OPN1LW

Summary

Gene Symbol: OPN1LW
Description: opsin 1 (cone pigments), long-wave-sensitive
Alias: CBBM, CBP, COD5, RCP, ROP, cone dystrophy 5 (X-linked), long-wave-sensitive opsin 1, red cone photoreceptor pigment, red-sensitive opsin
Species: human

Top Publications

  1. ncbi Expression of cAMP response element binding protein-binding protein in the song control system and hypothalamus of adult European starlings (Sturnus vulgaris)
    C J Auger
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore MD 21218 2686, USA
    J Neuroendocrinol 14:805-13. 2002
  2. doi Comparison of chain- and plate-loaded bench press training on strength, joint pain, and muscle soreness in Division II baseball players
    Kevin McCurdy
    Department of Health Physical Education and Recreation, Texas State University, San Marcos, Texas, USA
    J Strength Cond Res 23:187-95. 2009
  3. pmc Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors
    Guillermo Gerona-Navarro
    Department of Structural and Chemical Biology, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, New York 10029, United States
    J Am Chem Soc 133:2040-3. 2011
  4. pmc LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
    Katherine A Fitzgerald
    Division of Infectious Disease and Immunology, Department of Medicine, The University of Massachusetts Medical School, Worcester, MA 01605, USA
    J Exp Med 198:1043-55. 2003
  5. pmc Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
    K Ito
    Thoracic Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    Mol Cell Biol 20:6891-903. 2000
  6. ncbi Protein coregulators that mediate estrogen receptor function
    T Ratajczak
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Reprod Fertil Dev 13:221-9. 2001
  7. ncbi Against women: are we looking after our general practitioners? GPs' views of the 1990 part-time contract
    J Littlewood
    South Bank University, London
    J R Soc Promot Health 119:85-8. 1999
  8. ncbi 1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts
    Sungtae Kim
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706, USA
    J Bone Miner Res 20:305-17. 2005
  9. ncbi Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells
    D Sharma
    Department of Physiology, University of Maryland School of Medicine, Baltimore 21201, USA
    Mol Endocrinol 14:2001-9. 2000
  10. ncbi Treatment of hypertensive patients according to the conventional or ambulatory pressure: a progress report on the APTH trial. APTH Investigators. Ambulatory Blood Pressure and Treatment of Hypertension
    L Bieniaszewski
    Klinisch Laboratorium Hypertensie, Inwendige Geneeskunde Cardiologie U Z Gasthuisberg
    Acta Cardiol 51:243-51. 1996

Detail Information

Publications158 found, 100 shown here

  1. ncbi Expression of cAMP response element binding protein-binding protein in the song control system and hypothalamus of adult European starlings (Sturnus vulgaris)
    C J Auger
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore MD 21218 2686, USA
    J Neuroendocrinol 14:805-13. 2002
    ..The coactivator, cAMP response element binding protein (CREB)-binding protein (CBP), has been implicated in both androgen and oestrogen receptor transactivation...
  2. doi Comparison of chain- and plate-loaded bench press training on strength, joint pain, and muscle soreness in Division II baseball players
    Kevin McCurdy
    Department of Health Physical Education and Recreation, Texas State University, San Marcos, Texas, USA
    J Strength Cond Res 23:187-95. 2009
    The purpose of this study was to investigate the effects of chain- (CBP) and plate-loaded (PBP) bench press training on measures of strength, shoulder pain, and muscle soreness in Division II baseball players...
  3. pmc Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors
    Guillermo Gerona-Navarro
    Department of Structural and Chemical Biology, Mount Sinai School of Medicine, 1425 Madison Avenue, Box 1677, New York, New York 10029, United States
    J Am Chem Soc 133:2040-3. 2011
    The CREB binding protein (CBP) is a human transcriptional coactivator consisting of several conserved functional modules, which interacts with distinct transcription factors including nuclear receptors, CREB, and STAT proteins...
  4. pmc LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
    Katherine A Fitzgerald
    Division of Infectious Disease and Immunology, Department of Medicine, The University of Massachusetts Medical School, Worcester, MA 01605, USA
    J Exp Med 198:1043-55. 2003
    ..These studies suggest that TRIF and TRAM both function in LPS-TLR4 signaling to regulate the MyD88-independent pathway during the innate immune response to LPS...
  5. pmc Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
    K Ito
    Thoracic Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    Mol Cell Biol 20:6891-903. 2000
    ..Furthermore, we show that GR acts both as a direct inhibitor of CREB binding protein (CBP)-associated HAT activity and also by recruiting HDAC2 to the p65-CBP HAT complex...
  6. ncbi Protein coregulators that mediate estrogen receptor function
    T Ratajczak
    Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Reprod Fertil Dev 13:221-9. 2001
    ..of selected members of the multifunctional steroid receptor coactivator family and the cointegrators, p300/CBP and P/CAF...
  7. ncbi Against women: are we looking after our general practitioners? GPs' views of the 1990 part-time contract
    J Littlewood
    South Bank University, London
    J R Soc Promot Health 119:85-8. 1999
    ..This particularly affects women General Practitioners. Whilst the RCP policy statement addresses education and training for general practice, the question of not losing out in relation ..
  8. ncbi 1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts
    Sungtae Kim
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706, USA
    J Bone Miner Res 20:305-17. 2005
    ....
  9. ncbi Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells
    D Sharma
    Department of Physiology, University of Maryland School of Medicine, Baltimore 21201, USA
    Mol Endocrinol 14:2001-9. 2000
    ..Coactivators implicated in ligand-dependent activation by TR include p300, the CREB-binding protein (CBP), members of the p160/SRC family, and the multisubunit TR-associated protein (TRAP) complex...
  10. ncbi Treatment of hypertensive patients according to the conventional or ambulatory pressure: a progress report on the APTH trial. APTH Investigators. Ambulatory Blood Pressure and Treatment of Hypertension
    L Bieniaszewski
    Klinisch Laboratorium Hypertensie, Inwendige Geneeskunde Cardiologie U Z Gasthuisberg
    Acta Cardiol 51:243-51. 1996
    ..sitting diastolic pressure from 80 through 89 mm Hg on conventional sphygmomanometry (conventional blood pressure [CBP] group), and one in which a daytime (from 10 to 20 h) diastolic pressure from 80 through 89 mm Hg had to be ..
