Gene Symbol: NAPA
Description: NSF attachment protein alpha
Alias: SNAPA, alpha-soluble NSF attachment protein, N-ethylmaleimide-sensitive factor attachment protein, alpha, alpha-SNAP
Species: human
Products:     NAPA

Top Publications

  1. Hanson P, Otto H, Barton N, Jahn R. The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin. J Biol Chem. 1995;270:16955-61 pubmed
    ..This suggests that the conformational change normally induced by NSF in syntaxin depends on an interaction between carboxyl- and amino-terminal domains of syntaxin. ..
  2. Whiteheart S, Griff I, Brunner M, Clary D, Mayer T, Buhrow S, et al. SNAP family of NSF attachment proteins includes a brain-specific isoform. Nature. 1993;362:353-5 pubmed
  3. Rabouille C, Kondo H, Newman R, Hui N, Freemont P, Warren G. Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro. Cell. 1998;92:603-10 pubmed
    ..p47 also mediates the binding of p97 to syntaxin 5 and so plays an analogous role to alpha-SNAP, which mediates the binding of NSF. ..
  4. Wong S, Xu Y, Zhang T, Hong W. Syntaxin 7, a novel syntaxin member associated with the early endosomal compartment. J Biol Chem. 1998;273:375-80 pubmed
  5. Nakajima K, Hirose H, Taniguchi M, Kurashina H, Arasaki K, Nagahama M, et al. Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. EMBO J. 2004;23:3216-26 pubmed
    ..Indeed, overexpression of alpha-SNAP markedly delayed staurosporine-induced apoptosis. Our results shed light on possible crosstalk between apparently independent cellular events, apoptosis and ER membrane fusion. ..
  6. Tang B, Tan A, Lim L, Lee S, Low D, Hong W. Syntaxin 12, a member of the syntaxin family localized to the endosome. J Biol Chem. 1998;273:6944-50 pubmed
    ..The cDNA we have cloned apparently corresponded to three previously described expressed sequence tags named as syntaxins 12, 13, and 14, respectively. We therefore propose to retain the name syntaxin 12 for this protein. ..
  7. Andreeva A, Kutuzov M, Vaiskunaite R, Profirovic J, Meigs T, Predescu S, et al. G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. J Biol Chem. 2005;280:30376-83 pubmed
  8. Barnard R, Morgan A, Burgoyne R. Stimulation of NSF ATPase activity by alpha-SNAP is required for SNARE complex disassembly and exocytosis. J Cell Biol. 1997;139:875-83 pubmed
    ..These findings imply that alpha-SNAP stimulation of NSF ATPase activity may be required for 20S complex disassembly and for the alpha-SNAP stimulation of exocytosis. ..
  9. Wang G, Maier R. A novel DNA-binding protein plays an important role in Helicobacter pylori stress tolerance and survival in the host. J Bacteriol. 2015;197:973-82 pubmed publisher
    ..oxidative stress conditions revealed a number of important antioxidant protein differences; SodB, Tpx, TrxR, and NapA, as well as the peptidoglycan deacetylase PgdA, were significantly less expressed in the Δhp119 mutant than in ..

More Information

Publications139 found, 100 shown here

  1. Castillo A, Kramer N, Schwartz C, Miles J, DuPont B, Rosenfeld J, et al. 19q13.32 microdeletion syndrome: three new cases. Eur J Med Genet. 2014;57:654-8 pubmed publisher a deletion of some combination of the 20-23 genes in common between these two patients, especially NPAS1, NAPA, ARHGAP35, SLC8A2, DHX34, MEIS3, and ZNF541...
  2. Brandon E, Szul T, Alvarez C, Grabski R, Benjamin R, Kawai R, et al. On and off membrane dynamics of the endoplasmic reticulum-golgi tethering factor p115 in vivo. Mol Biol Cell. 2006;17:2996-3008 pubmed
    ..In agreement, biochemical studies show increased p115 recruitment to membranes in the presence of NSF and alpha-SNAP. Our data support a model in which recruitment of tethers is directly regulated by the assembly status of SNAREs. ..
  3. Whitmore L, Weems M, Allen L. Cutting Edge: Helicobacter pylori Induces Nuclear Hypersegmentation and Subtype Differentiation of Human Neutrophils In Vitro. J Immunol. 2017;198:1793-1797 pubmed publisher
    ..pylori contact as well as transcription and both host and bacterial protein synthesis, but not urease, NapA, VacA, CagA, or CagT...
  4. Gui M, Chen Q, Ma T, Zheng M, Ni J. Effects of heavy metals on aerobic denitrification by strain Pseudomonas stutzeri PCN-1. Appl Microbiol Biotechnol. 2017;101:1717-1727 pubmed publisher
    ..sensitivity of denitrifying gene to heavy metals was similar in order of nosZ > nirS ? cnorB > napA. This study is of significance in understanding the potential application of aerobic denitrifying bacteria in ..
  5. Du C, Cui C, Qiu S, Shi S, Li A, Ma F. Nitrogen removal and microbial community shift in an aerobic denitrification reactor bioaugmented with a Pseudomonas strain for coal-based ethylene glycol industry wastewater treatment. Environ Sci Pollut Res Int. 2017;24:11435-11445 pubmed publisher
    ..The napA gene analysis indicated that the decrease in nitrate and nitrite removal happened when abundance of Pseudomonas was ..
