NFIC

Summary

Gene Symbol: NFIC
Description: nuclear factor I C
Alias: CTF, CTF5, NF-I, NFI, nuclear factor 1 C-type, CCAAT-box-binding transcription factor, NF-I/C, NF1-C, TGGCA-binding protein, nuclear factor I/C (CCAAT-binding transcription factor)
Species: human
Products:     NFIC

Top Publications

  1. Plasari G, Calabrese A, Dusserre Y, Gronostajski R, McNair A, Michalik L, et al. Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression. Mol Cell Biol. 2009;29:6006-17 pubmed publisher
    ..The nuclear factor I C (NFI-C) transcription factor has been implicated in TGF-beta signaling, extracellular matrix deposition, and skin ..
  2. Nilsson J, Helou K, Kovács A, Bendahl P, Bjursell G, Fernö M, et al. Nuclear Janus-activated kinase 2/nuclear factor 1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing Forkhead box F1. Cancer Res. 2010;70:2020-9 pubmed publisher
    ..The relevance of these findings is strengthened by the correlation between FoxF1 expression and a mesenchymal phenoype in breast cancer cell isolates, consistent with the interpretation that FoxF1 promotes invasion and metastasis. ..
  3. Lee D, Yoon W, Cho E, Kim H, Gronostajski R, Cho M, et al. Crosstalk between nuclear factor I-C and transforming growth factor-?1 signaling regulates odontoblast differentiation and homeostasis. PLoS ONE. 2011;6:e29160 pubmed publisher
    ..Nuclear factor I-C (NFI-C) has been implicated in TGF-?1 signaling, extracellular matrix gene transcription, and tooth root development...
  4. Martinez R, Pinho Ribeiro F, Vale D, Steffen V, Vicentini F, Vignoli J, et al. Trans-chalcone added in topical formulation inhibits skin inflammation and oxidative stress in a model of ultraviolet B radiation skin damage in hairless mice. J Photochem Photobiol B. 2017;171:139-146 pubmed publisher
    ..Control topical formulation (CTF) and TFcTC were applied in hairless mice before and after exposure to UVB radiation...
  5. Chen L, Chai K. Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Oncotarget. 2017;8:56490-56505 pubmed publisher
    ..Matriptase cleaves phosphorylated Her2 at Arg558 and Arg599 and the Arg599 cleavage produces a CTF not recognized by the monoclonal antibody trastuzumab/Herceptin...
  6. Rawat V, Goux W, Piechaczyk M, D Mello S. c-Fos Protects Neurons Through a Noncanonical Mechanism Involving HDAC3 Interaction: Identification of a 21-Amino Acid Fragment with Neuroprotective Activity. Mol Neurobiol. 2016;53:1165-80 pubmed publisher
    ..This cell-permeable peptide, designated as Fos-CTF, could have potential as a therapeutic agent for neurodegenerative diseases.
  7. Kumar V, Chaker El Khoury J, GRONOSTAJSKI R, Wang H, Nielsen L, Ryan R. Nfib hemizygous mice are protected from hyperoxic lung injury and death. Physiol Rep. 2017;5: pubmed publisher
    Nuclear Factor I (Nfi) genes encode transcription factors essential for the development of organ systems including the lung. Nfib null mice die at birth with immature lungs...
  8. Estrada Rivera M, Rebolledo Prudencio O, Pérez Robles D, Rocha Medina M, González López M, Casas Flores S. Trichoderma Histone Deacetylase HDA-2 Modulates Multiple Responses in Arabidopsis. Plant Physiol. 2019;179:1343-1361 pubmed publisher
    ..of Arabidopsis, low levels of epl-1 and abc-2 compared with that in the wild type; whereas ctf-1 presented high constitutive levels, supporting a dual role of HDA-2 in gene regulation...
