NR4A3

Summary

Gene Symbol: NR4A3
Description: nuclear receptor subfamily 4 group A member 3
Alias: CHN, CSMF, MINOR, NOR1, TEC, nuclear receptor subfamily 4 group A member 3, chondrosarcoma, extraskeletal myxoid, fused to EWS, mitogen-induced nuclear orphan receptor, neuron-derived orphan receptor 1, nuclear hormone receptor NOR-1, translocated in extraskeletal chondrosarcoma
Species: human
Products:     NR4A3

Top Publications

  1. Ohkura N, Ito M, Tsukada T, Sasaki K, Yamaguchi K, Miki K. Structure, mapping and expression of a human NOR-1 gene, the third member of the Nur77/NGFI-B family. Biochim Biophys Acta. 1996;1308:205-14 pubmed
    ..This suggests that the Nur77/NGFI-B family has evolved from a common ancestral gene. Fluorescence in situ hybridization (FISH) revealed that the gene is located on chromosome 9q. ..
  2. Pei L, Castrillo A, Chen M, Hoffmann A, Tontonoz P. Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli. J Biol Chem. 2005;280:29256-62 pubmed
    ..cytokines, or oxidized lipids triggers the transcriptional induction of Nur77 (NR4A1), Nurr1 (NR4A2), and NOR1 (NR4A3) expression...
  3. Pearen M, Myers S, Raichur S, Ryall J, Lynch G, Muscat G. The orphan nuclear receptor, NOR-1, a target of beta-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle. Endocrinology. 2008;149:2853-65 pubmed publisher
    ..In conclusion, NOR-1 is necessary for oxidative metabolism in skeletal muscle. ..
  4. Sjogren H, Wedell B, Meis Kindblom J, Kindblom L, Stenman G, Kindblom J. Fusion of the NH2-terminal domain of the basic helix-loop-helix protein TCF12 to TEC in extraskeletal myxoid chondrosarcoma with translocation t(9;15)(q22;q21). Cancer Res. 2000;60:6832-5 pubmed
    ..translocations resulting in fusions of the NH2-terminal transactivation domains of EWS or TAF2N to the entire TEC protein...
  5. Noguchi H, Mitsuhashi T, Seki K, Tochigi N, Tsuji M, Shimoda T, et al. Fluorescence in situ hybridization analysis of extraskeletal myxoid chondrosarcomas using EWSR1 and NR4A3 probes. Hum Pathol. 2010;41:336-42 pubmed publisher
    ..and the resultant fused gene, Ewing sarcoma region 1-nuclear receptor subfamily 4, group A, member 3 (EWSR1-NR4A3)...
  6. Pacak K. Phaeochromocytoma: a catecholamine and oxidative stress disorder. Endocr Regul. 2011;45:65-90 pubmed
    ..Dopamine is a minor component, but some paragangliomas produce only this catecholamine or this together with norepinephrine...
  7. Yildirim A, Karakaş F, Turker A. In vitro antibacterial and antitumor activities of some medicinal plant extracts, growing in Turkey. Asian Pac J Trop Med. 2013;6:616-24 pubmed publisher
    ..annua) L., Genista lydia (G. lydia) Boiss., Nuphar lutea (N. lutea) L., Nymphaea alba (N. alba) L., Vinca minor (V. minor) L., Stellaria media (S. media) L., Capsella bursa-pastoris (C. bursa-pastoris) L., Galium spurium (G...
  8. Atmaca O, Zarakolu P, Karahan C, Cakır B, Unal S. [Risk factors and antibiotic use in methicillin-resistant Staphylococcus aureus bacteremia in hospitalized patients at Hacettepe University Adult and Oncology Hospitals (2004-2011) and antimicrobial susceptibilities of the isolates: a nested case-con. Mikrobiyol Bul. 2014;48:523-37 pubmed
    ..piperacillin-tazobactam (TZP), meropenem (MEM), imipenem (IPM), vancomycin (VAN), cephalosporins and teicoplanin (TEC)] were found to be statistically significantly higher in the case group by univariate analysis (p< 0.05)...
  9. Oksanen A, Siles Lucas M, Karamon J, Possenti A, Conraths F, Romig T, et al. The geographical distribution and prevalence of Echinococcus multilocularis in animals in the European Union and adjacent countries: a systematic review and meta-analysis. Parasit Vectors. 2016;9:519 pubmed
    ..Muskrats and arvicolids are important IHs. Swine, insectivores, murids and nutrias seem to play a minor or no role in the life-cycle of the parasite within the EU and ACs.

More Information

Publications145 found, 100 shown here

  1. Mercier Darty M, Boutolleau D, Lepeule R, Rodriguez C, Burrel S. Utility of ultra-deep sequencing for detection of varicella-zoster virus antiviral resistance mutations. Antiviral Res. 2018;151:20-23 pubmed publisher
    ..2016; Piret and Boivin, 2014). However, this approach cannot detect minor variants present at a frequency below 20%...
