OAS3

Summary

Gene Symbol: OAS3
Description: 2'-5'-oligoadenylate synthetase 3
Alias: p100, p100OAS, 2'-5'-oligoadenylate synthase 3, (2-5')oligo(A) synthase 3, (2-5')oligo(A) synthetase 3, 2'-5'-oligoadenylate synthetase 3, 100kDa, 2'-5'oligoadenylate synthetase p100, 2-5A synthase 3, 2-5A synthetase 3, p100 OAS
Species: human
Products:     OAS3

Top Publications

  1. Tewari V, Mehta R, Sreedhar C, Tewari K, Mohammad A, Gupta N, et al. A novel homozygous mutation in POLR3A gene causing 4H syndrome: a case report. BMC Pediatr. 2018;18:126 pubmed publisher
    ..brainstem evoked response audiometry and her fundus examination showed bilateral optic atrophy with prolongation of P100 latencies on visual evoked potentials...
  2. Petersheim D, Massaad M, Lee S, Scarselli A, Cancrini C, Moriya K, et al. Mechanisms of genotype-phenotype correlation in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency. J Allergy Clin Immunol. 2018;141:1060-1073.e3 pubmed publisher
    ..Canonical NF-κB-dependent IL-6 secretion and upregulation of the NF-κB subunit 2/p100 and RELB proto-oncogene, NF-κB subunit (RelB) components of the noncanonical NF-κB pathway were diminished ..
  3. Weidemann A, Lovas A, Rauch A, Andreas N, von Maltzahn J, Riemann M, et al. Classical and alternative NF-κB signaling cooperate in regulating adipocyte differentiation and function. Int J Obes (Lond). 2016;40:452-9 pubmed publisher
    ..This LTβR-mediated pathway was synergistically regulated via a TNF-induced increase in p100 and RelB expression and nuclear translocation...
  4. Eckhardt I, Weigert A, Fulda S. Identification of IRF1 as critical dual regulator of Smac mimetic-induced apoptosis and inflammatory cytokine response. Cell Death Dis. 2014;5:e1562 pubmed publisher
    ..target genes, as IRF1 depletion attenuates BV6-stimulated upregulation of TNFα and interleukin-8 (IL-8) but not p100 and RelB...
  5. Kaufman K, Jenkins Y, Alomari M, Mirzaei M, Best O, Pascovici D, et al. The Hsp90 inhibitor SNX-7081 is synergistic with fludarabine nucleoside via DNA damage and repair mechanisms in human, p53-negative chronic lymphocytic leukemia. Oncotarget. 2015;6:40981-97 pubmed publisher
    ..cell death is triggered following reductions of MYC and nucleolin and an accumulation of apoptosis-inducing NFkB2 p100 subunit...
  6. Corrêa F, Schanuel F, Moura Nunes N, Monte Alto Costa A, Daleprane J. Brazilian red propolis improves cutaneous wound healing suppressing inflammation-associated transcription factor NF?B. Biomed Pharmacother. 2017;86:162-171 pubmed publisher
    ..doses of vehicle solution (water-alcohol solution containing 2% of ethanol, control group) or 100mg/kg of BRPE (P100 group) during nine consecutive days...
  7. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study. Mult Scler Relat Disord. 2015;4:159-69 pubmed publisher
    ..Visual evoked potentials in two patients exhibited progressive reappearance of P100 waves, with normalization of latencies in one case...
  8. Lachowicz E, Lubinski W. The importance of the electrophysiological tests in the early diagnosis of ganglion cells and/or optic nerve dysfunction coexisting with pituitary adenoma: an overview. Doc Ophthalmol. 2018;137:193-202 pubmed publisher
    ..tests were as follows: in PVEPs-the crossed/uncrossed asymmetry distribution, altered waveform, increase in P100-wave peak time, and/or reduction in amplitude; in mfVEPs-the peak time prolongation and/or amplitude reduction in ..
  9. Hafke A, Schürmann P, Rothämel T, Dork T, Klintschar M. Evidence for an association of interferon gene variants with sudden infant death syndrome. Int J Legal Med. 2019;133:863-869 pubmed publisher
    ..SIDS cases and 336 controls from Germany: ADAR1, CSF2RB, DDX58, IFNA1, IFNA21, IFNA8, IFNAR2, IFNG, IL6, MX2, OAS1, OAS3, and TNFA...

More Information

Publications137 found, 100 shown here

  1. Lee H, Lombardi A, Stefan M, Li C, Inabnet W, Owen R, et al. CD40 Signaling in Graves Disease Is Mediated Through Canonical and Noncanonical Thyroidal Nuclear Factor ?B Activation. Endocrinology. 2017;158:410-418 pubmed publisher
    ..Western blot analyses of the specific transcription factors for the NF-?B1 and NF-?B2 pathways (p65 and p100/p52, respectively) demonstrated that p65 is constitutively expressed...
  2. Elkhateeb E, Tag El Din Hassan H, Sasaki N, Torigoe D, Morimatsu M, Agui T. The role of mouse 2',5'-oligoadenylate synthetase 1 paralogs. Infect Genet Evol. 2016;45:393-401 pubmed publisher
    ..to the presence of eight paralogs of Oas1 genes (Oas1a through Oas1h) that forms Oas gene cluster with the Oas2, Oas3 and two OasL (OasL1 and OasL2) genes...