  11. doi Empiric antibiotics are justified for infants with respiratory syncytial virus lower respiratory tract infection presenting with respiratory failure: a prospective study and evidence review
    Daniel Levin
    Department of Pediatrics, Children s Hospital at Dartmouth, Dartmouth Medical School, Lebanon, NH, USA
    Pediatr Crit Care Med 11:390-5. 2010
    ..We hypothesized the composite diagnosis of concomitant bacterial pneumonia (CBP) is common in lower risk infants with RSV who present in respiratory failure...
  12. ncbi [Effect of continuous blood purification and thymosin alpha1 on the cellular immunity in patients with severe sepsis: a prospective, randomized, controlled clinical trial]
    Yi Nan Li
    Intensive Care Unit, the First Hospital of Foshan, Foshan 528000, Guangdong, China
    Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 21:139-42. 2009
    To discuss the effect of continuous blood purification (CBP), thymosin alpha1 and combined therapy on cellular immunity in patients with severe sepsis.
  13. ncbi In vivo complex formation of PU.1 with HDAC1 associated with PU.1-mediated transcriptional repression
    F Kihara-Negishi
    Department of Cell Genetics, Sasaki Institute, 2 2, Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    Oncogene 20:6039-47. 2001
    ..It was unlikely that the repression was due to sequestration of a limited amount of CBP/p300 nor pCAF, because overexpression of these co-activators did not relieve PU...
  14. ncbi Home blood pressure normalcy: the Didima study
    G S Stergiou
    Hypertension Center, Third University Department of Medicine, Sotiria Hospital, Athens, Greece
    Am J Hypertens 13:678-85. 2000
    ..4%). Clinic blood pressure (CBP) was measured on two visits (triplicate measurements, mercury sphygmomanometer) and HBP on 3 workdays (duplicate ..
  15. ncbi Protective effect of Weikang decoction and partial ingredients on model rat with gastric mucosa ulcer
    Tuo Ying Fan
    Shenzhen Donghu Hospital, Shenzhen 518020, Guangdong Province, China
    World J Gastroenterol 11:1204-9. 2005
    ..To investigate the protective mechanisms of Weikang (WK) decoction on gastric mucosae...
  16. ncbi Gene amplification and expression of the steroid receptor coactivator SRC3 (AIB1) in sporadic breast and endometrial carcinomas
    M Glaeser
    Department of Gynecology and Obstetrics, Heinrich-Heine-University, Duesseldorf, Germany
    Horm Metab Res 33:121-6. 2001
    ..It binds to nuclear receptors in a ligand-dependent fashion and recruits other factors such as CBP and p300 to the transactivation complex...
  17. ncbi [Determining factors in decisions regarding cardio-pulmonary resuscitation in patients with cerebral hemorrhage]
    J R Ara
    , Hospital Miguel Servet, Zaragoza,
    Rev Neurol 25:1518-20. 1997
    ..RESULTS: We identified 73 patients, 50 men and 23 women. Their mean age was 61 years. RCP was performed in 25 patients (34%). A logistic regression revealed that age (OR 0...
  18. ncbi Stability of YACs containing ribosomal or RCP/GCP locus DNA in wild-type S. cerevisiae and RAD mutant strains
    K Kohno
    Department of Molecular and Cellular Biology for Pharmaceutical Sciences, Kyoto Pharmaceutical University, Japan
    DNA Res 1:191-9. 1994
    ....
  19. ncbi Rubinstein-Taybi syndrome with epidermal nevus: a case report
    C Schepis
    Unit of Dermatology and Department of Pediatrics, Oasi Institute (IRCCS, Troina, Italy
    Pediatr Dermatol 18:34-7. 2001
    ..facies, and mental retardation caused by mutations in the transcriptional coactivator CREB binding protein (CBP)...
  20. ncbi [Correlation between XRCC2 and XRCC5 single nucleotide polymorphisms and drug-sensitivity of human lung cancer cells]
    Rui Wang
    Department of Thoracic Surgery, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang 050011, China
    Zhonghua Yi Xue Za Zhi 88:3059-62. 2008
    ..To study the associations between XRCC2 and XRCC5 single nucleotide polymorphisms (SNPs) and chemosensitivity of human lung cancer cells...
  21. doi Corn expressing an Escherichia coli-derived phytase gene: comparative evaluation study in broiler chicks
    E K D Nyannor
    Department of Animal Science, Purdue University, West Lafayette, IN 47907 2054, USA
    Poult Sci 87:2015-22. 2008
    The efficacy of corn expressing an Escherichia coli-derived gene (corn-based phytase; CBP) and an E...
  22. ncbi The international atom: evolution of radiation control programs
    F J Bradley
    Health Phys 83:121-34. 2002
    ..pool reactor in 1962 that initiated a health physics program for the reactor and a Radiation Control Program (RCP) for the country's use of ionizing radiation...
  23. ncbi Transactivation mechanisms of mouse clock transcription factors, mClock and mArnt3
    S Takahata
    Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan
    Genes Cells 5:739-47. 2000
    ..Yeast and mammalian two-hybrid systems revealed that CBP and p300 interacted with mArnt3 via the CREB binding domain...
  24. ncbi Clinical analysis of 43 cases of chronic benzene poisoning
    Shouren Kuang
    Guangdong Poison Control Center, 165 Xin gang Road, Guangzhou 510300, PR China
    Chem Biol Interact 153:129-35. 2005
    Benzene can result in bone marrow suppression. Chronic benzene poisoning (CBP) can be found among workers with excessive benzene exposure...
  25. ncbi In-house preparation of technetium 99m-labeled human serum albumin for evaluation of protein-losing gastroenteropathy
    Joseph C Hung
    Nuclear Pharmacy Laboratories and PET Radiochemistry Facility, Department of Radiology, Mayo Clinic, Rochester, Minn 55905 0001, USA
    J Am Pharm Assoc (Wash) 42:57-62. 2002
    ..To develop an in-house preparation method for technetium 99m-labeled human serum albumin (99mTc-HSA) to meet the clinical need for gastrointestinal (GI) protein loss evaluation in our institution...
  26. ncbi Characterisation of cellulose-binding proteins that are involved in the adhesion mechanism of Fibrobacter intestinalis DR7
    J Miron
    Metabolic Unit, Volcani Center, Bet Dagan, Israel
    Appl Microbiol Biotechnol 51:491-7. 1999
    Cellulose-binding proteins (CBP) isolated from cell envelopes of the cellulolytic bacterium Fibrobacter intestinalis strain DR7 were studied in order to investigate the adhesion mechanism...
