neurofilament M


Gene Symbol: neurofilament M
Description: neurofilament medium
Alias: NEF3, NF-M, NFM, neurofilament medium polypeptide, 160 kDa neurofilament protein, neurofilament 3, neurofilament triplet M protein, neurofilament, medium polypeptide 150kDa, neurofilament-3 (150 kD medium)
Species: human
Products:     neurofilament M

Top Publications

  1. Xu Z, Liu W, Willard M. Identification of six phosphorylation sites in the COOH-terminal tail region of the rat neurofilament protein M. J Biol Chem. 1992;267:4467-71 pubmed
    ..The identification of these sites should aid in investigations of the function of the phosphorylation of this protein and provides criteria for identifying the relevant kinases. ..
  2. Tu P, Elder G, Lazzarini R, Nelson D, Trojanowski J, Lee V. Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits. J Cell Biol. 1995;129:1629-40 pubmed
    ..system (CNS) and peripheral nervous system (PNS) neurons, are heteropolymers formed from the high (NFH), middle (NFM), and low (NFL) molecular weight NF subunits...
  3. Casanova M, Alves da Silva M, Costa Pinto A, Reis R, Martins A, Neves N. Chondrogenesis-inductive nanofibrous substrate using both biological fluids and mesenchymal stem cells from an autologous source. Mater Sci Eng C Mater Biol Appl. 2019;98:1169-1178 pubmed publisher
    ..Therefore, these two growth factors (GFs) were immobilized at the surface of a single electrospun nanofibrous mesh (NFM) aiming to differentiate human Bone Marrow-derived Mesenchymal Stem Cells (hBM-MSCs)...
  4. Li B, Luo X, Wen Y. Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age. J Mol Histol. 2019;: pubmed publisher
    ..The total quantity of mechanoreceptors reaches a peak in 3 months, while NEFM and S100B reach a peak in 1 year. ..
  5. Chao D, Chen J, Huang S, Tyan C, Hsieh C, Sheen L. Effects of hot and cold foods on signals of heart rate variability and nail fold microcirculation of healthy young humans: a pilot study. Chin J Physiol. 2011;54:145-52 pubmed
    ..We found that the capillary red blood cell (RBC) velocity in nail fold microcirculation (NFM) of the subjects with hot constitution accelerated significantly after taking the hot-attribute aged ginger tea, ..
  6. Her Q, Amato M, Seger D, Beeler P, Slight S, Dalleur O, et al. The frequency of inappropriate nonformulary medication alert overrides in the inpatient setting. J Am Med Inform Assoc. 2016;23:924-33 pubmed publisher
    ..Our objectives were to quantify the frequency of inappropriate nonformulary medication (NFM) alert overrides in the inpatient setting and provide insight on how the design of formulary alerts could be ..
  7. Lee C, Yang H, Chen C, Lin C, Wu H, Chung W, et al. Empirical versus progression-guided stereotactic radiosurgery for non-functional pituitary macroadenomas after subtotal resection. J Neurooncol. 2019;142:291-297 pubmed publisher
    There is a lack of consensus regarding whether if residual non-functional macroadenomas (NFM) should undergo empirical stereotactic radiosurgery (SRS) or be monitored until tumor progression before SRS treatment...
  8. Chen S, Chen C, Fong Y, Chen J. Prevention of peritendinous adhesions with electrospun chitosan-grafted polycaprolactone nanofibrous membranes. Acta Biomater. 2014;10:4971-4982 pubmed publisher
    ..membranes, we propose the use of an electrospun chitosan-grafted polycaprolactone (PCL-g-CS) nanofibrous membrane (NFM) to prevent peritendinous adhesions...
  9. Sassone J, Taiana M, Lombardi R, Porretta Serapiglia C, Freschi M, Bonanno S, et al. ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin. Hum Mol Genet. 2016;25:1588-99 pubmed publisher
    ..peripherin56, which causes axonal stress through disassembling light and medium neurofilament subunits (NFL and NFM, respectively)...

More Information

Publications116 found, 100 shown here

  1. McDonald J, Mah E, Dey P, Olmstead B, Sasaki G, Villamena F, et al. Dairy milk, regardless of fat content, protects against postprandial hyperglycemia-mediated impairments in vascular endothelial function in adults with prediabetes by limiting oxidative stress responses that reduce nitric oxide bioavailability. J Nutr Biochem. 2019;63:129-139 pubmed publisher
    ..ingested glucose (75 g) dissolved in 473 ml of water (GLU), or glucose with an equal volume of nonfat dairy milk (NFM) or full-fat dairy milk (FFM)...
  2. Chen S, Lv C, Hao K, Jin L, Xie Y, Zhao W, et al. Multifunctional negatively-charged poly (ether sulfone) nanofibrous membrane for water remediation. J Colloid Interface Sci. 2019;538:648-659 pubmed publisher
    ..Herein, a cross-linked poly (acrylic acid) (PAA) modified poly (ether sulfone) nanofibrous membrane (NFM) was fabricated by a facile in-situ pre-reaction followed by electrospinning...
  3. Padil V, Černík M. Poly (vinyl alcohol)/gum karaya electrospun plasma treated membrane for the removal of nanoparticles (Au, Ag, Pt, CuO and Fe3O4) from aqueous solutions. J Hazard Mater. 2015;287:102-10 pubmed publisher
    ..The morphology, characterization and adsorption ability of P-NFM was assessed using scanning electron microscopy, UV-vis spectroscopy, ATR-FTIR techniques, water contact angle and ..
