LRSAM1

Summary

Gene Symbol: LRSAM1
Description: leucine rich repeat and sterile alpha motif containing 1
Alias: CMT2P, RIFLE, TAL, E3 ubiquitin-protein ligase LRSAM1, Tsg101-associated ligase
Species: human

Top Publications

  1. ncbi Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding
    Ido Amit
    Department of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel
    Genes Dev 18:1737-52. 2004
  2. ncbi The lion of the union: the pelvic wound of Joshua Lawrence Chamberlain
    W J Harmon
    Wilford Hall Medical Center, Lackland Air Force Base, University of Texas Health Science Center at San Antonio, 78250, USA
    J Urol 163:713-6. 2000
  3. ncbi Regulation of potassium channel Kir 1.1 (ROMK) abundance in the thick ascending limb of Henle's loop
    C A Ecelbarger
    Division of Endocrinology, Georgetown University, Washington, DC, USA
    J Am Soc Nephrol 12:10-8. 2001
  4. ncbi Predictive value of RIFLE classification on prognosis of critically ill patients with acute kidney injury treated with continuous renal replacement therapy
    Wen xiong Li
    Department of Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
    Chin Med J (Engl) 122:1020-5. 2009
  5. ncbi Medium-term follow-up of Achilles tendon lengthening in the treatment of ankle equinus in cerebral palsy
    Frederick R Dietz
    Department of Orthopaedics Surgery, University of Iowa Hospitals and Clinics Iowa City, IA 52242, USA
    Iowa Orthop J 26:27-32. 2006
  6. ncbi Immunomorphometric studies of proteinuria in individual deep and superficial nephrons of rats
    J R Hoyer
    Department of Pediatrics at the Children s Hospital of Philadelphia, Pennsylvania 19104 4318, USA
    Lab Invest 80:1691-700. 2000
  7. ncbi RIFLE-based data collection/management system applied to a prospective cohort multicenter Italian study on the epidemiology of acute kidney injury in the intensive care unit
    Francesco Garzotto
    Departments of Intensive Care and Anesthesiology, St Bortolo Hospital, Viale Rodolfi 37, Vicenza, Italy
    Blood Purif 31:159-71. 2011
  8. ncbi Balance ability and athletic performance
    Con Hrysomallis
    Institute of Sport, Exercise and Active Living, School of Sport and Exercise Science, Victoria University, Melbourne, Victoria, Australia
    Sports Med 41:221-32. 2011
  9. ncbi [Magnetic resonance imaging and pathological evaluation of vacuum sealing drainage efficacy of early treated limb gunshot]
    Ronggang Li
    The Second Affiliated Hospital of Lanzhou University, Lanzhou Gansu, 730030, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24:335-9. 2010
  10. ncbi Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: unusual clinical associations and novel claudin16 mutation in an Egyptian family
    Mohammad Al-Haggar
    Genetics Unit, Mansoura University Children s Hospital, Mansoura, Egypt
    Clin Exp Nephrol 13:288-94. 2009

Research Grants

  1. AUTOREGULATION OF GLOMERULAR FILTRATION RATE
    Roland Blantz; Fiscal Year: 2000
  2. APPROACHES TO NATRIURETIC AND ANTIHYPERTENSIVE AGENTS
    William Wechter; Fiscal Year: 2001
  3. Pathogenesis and Treatment of Liver Disease in Transaldolase Deficiency
    Andras Perl; Fiscal Year: 2010
  4. 3D MRI-Based Modeling for Computer-Aided Right Ventricle Remodeling Surgery
    Dalin Tang; Fiscal Year: 2010
  5. Nanostructured Zirconia Ceramics for Joint Prosthetics
    ANTHONY SUTORIK; Fiscal Year: 2004
  6. MOLECULAR BIOLOGY OF TRANSALDOLASE
    Andras Perl; Fiscal Year: 2004
  7. Multiscale Model of Neural Control of Breathing
    ILYA A contact RYBAK; Fiscal Year: 2010
  8. Prevention of Kidney Stone Crystal Retention
    Jack G Kleinman; Fiscal Year: 2010
  9. Prevention of Kidney Stone Crystal Retention
    JACK KLEINMAN; Fiscal Year: 2007
  10. Development of a Total Artificial Lung
    Robert H Bartlett; Fiscal Year: 2010

Detail Information

Publications138 found, 100 shown here

  1. ncbi Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding
    Ido Amit
    Department of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel
    Genes Dev 18:1737-52. 2004
    ..We report a novel protein, Tal (Tsg101-associated ligase), whose RING finger is necessary for multiple monoubiquitylation of Tsg101...
  2. ncbi The lion of the union: the pelvic wound of Joshua Lawrence Chamberlain
    W J Harmon
    Wilford Hall Medical Center, Lackland Air Force Base, University of Texas Health Science Center at San Antonio, 78250, USA
    J Urol 163:713-6. 2000
    ..In particular the most devastating injury was a rifle shot through the pelvis rupturing the bladder and urethra...
  3. ncbi Regulation of potassium channel Kir 1.1 (ROMK) abundance in the thick ascending limb of Henle's loop
    C A Ecelbarger
    Division of Endocrinology, Georgetown University, Washington, DC, USA
    J Am Soc Nephrol 12:10-8. 2001
    The renal outer medullary potassium channel (ROMK) of the thick ascending limb (TAL) is a critical component of the counter-current multiplication mechanism...
  4. ncbi Predictive value of RIFLE classification on prognosis of critically ill patients with acute kidney injury treated with continuous renal replacement therapy
    Wen xiong Li
    Department of Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
    Chin Med J (Engl) 122:1020-5. 2009
    ..The recently proposed risk, injury, failure, loss, end-stage kidney disease (RIFLE) criteria for diagnosis and classification of AKI may provide a method for clinicians to decide the "optimal ..
  5. ncbi Medium-term follow-up of Achilles tendon lengthening in the treatment of ankle equinus in cerebral palsy
    Frederick R Dietz
    Department of Orthopaedics Surgery, University of Iowa Hospitals and Clinics Iowa City, IA 52242, USA
    Iowa Orthop J 26:27-32. 2006
    ..It was hypothesized that the use of Achilles tendon lengthening (TAL) as a treatment for spastic ankle equinus during gait results in a high rate of over-weakening of the triceps surae ..
  6. ncbi Immunomorphometric studies of proteinuria in individual deep and superficial nephrons of rats
    J R Hoyer
    Department of Pediatrics at the Children s Hospital of Philadelphia, Pennsylvania 19104 4318, USA
    Lab Invest 80:1691-700. 2000
    ..the uniformly abundant renal synthesis of Tamm-Horsfall protein (THP) in the thick ascending limb of Henle's loop (TAL)...