  27. pmc SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment
    Ryan D Mohan
    Department of Physiology and Pharmacology, Siebens Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6G 2V4
    Mol Cell Biol 27:229-43. 2007
    ..enzyme thymine DNA glycosylase (TDG) mediates recruitment of histone acetyltransferases CREB-binding protein (CBP) and p300 to DNA, suggesting a plausible role for these factors in TDG-mediated repair...
  28. ncbi Rab coupling protein (RCP): a novel target of progesterone action in primate endometrium
    V S Patil
    Primate Biology Department, National Institute for Research in Reproductive Health, Indian Council of Medical Research, Parel, Mumbai 400 012, India
    J Mol Endocrinol 35:357-72. 2005
    ..DD2 sequence was found to be homologous to the sequence of the carboxyl terminal region of Rab coupling protein (RCP), a recently discovered protein involved in intracellular vesicular trafficking...
  29. ncbi Occlusal changes following posterior tooth loss in adults. Part 3. A study of clinical parameters associated with the presence of occlusal interferences following posterior tooth loss
    Helen L Craddock
    Restorative Dentistry, Leeds Dental Institute, Clarendon Way, Leeds, UK
    J Prosthodont 17:25-30. 2008
    ..The purpose of this study was to determine clinical parameters associated with the presence of retruded contact position (RCP) contacts and occlusal interferences associated with posterior tooth loss.
  30. ncbi Analysis of occlusal contacts in different types of prosthodontic appliances, Eichner classifications, presence RCP-ICP slide and the type of occlusion
    J Stipetić
    Department of Prosthodontic, School of Dental Medicine, University of Zagreb, Croatia
    Coll Antropol 25:311-6. 2001
    ..weak) with respect to the type of occlusion (canine guided, group function or balanced) and the presence of the RCP-ICP slide...
  31. ncbi Properties of cattle bone powder-coated composite particles as high-performance and open column liquid chromatographic column packings
    F Honda
    PHD Inc, Hokkaido, Japan
    J Chromatogr A 813:21-33. 1998
    Cattle bone powder (CBP) from natural resources was employed as a protein adsorbent instead of chemically synthesized hydroxyapatite (HA). Though a small amount of impurities was detected, CBP possessed a crystallinity similar to HA...
  32. ncbi Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.)
    Karolien P B Van den Bergh
    Laboratory of Phytopathology and Plant Protection, Katholieke Universiteit Leuven, Willem de Croylaan 42, 3001 Leuven, Belgium
    Planta 219:221-32. 2004
    ..Both the small hevein-like chitin-binding protein (Ee-CBP) and the classical class-I chitinase (Ee-chitinase) possess antifungal properties, Ee-CBP being far more potent ..
  33. ncbi [Penetrability of amikacin into prostate tissues in rat models of chronic bacterial prostatitis]
    He Wang
    Department of Microbiology, Guiyang Medical College, Guiyang, Guizhou 550004, China
    Zhonghua Nan Ke Xue 14:583-9. 2008
    ..To establish the rat model of chronic bacterial prostatitis and investigate the penetrability of amikacin to chronic inflammatory prostatic tissues...
  34. ncbi Cell separation based on the reversible interaction between calmodulin and a calmodulin-binding peptide
    R J Colinas
    The Wadsworth Center, New York State Department of Health, Albany 12201 0509, USA
    J Immunol Methods 212:69-78. 1998
    ..separation system based on the calcium-dependent interaction of calmodulin (CM) with a calmodulin-binding peptide (CBP) has been developed. The prototype of this system utilizes an indirect method to label the target cell population...
  35. ncbi Corn expressing an Escherichia coli-derived phytase gene: a proof-of-concept nutritional study in pigs
    E K D Nyannor
    Department of Animal Science, Purdue University, West Lafayette, IN 47907 2054, USA
    J Anim Sci 85:1946-52. 2007
    ..investigate the concept that the addition of corn expressing an Escherichia coli-derived gene (corn-based phytase; CBP) to a P-deficient diet would improve growth performance and P utilization in pigs. An E...
  36. ncbi Role of the transcriptional coactivator CBP/p300 in linking basic helix-loop-helix and CREB responses for follicle-stimulating hormone-mediated activation of the transferrin promoter in Sertoli cells
    J Chaudhary
    Center for Reproductive Biology, School of Molecular Biosciences, Washington State University, Pullman, Washington 99164 4231, USA
    Biol Reprod 65:568-74. 2001
    ..Such an interaction can be mediated by transcriptional integrators such as CREB-binding protein (CBP) and/or p300 and may stabilize the binding of trans-acting factors to their respective cis-elements...
  37. ncbi NF-kappaB/PPAR gamma and/or AP-1/PPAR gamma 'on/off' switches and induction of CBP in colon adenocarcinomas: correlation with COX-2 expression
    Panagiotis A Konstantinopoulos
    Department of Biochemistry, School of Medicine, University of Patras, 26110, Patras, Greece
    Int J Colorectal Dis 22:57-68. 2007
    ..a signaling intermediate of NF-kappaB pathway), PPAR gamma, cyclic AMP-response element binding-binding protein (CBP, a known AP-1, NF-kappaB, and PPAR gamma transcriptional coactivator), epidermal growth factor receptor (EGF-R), ..
  38. ncbi Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles
    S Chakraborty
    Department of Pathology and The Cancer Center, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Biol Chem 276:44936-43. 2001
    ..The second group includes the two co-activators cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF), both of which have histone acetyltransferase (HAT) activity...
  39. ncbi Expression of steroid receptor coactivators and corepressors in human endometrial hyperplasia and carcinoma with relevance to steroid receptors and Ki-67 expression
    Junko Uchikawa
    Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Asahi, Matsumoto, Japan
    Cancer 98:2207-13. 2003
    ..as coactivators (steroid receptor coactivator 1 [SRC-1] and p300/cyclic AMP-response element-binding protein (p300/CBP]) and corepressors (nuclear receptor corepressor [NCoR] and silencing mediator for retinoid and thyroid-hormone ..
  40. ncbi Clinical application of retrograde cerebral perfusion for brain protection during surgery of ascending aortic aneurysm--a report of 50 cases
    Peiqing Dong
    J Extra Corpor Technol 34:101-6. 2002
    ..To protect the brain, deep hypothermic circulatory arrest (DHCA) combined with retrograde cerebral perfusion (RCP) through superior vena cava (N = 50) and simple DHCA (N = 15) were used during the procedure...
