Genomes and Genes
Gene Symbol: KCNK5
Description: potassium channel, subfamily K, member 5
Alias: K2p5.1, TASK-2, TASK2, K2P5.1 potassium channel, TWIK-related acid-sensitive K(+) channel 2, TWIK-related acid-sensitive K+ channel 2, acid-sensitive potassium channel protein TASK-2, potassium channel subfamily K member 5, potassium channel, subfamily K, member 1 (TASK-2)
Publications134 found, 100 shown here
- Upregulation of K2P5.1 potassium channels in multiple sclerosisStefan Bittner
Department of Neurology, University of Wurzburg, Wurzburg, Munster, Germany
Ann Neurol 68:58-69. 2010Activation of T cells critically depends on potassium channels. We here characterize the impact of K(2P)5.1 (KCNK5; TASK2), a member of the 2-pore domain family of potassium channels, on T-cell function and demonstrate its putative ..
- Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5)Christoph H Kindler
Attending Physician, Department of Anesthesia, University Clinics, Kantonsspital, CH 4031 Basel, Switzerland
J Pharmacol Exp Ther 306:84-92. 2003..of local anesthetics on members of this ion channel family, we heterologously expressed the 2P K+ channels TASK-2 (KCNK5), TASK-1 (KCNK3), and chimeric TASK-1/TASK-2 channels in oocytes of Xenopus laevis...
- Tandem-pore domain potassium channels are functionally expressed in retinal (Müller) glial cellsS N Skatchkov
CMBN, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamon, Puerto Rico 00960 6032
Glia 53:266-76. 2006....
- The effects of huperzine A and IDRA 21 on visual recognition memory in young macaquesLudise Malkova
Department of Pharmacology and the Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, 3900 Reservoir Rd NW, Washington, DC 20007, USA
Neuropharmacology 60:1262-8. 2011..b>Task 2 included, in each of 24 trials, a list of six objects presented in succession...
- Localization of the tandem pore domain K+ channel KCNK5 (TASK-2) in the rat central nervous systemAnja Gabriel
Department of Anesthesia and Operative Intensive Care Medicine, University of Koln, 50924, Koln, Germany
Brain Res Mol Brain Res 98:153-63. 2002..The 2P K+ channel TASK-2 (also named KCNK5) is sensitive to changes in extracellular pH, inhibited by local anesthetics and activated by volatile anesthetics...
- TASK-2 is expressed in proximal neurons in the rat retinaXiao Min Zhang
Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
Neuroreport 20:946-50. 2009..In AII glycinergic amacrine cells, however, only faint punctuate staining, if any, was seen. In addition, ganglion cells were also intensely labeled by TASK-2...
- Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentrationKarin M Gerstin
Department of Anesthesia and Perioperative Care, University of California, San Francisco 94110, USA
Anesth Analg 96:1345-9, table of contents. 2003..MAC) needed to prevent movement in response to a noxious stimulus in 50% of adult mice lacking functional KCNK5 potassium channel subunits and compared these results with those for heterozygous and wild-type mice...
- Effect of unaccustomed eccentric exercise on proprioception of the knee in weight and non-weight bearing tasksCarolina Vila-Chã
Centre for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7, D 3, DK 9220, Aalborg, Denmark
J Electromyogr Kinesiol 21:141-7. 2011..In conclusion, eccentric exercise of the quadriceps impairs proprioception of the knee both immediately after and 24h post exercise, but only in non-weight bearing tasks...
- Decision making in pathological gambling: a comparison between pathological gamblers, alcohol dependents, persons with Tourette syndrome, and normal controlsAnna E Goudriaan
Amsterdam Institute for Addiction Research, Academic Medical Centre, University of Amsterdam, The Netherlands
Brain Res Cogn Brain Res 23:137-51. 2005..Deficits in decision making and feedback processing in PG should be addressed in treatment and incorporated more explicitly in theoretical models of PG...