  2. Dutkiewicz J, Sroka J, Zajac V, Wasiński B, Cisak E, Sawczyn A, et al. Streptococcus suis: a re-emerging pathogen associated with occupational exposure to pigs or pork products. Part I - Epidemiology. Ann Agric Environ Med. 2017;24:683-695 pubmed publisher
    ..Bacteria are transmitted to workers by close contact with pigs or pig products, usually through contamination of minor cuts or abrasions on skin of hands and/or arms, or by pig bite...
  3. Xiao Y, Wei Z, Shen P, Ji J, Sun Z, Yu H, et al. Bacterial-resistance among outpatients of county hospitals in China: significant geographic distinctions and minor differences between central cities. Microbes Infect. 2015;17:417-25 pubmed publisher
  4. Bakić M, Ratkovic M, Gledovic B, Vujovic B, Radunovic D, Babić V, et al. Cutaneous Manifestations of Tuberous Sclerosis. Acta Dermatovenerol Croat. 2018;26:73-74 pubmed
    ..present on the skin of the trunk and on the upper and lower extremities (Figure 2), accompanied by surrounding minor changes in the form of confetti-like maculae...
  5. Rohde U. EndoBarrier gastrointestinal liner. Delineation of underlying mechanisms and clinical effects. Dan Med J. 2016;63: pubmed
    ..GLP-1 and PYY concentrations increased in patients with T2D (not NGT subjects) after implantation. DJBS had no or minor effects on postprandial levels of glucose, insulin, C-peptide, glucagon, GIP, CCK or gastrin...
  6. Norrman E, Bergh C, Wennerholm U. Pregnancy outcome and long-term follow-up after in vitro fertilization in women with renal transplantation. Hum Reprod. 2015;30:205-13 pubmed publisher
    ..3%) had very low birthweight (VLBW) (672 g) and one (14.3%) was small for gestational age (SGA). Two infants had minor birth defects. One woman developed pre-eclampsia (14.3%). Mean age at follow-up of the children was 9...
  7. Field F, Wallington T, Everson M, Kirchain R. Strategic materials in the automobile: A comprehensive assessment of strategic and minor metals use in passenger cars and light trucks. Environ Sci Technol. 2017;: pubmed publisher
    A comprehensive component-level assessment of several strategic and minor metals (SaMMs) including copper, manganese, magnesium, nickel, tin, niobium, light rare earth elements (lanthanum, cerium, praseodymium, neodymium, promethium, and ..
  8. Wang L. Engineering the Genetic Code in Cells and Animals: Biological Considerations and Impacts. Acc Chem Res. 2017;50:2767-2775 pubmed publisher
    ..Genome integration of the orthogonal tRNA/aaRS in mice results in minor changes in RNA transcripts but no significant physiological impairment. Lastly, the RF1 knockout E...
  9. Leligdowicz A, Fischer W, Uyeki T, Fletcher T, Adhikari N, Portella G, et al. Ebola virus disease and critical illness. Crit Care. 2016;20:217 pubmed publisher
    ..Although minor bleeding manifestations are common, hypovolemic and septic shock complicated by multisystem organ dysfunction ..
  10. Jean P, Sloter E, Plotzke K. Effects of chronic exposure to octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane in the aging female Fischer 344 rat. Toxicol Lett. 2017;279 Suppl 1:54-74 pubmed publisher
    ..D4 and D5 may remain as residual monomer in these polymers at less than 1000ppm and may therefore be present as a minor impurity in consumer products...
  11. Castaño A, Cutanda F, Esteban M, Pärt P, Navarro C, Gómez S, et al. Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries. Environ Res. 2015;141:58-68 pubmed publisher
    ..Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort...
  12. Senat M, Sentilhes L, Battut A, Benhamou D, Bydlowski S, Chantry A, et al. Postpartum practice: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF). Eur J Obstet Gynecol Reprod Biol. 2016;202:1-8 pubmed publisher
    ..professional consensus) with or without the addition of LMWH, depending on the presence and severity (major or minor) of additional risk factors...
  13. Bulatova I, Shchekotova A, Krivtsov A, Shchekotov V, Nasibullina N, Suzdal tseva K, et al. [Metabolic disorder and polymorphism of the genes encoding for beta-2-adrenergic receptor and apolipoproteins B in chronic hepatitis C and non-alcoholic fatty liver diseases]. Klin Med (Mosk). 2015;93:35-41 pubmed
    ..Patients with CHC showed an increased frequency of minor A allele of the ADRB2 (rs1042713) gene (up to 40%; p=0.04) and pathological A/A homozygote (22%; p=0.04)...
  14. Sénat M, Sentilhes L, Battut A, Benhamou D, Bydlowski S, Chantry A, et al. [Post-partum: Guidelines for clinical practice--Short text]. J Gynecol Obstet Biol Reprod (Paris). 2015;44:1157-66 pubmed publisher
    ..of LMWH according to the presence or not of additional risk factors, and depending on the risk factor (major, minor). Early postoperative rehabilitation is encouraged (Professional consensus)...
  15. Negreş S, Zanfirescu A, Ionică F, Moroşan E, Velescu B, Şeremet O, et al. Pharmacotoxicological screening on new derivatives of beta-phenylethylamine, potential agonists of beta3-adrenergic receptors. Rom J Morphol Embryol. 2016;57:969-978 pubmed
    ..C2 was also the compound to favorably modify the dynamics of determined enzymes, together with the display of very good safety profile supported by minor, non-significant, histopathological changes.