  7. ncbi RIFLE-based data collection/management system applied to a prospective cohort multicenter Italian study on the epidemiology of acute kidney injury in the intensive care unit
    Francesco Garzotto
    Departments of Intensive Care and Anesthesiology, St Bortolo Hospital, Viale Rodolfi 37, Vicenza, Italy
    Blood Purif 31:159-71. 2011
    ..The RIFLE and AKIN initiatives have provided a unifying definition for AKI, making possible large retrospective studies in ..
  8. ncbi Balance ability and athletic performance
    Con Hrysomallis
    Institute of Sport, Exercise and Active Living, School of Sport and Exercise Science, Victoria University, Melbourne, Victoria, Australia
    Sports Med 41:221-32. 2011
    ..Surprisingly, no studies were found that compared the balance ability of rifle shooters with other athletes...
  9. ncbi [Magnetic resonance imaging and pathological evaluation of vacuum sealing drainage efficacy of early treated limb gunshot]
    Ronggang Li
    The Second Affiliated Hospital of Lanzhou University, Lanzhou Gansu, 730030, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24:335-9. 2010
    ..To evaluate the effectiveness of vacuum sealing drainage (VSD) treating the penetrating wound in porcine extremity by MRI and pathological methods so as to provide theoretical basis for future clinical use...
  10. ncbi Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: unusual clinical associations and novel claudin16 mutation in an Egyptian family
    Mohammad Al-Haggar
    Genetics Unit, Mansoura University Children s Hospital, Mansoura, Egypt
    Clin Exp Nephrol 13:288-94. 2009
    ..is impaired tubular resorption of magnesium and calcium in the thick ascending limb of the loop of Henle (TAL) due to a genetic defect in paracellin-1 (a tight junction protein expressed in TAL)...
  11. ncbi Renal dysfunction after off-pump coronary artery bypass surgery- risk factors and preventive strategies
    Gaurab Maitra
    Consultant, Department of Anesthesiology, Perioperative Medicine and Pain, Apollo Gleneagles Hospitals, Kolkata
    Indian J Anaesth 53:401-7. 2009
    ..injury, the Acute Dialysis Quality Initiative formulated the Risk, Injury, Failure, Loss, and End-stage Kidney (RIFLE) classification...
  12. ncbi Balanced nitrogen economy as a flexible strategy on yield stabilizing and quality of aquatic food crops in wetland ecosystem
    A M Puste
    Department of Agronomy, Faculty of Agriculture, Bidhan Chandra Krishi Viswavidyalaya Agricultural University Mohanpur, 741 252, Nadia, West Bengal, India
    Sci China C Life Sci 48:980-7. 2005
    ..aquatic food crops (starch and protein-rich, most popular and remunerative) in the farmers' field of low-lying 'Tal' situation of New Alluvial Zone of Indian subtropics...
  13. ncbi Surgical treatment for rabbits' femoral arteries subjected to gunshot wounds combining with seawater immersion
    Peng Liu
    Department of Orthopaedics, Research Institute of Field Surgery and Daping Hospital, Third Military Medical University, Chongqing 400042, China
    Chin J Traumatol 8:311-6. 2005
    ..To investigate the surgical treatment methods and evaluate the outcome of gunshot wounds combining with seawater immersion in rabbits' femoral arteries...
  14. ncbi Impact of prealbumin levels on mortality in patients with acute kidney injury: an observational cohort study
    Jose Ramon Perez Valdivieso
    Department of Anesthesia and Critical Care, Clinica Universitaria, University of Navarra, Pamplona, Spain
    J Ren Nutr 18:262-8. 2008
    ..We evaluated the prognostic value of prealbumin (transthyretin) levels in patients with acute kidney injury (AKI)...
  15. ncbi Protection efficiency of hearing protectors against military noise from handheld weapons and vehicles
    R Pääkkönen
    Tampere Regional Institute of Occupational Health, P O Box 486, FIN 33101 Tampere, Finland
    Noise Health 7:11-20. 2005
    ..Commercial and military versions of earmuff noise attenuation were measured against rifle noise...
  16. ncbi Balanced nitrogen economy as a flexible strategy on yield stabilizing and quality of aquatic food crops in wetland ecosystem
    A M Puste
    Department of Agronomy, Faculty of Agriculture, Bidhan Chandra Krishi Viswavidyalaya Agricultural University Mohanpur 741 252, Nadia, West Bengal, India
    Sci China C Life Sci 48:980-7. 2005
    ..aquatic food crops (starch and protein-rich, most popular and remunerative) in the farmers' field of low-lying 'Tal' situation of New Alluvial Zone of Indian subtropics...
  17. ncbi Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis
    K Banki
    Department of Pathology, State University of New York College of Medicine, Syracuse 13210
    J Exp Med 180:1649-63. 1994
    ..was cloned and found to constitute an integral part of the coding sequence of the human transaldolase gene (TAL-H)...
  18. ncbi Wound ballistics: Minié ball vs. full metal jacketed bullets--a comparison of Civil War and Spanish-American War firearms
    Paul Joseph Dougherty
    Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI 48109, USA
    Mil Med 174:403-7. 2009
    ..This study compares the wounding characteristics of a reproduction rifle from the American Civil War to one of the Spanish-American War using the wound profile method.
  19. ncbi Na,K-ATPase activity in renal tubule cells from Milan hypertensive rats
    M L Melzi
    Department of Pediatrics, , Karolinska Institute, Stockholm, Sweden
    Am J Hypertens 2:563-6. 1989
    ..Na,K-ATPase activity in proximal convoluted tubules (PCT) cells and medullary thick ascending limb of Henle cells (TAL) from MHS and from the Milan normotensive rats (MNS)...
  20. ncbi Cloning and kidney cell-specific activity of the promoter of the murine renal Na-K-C1 cotransporter gene
    P Igarashi
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520
    J Biol Chem 271:9666-74. 1996
    ..proximal 5'-flanking region was ligated to a luciferase reporter gene and transfected into thick ascending limb (TAL) cells, a stable cell line derived from microdissected loops of Henle of the Tg(SV40E)Bri7 mouse...
  21. ncbi Prognosis and serum creatinine levels in acute renal failure at the time of nephrology consultation: an observational cohort study
    Jose Ramon Perez-Valdivieso
    Department of Anesthesia and Critical Care, Clinica Universitaria, University of Navarra, Pamplona, Spain
    BMC Nephrol 8:14. 2007
    ..renal failure (ARF), before specialized treatment begins, and in-hospital mortality, recovery of renal function, and overall mortality at 6 months, on an equal degree of ARF severity, using the RIFLE criteria, and comorbid illnesses.
