MYL5

Summary

Gene Symbol: MYL5
Description: myosin, light chain 5, regulatory
Alias: MYLC2, myLC-2, myosin light chain 5, myosin regulatory light chain 5, myosin, light polypeptide 5, regulatory, superfast myosin regulatory light chain 2
Species: human

Top Publications

  1. pmc Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells
    Yu Zhong
    Department of Neurosurgery, Molecular Neuroscience and Vascular Biology Laboratory, University of Kentucky Medical Center, Lexington, Kentucky 40536, USA
    J Cereb Blood Flow Metab 30:522-33. 2010
  2. ncbi The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates
    C Collins
    Department of Medical Genetics, University of British Columbia, Vancouver, Canada
    Hum Mol Genet 1:727-33. 1992
  3. ncbi Isolation and structure of cat superfast myosin light chain-2 cDNA and evidence for the identity of its human homologue
    H Qin
    Department of Physiology, University of Sydney, NSW, Australia
    Biochem Biophys Res Commun 200:1277-82. 1994
  4. ncbi Myosins: a diverse superfamily
    J R Sellers
    National Heart, Lung and Blood Institute, National Institutes of Health, Building 10, Room 8N202, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1496:3-22. 2000

Scientific Experts

  • J R Sellers
  • Yu Zhong
  • Bernhard Hennig
  • Michal Toborek
  • H Qin
  • J F Hoh
  • C Collins
  • B J Morris
  • M R Hayden
  • K Schappert

Detail Information

Publications4

  1. pmc Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells
    Yu Zhong
    Department of Neurosurgery, Molecular Neuroscience and Vascular Biology Laboratory, University of Kentucky Medical Center, Lexington, Kentucky 40536, USA
    J Cereb Blood Flow Metab 30:522-33. 2010
    ..The present data indicate the critical function of intact lipid rafts and the Rho signaling in HIV-1-mediated upregulation of P-gp and potential development of drug resistance in brain endothelial cells...
  2. ncbi The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates
    C Collins
    Department of Medical Genetics, University of British Columbia, Vancouver, Canada
    Hum Mol Genet 1:727-33. 1992
    ..We report here the identification and characterization of a gene (MYL5) that encodes a novel regulatory myosin light chain isoprotein and maps 700 kb from the human chromosome 4p ..
  3. ncbi Isolation and structure of cat superfast myosin light chain-2 cDNA and evidence for the identity of its human homologue
    H Qin
    Department of Physiology, University of Sydney, NSW, Australia
    Biochem Biophys Res Commun 200:1277-82. 1994
    A full-length cDNA clone coding for superfast myosin light chain-2 (MyLC2) was isolated from an expression cDNA library prepared from cat masseter muscle and was fully characterized...
  4. ncbi Myosins: a diverse superfamily
    J R Sellers
    National Heart, Lung and Blood Institute, National Institutes of Health, Building 10, Room 8N202, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1496:3-22. 2000
    ..This review will focus on myosins from class IV, VI, VII, VIII, X, XI, XII, XIII, XIV and XV. In addition, the function of myosin II in non-muscle cells will also be discussed...