  16. Ko J, Sun Y, Li W, Wang F. Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis. J Mol Med (Berl). 2016;94:755-69 pubmed publisher
    ..2-deoxyglucose-probed fluorescence imaging, and μCT revealed that affected knees of TgHSP60 mice showed minor footprint irregularity, joint inflammation, and osteophyte formation...
  17. Altinoz M, Ince B. Hemoglobins emerging roles in mental disorders. Metabolical, genetical and immunological aspects. Int J Dev Neurosci. 2017;61:73-85 pubmed publisher
    ..We demonstrated a protective role of minor HbA2 against post-partum episodes in BD and association of higher minor HbF (fetal hemoglobin) levels with family ..
  18. Lowings M, Ehlers M, Dreyer A, Kock M. High prevalence of oxacillinases in clinical multidrug-resistant Acinetobacter baumannii isolates from the Tshwane region, South Africa - an update. BMC Infect Dis. 2015;15:521 pubmed publisher
    ..isolates from the four major pulsotypes (≥5 isolates with 80 % similarity) and selective isolates from each minor pulsotype. All the A...
  19. Nohuz E, Gallot D, Rousset C, Brunel A, Albaut M, Bayeh S, et al. [Congenital mucocele of the ventral face of the tongue]. Arch Pediatr. 2016;23:287-91 pubmed publisher
    ..tongue are very rare benign lesions of the oral cavity, resulting from extravasation or retention of mucus from minor salivary glands...
  20. Kobayashi H, Kikuta K, Sekita T, Susa M, Nishimoto K, Sasaki A, et al. Diagnosis of extraskeletal myxoid chondrosarcoma in the thigh using EWSR1-NR4A3 gene fusion: a case report. J Med Case Rep. 2016;10:321 pubmed
    ..Nevertheless, extraskeletal myxoid chondrosarcoma has a rare gene fusion (EWSR1-NR4A3) that is useful for making a differential diagnosis...
  21. Barthold J, Pugarelli J, Macdonald M, Ren J, Adetunji M, Polson S, et al. Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat. Mol Hum Reprod. 2016;22:18-34 pubmed publisher
    ..Cryptorchidism in the LE/orl rat is associated with a unique combination of homozygous minor alleles at multiple loci, and the encoded proteins are co-localized with androgen receptor (AR) and Leydig cells ..
  22. Torres Odio S, Key J, Hoepken H, Canet Pons J, Valek L, Roller B, et al. Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. J Neuroinflammation. 2017;14:154 pubmed publisher
    ..factors appeared, together with profiles of bacterial invasion and MAPK signaling changes-while mitophagy had minor significance...
  23. Kuon R, Abele H, Berger R, Garnier Y, Maul H, Schleußner E, et al. [Progesterone for Prevention of Preterm Birth--Evidence-based Indications]. Z Geburtshilfe Neonatol. 2015;219:125-35 pubmed publisher
    ..VI) The vaginal administration of progesterone is well-tolerated by the patients and has only minor maternal side effects, whereas intramuscular injections of 17-OHPC are associated with a significant higher rate ..
  24. Matanes E, Weissman A, Rivlin A, Lauterbach R, Amit A, Wiener Z, et al. Effects of Pneumoperitoneum and the Steep Trendelenburg Position on Heart Rate Variability and Cerebral Oxygenation during Robotic Sacrocolpopexy. J Minim Invasive Gynecol. 2018;25:70-75 pubmed publisher
    ..cSO2 at baseline was 73%?±?9%, with minor and insignificant elevation during the operation...
  25. Defazio M, Han K, Akbari C, Evans K. Free tissue transfer after targeted endovascular reperfusion for complex lower extremity reconstruction: setting the stage for success in the presence of mutlivessel disease. Ann Vasc Surg. 2015;29:1316.e7-1316.e15 pubmed publisher
    ..7 months. Minor flap necrosis, necessitating debridement and skin grafting, was seen in one patient, who ultimately required a ..
  26. He S, Tong X, Han M, Hu H, Dai F. Genome-Wide Identification and Characterization of WD40 Protein Genes in the Silkworm, Bombyx mori. Int J Mol Sci. 2018;19: pubmed publisher
    ..Sequence analyses indicated that tandem and segmental duplication played minor roles in producing the current number of BmWD40s, and domain recombination events of multi-domain ..
  27. Ochiai S, Nomoto Y, Yamashita Y, Murashima S, Hasegawa D, Kurobe Y, et al. Radiation-induced organizing pneumonia after stereotactic body radiotherapy for lung tumor. J Radiat Res. 2015;56:904-11 pubmed publisher
    ..Three patients with minor symptoms were managed without corticosteroid administration and OP resolved without any relapse...
  28. Friedman E, Texeira L, Delaney J, Weeke P, Lynch D, Kasasbeh E, et al. Evaluation of the F2R IVS-14A/T PAR1 polymorphism with subsequent cardiovascular events and bleeding in patients who have undergone percutaneous coronary intervention. J Thromb Thrombolysis. 2016;41:656-62 pubmed publisher
    ..The minor allele (T) frequency was 14.8 %. There were no genotypic differences in the frequency of MACE (33.7, 28.8, and 31...