  6. Ullah A, Dutta D, Fliegel L. Expression and characterization of the SOS1 Arabidopsis salt tolerance protein. Mol Cell Biochem. 2016;415:133-43 pubmed publisher
    ..An analysis of SOS1 predicted a topology of 13 transmembrane segments, distinct from E. coli NhaA but similar to the Na(+)/H(+) exchangers Methanocaldococcus jannaschii NhaP1 and Thermus thermophile NapA.
  7. Karakullukcu A, Tokman H, Nepesov S, Demirci M, Saribas S, Vehid S, et al. The protective role of Helicobacter pylori neutrophil-activating protein in childhood asthma. Allergol Immunopathol (Madr). 2017;45:521-527 pubmed publisher
    ..Different napA expression levels may be caused by different endogenous napA gene expression or different environmental conditions.
  8. Wang H, Deng N, Wu D, Hu S, Kou M. Long-term net transformation and quantitative molecular mechanisms of soil nitrogen during natural vegetation recovery of abandoned farmland on the Loess Plateau of China. Sci Total Environ. 2017;607-608:152-159 pubmed publisher
    ..Specifically, Ra was controlled by AOA-amoA, AOB-amoA, and nxrA; Rn was governed by napA, narG, nirK, nirS, and nosZ; and Rm was controlled by nifH, apr, AOA-amoA, AOB-amoA, nirS, and nirK.
  9. Wang D, Li T, Huang K, He X, Zhang X. Roles and correlations of functional bacteria and genes in the start-up of simultaneous anammox and denitrification system for enhanced nitrogen removal. Sci Total Environ. 2019;655:1355-1363 pubmed publisher
    ..Moreover, the overwhelming dominance of narG v.s. napA revealed the crucial roles of respiratory nitrate reduction in the bioreactors...
  10. Wang H, Deng N, Wu D, Hu S. Quantitative response relationships between net nitrogen transformation rates and nitrogen functional genes during artificial vegetation restoration following agricultural abandonment. Sci Rep. 2017;7:7752 pubmed publisher
    ..that Ra was collectively controlled by AOA-amoA and Archaea; Rd was jointly governed by narG, napA, nxrA, and bacreria; and Rm was jointly controlled by napA, narG, nirK, nirS, norB, nosZ, and nxrA.
  11. Shu D, He Y, Yue H, Wang Q. Microbial structures and community functions of anaerobic sludge in six full-scale wastewater treatment plants as revealed by 454 high-throughput pyrosequencing. Bioresour Technol. 2015;186:163-72 pubmed publisher bacteria, anammox bacteria, NOB (Nitrobacter, Nitrospira), AOA amoA, AOB amoA, nosZ, nirS, nirK, narG, napA, nrfA, mcrA and dsrA. Multivariate linear regression analysis indicated that AOA might be mixotrophic...
  12. Wang H, Ji G, Bai X. Enhanced long-term ammonium removal and its ranked contribution of microbial genes associated with nitrogen cycling in a lab-scale multimedia biofilter. Bioresour Technol. 2015;196:57-64 pubmed publisher
    ..6%)>partial denitrification (nirS, nirK) and anammox (37.8%)>anammox and partial denitrification (narG, napA) (12.6%). Specifically, NH4(+)-N removal was significantly inhibited by NO2(-)-N accumulation in the system (-21...
  13. Zhang Y, Ji G, Wang R. Drivers of nitrous oxide accumulation in denitrification biofilters with low carbon:nitrogen ratios. Water Res. 2016;106:79-85 pubmed publisher the biofilters, and the key drivers of the N2O accumulation rates were qnorB/nirK, nosZ/(narG + napA), amx/(nirS + nirK), narG/bacteria and qnorB/bacteria...
  14. Su J, Gao C, Huang T, Bai X, Liang D, He L. Characterization of the Cd(II) and nitrate removal by bacterium Acinetobacter sp. SZ28 under different electron donor conditions. Environ Sci Pollut Res Int. 2019;26:12698-12708 pubmed publisher
    ..Sequence amplification identified the presence of the nitrate reductase gene (napA) and Mn(II)-oxide gene (cumA) in strain SZ28...
  15. Chen D, Yang K, Wei L, Wang H. Microbial community and metabolism activity in a bioelectrochemical denitrification system under long-term presence of p-nitrophenol. Bioresour Technol. 2016;218:189-95 pubmed publisher
    ..The abundances of the denitrifying genes nirS, nirK, napA, and narG all presented decreased trends with increasing PNP...
  16. He S, Ding L, Pan Y, Hu H, Ye L, Ren H. Effect of hydraulic retention time on nitrogen removal and functional gene quantity/transcription in biochar packed reactors at 5 °C: A control-strategy study. Bioresour Technol. 2018;264:400-405 pubmed publisher
    ..02), and effluent DTN had a negative correlation relation with PHB (p < 0.01), the relative abundance of napA (p = 0.01), and the transcriptional quantity of nirS (p = 0.14) and nxrA (p = 0.03).
  17. Lee C, Kang H, Hjelm A, Qureshi A, Nji E, Choudhury H, et al. MemStar: a one-shot Escherichia coli-based approach for high-level bacterial membrane protein production. FEBS Lett. 2014;588:3761-9 pubmed publisher
    ..With MemStar, we have been able to obtain new structural information for several transporters, including the sodium/proton antiporter NapA.