  3. Dominguez Molina B, Machmach K, Perales C, Tarancón Díez L, Gallego I, Sheldon J, et al. Toll-Like Receptor 7 (TLR-7) and TLR-9 Agonists Improve Hepatitis C Virus Replication and Infectivity Inhibition by Plasmacytoid Dendritic Cells. J Virol. 2018;92: pubmed publisher
    ..three virus derivatives-wild-type Jc1, interferon (IFN)-resistant virus IR, and high-replicative-fitness virus P100-in order to explore additional IFN-α-related virus inhibition mechanisms...
  4. Normia J, Niinivirta Joutsa K, Isolauri E, Jääskeläinen S, Laitinen K. Perinatal nutrition impacts on the functional development of the visual tract in infants. Pediatr Res. 2019;85:72-78 pubmed publisher
    ..who consumed fish three or more times per week during the last trimester of pregnancy had a higher pVEP component P100 amplitude for 60' (mean 23.4, SD 8.1) and 30' (mean 20.4, SD 6...
  5. Diotallevi M, Checconi P, Palamara A, Celestino I, Coppo L, Holmgren A, et al. Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties. Front Immunol. 2017;8:1239 pubmed publisher
    ..One group, mapping to innate immunity and antiviral responses (Oas2, Oas3, Mx2, Irf7, Irf9, STAT1, il1b), required GSH for optimal induction...
  6. Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed publisher
    ..The alternative (or non-canonical) pathway, involves the inducible processing of p100 to p52, leading to the induction of NF-κB2(p52)/RelB containing complexes, and is dependent on IKKα and NF-Î..
  7. Lagor W, Fields D, Bauer R, Crawford A, Abt M, Artis D, et al. Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis. Atherosclerosis. 2014;233:234-41 pubmed publisher
    ..Interferon alpha induced gene 27 like 2a (Ifi27l2a), Oligoadenylate synthetases 2 and 3 (Oas2 and Oas3) were significantly reduced in the ApoF KO mice relative to wild type controls...
  8. Whittemore S, White L, Sanon H. Acidic and basic fibroblast growth factor levels in spinal cord cultures are not regulated by alterations in heparan sulfate proteoglycan expression. Int J Dev Neurosci. 1991;9:521-35 pubmed
    ..Solubilized cultures separated on a P100 column showed mitogenic activity for NIH3T3 cells from 17-18 and 24 kDa fractions...
  9. Ma X, Aoki T, Narumiya S. Prostaglandin E2-EP4 signaling persistently amplifies CD40-mediated induction of IL-23 p19 expression through canonical and non-canonical NF-κB pathways. Cell Mol Immunol. 2016;13:240-50 pubmed publisher
    ..mice, and the late phase induction was eliminated by RNA interference of nuclear factor-kappa B (NF-κB) p100 subunit...
  10. Mooster J, Le Bras S, Massaad M, Jabara H, Yoon J, Galand C, et al. Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. J Exp Med. 2015;212:185-202 pubmed publisher
    ..and adhesion molecules mediated by both canonical and noncanonical NF-κB pathways was impaired, and levels of p100 were markedly diminished in the mutant...
  11. Sarnat Kucharczyk M, Pojda Wilczek D, Mrukwa Kominek E. Diagnostic methods in ocular argyrosis: case report. Doc Ophthalmol. 2016;133:129-138 pubmed
    ..PERG abnormalities and delayed latency of P100 wave in PVEP confirmed impaired function of the inner layers of the retina in the macular region...
  12. Magnani M, Crinelli R, Bianchi M, Antonelli A. The ubiquitin-dependent proteolytic system and other potential targets for the modulation of nuclear factor-kB (NF-kB). Curr Drug Targets. 2000;1:387-99 pubmed
    ..The same proteolytic pathway is involved in the processing of the p105 and p100 precursors to generate mature p50 and p52 subunits, respectively...
  13. Chauhan D, Swain D, Shah N, Yadav H, Sharma A, Yadav B, et al. Modulation of voltage-gated sodium channels induces capacitation in bull spermatozoa through phosphorylation of tyrosine containing proteins. Theriogenology. 2018;108:207-216 pubmed publisher
    ..The immune blot study revealed the presence of five tyrosine phosphorylated proteins, namely-p17, p30, p54, p90 and p100. The p17 protein showed the highest band intensity compared to other protein bands indicating its potential ..
  14. Guo G, Ye S, Xie S, Ye L, Lin C, Yang M, et al. The cytomegalovirus protein US31 induces inflammation through mono-macrophages in systemic lupus erythematosus by promoting NF-κB2 activation. Cell Death Dis. 2018;9:104 pubmed publisher
    ..indicated US31 directly interacted with NF-κB2, contribute to the polyubiquitination of the phosphorylated p100 and consequent activation of NF-κB2...
  15. Tessema G, Møretrø T, Snipen L, Axelsson L, Naterstad K. Global transcriptional analysis of spontaneous sakacin P-resistant mutant strains of Listeria monocytogenes during growth on different sugars. PLoS ONE. 2011;6:e16192 pubmed publisher
    ..in stability of the sakacin P resistance phenotype, growth in the presence of both the lytic bacteriophage P100 and activated charcoal...