  4. Liu Q, Zheng Y, Zhong L, Cheng X. Removal of tetracycline from aqueous solution by a Fe3O4 incorporated PAN electrospun nanofiber mat. J Environ Sci (China). 2015;28:29-36 pubmed publisher
    ..In this work, a novel adsorbent, Fe3O4 incorporated polyacrylonitrile nanofiber mat (Fe-NFM), was successfully fabricated via electrospinning and solvothermal method, targeting to remove tetracycline (TC), a ..
  5. Abdelfattah E, Vezzoli G, Buczkowski G, Makagon M. Essential oils: effects of application rate and modality on potential for combating northern fowl mite infestations. Med Vet Entomol. 2018;32:304-310 pubmed publisher
    The northern fowl mite (NFM), Ornithonyssus sylviarum (Mesostigmata: Macronyssidae), is the primary blood-feeding ectoparasite found on poultry in the U.S.A...
  6. Li D, Zou X, El Ayachi I, Romero L, Yu Z, Iglesias Linares A, et al. Human Dental Pulp Stem Cells and Gingival Mesenchymal Stem Cells Display Action Potential Capacity In Vitro after Neuronogenic Differentiation. Stem Cell Rev. 2019;15:67-81 pubmed publisher
    ..Neuronal-like cells expressed βIII-tubulin, CNPase, GFAP, MAP-2, NFM, pan-Nav, GAD67, Nav1.6, NF1, NSE, PSD95, and synapsin after the second phase of differentiation to maturity...
  7. Bilad M, Azizo A, Wirzal M, Jia Jia L, Putra Z, Nordin N, et al. Tackling membrane fouling in microalgae filtration using nylon 6,6 nanofiber membrane. J Environ Manage. 2018;223:23-28 pubmed publisher
    ..This study evaluates performance of nylon 6,6 nanofiber membrane (NFM) to a conventional polyvinylidene fluoride phase inverted membrane (PVDF PIM) for filtration of Chlorella vulgaris...
  8. Smerjac S, Zheng J, Hu C, Bizzozero O. The Role of Calpain and Proteasomes in the Degradation of Carbonylated Neuronal Cytoskeletal Proteins in Acute Experimental Autoimmune Encephalomyelitis. Neurochem Res. 2018;43:2277-2287 pubmed publisher
    ..on total protein carbonylation or cytoskeletal protein degradation but increases the amount of oxidized NFH and NFM. These results suggest that while the proteasome may contribute to removal of oxidized NFPs, calpain is the main ..
  9. Han Q, Lin Q, Huang P, Chen M, Hu X, Fu H, et al. Microglia-derived IL-1? contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats. J Neuroinflammation. 2017;14:52 pubmed publisher
    ..The expression of neurofilament-68, neurofilament-160, and neurofilament-200 (NFL, NFM, NFH) and proteolipid (PLP) was markedly reduced in the CC at 7, 14, and 28 days after LPS administration...
  10. Triplett J, Zhang Z, Sultana R, Cai J, Klein J, Büeler H, et al. Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease. J Neurochem. 2015;133:750-65 pubmed publisher
    ..protein kinase 1; MEK1, MAP kinase kinase 1; MDHc, cytoplasmic malate dehydrogenase; NFM, neurofilament medium polypeptide; NSF, N-ethylmaleimide-sensitive fusion protein; PHB, prohibitin; PINK1, PTEN-induced putative kinase ..
  11. Heimfarth L, da Silva Ferreira F, Pierozan P, Mingori M, Moreira J, da Rocha J, et al. Astrocyte-neuron interaction in diphenyl ditelluride toxicity directed to the cytoskeleton. Toxicology. 2017;379:1-11 pubmed publisher
    ..caused hypophosphorylation of glial fibrillary acidic protein (GFAP), vimentin and neurofilament subunits (NFL, NFM and NFH) and altered actin organization in co-cultured astrocytes and neurons from cerebral cortex of rats...
  12. Tamm N, Brotsman V, Markov V, Kemnitz E, Troyanov S. Chlorination-promoted skeletal transformation of IPR C76 discovered via trifluoromethylation under the formation of non-IPR C76(CF3)nFm. Dalton Trans. 2018;47:6898-6902 pubmed publisher
    ..trifluoromethylation of non-IPR C76 chlorides with CF3I unexpectedly resulted in a series of non-IPR C76(CF3)nFm compounds...
  13. Vezzoli G, King A, Mench J. The effect of northern fowl mite (Ornithonyssus sylviarum) infestation on hen physiology, physical condition, and egg quality. Poult Sci. 2016;95:1042-9 pubmed publisher
    The northern fowl mite (NFM),Ornithonyssus sylviarum, is the most common ectoparasite of laying hens in North America. Infestation can cause a reduction in egg production, egg weights, and feed conversion efficiency...
  14. Cui X, Li T, Li J, An Y, An L, Zhang X, et al. A highly selective and reversible turn-off fluorescent chemosensor for Cu2+ based on electrospun nanofibrous membrane modified with pyrenecarboxaldehyde. Spectrochim Acta A Mol Biomol Spectrosc. 2019;207:173-182 pubmed publisher
    A fluorescent nanofibrous membrane (NFM) was successfully fabricated by functionalizing electrospun ethylene-vinyl alcohol copolymer (EVOH) NFM with 4‑aminobenzoic acid (PABA) and 1‑pyrenecarboxaldehyde (Py-CHO) for fast and ..