  18. Jeong Y, Balla A, Chun K, Chung S, Maeng H. Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats. Pharmaceutics. 2019;11: pubmed publisher
    ..demonstrated that cimetidine decreased the clearance of procainamide (PA) and/or N-acetylprocainamide (NAPA; the primary metabolite of PA) resulting in the increased systemic exposure and the decrease of urinary excretion...
  19. Van Horn C, Wu F, Zheng Z, Dai Z, Chen J. Detection of a Single-copy Plasmid, pXFSL21in Xylella fastidiosa Strain Stag's Leap with Two Toxin-Antitoxin Systems Using Next Generation Sequencing. Phytopathology. 2018;: pubmed publisher
    ..In this study, the plasmid status of a highly virulent PD strain, Stag's Leap, originally isolated from Napa Valley, California, was studied using sequencing and bioinformatics tools...
  20. Ginanneschi F, Aretini A, Mondelli M. Relations between sensory symptoms, touch sensation, and sensory neurography in the assessment of the ulnar neuropathy at the elbow. Clin Neurophysiol. 2018;130:199-206 pubmed publisher
    ..Symptoms in the fifth digit, reduction of touch sensation and U5 sensory nerve action potential amplitude (SNAPa) had the highest sensitivity, specificity and predictivity in UNE diagnosis...
  21. Wang H, Han J, Deng N, An S. Effects of the natural restoration time of abandoned farmland in a semiarid region on the soil denitrification rates and abundance and community structure of denitrifying bacteria. Appl Microbiol Biotechnol. 2019;103:1939-1951 pubmed publisher
    ..The total bacterial and napA gene abundances significantly decreased after abandonment (< 9 years) compared to that of farmland and then ..
  22. Simon M, Krause P, Chiappisi L, Noirez L, Gradzielski M. Structural control of polyelectrolyte/microemulsion droplet complexes (PEMECs) with different polyacrylates. Chem Sci. 2019;10:385-397 pubmed publisher
    ..mixtures of cationic oil-in-water (O/W) microemulsion droplets and oppositely charged sodium polyacrylate (NaPA) and determined structure and phase behaviour as a function of the mixing ratio for different droplet sizes and ..
  23. Lin L, Harnly J. Phenolic component profiles of mustard greens, yu choy, and 15 other brassica vegetables. J Agric Food Chem. 2010;58:6850-7 pubmed publisher
    ..bok choy, bok choy sum, Taiwan bok choy, Shanghai bok choy, baby Shanghai bok choy, rapini broccoli, turnip green, napa, and baby napa...
  24. Mauffret A, Baran N, Joulian C. Effect of pesticides and metabolites on groundwater bacterial community. Sci Total Environ. 2017;576:879-887 pubmed publisher fingerprinting techniques (CE-SSCP), gene presence (atzA/B/C/D/E/F and amoA genes) and abundance (16S RNA, napA and narG genes)...
  25. Wang D, He Y, Zhang X. A comprehensive insight into the functional bacteria and genes and their roles in simultaneous denitrification and anammox system at varying substrate loadings. Appl Microbiol Biotechnol. 2019;103:1523-1533 pubmed publisher
    ..Quantitative real-time PCR showed that the anammox genes (hzsA, hzsB, and hzo) and denitrifying genes (narG, napA, and nirS) demonstrated high abundance in the optimized bioreactor...
  26. Dow J, Grahl S, Ward R, Evans R, Byron O, Norman D, et al. Characterization of a periplasmic nitrate reductase in complex with its biosynthetic chaperone. FEBS J. 2014;281:246-60 pubmed publisher
    ..The catalytic subunit of the periplasmic nitrate reductase NapA contains two types of redox cofactor and is exported across the cytoplasmic membrane by the twin-arginine protein ..
  27. Patiño Ruiz M, Dwivedi M, Calinescu O, Karabel M, Padan E, Fendler K. Replacement of Lys-300 with a glutamine in the NhaA Na+/H+ antiporter of Escherichia coli yields a functional electrogenic transporter. J Biol Chem. 2019;294:246-256 pubmed publisher
    ..that substitution of the equivalent residue, Lys-305, of a related Na+/H+ antiporter, NapA from Thermus thermophilus, renders the transporter electroneutral...
  28. Stoppoloni D, Politi L, Leopizzi M, Gaetani S, Guazzo R, Basciani S, et al. Effect of glucosamine and its peptidyl-derivative on the production of extracellular matrix components by human primary chondrocytes. Osteoarthritis Cartilage. 2015;23:103-13 pubmed publisher
    ..effects of Glucosamine (GlcN) and its peptidyl-derivative, 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy-β-D-glucose (NAPA), on extracellular matrix (ECM) synthesis in human primary chondrocytes (HPCs)...
  29. Shakeri R, Malekzadeh R, Nasrollahzadeh D, Pawlita M, Pawilta M, Murphy G, et al. Multiplex H. pylori Serology and Risk of Gastric Cardia and Noncardia Adenocarcinomas. Cancer Res. 2015;75:4876-83 pubmed publisher
    ..Surprisingly, GroEL and NapA were significantly associated with a reduced risk of these tumors...
  30. Zhang Y, Ji G, Wang C, Zhang X, Xu M. Importance of denitrification driven by the relative abundances of microbial communities in coastal wetlands. Environ Pollut. 2019;244:47-54 pubmed publisher
    ..on denitrification potential were mainly mediated by the relative abundances of nosZ/nirS, nirS/(narG + napA) and amoA/nirK...