  16. Jarc Vidmar M, Tajnik M, Brecelj J, Fakin A, Sustar M, Naji M, et al. Clinical and electrophysiology findings in Slovene patients with Leber hereditary optic neuropathy. Doc Ophthalmol. 2015;130:179-87 pubmed publisher
    ..The PERG P50 component was normal in 14/14 eyes, while the N95 component was reduced in 7/14 eyes. VEP wave P100 was reduced and delayed in 14/14 eyes...
  17. García Álvarez M, Berenguer J, Jiménez Sousa M, Pineda Tenor D, Aldamiz Echevarría T, Tejerina F, et al. Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study. Sci Rep. 2017;7:41516 pubmed publisher
    ..DNA genotyping for Mx1 (rs469390), OAS1 (rs2285934), OAS2 (rs1293762) and OAS3 (rs2010604) was performed by using GoldenGate assay...
  18. Zheng N, Wang D, Ming H, Zhang H, Yu X. BAFF promotes proliferation of human mesangial cells through interaction with BAFF-R. BMC Nephrol. 2015;16:72 pubmed publisher
    ..Akt and MAPK p38 kinase in human mesangial cells, whereas it had no effect on the expression of NF-κB p100 and phosphorylation of Erk...
  19. Colla E, Panattoni G, Ricci A, Rizzi C, Rota L, Carucci N, et al. Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons. Neurobiol Dis. 2018;111:36-47 pubmed publisher
    ..Moreover, increasing the amount of P100/M fractions obtained from diseased and, more surprisingly, from presymptomatic mice induced a significant level of ..
  20. Englert J, Cho M, Lamb A, Shumyatcher M, Barragan Bradford D, Basil M, et al. Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation. Respir Res. 2019;20:15 pubmed publisher
    ..01), including IFI44L, OAS3, LY6E, and SPATS2L that had increased expression in ARDS vs...
  21. Balnytė R, Uloziene I, Rastenyte D, Vaitkus A, Malcienė L, Laučkaitė K. Diagnostic value of conventional visual evoked potentials applied to patients with multiple sclerosis. Medicina (Kaunas). 2011;47:263-9 pubmed
    ..The latencies and amplitudes of P100 were measured...
  22. Oliveira M, Abadias M, Colás Medà P, Usall J, Viñas I. Biopreservative methods to control the growth of foodborne pathogens on fresh-cut lettuce. Int J Food Microbiol. 2015;214:4-11 pubmed publisher
    ..different biopreservative methods including M309 strain, Pseudomonas graminis CPA-7 (CPA-7), bacteriophages (Listex P100 and Salmonelex) and nisin at conditions simulating commercial applications against Salmonella and L...
  23. Allam H, Soliman S, Wasfy T, Ghoneim A, Serag Y, Sembajwe G. The neuro-ophthalmological effects related to long-term occupational exposure to organic solvents in painters. Toxicol Ind Health. 2018;34:91-98 pubmed publisher
    ..The exposed group had significantly longer latency and higher amplitude of VEP waves especially P100, higher Color Confusion Index (CCI), especially affecting the blue-yellow spectrum, and lower Log CS...
  24. Dutta P, Ta A, Thakur B, Dasgupta N, Das S. Biphasic Ccl20 regulation by Toll-like receptor 9 through the activation of ERK-AP-1 and non-canonical NF-?B signaling pathways. Biochim Biophys Acta Gen Subj. 2017;1861:3365-3377 pubmed publisher
    ..regulation by AP-1 (cjun/cfos) and non-canonical NF-?B (RelB/p52) downstream of MEK-ERK and NIK-IKK-?-NF-?B2 (p100) phosphorylation, respectively was responsible for persistent Ccl20 expression in the colonic cells, while ..
  25. Melnichuk N, Kashuba V, Rybalko S, Tkachuk Z. Complexes of Oligoribonucleotides with d-Mannitol Modulate the Innate Immune Response to Influenza A Virus H1N1 (A/FM/1/47) In Vivo. Pharmaceuticals (Basel). 2018;11: pubmed publisher
    ..i>cxcl9, cxcl10, cxcl11), interferon-stimulated genes (ISGs) (oas1a, oas2, oas3, mx1), and pro-oxidation (nos2, xdh) genes...
  26. Garcia Martin E, Ara J, Martin J, Almarcegui C, Dolz I, Vilades E, et al. Retinal and Optic Nerve Degeneration in Patients with Multiple Sclerosis Followed up for 5 Years. Ophthalmology. 2017;124:688-696 pubmed publisher
    ..the mean deviation using the GDx-VCC nerve fiber analyzer (Laser Diagnostic Technologies, San Diego, CA) and in the P100 latency of visual evoked potentials; no changes were detected in visual acuity, color vision, or visual fields...
  27. Toma C, Ruberto G, Marzi F, Vandelli G, Signorini S, Valente E, et al. Macular staphyloma in patients affected by Joubert syndrome with retinal dystrophy: a new finding detected by SD-OCT. Doc Ophthalmol. 2018;137:25-36 pubmed publisher
    ..limits in both scotopic and photopic components in the two pairs of siblings and in the fifth subject, with VEP P100 latencies and amplitudes delayed and reduced in all spatial frequencies...