  29. Palau J, Jamin P, Badin A, Vanhecke N, Haerens B, Brouyère S, et al. Use of dual carbon-chlorine isotope analysis to assess the degradation pathways of 1,1,1-trichloroethane in groundwater. Water Res. 2016;92:235-43 pubmed publisher
    ..The observed deviation could be explained by a minor contribution of additional degradation processes...
  30. Viquez O, Yazlovitskaya E, Tu T, Mernaugh G, Secades P, McKee K, et al. Integrin alpha6 maintains the structural integrity of the kidney collecting system. Matrix Biol. 2017;57-58:244-257 pubmed publisher
    ..Integrin α3β1, one of the major laminin receptors, plays a minor role in kidney collecting system development, while the role of α6 containing integrins (α6β1 and α6Î..
  31. Nakayama I, Shinozaki E, Matsushima T, Wakatsuki T, Ogura M, Ichimura T, et al. Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients. BMC Cancer. 2017;17:38 pubmed publisher
    After analysis of minor RAS mutations (KRAS exon 3, 4/NRAS) in the FIRE-3 and PRIME studies, an expanded range of RAS mutations were established as a negative predictive marker for the efficacy of anti-EGFR antibody treatment...
  32. Biato E, Costa L, Monteiro S. Minor and major health: a Nietzschean reading. Cien Saude Colet. 2017;22:965-974 pubmed publisher
    ..use Friedrich Nietzsche's philosophical thought as an analytical tool, allowing us to reach a typology involving minor and major health...
  33. Gómez Chabala L, Cuartas C, López M. Release Behavior and Antibacterial Activity of Chitosan/Alginate Blends with Aloe vera and Silver Nanoparticles. Mar Drugs. 2017;15: pubmed publisher
    ..matrices with Aloe vera (AV) gel and silver nanoparticles (AgNps) described here displayed antibacterial properties and absorption and Aloe vera release capacity making it a potential wound dressing for minor injuries.
  34. Barakat A, Al Majid A, Al Qahtany B, Ali M, Teleb M, Al Agamy M, et al. Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole-dimedone hybrid architectures. Chem Cent J. 2018;12:29 pubmed publisher
    ..were assigned based on different spectroscopic techniques (1H-NMR, 13C-NMR, IR, MS, and CHN). The synthesized compounds were evaluated for their antibacterial and antifungal activities against S...
  35. Araszkiewicz M, Łopatkiewicz A, Zienkiewicz A, Zurek T. Framing a Knowledge Base for a Legal Expert System Dealing with Indeterminate Concepts. ScientificWorldJournal. 2015;2015:985425 pubmed publisher
    ..or PPSS) to support parents in drafting an agreement (the parenting plan) for the exercise of parental custody of minor children after a divorce is granted...
  36. Wiltberger G, Bucher J, Krenzien F, Benzing C, Atanasov G, Schmelzle M, et al. Extended resection in pancreatic metastases: feasibility, frequency, and long-term outcome: a retrospective analysis. BMC Surg. 2015;15:126 pubmed publisher
    ..The median time between primary malignancy resection to metastasectomy was 83 months (range, 0-228 months). Minor surgical complications (Grade I-IIIa) occurred in six patients (33...
  37. Mekonnen A, Abebe T, McLachlan A, Brien J. Impact of electronic medication reconciliation interventions on medication discrepancies at hospital transitions: a systematic review and meta-analysis. BMC Med Inform Decis Mak. 2016;16:112 pubmed publisher
    ..was evaluated in five studies, and there was no potentially fatal error identified and most errors were minor in severity...
  38. Mubarak W, Pastor C, Gnannt R, Parra D, Amaral J, Temple M, et al. Technique, Safety, and Yield of Bone Biopsies for Histomorphometry in Children. J Vasc Interv Radiol. 2017;28:1577-1583 pubmed publisher
    ..Of 79 biopsies, 75 (95%) were uneventful. Unplanned overnight observation was required in 3 (minor SIR grade B), and prolonged hospital stay owing to hematoma causing nerve compression pain was required in 1 (..
  39. Lupolova N, Dallman T, Matthews L, Bono J, Gally D. Support vector machine applied to predict the zoonotic potential of E. coli O157 cattle isolates. Proc Natl Acad Sci U S A. 2016;113:11312-11317 pubmed
    ..Notably, only a minor subset (less than 10%) of bovine E...
  40. Li X, Gan Z, Ding Z, Wu Y, Chen X, Tian H, et al. Genetic Variants in the ELOVL5 but not ELOVL2 Gene Associated with Polyunsaturated Fatty Acids in Han Chinese Breast Milk. Biomed Environ Sci. 2017;30:64-67 pubmed publisher
    ..Two hundred and nine healthy Han Chinese mothers were included in the study. Carriers of minor alleles of SNPs (rs2397142 and rs9357760) in ELOVL5 were associated with higher levels of linoleic acid (LA), ..