  31. Shan Y, Lu X, Han Y, Li X, Wang X, Shao C, et al. Helicobacter pylori Outer Membrane Protein 18 (Hp1125) Is Involved in Persistent Colonization by Evading Interferon- γ Signaling. Biomed Res Int. 2015;2015:571280 pubmed publisher
    ..qRT-PCR and western blot analysis revealed reduced expressions of virulence factors CagA and NapA in H. pylori 26695 with IFN-γ treatment, but they were induced in the Δomp18 strain...
  32. Mayeda E, Glymour M, Quesenberry C, Whitmer R. Inequalities in dementia incidence between six racial and ethnic groups over 14 years. Alzheimers Dement. 2016;12:216-24 pubmed publisher
    Reducing racial/ethnic disparities is a primary objective of the National Alzheimer's Plan (NAPA), yet direct comparisons within large samples representing diversity of the United States are lacking...
  33. Nieto N, Salkeld D. Epidemiology and Genetic Diversity of Anaplasma phagocytophilum in the San Francisco Bay Area, California. Am J Trop Med Hyg. 2016;95:50-4 pubmed publisher western black-legged tick populations in 20 recreational areas in California's San Francisco Bay Area (Marin, Napa, San Mateo, Santa Clara, Santa Cruz, and Sonoma counties). Overall, prevalence of A...
  34. He S, Ding L, Pan Y, Hu H, Ye L, Ren H. Nitrogen loading effects on nitrification and denitrification with functional gene quantity/transcription analysis in biochar packed reactors at 5?°C. Sci Rep. 2018;8:9844 pubmed publisher
    ..44?±?0.18, 0.85?±?0.35, and 0.66?±?0.26?mg/L, respectively. The nirS/amoA, nxrA/amoA, and amoA/(narG?+?napA) were deemed to be the markers of ammonium oxidation rate (SAOR), specific nitrite oxidation rate (SNOR), and ..
  35. Zhou S, Zhang Y, Huang T, Liu Y, Fang K, Zhang C. Microbial aerobic denitrification dominates nitrogen losses from reservoir ecosystem in the spring of Zhoucun reservoir. Sci Total Environ. 2019;651:998-1010 pubmed publisher
    ..Specifically, K02567 (napA) represented the main proportion of KOs related to denitrification...
  36. Sparks R, Jenkins J, Fratti R. Use of Surface Plasmon Resonance (SPR) to Determine Binding Affinities and Kinetic Parameters Between Components Important in Fusion Machinery. Methods Mol Biol. 2019;1860:199-210 pubmed publisher
  37. Barszczewski M, Chua J, Stein A, Winter U, Heintzmann R, Zilly F, et al. A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion. Mol Biol Cell. 2008;19:776-84 pubmed
    ..We conclude that alpha-SNAP inhibits exocytosis by binding to the syntaxin SNARE motif and in turn prevents SNARE assembly, revealing an unexpected site of action for alpha-SNAP in the SNARE cycle that drives exocytotic membrane fusion. ..
  38. Li C, Yang J, Wang X, Wang E, Li B, He R, et al. Removal of nitrogen by heterotrophic nitrification-aerobic denitrification of a phosphate accumulating bacterium Pseudomonas stutzeri YG-24. Bioresour Technol. 2015;182:18-25 pubmed publisher
    ..28%, 88.13%, 86.15%, 70.83% and 51.21%. Sequencing and quantitative amplification by real-time PCR of napA, nirS and ppk showed that nitrogen removal pathway of strain YG-24 was achieved through heterotrophic ammonium ..
  39. Rasigraf O, Schmitt J, Jetten M, Lüke C. Metagenomic potential for and diversity of N-cycle driving microorganisms in the Bothnian Sea sediment. Microbiologyopen. 2017;6: pubmed publisher
    ..The diversity of diagnostic functional genes coding for nitrate reductases (napA;narG), nitrite:nitrate oxidoreductase (nxrA), nitrite reductases (nirK;nirS;nrfA), nitric oxide reductase (nor), ..
  40. Wang H, Ji G, Bai X, He C. Assessing nitrogen transformation processes in a trickling filter under hydraulic loading rate constraints using nitrogen functional gene abundances. Bioresour Technol. 2015;177:217-23 pubmed publisher
    ..Path analysis indicated that amoA/anammox and amoA/(narG+napA) were the two key functional gene groups driving the major processes for NH4(+)-N and NO2(-)-N, respectively...
  41. Begley A, Pollard C. Workforce capacity to address obesity: a Western Australian cross-sectional study identifies the gap between health priority and human resources needed. BMC Public Health. 2016;16:881 pubmed publisher
    ..This study describes the public health nutrition and physical activity (NAPA) practice priorities and explores health managers and practitioner's beliefs regarding workforce capacity to ..
  42. Bian J, Khaychuk V, Angers R, Fernández Borges N, Vidal E, Meyerett Reid C, et al. Prion replication without host adaptation during interspecies transmissions. Proc Natl Acad Sci U S A. 2017;114:1141-1146 pubmed publisher
    ..Here we describe an alternate replicative process, termed nonadaptive prion amplification (NAPA), in which dominant conformers bypass this requirement during particular interspecies transmissions...
  43. Zhang Y, Zhang Y, Feng C, Wu Y, Liu A, Sheng J, et al. Comparative proteomic analysis of human placenta derived from assisted reproductive technology. Proteomics. 2008;8:4344-56 pubmed publisher
    ..The present results reveal that abnormal protein profiles are involved in ART placenta and these differentially expressed proteins may be valuable for the evaluation of potential association between ART treatment and offspring outcome. ..