  15. Teerapanich P, Pugniere M, Henriquet C, Lin Y, Chou C, Leïchlé T. Nanofluidic Fluorescence Microscopy (NFM) for real-time monitoring of protein binding kinetics and affinity studies. Biosens Bioelectron. 2017;88:25-33 pubmed publisher
  16. Hänel L, Gosau T, Maar H, Valentiner U, Schumacher U, Riecken K, et al. Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases. Sci Rep. 2018;8:13986 pubmed publisher
    ..Summarized, this work identified several novel putative drivers of metastasis formation that are tempting candidates for future functional studies. ..
  17. Lankford L, Selby T, Becker J, Ryzhuk V, Long C, Farmer D, et al. Early gestation chorionic villi-derived stromal cells for fetal tissue engineering. World J Stem Cells. 2015;7:195-207 pubmed publisher
    ..found to express developmental transcription factors Sox10 and Sox17 as well as neural-related structural proteins NFM, Nestin, and S100β...
  18. Padil V, Stuchlík M, Černík M. Plasma modified nanofibres based on gum kondagogu and their use for collection of nanoparticulate silver, gold and platinum. Carbohydr Polym. 2015;121:468-76 pubmed publisher
    ..8 ± 2.3 nm and 10.5 ± 3.5 nm onto nanofibre membrane (NFM) and methane plasma treated membrane (P-NFM)...
  19. Li J, Xing X, Li D, Zhang B, Mutch D, Hagemann I, et al. Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma. Neoplasia. 2017;19:100-111 pubmed publisher
    ..Our findings highlight the epigenetic signatures that distinguish the two components of UCS, providing a valuable resource for investigation of this disease. ..
  20. Bardon C, Poly F, Piola F, Pancton M, Comte G, Meiffren G, et al. Mechanism of biological denitrification inhibition: procyanidins induce an allosteric transition of the membrane-bound nitrate reductase through membrane alteration. FEMS Microbiol Ecol. 2016;92:fiw034 pubmed publisher
    ..we investigate the mechanisms of BDI involving procyanidins, using the model strain Pseudomonas brassicacearum NFM 421. The aerobic and anaerobic (denitrification) respiration, cell permeability and cell viability of P...
  21. Schmitz F, Pierozan P, Biasibetti Brendler H, Ferreira F, dos Santos Petry F, Trindade V, et al. Methylphenidate disrupts cytoskeletal homeostasis and reduces membrane-associated lipid content in juvenile rat hippocampus. Metab Brain Dis. 2018;33:693-704 pubmed publisher
    ..weight neurofilament subunits (NF-M, NF-H) were hypophosphorylated by MPH on KSP repeat tail domains, while NFL, NFM and NFH immunocontents were not altered. MPH increased protein phosphatase 1 (PP1) and 2A (PP2A) immunocontents...
  22. Amaly N, Si Y, Chen Y, El Moghazy A, Zhao C, Zhang R, et al. Reusable anionic sulfonate functionalized nanofibrous membranes for cellulase enzyme adsorption and separation. Colloids Surf B Biointerfaces. 2018;170:588-595 pubmed publisher
    Poly (vinyl alcohol-co-ethylene) nanofibrous membranes (PVA-co-PE NFM) were successfully modified by sodium-3-sulfobenzoate to become negatively charged with sulfonate groups, and the sulfonated (PVA-co-PE) nanofiber membrane SS (PVA-co-..
  23. Penney K, Sinnott J, Tyekucheva S, Gerke T, Shui I, Kraft P, et al. Association of prostate cancer risk variants with gene expression in normal and tumor tissue. Cancer Epidemiol Biomarkers Prev. 2015;24:255-60 pubmed publisher
    ..These genes should be further explored in biologic and epidemiologic studies. Determining the biologic role of these variants can lead to improved understanding of prostate cancer etiology and identify new targets for chemoprevention. ..
  24. Zhou J, Lam B, Neogi S, Yeo G, Azizan E, Brown M. Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues. Hypertension. 2016;68:1424-1431 pubmed
    ..Further interrogation of these genes and pathways could potentially provide further insights into the pathology of primary aldosteronism. ..
  25. Wang X, Dou L, Yang L, Yu J, Ding B. Hierarchical structured MnO2@SiO2 nanofibrous membranes with superb flexibility and enhanced catalytic performance. J Hazard Mater. 2017;324:203-212 pubmed publisher
    ..nanostructured MnO2-immobilized SiO2 nanofibrous membranes (MnO2@SiO2 NFM) were fabricated by combining the electrospinning technique with hydrothermal method...
  26. Hu C, Zheng Y, Yu Z, Abell C, Scherman O. Surface-immobilised micelles via cucurbit[8]uril-rotaxanes for solvent-induced burst release. Chem Commun (Camb). 2015;51:4858-60 pubmed publisher
    The fabrication, characterisation and controlled burst release of naphthol-functionalised micellar (NFM) nanostructures, which were grafted onto gold surfaces through cucurbit[8]uril (CB[8]) mediated host-guest interactions are described...