  22. ncbi Implications for wildlife and humans of dietary exposure to lead from fragments of lead rifle bullets in deer shot in the UK
    Jeff Knott
    Royal Society for the Protection of Birds, The Lodge, Sandy, Bedfordshire SG19 2DL, UK
    Sci Total Environ 409:95-9. 2010
    ..Recent evidence has shown that the problem extends to terrestrial ecosystems and to fragmented rifle bullets eaten by scavengers as well as shotgun pellets...
  23. ncbi Bicarbonate transport along the loop of Henle: molecular mechanisms and regulation
    Giovambattista Capasso
    Chair of Nephrology, Research Center for Cardiovascular Diseases, School of Medicine, Second University of Naples, Italy
    J Nephrol 15:S88-96. 2002
    ..vivo microperfusion, perfusion in vitro of the S3 segment of the proximal tubule and of the thick ascending limb (TAL) of Henle's loop, as well as quantitative PCR performed on isolated TAL, has permitted the definition of key ..
  24. ncbi Preoperative estimated glomerular filtration rate and RIFLE-classified postoperative acute kidney injury predict length of stay post-coronary bypass surgery in an Australian setting
    E M Moore
    Intensive Care Unit, St Vincent s Hospital, Melbourne, Victoria, Australia
    Anaesth Intensive Care 38:113-21. 2010
    ..Postoperative acute kidney injury was categorised using serum creatinine RIFLE criteria (no acute kidney injury, risk, injury and failure)...
  25. ncbi Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study
    I Steinvall
    The Burn Unit, Department of Hand and Plastic Surgery, Linkoping University Hospital, Garnisonsvägen, Linkoping, 58185, Sweden
    Crit Care 12:R124. 2008
    ....
  26. ncbi Initiation of murine embryonic erythropoiesis: a spatial analysis
    L Silver
    University of Rochester Medical Center, Department of Pediatrics and Cancer Center, NY 14642, USA
    Blood 89:1154-64. 1997
    ..0). VYS erythropoiesis is decreased or abrogated by targeted disruption of the hematopoietic transcription factors tal-1, rbtn2, GATA-1, and GATA-2...
  27. ncbi The association of renal dysfunction and the use of aprotinin in patients undergoing congenital cardiac surgery requiring cardiopulmonary bypass
    Ana Manrique
    Department of Cardiovascular Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Anesth Analg 109:45-52. 2009
    ....
  28. ncbi Efficacy of the thin agar layer method for the recovery of stressed Cronobacter spp. (Enterobacter sakazakii)
    Tareq M Osaili
    Department of Nutrition and Food Technology, Faculty of Agriculture, Jordan University of Science and Technology, P O Box 3030, Irbid, 22110, Jordan
    J Food Prot 73:1913-8. 2010
    ..This study evaluated the efficacy of the thin agar layer (TAL) method for the recovery of Cronobacter cells that had been exposed to various stress conditions. Five strains of C...
  29. ncbi ROMK is required for expression of the 70-pS K channel in the thick ascending limb
    Ming Lu
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520 8026, USA
    Am J Physiol Renal Physiol 286:F490-5. 2004
    Apical potassium recycling is crucial for salt transport by the thick ascending limb (TAL). Loss-of-function mutations in the K channel, ROMK (Kir1...
  30. ncbi cAMP increases surface expression of NKCC2 in rat thick ascending limbs: role of VAMP
    Pablo A Ortiz
    Hypertension and Vascular Research Division, Dept of Internal Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Am J Physiol Renal Physiol 290:F608-16. 2006
    NaCl absorption by the thick ascending limb of Henle's loop (TAL) is mediated by the apical Na-K-2Cl cotransporter NKCC2. cAMP increases NaCl absorption in the TAL by stimulating NKCC2...
  31. ncbi Characterization of serum lysosomal enzymatic activities. II. Effect of lumpy skin disease in Egyptian cows
    M A Abdalla
    Department of Animal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Zagazig University, Egypt
    Dtsch Tierarztl Wochenschr 99:347-9. 1992
    ..lysosomal enzymes (LYE) in eight lumpy skin diseases (LSD) cows and same number of healthy ones were reported in Tal-El Baker village and Tal Alkabir centre, Ismailia province, Egypt...
  32. ncbi Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa
    Andras Perl
    Department of Medicine, College of Medicine, State University of New York, 750 East Adams Street, Syracuse, NY 13210, USA
    Proc Natl Acad Sci U S A 103:14813-8. 2006
    ..Here, we report that male mice lacking transaldolase (TAL)(-/-) are sterile because of defective forward motility...
  33. ncbi Transforming genes in duck hepatic carcinoma--mht(raf) and Ha-ras
    H Tan
    Department of Biochemistry and Molecular Biology, Shanghai Cancer Institute
    Sci Sin B 31:1325-32. 1988
    ..was performed with DNAs from 2 duck primary hepatic carcinomas (DHC 40K, 9K) and 1 tumor-adjacent liver tissue (TAL, 9N). Transfectants were found from 40K, 9K and 9N DNAs...
  34. ncbi Pentose phosphate pathway flux analysis for glycopeptide antibiotic vancomycin production during glucose-limited cultivation of Amycolatopsis orientalis
    Hulya Ayar-Kayali
    Faculty of Science, Department of Chemistry, Biochemistry Division, University of Dokuz Eylul, Buca, Izmir, Turkey
    Prep Biochem Biotechnol 41:94-105. 2011
    ..such as glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH), and transaldolase (TAL) activities as well as ATP- and ADP-level variations of Amycolatopsis orientalis were investigated with respect to ..
  35. ncbi Management of maxillofacial problems in self-inflicted rifle wounds
    Fuat Yuksel
    Gulhane Military Medical Academy, Haydarpasa Hospital, Department of Plastic and Reconstructive Surgery, Istanbul, Turkey
    Ann Plast Surg 53:111-7. 2004
    ..The initial anatomic reconstruction of the existing bone skeleton and the maximal use of regional tissue for cutaneous reconstruction provide an esthetic appearance that can never be duplicated by secondary reconstruction...
  36. ncbi Transaldolase: from biochemistry to human disease
    Anne K Samland
    The Institute of Microbiology, Universitat Stuttgart, Allmandring 31, Stuttgart, Germany
    Int J Biochem Cell Biol 41:1482-94. 2009
    The role of the enzyme transaldolase (TAL) in central metabolism, its biochemical properties, structure, and role in human disease is reviewed...