  9. Dai J, Kumbhare A, Youssef D, Yao Z, McCall C, El Gazzar M. Expression of C/EBPβ in myeloid progenitors during sepsis promotes immunosuppression. Mol Immunol. 2017;91:165-172 pubmed publisher
    ..protein C/EBPβ activates microRNA (miR)-21 and miR-181b expressions, which induce transcription factor NFI-A to support the generation and expansion of MDSCs in the bone marrow and spleens of septic mice...

More Information

Publications136 found, 100 shown here

  1. Zhao L, Wang J, Liu R, Li X, Li J, Zhang L. Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model. Molecules. 2013;18:9949-65 pubmed publisher
    ..also showed effects affecting APP processing and preventing Aβ burden due to the down-regulation of BACE1 and β-CTF levels, the relief of Aβ deposition, and the decrease of insoluble Aβ levels...
  2. el Azzouni M, Mady R, Gaafar M, Arafa F, Elhadidi A. Protective capacity of cercarial transformation fluid alone or in combination with crude cercarial antigen against challenge infections of Schistosoma mansoni in mice. J Helminthol. 2017;91:35-42 pubmed publisher
    ..We assessed the effect of cercarial transformation fluid (CTF) singly and in combination with crude cercarial antigen (CCA) using alum as an adjuvant...
  3. Kitamura A, Yuno S, Muto H, Kinjo M. Different aggregation states of a nuclear localization signal-tagged 25-kDa C-terminal fragment of TAR RNA/DNA-binding protein 43 kDa. Genes Cells. 2017;22:521-534 pubmed publisher
    ..We recently reported that a nuclear localization signal (NLS)-tagged 25-kDa CTF of TDP-43 (TDP25) could decrease the cell-death proportion compared with that promoted by TDP25...
  4. McClure C, Ali E, Youssef D, Yao Z, McCall C, El Gazzar M. NFI-A disrupts myeloid cell differentiation and maturation in septic mice. J Leukoc Biol. 2016;99:201-11 pubmed publisher
    ..We suggest that therapeutically targeting nuclear factor 1 A type during late sepsis might improve survival. ..
  5. Ye X, Sun Y, Ju W, Wang X, Cao W, Wu M. Vector competence of the tick Ixodes sinensis (Acari: Ixodidae) for Rickettsia monacensis. Parasit Vectors. 2014;7:512 pubmed publisher
    ..monacensis using capillary tube feeding (CTF) or immersion techniques...
  6. Liu S, Yan Y, Gao X, Xiang S, Sha T, Zeng G, et al. Risk factors for postpartum depression among Chinese women: path model analysis. BMC Pregnancy Childbirth. 2017;17:133 pubmed publisher
    ..687, cmin/df = 0.824, nfi = 0.992, rfi = 0.982, ifi = 1.002, tli =1.004, cfi = 1...
  7. Dalhus B, Alseth I, Bjørås M. Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V. Prog Biophys Mol Biol. 2015;117:134-142 pubmed publisher
    ..Prokaryotic endonuclease V (EndoV/Nfi) has long been known to incise DNA 3' to a variety of base lesions, including deaminated adenine, guanine and ..
  8. Canu N, Pagano I, La Rosa L, Pellegrino M, Ciotti M, Mercanti D, et al. Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents. Front Mol Neurosci. 2017;10:15 pubmed publisher
    ..mechanisms, all caused dissociation of APP/TrkA complexes and increased production of C-terminal fragment (?-CTF) APP fragment...
  9. Aghajanirefah A, Nguyen L, Ohadi M. BEND3 is involved in the human-specific repression of calreticulin: Implication for the evolution of higher brain functions in human. Gene. 2016;576:577-80 pubmed publisher
    ..repressor BEN domain containing 3 (BEND3) binds to the human-specific C-allele, whereas the nuclear factor I (NFI) family members, NF1A, B, C, and X, specifically bind to the ancestral A-allele...
