export of IFN-alpha1 mRNA. J Cell Sci. 2004;117:2259-70 pubmed
    While the bulk of cellular mRNA is known to be exported by the TAP pathway, export of specific subsets of cellular mRNAs may rely on chromosome region maintenance 1 (CRM1)...
  58. Kodamatani H, Iwaya Y, Saga M, Saito K, Fujioka T, Yamazaki S, et al. Ultra-sensitive HPLC-photochemical reaction-luminol chemiluminescence method for the measurement of secondary amines after nitrosation. Anal Chim Acta. 2017;952:50-58 pubmed publisher
    ..We then applied this method for the detection and quantification of these secondary amines in samples of tap water, river water, treated wastewater, and sea water. Dimethylamine was detected at concentrations up to 15...
  59. Kang H, Shin G. Effects of touch target location on performance and physical demands of computer touchscreen use. Appl Ergon. 2017;61:159-167 pubmed publisher
    ..The objective of this study was to evaluate how physical demands and task performance of a tap gesture on a computer touchscreen vary between target locations and display positions...
  60. Ohashi Y, Shiba E, Yamashita H, Kurebayashi J, Noguchi S, Iwase H, et al. Comparison of quality of life between 2-year and 3-or-more-year administration of leuprorelin acetate every-3-months depot in combination with tamoxifen as adjuvant endocrine treatment in premenopausal patients with endocrine-responsive breast cancer. Support Care Cancer. 2018;26:933-945 pubmed publisher
    ..randomized controlled trial evaluating the appropriate treatment duration of leuprorelin acetate 3-month depot, TAP-144-SR (3M), administered postsurgically every 3 months for 2 years versus 3 or more (up to 5) years, in ..
  61. Oliveira M, Nascimento Gonçalves E, Silva J, Oliveira P, Ferreira R, Antunes L, et al. Implementation of Humane Endpoints in a Urinary Bladder Carcinogenesis Study in Rats. In Vivo. 2017;31:1073-1080 pubmed
    ..The control group (n=9) received tap water while the test group (n=12) received the carcinogen N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) in drinking ..
  62. Leng T, Moshfeghi D. Valved 25-Gauge Cannula for Vitreous Tap and Injection. Ophthalmic Surg Lasers Imaging Retina. 2017;48:916-917 pubmed publisher
    To describe a technique that reduces patient discomfort by using a valved 25-gauge trocar for vitreous tap and intravitreal injection of medications in previously vitrectomized eyes with suspected infectious endophthalmitis...
  63. Mendoza A, Zonja B, Mastroianni N, Negreira N, López de Alda M, Pérez S, et al. Drugs of abuse, cytostatic drugs and iodinated contrast media in tap water from the Madrid region (central Spain):A case study to analyse their occurrence and human health risk characterization. Environ Int. 2016;86:107-18 pubmed publisher
    ..twenty-five drugs of abuse and metabolites, seventeen cytostatic drugs and six iodinated contrast media, in tap water from the Madrid Region...
  64. Park S, Park J, Choi G, Kim H, Moon S, Yeo J. Comparison of Analgesic Efficacy of Laparoscope-Assisted and Ultrasound-Guided Transversus Abdominis Plane Block after Laparoscopic Colorectal Operation: A Randomized, Single-Blind, Non-Inferiority Trial. J Am Coll Surg. 2017;225:403-410 pubmed publisher
    Transversus abdominis plane (TAP) block has been used as a component of multimodal analgesia after abdominal operation...
  65. Türkaydın D, Demir E, Basturk F, Sazak Oveçoğlu H. Efficacy of XP-Endo Finisher in the Removal of Triple Antibiotic Paste from Immature Root Canals. J Endod. 2017;43:1528-1531 pubmed publisher
    ..with passive ultrasonic irrigation (PUI) and needle irrigation in the removal of triple antibiotic paste (TAP) from the straight immature root canals of extracted teeth...
  66. Yu T, Hwang J, Aurbach D, Sun Y. A microsphere Na0.65[Ni0.17Co0.11Mn0.72]O2 Cathode material for High Performance Sodium-Ion Batteries. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    ..Simultaneously, the hierarchical microstructure enhances the structural stability and high tap density (~1.18 g cm-3). Benefiting from these merits, the proposed P2-type micro-sphere Na0.65[Ni0.17Co0.11Mn0...
  67. Paulsson K. Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery. Cell Mol Life Sci. 2004;61:2446-60 pubmed
    ..are transported into the lumen of the endoplasmic reticulum by transporters associated with antigen processing (TAP)...