  37. ncbi Ultrastructural localization of antigens recognized by the monoclonal antibodies MB1, MB2, MT1, UCHL1, and TAL 1B5
    M G Butler
    Department of Histopathology, St Bartholomew s Hospital, London, United Kingdom
    Ultrastruct Pathol 12:301-5. 1988
    ..These distributions are different from that of immunoreactivity with TAL 1B5 (anti-HLA DR), which is present both on the cell membrane and in the cytoplasm...
  38. ncbi Acute kidney injury in tropical acute febrile illness in a tertiary care centre--RIFLE criteria validation
    Gopal Basu
    Department of Nephrology, Christian Medical College, Vellore, India
    Nephrol Dial Transplant 26:524-31. 2011
    Acute febrile illnesses are a common cause of tropical acute kidney injury (AKI). The incidence and severity of AKI in tropical febrile illnesses and validity of RIFLE classification are unclear.
  39. ncbi Comparison of recovery of airborne microorganisms in a dairy cattle facility using selective agar and thin agar layer resuscitation media
    Beth Ann Crozier-Dodson
    Kansas State University, Department of Animal Sciences and Industry, Manhattan 66506 1600, USA
    J Food Prot 65:1488-92. 2002
    Thin agar layer (TAL) medium was developed at Kansas State University to improve the resuscitation of injured cells and has been shown to result in higher recovery than is obtained with selective media alone for cold-, heat-, salt-, and ..
  40. ncbi Energy cost of rifle carriage in biathlon skiing
    K W Rundell
    Sport Science and Technology Division, United States Olympic Committee, Lake Placid, NY, USA
    Med Sci Sports Exerc 30:570-6. 1998
    Since biathlon racing involves cross-country skiing while carrying a minimum weight 3.5-kg rifle, energy cost for rifle carriage could be significant to race outcome...
  41. ncbi Contributions of conserved serine and tyrosine residues to catalysis, ligand binding, and cofactor processing in the active site of tyrosine ammonia lyase
    Amy C Schroeder
    The Donald Danforth Plant Science Center, St Louis, MO 63132, USA
    Phytochemistry 69:1496-506. 2008
    Tyrosine ammonia lyase (TAL) catalyzes the conversion of L-tyrosine to p-coumaric acid using a 3,5-dihydro-5-methylidene-4H-imidazole-4-one (MIO) prosthetic group...
  42. ncbi A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts
    L Vitelli
    Department of Hematology Oncology, Istituto Superiore di Sanita, 00161 Rome, Italy
    Mol Cell Biol 20:5330-42. 2000
    ..erythroblasts, generated in vitro by normal adult progenitors, contain a pentamer protein complex comprising the tal-1 transcription factor heterodimerized with the ubiquitous E2A protein and linked to Lmo2, Ldb1, and retinoblastoma ..
  43. ncbi Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy
    Sean M Bagshaw
    Division of Critical Care Medicine, University of Alberta, Edmonton, AB, Canada
    Intensive Care Med 35:871-81. 2009
    ..To describe the incidence and outcomes associated with early acute kidney injury (AKI) in septic shock and explore the association between duration from hypotension onset to effective antimicrobial therapy and AKI...
  44. ncbi Relationship between lymphocyte apoptosis and endotoxin translocation after thermal injury in rats
    Pei Yuan Xia
    Department of Pharmacy and Clinical Pharmacology, Southwestern Hospital, Third Military Medical University, Chongqing 400038, China
    World J Gastroenterol 8:546-50. 2002
    ..To investigate the relationship between lymphocyte apoptosis in peripheral blood, spleen and mesenteric lymph nodes(MLN) and endotoxin translocation after thermal injury in rats...
  45. ncbi Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications
    José António Lopes
    Department of Nephrology and Renal Transplantation, Hospital de Santa Maria, Av, Prof, Egas Moniz, Lisboa 1649 035, Portugal
    Crit Care 12:R110. 2008
    ..Injury Network (AKIN) criteria versus Risk, Injury, Failure, Loss of Kidney Function, End-stage Kidney Disease (RIFLE) criteria is currently unknown...
  46. ncbi Mutagenesis of 18 type III effectors reveals virulence function of XopZ(PXO99) in Xanthomonas oryzae pv. oryzae
    Congfeng Song
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Mol Plant Microbe Interact 23:893-902. 2010
    ..oryzae pv. oryzae belong to a family of transcription activator-like (TAL) effectors...
  47. ncbi Acute kidney injury in the intensive care unit according to RIFLE
    Marlies Ostermann
    Department of Intensive Care, Guy s and St Thomas Hospital, London, UK
    Crit Care Med 35:1837-43; quiz 1852. 2007
    To apply the RIFLE criteria "risk," "injury," and "failure" for severity of acute kidney injury to patients admitted to the intensive care unit and to evaluate the significance of other prognostic factors.
  48. ncbi Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL
    K Mutig
    Department of Anatomy, Charite Universitatsmedizin, Berlin, Germany
    Am J Physiol Renal Physiol 293:F1166-77. 2007
    ..Pronounced V(2)R signal in thick ascending limb (TAL) was corroborated functionally; phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter type 2 (NKCC2) was established ..
  49. ncbi Lineage-restricted regulation of the murine SCL/TAL-1 promoter
    E O Bockamp
    University of Cambridge, Department of Haematology, MRC Centre, UK
    Blood 86:1502-14. 1995
    The SCL/TAL-1 gene encodes a basic helix-loop-helix transcription factor that is expressed in multipotent hematopoietic progenitors before lineage commitment...
  50. ncbi RIFLE criteria for acute kidney injury in valvular surgery
    Luca Salvatore De Santo
    Chair of Cardiac Surgery, University of Foggia, Foggia, Italy
    J Heart Valve Dis 19:139-47; discussion 148. 2010
    The RIFLE classification, which defines three grades of increasing severity of acute kidney injury--risk (RIFLE R), injury (RIFLE I) and failure (RIFLE F), and two outcome classes (L, loss) and E (end-stage kidney disease)--represents a ..
  51. ncbi Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients
    Patrick Lecomte
    Department of Anaesthesiology and Critical Care Medicine, Onze Lieve Vrouw Hospital, Moorselbaan 164, 9300 Aalst, Belgium
    Crit Care 12:R154. 2008
    ..and postoperative tight control of blood glucose levels on renal function after cardiac surgery based on the Risk, Injury, Failure, Loss, and End-stage kidney failure (RIFLE) criteria, and on the need for acute postoperative dialysis.