  27. Kumari A, Yadav S, Misro M, Ahmad J, Ali S. Copy number variation and microdeletions of the Y chromosome linked genes and loci across different categories of Indian infertile males. Sci Rep. 2015;5:17780 pubmed publisher
    ..43 oligospermic (OS), and 40 infertile males with normal spermiogram (INS) together with 55 normal fertile males (NFM) from the Indian population...
  28. Joung H, Kim B, Park H, Lee K, Kim H, Sim H, et al. Fermented Moringa oleifera Decreases Hepatic Adiposity and Ameliorates Glucose Intolerance in High-Fat Diet-Induced Obese Mice. J Med Food. 2017;20:439-447 pubmed publisher
    ..oleifera extract (NFM), or FM for 10 weeks...
  29. Shangpliang H, Rai R, Keisam S, Jeyaram K, Tamang J. Bacterial community in naturally fermented milk products of Arunachal Pradesh and Sikkim of India analysed by high-throughput amplicon sequencing. Sci Rep. 2018;8:1532 pubmed publisher
    Naturally fermented milk (NFM) products are popular ethnic fermented foods in Arunachal Pradesh and Sikkim states of India. The present study is the first to have documented the bacterial community in 54 samples of NFM products viz...
  30. Campos Melo D, Hawley Z, Strong M. Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs. Mol Brain. 2018;11:43 pubmed publisher
    ..The stoichiometry of NF protein subunits (NFL, NFM and NFH) has to be tightly controlled to avoid the formation of NF neuronal cytoplasmic inclusions (NCIs), axonal ..
  31. Hu J, Feng A, Chang B, Lin C, Mong K. A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation. Org Biomol Chem. 2017;15:5345-5356 pubmed publisher
    ..Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation...
  32. Yuan A, Sershen H, Veeranna -, Basavarajappa B, Kumar A, Hashim A, et al. Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo. Mol Psychiatry. 2015;20:986-94 pubmed publisher
    ..Deletion of NFM in mice, but not the deletion of any other NF subunit, amplifies dopamine D1-receptor-mediated motor responses to ..
  33. Kang M, Law Davis S, Balaratnasingam C, Yu D. Sectoral variations in the distribution of axonal cytoskeleton proteins in the human optic nerve head. Exp Eye Res. 2014;128:141-50 pubmed publisher
    ..The axonal cytoskeleton was studied using antibodies to neurofilament light (NFL), neurofilament medium (NFM), neurofilament heavy (NFH), phosphorylated NFH (NFHp), microtubule associated protein-1 (MAP-1) and tubulin...
  34. Ammirati E, Cipriani M, Lilliu M, Sormani P, Varrenti M, Raineri C, et al. Survival and Left Ventricular Function Changes in Fulminant Versus Nonfulminant Acute Myocarditis. Circulation. 2017;136:529-545 pubmed publisher
    ..patients with fulminant myocarditis (FM) might have better outcome than those with acute nonfulminant myocarditis (NFM)...
  35. Wang N, Cai M, Yang X, Yang Y. Electret nanofibrous membrane with enhanced filtration performance and wearing comfortability for face mask. J Colloid Interface Sci. 2018;530:695-703 pubmed publisher
    ..filter medium consisting of electret polyethersulfone/barium titanate nanofibrous membrane (PES/BaTiO3 NFM) integrated on a nonwoven polypropylene substrate was developed...
  36. Krämer M, Ribeiro D, Arsenian Henriksson M, Deller T, Rohrer H. Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling. J Neurosci. 2016;36:10425-10439 pubmed
    ..SKP2 inhibition supports a function for SKP2 in the maintained neuroblast proliferation downstream of MYCN/ALK, which may represent an early step toward tumorigenesis. ..
  37. Monteiro N, Martins M, Martins A, Fonseca N, Moreira J, Reis R, et al. Antibacterial activity of chitosan nanofiber meshes with liposomes immobilized releasing gentamicin. Acta Biomater. 2015;18:196-205 pubmed publisher
    Chitsan (Ch) nanofiber mesh (NFM) is a material with natural characteristics favoring its use in human wound dressing...
  38. El Moghazy A, Zhao C, Istamboulie G, Amaly N, Si Y, Noguer T, et al. Ultrasensitive label-free electrochemical immunosensor based on PVA-co-PE nanofibrous membrane for the detection of chloramphenicol residues in milk. Biosens Bioelectron. 2018;117:838-844 pubmed publisher
    ..The performance of the PVA-co-PE nanofiber membrane (PVA-co-PE NFM) on the electrode was compared with a PVA-co-PE casted membrane (PVA-co-PE CM), necessary fabrication steps and ..
  39. Cortínez L, Anderson B, Holford N, Puga V, De La Fuente N, Auad H, et al. Dexmedetomidine pharmacokinetics in the obese. Eur J Clin Pharmacol. 2015;71:1501-8 pubmed publisher
    ..Population pharmacokinetic modeling was undertaken to investigate fat free mass (FFM) and normal fat mass (NFM) as size descriptors of volumes and clearances using non-linear mixed effects modeling...
  40. Senthamizhan A, Balusamy B, Aytac Z, Uyar T. Ultrasensitive electrospun fluorescent nanofibrous membrane for rapid visual colorimetric detection of H2O2. Anal Bioanal Chem. 2016;408:1347-55 pubmed publisher
    ..The provision of AuNC coupled to NFM has proven to be advantageous for facile and quick visualization of the obtained results, permitting instant, ..