  41. Oliveira S, Gomides A, Mota L, Lima C, Rocha F. Intestinal parasites infection: protective effect in rheumatoid arthritis?. Rev Bras Reumatol Engl Ed. 2017;57:461-465 pubmed publisher
    ..An apparent minor severity of RA in patients from regions with lower income could be associated with a higher prevalence of gut ..
  42. Sultan A, Bhat M, Khursheed O, Maqbool Wani M, Ahmad Kawoosa A, Kotwal H, et al. Evaluation of Complications from Stainless-Steel Flexible Intramedullary Nailing in Children's Femoral Shaft Fractures and Recommendations for Continued Use. Ortop Traumatol Rehabil. 2017;19:263-271 pubmed
    ..b]Results.[/b] All fractures united in a mean time of 9.2 weeks. Minor complications were noted in 19 patients, and major complications were noted in two patients...
  43. Eriksson S, Borsiin H, Öberg C, Brange H, Mijovic Z, Sturesson C. Perioperative liver and spleen elastography in patients without chronic liver disease. World J Gastrointest Surg. 2018;10:21-27 pubmed publisher
    ..24-1.63) m/s to 2.20 (1.72-2.44) m/s (P = 0.001). No change in liver stiffness in patients undergoing a minor resection was found [1.31 (1.15-1.52) m/s vs 1.37 (1.12-1.77) m/s, P = 0.438]...
  44. Bochatay L, Beney J, Jordan von Gunten V, Petignat P, Roulet L. [Appropriateness of the prescriptions of conventional versus new oral anticoagulants at discharge from a department of internal medicine]. Rev Med Interne. 2016;37:579-86 pubmed publisher
    ..The majority of patients receiving an ODA for an AF had a minor bleeding risk...
  45. Regina Silva S, Feres A, França Silva J, Dias E, Michalsky Ã, de Andrade H, et al. Field randomized trial to evaluate the efficacy of the Leish-Tec® vaccine against canine visceral leishmaniasis in an endemic area of Brazil. Vaccine. 2016;34:2233-9 pubmed publisher
    ..Leish-Tec(®) is a recombinant vaccine, based on the Leishmania A2 antigen, against canine VL (CVL)...
  46. Spalgais S, Agarwal U, Sarin R, Chauhan D, Yadav A, Jaiswal A. Role of routine abdominal ultrasonography in intensified tuberculosis case finding algorithms at HIV clinics in high TB burden settings. BMC Infect Dis. 2017;17:351 pubmed publisher
    ..presence of two major USG (abdomen) findings suggestive of active TB, or one major USG finding with at least two minor USG findings or at least two symptoms, or any USG finding with microbiologically confirmed active TB at another ..
  47. Rodrigues P, Ribeiro A, Perrod C, Landry J, Araújo L, Pereira Castro I, et al. Thymic epithelial cells require p53 to support their long-term function in thymopoiesis in mice. Blood. 2017;130:478-488 pubmed publisher
    ..the thymus declines with age, it is of fundamental and clinical relevance to decipher new determinants that control TEC homeostasis in vivo...
  48. Ricciardi E, Tomao F, Aletti G, Bazzurini L, Bocciolone L, Boveri S, et al. Risk-reducing Salpingo-Oophorectomy in Women at Higher Risk of Ovarian and Breast Cancer: A Single Institution Prospective Series. Anticancer Res. 2017;37:5241-5248 pubmed
    ..The aim of this study was to evaluate the incidence of tubal minor epithelial atypia (STIL), STIC, and occult invasive cancer and to evaluate the cancer-specific mortality in a ..
  49. Bertels F, Marzel A, Leventhal G, Mitov V, Fellay J, Gunthard H, et al. Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T Cell Decline and Per-Parasite Pathogenicity. Mol Biol Evol. 2017;: pubmed publisher
    ..Our analysis shows that the viral genetype affects virulence mainly by modulating the per-parasite pathogenicity, while the indirect effect via the set-point viral load is minor.
  50. van der Slikke R, Mason B, Berger M, Goosey Tolfrey V. Speed profiles in wheelchair court sports; comparison of two methods for measuring wheelchair mobility performance. J Biomech. 2017;65:221-225 pubmed publisher
    ..differences in sampling frequency and sensor location (reference point) on the wheelchair (for speed calculation), minor differences were revealed at low speeds (<2.5?m/s)...
  51. Zhang T, Maclean J, Szczesniak M, Bertrand P, Quon H, Tsang R, et al. Esophageal Dysmotility in Patients following Total Laryngectomy. Otolaryngol Head Neck Surg. 2017;:194599817736507 pubmed publisher
    ..achalasia, esophagogastric junction outflow obstruction, diffuse esophageal spasm, and other major (30%) and minor (50%) peristaltic disorders...
  52. Walser J, Ferguson S. Oriented nanofibrous membranes for tissue engineering applications: Electrospinning with secondary field control. J Mech Behav Biomed Mater. 2016;58:188-198 pubmed publisher
    ..Mean main fibre direction was 87±18°, relative to the deflection axis, while fibre alignment had only a minor effect on the average fibre diameter...