  28. Hahn J, Thalmann S, Migur A, von Boeselager R, Kubatova N, Kubareva E, et al. Conserved small mRNA with an unique, extended Shine-Dalgarno sequence. RNA Biol. 2017;14:1353-1363 pubmed publisher
    ..unique Shine-Dalgarno sequence (SD) with a length of 17 nt was localized predominantly in the ribosome-containing P100 fraction of Bradyrhizobium japonicum USDA 110...
  29. Saxon J, Yu H, Polosukhin V, Stathopoulos G, Gleaves L, McLoed A, et al. p52 expression enhances lung cancer progression. Sci Rep. 2018;8:6078 pubmed publisher
    ..We observed frequent nuclear accumulation of the non-canonical NF-κB component p100/p52 in human lung adenocarcinoma...
  30. Saxon J, Cheng D, Han W, Polosukhin V, McLoed A, Richmond B, et al. p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment. J Immunol. 2016;196:1891-9 pubmed publisher
    ..with acute respiratory distress syndrome, we identified increased expression of the noncanonical pathway component p100/p52...
  31. Lee S, Challa Malladi M, Bratton S, Wright C. Nuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1). J Biol Chem. 2014;289:30680-9 pubmed publisher
    ..Furthermore, in the presence of the NIK IBM mutant, we observed an elevated processing of p100 to p52 followed by increased expression of NF-κB target genes...
  32. Xu J, Hu H, Wright R, Sanchez B, Schnaas L, Bellinger D, et al. Prenatal Lead Exposure Modifies the Impact of Maternal Self-Esteem on Children's Inattention Behavior. J Pediatr. 2015;167:435-41 pubmed publisher
    ..Compared with those among high prenatal lead exposure (P25-P100), this association was stronger among low prenatal lead exposure groups (P1-P25, P values for the interaction ..
  33. Tanwar S, Dhar A, Varanasi V, Mukherjee T, Boppana R, Basak S, et al. Mediation of transitional B cell maturation in the absence of functional Bruton's tyrosine kinase. Sci Rep. 2017;7:46029 pubmed publisher
    ..Xid transitional B cells ex vivo showed low levels of the p100 protein substrate for non-canonical NF-kappaB signalling...
  34. Sharma R, Williams P, Gupta A, McCluskey B, Bhaskaran S, Muñoz S, et al. A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice. Oncotarget. 2015;6:21589-602 pubmed
    ..Levels of p100, IκBα, Mcl-1, ATF4, total and cleaved caspase-3, and phospho-β-catenin were elevated in 5TGM1-∆..
  35. Hogendoorn H, Kammers M, Haggard P, Verstraten F. Self-touch modulates the somatosensory evoked P100. Exp Brain Res. 2015;233:2845-58 pubmed publisher
    ..We show that the P100 SEP component, which has previously been implicated in the conscious perception of a tactile stimulus, is enhanced ..
  36. Verhelst K, Gardam S, Borghi A, Kreike M, Carpentier I, Beyaert R. XEDAR activates the non-canonical NF-κB pathway. Biochem Biophys Res Commun. 2015;465:275-80 pubmed publisher
    ..we report that XEDAR is also able to trigger the non-canonical NF-κB pathway, characterized by the processing of p100 (NF-κB2) into p52, followed by nuclear translocation of p52 and RelB...
  37. Cardini F, Longo M. Congruency of body-related information induces somatosensory reorganization. Neuropsychologia. 2016;84:213-21 pubmed publisher
    ..Results showed stronger SSI in the P100 component after congruent than incongruent stimulation, suggesting the key role of congruent sensory information ..
  38. Ortiz A, Husi H, González Lafuente L, Valiño Rivas L, Fresno M, Sanz A, et al. Mitogen-Activated Protein Kinase 14 Promotes AKI. J Am Soc Nephrol. 2017;28:823-836 pubmed publisher
    ..the NFκB DNA binding heterodimer RelB/NFκB2, and proteins involved in NFκB2 p100 ubiquitination and proteasomal processing to p52, as upregulated...
  39. Willeford K, Fimreite V, Ciuffreda K. The effect of spectral filters on VEP and alpha-wave responses. J Optom. 2016;9:110-7 pubmed publisher
    ..The VEP N75 and P100 latencies, and VEP amplitude, were recorded...
  40. Fan Z, Tong X, Li Y, Yu L, Chen Y, Liu H, et al. [Protective effect of propofol against cerebral ischemic/reperfusion injury may involve inhibition of gap junction]. Nan Fang Yi Ke Da Xue Xue Bao. 2015;35:1678-82 pubmed
    ..into sham-operated group, I/R group, low-, moderate-, and high-dose propofol groups (25, 50, 100 mg/kg; P25, P50, P100 groups, respectively), I/R+CBX group and P100+CBX group...
  41. Yang Y, Xiong S, Cai B, Luo H, Dong E, Li Q, et al. Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production. Sci Rep. 2017;7:44303 pubmed publisher
    ..These effects mainly were mediated by triggering OAS3-RNase L system...
  42. Niechwiej Szwedo E, Chin J, Wolfe P, Popovich C, Staines W. Abnormal visual experience during development alters the early stages of visual-tactile integration. Behav Brain Res. 2016;304:111-9 pubmed publisher
    ..Second, the amplitude of the P100 somatosensory ERP was significantly greater in participants with abnormal vision...