  44. Han J, Miranda Saavedra D, Luebbering N, Singh A, Sibbet G, Ferguson M, et al. Deep evolutionary conservation of an intramolecular protein kinase activation mechanism. PLoS ONE. 2012;7:e29702 pubmed publisher
    ..These diverse class 2 DYRKs also exhibited conservation of N-terminal NAPA regions located outside of the kinase domain, and were shown to have an essential role in activation loop ..
  45. Bok J, Wiemann P, Garvey G, Lim F, Haas B, Wortman J, et al. Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. BMC Genomics. 2014;15:1011 pubmed publisher global up-regulation of several components of the oxidative stress metabolome including the expression of napA and atfA, the two bZIP transcription factors mediating resistance to reactive oxygen species (ROS) as well as NapA ..
  46. Zheng H, Kim J, Liew M, Yan J, Herrera O, Bok J, et al. Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus. Curr Biol. 2015;25:29-37 pubmed publisher
    ..Phenazine conidiation signaling was conserved in the genetic model A. nidulans and mediated by NapA, a homolog of AP-1-like bZIP transcription factor, which is essential for the response to oxidative stress in ..
  47. Federighi G, Traina G, Bernardi R, Baldi E, Bucherelli C, Scuri R. Contextual fear conditioning modulates the gene expression over time. Arch Ital Biol. 2018;156:40-47 pubmed publisher
    ..Previously, we showed that 2 days after conditioning the expression of the genes Napa, Pnf2, Casp3, Pdrg1, Ywhaz, Stmn1, Bpgm, were positively modulated in CFC rats respect to naïve rats, explor rats ..
  48. Lopez C, Rivera Chávez F, Byndloss M, Bäumler A. The Periplasmic Nitrate Reductase NapABC Supports Luminal Growth of Salmonella enterica Serovar Typhimurium during Colitis. Infect Immun. 2015;83:3470-8 pubmed publisher
    ..Typhimurium. In contrast, a strain lacking a functional periplasmic nitrate reductase (napA mutant) exhibited a marked growth defect in the lumen of the colon. In E...
  49. Mališ M, Došlić N. Nonradiative Relaxation Mechanisms of UV Excited Phenylalanine Residues: A Comparative Computational Study. Molecules. 2017;22: pubmed publisher
    ..The excited state dynamics of theγL(g+)folded form of N-acetylphenylalaninylamide (NAPA B) and its amide-N-methylated derivative (NAPMA B) is reviewed and compared to the dynamics of the monohydrated ..
  50. Chen D, Wang X, Yang K, Wang H. Response of a three dimensional bioelectrochemical denitrification system to the long-term presence of graphene oxide. Bioresour Technol. 2016;214:24-29 pubmed publisher
    ..The abundances of denitrifying genes napA, nirS, and nirK showed no obvious changes with GO concentration lower than 50mgL(-1)...
  51. Jo M, Jung H, Yun S. Retrieving Precise Three-Dimensional Deformation on the 2014 M6.0 South Napa Earthquake by Joint Inversion of Multi-Sensor SAR. Sci Rep. 2017;7:5485 pubmed publisher
    We reconstructed the three-dimensional (3D) surface displacement field of the 24 August 2014 M6.0 South Napa earthquake using SAR data from the Italian Space Agency's COSMO-SkyMed and the European Space Agency's Sentinel-1A satellites...
  52. Lee E, Jung S, Lee S, Lee N, Paik H, Lim S. Lactobacillus plantarum Strain Ln4 Attenuates Diet-Induced Obesity, Insulin Resistance, and Changes in Hepatic mRNA Levels Associated with Glucose and Lipid Metabolism. Nutrients. 2018;10: pubmed publisher
    ..Of the strains tested, Lactobacillus plantarum Ln4 (Ln4), which was obtained from napa cabbage kimchi, significantly reduced lipid accumulation and stimulated glucose uptake in 3T3-L1 adipocytes...
  53. Huang T, Guo L, Zhang H, Su J, Wen G, Zhang K. Nitrogen-removal efficiency of a novel aerobic denitrifying bacterium, Pseudomonas stutzeri strain ZF31, isolated from a drinking-water reservoir. Bioresour Technol. 2015;196:209-16 pubmed publisher
    ..Sequence amplification indicated the presence of the denitrification genes napA, nirS, norB, and nosZ...
  54. Fang W, Yan D, Wang Q, Huang B, Ren Z, Wang X, et al. Changes in the abundance and community composition of different nitrogen cycling groups in response to fumigation with 1,3-dichloropropene. Sci Total Environ. 2019;650:44-55 pubmed publisher
    ..Microorganisms containing nifH, nxrB, napA and qnorB genes were most vulnerable to 1,3-D fumigation...
  55. Soundararajan M, Roos A, Savitsky P, Filippakopoulos P, Kettenbach A, Olsen J, et al. Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition. Structure. 2013;21:986-96 pubmed publisher
    ..member of each DYRK subfamily: DYRK1A with an ATP-mimetic inhibitor and consensus peptide, and DYRK2 including NAPA and DH (DYRK homology) box regions...
  56. Zhang P, Peng Y, Lu J, Li J, Chen H, Xiao L. Microbial communities and functional genes of nitrogen cycling in an electrolysis augmented constructed wetland treating wastewater treatment plant effluent. Chemosphere. 2018;211:25-33 pubmed publisher
    ..Four functional gene pairs of anammox-amoA, (narG + napA)-(nirK + nirS), (narG + napA)-nosZ and qnorB-nosZ showed positive correlations with each other...