  10. Pelletier J, Kwong R, Park S, Le B, Baden R, Cagliari A, et al. LEC1 sequentially regulates the transcription of genes involved in diverse developmental processes during seed development. Proc Natl Acad Sci U S A. 2017;114:E6710-E6719 pubmed publisher
    ..Moreover, our results demonstrate strong conservation in the developmental processes and gene networks regulated by LEC1 in two dicotyledonous plants that diverged ?92 Mya. ..
  11. Rezai Zadeh K, Douglas Shytle R, Bai Y, Tian J, Hou H, Mori T, et al. Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production. J Cell Mol Med. 2009;13:574-88 pubmed publisher
    ..amyloidogenic gamma-secretase APP processing, and (ii) promote presenilin-1 (PS1) carboxyl-terminal fragment (CTF) phosphorylation...
  12. Stokol T, Daddona J, DeLeonardis C, Dong L, Wagner B. Generation and characterization of a monoclonal antibody against canine tissue factor. Vet Immunol Immunopathol. 2015;167:178-84 pubmed publisher
    ..We generated a murine mAb against canine TF (cTF) cloned from Madin-Darby canine kidney cells and expressed in Chinese Hamster Ovarian (CHO) cells, with an equine ..
  13. Kitamura A, Nakayama Y, Shibasaki A, Taki A, Yuno S, Takeda K, et al. Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity. Sci Rep. 2016;6:19230 pubmed publisher
    ..in individual live cells showed that fluorescent-protein-tagged TDP43 was cleaved and a 35 kDa TDP43 CTF (TDP35) formed ubiquitin (Ub)-negative cytoplasmic IBs...
  14. Liu Q, Van Bortle K, Zhang Y, Zhao M, Zhang J, Geller B, et al. Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Sci Rep. 2018;8:12960 pubmed publisher
    ..that INN-exposure leads to enhanced DNA-binding of specific transcription factors (TFs), including HNF1B, SOX10 and NFIC, often in close spatial proximity to genes that are dysregulated in response to INN treatment...
  15. Kaku M, Yamamoto T, Yashima Y, Izumino J, Kagawa H, Ikeda K, et al. Acetaminophen reduces apical root resorption during orthodontic tooth movement in rats. Arch Oral Biol. 2019;102:83-92 pubmed publisher
    ..Human periodontal ligament and pulp cells were subjected to 10 kPa of cyclic tensile force (CTF) in a Flexcell Strain Unit for 48 h...
  16. Hammond F, Sauve W, Ledon F, Davis C, Formella A. Safety, Tolerability, and Effectiveness of Dextromethorphan/Quinidine for Pseudobulbar Affect Among Study Participants With Traumatic Brain Injury: Results From the PRISM-II Open Label Study. PM R. 2018;10:993-1003 pubmed publisher
    ..Quality of Life-Visual Analog Scale (QOL-VAS), treatment satisfaction, Neurobehavioral Functioning Inventory (NFI), Patient Health Questionnaire (PHQ-9), and Mini Mental State Examination (MMSE)...
  17. Kim H, Lee W, Kim M, Shin S, Jang B, Park J, et al. Calsenilin, a Presenilin Interactor, Regulates RhoA Signaling and Neurite Outgrowth. Int J Mol Sci. 2018;19: pubmed publisher
    ..Interestingly, PC12 cells overexpressing either full-length (FL) or the caspase 3-derived C-terminal fragment (CTF) of calsenilin significantly inactivated RhoA through its interaction with RhoA and p190 Rho GTPase-activating ..
  18. Lake J, Zaniolo K, Gingras M, Couture C, Salesse C, Guérin S. Functional Impact of Collagens on the Activity Directed by the Promoter of the α5 Integrin Subunit Gene in Corneal Epithelial Cells. Invest Ophthalmol Vis Sci. 2015;56:6217-32 pubmed publisher
    ..collagen-dependent regulatory influences also correlated with alterations in the transcription factors Sp1/Sp3, NFI, and AP-1 that ensure α5 gene basal transcription...