  43. Yoon S, Shim M, Kim H, Lee S. Enhanced Early Posterior Negativity to Fearful Faces in Patients with Anxiety Disorder. Brain Topogr. 2016;29:262-72 pubmed publisher
    ..Early (P100, N170), middle (early posterior negativity; EPN), and late ERP components late positive potential were analyzed...
  44. Hagemann J, Straube T, Schulz C. Too bad: Bias for angry faces in social anxiety interferes with identity processing. Neuropsychologia. 2016;84:136-49 pubmed publisher
    ..In the learning phase, attention- and memory-associated event-related potentials (ERPs) P100, N170, P200, N250/EPN, and LPP indicated enhanced processing of angry faces, which was restricted to patients with ..
  45. Krętowski R, Borzym Kluczyk M, Stypułkowska A, Branska Januszewska J, Ostrowska H, Cechowska Pasko M. Low glucose dependent decrease of apoptosis and induction of autophagy in breast cancer MCF-7 cells. Mol Cell Biochem. 2016;417:35-47 pubmed publisher
    ..Furthermore, the MCF-7 cells incubated in the low glucose medium for 48 h showed a higher expression of NF-?B p100/p52 subunits compared to cells incubated in the high glucose medium...
  46. Liu Y, Liu P, Liu S, Guo Y, He H, Yang C, et al. Oligoadenylate synthetase 3 S381R gene polymorphism is associated with severity of EV71 infection in Chinese children. J Clin Virol. 2018;101:29-33 pubmed publisher
    Oligoadenylate synthetase 3 (OAS3) is interferon-induced antiviral enzyme, playing a significant role in the innate immune response...
  47. Méndez Balbuena I, Huidobro N, Silva M, Flores A, Trenado C, Quintanar L, et al. Effect of mechanical tactile noise on amplitude of visual evoked potentials: multisensory stochastic resonance. J Neurophysiol. 2015;114:2132-43 pubmed publisher
    ..We compared the amplitude of the positive P100 VEP component between zero noise (ZN), optimal noise (ON), and high mechanical noise (HN)...
  48. Schwarzová K, Kozub P, Szep Z, Golovchenko M, Rudenko N. Detection of Borrelia burgdorferi sensu stricto and Borrelia garinii DNAs in patient with Hyperkeratosis lenticularis perstans (Flegel disease). Folia Microbiol (Praha). 2016;61:359-63 pubmed publisher
    ..The recombinant test detected IgG antibody response against p100 and p41 antigens...
  49. Nakata H, Aoki M, Sakamoto K. Effects of mastication on human somatosensory processing: A study using somatosensory-evoked potentials. Neurosci Res. 2017;117:28-34 pubmed publisher
    ..amplitudes and latencies of P14, N20, P25, N35, P45, and N60 components at C3', frontal N30 component at Fz, and P100 and N140 components at Pz were analyzed...
  50. Jastrzebski N, Crewther S, Crewther D. Mathematical impairment associated with high-contrast abnormalities in change detection and magnocellular visual evoked response. Exp Brain Res. 2015;233:3039-46 pubmed publisher
    ..group showed an abnormal lack of contrast saturation in the shortest latency first-order peak (N60) and a delayed P100 positivity in the first slice of the second-order kernel...
  51. Lee J, Cho K, Park K, Oh S. Analysis of Retinal Layer Thicknesses and Their Clinical Correlation in Patients with Traumatic Optic Neuropathy. PLoS ONE. 2016;11:e0157388 pubmed publisher
    ..of each retinal layer and visual function parameters, including best corrected visual acuity, color vision, P100 latency, and P100 amplitude in visual evoked potential (VEP), mean deviation (MD) and visual field index (VFI) in ..
  52. Sangari S, Giron A, Marrelec G, Pradat P, Marchand Pauvert V. Abnormal cortical brain integration of somatosensory afferents in ALS. Clin Neurophysiol. 2018;129:874-884 pubmed publisher
    ..peripheral (N9) and early cortical component (N20, P25, N30) reductions, while the late cortical components (N60, P100) were more depressed than the early ones...
  53. Luckhardt C, Kröger A, Cholemkery H, Bender S, Freitag C. Neural Correlates of Explicit Versus Implicit Facial Emotion Processing in ASD. J Autism Dev Disord. 2017;47:1944-1955 pubmed publisher
    ..EEG was obtained from N?=?21 ASD and N?=?16 TDC. Task performance, visual (P100, N170) and cognitive (late positive potential) event-related-potentials, as well as coherence were compared across ..
  54. Omland P, Uglem M, Hagen K, Linde M, Tronvik E, Sand T. Visual evoked potentials in migraine: Is the "neurophysiological hallmark" concept still valid?. Clin Neurophysiol. 2016;127:810-816 pubmed publisher
    ..VEPs were recorded in six blocks of 100 single responses. Linear N70-P100 amplitude change over blocks (habituation slope) was compared with an independent samples Student's t-test...
  55. Kashyap R, Ouyang G, Sommer W, Zhou C. Neuroanatomic localization of priming effects for famous faces with latency-corrected event-related potentials. Brain Res. 2016;1632:58-72 pubmed publisher
    ..Sources for activity around P100, N170, early repetition effect (ERE/N250r) and late repetition effect (LRE/N400) were reported and priming effects ..