  53. Jiménez Jiménez F, Alonso Navarro H, García Martín E, Agúndez J. SLC1A2 rs3794087 variant and risk for essential tremor: a systematic review and meta-analysis. Pharmacogenet Genomics. 2015;25:564-8 pubmed publisher
    ..96 (0.74-1.23). The separate analysis in White and Asiatic individuals on the frequency of the minor allele of rs3794087 did not show significant differences between ET patients and controls in both subgroups after ..
  54. Kimura Y, Toyofuku Y, Koike S, Shibuya N, Nagahara N, Lefer D, et al. Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain. Sci Rep. 2015;5:14774 pubmed publisher
    ..H2S3 was also produced from H2S by 3MST and rhodanese. H2S2 was identified as a minor H2Sn, and 3 MP did not affect the H2S5 level...
  55. Mukherjee T, Kumar D, Burriss N, Xie Z, Alexandre G. Azospirillum brasilense Chemotaxis Depends on Two Signaling Pathways Regulating Distinct Motility Parameters. J Bacteriol. 2016;198:1764-1772 pubmed publisher
    ..The Che1 chemotaxis pathway was previously shown to regulate changes in the swimming speed, but it has a minor role in chemotaxis and root surface colonization...
  56. Lipps D, Sachdev S, Strauss J. Quantifying radiation dose delivered to individual shoulder muscles during breast radiotherapy. Radiother Oncol. 2017;122:431-436 pubmed publisher
    ..001). The pectoralis major and minor had the greatest V48 doses across the five treatments regimens...
  57. Vansteelant W, Kekkonen J, Byholm P. Wind conditions and geography shape the first outbound migration of juvenile honey buzzards and their distribution across sub-Saharan Africa. Proc Biol Sci. 2017;284: pubmed publisher
    ..were strongly affected by zonal wind speed, and negatively affected by latitudinal wind, with significant but minor differences between individuals...
  58. Dozier M, Porter B, Ayers C. Age of onset and progression of hoarding symptoms in older adults with hoarding disorder. Aging Ment Health. 2016;20:736-42 pubmed publisher
    ..discarding, and clutter) was operationalized as the first decade in which the participant reported at least minor symptom severity, and age of onset for possible HD diagnosis was operationalized as the first decade in which the ..
  59. Yang H, Wang Q, Zheng L, Lin M, Zheng X, Lin F, et al. Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent. PLoS ONE. 2015;10:e0132034 pubmed publisher
    ..Breastfeeding and the presence of the minor A allele of rs4148323 (UGTA*6) were correlated with an increased risk of hyperbilirubinemia (OR=2.17, P=0...
  60. McDonald M, Au N, Rettie A. P450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory Mechanisms. Drug Metab Dispos. 2015;43:1661-9 pubmed publisher
    ..Based on these values, the minor metabolite N,N-didesethylamiodarone (DDEA) is predicted to be the major cause of DDIs with xenobiotics primarily ..
  61. Winterbourn C. Revisiting the reactions of superoxide with glutathione and other thiols. Arch Biochem Biophys. 2016;595:68-71 pubmed publisher
    ..As shown by Sies and colleagues, singlet oxygen is a by-product. Although removal of superoxide by GSH may be a minor pathway, GSH and superoxide have a strong physiological connection...
  62. Rawal C, Riccardo S, Pesenti C, Ferrari M, Marini F, Pellicioli A. Reduced kinase activity of polo kinase Cdc5 affects chromosome stability and DNA damage response in S. cerevisiae. Cell Cycle. 2016;15:2906-2919 pubmed
    ..substitution in the T-loop reduces the kinase activity of Cdc5, the only PLK in Saccharomyces cerevisiae, with minor effect on cell growth in unperturbed conditions...
  63. Guerrieri M, Ortenzi M, Lezoche G, Mancini S, Ghiselli R. Transanal endoscopic microsurgery in the treatment of large rectal adenomas. Minerva Chir. 2016;71:360-364 pubmed
    ..Median operative time was 57 minutes (42-90 minutes). We observed 17 (8.2%) minor complications and 2 (0.9%) major complication according to the Clavien-Dindo classification...
  64. Goel A, Badran K, Braun A, Garrett A, Long J. Minor Salivary Gland Carcinoma of the Oropharynx: A Population-Based Analysis of 1426 Patients. Otolaryngol Head Neck Surg. 2017;:194599817735309 pubmed publisher
    Objective We sought to describe the patient, tumor, and survival characteristics of minor salivary gland carcinoma (MSGC) of the oropharynx using a large, population-based database...
  65. Qiao C, Zhang J, Ma X, Liu W, Liu Q. Effect of salt on the coil-helix transition of gelatin at early stages: Optical rotation, rheology and DSC studies. Int J Biol Macromol. 2018;107:1074-1079 pubmed publisher
    ..This result indicates that salt additions mainly affect the nucleation of triple helices, but had minor effect on its growth...
  66. Ganz R, Leunig M. Morphological variations of residual hip dysplasia in the adult. Hip Int. 2007;17 Suppl 5:S22-8 pubmed
    ..Finally, minor morphological abnormalities of the antero-lateral head-neck junction have been found to favor impingement after ..