  41. pmc E1A-mediated repression of progesterone receptor-dependent transactivation involves inhibition of the assembly of a multisubunit coactivation complex
    Y Xu
    Population Council, The Rockefeller University, New York, New York 10021, USA
    Mol Cell Biol 20:2138-46. 2000
    ..a multisubunit receptor-coactivator complex containing two previously described coactivators, CREB-binding protein (CBP) and steroid receptor coactivator 1 (SRC-1, a member of the p160 family of coactivators), in nuclear extracts of ..
  42. doi Characterization of the complement inhibitory function of rhesus rhadinovirus complement control protein (RCP)
    Marcin Okroj
    Department of Laboratory Medicine, Lund University, University Hospital Malmo, Malmo S 20502, Sweden
    J Biol Chem 284:505-14. 2009
    ..follows: Kaposi sarcoma-associated herpesvirus-complement control protein (KCP) and RRV-complement control protein (RCP). Previously we characterized in detail the functional properties of KCP as a complement inhibitor...
  43. ncbi Acetylation of importin-alpha nuclear import factors by CBP/p300
    A J Bannister
    Department of Pathology, Wellcome CRC Institute, University of Cambridge, Cambridge, CB2 1QR, UK
    Curr Biol 10:467-70. 2000
    ..We asked whether the acetylase CREB-binding protein (CBP) could acetylate proteins not directly involved in transcription...
  44. ncbi Expression of cAMP response element binding protein (CREB)-binding protein (CBP) and the implication in retinoic acid-inducible transcription activation in human salivary gland adenocarcinoma cell line HSG
    S Kyakumoto
    Department of Biochemistry, Iwate Medical University School of Dentistry, Chuodori, Morioka, Iwate, Japan
    Endocr Res 29:277-89. 2003
    ..interacts with a coactivator complex composed of various transcription cofactors such as CREB-binding protein (CBP)/p300 and p160 family member proteins represented by steroid receptor coactivator-1 (SRC-1)/NCoA1 and p300/CBP ..
  45. ncbi Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer
    G Zhou
    Department of Biochemistry and Physiology, Merck Research Laboratories, Rahway, New Jersey 07065, USA
    Mol Endocrinol 12:1594-604. 1998
    ..in FRET between the fluorescently labeled LBD and fluorescently labeled coactivators [CREB-binding protein (CBP) or steroid receptor coactivator-1 (SRC-1)]...
  46. ncbi Association between dorsolateral prefrontal N-acetyl aspartate and depression in chronic back pain: an in vivo proton magnetic resonance spectroscopy study
    I D Grachev
    Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    J Neural Transm 110:287-312. 2003
    ..Inventory), and pain (as measured by short form of the McGill Pain Questionnaire) in 10 chronic back pain (CBP) patients with depression, and compared to the relationship between regional brain NAA levels and depression in 10 ..
  47. pmc cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1)
    E S Silverman
    Vascular Research Division, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Biochem J 336:183-9. 1998
    ..The transcriptional co-activators CBP (cAMP-response-element-binding-protein-binding protein) and p300 interact with sequence-specific transcription ..
  48. ncbi Assessing neuromuscular block at the larynx: the effect of change in resting cuff pressure and a comparison with video imaging in anesthetized humans
    K J Girling
    University Department of Anaesthesia, University Hospital, Queen s Medical Centre, Nottingham, United Kingdom
    Anesth Analg 88:426-31. 1999
    ..In this study, we evaluated the decrease in resting cuff pressure (RCP) after the administration of rocuronium and the effect of this decrease on the assessment of NMB, and we compared ..
  49. ncbi The relevance and recognition of Latin American science. Introduction to the fourth issue of CBP-Latin America
    Marcelo Hermes-Lima
    Oxyradical Research Group, Departamento de Biologia Celular, Universidade de Brasilia, Brasilia, DF, 70910 900, Brazil
    Comp Biochem Physiol C Toxicol Pharmacol 146:1-9. 2007
    ..is to verify which of these interpretations best applies for the field of comparative biochemistry and physiology (CBP)...
  50. ncbi Utilization of oil by-product from the purification process of conjugated linoleic Acid as feeding supplements for the accumulation of conjugated linoleic acid in the egg yolk
    J H Kim
    Department of Food and Biotechnology, Korea University, Chungnam, Korea
    Poult Sci 87:64-70. 2008
    ..The CLA by-product (CBP) was fed to the laying hens to accumulate CLA in the egg yolk...
  51. pmc The transcriptional regulator CBP has defined spatial associations within interphase nuclei
    Kirk J McManus
    Department of Oncology, Cross Cancer Institute, Edmonton, Alberta, Canada
    PLoS Comput Biol 2:e139. 2006
    ..The CREB-binding protein (CBP) is one such transcriptional regulator that, when visualised by confocal microscopy, reveals a highly punctate ..
  52. pmc Identification of Legionella pneumophila rcp, a pagP-like gene that confers resistance to cationic antimicrobial peptides and promotes intracellular infection
    M Robey
    Department of Microbiology Immunology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Infect Immun 69:4276-86. 2001
    ..resistance to different structural classes of CAMPs compared to the wild type; hence, this gene was designated rcp for resistance to cationic antimicrobial peptides...
  53. ncbi Respiratory compensation point during incremental exercise as related to hypoxic ventilatory chemosensitivity and lactate increase in man
    N Takano
    Physiology Laboratory, Department of School Health, Faculty of Education, Kanazawa University, Kanazawa, 920 1192 Japan
    Jpn J Physiol 50:449-55. 2000
    ..lower VO2, termed the ventilatory threshold (VT); and another at a higher VO2, the respiratory compensation point (RCP)...
  54. doi Minilaparotomy radical cystoprostatectomy (Minilap RCP) in the surgical management of urinary bladder carcinoma: early experience
    Sudhir Rawal
    Department of Uro Oncology, Rajiv Gandhi Cancer Institute and Research Center, Rohini, New Delhi 110085, India
    Jpn J Clin Oncol 38:611-6. 2008
    To assess the feasibility of minilaparotomy for radical cystoprostatectomy (RCP) and urinary diversion in the management of urinary bladder carcinoma.
