MEGF8

Summary

Gene Symbol: MEGF8
Description: multiple EGF-like-domains 8
Alias: C19orf49, CRPT2, EGFL4, SBP1, EGF-like domain-containing protein 4, EGF-like-domain, multiple 4, HBV pre-s2 binding protein 1, epidermal growth factor-like protein 4, multiple epidermal growth factor-like domains protein 8
Species: human

Top Publications

  1. ncbi Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Pathol 202:321-9. 2004
  2. ncbi Genetic determinants of systolic and pulse pressure in an intercross between normotensive inbred rats
    Bastien Llamas
    Experimental Cardiovascular Biology Research Unit, Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Canada H2W 1R7
    Hypertension 48:921-6. 2006
  3. doi Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1α to promote hepatocellular carcinoma invasiveness
    Cheng Huang
    Liver Cancer Institute, Fudan University, Shanghai, China
    Clin Cancer Res 18:3042-53. 2012
  4. pmc Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element
    Andrew P Norgan
    Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Biol Chem 288:26147-56. 2013
  5. ncbi Strength of relationships of the pulse wave velocity and central hemodynamic indices with the serum N-terminal fragment B-type natriuretic peptide levels in men: a worksite cohort study
    Mari Odaira
    Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
    Circ J 76:1928-33. 2012
  6. pmc Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization
    Stephen R F Twigg
    Clinical Genetics Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK
    Am J Hum Genet 91:897-905. 2012
  7. pmc Global analysis of yeast mRNPs
    Sarah F Mitchell
    Department of Chemistry and Biochemistry, University of Colorado Boulder, Boulder, Colorado, USA
    Nat Struct Mol Biol 20:127-33. 2013
  8. doi Selenium-binding protein 1 may decrease gastric cellular proliferation and migration
    Chenjing Zhang
    Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, PR China
    Int J Oncol 42:1620-9. 2013
  9. doi 2D-DIGE to identify proteins associated with gestational diabetes in omental adipose tissue
    Karen Oliva
    Mercy Perinatal Research Centre, Mercy Hospital for Women, Heidelberg, Victoria, Australia
    J Endocrinol 218:165-78. 2013
  10. pmc Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins
    Purusharth Rajyaguru
    Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA
    Mol Cell 45:244-54. 2012

Scientific Experts

  • B Cooke
  • Jill C Preston
  • Tianhong Li
  • Tara Smith
  • J Krushkal
  • K Kohara
  • C S Giometti
  • Jin Zhang
  • Wancai Yang
  • Wenfeng Fang
  • Nicole M Pohl
  • Veronique Hugouvieux
  • Christelle Dutilleul
  • Guoan Chen
  • Andrew P Norgan
  • Sarah F Mitchell
  • Chenjing Zhang
  • Karen Oliva
  • Roy Parker
  • Meipei She
  • Anita Jerome-Morais
  • Mari Odaira
  • Purusharth Rajyaguru
  • Stephen R F Twigg
  • Cheng Huang
  • Camilla Lööv
  • Alan M Diamond
  • Shulin Ju
  • Wei Guo Dong
  • Amy L Silvers
  • Rukhsana Sultana
  • Xiuli Bi
  • David J Katzmann
  • Chang Tong
  • Zhen Zhang
  • Silvia Haase
  • Jacques Bourguignon
  • Agnès Jourdain
  • Christopher B Lee
  • W Douglas Fairlie
  • David G Beer
  • Thomas J Giordano
  • Dafydd G Thomas
  • Mark B Orringer
  • Ishara Azmi
  • Bastien Llamas
  • Zhihua Hua
  • Hideaki Fujita
  • Yin Ying Lu
  • Shengrong Shen
  • Wen Xu
  • Nana Wang
  • Gregory M Lynch
  • Wensheng Pan
  • Andreas S Schroeder
  • Saumya Jain
  • Undurti N Das
  • Mark J Bailey
  • Xiaoyuan Fan
  • Gillian Barker
  • Xiang Xu
  • Martha Lappas
  • Gregory E Rice
  • Ishara F Azmi
  • Guogang Li
  • Zhaohui Xu
  • Johanna A Payne
  • Brian A Davies
  • Rui Liu
  • Matthew I Jackson
  • Chengyu Gu
  • Samantha J L Knight
  • Yifeng He
  • Judith A Goodship
  • Ming Kuang
  • Tadashi Kondo
  • Masanobu Yoshida
  • Simon J McGowan
  • Guangyu Ding
  • Irina Hüning
  • Ted Ebendal
  • Nursel E Elçioglu
  • Andrew O M Wilkie
  • Anna Erlandsson
  • Hirofumi Tomiyama
  • Dagan Jenkins
  • Gabriele Gillessen-Kaesbach
  • Mikio Nagata
  • Gerald F Combs
  • Opher Gileadi

