Gene Symbol: MS4A5
Description: membrane spanning 4-domains A5
Alias: CD20-L2, CD20L2, TETM4, membrane-spanning 4-domains subfamily A member 5, CD20 antigen-like 2, testis-expressed transmembrane protein 4, testis-expressed transmembrane-4 protein
Hulett M, Pagler E, Hornby J, Hogarth P, Eyre H, Baker E, et al
. Isolation, tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-beta. Biochem Biophys Res Commun. 2001;280:374-9 pubmed
..Herein, we report the identification and characterization of a human gene, TETM4, that encodes a novel four-transmembrane protein related to CD20 and FcepsilonRIbeta...
Ishibashi K, Suzuki M, Sasaki S, Imai M. Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor. Gene. 2001;264:87-93 pubmed
..The identification of this relatively large gene family in various tissues will allow the further elucidation of physiological significance of this gene family, that is currently unclear. ..
Liang Y, Tedder T. Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. Genomics. 2001;72:119-27 pubmed
..1 along with CD20, FcepsilonRIbeta, and HTm4. Thus, like CD20 and FcepsilonRIbeta, the other MS4A family members are likely to be components of oligomeric cell surface complexes that serve diverse signal transduction functions. ..
Liang Y, Buckley T, Tu L, Langdon S, Tedder T. Structural organization of the human MS4A gene cluster on Chromosome 11q12. Immunogenetics. 2001;53:357-68 pubmed
..Sequence polymorphisms were identified in the MS4A6E gene and common splice variants were observed for the MS4A4A, MS4A5, MS4A6A, and MS4A7 genes. Thus, the MS4A family currently includes 24 distinct human and mouse genes...