  55. ncbi [Cysteamine attenuates suppression of peripheral IL-2 and lymphocytic proliferation induced by ruminal and duodenal operations in goats]
    Zan Ming Shen
    College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China
    Shi Yan Sheng Wu Xue Bao 37:501-6. 2004
    ..pre-Op), which contained 3 d of roughage-fed period (RP) and 10 d of roughage + concentrate-fed period (RCP), followed by first operation (Op-1) and then the second operation (Op-2)...
  56. pmc HDAC inhibition modulates hippocampus-dependent long-term memory for object location in a CBP-dependent manner
    Jakob Haettig
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, California 92697 3800, USA
    Learn Mem 18:71-9. 2011
    ..enzymes, such as the histone acetyltransferase (HAT) CREB (cyclic-AMP response element binding) binding protein (CBP), are pivotal for the transcriptional regulation required for long-term memory...
  57. ncbi Inactivation of mRNA cap-binding protein complex in Drosophila melanogaster embryos under heat shock
    J M Zapata
    Centro de Biologia Molecular, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    J Biol Chem 266:16007-14. 1991
    We have studied the role of Drosophila 35-kDa cap-binding protein (CBP) and CBP complex in the mechanism of messenger RNA discrimination established in heat-shocked Drosophila embryos...
  58. ncbi Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300
    D Monte
    Laboratory of Molecular Endocrinology, CHUL Research Centre and Laval University, Sainte Foy, Quebec, G1V 4G2, Canada
    J Biol Chem 273:4585-91. 1998
    ..reporter constructs which responded to SF-1 were further stimulated by exogenous p300 and CREB-binding protein (CBP), suggesting interaction between SF-1 and p300/CBP...
  59. ncbi Exposure to cadmium and conventional and ambulatory blood pressures in a prospective population study. Public Health and Environmental Exposure to Cadmium Study Group
    J A Staessen
    Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement voor Cardiovasculair en Moleculair Onderzoek, Katholieke Universiteit Leuven, Belgium
    Am J Hypertens 13:146-56. 2000
    ..follow-up (1991 to 1995; re-examination rate, 81%), blood pressure was measured by conventional sphygmomanometry (CBP; 15 readings in total) and, at follow-up, also by 24-h ambulatory blood pressure monitoring (ABP)...
  60. pmc Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus
    Olivier Bousiges
    INSERM, U692, Laboratoire de Signalisations Moléculaires et Neurodégénérescence, Strasbourg, France
    Neuropsychopharmacology 35:2521-37. 2010
    Numerous genetic studies have shown that the CREB-binding protein (CBP) is an essential component of long-term memory formation, through its histone acetyltransferase (HAT) function...
  61. pmc Distinct embryonic expression and localization of CBP and p300 histone acetyltransferases at the mouse alphaA-crystallin locus in lens
    Ying Yang
    Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, NY10461, USA
    J Mol Biol 369:917-26. 2007
    ..Here, we identified CREB-binding protein (CBP) and p300 as major histone acetyltransferases (HATs) associated in vivo with the mouse alphaA-crystallin locus...
  62. ncbi The calcium binding proteins calbindin, parvalbumin, and calretinin have specific patterns of expression in the gray matter of cat spinal cord
    Roberta Anelli
    Department of Physiology, Northwestern Feinberg School of Medicine, Chicago, Illinois, USA
    J Neurocytol 34:369-85. 2005
    ..However, knowledge on the cellular regulation governing such cell-specific CBP expression is still incomplete...
  63. doi Anti-inflammatory and antimicrobial effects of garlic and synergistic effect between garlic and ciprofloxacin in a chronic bacterial prostatitis rat model
    Dong Wan Sohn
    Department of Urology, College of Medicine, The Catholic University of Korea, St Mary s Hospital, 62 Youido dong, Youngdungpoku, Seoul 150 713, South Korea
    Int J Antimicrob Agents 34:215-9. 2009
    Chronic bacterial prostatitis (CBP), which is characterised by recurrent urinary tract infection (UTI) and persistence of pathogenic bacteria and evidence of inflammation in the prostatic secretions, is one of the most common causes of ..
  64. ncbi Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the Rubinstein-Taybi syndrome
    R I Blough
    Children s Hospital Research Foundation, Division of Human Genetics, Cincinnati, OH 45229 1933, USA
    Am J Med Genet 90:29-34. 2000
    Most reported microdeletions of the CREB-binding protein (CBP) gene in the Rubinstein-Taybi syndrome (RTS) were detected by fluorescence in situ hybridization (FISH) with a single cosmid probe specific to the 3' region of the gene...
  65. pmc Complementation analysis and regulation of CO2 fixation gene expression in a ribulose 1,5-bisphosphate carboxylase-oxygenase deletion strain of Rhodospirillum rubrum
    D L Falcone
    Department of Microbiology, Ohio State University, Columbus 43210 1192
    J Bacteriol 175:5066-77. 1993
    ..rubrum DNA fragments that contain the gene encoding RubisCO, cbbM. When the R. rubrum cbbM deletion strain harbored plasmids containing R. rubrum DNA inserts with at least 2...
  66. ncbi [Comparison and reproducibility of 4 methods of indirect blood pressure measurement in moderate hypertension]
    T Denolle
    Cabinet de Cardiologie, Dinard
    Arch Mal Coeur Vaiss 88:1165-70. 1995
    ..repeated automatic BP measurements during the 20 minutes preceding the physician examination (RABP) and clinic BP (CBP) with a standard sphygmomanometer mercury column...
  67. doi Measurement accuracy of a stand-alone oscillometric central blood pressure monitor: a validation report for Microlife WatchBP Office Central
    Hao Min Cheng
    The Joanna Briggs Institute, Faculty of Health Sciences, University of Adelaide, Australia
    Am J Hypertens 26:42-50. 2013
    The superiority of prognostic value of blood pressure (BP) measured at central aorta (CBP) over conventional brachial BP measured by cuff-based BP monitors has reignited the development of new noninvasive techniques for estimating CBP...
  68. ncbi Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders
    Caroline Rouaux
    Laboratoire de Signalisation Moléculaire et Neurodégénérescence EA 3433 11, rue Humann, 67085 Strasbourg Cedex, France
    Biochem Pharmacol 68:1157-64. 2004
    ..Among the enzymes involved in this process, the CREB-binding protein (CBP) displays important functions during central nervous system development...