  67. Uchikawa Y, Mori K, Shiigai M, Konishi T, Hoshiai S, Ishigro T, et al. Double Coaxial Microcatheter Technique for Glue Embolization of Renal Arteriovenous Malformations. Cardiovasc Intervent Radiol. 2015;38:1277-83 pubmed publisher
    ..As a minor complication, glue migrated into the venous system in four patients without any sequelae...
  68. Fuhrmann R, Pillukat T. [Subtalar arthrodesis]. Oper Orthop Traumatol. 2016;28:177-92 pubmed publisher
    ..Sensory disturbances in 8 patients; minor ankle flexion limitations. Full bone healing in 36 subtalar joints, pseudarthrosis in 4 patients.
  69. Rijkers M, van der Meer P, Bontekoe I, Daal B, de Korte D, Leebeek F, et al. Evaluation of the role of the GPIb-IX-V receptor complex in development of the platelet storage lesion. Vox Sang. 2016;111:247-256 pubmed publisher
    ..Storage time of PCs in blood banks is limited to 7 days. During this time period, a minor but gradually increasing subpopulation of GPIb?-negative platelets was observed...
  70. Cifuentes T, Cayupi J, Celis Barros C, Zapata Torres G, Ballesteros R, Ballesteros Garrido R, et al. Spectroscopic studies of the interaction of 3-(2-thienyl)-[1,2,3]triazolo[1,5-a]pyridine with 2,6-dimethyl-β-cyclodextrin and ctDNA. Org Biomol Chem. 2016;14:9760-9767 pubmed
    ..process was primarily driven by hydrophobic forces indicating that TTP interacts with ctDNA by means of the minor groove...
  71. Leavens E, Driskill L, Molina N, Eissenberg T, Shihadeh A, Brett E, et al. Comparison of a preferred versus non-preferred waterpipe tobacco flavour: subjective experience, smoking behaviour and toxicant exposure. Tob Control. 2017;: pubmed publisher
    ..The pattern of results suggests that even this relatively minor manipulation resulted in significant changes in subjective experience...
  72. Pfeil M, Yersin B, Trueb L, Feiner A, Carron P. A retrospective study of complaint letters sent to a Swiss Emergency Department between 2009 and 2014. Rev Epidemiol Sante Publique. 2018;66:75-80 pubmed publisher
    ..The consequences of 73.5% of the events in question were considered minor or negligible, 19% moderate, and 6.5% major...
  73. Santalova E, Denisenko V, Dmitrenok P. Structural Analysis of the Minor Cerebrosides from a Glass Sponge Aulosaccus sp. Lipids. 2015;50:1209-18 pubmed publisher
    The minor cerebrosides from a Far-Eastern glass sponge Aulosaccus sp. were analyzed as constituents of some multi-component RP-HPLC fractions...
  74. Lin S, Hameed A, Liu Y, Hsu Y, Hung M, Lai W, et al. Ruficoccus amylovorans gen. nov., sp. nov., an amylolytic and nitrate-reducing diazotroph of the family Puniceicoccaceae. Int J Syst Evol Microbiol. 2017;67:956-962 pubmed publisher
    ..The polyamine pattern showed a predominance of spermidine and a minor amount of cadaverine. The DNA G+C content was 57.4?mol% and the predominant quinone system was menaquinone-7...
  75. Rocha L, Pessoa C, Neto A, do Prado R, Silva E, de Almeida M, et al. Thromboelastometry versus standard coagulation tests versus restrictive protocol to guide blood transfusion prior to central venous catheterization in cirrhosis: study protocol for a randomized controlled trial. Trials. 2017;18:85 pubmed publisher
    ..the procedure; intensive care unit and hospital length of stay; 28-day and hospital mortality; incidence of minor bleeding; transfusion-related adverse reactions; and cost analysis...
  76. Lee D, Kim J, Lee J, Lim S. Sclerosing mucoepidermoid carcinoma of the sublingual gland. Eur Ann Otorhinolaryngol Head Neck Dis. 2017;134:355-356 pubmed publisher
    ..mucoepidermoid carcinoma of the salivary glands is the parotid gland, followed by the submandibular gland, and the minor salivary glands. Here we report the first case of sclerosing mucoepidermoid carcinoma of the sublingual gland...
  77. Gu J, Shin D, Pletneva E. Remote Perturbations in Tertiary Contacts Trigger Ligation of Lysine to the Heme Iron in Cytochrome c. Biochemistry. 2017;56:2950-2966 pubmed publisher
    ..A minor change in the tertiary contacts in T49V, away from the heme coordination loop, appears to be sufficient to execute ..
  78. Chen M, Zeng G, Lai C, Zhang C, Xu P, Yan M, et al. Interactions of carbon nanotubes and/or graphene with manganese peroxidase during biodegradation of endocrine disruptors and triclosan. Chemosphere. 2017;184:127-136 pubmed publisher
    ..SWCNT or SWCNT+GRA generally had a minor impact on the mean binding energy between MnP and its substrates...
  79. Maxian O, Neufeld A, Talis E, Childs L, Blackwood J. Zika virus dynamics: When does sexual transmission matter?. Epidemics. 2017;21:48-55 pubmed publisher
    ..8% contribution of sexual transmission to the basic reproductive number, R0. This contribution is too minor to independently sustain an outbreak but suggests that vector transmission is the main driver of the ongoing ..