  56. de Oliveira K, Kaergel E, Heinig M, Fontaine J, Patone G, Muro E, et al. A roadmap of constitutive NF-?B activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses. Genome Med. 2016;8:28 pubmed publisher
    ..p50 and p52 are formed through NIK-dependent p105 and p100 precursor processing in HL cells and are the predominant DNA binding subunits...
  57. Janáky M, Jánossy Ã, Horváth G, Benedek G, Braunitzer G. VEP and PERG in patients with multiple sclerosis, with and without a history of optic neuritis. Doc Ophthalmol. 2017;134:185-193 pubmed publisher
    ..of multiple sclerosis, but the analysis mostly focuses on visual evoked potential (VEP) and especially the P100 component...
  58. Akın O, Arslan M, Akgün H, Yavuz S, Sarı E, Taşçılar M, et al. Visual and brainstem auditory evoked potentials in children with obesity. Brain Dev. 2016;38:310-6 pubmed publisher
    ..The latencies and amplitudes of VEP and BAEP were measured in healthy and obese subjects. The VEP P100, BAEP interpeak latency (IPL) I-III and IPL I-V averages of obese children were significantly longer than the ..
  59. Lin C, Tsai C. Carnosic Acid Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells by Inducing Autophagy Through an Enhanced Interaction of Parkin and Beclin1. Mol Neurobiol. 2017;54:2813-2822 pubmed publisher
    ..CA had increased protein levels of parkin and autophagy-related markers, including phosphatidylinositol 3-kinase p100, Beclin1, autophagy-related gene 7, and microtubule-associated protein 1 light chain 3-II, as well as enhanced ..
  60. Dotto P, Berezovsky A, Sacai P, Rocha D, Salomão S. Gender-based normative values for pattern-reversal and flash visually evoked potentials under binocular and monocular stimulation in healthy adults. Doc Ophthalmol. 2017;135:53-67 pubmed publisher
    ..4 ± 13.7 years; median = 40.0 years) were included. Mean P100 latencies for 15' and 60' stimuli were, respectively, 94.6 ± 4.7 ms and 96.1 ± 4.2 for women...
  61. Jimi E, Fukushima H. [NF-κB signaling pathways and the future perspectives of bone disease therapy using selective inhibitors of NF-κB]. Clin Calcium. 2016;26:298-304 pubmed publisher
    ..NF-κB consists of five members, such as p65(RelA), RelB, c-Rel, p50/p105(NF-κB1), and p52/p100(NF-κB2)...
  62. Wang X, Wang J, Liu H, Xu R, Ding R, Jiang S, et al. TRAF6 is required for BLyS-mediated NF-κB signaling in multiple myeloma cells. Med Oncol. 2015;32:239 pubmed publisher
    ..Depletion of TRAF6 by siRNA decreased levels of p-p65 and p-p100, even after stimulation with rhBLyS. Down-regulation of TRAF6 also abrogated rhBLyS-mediated cell viability...
  63. Fargier R, Laganaro M. Spatio-temporal Dynamics of Referential and Inferential Naming: Different Brain and Cognitive Operations to Lexical Selection. Brain Topogr. 2017;30:182-197 pubmed publisher
    ..ERPs waveform amplitudes and periods of stable global electrophysiological patterns differed across tasks after the P100 component and until 400-500 ms, suggesting the involvement of different, task-specific neural networks...
  64. Keil V, Uusberg A, Blechert J, Tuschen Caffier B, Schmitz J. Facial gender but not emotion distinguishes neural responses of 10- to 13-year-old children with social anxiety disorder from healthy and clinical controls. Biol Psychol. 2018;135:36-46 pubmed publisher
    ..Behavioral (reaction time and accuracy) and electrocortical measures (P100, N170, EPN, LPP) were assessed during a facial emotion identification task in children (age 10-13) with SAD (n =..
  65. Yuan S, Luo T, Liu Z, Lin Y. Efficacy of different fluids preload on propofol injection pain: A randomized, controlled, double-blinded study. J Huazhong Univ Sci Technolog Med Sci. 2016;36:249-253 pubmed publisher
    ..When fluid preload given with Plasma-Lyte A 100 mL (P100 group), 250 mL (P250 group), 500 mL (P500 group), 0...
  66. Dietrich J, Yermakov M, Reponen T, Kulkarni P, Qi C, Grinshpun S. Protection of firefighters against combustion aerosol particles: simulated workplace protection factor of a half-mask respirator (pilot study). J Occup Environ Hyg. 2015;12:415-20 pubmed publisher
    ..particles originated by combustion of different materials into elastomeric half-mask respirators equipped with two P100 filters...
  67. Hari Kumar K, Ahmad F, Sood S, Mansingh S. Visual Evoked Potential to Assess Retinopathy in Gestational Diabetes Mellitus. Can J Diabetes. 2016;40:131-4 pubmed publisher
    ..VEP was recorded in both eyes to derive prominent positive peak latency (P100), amplitude and initial negative deflection (N75) latency...