  69. doi Improving RhoA-mediated intestinal epithelial permeability by continuous blood purification in patients with severe acute pancreatitis
    Qing Shen
    Department of Nephrology, First Affiliated Hospital of Chongqing Medical University, Chongqing China
    Int J Artif Organs 36:812-20. 2013
    ..A rising number of clinical data have showed that continuous blood purification (CBP) may improve the prognosis of SAP...
  70. doi Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones
    Naoko Sekino-Suzuki
    Laboratory of Biomembrane, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    J Neurochem 124:514-22. 2013
    ..antibody to the ganglioside GD3 (R24) immunoprecipitated the Csk (C-terminal src kinase)-binding protein (Cbp)...
  71. ncbi Germ cell-specific localization of immunoreactive riboflavin carrier protein in the male golden hamster: appearance during spermatogenesis and role in sperm function
    A Sreekumar
    Department of Molecular Reproduction, Development and Genetics and Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560 012, India
    Reproduction 129:577-87. 2005
    Riboflavin carrier protein (RCP) is a phosphoglycoprotein (37 kDa) that is well studied in chicken...
  72. pmc Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells
    Anamaria Brozovic
    Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia
    PLoS ONE 8:e76397. 2013
    The major obstacle of successful tumor treatment with carboplatin (CBP) is the development of drug resistance...
  73. ncbi Growth during the cell cycle
    J M Mitchison
    Institute for Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, UK
    Int Rev Cytol 226:165-258. 2003
    ..the rate of increase stays constant through much of the cycle but it doubles sharply at a rate change point (RCP)...
  74. pmc The transcriptional co-activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen- and anti-androgen-induced androgen receptor function
    Barbara Comuzzi
    Department of Urology, University of Innsbruck, Innsbruck, Austria
    Am J Pathol 162:233-41. 2003
    ..it was shown that the transcriptional co-activator CREB (cAMP response element-binding protein)-binding protein (CBP) enhances AR activity in a ligand-dependent manner...
  75. ncbi Expression of the transcriptional coactivators CBP and p300 in the hamster suprachiasmatic nucleus: possible molecular components of the mammalian circadian clock
    Paul Fiore
    Department of Biology, Dowling College, Oakdale, NY 11769, USA
    Brain Res Mol Brain Res 111:1-7. 2003
    ..The nuclear proteins CBP and p300 are known to be coactivators with pCREB in certain cell types, but their identification within the rodent ..
  76. doi E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300
    Brandy D Hyndman
    Department of Pathology and Molecular Medicine, Queen s University, Canada
    Biochim Biophys Acta 1819:446-53. 2012
    ..CREB binding protein (CBP) and its close paralog p300 are transcriptional co-activators with intrinsic histone acetyltransferase (HAT) ..
  77. doi Use of the reciprocal calculation procedure for setting workplace emergency action levels for hydrocarbon mixtures and their relationship to lower explosive limits
    Ron Gardner
    Hawkes Associates, for the Energy Institute, 61 New Cavendish Street, London W1G 7AR, UK
    Ann Occup Hyg 56:326-39. 2012
    This paper proposes a novel use of the reciprocal calculation procedure (RCP) to calculate workplace emergency action levels (WEALs) for accidental releases of hydrocarbon mixtures...
  78. doi Genetic polymorphisms in hMTH1, hOGG1 and hMYH and risk of chronic benzene poisoning in a Chinese occupational population
    Fen Wu
    Department of Occupational Health and Toxicology, School of Public Health, Fudan University, Shanghai, China
    Toxicol Appl Pharmacol 233:447-53. 2008
    ..to DNA induced by benzene is an important mechanism of its genotoxicity, which leads to chronic benzene poisoning (CBP)...
  79. pmc An essential role for p300/CBP in the cellular response to hypoxia
    Z Arany
    Dana Farber Cancer Institute, Boston, MA, USA
    Proc Natl Acad Sci U S A 93:12969-73. 1996
    p300 and CBP are homologous transcription adapters targeted by the E1A oncoprotein. They participate in numerous biological processes, including cell cycle arrest, differentiation, and transcription activation...
  80. doi Low-frequency vibrational modes and infrared absorbance of red, blue and green opsin
    Saravana Prakash Thirumuruganandham
    Fachbereich Physik und Forschungszentrum OPTIMAS, Universitat Kaiserslautern, Erwin Schrodinger Strasse, 67663, Kaiserslautern, Germany
    J Mol Model 15:959-69. 2009
    ..We thus demonstrate that terahertz spectroscopy of low-frequency modes might be relevant for identifying those vibrational degrees of freedom that correlate to known conformational changes in opsins...
  81. ncbi A new mechanism in blue cone monochromatism
    A S Ladekjaer-Mikkelsen
    Institute of Human Genetics, University of Aarhus, Denmark
    Hum Genet 98:403-8. 1996
    ..Here we describe a clinical case of BCM caused by a new mutation where exon 4 of an isolated red pigment gene has been deleted. The finding represents the first intragenic deletion yet described among red and green pigment genes...
  82. ncbi Modulating effects of bile salt hydrophobicity on bile secretion of the major protein of the bile lipoprotein complex
    N Domingo
    INSERM Unité 130, Marseille, France
    Lipids 28:883-7. 1993
    ..with a newly identified major apoprotein called anionic polypeptide fraction-calcium binding protein (APF-CBP), which is synthesized in the hepatocytes and has been detected in both bile and plasma and characterized...
  83. ncbi [Properties of energy transfer in two host materials doped with Ir(ppy)3 and Rubrene]
    Yan Rui Li
    Key Laboratory of Luminescence and Optical Information, Beijing Jiaotong University, Ministry of Education, Beijing 100044, China
    Guang Pu Xue Yu Guang Pu Fen Xi 29:1-5. 2009
    ..Respectively, the two kinds of host are polyvinylcarbazole [PVK] and 4,4'-N,N-dicarbazole-biphenyl [CBP]. We studied the properties of energy transfer between host materials and dopants...
  84. doi Corn expressing an Escherichia coli-derived phytase gene: residual phytase activity and microstructure of digesta in broiler chicks
    E K D Nyannor
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Poult Sci 88:1413-20. 2009
    ..The phytase activity of the corn expressing phytase (CBP) was determined to be 660 phytase units/g and was incorporated into broiler diets at varying rates...