  41. Liu R, Liu B, Zhu L, He Z, Ju J, Lan H, et al. Effects of fluoride on the removal of cadmium and phosphate by aluminum coagulation. J Environ Sci (China). 2015;32:118-25 pubmed publisher
    ..e., the formation of Al(OH)nFm. Al-F complex formation inhibits Al hydrolysis and increases residual Al levels, and a more significant increase ..
  42. Heimfarth L, da Silva Ferreira F, Pierozan P, Loureiro S, Mingori M, Moreira J, et al. Calcium signaling mechanisms disrupt the cytoskeleton of primary astrocytes and neurons exposed to diphenylditelluride. Biochim Biophys Acta. 2016;1860:2510-2520 pubmed publisher
    ..caused hyperphosphorylation of glial fibrillary acidic protein (GFAP), vimentin and neurofilament subunits (NFL, NFM and NFH) from primary astrocytes and neurons, respectively...
  43. Chen C, Chen S, Shalumon K, Chen J. Prevention of peritendinous adhesions with electrospun polyethylene glycol/polycaprolactone nanofibrous membranes. Colloids Surf B Biointerfaces. 2015;133:221-30 pubmed publisher
    ..we fabricated electrospun composite poly(ethylene glycol) (PEG)/poly(caprolactone) (PCL) nanofibrous membrane (NFM) to prevent peritendinous adhesions, which could act as a barrier between the tendon and surrounding tissues, ..
  44. Deng Y, Han Q, Shen F, Chen M, Zeng H. [Effect of axonal developmental disorders in the corpus callosum on the neurological function after birth in septic neonatal rats]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016;28:683-7 pubmed publisher
    ..Western Blot were used to observe the expression of neurofilament heavy chain (NFH), neurofilament medium chain (NFM) and neurofilament light chain (NFL) in the corpus callosum...
  45. George C, Gontier G, Lacube P, Francois J, Holzenberger M, Aid S. The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons. Brain. 2017;140:2012-2027 pubmed publisher
    ..One of the genes consistently highlighted in genome-wide comparison was the neurofilament medium polypeptide Nefm...
  46. KHANDAKER M, Riahinezhad S, Williams W, Wolf R. Microgroove and Collagen-poly(ε-caprolactone) Nanofiber Mesh Coating Improves the Mechanical Stability and Osseointegration of Titanium Implants. Nanomaterials (Basel). 2017;7: pubmed publisher
    The effect of depositing a collagen (CG)-poly-ε-caprolactone (PCL) nanofiber mesh (NFM) at the microgrooves of titanium (Ti) on the mechanical stability and osseointegration of the implant with bone was investigated using a rabbit model...
  47. Lee E, Rath P, Liu J, Ryu D, Pei L, Noonepalle S, et al. Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells. J Genet Genomics. 2015;42:355-71 pubmed publisher
    ..The results from this study demonstrate that GSCs possess unique epigenetic signatures that may play important roles in the pathogenesis of GBM. ..
  48. Singh V, Singh L, Vasudevan M, Chattopadhyay I, Borthakar B, Rai A, et al. Esophageal Cancer Epigenomics and Integrome Analysis of Genome-Wide Methylation and Expression in High Risk Northeast Indian Population. OMICS. 2015;19:688-99 pubmed publisher
    ..In conclusion, we recommend that the circulatory proteins IL22RA2, TNFSF13B, SERPINA4, and TAC3 in serum of patients and disease-free healthy controls can be examined in the future as putative noninvasive biomarkers. ..
  49. Matthijs S, Brandt N, Ongena M, Achouak W, Meyer J, Budzikiewicz H. Pyoverdine and histicorrugatin-mediated iron acquisition in Pseudomonas thivervalensis. Biometals. 2016;29:467-85 pubmed publisher
    ..thivervalensis with the 17 receptors of its phylogenetic neighbor, P. brassicacearum subsp. brassicacearum NFM 421, showed that NFM 421 shares the same set of receptors with LMG 21626(T), including the histicorrugatin receptor...
  50. Her Q, Seger D, Amato M, Beeler P, Dalleur O, Slight S, et al. Development of an algorithm to assess appropriateness of overriding alerts for nonformulary medications in a computerized prescriber-order-entry system. Am J Health Syst Pharm. 2016;73:e34-45 pubmed publisher
    ..appropriateness of physician overrides of clinical decision support alerts triggered by nonformulary medication (NFM) requests is described...
  51. Subbarao R, Ullah I, Kim E, Jang S, Lee W, Jeon R, et al. Characterization and evaluation of neuronal trans-differentiation with electrophysiological properties of mesenchymal stem cells isolated from porcine endometrium. Int J Mol Sci. 2015;16:10934-51 pubmed publisher
    ..of EMSCs exhibited distinctive dendritic morphology with axon projections and neuronal specific genes, NFM, NGF, MBP, NES, B3T and MAP2 and proteins, B3T, NFM, NGF, and TRKA were positively expressed in neuronal ..
  52. Wang C, Szaro B. Post-transcriptional regulation mediated by specific neurofilament introns in vivo. J Cell Sci. 2016;129:1500-11 pubmed publisher
    ..These results expand our knowledge of intron-mediated gene expression to encompass neurofilaments, indicating an additional layer of complexity in the control of a cytoskeletal gene needed for developing and maintaining healthy axons. ..