  68. Takemura M, Hori M, Yokoyama K, Hamasaki N, Suzuki M, Kamagata K, et al. Alterations of the optic pathway between unilateral and bilateral optic nerve damage in multiple sclerosis as revealed by the combined use of advanced diffusion kurtosis imaging and visual evoked potentials. Magn Reson Imaging. 2017;39:24-30 pubmed publisher
    ..On the basis of the P100 latency in VEPs, the MS patients were divided into three groups: bilateral (n=7), unilateral (n=7), and no ..
  69. Zhou L, Xu J, Zhang J, Yan C, Lin Y, Jia Y, et al. Prenatal maternal stress in relation to the effects of prenatal lead exposure on toddler cognitive development. Neurotoxicology. 2017;59:71-78 pubmed publisher
    ..maternal blood lead concentrations (log10-transformed) and toddlers' cognitive levels were observed among high (P75-P100) prenatal stress group in the domains of language (β=-33.82, 95%CI: -60.04, -7.59), social behavior (β=-41...
  70. Fiedler P, Pedrosa P, Griebel S, Fonseca C, Vaz F, Supriyanto E, et al. Novel Multipin Electrode Cap System for Dry Electroencephalography. Brain Topogr. 2015;28:647-656 pubmed publisher
    ..52 and 0.44% of the map areas for the N75 and N145 VEP components, respectively. For the P100 component, no significant differences are observed...
  71. Comabella M, Craig D, Morcillo Suarez C, Rio J, Navarro A, Fernández M, et al. Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis. Arch Neurol. 2009;66:972-8 pubmed publisher
    ..This study supports an underlying polygenic response to interferon beta treatment in MS and highlights the importance of the glutamatergic system in patient response to interferon beta therapy. ..
  72. Hildebrand S, Hultin S, Subramani A, Petropoulos S, Zhang Y, Cao X, et al. The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching. Sci Rep. 2017;7:9540 pubmed publisher
    ..In this report we show that p100 amotL2 forms a complex with E-cadherin that associates with radial actin filaments connecting cells over multiple ..
  73. Iao T, Rong S, Ling A, Brelén M, Young A, Chong K. Electrophysiological Studies in Thyroid Associated Orbitopathy: A Systematic Review. Sci Rep. 2017;7:12108 pubmed publisher
    ..Eyes of TAO patients with DON showed delayed P100 latencies, decreased P100 amplitudes or delayed N75 latencies during pVEP, compared to those without or healthy ..
  74. Pereira B, da Luz A, Lepienski C, Mazzaro I, Kuromoto N. Niobium treated by Plasma Electrolytic Oxidation with calcium and phosphorus electrolytes. J Mech Behav Biomed Mater. 2018;77:347-352 pubmed publisher
    ..Comparing the different experimental conditions, films obtained with phosphoric acid (P100) show superficial pores, phosphorus incorporation, high hydrophilicity, non-crystalline oxide formation, and good ..
  75. Quach H, Kondo T, Watanabe M, Tamura R, Yajima Y, Sayama S, et al. Eudesmane-Type Sesquiterpene Lactones Inhibit Nuclear Translocation of the Nuclear Factor ?B Subunit RelB in Response to a Lymphotoxin ? Stimulation. Biol Pharm Bull. 2017;40:1669-1677 pubmed publisher
    ..Although SRC2 did not prevent the processing of the NF-?B subunit p100 induced by LT?, it inhibited the nuclear translocation of RelB and p52 in response to the LT? stimulation...
  76. Hülsdünker T, Strüder H, Mierau A. Visual but not motor processes predict simple visuomotor reaction time of badminton players. Eur J Sport Sci. 2017;:1-11 pubmed publisher
    ..For pattern reversal stimuli, the P100 latency and age best predicted EMG onset (r?=?0.43; p =?.003) and VMRT (r?=?0.62; p?=?.001)...
  77. Barkhash A, Perelygin A, Babenko V, Myasnikova N, Pilipenko P, Romaschenko A, et al. Variability in the 2'-5'-oligoadenylate synthetase gene cluster is associated with human predisposition to tick-borne encephalitis virus-induced disease. J Infect Dis. 2010;202:1813-8 pubmed publisher
    ..Twenty-three single nucleotide polymorphisms located within the OAS1, OAS2, OAS3, and OASL genes were analyzed in 142 patients with Russian tick-borne encephalitis...
  78. Zhang J, Wu C, Meng Y, Yuan Z. Different Neural Correlates of Emotion-Label Words and Emotion-Laden Words: An ERP Study. Front Hum Neurosci. 2017;11:455 pubmed publisher
    ..Results showed that (1) emotion-label words and emotion-laden words elicited similar P100 at the posteriors sites, (2) larger N170 was found for emotion-label words than for emotion-laden words at the ..
  79. Stockdale L, Morrison R, Palumbo R, Garbarino J, Silton R. Cool, Callous, and in Control: Superior Inhibitory Control in Frequent Players of Video Games with Violent Content. Soc Cogn Affect Neurosci. 2017;: pubmed publisher
    ..Frequent players had lower levels of empathy as well as a reduction in brain activity as indicated by P100 and N200/P300 event related potentials (ERPs)...