  85. ncbi Completion of the physical map of Xq28: the location of the gene for L1CAM on the human X chromosome
    A Dietrich
    Deutsches Krebsforschungszentrum, Heidelberg, FRG
    Mamm Genome 3:168-72. 1992
    ..With pulsed field gel electrophoresis it has been proposed that L1CAM lies between the RCP, GCP, and GDX, G6PD loci...
  86. ncbi Antihypertensive treatment based on conventional or ambulatory blood pressure measurement. A randomized controlled trial. Ambulatory Blood Pressure Monitoring and Treatment of Hypertension Investigators
    J A Staessen
    Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement voor Moleculair en Cardiovasculaire Onderzoek, Katholieke Universiteit Leuven, Belgium
    JAMA 278:1065-72. 1997
    ..Ambulatory blood pressure (ABP) monitoring is used increasingly in clinical practice, but how it affects treatment of blood pressure has not been determined...
  87. ncbi Drosophila CBP is required for dorsal-dependent twist gene expression
    H Akimaru
    Laboratory of Molecular Genetics, Tsukuba Life Science Center, RIKEN, Ibaraki, Japan
    Nat Genet 17:211-4. 1997
    Although CREB-binding protein (CBP) functions as a co-activator of many transcription factors, relatively little is known about the physiological role of CBP...
  88. doi Is "usual" blood pressure a proxy for 24-h ambulatory blood pressure in predicting cardiovascular outcomes?
    Jerzy Gasowski
    Department of Internal Medicine and Gerontology, Jagiellonian University, Krakow, Poland
    Am J Hypertens 21:994-1000. 2008
    ..ambulatory blood pressure (ABP) is a stronger predictor of cardiovascular disease than conventional blood pressure (CBP), but it remains unclear how it compares with "usual" blood pressure (UBP), estimated after CBP has been corrected ..
  89. ncbi [Effects of predator stress on the expression of cAMP responsive element binding protein in hippocampus: experiment with rats]
    Qing Song Wang
    Department of Neurology, Chengdu Army General Hospital, Chengdu 610083, China
    Zhonghua Yi Xue Za Zhi 87:3367-71. 2007
    ..To explore the neurobiological basis involved in the pathogenesis of the lasting emotionality and cognitive impairment following severe psychological stress...
  90. pmc Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3
    Weijun Chen
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    J Mol Biol 379:251-60. 2008
    ..This phosphoactivation triggers IRF-3 to react with the coactivators, CREB-binding protein (CBP)/p300, to form a complex that activates target genes in the nucleus...
  91. pmc Structural features responsible for the biological stability of Histoplasma's virulence factor CBP
    Moriah R Beck
    Department of Molecular Microbiology, Washington University, St Louis, Missouri 63110, USA
    Biochemistry 47:4427-38. 2008
    The virulence factor CBP is the most abundant protein secreted by Histoplasma capsulatum, a pathogenic fungus that causes histoplasmosis...
  92. doi CREB-binding proteins (CBP) as a transcriptional coactivator of GATA-2
    HuiJie Jiang
    College of Life Sciences, Ludong University, Yantai, 264025, China
    Sci China C Life Sci 51:191-8. 2008
    ..CREB-binding proteins (CBP) are essential transcriptional coactivators for a large number of regulated DNA-binding transcription factors, ..
  93. ncbi [Immune and inflammation confusion in severe sepsis and effects of bi-immunomodulation therapy: a prospective, randomized, controlled clinical trial]
    Li Xin Zhou
    Intensive Care Unit, First Hospital of Foshan, Foshan 528000, China
    Zhonghua Yi Xue Za Zhi 89:1028-33. 2009
    To investigate the immune and inflammation confusion state in severe sepsis and the effects of two way immunomodulation therapy with continuous blood purification (CBP), thymosin alpha1, and combined therapy of CBP and thymosin alpha(1).
  94. doi Portability of the GN(R)A hairpin loop motif between RNA and DNA
    Joshua M Blose
    Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Biochemistry 48:8787-94. 2009
    ..mimicry and electrostatic factors to attain exceptional thermodynamic stability with a CG closing base pair (cbp)...
  95. pmc Purification and characterization of recombinant CH3 domain fragment of the CREB-binding protein
    Catherine Ibarra Drendall
    Department of Medicine, Duke University Medical Center, Box 2628, Durham, NC 27710, USA
    Protein Expr Purif 70:196-205. 2010
    CREB-binding protein (CBP) is an important coactivator of basal transcription machinery and a critical regulator of cellular proliferation, differentiation, and apoptosis...
  96. doi Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development
    Zhu Chen
    State Key Laboratory of Oral Disease, West China College of Stomatology, Sichuan University, Chengdu, 610041, China
    In Vitro Cell Dev Biol Anim 48:61-8. 2012
    The transcription coactivators p300 and CBP were reported to have indispensable roles in various tissues during the embryonic and fetal stages...
  97. pmc Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src
    Aaron T Place
    Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA
    Mol Pharmacol 80:665-72. 2011
    In the present study, we assessed the cooperative roles of C-terminal Src kinase (Csk) binding protein (Cbp) and Caveolin-1 (Cav-1) in the mechanism of Src family tyrosine kinase (SFK) inhibition by Csk...
  98. pmc Presenilin1/gamma-secretase promotes the EphB2-induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein
    Anastasios Georgakopoulos
    Center for Molecular Biology and Genetics of Neurodegeneration, Department of Psychiatry, Mt Sinai School of Medicine, New York University, 1 Gustave L Levy Pl, Box 1229, New York, NY 10029, USA
    FASEB J 25:3594-604. 2011
    ..regulation of phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein (PAG/Cbp), an adaptor protein that controls the activity of Src kinases...
  99. doi The effectiveness of high-flow regional cerebral perfusion in Norwood stage I palliation
    Kagami Miyaji
    Department of Cardiovascular Surgery, Kitasato University School of Medicine, Sagamihara, Japan
    Eur J Cardiothorac Surg 40:1215-20. 2011
    Regional cerebral perfusion (RCP) has been shown to provide cerebral circulatory support during Norwood procedure...
  100. pmc Down-regulation of the tumor suppressor C-terminal Src kinase (Csk)-binding protein (Cbp)/PAG1 is mediated by epigenetic histone modifications via the mitogen-activated protein kinase (MAPK)/phosphatidylinositol 3-kinase (PI3K) pathway
    Kei Suzuki
    Department of Oncogene Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    J Biol Chem 286:15698-706. 2011
    The transmembrane adaptor protein Cbp (or PAG1) functions as a suppressor of Src-mediated tumor progression by promoting the inactivation of Src...