  53. Reis K, Heimfarth L, Pierozan P, Ferreira F, Loureiro S, Fernandes C, et al. High postnatal susceptibility of hippocampal cytoskeleton in response to ethanol exposure during pregnancy and lactation. Alcohol. 2015;49:665-74 pubmed publisher
    ..fibrillary acidic protein (GFAP), and neurofilament (NF) subunits of low, medium, and high molecular weight (NFL, NFM, and NFH, respectively) in 9- and 21-day-old pups...
  54. Blom W, Koppenol W, Schuring E, Abrahamse S, Arnaudov L, Mela D, et al. Sustained satiety induced by food foams is independent of energy content, in healthy adults. Appetite. 2016;97:64-71 pubmed publisher
    ..compared to a very low energy food foam (VLEF, 36 kJ/400 mL) and 2 alternative normal energy foams (NEF2 and NEF3) testing possible effects of compositional differences other than energy (i.e. emulsifier and carbohydrate source)...
  55. Tzekov R, Dawson C, Orlando M, Mouzon B, Reed J, Evans J, et al. Sub-Chronic Neuropathological and Biochemical Changes in Mouse Visual System after Repetitive Mild Traumatic Brain Injury. PLoS ONE. 2016;11:e0153608 pubmed publisher
    ..This will allow future identification of therapeutic targets for improving the visual consequences of r-mTBI. ..
  56. Yuan A, Nixon R. Specialized roles of neurofilament proteins in synapses: Relevance to neuropsychiatric disorders. Brain Res Bull. 2016;126:334-346 pubmed publisher
    Neurofilaments are uniquely complex among classes of intermediate filaments in being composed of four subunits (NFL, NFM, NFH and alpha-internexin in the CNS) that differ in structure, regulation, and function...
  57. Heng B, Gong T, Wang S, Lim L, Wu W, Zhang C. Decellularized Matrix Derived from Neural Differentiation of Embryonic Stem Cells Enhances the Neurogenic Potential of Dental Follicle Stem Cells. J Endod. 2017;43:409-416 pubmed publisher
    ..Expression of early/intermediate (Musashi1, PAX6, NSE, and βIII-tubulin) and mature/late (NGN2, NeuN, NFM, and MASH1) neural markers by DFSCs was analyzed at the 7-, 14-, and 21-day time points with quantitative real-time ..
  58. Kamboj S, Rana V. Quality-by-design based development of a self-microemulsifying drug delivery system to reduce the effect of food on Nelfinavir mesylate. Int J Pharm. 2016;501:311-25 pubmed publisher
    Poor aqueous solubility and moderate permeability of Nelfinavir mesylate (NFM) leads to high variability in absorption after oral administration...
  59. Wang Z, Lim B. Mixed cellulose ester filter as a separator for air-diffusion cathode microbial fuel cells. Environ Technol. 2017;38:979-984 pubmed publisher
    ..7?±?18.7?mW/m2, which was comparable to 770.9?±?35.9?mW/m2 of MFC with Nafion membrane (NFM) as a separator. Long-term examination demonstrated a more stable performance of the MCEF-MFC than NFM-MFC...
  60. You M, Yan X, Zhang J, Wang X, He X, Yu M, et al. Colorimetric Humidity Sensors Based on Electrospun Polyamide/CoCl2 Nanofibrous Membranes. Nanoscale Res Lett. 2017;12:360 pubmed publisher
    ..Owing to the above double sensitive mechanism on RH, the PA66/CoCl2 composite NFM may show great potential applications from meticulous to coarse.
  61. Zelman B, Melgar M, Larson E, Phillips A, Shretta R. Global fund financing to the 34 malaria-eliminating countries under the new funding model 2014-2017: an analysis of national allocations and regional grants. Malar J. 2016;15:118 pubmed publisher
    ..In 2011, the GFATM transitioned to a new funding model (NFM), which prioritizes grants to high burden, lower income countries...
  62. Dahal B, NandaKafle G, Perkins L, Brözel V. Diversity of free-Living nitrogen fixing Streptomyces in soils of the badlands of South Dakota. Microbiol Res. 2017;195:31-39 pubmed publisher
    ..Diazotrophs were isolated on solid nitrogen free medium (NFM) under hypoxic conditions, and their16S rRNA and nifH genes sequenced...
  63. Kruger R, Fischer C, Schulte T, Strauss K, Muller T, Woitalla D, et al. Mutation analysis of the neurofilament M gene in Parkinson's disease. Neurosci Lett. 2003;351:125-9 pubmed
    b>Neurofilament M, a major component of Lewy bodies, represents an interesting candidate in the pathogenesis of Parkinson's disease (PD). We performed detailed mutation analyses of the NF-M gene in 322 familial and sporadic PD patients...
  64. Garcia M, Singleton A, Hernandez D, Ward C, Evey C, Sapp P, et al. Mutations in neurofilament genes are not a significant primary cause of non-SOD1-mediated amyotrophic lateral sclerosis. Neurobiol Dis. 2006;21:102-9 pubmed
    ..Thus, mutations in neurofilaments are possible risk factors that may contribute to pathogenesis in ALS in conjunction with one or more additional genetic or environmental factors, but are not significant primary causes of ALS. ..