  80. Chaaithanya I, Muruganandam N, Surya P, Anwesh M, Alagarasu K, Vijayachari P. Association of Oligoadenylate Synthetase Gene Cluster and DC-SIGN (CD209) Gene Polymorphisms with Clinical Symptoms in Chikungunya Virus Infection. DNA Cell Biol. 2016;35:44-50 pubmed publisher
    ..CD209 gene (rs735239, rs4804803, rs2287886) and OAS1 (rs1131454 and rs10774671), OAS2 (rs15895 and rs1732778), and OAS3 (rs2285932 and rs2072136) genes were investigated in 100 patients with CHIKV infection and 101 healthy controls to ..
  81. Fan H, Zhao G, Ren D, Liu F, Dong G, Hou Y. Gender differences of B cell signature related to estrogen-induced IFI44L/BAFF in systemic lupus erythematosus. Immunol Lett. 2017;181:71-78 pubmed publisher
    ..b>OAS3, RGS13, STAG3, IFI44L, STS-1, FERIL14, ZBTB16, USP18, USP41, RSAD2, FKBP5, IL1R2, DNAPTP6 and ILI27, which top 14 ..
  82. Breu D, Müller E. [Heterogeneity of canine immune responses to Borrelia burgdorferi in a line immunoassay comprising recombinant VlsE and C6 peptide]. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2017;45:295-300 pubmed publisher
    ..2% of the dogs. The bands that most frequently tested positive were p100 (24.3%), p31/OspA (18.5%), C6 (16.3%) and VlsE (13.9%). A total of 236 dogs (17...
  83. Aslibekyan S, An P, Frazier Wood A, Kabagambe E, Irvin M, Straka R, et al. Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Nutr Metab Cardiovasc Dis. 2013;23:987-94 pubmed publisher
    ..Our findings provide support for fine-mapping of the 12q24 region to investigate the shared biological mechanisms underlying levels of circulating adiponectin and susceptibility to metabolic disease. ..
  84. Li Y, Banerjee S, Wang Y, Goldstein S, Dong B, Gaughan C, et al. Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses. Proc Natl Acad Sci U S A. 2016;113:2241-6 pubmed publisher
    ..Although all three enzymatically active OAS proteins in humans--OAS1, OAS2, and OAS3--synthesize 2-5A upon binding dsRNA, it is unclear which are responsible for RNase L activation during viral ..
  85. Roy P, Mukherjee T, Chatterjee B, Vijayaragavan B, Banoth B, Basak S. Non-canonical NF?B mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB:p50 NF?B pathway. Oncogene. 2017;36:1417-1429 pubmed publisher
    ..acquire gain-of-function mutations in the non-canonical NF?B module, which induces partial proteolysis of p100 into p52 to promote RelB:p52/NF?B activation from p100-inhibited complex during immune cell differentiation...
  86. Cubo N, Garcia M, Del Cañizo J, Velasco D, Jorcano J. 3D bioprinting of functional human skin: production and in vivo analysis. Biofabrication. 2016;9:015006 pubmed
    ..We were able to generate 100 cm2, a standard P100 tissue culture plate, of printed skin in less than 35 min (including the 30 min required for fibrin gelation)...
  87. Mukherjee T, Chatterjee B, Dhar A, Bais S, Chawla M, Roy P, et al. A TNF-p100 pathway subverts noncanonical NF-κB signaling in inflamed secondary lymphoid organs. EMBO J. 2017;36:3501-3516 pubmed publisher
    ..In this pathway, NIK promotes partial proteolysis of p100 into p52 that induces nuclear translocation of the RelB NF-κB heterodimers...
  88. Wu X, Zhu X, Zhu S, Li J, Ma J, Li Z, et al. A pharmacogenetic study of polymorphisms in interferon pathway genes and response to interferon-alpha treatment in chronic hepatitis B patients. Antiviral Res. 2009;83:252-6 pubmed publisher
    ..1% vs. 8.7%, p=0.015). Our study suggested that patients with a G-T-G-A OAS haplotype were less responsive to IFNalpha treatment. ..
  89. Kwon Y, Kang J, Hwang S, Ahn B. The ribonuclease L-dependent antiviral roles of human 2',5'-oligoadenylate synthetase family members against hepatitis C virus. FEBS Lett. 2013;587:156-64 pubmed publisher
    ..Our data suggested that among the members of the OAS family, OAS1 p46 and OAS3 p100 mediate the RNase L-dependent antiviral activity against HCV.
  90. Alagarasu K, Honap T, Damle I, Mulay A, Shah P, Cecilia D. Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection. Infect Genet Evol. 2013;14:390-5 pubmed publisher
    ..Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction ..
  91. Malaguarnera L, Nunnari G, Di Rosa M. Nuclear import sequence identification in hOAS3 protein. Inflamm Res. 2016;65:895-904 pubmed
    ..b>OAS3, belonging to OASs gene family, synthesizes dimeric 2-5A that binds to RNase L with low affinity and produces 2-5A ..
  92. Chatterjee B, Banoth B, Mukherjee T, Taye N, Vijayaragavan B, Chattopadhyay S, et al. Late-phase synthesis of IκBα insulates the TLR4-activated canonical NF-κB pathway from noncanonical NF-κB signaling in macrophages. Sci Signal. 2016;9:ra120 pubmed publisher
    ..Concomitantly activated noncanonical signaling generates p52 from the p100 precursor...