  80. Molchanov S, Gryff Keller A. Solvation of Amides in DMSO and CDCl3; an Attempt at Quantitative DFT-Based Interpretation of 1H and 13C NMR Chemical Shifts. J Phys Chem A. 2017;: pubmed publisher
    ..At the same time, association of the amides seems to be of minor importance in DMSO, while their N-H hydrogens form strong hydrogen bonds with solvent molecules.
  81. Campino S, Auburn S, Kivinen K, Zongo I, Ouedraogo J, Mangano V, et al. Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. PLoS ONE. 2011;6:e20251 pubmed publisher
    ..mixtures of laboratory clones demonstrated high genotype calling specificity and moderate sensitivity to call minor frequency alleles...
  82. Elmer Dixon M, Bowler B. Site A-Mediated Partial Unfolding of Cytochrome c on Cardiolipin Vesicles Is Species-Dependent and Does Not Require Lys72. Biochemistry. 2017;56:4830-4839 pubmed publisher
    ..For both human and yeast cytochrome c, the K72A mutation has only minor effects on binding to site A, suggesting that other nearby lysines can compensate for the lack of Lys72.
  83. Parthier D, Kuner T, Körber C. The presynaptic scaffolding protein Piccolo organizes the readily releasable pool at the calyx of Held. J Physiol. 2017;: pubmed publisher
    ..However, short-term depression (STD) was prominently increased by the KD of Bassoon while KD of Piccolo only had a minor effect...
  84. Liu D, Jia H, Holmes D, Stannard A, Zachary I. Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1. Arterioscler Thromb Vasc Biol. 2003;23:2002-7 pubmed
    ..The most strongly induced genes were the NR4A nuclear receptor family members Nur77, Nurr1, and Nor1 and the zinc-finger transcription factor Egr3...
  85. Harita Y. Application of next-generation sequencing technology to diagnosis and treatment of focal segmental glomerulosclerosis. Clin Exp Nephrol. 2018;22:491-500 pubmed publisher
    ..genes, mutations with complex inheritance, and susceptibility genes with variable penetrance carrying relatively minor but significant effects...
  86. Dutta D, Shin K, Rainey J, Fliegel L. Transmembrane Segment XI of the Na+/H+ Antiporter of S. pombe is a Critical Part of the Ion Translocation Pore. Sci Rep. 2017;7:12793 pubmed publisher
    ..pombe. Mutation of seven other amino acids had minor effects...
  87. Kahles F, Meyer C, Diebold S, Foldenauer A, Stohr R, Möllmann J, et al. Glucose-dependent insulinotropic peptide secretion is induced by inflammatory stimuli in an interleukin-1-dependent manner in mice. Diabetes Obes Metab. 2016;18:1147-1151 pubmed publisher
    ..In conclusion, GIP provides a novel link between the immune system and the gut, with proinflammatory-immune modulatory function but minor glucose regulatory relevance in the context of acute endotoxemia.
  88. Douillet C, Huang M, Saunders R, Dover E, Zhang C, Styblo M. Knockout of arsenic (+3 oxidation state) methyltransferase is associated with adverse metabolic phenotype in mice: the role of sex and arsenic exposure. Arch Toxicol. 2017;91:2617-2627 pubmed publisher
    ..of iAs exposure on fasting blood glucose (FBG) and glucose tolerance in either WT or KO mice were relatively minor and varied during the exposure. The major effects were associated with As3mt KO...
  89. Marques C, Costa G, da Silva T, Oliveira P, Cruz A, Alcantara Neves N, et al. Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. Eur J Hum Genet. 2017;25:439-445 pubmed publisher
    ..role of the rs12007907 on the production a Th2-type cytokine, IL-13, we found a negative association between the minor allele A with IL-13 production in the discovery set (P=0.044)...
  90. Razmjou H, Christakis M, Dwyer T, van Osnabrugge V, Holtby R. Accuracy of infraspinatus isometric testing in predicting tear size and tendon reparability: comparison with imaging and arthroscopy. J Shoulder Elbow Surg. 2017;26:1390-1398 pubmed publisher
    ..Sixty patients (71%) had a minor tear (4 small, 56 moderate), and 25 patients (29%) had a major tear (17 large and 8 massive)...
  91. Spencer J, Louie M, Moulder J, Ellis V, Schiff L, Toubia T, et al. Cost-effectiveness of treatments for heavy menstrual bleeding. Am J Obstet Gynecol. 2017;217:574.e1-574.e9 pubmed publisher
    ..For each treatment option, we used probabilities derived from literature review to estimate frequencies of minor complications, major complications, and treatment failure resulting in the need for additional treatments...
  92. Palazzi M, Cerrotta A, Villa S. Altered fractionation radiotherapy in lung cancer. Tumori. 1998;84:171-5 pubmed
    ..hypofractionation with a palliative aim; in small-cell lung cancer (SCLC) altered fractionation seems to play a minor role at this moment. In this review paper the results of reported randomised trials are summarised and discussed...