Research Topics

Genomes and Genes



Gene Symbol: ORF7
Description: tegument protein UL51
Species: Human herpesvirus 3

Top Publications

  1. Jiang H, Wang W, Jiang X, Zeng W, Shen Z, Song Y, et al. ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells. J Virol. 2017;91: pubmed publisher
    ..Open reading frame 7 (ORF7) of VZV has been recognized as a neurotropic gene in vivo, but its neurovirulent role remains unclear...
  2. Zhang Z, Selariu A, Warden C, Huang G, Huang Y, Zaccheus O, et al. Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PLoS Pathog. 2010;6:e1000971 pubmed publisher
    ..One of the genes (ORF7) has never been described as a skin tropic factor...
  3. Selariu A, Cheng T, Tang Q, Silver B, Yang L, Liu C, et al. ORF7 of varicella-zoster virus is a neurotropic factor. J Virol. 2012;86:8614-24 pubmed publisher
    ..Here, screening of dispensable gene deletion mutants in differentiated neuronal cells led to the identification of ORF7 as the first known, likely a main, VZV neurotropic factor...