  19. Fraser J, Essebier A, Gronostajski R, Boden M, Wainwright B, Harvey T, et al. Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain Struct Funct. 2017;222:2251-2270 pubmed publisher
    Transcription factors from the nuclear factor one (NFI) family have been shown to play a central role in regulating neural progenitor cell differentiation within the embryonic and post-natal brain...
  20. Molanorouzi K, Khoo S, Morris T. Validating the Physical Activity and Leisure Motivation Scale (PALMS). BMC Public Health. 2014;14:909 pubmed publisher
    ..The hypothesized 8-factor model demonstrated a good fit with the data (CMIN/DF = 2.820, NFI = 0.90, CFI = 0.91, RMSEA = 0.06). Cronbach's alpha coefficient (α = 0...
  21. Sieswerda Hoogendoorn T, Beenen L, van Rijn R. Normal cranial postmortem CT findings in children. Forensic Sci Int. 2015;246:43-9 pubmed publisher
    ..One-hundred-fifty-nine forensic pediatric autopsies were performed in the 4 year study period at the NFI; 77 underwent a total body PMCT, of which 68 were included in the analyses...
  22. Duval C, Zaniolo K, Leclerc S, Salesse C, Guérin S. Characterization of the human α9 integrin subunit gene: Promoter analysis and transcriptional regulation in ocular cells. Exp Eye Res. 2015;135:146-63 pubmed publisher
    ..DNaseI footprinting and in vivo ChIP analyses demonstrated the binding of the transcription factors Sp1, c-Myb and NFI to the most upstream α9 negative regulatory element...
  23. Ashaie M, Chowdhury E. Cadherins: The Superfamily Critically Involved in Breast Cancer. Curr Pharm Des. 2016;22:616-38 pubmed
    ..serves as hallmark of EMT is associated with several regulatory factors such as Snail, Slug, Twist, Zeb, KLF4, NFI, TBX2, SIX, b-Myb, COX-2, Arf6, FOXA2, GATA3 and SMAR1, which modulate E-cadherin gene transcription to promote or ..
  24. Foy R, Chitalia V, Panchenko M, Zeng L, Lopez D, Lee J, et al. Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1. Hum Mol Genet. 2012;21:5456-71 pubmed publisher
    ..In contrast, the cytoplasmic tail or the naturally occurring C-terminal fragment of PC1 (PC1-CTF) promoted Jade-1 ubiquitination and degradation, suggesting a dominant-negative mechanism...
  25. Heng Y, Zhou B, Harris L, Harvey T, Smith A, Horne E, et al. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Cereb Cortex. 2015;25:3758-78 pubmed publisher
    Transcription factors of the nuclear factor one (NFI) family play a pivotal role in the development of the nervous system. One member, NFIX, regulates the development of the neocortex, hippocampus, and cerebellum...
  26. O Connor C, Campos J, Osinski J, Gronostajski R, Michie A, Keeshan K. Nfix expression critically modulates early B lymphopoiesis and myelopoiesis. PLoS ONE. 2015;10:e0120102 pubmed publisher
    ..Nuclear factor one (NFI) transcription factors are important in regulating hematopoiesis and here we report an important physiological role ..
  27. Krishnan A, Nijmeijer S, de Graaf C, Schioth H. Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs. Handb Exp Pharmacol. 2016;234:15-41 pubmed
    ..GAIN) domain, that mediates autoproteolysis and subsequent attachment of the cleaved NTF and CTF fragments The adhesion family of G protein-coupled receptors (aGPCRs) is unique among all GPCR families with long N-..
  28. Takahashi M, Ishikawa K, Sato N, Obayashi M, Niimi Y, Ishiguro T, et al. Reduced brain-derived neurotrophic factor (BDNF) mRNA expression and presence of BDNF-immunoreactive granules in the spinocerebellar ataxia type 6 (SCA6) cerebellum. Neuropathology. 2012;32:595-603 pubmed publisher
    ..predominant neuronal loss is the characteristic neuropathology of SCA6, and a 75-kDa carboxy-terminal fragment (CTF) of Ca(v) 2...