  52. ncbi Anti-inflammatory effect of triterpenoic Acids of Eriobotrya japonica (Thunb.) Lindl. Leaf on rat model of chronic bronchitis
    Jin fang Ge
    School of Pharmacy, Anhui Medical University, Hefei 230032, Anhui, China
    Am J Chin Med 37:309-21. 2009
    ..Lindl. (TAL) on chronic bronchitis (CB) in rats...
  53. ncbi Detection of glucagon receptor mRNA in the rat proximal tubule: potential role for glucagon in the control of renal glucose transport
    J Marks
    Department of Physiology and Centre for Nephrology, Institute of Urology and Nephrology, Royal Free and University College Medical School, Middlesex Hospital, London, UK
    Clin Sci (Lond) 104:253-8. 2003
    ..renal tubular solute and fluid transport, although it is only thought to act directly on the thick ascending limb (TAL) and collecting duct (CD)...
  54. ncbi Contribution of acute kidney injury toward morbidity and mortality in burns: a contemporary analysis
    Steven G Coca
    Clinical Epidemiology Research Center, Veterans Affairs Medical Center, West Haven, CT 06516, USA
    Am J Kidney Dis 49:517-23. 2007
    ..It is not known whether milder forms of AKI have prognostic importance in burns...
  55. ncbi Effects of abomasal infusion of linseed oil on responses to glucose and insulin in holstein cows
    J A A Pires
    Department of Dairy Science, University of Wisconsin, Madison 53706, USA
    J Dairy Sci 91:1378-90. 2008
    ..design, fed to meet maintenance requirements, and infused abomasally with either linseed oil (LIN) or tallow (TAL) at a rate of 0.54 g/kg of body weight per d for 5.5 d...
  56. ncbi Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice
    Ming Lu
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520 8026, USA
    J Biol Chem 277:37881-7. 2002
    ..1; Kcnj1) gene is believed to encode the apical small conductance K(+) channels (SK) of the thick ascending limb (TAL) and cortical collecting duct (CCD)...
  57. ncbi Phase 1 study of human plasma-derived plasmin (TAL-05-00018) in hemodialysis graft occlusion
    Richard Shlansky-Goldberg
    University of Pennsylvania, Philadelphia, PA, USA
    Thromb Res 122:S16-9. 2008
    ..Percutaneous intervention involves thrombolysis with plasminogen activators, mechanical removal of thrombus, and angioplasty of the stenotic lesions...
  58. ncbi Effect of luminal atrial natriuretic peptide on chloride reabsorption in mouse cortical thick ascending limb: inhibition by endothelin
    C Bailly
    Department of Cellular Biology, CEA Saclay, Gif sur Yvette, France
    J Am Soc Nephrol 11:1791-7. 2000
    ..undertaken to investigate a possible effect of the peptide on chloride reabsorption (JCl) in thick ascending limb (TAL)...
  59. ncbi [Na-K-Cl cotransporters and "salt-sensitive" arterial hypertension]
    R P Garay
    INSERM U400,
    Arch Mal Coeur Vaiss 92:1033-8. 1999
    ..of DS rats seems to be hyperactivity of cotransporter Na-K-Cl BSC1 at the thick ascending limb of Henle's loop (TAL)...
  60. ncbi An investigation into the behaviour of air rifle pellets in ballistic gel and their interaction with bone
    G Wightman
    School of Contemporary Sciences, University of Abertay Dundee, Bell Street, Dundee DD5 3JS, Scotland, United Kingdom
    Forensic Sci Int 200:41-9. 2010
    ..The present study was therefore carried out to improve understanding of the terminal ballistic behaviour of air rifle pellets. Pellets were fired into ballistic gel under a variety of conditions...
  61. ncbi Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens
    T E Adams
    Immunology 50:613-24. 1983
    Two monoclonal antibodies, TAL-1B5 and TAL-3C3, specific for human Ia alpha-chain subunits have been produced by fusing P3/NSI/1-Ag4-1 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with purified alpha-chains...
  62. ncbi Novel insights regarding the operational characteristics and teleological purpose of the renal Na+-K+-Cl2 cotransporter (NKCC2s) splice variants
    Geneviève M Brunet
    Department of Medicine, Faculty of Medicine, Nephrology Group, L Hôtel Dieu de Research Center, Laval University, Quebec, Canada G1R 2J6
    J Gen Physiol 126:325-37. 2005
    ..polytopic protein that forms homooligomeric complexes in the apical membrane of the thick ascending loop of Henle (TAL)...
  63. ncbi The Acute Kidney Injury Network (AKIN) criteria applied in burns
    Kevin K Chung
    Clinical Division, United States Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Burn Care Res 33:483-90. 2012
    ..classification system is a modification of the previously described risk, injury, failure, loss, and end-stage (RIFLE) criteria. Among other modifications, the AKIN staging requires an absolute serum creatinine change of 0...
  64. ncbi Study of transaldolase deficiency in urine samples by capillary LC-MS/MS
    Gyorgy Vas
    SUNY Upstate Medical University, Department of Medicine, NY 13210, USA
    J Mass Spectrom 41:463-9. 2006
    Transaldolase (TAL) is a key enzyme of the pentose phosphate pathway (PPP). TAL deficiency is a newly recognized cause of liver cirrhosis...
  65. ncbi Addition of transcription activator-like effector binding sites to a pathogen strain-specific rice bacterial blight resistance gene makes it effective against additional strains and against bacterial leaf streak
    Aaron W Hummel
    Department of Plant Pathology and Microbiology, Iowa State University, Ames, IA 50011, USA
    New Phytol 195:883-93. 2012
    Xanthomonas transcription activator-like (TAL) effectors promote disease in plants by binding to and activating host susceptibility genes...
  66. ncbi Relationships between postural balance, rifle stability and shooting accuracy among novice rifle shooters
    K Mononen
    Research Institute for Olympic Sports, Jyvaskyla, Finland
    Scand J Med Sci Sports 17:180-5. 2007
    ..e., postural balance and gun barrel stability, among novice rifle shooters in intra- and inter-individual levels...
  67. ncbi Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins
    Carsten A Wagner
    Institute of Physiology, Center for Integrative Human Physiology, Univ of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Am J Physiol Renal Physiol 294:F1373-80. 2008
    ..by loss-of-function mutations in proteins mediating or regulating salt transport in the thick ascending limb (TAL) of Henle's loop...
  68. ncbi Incidence and predictors of nephrotoxicity associated with intravenous colistin in overweight and obese patients
    Timothy P Gauthier
    Department of Pharmacy Practice, Nova Southeastern University College of Pharmacy, Fort Lauderdale, Florida, USA
    Antimicrob Agents Chemother 56:2392-6. 2012
    ..Severity of acute kidney injury was defined by RIFLE (risk, injury, failure, loss, and end-stage kidney disease) criteria...