  57. Huang T, Zhou S, Zhang H, Bai S, He X, Yang X. Nitrogen Removal Characteristics of a Newly Isolated Indigenous Aerobic Denitrifier from Oligotrophic Drinking Water Reservoir, Zoogloea sp. N299. Int J Mol Sci. 2015;16:10038-60 pubmed publisher
    ..N299. This species exhibits a periplasmic nitrate reductase gene (napA). Its specific growth rate was 0.22 h-1...
  58. Ranabhat S, Ghate R, Bhatta L, Agrawal N, Tankha S. Policy Coherence and Interplay between Climate Change Adaptation Policies and the Forestry Sector in Nepal. Environ Manage. 2018;61:968-980 pubmed publisher
    ..The National Adaptation Programme of Action (NAPA) is more explicit in identifying institutions, organizations, roles and responsibilities, resource allocation (..
  59. Gui M, Chen Q, Ni J. Effect of NaCl on aerobic denitrification by strain Achromobacter sp. GAD-3. Appl Microbiol Biotechnol. 2017;101:5139-5147 pubmed publisher
    ..for N2O reductase) > cnorB (for NO reductase) ? nirS (for cytochrome cd(1) nitrite reductase) > napA (for periplasmic nitrate reductase), accompanied with a time-lapse expression between nosZ and cnorB based on ..
  60. Zhang Y, Ji G. Quantitative responses of potential nitrification and denitrification rates to the size of microbial communities in rice paddy soils. Chemosphere. 2018;211:970-977 pubmed publisher
    ..affiliated with nitrification (amoA and nxrA), denitrification (nirS, nirK and nosZ), nitrate reduction (narG and napA) processes, and measured potential nitrification and denitrification rates (PNRs and PDRs) at 15 sites in Xiamen, ..
  61. Peng X, Zhang R, Duan G, Wang C, Sun N, Zhang L, et al. Production and delivery of Helicobacter pylori NapA in Lactococcus lactis and its protective efficacy and immune modulatory activity. Sci Rep. 2018;8:6435 pubmed publisher
    Helicobacter pylori neutrophil-activating protein A subunit (NapA) has been identified as a virulence factor, a protective antigen and a potent immunomodulator. NapA shows unique application potentials for anti-H...
  62. Miao Y, Zhang X, Jia S, Liao R, Li A. Comprehensive analyses of functional bacteria and genes in a denitrifying EGSB reactor under Cd(II) stress. Appl Microbiol Biotechnol. 2018;102:8551-8560 pubmed publisher
    ..Metagenomic analyses and real-time quantitative PCR consistently indicated that napA encoding nitrate reductase was the predominant denitrifying gene, that could be mainly functioning on the efficient ..
  63. Steel G, Harley C, Boyd A, Morgan A. A screen for dominant negative mutants of SEC18 reveals a role for the AAA protein consensus sequence in ATP hydrolysis. Mol Biol Cell. 2000;11:1345-56 pubmed
    ..Furthermore, this approach of screening for dominant negative mutants in yeast can be applied to other conserved proteins so as to highlight important functional domains in their mammalian counterparts. ..
  64. Stopka S, Rong C, Korte A, Yadavilli S, Nazarian J, Razunguzwa T, et al. Molecular Imaging of Biological Samples on Nanophotonic Laser Desorption Ionization Platforms. Angew Chem Int Ed Engl. 2016;55:4482-6 pubmed publisher
    ..nanophotonic ionization based on laser desorption ionization (LDI) from a highly uniform silicon nanopost array (NAPA)...
  65. He D, Zheng M, Ma T, Li C, Ni J. Interaction of Cr(VI) reduction and denitrification by strain Pseudomonas aeruginosa PCN-2 under aerobic conditions. Bioresour Technol. 2015;185:346-52 pubmed publisher
    ..The capability of strain PCN-2 for Cr(VI) and nitrate reduction was confirmed by PCR analysis of gene ChrR, napA, nirS, cnorB, nosZ, while Cr(VI) reduction was proved via an initial single-electron transfer through Cr(V) ..
  66. Martineau C, Mauffrey F, Villemur R. Comparative Analysis of Denitrifying Activities of Hyphomicrobium nitrativorans, Hyphomicrobium denitrificans, and Hyphomicrobium zavarzinii. Appl Environ Microbiol. 2015;81:5003-14 pubmed publisher
    ..Significant increases in the relative gene expression levels of the nitrate (napA) and nitrite (nirK) reductase genes were also noted for H. nitrativorans at higher nitrate and NaCl concentrations...
  67. Lee C, Yashiro S, Dotson D, Uzdavinys P, Iwata S, Sansom M, et al. Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights. J Gen Physiol. 2014;144:529-44 pubmed publisher
    ..An equivalent salt bridge is present in the homologous transporter NapA, but not in the only other known crystal structure of NhaA, which provides the foundation of most existing ..
  68. Yang L, Ren Y, Liang X, Zhao S, Wang J, Xia Z. Nitrogen removal characteristics of a heterotrophic nitrifier Acinetobacter junii YB and its potential application for the treatment of high-strength nitrogenous wastewater. Bioresour Technol. 2015;193:227-33 pubmed publisher
    ..The successful PCR amplification of hao, napA and nirS genes further provided additional evidence of heterotrophic nitrification and aerobic denitrification by ..