Detail Information

Publications41

  1. ncbi Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Pathol 202:321-9. 2004
    ..The protein expression status of human selenium-binding protein 1 (SBP1) in human tumours and the exact function of this protein are not known...
  2. ncbi Genetic determinants of systolic and pulse pressure in an intercross between normotensive inbred rats
    Bastien Llamas
    Experimental Cardiovascular Biology Research Unit, Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Canada H2W 1R7
    Hypertension 48:921-6. 2006
    ..Only suggestive quantitative trait loci were found for systolic blood pressure, but the strongest one (Sbp1) had the same peak and linkage probability profile as Pp1...
  3. doi Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1α to promote hepatocellular carcinoma invasiveness
    Cheng Huang
    Liver Cancer Institute, Fudan University, Shanghai, China
    Clin Cancer Res 18:3042-53. 2012
    We aimed to characterize the role of selenium-binding protein 1 (SBP1) in hepatocellular carcinoma (HCC) invasiveness and underlying clinical significance.
  4. pmc Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element
    Andrew P Norgan
    Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Biol Chem 288:26147-56. 2013
    ..The Vta1 carboxyl-terminal Vta1 SBP1 Lip5 (VSL) domain stimulates Vps4 function by facilitating oligomerization of Vps4 into its active state...
  5. ncbi Strength of relationships of the pulse wave velocity and central hemodynamic indices with the serum N-terminal fragment B-type natriuretic peptide levels in men: a worksite cohort study
    Mari Odaira
    Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
    Circ J 76:1928-33. 2012
    ..The present cross-sectional study was conducted to examine the strength of the relationships of the arterial stiffness and central hemodynamic indices with the serum N-terminal fragment B-type natriuretic peptide (NT-pro BNP) levels...
  6. pmc Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization
    Stephen R F Twigg
    Clinical Genetics Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK
    Am J Hum Genet 91:897-905. 2012
    ..Here, we describe a disorder caused by mutations in multiple epidermal-growth-factor-like-domains 8 (MEGF8), which exhibits substantial clinical overlap with Carpenter syndrome but is frequently associated with abnormal ..
  7. pmc Global analysis of yeast mRNPs
    Sarah F Mitchell
    Department of Chemistry and Biochemistry, University of Colorado Boulder, Boulder, Colorado, USA
    Nat Struct Mol Biol 20:127-33. 2013
    ..Cross-linking and immunoprecipitation (CLIP) analyses of the P-body components Pat1, Lsm1, Dhh1 and Sbp1 identified sites of interaction on specific mRNAs, revealing positional binding preferences and co-assembly ..
  8. doi Selenium-binding protein 1 may decrease gastric cellular proliferation and migration
    Chenjing Zhang
    Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, PR China
    Int J Oncol 42:1620-9. 2013
    It has been reported that suppression of selenium‑binding protein 1 (SBP1) occurs in many human malignancies which is considered to play an important role in cancer development and progression...
  9. doi 2D-DIGE to identify proteins associated with gestational diabetes in omental adipose tissue
    Karen Oliva
    Mercy Perinatal Research Centre, Mercy Hospital for Women, Heidelberg, Victoria, Australia
    J Endocrinol 218:165-78. 2013
    ..dehydrogenase B chain (LDHB), perilipin-1 (PLIN1), peroxiredoxin-6 (PRX6 (PRDX6)), selenium-binding protein 1 (SBP1) and vinculin (VINC (VCL))...
  10. pmc Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins
    Purusharth Rajyaguru
    Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA
    Mol Cell 45:244-54. 2012
    ..RGG domain-containing proteins in yeast copurify with eIF4E/G and we demonstrate that two such proteins, Npl3 and Sbp1, also directly bind eIF4G and repress translation in a manner dependent on their RGG motifs...
  11. pmc Engulfing astrocytes protect neurons from contact-induced apoptosis following injury
    Camilla Lööv
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    PLoS ONE 7:e33090. 2012
    ..qRT-PCR analysis showed that members of both ced pathways and Megf8 are expressed in the cell culture, indicating their possible involvement in astrocytic engulfment...