  69. ncbi Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease
    Ning Sun
    Department of Biochemistry, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Mol Biosyst 8:1255-63. 2012
    b>TAL effector nucleases (TALENs) represent a new class of artificial nucleases capable of cleaving long, specific target DNA sequences in vivo and are powerful tools for genome editing with potential therapeutic applications...
  70. ncbi Thoracic artificial lung impedance studies using computational fluid dynamics and in vitro models
    Rebecca E Schewe
    Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
    Ann Biomed Eng 40:628-36. 2012
    ..This study sought to reduce TAL impedance using computational fluid dynamics (CFD)...
  71. ncbi Structural basis for sequence-specific recognition of DNA by TAL effectors
    Dong Deng
    State Key Laboratory of Bio membrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China
    Science 335:720-3. 2012
    b>TAL (transcription activator-like) effectors, secreted by phytopathogenic bacteria, recognize host DNA sequences through a central domain of tandem repeats...
  72. ncbi Using RIFLE criteria to evaluate acute kidney injury in brain-deceased kidney donors
    Emilio Rodrigo
    Nephrology, Hospital Universitario Marques de Valdecilla, Santander, Spain
    Nephrol Dial Transplant 25:1531-7. 2010
    ..One of these strategies is the use of donors with renal dysfunction, as this is usually a reversible condition. RIFLE (risk, injury, failure, loss and end-stage renal failure) criteria were developed to standardize the definition ..
  73. ncbi [Importance of the molecular diagnosis in the screening of alpha-thalassemia]
    Domenico Dell'Edera
    Laboratorio di Genetica Medica, Presidio Ospedaliero Madonna delle Grazie, Matera
    Recenti Prog Med 102:302-6. 2011
    ..This paper highlights that in the presence of a alfa2-Tal (-α/αα), called the silent, the biochemical diagnosis turns out to be insufficient...
  74. ncbi Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease
    Bin Tang
    Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA
    Neurobiol Dis 42:459-67. 2011
    ..We qPCR-validated increases in expression of genes related to the latter category, including Lrsam1, Erp29, Nasp, Tap1, Rab9b, and Pfdn5 in R6/2(Q300) mice, changes that were not observed in R6/2 mice with shorter ..
  75. ncbi Incidence of and risk factors for colistin-associated nephrotoxicity in a large academic health system
    Jason M Pogue
    Department of Pharmacy Services, Sinai Grace Hospital, Detroit Medical Center, Michigan, USA
    Clin Infect Dis 53:879-84. 2011
    ..Recent literature, largely obtained from outside the United States, suggests a lower rate of nephrotoxicity than historically reported...
  76. ncbi Acute kidney injury in AIDS: frequency, RIFLE classification and outcome
    G B Silva Júnior
    Divisão de Nefrologia, Hospital Universitario Walter Cantidio, Faculdade de Medicina, Universidade Federal do Ceara, Fortaleza, CE, Brasil
    Braz J Med Biol Res 43:1102-8. 2010
    ..present study was to evaluate the characteristics of acute kidney injury (AKI) in AIDS patients and the value of RIFLE classification for predicting outcome...
  77. ncbi Rifle criteria for acute kidney dysfunction following liver transplantation: incidence and risk factors
    A Kundakci
    Department of Anesthesiology, Baskent University Faculty of Medicine, Ankara, Turkey
    Transplant Proc 42:4171-4. 2010
    b>RIFLE criteria have been used to determine the incidence of acute kidney dysfunction (AKD) after orthotopic liver transplantation (OLT)...
  78. ncbi A biomechanical rationale for C1-ring osteosynthesis as treatment for displaced Jefferson burst fractures with incompetency of the transverse atlantal ligament
    Heiko Koller
    Department for Traumatology and Sport Injuries, Paracelsus Medical University Salzburg, Mullner Hauptstrasse 48, 5020 Salzburg, Austria
    Eur Spine J 19:1288-98. 2010
    ..data serving evidence that C1-RO is safe in displaced JBF with proven rupture of the transverse atlantal ligament (TAL)...
  79. ncbi Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit
    James Schneider
    Department of Anesthesiology Critical Care Medicine, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    Crit Care Med 38:933-9. 2010
    To evaluate the ability of the RIFLE criteria to characterize acute kidney injury in critically ill children.
  80. ncbi Loop disorders: insights derived from defined genotypes
    Nikola Jeck
    Zentrum für Kinder und Jugendmedizin, Philipps Universitat, Marburg, Deutschland
    Nephron Physiol 118:p7-14. 2011
    ..understanding of renal salt and water wasting associated with inherited disorders of the thick ascending limb (TAL) of Henle's loop, the loop disorders...
  81. ncbi A comparison of nonoliguric and oliguric severe acute kidney injury according to the risk injury failure loss end-stage (RIFLE) criteria
    David J R Morgan
    Department of Intensive Care Medicine, Royal Perth Hospital, Perth, W A, Australia
    Nephron Clin Pract 115:c59-65. 2010
    Risk, Injury, Failure, Loss, and End-Stage (RIFLE) criteria have been proposed as a standard definition of acute kidney injury (AKI)...
  82. ncbi Activation of the bumetanide-sensitive Na+,K+,2Cl- cotransporter (NKCC2) is facilitated by Tamm-Horsfall protein in a chloride-sensitive manner
    Kerim Mutig
    Department of Anatomy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Biol Chem 286:30200-10. 2011
    Active transport of NaCl across thick ascending limb (TAL) epithelium is accomplished by Na(+),K(+),2Cl(-) cotransporter (NKCC2)...
  83. ncbi Acute kidney injury in adult postcardiotomy patients with extracorporeal membrane oxygenation: evaluation of the RIFLE classification and the Acute Kidney Injury Network criteria
    Xiaolei Yan
    Intensive Care Unit, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, PR China
    Eur J Cardiothorac Surg 37:334-8. 2010
    ..The RIFLE (the Risk of renal failure, Injury to the kidney, Failure of kidney function, Loss of kidney function and End-..
  84. ncbi [Molecular recognition code between pathogenic bacterial TAL-effectors and host target genes: a review]
    Yanqiang Li
    Key Laboratory of Crop Genetics and Breeding, Ministry of Agriculture, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China
    Sheng Wu Gong Cheng Xue Bao 27:1132-41. 2011
    As the pathogenic bacterial virulence and avirulence factors, transcription activator like (TAL) effectors of Xanthomonas can resulted in the host diseases or resistance responses...