  69. Tran L, Mattsson J, Nodin B, Jönsson P, Planck M, Jirström K, et al. Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma. Appl Immunohistochem Mol Morphol. 2016;24:648-659 pubmed
    ..5 (CK5), p63, and p40 are commonly used immunohistochemical markers for squamous cell carcinoma, and napsin A (NAPA) and thyroid transcription factor 1 (TTF-1) are markers for adenocarcinoma of the lung...
  70. Balla A, Cho K, Kim Y, Maeng H. Simultaneous Determination of Procainamide and N-acetylprocainamide in Rat Plasma by Ultra-High-Pressure Liquid Chromatography Coupled with a Diode Array Detector and Its Application to a Pharmacokinetic Study in Rats. Pharmaceutics. 2018;10: pubmed publisher
    ..for the simultaneous determination of Procainamide (PA) and its major metabolite, N-acetylprocainamide (NAPA), in rat plasma was developed and validated...
  71. Sennato S, Carlini L, Truzzolillo D, Bordi F. Salt-induced reentrant stability of polyion-decorated particles with tunable surface charge density. Colloids Surf B Biointerfaces. 2016;137:109-20 pubmed publisher
    The electrostatic complexation between DOTAP/DOPC unilamellar liposomes and an oppositely charged polyelectrolyte (NaPA) has been investigated in a wide range of the liposome surface charge density...
  72. Attfield K, Dobson C, Henn J, Acosta M, Smorodinsky S, Wilken J, et al. Injuries and Traumatic Psychological Exposures Associated with the South Napa Earthquake - California, 2014. MMWR Morb Mortal Wkly Rep. 2015;64:975-8 pubmed publisher
    On August 24, 2014, at 3:20 a.m., a magnitude 6.0 earthquake struck California, with its epicenter in Napa County (1)...
  73. Gholami F, Nikookheslat S, Salekzamani Y, Boule N, Jafari A. Effect of aerobic training on nerve conduction in men with type 2 diabetes and peripheral neuropathy: A randomized controlled trial. Neurophysiol Clin. 2018;48:195-202 pubmed publisher
    ..007). Changes in peroneal and tibial motor NCV and nerve action potential amplitude (NAPA) in all nerves studied were not different between groups (P>0.05)...
  74. Kim N, Jang S, Kim S, Lee H, Kim Y, Ryu J, et al. Use of phytic acid and hyper-salting to eliminate Escherichia coli O157:H7 from napa cabbage for kimchi production in a commercial plant. Int J Food Microbiol. 2015;214:24-30 pubmed publisher
    ..a new salting method using natural phytic acid (PA) to ensure the microbiological safety and quality of salted napa cabbage used for kimchi production...
  75. Balusu R, Rhodes E, Liburd O, Fadamiro H. Management of Yellowmargined Leaf Beetle Microtheca ochroloma (Coleoptera: Chrysomelidae) Using Turnip as a Trap Crop. J Econ Entomol. 2015;108:2691-701 pubmed publisher
    ..During the first season of our on-farm trial, with napa cabbage and mustard as the cash crops, using turnip as a trap crop effectively reduced both beetle numbers and cash ..
  76. Cai H, Ye F, Michel A, Murphy G, Sasazuki S, Taylor P, et al. Helicobacter pylori blood biomarker for gastric cancer risk in East Asia. Int J Epidemiol. 2016;45:774-81 pubmed publisher
    ..Sero-positivity to 10 H. pylori antigens (Omp, CagA, VacA, HcpC, HP 0305, GroEL, NapA, HyuA, Cad, HpaA) was associated with a 1.29- to 3.26-fold increase in odds of gastric cancer...
  77. Cieniewicz E, Pethybridge S, Gorny A, Madden L, McLane H, Perry K, et al. Spatiotemporal spread of grapevine red blotch-associated virus in a California vineyard. Virus Res. 2017;241:156-162 pubmed publisher
    ..A 2-hectare Vitis vinifera cv. 'Cabernet franc' vineyard in Napa County, California, USA was selected for monitoring GRBaV spread over a three-year period (2014-2016) based on an ..
  78. Inoue H, Matsuzaki Y, Tanaka A, Hosoi K, Ichimura K, Arasaki K, et al. γ-SNAP stimulates disassembly of endosomal SNARE complexes and regulates endocytic trafficking pathways. J Cell Sci. 2015;128:2781-94 pubmed publisher
    ..N-ethylmaleimide-sensitive factor (NSF) and its attachment protein, α-SNAP (encoded by NAPA), catalyze disassembly of the SNARE complexes in the secretory and endocytic pathways to recycle them for the next ..
  79. Cao H, Shao Z, Li J, Zhang W, Qian P. Phylogenetic diversity of nitrogen-utilizing genes in hydrothermal chimneys from 3 middle ocean ridges. Extremophiles. 2015;19:1173-82 pubmed publisher
    Nitrogen-metabolizing genes, including nitrogenase (nifH), periplasmic nitrate reductase (napA), and cytochrome cd 1-type nitrite reductase (nirS), were collected from hydrothermal chimney sulfides on 3 middle ocean ridges and compared ..
  80. Shin S, Shutoh N, Tonai M, Ogata N. The Effect of Capsaicin-Containing Food on the Swallowing Response. Dysphagia. 2016;31:146-53 pubmed publisher
    ..Pickled Napa cabbage was selected as the food for the present study. One portion (10 g) of pickled Napa cabbage provides 1...
