Gene Symbol: membralin
Description: transmembrane protein 259
Alias: ASBABP1, C19orf6, MBRL, MEMBRALIN, R32184_3, membralin, aspecific BCL2 ARE-binding protein 1
Li W, Nimaichand S, Jiang Z, Liu M, Khieu T, Kim C, et al
. Streptomyces canchipurensis sp. nov., isolated from a limestone habitat. Antonie Van Leeuwenhoek. 2014;106:1119-26 pubmed publisher
..Using polyphasic taxonomy, a Streptomyces strain, MBRL 172(T), has been characterized...
Yang B, Qu M, Wang R, Chatterton J, Liu X, Zhu B, et al
. The critical role of membralin in postnatal motor neuron survival and disease. elife. 2015;4: pubmed publisher
Hitherto, membralin has been a protein of unknown function. Here, we show that membralin mutant mice manifest a severe and early-onset motor neuron disease in an autosomal recessive manner, dying by postnatal day 5-6...
Thawai C, Kittiwongwattana C, Thanaboripat D, Laosinwattana C, Koohakan P, Parinthawong N. Micromonospora soli sp. nov., isolated from rice rhizosphere soil. Antonie Van Leeuwenhoek. 2016;109:449-56 pubmed publisher
..1 % 16S rRNA gene sequence similarity) and Micromonospora kangleipakensis MBRL 34(T) (98.8 %). DNA-DNA relatedness between strain SL3-70(T) and its relatives ranged from 21.2 % Â± 0.6 to 38...
Ma J, Zhang L, Wang G, Zhang S, Zhang X, WANG Y, et al
. Rhodococcus gannanensis sp. nov., a novel endophytic actinobacterium isolated from root of sunflower (Helianthus annuus L.). Antonie Van Leeuwenhoek. 2017;110:1113-1120 pubmed publisher
..showed that strain M1T belongs to the genus Rhodococcus and clustered with Rhodococcus canchipurensis MBRL 353T (99.1%, sequence similarity) and Rhodococcus pedocola UC12T (98.7%)...
Chen Y, Davidson B, Cheng C, Maitra A, Giuntoli R, Hruban R, et al
. Identification and characterization of membralin, a novel tumor-associated gene, in ovarian carcinoma. Biochim Biophys Acta. 2005;1730:96-102 pubmed
..A novel gene, membralin (GeneBank accession number: DQ005958), was cloned from a human ovarian cancer cell line...
Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, et al
. ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating ?-secretase activity. Nat Commun. 2017;8:1472 pubmed publisher
..Here, using proteomic and FRET analyses, we demonstrate that the ER protein membralin is an ERAD component, which mediates degradation of ER luminal and membrane substrates...
Andersson O, von Euler G. Characterization and expression of the gene encoding membralin, an evolutionary conserved protein expressed in the central nervous system. Brain Res Gene Expr Patterns. 2002;1:205-12 pubmed
We have identified a novel gene that encodes an evolutionary conserved protein that we name membralin since it contains multiple transmembrane regions. The human gene C19orf6 localizes to chromosome 19p13.3...