  29. Liefke R, Bokelmann K, Ghadimi B, Dango S. Enhancer-driven transcriptional regulation is a potential key determinant for human visceral and subcutaneous adipocytes. Biochim Biophys Acta Gene Regul Mech. 2018;: pubmed publisher
    ..of subcutaneous adipocytes show enrichment of motifs for common adipogenic transcription factors, such as C/EBP, NFI and PPAR?, implicating substantially disparate gene regulatory networks in visceral and subcutaneous adipocytes...
  30. Willem M, Tahirovic S, Busche M, Ovsepian S, Chafai M, Kootar S, et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015;526:443-7 pubmed publisher
    ..We identify higher molecular mass carboxy-terminal fragments (CTFs) of APP, termed CTF-η, in addition to the long-known CTF-α and CTF-β fragments generated by the α- and β-secretases ..
  31. Kim M, Ryu E. [Structural Equation Modeling of Quality of Work Life in Clinical Nurses based on the Culture-Work-Health Model]. J Korean Acad Nurs. 2015;45:879-89 pubmed publisher
    ..03, χ²/df=4.19, GFI=.89, AGFI=.85, CFI=.91, TLI=.90, NFI=.89, and RMSEA=.08...
  32. Karmakar A, Kumar A, Chaudhari A, Samanta P, Desai A, Krishna R, et al. Bimodal Functionality in a Porous Covalent Triazine Framework by Rational Integration of an Electron-Rich and -Deficient Pore Surface. Chemistry. 2016;22:4931-7 pubmed publisher
    A porous covalent triazine framework (CTF) consisting of both an electron-deficient central triazine core and electron-rich aromatic building blocks is reported...
  33. Wang B, Lee L, Wei C, Fu H, Zheng S, Xu Z, et al. Covalent triazine-based framework: A promising adsorbent for removal of perfluoroalkyl acids from aqueous solution. Environ Pollut. 2016;216:884-892 pubmed publisher
    ..The main objective of this study was to assess a covalent triazine-based framework (CTF) adsorbent for removal from aqueous solutions of perfluoro C4, C6, and C8 carboxylates and sulfonates including the ..
  34. Kim J, Song Y. [Health Promoting Behavior in Pregnant Couples: Actor-Partner Interdependence Model Analysis]. J Korean Acad Nurs. 2017;47:467-475 pubmed publisher
    ..The fitness indices for the model were GFI=0.90, NFI=0.92, CFI=0.91, TLI=0.90, and RMSEA=0.04, which satisfied the criteria...
  35. Ren J, Wang X, Li X, Wang M, Zhao R, Lin J. Magnetic covalent triazine-based frameworks as magnetic solid-phase extraction adsorbents for sensitive determination of perfluorinated compounds in environmental water samples. Anal Bioanal Chem. 2018;410:1657-1665 pubmed publisher
    ..This work aims to investigate the feasibility of using covalent triazine-based framework (CTF)/Fe2O3 composites as MSPE adsorbents to enrich and analyze perfluorinated compounds (PFCs) at ..
  36. Zhao J, Brubaker M, Benlekbir S, Rubinstein J. Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images. J Struct Biol. 2015;192:209-15 pubmed publisher
    ..Further, anisotropic magnification causes contrast transfer function (CTF) parameters estimated from image power spectra to have an apparent systematic astigmatism...
  37. de Graaf C, Nijmeijer S, Wolf S, Ernst O. 7TM Domain Structure of Adhesion GPCRs. Handb Exp Pharmacol. 2016;234:43-66 pubmed
    ..functional domains, covering an extracellular N-terminal fragment (NTF), a membrane-spanning C-terminal fragment (CTF) and a GPCR proteolysis site (GPS)...
  38. Li X, Zheng S, Agard D, Cheng Y. Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage. J Struct Biol. 2015;192:174-8 pubmed publisher
    ..This facilitates efficient acquisition, on-the-fly motion correction, and CTF analysis of dose fractionated image stacks with a total time of ∼60s/exposure...