- fMRI of parents of children with Asperger Syndrome: a pilot studySimon Baron-Cohen
Department of Psychiatry, Autism Research Centre, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge CB2 2AH, UK
Brain Cogn 61:122-30. 2006..People with autism or Asperger Syndrome (AS) show altered patterns of brain activity during visual search and emotion recognition tasks. Autism and AS are genetic conditions and parents may show the 'broader autism phenotype.'..
- Protective effects of Nicotiflorin on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model ratsJin ling Huang
Department of Pharmacology, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Pharmacol Biochem Behav 86:741-8. 2007..These results suggest that Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats...
- Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channelsNicole Bobak
University of Muenster, Department of neurology Inflammatory disorders of the nervous system and neurooncology, Domagkstr, 13, 48149 Muenster, Germany
Biochim Biophys Acta 1808:2036-44. 2011..This study explores a putative role of the newly identified K(2P) channels (TASK1, TASK2, TASK3 and TRESK) along with the voltage-gated potassium channel K(V)1...
- Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and peripheryA D Medhurst
Neuroscience Research, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Essex CM19 5AW, Harlow, UK
Brain Res Mol Brain Res 86:101-14. 2001..Furthermore, identification of common areas of expression may help identify which channels, if any, associate to form heteromeric K+ channel complexes...
- Activation of the TASK-2 channel after cell swelling is dependent on tyrosine phosphorylationSigne Skyum Kirkegaard
Section of Cell and Developmental Biology, Dept of Biology, The August Krogh Bldg, Univ of Copenhagen, 13, Universitetsparken, DK 2100, Copenhagen, Denmark
Am J Physiol Cell Physiol 299:C844-53. 2010..It is suggested that the cytokine receptor-coupled JAK/STAT pathway is upstream of the swelling-induced phosphorylation and activation of TASK-2 in EATC...
- The stage-specific effect of alcohol on human information processingTom A Schweizer
Department of Psychology, University of Waterloo, Waterloo, ON, Canada
Psychopharmacology (Berl) 178:52-7. 2005..quick succession, performance on the second task is increasingly degraded as the temporal gap between task 1 and task 2 decreases...
- Evaluation of BioCreAtIvE assessment of task 2Christian Blaschke
Bioalma SL, Ronda de Poniente 4 2nd floor, Tres Cantos, E 28760, Madrid, Spain
BMC Bioinformatics 6:S16. 2005..In order to make text mining tools useable in real world scenarios, for instance to assist database curators during annotation of protein function, comparisons and evaluations of different approaches on full text articles are needed...
- Enhanced muscle fatigue occurs in male but not female ASIC3-/- miceLynn A Burnes
Graduate Program in Physical Therapy and Rehabilitation Science, Pain Research Program, Neuroscience Graduate Program, University of Iowa, Iowa City, IA 52242, USA
Am J Physiol Regul Integr Comp Physiol 294:R1347-55. 2008..two exercise protocols to measure exercise-induced muscle fatigue: (fatigue task 1, three 1-h runs; fatigue task 2, three 30-min runs)...
- When underadditivity of factor effects in the Psychological Refractory Period paradigm implies a bottleneck: evidence from psycholinguisticsDerek Besner
University of Waterloo, Waterloo, Ontario, Canada
Q J Exp Psychol (Hove) 62:2222-34. 2009..If the effect of a factor manipulated in Task 2 decreases as the stimulus onset asynchrony (SOA) between tasks decreases (underadditivity), the normative ..
- Evidence for automatic on-line adjustments of hand orientation during natural reaching movements to stationary targetsN Gosselin-Kessiby
Departement de Physiologie, Universite de Montreal, Montreal, Quebec, Canada
J Neurophysiol 99:1653-71. 2008..In letter-posting task 2, subjects first aligned their hand to the angle of the target and then reached to it with the instruction not to ..