  68. Kuchtey J, Chefalo P, Gray R, Ramachandra L, Harding C. Enhancement of dendritic cell antigen cross-presentation by CpG DNA involves type I IFN and stabilization of class I MHC mRNA. J Immunol. 2005;175:2244-51 pubmed
    ..This processing can occur by transporter for Ag presentation (TAP)-dependent or TAP-independent mechanisms...
  69. Lin H, Su B, Hsu C, Chou I, Wu K, Lin H, et al. No association between TAP1 DpnII polymorphism and bronchopulmonary dysplasia. Acta Paediatr Taiwan. 2005;46:341-5 pubmed
    ..To test whether TAP polymorphism has a role in the BPD, we investigated the association between TAP1 polymorphism and BPD by analyzing ..
  70. Einstein M, Leanza S, Chiu L, Schlecht N, Goldberg G, Steinberg B, et al. Genetic variants in TAP are associated with high-grade cervical neoplasia. Clin Cancer Res. 2009;15:1019-23 pubmed publisher
    The transporter associated with antigen processing (TAP) is essential in assembling MHC-I proteins...
  71. Bomberger J, Ely K, Bangia N, Ye S, Green K, Green W, et al. Pseudomonas aeruginosa Cif protein enhances the ubiquitination and proteasomal degradation of the transporter associated with antigen processing (TAP) and reduces major histocompatibility complex (MHC) class I antigen presentation. J Biol Chem. 2014;289:152-62 pubmed publisher
    ..Cif is the first bacterial factor identified that inhibits TAP function and MHC class I antigen presentation.
  72. Bjerre Harpøth V, Storm A, Eslamizad M, Kuhla B, Larsen M. Effect of propylene glycol on adipose tissue mobilization in postpartum over-conditioned Holstein cows. J Dairy Sci. 2015;98:8581-96 pubmed publisher
    ..and arterially catheterized cows were, at parturition, randomly assigned to a ruminal pulse dose of either 500g of tap water (n=4) or 500g of PG (n=5) once a day...
  73. Bégel V, Benoit C, Correa A, Cutanda D, Kotz S, Dalla Bella S. "Lost in time" but still moving to the beat. Neuropsychologia. 2017;94:129-138 pubmed publisher
    ..Yet, they could tap to the beat of the same stimuli. L.V. showed impairments in both beat perception and tapping...
  74. Zha W, Kruger S, Cadman R, Mummy D, Evans M, Nagle S, et al. Regional Heterogeneity of Lobar Ventilation in Asthma Using Hyperpolarized Helium-3 MRI. Acad Radiol. 2018;25:169-178 pubmed publisher
    ..We classified the gas volume into four signal intensity levels as follows: ventilation defect percent (VDP), low ventilation percent, medium ventilation percent, and high ventilation percent...
  75. Keicho N, Tokunaga K, Nakata K, Taguchi Y, Azuma A, Tanabe K, et al. Contribution of TAP genes to genetic predisposition for diffuse panbronchiolitis. Tissue Antigens. 1999;53:366-73 pubmed
    ..Besides the class I gene itself, genes relevant to the class I antigen presenting system might contribute to its genetic predisposition...
  76. How P, Shields D. Tethering function of the caspase cleavage fragment of Golgi protein p115 promotes apoptosis via a p53-dependent pathway. J Biol Chem. 2011;286:8565-76 pubmed publisher
    ..Significantly, the Golgi-vesicle-tethering protein p115 is cleaved at Asp(757) early during apoptosis and the nuclear translocation of its 205 amino acid C-terminal ..
  77. Schumacher T, Kantesaria D, Heemels M, Ashton Rickardt P, Shepherd J, Fruh K, et al. Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. J Exp Med. 1994;179:533-40 pubmed
    The transporter associated with antigen processing (TAP) delivers peptides to the lumen of the endoplasmic reticulum in an adenosine triphosphate (ATP) dependent fashion for presentation by major histocompatibility complex class I ..
  78. Matamoros N, Mila J, Llano M, Balas A, Vicario J, Pons J, et al. Molecular studies and NK cell function of a new case of TAP2 homozygous human deficiency. Clin Exp Immunol. 2001;125:274-82 pubmed
    ..Expression of HLA-E was virtually undetectable in GOR B-LCL and very faint in PBMC, further supporting that interactions of class I leader sequence nonamers with HLA-E in the ER depend on a functional TAP complex.
  79. Campbell J, Biggin P, Baaden M, Sansom M. Extending the structure of an ABC transporter to atomic resolution: modeling and simulation studies of MsbA. Biochemistry. 2003;42:3666-73 pubmed
    ..MsbA is of some biomedical interest as it is homologous to mammalian transporters such as P-glycoprotein and TAP. The quality of the MsbA model is assessed using a combination of molecular dynamics simulations and static ..