  85. ncbi Acute kidney injury classification: comparison of AKIN and RIFLE criteria
    Chih Hsiang Chang
    Department of Nephrology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan
    Shock 33:247-52. 2010
    ..renal failure, injury to kidney, failure of kidney function, loss of kidney function, and end-stage renal failure (RIFLE) classification system...
  86. ncbi Evaluation of sepsis/systemic inflammatory response syndrome, acute kidney injury, and RIFLE criteria in two tertiary hospital intensive care units in Turkey
    Itir Yegenaga
    Department of Internal Medicine, Kocaeli University Medical School, Kocaeli, Turkey itiryegenaga hotmail com
    Nephron Clin Pract 115:c276-82. 2010
    ..Patients were classified as those without AKI (n = 60; 43.20%) and those with AKI (n = 79; 56.80%) based on the RIFLE (Risk, Injury, Failure, Loss, End-stage renal disease) criteria...
  87. ncbi Effects of physical and geochemical heterogeneities on mineral transformation and biomass accumulation during biostimulation experiments at Rifle, Colorado
    Li Li
    Lawrence Berkeley National Laboratory, Earth Sciences Division, 1 Cyclotron Road, MS 90 1116, Berkeley, CA 94720, United States
    J Contam Hydrol 112:45-63. 2010
    ..distributions of mineral precipitates and biomass accumulated during a biostimulation field experiment near Rifle, Colorado...
  88. ncbi Prospective multicenter study on epidemiology of acute kidney injury in the ICU: a critical care nephrology Italian collaborative effort (NEFROINT)
    P Piccinni
    Department of Intensive Care and Anesthesiology, S Bortolo Hospital, Vicenza, Italy
    Minerva Anestesiol 77:1072-83. 2011
    ..The RIFLE consensus definition has provided a unifying definition for AKI leading to large retrospective studies in ..
  89. ncbi The characterization of transaldolase gene tal from Pichia stipitis and its heterologous expression in Fusarium oxysporum
    Jin Xia Fan
    Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China
    Mol Biol Rep 38:1831-40. 2011
    The 972 bp length of transaldolase gene tal was cloned from Pichia stipitis CICC1960, encoding a 323 amino acid protein with a calculated molecular mass of 35.36 kDa and isoelectric point of 5.20...
  90. ncbi Tarsal-less peptides control Notch signalling through the Shavenbaby transcription factor
    Jose I Pueyo
    School of Life Sciences, University of Sussex, Falmer, Brighton, UK
    Dev Biol 355:183-93. 2011
    ..Here we show that the non-canonical tarsal-less (tal) gene (also known as pri), which encodes for four small related peptides, is expressed in the N-activated region ..
  91. ncbi Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery
    Charles E Hobson
    Department of Medicine, Division of Thoracic and Cardiovascular Surgery, University of Florida College of Medicine, Gainesville, Fla 32610 0286, USA
    Circulation 119:2444-53. 2009
    ..We report the relationship between long-term mortality and AKI with small changes in serum creatinine during hospitalization after various cardiothoracic surgery procedures...
  92. ncbi T-cell acute lymphoblastic leukemia--the associated gene SCL/tal codes for a 42-Kd nuclear phosphoprotein
    A N Goldfarb
    University of Minnesota Hospital Department of Laboratory Medicine and Pathology, Minneapolis
    Blood 80:2858-66. 1992
    SCL/tal is a putative oncogene originally identified through its involvement in the translocation t(1;14)(p32;q11) present in the leukemic cell line DU.528...
  93. ncbi Cytotoxic T lymphocyte mediated recognition of human pancreatic cancer cells
    Matthias Peiper
    Chirurgische Klinik, Universitätsklinikum Eppendorf, Hamburg, Germany
    Int J Cancer 99:88-92. 2002
    ..Tumor-associated lymphocytes (TAL) and peripheral blood monocytes (PBMC) were isolated from pancreatic cancer patients...
  94. ncbi Effect of short-term vs. long-term elevation of dietary protein intake on responsiveness of rat thick ascending limbs to peptide hormones
    David L Goldstein
    Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA
    Comp Biochem Physiol A Mol Integr Physiol 133:359-66. 2002
    ..hypertrophy resulted from enlargement of the inner stripe of the outer medulla, site of the thick ascending limbs (TAL), and TAL from HP rats were larger in diameter...
  95. ncbi Bicarbonate reabsorption and NHE-3 expression: abundance and activity are increased in Henle's loop of remnant rats
    Giovambattista Capasso
    Nephrology and Research Centre for Cardiovascular Diseases, Second University of Naples, Naples, Italy
    Kidney Int 62:2126-35. 2002
    ..of bicarbonate reabsorption along the loop of Henle (LOH) is localized at the level of the thick ascending limb (TAL) and is mainly dependent on the presence of luminal Na+-H+ exchanger (NHE-3)...
  96. ncbi Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene
    Hanna K A Mikkola
    Department of Pediatric Oncology, Children s Hospital and the Dana Farber Cancer Institute, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA
    Nature 421:547-51. 2003
    ..Specification of HSCs from mesoderm during embryonic development requires the stem cell leukaemia SCL/tal-1 gene product...
  97. ncbi Interaction of an aromatic dibromoisothiouronium derivative with the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum
    M C Berman
    Division of Chemical Pathology, Health Science Faculty, University of Cape Town, Observatory 7925, Cape Town, South Africa
    Biochemistry 42:3556-66. 2003
    Isothiouronium compounds [Hoving, S., Bar-Shimon, M., Tijmes, J. J., Goldshleger, R., Tal, D. M., and Karlish, S. J. (1995) J. Biol. Chem...
  98. ncbi Regulation of sodium transporters in the thick ascending limb of rat kidney: response to angiotensin II
    Tae Hwan Kwon
    The Water and Salt Research Center, University of Aarhus, Denmark
    Am J Physiol Renal Physiol 285:F152-65. 2003
    ..for 7 days was examined with respect to the abundance and subcellular localization of key thick ascending limb (TAL) Na+ transporters. Rats were on a fixed intake of Na+ and water and treated with 0, 12...
  99. ncbi NF-kappaB activation in premalignant mouse tal-1/scl thymocytes and tumors
    Jennifer O'Neil
    Department of Cancer Biology, University of Massachusetts Medical School, Worcester, USA
    Blood 102:2593-6. 2003
    b>TAL-1/SCL activation is a common genetic event in pediatric T-cell acute lymphoblastic leukemia (T-ALL)...
  100. ncbi Erythropoietin protects against ischaemic acute renal injury
    David A Vesey
    Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
    Nephrol Dial Transplant 19:348-55. 2004
    ..The aim of the present study was to determine whether EPO administration is also renoprotective in both in vitro and in vivo models of ischaemic acute renal failure...