  65. Carvalho R, da Silva Ferreira F, Heimfarth L, Pierozan P, Fernandes C, Pessoa Pureur R. Acute Hyperammonemia Induces NMDA-Mediated Hypophosphorylation of Intermediate Filaments Through PP1 and PP2B in Cerebral Cortex of Young Rats. Neurotox Res. 2016;30:138-49 pubmed publisher
    ..and vimentin) and neurons (neurofilament subunits of low, middle, and high molecular weight, respectively: NFL, NFM, and NFH) from cerebral cortex of 21-day-old rats...
  66. Chin T, Harding S, Eagles P. Characterization of two proteolytically derived soluble polypeptides from the neurofilament triplet components NFM and NFH. Biochem J. 1989;264:53-60 pubmed
    ..purified to homogeneity the regions derived by chymotryptic digestion of the ox neurofilament polypeptides NFH and NFM; the regions, called M1 and M2, are thought to form part of the projecting sidearms of mammalian neurofilaments [..
  67. Myers M, Lazzarini R, Lee V, Schlaepfer W, Nelson D. The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. EMBO J. 1987;6:1617-26 pubmed
    ..This finding suggests a common origin of the neurofilament subunits, whose evolutionary relationship to other intermediate filament genes is uncertain. ..
  68. Dong D, Xu Z, Chevrier M, Cotter R, Cleveland D, Hart G. Glycosylation of mammalian neurofilaments. Localization of multiple O-linked N-acetylglucosamine moieties on neurofilament polypeptides L and M. J Biol Chem. 1993;268:16679-87 pubmed
    ..Specific identification of these O-GlcNAc attachment sites has set the stage for more detailed mutagenic analysis of O-GlcNAc functions on neurofilaments. ..
  69. Bhaskar K, Shareef M, Sharma V, Shetty A, Ramamohan Y, Pant H, et al. Co-purification and localization of Munc18-1 (p67) and Cdk5 with neuronal cytoskeletal proteins. Neurochem Int. 2004;44:35-44 pubmed
  70. DeGiorgis J, Jaffe H, Moreira J, Carlotti C, Leite J, Pant H, et al. Phosphoproteomic analysis of synaptosomes from human cerebral cortex. J Proteome Res. 2005;4:306-15 pubmed
    ..The study shows that new phosphoproteomic strategies can be used to analyze subcellular fractions from small amounts of tissue for the identification of phosphorylated residues for research and potentially for diagnostic purposes. ..
  71. Lüdemann N, Clement A, Hans V, Leschik J, Behl C, Brandt R. O-glycosylation of the tail domain of neurofilament protein M in human neurons and in spinal cord tissue of a rat model of amyotrophic lateral sclerosis (ALS). J Biol Chem. 2005;280:31648-58 pubmed
  72. Owen J, Delany M, Cardona C, Bickford A, Mullens B. Host inflammatory response governs fitness in an avian ectoparasite, the northern fowl mite (Ornithonyssus sylviarum). Int J Parasitol. 2009;39:789-99 pubmed
    ..This study focused on an ectoparasite of birds--the northern fowl mite (NFM) (Ornithonyssus sylviarum)...
  73. Rudrabhatla P, Jaffe H, Pant H. Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs. FASEB J. 2011;25:3896-905 pubmed publisher
    ..In corresponding matched control preparations of PHF/NFTs, none of these phosphorylated neuronal cytoskeletal proteins were found. These studies independently demonstrate that NF proteins are an integral part of NFTs in AD brains. ..
  74. Chang J, Mukerjee R, Bagashev A, Del Valle L, Chabrashvili T, Hawkins B, et al. HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs. J Biol Chem. 2011;286:41125-34 pubmed publisher
    ..Therefore, we conclude that deregulation of neuronal functions by HIV-1 Tat protein is miRNA-dependent...
  75. Jones A, Mowry B, McLean D, Mantzioris B, Pender M, Greer J. Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia. J Neuroimmunol. 2014;269:68-75 pubmed publisher
    ..predominantly targeted microfilaments, intermediate filaments or neurofilaments, particularly neurofilament medium (NFM), which is a dopamine receptor interacting protein...
  76. Timani K, Liu Y, Suvannasankha A, He J. Regulation of ubiquitin-proteasome system-mediated Tip110 protein degradation by USP15. Int J Biochem Cell Biol. 2014;54:10-9 pubmed publisher
    ..Interestingly, USP15 knockdown restored hTip110 protein expression in Tg MEF and USP15 expression had little effects. Taken together, these results provide insights into the regulatory mechanism of human Tip110 degradation by USP15. ..
  77. Josephson M, Aliani R, Norris M, Ochs M, Gujar M, Lundquist E. The Caenorhabditis elegans NF2/Merlin Molecule NFM-1 Nonautonomously Regulates Neuroblast Migration and Interacts Genetically with the Guidance Cue SLT-1/Slit. Genetics. 2017;205:737-748 pubmed publisher
    ..In a screen for genes required for AQR and PQR migration, we identified an allele of nfm-1, which encodes a molecule similar to vertebrate NF2/Merlin, an important tumor suppressor in humans...
  78. Ruas R, Pinto A, Nuak J, Sarmento A, Abreu C. Non-falciparum malaria imported mainly from Africa: a review from a Portuguese hospital. Malar J. 2017;16:298 pubmed publisher
    Non-falciparum malaria (NFM) has been reported to be responsible for around 25% of imported malaria cases in Europe but is often neglected due to its less severe clinical course when compared to Plasmodium falciparum...