  39. Galaz Montoya J, Hecksel C, Baldwin P, Wang E, Weaver S, Schmid M, et al. Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography. J Struct Biol. 2016;194:383-94 pubmed publisher
    ..Robust methods to correct for the contrast transfer function (CTF) of the electron microscope are necessary for cryoSPT to reach its resolution potential...
  40. Guix F, Sannerud R, Berditchevski F, Arranz A, Horré K, Snellinx A, et al. Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments. Mol Neurodegener. 2017;12:25 pubmed publisher
    ..exerts paradoxical effects on Amyloid Precursor Protein (APP) metabolism, increasing APP-C-terminal fragments (APP-CTF) and Aβ levels at the same time...
  41. Ye Z, Qiu H, Li P, Chen P, Liang M, Liu M, et al. Validation and application of the Chinese version of the 10-item Connor-Davidson Resilience Scale (CD-RISC-10) among parents of children with cancer diagnosis. Eur J Oncol Nurs. 2017;27:36-44 pubmed publisher
    ..987, CMIN/DF = 1.333, P < 0.001, TLI = 0.914, CFI = 0.981, GFI = 0.962, NFI = 0.926, IFI = 0.979, RFI = 0.889, RMR = 0.042, and RMSEA = 0.041...
  42. Chacón Cuberos R, Zurita Ortega F, Castro Sánchez M, Espejo Garcés T, Martínez Martínez A, Ruiz Rico Ruiz G. The association of Self-concept with Substance Abuse and Problematic Use of Video Games in University Students: A Structural Equation Model. Adicciones. 2018;30:179-188 pubmed publisher
    ..A model of structural equations was estimated, which was adjusted properly, χ2(8) = 19.843, p = .011; CFI = .963, NFI = .943, IFI = .965, RMSEA = .055...
  43. Behringer M, Nowak S, Leyendecker J, Mester J. Effects of TRPV1 and TRPA1 activators on the cramp threshold frequency: a randomized, double-blind placebo-controlled trial. Eur J Appl Physiol. 2017;117:1641-1647 pubmed publisher
    ..We tested the cramp threshold frequency (CTF), the cramp intensity (EMG activity), and the perceived pain of electrically induced muscle cramps before (pre), ..
  44. Koeck P. Design of an electrostatic phase shifting device for biological transmission electron microscopy. Ultramicroscopy. 2018;187:107-112 pubmed publisher
    ..At higher defocus the low frequency behavior is equal to that close to Scherzer defocus, but CTF-correction becomes necessary to extend image interpretation to higher resolution...
  45. Kaneshiro N, Imaoka R, Komai M, Kashiyama T, Sakurai T, Uehara T, et al. Functional analysis of juxta- and intra-membrane domains of murine APP by genome editing in Neuro2a cells. Biochem Biophys Res Commun. 2018;: pubmed publisher
    ..overall levels of APP metabolites or decreased the level of ?-secretase-cleaved carboxy-terminal fragment (?CTF), respectively...
  46. de Boer H, Van der Merwe A, Soerdjbalie Maikoe V. Human cranial vault thickness in a contemporary sample of 1097 autopsy cases: relation to body weight, stature, age, sex and ancestry. Int J Legal Med. 2016;130:1371-7 pubmed publisher
    ..sex, and ancestry by reviewing data of 1097 forensic autopsies performed at the Netherlands Forensic Institute (NFI)...
  47. Li N, Liu K, Qiu Y, Ren Z, Dai R, Deng Y, et al. Effect of Presenilin Mutations on APP Cleavage; Insights into the Pathogenesis of FAD. Front Aging Neurosci. 2016;8:51 pubmed publisher
    ..More importantly, we found some mutations can affect the γ-secretase cleavage preference of α-CTF and β-CTF...