  12. pmc Inverse association between glutathione peroxidase activity and both selenium-binding protein 1 levels and Gleason score in human prostate tissue
    Anita Jerome-Morais
    Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA
    Prostate 72:1006-12. 2012
    ..Se-containing proteins including members of the glutathione peroxidase (GPx) family and Selenium-Binding Protein 1 (SBP1) have been linked to either cancer risk or development...
  13. pmc Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts
    Nicole M Pohl
    Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA
    PLoS ONE 4:e7774. 2009
    It has been shown that selenium-binding protein 1 (SBP1) is significantly downregulated in different human cancers. Its regulation and function have not yet been established.
  14. pmc Arabidopsis putative selenium-binding protein1 expression is tightly linked to cellular sulfur demand and can reduce sensitivity to stresses requiring glutathione for tolerance
    Veronique Hugouvieux
    Laboratoire de Physiologie Cellulaire Végétale, UMR 5168, Commissariat à l Energie Atomique CNRS Université Joseph Fourier INRA, Institut de Recherches en Technologies et Sciences pour le Vivant, Commissariat a l Energie Atomique Grenoble, 38054 Grenoble Cedex 9, France
    Plant Physiol 151:768-81. 2009
    Selenium-Binding Protein1 (SBP1) gene expression was studied in Arabidopsis (Arabidopsis thaliana) seedlings challenged with several stresses, including cadmium (Cd), selenium {selenate [Se(VI)] and selenite [Se(IV)]}, copper (Cu), zinc (..
  15. doi SQUAMOSA-PROMOTER BINDING PROTEIN 1 initiates flowering in Antirrhinum majus through the activation of meristem identity genes
    Jill C Preston
    Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045, USA
    Plant J 62:704-12. 2010
    ..In the distantly related core eudicot species Antirrhinum majus L., paralogous SBP-box proteins SBP1 and SBP2 have likewise been implicated in regulating the AP1 ortholog SQUAMOSA (SQUA)...
  16. pmc Decreased selenium-binding protein 1 in esophageal adenocarcinoma results from posttranscriptional and epigenetic regulation and affects chemosensitivity
    Amy L Silvers
    Section of Thoracic Surgery, Department of Surgery and Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Clin Cancer Res 16:2009-21. 2010
    ..Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal ..
  17. doi Reduced selenium-binding protein 1 is associated with poor survival rate in gastric carcinoma
    Jin Zhang
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China
    Med Oncol 28:481-7. 2011
    Human selenium-binding protein 1 (SBP1) is known to play a key role in the development and progression of many cancers. The role of SBP1 expression in gastric carcinoma (GC) is far from being fully established...
  18. doi Altered expression of selenium-binding protein 1 in gastric carcinoma and precursor lesions
    Jin Zhang
    Department of Gastroenterology, Renmin Hospital of Wuhan University, 9 Ziyang Road, 430060, Wuhan, Hubei Province, China
    Med Oncol 28:951-7. 2011
    Selenium-binding protein 1 (SBP1) has been shown to be greatly reduced in various human cancers...
  19. pmc Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein
    Wenfeng Fang
    Department of Pathology, University of Illinois at Chicago, 60612, USA
    Carcinogenesis 31:1360-6. 2010
    ..The interaction between these representatives of different classes of selenoproteins was investigated. Increasing SBP1 levels in either human colorectal or breast cancer cells by transfection of an expression construct resulted in the ..
  20. pmc A yeast model of FUS/TLS-dependent cytotoxicity
    Shulin Ju
    Department of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, United States of America
    PLoS Biol 9:e1001052. 2011
    ..over-expression library identified five yeast DNA/RNA binding proteins, encoded by the yeast genes ECM32, NAM8, SBP1, SKO1, and VHR1, that rescue the toxicity of human FUS/TLS without changing its expression level, cytoplasmic ..
  21. ncbi Mouse liver selenium-binding protein decreased in abundance by peroxisome proliferators
    C S Giometti
    Biosciences Division, Argonne Laboratory, IL 60439, USA
    Electrophoresis 21:2162-9. 2000
    ..protein 2 (SBP2 formerly 56 kDa acetaminophen-binding protein, AP 56) and selenium-binding protein 1 (SBP1 formerly 56 kDa selenium-binding protein, SP 56) in mouse liver, proteins with a high degree of sequence similarity,..