  101. ncbi Restoration of tumor specific human leukocyte antigens class I-restricted cytotoxicity by dendritic cell stimulation of tumor infiltrating lymphocytes in patients with advanced ovarian cancer
    A D Santin
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, UAMS Medical Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Int J Gynecol Cancer 14:64-75. 2004
    Despite the large number of potentially cytotoxic tumor-infiltrating (TIL) and tumor-associated (TAL) lymphocytes accumulated in the peritoneal cavity ascitic fluid and tumor tissue, advanced ovarian cancer is a progressive disease, ..

Research Grants68

  1. AUTOREGULATION OF GLOMERULAR FILTRATION RATE
    Roland Blantz; Fiscal Year: 2000
    ..The elements critical to TGF adaptation are a) changes in loop of Henle - thick ascending limb (TAL) reabsorptive capacity, b) macula densa signal transmission and c) adaptations of the glomerular hemodynamic ..
  2. APPROACHES TO NATRIURETIC AND ANTIHYPERTENSIVE AGENTS
    William Wechter; Fiscal Year: 2001
    ..Based on the very high potency of LLU-alpha inhibiting the 70 pS K+ channel of TAL cells of the loop of Henle, it is now known where this receptor resides...
  3. Pathogenesis and Treatment of Liver Disease in Transaldolase Deficiency
    Andras Perl; Fiscal Year: 2010
    ..The preliminary results indicate that deficiency of transaldolase (TAL, encoded by the TALDO1 genomic locus), an enzyme of the pentose phosphate pathway (PPP), is an important cause of ..
  4. 3D MRI-Based Modeling for Computer-Aided Right Ventricle Remodeling Surgery
    Dalin Tang; Fiscal Year: 2010
    ..The MRI's to be used for this study are clinically indicated studies as part of the care of these patients and are currently obtained under an approved protocol where Dr. Tal Geva is the principal investigator.
  5. Nanostructured Zirconia Ceramics for Joint Prosthetics
    ANTHONY SUTORIK; Fiscal Year: 2004
    ..S. supplier of toughened zirconia hip joints in the U.S. but no longer produces them. Tal Materials has learned to produce large quantities of very high quality nanosized 3YSZ powders using controlled ..
  6. MOLECULAR BIOLOGY OF TRANSALDOLASE
    Andras Perl; Fiscal Year: 2004
    DESCRIPTION (Copied from Applicant Abstract): Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) which generates two essential metabolites: ribose 5-phosphate for nucleotide synthesis and NADPH for biosynthetic ..
  7. Multiscale Model of Neural Control of Breathing
    ILYA A contact RYBAK; Fiscal Year: 2010
    ..Smith, NINDS, NIH, intramural), mathematics, system analysis and bioengineering (Alona Ben-Tal, Massey University, NZ), and computational neuroscience and neural control (Ilya A. Rybak, Drexel University)...
  8. Prevention of Kidney Stone Crystal Retention
    Jack G Kleinman; Fiscal Year: 2010
    ..Polyanions and small to intermediate MW polymers containing other functional groups that may interfere with crys- tal attachment will be tested for their ability to inhibit calcium oxalate crystal deposition in rats treated with ..
  9. Prevention of Kidney Stone Crystal Retention
    JACK KLEINMAN; Fiscal Year: 2007
    ..Polyanions and small to intermediate MW polymers containing other functional groups that may interfere with crys- tal attachment will be tested for their ability to inhibit calcium oxalate crystal deposition in rats treated with ..
  10. Development of a Total Artificial Lung
    Robert H Bartlett; Fiscal Year: 2010
    ..An implantable, total artificial lung (TAL) that could function for 3-6 months would allow more patients to undergo successful lung transplantation, just as ..
  11. Development of a Total Artificial Lung
    Robert Bartlett; Fiscal Year: 2009
    ..An implantable, total artificial lung (TAL) that could function for 3-6 months would allow more patients to undergo successful lung transplantation, just as ..
  12. Development of a Total Artificial Lung
    Robert Bartlett; Fiscal Year: 2009
    ..An implantable, total artificial lung (TAL) that could function for 3-6 months would allow more patients to undergo successful lung transplantation, just as ..
  13. Development of a Total Artificial Lung
    Robert H Bartlett; Fiscal Year: 2010
    ..An implantable, total artificial lung (TAL) that could function for 3-6 months would allow more patients to undergo successful lung transplantation, just as ..
  14. ALCOHOL AND CELL ADHESION
    MICHAEL CHARNESS; Fiscal Year: 2007
    ..Because the brains of children with L1 mutations resemble those of children with tal alcohol syndrome, it is possible that inhibition of L1-mediated cell adhesion contributes to the eratogenic effects ..
  15. INTRAOPERATIVE MEASUREMENT IN CEREBRAL PALSY SURGERY
    Richard Lieber; Fiscal Year: 2003
    ..prospective clinical study which compares two methods for equinus deformity correction: tendoachilles lengthening (TAL) and gastrocnemius-soleus recession (GSR, "Strayer" procedure)...
  16. Regulation of HIV transcription by Tat and P-TEPb
    TSAFI PE ERY; Fiscal Year: 2004
    ..P-TEFb (cyclin T1/CDK9) is a cellular transcription elongation factor that cooperates with the viral protein Tal to attain processive transcription of the HIV genome...
  17. Transcriptional Control of Hematopoietic Stem Cells
    EMERY BRESNICK; Fiscal Year: 2005
    ..HoxB4, Bmi 1, beta-catenin, TAL-1 and GATA-2 transcription factors control HSC self-renewal and/or function...
  18. BIOCHEMICAL AND BIOPHYSICAL NATURE OF CLAUDIN-16 AND CLAUDIN-19 CHANNELS
    Jianghui Hou; Fiscal Year: 2010
    ..We have found that the two claudins co-localize in the thick ascending limb (TAL), interact and form a cation-selective protein complex...
  19. MOLECULAR BIOLOGY OF TRANSALDOLASE
    Andras Perl; Fiscal Year: 1999
    ..We have cloned the human transaldolase (TAL-H) cDNA, the genomic locus, produced a functional recombinant protein, and generated specific antibodies...
  20. Molecular Mechanisms of Tissue Stem Cell Plasticity
    Stuart Orkin; Fiscal Year: 2004
    ..Aim 3 will assess whether expression of a hematopoietic (SCL/tal-1) or myogenic (MyoD) regulatory gene alters in vivo HSC or muscle stem cell plasticity...