  48. Han M, Wan J, Zhao Y, Zhou X, Wan M. Nakagami-m Parametric Imaging for Atherosclerotic Plaque Characterization Using the Coarse-to-Fine Method. Ultrasound Med Biol. 2017;43:1275-1289 pubmed publisher
    ..Nakagami-m parametric imaging using the coarse-to-fine method based on the maximum likelihood estimation (CTF-BOW) was proposed for atherosclerotic plaque characterization...
  49. Xiao R, Lai Q, Yang J. [Reliability and validity of Meaningful Life Measure-Chinese Revised in Chinese college students]. Nan Fang Yi Ke Da Xue Xue Bao. 2016;37:499-504 pubmed
    ..4, GFI=0.946, AGFI=0.924, RMR=0.069, NFI=0.953, CFI=0.966, RMSEA=0.048). The total internal consistency reliability of MLM-CR was 0...
  50. Román Cereto M, García Mayor S, Kaknani Uttumchandani S, García Gámez M, Leon Campos Á, Fernández Ordóñez E, et al. Cultural adaptation and validation of the Lasater Clinical Judgment Rubric in nursing students in Spain. Nurse Educ Today. 2018;64:71-78 pubmed publisher
    ..08, GFI 0.96, TLI 0.99, NFI 0.97 and RMSEA 0.24 (90% CI 0.000-0.066)...
  51. Urbazaev M, Thiel C, Cremer F, Dubayah R, Migliavacca M, Reichstein M, et al. Estimation of forest aboveground biomass and uncertainties by integration of field measurements, airborne LiDAR, and SAR and optical satellite data in Mexico. Carbon Balance Manag. 2018;13:5 pubmed publisher
    ..We modelled AGB using two scenarios: (1) extensive national forest inventory (NFI), and (2) airborne Light Detection and Ranging (LiDAR) as reference data...
  52. Girouard M, Pool M, Alchini R, Rambaldi I, Fournier A. RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. PLoS ONE. 2016;11:e0168641 pubmed publisher
    ..Overexpression of either RhoA-NTF or the carboxy-terminal RhoA cleavage fragment (RhoA-CTF) induces the formation of disorganized actin stress fibres...
  53. Cui W, Sun Y, Wang Z, Xu C, Xu L, Wang F, et al. Activation of liver X receptor decreases BACE1 expression and activity by reducing membrane cholesterol levels. Neurochem Res. 2011;36:1910-21 pubmed publisher
    ..cholesterol levels, reduced BACE1 expression and activity as well as ?-secretase cleaved C-terminal fragment (?-CTF) levels in vivo and in vitro...
  54. Zhang Y, Yang Y, Lv J, Zhang Y. LC-PROM: Validation of a patient reported outcomes measure for liver cirrhosis patients. Health Qual Life Outcomes. 2016;14:75 pubmed publisher
    ..fit index as Root Mean Square Error of Approximation (RMSEA), Root Mean Square Residual (RMR), Normed Fit Index (NFI), Non-Normed Fit Index (NNFI), Comparative Fit Index (CFI) and Incremental Fit Index (IFI) met the criterion ..
  55. Yu K, Locatelli A, Altman M. Comparing Fourier optics and contrast transfer function modeling of image formation in low energy electron microscopy. Ultramicroscopy. 2017;183:109-116 pubmed publisher
    ..We compare Fourier Optics (FO) and Contrast Transfer Function (CTF) approaches that were recently adapted from other realms of microscopy to model image formation in low energy ..
  56. Williamson R, Laulagnier K, Miranda A, Fernandez M, Wolfe M, Sadoul R, et al. Disruption of amyloid precursor protein ubiquitination selectively increases amyloid ? (A?) 40 levels via presenilin 2-mediated cleavage. J Biol Chem. 2017;292:19873-19889 pubmed publisher
    ..vesicles (ILVs) to the endosomal limiting membrane, with a subsequent decrease in APP C-terminal fragment (CTF) content in secreted exosomes, but had minimal effects on APP lysosomal degradation...