  22. pmc Redox proteomic analysis of carbonylated brain proteins in mild cognitive impairment and early Alzheimer's disease
    Rukhsana Sultana
    Department of Chemistry, University of Kentucky, Lexington, KY, USA
    Antioxid Redox Signal 12:327-36. 2010
    ..CA II), heat shock protein 70 (Hsp70), mitogen-activated protein kinase I (MAPKI), and syntaxin binding protein I (SBP1) in MCI IPL...
  23. pmc Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy
    Zhen Zhang
    Laboratory of Developmental Biology, National Heart Lung and Blood Institute, Bethesda, MD 20892 1583, USA
    Proc Natl Acad Sci U S A 106:3219-24. 2009
    ..region and a second causing replacement of a highly conserved cysteine with arginine (C193R) in the gene Megf8. Megf8 is evolutionarily conserved from human to fruit fly, and is observed to be ubiquitously expressed...
  24. pmc Herbicide safener-binding protein of maize. Purification, cloning, and expression of an encoding cDNA
    J S Scott-Craig
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 116:1083-9. 1998
    ..SafBP is most abundant in the coleoptile and scarcest in the leaves, consistent with the distribution of SafBA. SBP1, a cDNA encoding SafBP, was cloned using polymerase chain reaction primers based on purified proteolytic peptides...
  25. pmc The identification of cDNAs that affect the mitosis-to-interphase transition in Schizosaccharomyces pombe, including sbp1, which encodes a spi1p-GTP-binding protein
    X He
    Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, Texas 77030, USA
    Genetics 148:645-56. 1998
    ..med1 encodes a homologue of the human Ran-binding protein, RanBP1, and has been renamed sbp1 (spi1-binding protein)...
  26. ncbi Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening
    M Nakayama
    Kazusa DNA Research Institute, 1532 3 Yana, Kisarazu, 292 0812, Japan
    Genomics 51:27-34. 1998
    ....
  27. ncbi RNase treatment of yeast and mammalian cell extracts affects in vitro substrate methylation by type I protein arginine N-methyltransferases
    A Frankel
    Department of Chemistry and Biochemistry and Molecular Biology Institute, UCLA, Los Angeles, California 90095 1569, USA
    Biochem Biophys Res Commun 259:391-400. 1999
    ..allowed us to tentatively identify the glycine- and arginine-rich (GAR) domain-containing proteins Gar1, Nop1, Sbp1, and Npl3 as major methyl-acceptors based on their known isoelectric points and apparent molecular weights...
  28. ncbi Evolutionary relationships among proteins encoded by the regulator of complement activation gene cluster
    J Krushkal
    Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA 01609 2280, USA
    Mol Biol Evol 17:1718-30. 2000
    ..membrane cofactor protein (MCP), decay accelerating factor (DAF), and the sand bass proteins, the cofactor protein (SBP1) and its homolog, the cofactor-related protein (SBCRP-1)...
  29. ncbi [Screening of the genes of hepatitis B virus PreS2 interacting proteins]
    Yin Ying Lu
    Gene Therapy Research Center, Institute of Infectious Diseases, 302nd Hospital of People s Liberation Army, Beijing 100039, China
    Zhonghua Gan Zang Bing Za Zhi 11:8-10. 2003
    ..To screen and clone the genes of proteins in hepatocytes interacting with hepatitis B virus (HBV) PreS2 by yeast-two hybridization technique...
  30. ncbi Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B
    Hideaki Fujita
    Division of Pharmaceutical Cell Biology, Kyushu University Graduate School of Pharmaceutical Sciences, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Cell Sci 117:2997-3009. 2004
    ..We have identified two SKD1-binding proteins, SBP1 and mVps2, by yeast two-hybrid screening and we assign them as mammalian class E Vps proteins...
  31. pmc Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1
    Ishara Azmi
    Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Cell Biol 172:705-17. 2006
    ..Vta1 promotes proper assembly of Vps4 and stimulates its ATPase activity through the conserved Vta1/SBP1/LIP5 region present in Vta1 homologues across evolution, including human SBP1 and Arabidopsis thaliana LIP5...
  32. pmc A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells
    Brian M Cooke
    Molecular and Cellular Rheology Laboratory, Department of Microbiology, Monash University, Victoria 3800, Australia
    J Cell Biol 172:899-908. 2006
