MID1IP1

Summary

Gene Symbol: MID1IP1
Description: MID1 interacting protein 1
Alias: G12-like, MIG12, S14R, STRAIT11499, THRSPL, MID1 interacting G12-like protein, MID1 interacting protein 1 (gastrulation specific G12-like), gastrulation specific G12 homolog, gastrulation-specific G12-like protein, mid1-interacting G12-like protein, mid1-interacting protein 1, spot 14-R, spot 14-related protein
Species: human

Top Publications

  1. ncbi Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway
    Abhik Shah
    Bioinformatics Program, University of Michigan, Ann Arbor, MI 48109, USA
    BMC Bioinformatics 10:433. 2009
  2. ncbi Discovery and characterization of nutritionally regulated genes associated with muscle growth in Atlantic salmon
    Neil I Bower
    Scottish Oceans Institute, School of Biology, University of St Andrews, St Andrews, Fife, United Kingdom
    Physiol Genomics 42:114-30. 2010
  3. ncbi Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules
    Caterina Berti
    Telethon Institute of Genetics and Medicine, 80131 Naples, Italy
    BMC Cell Biol 5:9. 2004
  4. ncbi Crystal structure of Spot 14, a modulator of fatty acid synthesis
    Christopher L Colbert
    Department of Biochemistry and Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9050, USA
    Proc Natl Acad Sci U S A 107:18820-5. 2010
  5. ncbi MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization
    Makoto Suzuki
    Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Nishigonaka 38, Myodaiji, Okazaki 444 8585, Aichi, Japan
    Development 137:2329-39. 2010
  6. ncbi Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis
    Chai Wan Kim
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9046, USA
    Proc Natl Acad Sci U S A 107:9626-31. 2010
  7. ncbi Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis
    Derrick L Aipoalani
    Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, Minnesota 55455, USA
    Endocrinology 151:2071-7. 2010
  8. ncbi Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X
    W M Casey
    GlaxoSmithKline, US Research and Development, Safety Assessment, NC 27709, USA
    Biomarkers 13:364-76. 2008
  9. ncbi Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development
    Julie M Hayes
    Department of Molecular Cell and Developmental Biology, and Institute for Cellular and Molecular Biology, University Station C1000, University of Texas, Austin, TX 78712, USA
    Dev Biol 312:115-30. 2007
  10. ncbi Identification of MIG12 as a mediator for stimulation of lipogenesis by LXR activation
    Jun Inoue
    Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113 8657, Japan
    Mol Endocrinol 25:995-1005. 2011

Scientific Experts

  • Caterina Berti
  • Neil I Bower
  • Abhik Shah
  • Chai Wan Kim
  • Jun Inoue
  • Christopher L Colbert
  • Young Ah Moon
  • Jay D Horton
  • Makoto Suzuki
  • Hyock Joo Kwon
  • Derrick L Aipoalani
  • Naoto Ueno
  • W M Casey
  • Julie M Hayes
  • Makoto Shimizu
  • Emina Ikeuchi
  • Shin ichi Satoh
  • Ryuichiro Sato
  • Tomoko Nishimaki-Mogami
  • Kohei Yamasaki
  • Yoko Fujiwara
  • Brennon L O'Callaghan
  • Lisa Henry
  • Johann Deisenhofer
  • Dong Cheng
  • Yusuke Hara
  • Maya Palnitkar
  • Cary N Mariash
  • Howard C Towle
  • Douglas G Mashek
  • Kevin Fitzgerald
  • Sahng Wook Park
  • Takamasa S Yamamoto
  • Chiyo Takagi
  • William B McKean
  • N F Cariello
  • L Yoon
  • H L Jordan
  • H Ni
  • T Brodie
  • Atsushi Kitayama
  • Tae Joo Park
  • Su Kyoung Kim
  • Philip B Abitua
  • Emily R Herrington
  • John B Wallingford
  • Matthew W Grow

Detail Information

Publications10

  1. ncbi Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway
    Abhik Shah
    Bioinformatics Program, University of Michigan, Ann Arbor, MI 48109, USA
    BMC Bioinformatics 10:433. 2009
    ..The topology of a biological pathway provides clues as to how a pathway operates, but rationally using this topology information with observed gene expression data remains a challenge...
  2. ncbi Discovery and characterization of nutritionally regulated genes associated with muscle growth in Atlantic salmon
    Neil I Bower
    Scottish Oceans Institute, School of Biology, University of St Andrews, St Andrews, Fife, United Kingdom
    Physiol Genomics 42:114-30. 2010
    ..expression during the proliferative phase of the culture (FOXD1, DRG1) or as cells differentiated (SMYD1, RTN1, MID1IP1, HSP90A, novel transcript GE617747)...
  3. ncbi Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules
    Caterina Berti
    Telethon Institute of Genetics and Medicine, 80131 Naples, Italy
    BMC Cell Biol 5:9. 2004
    ..Mid1 acts as an E3 ubiquitin ligase, regulating PP2A degradation on microtubules...
  4. ncbi Crystal structure of Spot 14, a modulator of fatty acid synthesis
    Christopher L Colbert
    Department of Biochemistry and Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9050, USA
    Proc Natl Acad Sci U S A 107:18820-5. 2010
    ..65 Å and biochemical data showing that S14 can form heterodimers with MIG12. MIG12 modulates fatty acid synthesis by inducing the polymerization and activity of acetyl-CoA carboxylase, the ..
  5. ncbi MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization
    Makoto Suzuki
    Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Nishigonaka 38, Myodaiji, Okazaki 444 8585, Aichi, Japan
    Development 137:2329-39. 2010
    ..We also found that the xMIDs and their interacting protein Mig12 were coordinately required for microtubule stabilization during remodeling of the neural plate...
  6. ncbi Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis
    Chai Wan Kim
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9046, USA
    Proc Natl Acad Sci U S A 107:9626-31. 2010
    ..Here, we show that MIG12, a 22 kDa cytosolic protein of previously unknown function, binds to ACC and lowers the threshold for citrate ..
  7. ncbi Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis
    Derrick L Aipoalani
    Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, Minnesota 55455, USA
    Endocrinology 151:2071-7. 2010
    ..was postulated that this difference could be due to the expression of a paralogous gene called S14R (S14 related; Mig12) in the liver but not mammary tissue...
  8. ncbi Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X
    W M Casey
    GlaxoSmithKline, US Research and Development, Safety Assessment, NC 27709, USA
    Biomarkers 13:364-76. 2008
    ..transducer and activator of transcription 3), Socs3 (suppressor of cytokine signalling 3) and Mid1ip1 (Mid1 interacting protein 1)...
  9. ncbi Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development
    Julie M Hayes
    Department of Molecular Cell and Developmental Biology, and Institute for Cellular and Molecular Biology, University Station C1000, University of Texas, Austin, TX 78712, USA
    Dev Biol 312:115-30. 2007
    ..b>Mig12-GFP localizes very strongly to the base of cilia and confocal imaging of this construct allows for simple ..
  10. ncbi Identification of MIG12 as a mediator for stimulation of lipogenesis by LXR activation
    Jun Inoue
    Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113 8657, Japan
    Mol Endocrinol 25:995-1005. 2011
    ..We describe a novel LXR target, midline-1-interacting G12-like protein (MIG12), which has been recently identified as an acetyl-coenzyme A carboxylase-binding protein...