  57. Su K, Lin L, Goodman S, Yen R, Wu C, Chang W, et al. DNA polymerase I proofreading exonuclease activity is required for endonuclease V repair pathway both in vitro and in vivo. DNA Repair (Amst). 2018;64:59-67 pubmed publisher
    ..In Escherichia coli, dI repair is initiated by endonuclease V (endo?V; nfi gene product) nicking but a complete repair mechanism has yet to be elucidated...
  58. Minami S, Cordova A, Cirrito J, Tesoriero J, Babus L, Davis G, et al. ApoE mimetic peptide decreases Abeta production in vitro and in vivo. Mol Neurodegener. 2010;5:16 pubmed publisher
    ..We previously showed that the apoE dimer increased APP CTF in vivo; to determine whether the dimer also affected secreted APP or Abeta levels, we performed a single ..
  59. Bunt J, Lim J, Zhao L, Mason S, Richards L. PAX6 does not regulate Nfia and Nfib expression during neocortical development. Sci Rep. 2015;5:10668 pubmed publisher
    The Nuclear factor I (NFI) family of transcription factors regulates proliferation and differentiation throughout the developing central nervous system...
  60. Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey T, et al. Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development. 2016;143:4620-4630 pubmed
    ..Loss of additional Nfi alleles (Nfib) resulted in a severe delay in IPC generation while, conversely, overexpression of NFIX led to ..
  61. Voicu M, Shaw C, Kurz W, Huffman T, Liu J, Fellows M. Carbon dynamics on agricultural land reverting to woody land in Ontario, Canada. J Environ Manage. 2017;193:318-325 pubmed publisher
    ..a scale of 1:10,000 or larger were randomly selected from the 20 km × 20 km National Forest Inventory (NFI) grid...
  62. Zeng D, Kang Y, Xie L, Xia X, Wang Z, Liu W. A Mathematical Model and Experimental Verification of Optimal Nozzle Diameter in Needle-Free Injection. J Pharm Sci. 2018;107:1086-1094 pubmed publisher
    Needle-free injection (NFI), as an alternative drug delivery strategy, owns great potential. It is able to reduce complaints about needle phobia and avoid the occurring of accidental needle stick injuries...
  63. Maulik M, Peake K, Chung J, Wang Y, Vance J, Kar S. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease. Hum Mol Genet. 2015;24:7132-50 pubmed publisher
    ..Levels of APP C-terminal fragments (α-CTF/β-CTF) and Aβ peptides, but not APP mRNA/protein or soluble APPα/APPβ, were increased in ANPC mouse ..
  64. Kristjansson S, McCutcheon V, Agrawal A, Lynskey M, Conroy E, Statham D, et al. The variance shared across forms of childhood trauma is strongly associated with liability for psychiatric and substance use disorders. Brain Behav. 2016;6:e00432 pubmed publisher
    ..sexual abuse, and parental partner abuse) and, as hypothesized, one higher order, childhood trauma factor (CTF) representing a measure of their common variance...
  65. Tromp R, Altman M. Defocus in cathode lens instruments. Ultramicroscopy. 2017;183:2-7 pubmed publisher
    ..PEEM) is a pre-requisite for quantitative image analysis using Fourier Optics (FO) or Contrast Transfer Function (CTF) image simulations...
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    ..site (?-site) of A? in APP but at the Glu11 site (?'-site) to increase C89 carboxyl-terminal fragment levels (?'-CTF/C89). The levels of N-terminally truncated A?11-40 peptides were also increased by ABCA2 expression...
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    ..Moreover, expression of the ?-C-terminal fragment (?-CTF) of APP was markedly low in the mitochondria-enriched fraction...
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    ..In 2001, we mailed again the same questionnaire to the same referral Centers in Italy. The aim of the second enquiry was the evaluation of changes in endometrial cancer management and the effective impact of the guidelines published...
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    ..We also observed that rhPAI-1 upregulated the expression of Smad4, nuclear factor I-C (NFI-C), Runx2, and osterix (OSX) during odontogenic differentiation...
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