    ..Targeted gene disruption of a Maurer's cleft protein, SBP1 (skeleton-binding protein 1), prevented IRBC adhesion because of the loss of PfEMP1 expression on the IRBC surface...
  33. pmc Identification and characterization of components of a putative petunia S-locus F-box-containing E3 ligase complex involved in S-RNase-based self-incompatibility
    Zhihua Hua
    Intercollege Graduate Degree Program in Plant Biology, Pensylvania State University, University Park, Pensylvania 16802, USA
    Plant Cell 18:2531-53. 2006
    ..We also isolated a RING-HC protein, S-RNase Binding Protein1 (Pi SBP1), almost identical to Petunia hybrida SBP1, which interacts with Pi SLFs, S-RNases, Pi CUL1-G, and an E2 ubiquitin-..
  34. pmc Distribution of novel and previously investigated virulence genes in colonizing and invasive isolates of Streptococcus agalactiae
    T C Smith
    Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
    Epidemiol Infect 135:1046-54. 2007
    ..III-3, were represented by 18 different genetic signatures and several serotypes, and that the presence of both sbp1 and rib was more predictive of invasive disease than spb1 alone...
  35. pmc The Arabidopsis putative selenium-binding protein family: expression study and characterization of SBP1 as a potential new player in cadmium detoxification processes
    Christelle Dutilleul
    Laboratoire de Physiologie Cellulaire Végétale, UMR 5168, Commissariat à l Energie Atomique CNRS Université Joseph Fourier INRA, 38054 Grenoble Cedex 9, France
    Plant Physiol 147:239-51. 2008
    ..Arabidopsis thaliana), the putative selenium-binding protein (SBP) gene family is composed of three members (SBP1-SBP3). Reverse transcription-polymerase chain reaction analyses showed that SBP1 expression was ubiquitous...
  36. doi Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer
    Tianhong Li
    Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA
    Mol Nutr Food Res 52:1289-99. 2008
    ..We identified approximately 3.5-fold significant downregulation of selenium-binding protein 1 (SBP1) in colorectal tumors compared to normal mucosa (p = 0.003)...
  37. pmc Inhibition of malaria parasite development by a cyclic peptide that targets the vital parasite protein SERA5
    W Douglas Fairlie
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Infect Immun 76:4332-44. 2008
    ..We used phage display to identify a small (14-residue) disulfide-bonded cyclic peptide (SBP1) that targets the enzyme domain of SERA5...
  38. doi Pollen proteins bind to the C-terminal domain of Nicotiana alata pistil arabinogalactan proteins
    Christopher B Lee
    Divisions of Biological Sciences, Interdisciplinary Plant Group, Christopher S Bond Life Sciences Center, University of Missouri, Columbia, Missouri 65211, USA
    J Biol Chem 283:26965-73. 2008
    ..We found that an S-RNase-binding protein (SBP1), a C2 domain-containing protein (NaPCCP), and a putative cysteine protease bound to the AGP baits...
  39. doi Clinical usefulness of the second peak of radial systolic blood pressure for estimation of aortic systolic blood pressure
    K Kohara
    Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon City, Ehime 791 0295, Japan
    J Hum Hypertens 23:538-45. 2009
    ..The radial waveform was analysed to obtain the first peak of radial SBP (SBP1), second peak of radial SBP (SBP2), radial augmentation index (AI) (radial (SBP2-DBP)/(SBP1-DBP) x 100 and aortic ..
  40. doi Sequence requirements for the export of the Plasmodium falciparum Maurer's clefts protein REX2
    Silvia Haase
    Bernhard Nocht Institute for Tropical Medicine, Malaria II, 20359 Hamburg, Germany
    Mol Microbiol 71:1003-17. 2009
    ..An N-terminal region and the transmembrane domain of the unrelated PEXEL-negative exported protein SBP1 (skeleton-binding protein 1) can functionally replace the corresponding regions in REX2, suggesting that these ..
  41. ncbi liguleless1 encodes a nuclear-localized protein required for induction of ligules and auricles during maize leaf organogenesis
    M A Moreno
    Yale University, Department of Biology, New Haven, Connecticut 06520 8104, USA
    Genes Dev 11:616-28. 1997
    ..the LG1 protein is largely novel but contains an internal domain of 77 amino acids with significant similarity to a domain present in two recently identified SQUAMOSA PROMOTER-BINDING proteins 1 and 2 (SBP1 and SBP2) in Antirhinum majus.