Gene Symbol: ORF23
Description: located externally on capsid hexons
Alias: located externally on capsid hexons, small capsid protein
Species: Human herpesvirus 3

Top Publications

  1. Chaudhuri V, Sommer M, Rajamani J, Zerboni L, Arvin A. Functions of Varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infection. J Virol. 2008;82:10231-46 pubmed publisher
    ..Based on comparative genome analyses, varicella-zoster virus (VZV) open reading frame 23 (ORF23) encodes a conserved capsid protein, referred to as VP26 (UL35) in other alphaherpesviruses...
  2. Reichelt M, Wang L, Sommer M, Perrino J, Nour A, Sen N, et al. Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. PLoS Pathog. 2011;7:e1001266 pubmed publisher
    ..PML IV significantly inhibited viral infection and interacted with the ORF23 capsid surface protein, which was identified as a target for PML-mediated NC sequestration...