  81. Gupta K, Donlan J, Hopper J, Uzdavinys P, Landreh M, Struwe W, et al. The role of interfacial lipids in stabilizing membrane protein oligomers. Nature. 2017;541:421-424 pubmed publisher
    ..the lowest oligomeric strength, but not for the substantially more stable homologous Thermus thermophilus protein NapA. We found that lipid binding is obligatory for dimerization of NhaA, whereas NapA has adapted to form an interface ..
  82. Wang H, Ji G, Bai X. Distribution patterns of nitrogen micro-cycle functional genes and their quantitative coupling relationships with nitrogen transformation rates in a biotrickling filter. Bioresour Technol. 2016;209:100-7 pubmed publisher
    ..Combined analyses revealed the anammox, nas, napA, narG, nirS, and nxrA genes were the dominant enriched genes in different treatment layers...
  83. Zheng M, Li C, Liu S, Gui M, Ni J. Potential application of aerobic denitrifying bacterium Pseudomonas aeruginosa PCN-2 in nitrogen oxides (NOx) removal from flue gas. J Hazard Mater. 2016;318:571-578 pubmed publisher
    ..revealed that high efficient NO removal was attributed to the coordinate regulation of gene expressions including napA (for periplasmic nitrate reductase), nirS (for cytochrome cd1 nitrite reductase) and cnorB (for NO reductase)...
  84. Veronesi F, Giavaresi G, Maglio M, Scotto D Abusco A, Politi L, Scandurra R, et al. Chondroprotective activity of N-acetyl phenylalanine glucosamine derivative on knee joint structure and inflammation in a murine model of osteoarthritis. Osteoarthritis Cartilage. 2017;25:589-599 pubmed publisher
    ..The ability of N-acetyl phenylalanine derivative (NAPA) to increase cartilage matrix components and to reduce inflammatory cytokines, inhibiting IKKα kinase activity, ..
  85. Miao Y, Bhushan J, Dani A, Vig M. Na+ influx via Orai1 inhibits intracellular ATP-induced mTORC2 signaling to disrupt CD4 T cell gene expression and differentiation. elife. 2017;6: pubmed publisher
    ..Here we show that α-SNAP hypomorph, hydrocephalus with hopping gait, Napahyh/hyh mice harbor significant defects in CD4 T cell gene expression and Foxp3 regulatory T cell (..
  86. Pan J, Qi S, Sun Y, Jiang Y, Zhao N, Huang L, et al. Nitrogen removal and nitrogen functional gene abundances in three subsurface wastewater infiltration systems under different modes of aeration and influent C/N ratios. Bioresour Technol. 2017;241:1162-1167 pubmed publisher
    ..and TN removal and the enrichment of nitrogen removal functional genes (amoA, nxrA, narG, napA, nirK, nirS, qnorB and nosZ) compared to NA SWIS, especially under high influent C/N ratio...
  87. Uzdavinys P, Coinçon M, Nji E, Ndi M, Winkelmann I, von Ballmoos C, et al. Dissecting the proton transport pathway in electrogenic Na+/H+ antiporters. Proc Natl Acad Sci U S A. 2017;114:E1101-E1110 pubmed publisher we show that we can switch the antiport activity of the bacterial Na+/H+ antiporter NapA from being electrogenic to electroneutral by the mutation of a single lysine residue (K305)...
  88. Gui M, Chen Q, Ni J. Effect of sulfamethoxazole on aerobic denitrification by strain Pseudomonas stutzeri PCN-1. Bioresour Technol. 2017;235:325-331 pubmed publisher
    ..Furthermore, corresponding inhibition of SMX on denitrifying genes expression (nosZ>nirS>cnorB>napA) was found with a time-lapse expression between nosZ and cnorB...
  89. Sun Y, Pan J, Qi S, Fei H. Effects of hydraulic loading rate and aeration mode on nitrogen removal and nitrogen functional gene abundances in subsurface wastewater infiltration systems. Water Sci Technol. 2017;76:210-218 pubmed publisher
    ..and total nitrogen (TN) removal and the enrichment of nitrogen removal functional genes (amoA, nxrA, napA, narG, nirK and qnorB) compared to the non-aerated SWIS, especially for high HLRs. IA SWIS (79.7%-85...
  90. Wang X, Shu D, Yue H. Taxonomical and functional microbial community dynamics in an Anammox-ASBR system under different Fe (III) supplementation. Appl Microbiol Biotechnol. 2016;100:10147-10163 pubmed
    ..78 ± 0.29, and 83.66 ± 0.46 %, respectively. Pearson's correlation coefficients between anammox-(narG + napA), anammox-nrfA, and anammox-FeRB all exceeded r = 0.820 (p < 0...
  91. Landreh M, Marklund E, Uzdavinys P, Degiacomi M, Coincon M, Gault J, et al. Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters. Nat Commun. 2017;8:13993 pubmed publisher study the conformational stability and lipid-binding properties of the Na+/H+ exchanger NapA from Thermus thermophilus and compare this to the prototypical antiporter NhaA from Escherichia coli and the human ..
  92. Huang F, Pan L, Lv N, Tang X. Characterization of novel Bacillus strain N31 from mariculture water capable of halophilic heterotrophic nitrification-aerobic denitrification. J Biosci Bioeng. 2017;124:564-571 pubmed publisher
    ..The existence of hao, napA and nirS genes further proved the heterotrophic nitrification-aerobic denitrification capability of N31...