  80. Xie J, Hu Y, Lu Y, Li Z, Gong W, Yu S, et al. [Expression of transporter associated with antigen processing (TAP) in childhood acute leukemia and its clinical significance]. Ai Zheng. 2003;22:1062-5 pubmed
    Transporter associated with antigen processing(TAP) participates in immune surveillance, so it is probably relevant to carcinogenesis...
  81. Wolters J, Abele R, Tampe R. Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9). J Biol Chem. 2005;280:23631-6 pubmed
    The transporter associated with antigen processing (TAP)-like (TAPL, ABCB9) belongs to the ATP-binding cassette transporter family, which translocates a vast variety of solutes across membranes...
  82. Keusekotten K, Leonhardt R, Ehses S, Knittler M. Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2. J Biol Chem. 2006;281:17545-51 pubmed
    The transporter associated with antigen processing (TAP) is essential for the delivery of antigenic peptides from the cytosol into the endoplasmic reticulum (ER), where they are loaded onto major histocompatibility complex class I ..
  83. Soundravally R, Hoti S. Polymorphisms of the TAP 1 and 2 gene may influence clinical outcome of primary dengue viral infection. Scand J Immunol. 2008;67:618-25 pubmed publisher
    ..are actively transported across the endoplasmic reticulum by the transporters associated with antigen presentation (TAP)...
  84. Ortmann B, Copeman J, Lehner P, Sadasivan B, Herberg J, Grandea A, et al. A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. Science. 1997;277:1306-9 pubmed
    ..the endoplasmic reticulum chaperone calreticulin, interact with the transporter associated with antigen processing (TAP) through a molecule called tapasin...
  85. Stewart C, Laugier Anfossi F, Vely F, Saulquin X, Riedmuller J, Tisserant A, et al. Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc Natl Acad Sci U S A. 2005;102:13224-9 pubmed
    ..class I complexes on Epstein-Barr virus-infected cells in a transporter associated with antigen processing (TAP)-dependent manner...
  86. Leonhardt R, Abrahimi P, Mitchell S, Cresswell P. Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization. J Immunol. 2014;192:2480-94 pubmed publisher
    The TAP translocates peptide Ags into the lumen of the endoplasmic reticulum for loading onto MHC class I molecules...
  87. Kim H, Lee H, Lew B, Sim W, Kim Y, Lee S, et al. Association between TAP1 gene polymorphisms and alopecia areata in a Korean population. Genet Mol Res. 2015;14:18820-7 pubmed publisher
    The transporter 1 ATP-binding cassette sub-family B (MDR/TAP) gene (TAP1) is located in the major histocompatibility complex class II region, and forms a heterodimer that plays a key role in endogenous antigen presentation pathways...
  88. Tipple B, Jameel Y, Chau T, Mancuso C, Bowen G, Dufour A, et al. Stable hydrogen and oxygen isotopes of tap water reveal structure of the San Francisco Bay Area's water system and adjustments during a major drought. Water Res. 2017;119:212-224 pubmed publisher
    ..of these relationships within a megalopolis in the Western United States, we collected and analyzed 723 tap waters across the San Francisco Bay Area during seven collection campaigns spanning 21 months during 2013-2015...
  89. Tommasino L, Chen J, Falcomer R, Janik M, Kanda R, Defelice F, et al. AN INTERNATIONAL COOPERATION BY USING AN ALL-ENCOMPASSING PASSIVE RADON MONITOR. Radiat Prot Dosimetry. 2017;:1-4 pubmed publisher
    ..has been carried out by Health Canada in which radon in water was measured from 12 private wells, as well as in tap water originating from the Ottawa River...
  90. Tsai H, Yoshida T, Chuang T, Yang S, Chang C, Yao H, et al. Transversus Abdominis Plane Block: An Updated Review of Anatomy and Techniques. Biomed Res Int. 2017;2017:8284363 pubmed publisher
    Transversus abdominis plane (TAP) block is a regional technique for analgesia of the anterolateral abdominal wall...
  91. Ehses S, Leonhardt R, Hansen G, Knittler M. Functional role of C-terminal sequence elements in the transporter associated with antigen processing. J Immunol. 2005;174:328-39 pubmed
    b>TAP delivers antigenic peptides into the endoplasmic reticulum (ER) that are subsequently bound by MHC class I molecules. TAP consists of two subunits (TAP1 and TAP2), each with a transmembrane (TMD) and a nucleotide-binding (NBD) domain...
  92. Dugan G, Hewitt E. Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6. J Virol. 2008;82:3271-82 pubmed publisher
    The human cytomegalovirus (HCMV) protein US6 inhibits the transporter associated with antigen processing (TAP)...