  79. Mahmoudifard M, Soleimani M, Vossoughi M. Ammonia plasma-treated electrospun polyacrylonitryle nanofibrous membrane: the robust substrate for protein immobilization through glutaraldhyde coupling chemistry for biosensor application. Sci Rep. 2017;7:9441 pubmed publisher
    The surface of polyacrylonitrile electrospun nanofibrous membrane (PAN NFM) was aminated by the ammonia plasma treatment. The content of amine groups has been estimated for different time of plasma treatment...
  80. Liu M, Xu P, Guan Z, Qian X, Dockery P, FitzGerald U, et al. Ulk4 deficiency leads to hypomyelination in mice. Glia. 2018;66:175-190 pubmed publisher
    ..This is the first evidence demonstrating that ULK4 is a crucial regulator of myelination, and ULK4 may therefore become a novel therapeutic target for hypomyelination diseases. ..
  81. Mirza Z, Rajeh N. Identification Of Electrophysiological Changes In Alzheimer's Disease: A Microarray Based Transcriptomics And Molecular Pathway Analysis Study. CNS Neurol Disord Drug Targets. 2017;: pubmed publisher
  82. Lee V, Otvos L, Carden M, Hollosi M, Dietzschold B, Lazzarini R. Identification of the major multiphosphorylation site in mammalian neurofilaments. Proc Natl Acad Sci U S A. 1988;85:1998-2002 pubmed
    ..e., MAP2 and tau. ..
  83. Wang Y, Wang Q, Wang J. [Detection of level and mutation of neurofilament mRNA in Alzheimer's disease]. Zhonghua Yi Xue Za Zhi. 2002;82:519-22 pubmed
    ..No NF-L mutation was found in the samples examined. The increase of neurofilament protein observed in the brains of AD patients is related neither to increased gene transcription nor to mutation of NF mRNA. ..
  84. Qu K, Lu Y, Lin N, Singh R, Xu X, Payan D, et al. Computational and experimental studies on human misshapen/NIK-related kinase MINK-1. Curr Med Chem. 2004;11:569-82 pubmed
    ..Further medicinal chemistry compound structure optimization and kinase assays are underway. ..
  85. Perez Olle R, Lopez Toledano M, Liem R. The G336S variant in the human neurofilament-M gene does not affect its assembly or distribution: importance of the functional analysis of neurofilament variants. J Neuropathol Exp Neurol. 2004;63:759-74 pubmed
    ..Our data suggest that if the G336S variant is involved in the development of PD, it does not appear to be due to defects in the assembly and distribution of NFs. ..
  86. Leermakers F, Zhulina E. How the projection domains of NF-L and alpha-internexin determine the conformations of NF-M and NF-H in neurofilaments. Eur Biophys J. 2010;39:1323-34 pubmed publisher
    ..Replacing all L-tails by alpha-projections destroys the substructure of the NF corona and this alters the NF response to the phosphorylation of long tails. ..
  87. Edalat H, Hajebrahimi Z, Pirhajati V, Tavallaei M, Movahedin M, Mowla S. Exogenous Expression of Nt-3 and TrkC Genes in Bone Marrow Stromal Cells Elevated the Survival Rate of the Cells in the Course of Neural Differentiation. Cell Mol Neurobiol. 2017;37:1187-1194 pubmed publisher
    ..The expression of neural markers (i.e., NFM, and NeuroD1) was augmented in cotransfected BMSCs, compared to the control ones, after neural induction...
  88. Hiday A, Edler M, Salek A, Morris C, Thang M, Rentz T, et al. Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction. Neural Plast. 2017;2017:4153076 pubmed publisher
    ..Our data determine mechanisms that regulate, and putative consequences of, pathological changes in the association of spinophilin with NF-M that are observed in animal models of PD. ..
  89. Blanchfield L, Sabatino J, Lawrence L, Evavold B. NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease. J Immunol. 2017;199:2680-2691 pubmed publisher
    ..oligodendrocyte glycoprotein epitope 35-55 (MOG35-55) and neurofilament medium protein epitope 15-35 (NFM15-35)...
  90. Zhang Y, Guan J, Wang X, Yu J, Ding B. Balsam-Pear-Skin-Like Porous Polyacrylonitrile Nanofibrous Membranes Grafted with Polyethyleneimine for Postcombustion CO2 Capture. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    ..This work paves the way for fabricating NFM-based solid adsorption materials endowed with a porous structure applied to efficient postcombustion CO2 ..
  91. Rehman M, Khan M, Khan W, Shafique M, Khan M. Fabrication of Niclosamide loaded solid lipid nanoparticles: in vitro characterization and comparative in vivo evaluation. Artif Cells Nanomed Biotechnol. 2017;:1-9 pubmed publisher
    ..b>NFM-3 showed particle size 204.2?±?2.2?nm, polydispersity index 0.328?±?0.02 and zeta potential -33.16?±?2?mV...
  92. El Ayachi I, Zhang J, Zou X, Yu Z, Wei W, O Connell K, et al. Human dental stem cell derived transgene-free iPSCs generate functional neurons via embryoid body-mediated and direct induction methods. J Tissue Eng Regen Med. 2017;: pubmed publisher
    ..At late stage of differentiation, all 5 genes tested, nestin, ?III-tubulin, NFM, GFAP and NaV were positive in many cells in cultures...