Research Grants79

  1. Roles of CBP & PCAF During Hematopoietic Differentiation
    GERD BLOBEL; Fiscal Year: 2005
    ..One class of such enzymes consists of histone acetyltransferases which includes the widely expressed molecules CBP, its close relative p300, and the p300/CBP-associated factor PCAF...
  2. Structure/Function of Histone Acetyltransferases
    Ronen Marmorstein; Fiscal Year: 2009
    ..Aberrant HAT function has also been correlated with human disease, including leukemic translocations involving the CBP and MOZ HATs, and p300 HAT alterations in colorectal and gastric cancers...
  3. Structure/Function of Histone Acetyltransferases
    Ronen Marmorstein; Fiscal Year: 2010
    ..Aberrant HAT function has also been correlated with human disease, including leukemic translocations involving the CBP and MOZ HATs, and p300 HAT alterations in colorectal and gastric cancers...
  4. Structure/Function of Histone Acetyltransferases
    Ronen Marmorstein; Fiscal Year: 2011
    ..Aberrant HAT function has also been correlated with human disease, including leukemic translocations involving the CBP and MOZ HATs, and p300 HAT alterations in colorectal and gastric cancers...
  5. CONTROL OF P53 TUMOR SUPPRESSOR BY CBP/P300
    Tso Pang Yao; Fiscal Year: 2005
    DESCRIPTION (from the application): The long-term objective of this proposal is to elucidate the function of CBP and its family member p300 in cellular growth and oncogenesis...
  6. Long-range function of the ERV-9 LTR in regulating globin gene switching
    Dorothy Tuan; Fiscal Year: 2009
    ..We subsequently found that in the LTR Tg mice, LTR deletion lowered the levels of NF-Y, GATA-2 and CBP on the ?-globin promoter but increased the levels of these factors on the ?-globin promoter in adult erythroid ..
  7. Long-range function of the ERV-9 LTR in regulating globin gene switching
    DOROTHY Y TUAN; Fiscal Year: 2010
    ..We subsequently found that in the LTR Tg mice, LTR deletion lowered the levels of NF-Y, GATA-2 and CBP on the ?-globin promoter but increased the levels of these factors on the ?-globin promoter in adult erythroid ..
  8. Regulation of NFkappaB activity by the Estrogen Receptor
    Kendall W Nettles; Fiscal Year: 2010
    ..This hypothesis will be pursued in the following Specific Aims: SPECIFIC AIM 1. To investigate the importance of CBP and Grip1 in the molecular interactions required for ER-mediated suppression of NF-B, we will measure their ..
  9. Regulation of NFkappaB activity by the Estrogen Receptor
    Kendall W Nettles; Fiscal Year: 2010
    ..This hypothesis will be pursued in the following Specific Aims: SPECIFIC AIM 1. To investigate the importance of CBP and Grip1 in the molecular interactions required for ER-mediated suppression of NF-B, we will measure their ..
  10. REGULATION OF GROWTH FACTORS AND EMBRYOGENESIS
    ARNOLD RIZZINO; Fiscal Year: 2005
    ..its effects? Recent studies argue that Sox-2 and Oct-3 can mediate their effects through the co-activators p300 and CBP (p300/CBP)...
  11. Regulation of HTLV-1 and cellular gene transcription by the viral protein HBZ
    ISABELLE MICHELE LEMASSON; Fiscal Year: 2010
    ..We found that HBZ also binds directly to the cellular coactivators p300 and CBP, which is mediated through regions of the viral protein outside its bZIP domain...
  12. TRANSCRIPTION FACTOR INTERACTIONS AT THE GH PROMOTER
    Fred Schaufele; Fiscal Year: 2001
    ..factor C/EBPalpha cooperates with the pituitary-specific transcription factor Pit-1 and the coactivator CBP to control protein kinase A and C-regulated GH gene transcription...
  13. Mechanisms of p53 activation in tumorsuppression
    Wei Gu; Fiscal Year: 2010
    ..In our early studies, we found that histone acetyltransferase CBP/p300 promotes p53-dependent transcription by directly acetylating lysine residues in the C-terminal region of p53...
  14. C/EBP, atrogin-1, and muscle wasting
    Per Olof Hasselgren; Fiscal Year: 2007
    ..In particular, the role of the transcription factor C/EBP and nuclear co-factors p300/CBP for regulation of genes in the ubiquitin-proteasome pathway has not been defined...
  15. Characterization of Neuroendocrine CGRP Receptors
    Ian Dickerson; Fiscal Year: 2006
    We have discovered a 148 aa protein named calcitonin gene-related peptide (CGRP)-receptor component protein (RCP) that is required for G protein-coupled signal transduction at receptors for the neuropeptide CGRP...
  16. Chemical Modulators for p53 Functions in Transcriptional Regulation
    SYED S MUJTABA; Fiscal Year: 2010
    ..Our study revealed that p53 recruitment of the co-activator CBP (CREB binding protein) requires association of the conserved bromodomain of CBP (CBP BRD) with p53 at acetylated ..
  17. Chemical Modulators for p53 Functions in Transcriptional Regulation
    SYED S MUJTABA; Fiscal Year: 2011
    ..Our study revealed that p53 recruitment of the co-activator CBP (CREB binding protein) requires association of the conserved bromodomain of CBP (CBP BRD) with p53 at acetylated ..
  18. SRCAP Regulation of CREB and GR-mediated Transcription
    John Chrivia; Fiscal Year: 2005
    CREB-binding protein (CBP) functions as a coactivator for many transcription factors and is able to respond to extracellular signals to specifically regulate gene expression...
  19. Molecular Functions of the Adenovirus E1A Oncogene
    Maurice Green; Fiscal Year: 2006
    ..A large panel of EIA single amino acid substitution mutants will be used to define interactions among E1A, p300/CBP, and TBP and to establish their relevance to the E1A repression function...
  20. STRUCTURE AND FUNCTION OF SV40 NON-VIRION PROTEINS
    David Livingston; Fiscal Year: 2007
    Abstract: The specific aims of the ongoing work are : 1) to understand how p300 and CBP participate in the operations of hematopoietic stem cells and, as such, to learn how they operate as hematopoeitic tumor suppressing elements; 2) to ..