- Evidence for a proprioception-based rapid on-line error correction mechanism for hand orientation during reaching movements in blind subjectsNadia Gosselin-Kessiby
Departement de Physiologie, Universite de Montreal, Montreal, Quebec, Canada H3C 3J7
J Neurosci 29:3485-96. 2009..In letter-posting task 2, blind subjects first aligned their hand to the orientation of the target and then subsequently reached to the ..
- Deficits in facial emotion perception in adults with recent traumatic brain injuryRobin E A Green
Toronto Rehabilitation Institute, 550 University Avenue Room 1004, Toronto, Ont, Canada M5G 2A2
Neuropsychologia 42:133-41. 2004..Journal of Neuroscience 20(7) (2000) 2683] that damage to white matter tracts should give rise to emotion perception deficits...
- Fast, but error-prone, responses during acute alcohol intoxication: effects of stimulus-response mapping complexityTom A Schweizer
Department of Psychology, University of Waterloo, Waterloo, Ontario, Canada
Alcohol Clin Exp Res 28:643-9. 2004..This study used a psychological refractory period paradigm to investigate the effect of alcohol on the central, cognitive stage of information processing when task complexity is manipulated by altering stimulus-response compatibility...
- Global synchronization in the theta band during mental imagery of navigation in humansYang Li
System Emotional Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama ken, Toyama 930 0194, Japan
Neurosci Res 65:44-52. 2009..Theta oscillation appears to play an important role in large-scale synchronization to form the functional neuronal networks required for mental navigation...
- Biomechanical investigation of ambulatory training in patients with acetabular dysplasiaAkira Kanai
Department of Physical Therapy, Toyohashi SOZO University School of Rehabilitation, 20 1 Matsusita, Ushikawa cho, Toyohashi City, Aichi, Japan
Gait Posture 28:52-7. 2008..In exercise task 2, walking speed was changed in three stages from 60 steps/min (s-gait), 90 steps/min (n-gait), and 120 steps/min (f-..
- Synergists activation pattern of the quadriceps muscle differs when performing sustained isometric contractions with different EMG biofeedbackNicolas Place
INSERM ERM 207 Motricité Plasticité, Faculte des Sciences du Sport, Universite de Bourgogne, Dijon Cedex, France
Exp Brain Res 174:595-603. 2006....
- Brazilian Portuguese version of the Iowa Gambling Task: transcultural adaptation and discriminant validityLeandro Fernandes Malloy-Diniz
Neuropsychology and Neurosciences Research Group, Universidade Fumec, Belo Horizonte, MG, Brazil
Rev Bras Psiquiatr 30:144-8. 2008..The aim of this work was to adapt the Iowa Gambling Task to Brazilian Portuguese, compare it with the original version and assess its validity...
- The locus coeruleus involves in consolidation and memory retrieval, but not in acquisition of inhibitory avoidance learning taskBehrooz Khakpour-Taleghani
Cellular and Molecular Research Center and Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Behav Brain Res 189:257-62. 2008..In conclusion, it seems that the nucleus locus coeruleus does not affect acquisition while it involves in the memory consolidation and retrieval of inhibitory avoidance learning task...
- Genetic covariance among measures of information processing speed, working memory, and IQM Luciano
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia
Behav Genet 31:581-92. 2001..26 in females, 0.13 in males; genotypic: 0.34). A significant part of the genetic variance (43%) in IQ was not related to either choice RT or delayed response performance, and may represent higher order cognitive processes...
- Functional MRI of language in aphasia: a review of the literature and the methodological challengesBruce Crosson
Department of Veterans Affairs Rehabilitation Research and Development Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida, USA
Neuropsychol Rev 17:157-77. 2007..While the promise of fMRI in the study of aphasia is great, there is much work to be done before this technique will be a useful clinical tool...
- Neuroprotective effect of remacemide hydrochloride in a perforant pathway stimulation model of status epilepticus in the ratT Halonen
A I Virtanen Institute for Molecular Sciences, University of Kuopio, Finland
Epilepsy Res 34:251-69. 1999..did remacemide or carbamazepine treatment alleviate spatial memory impairment determined in a Morris water-maze task 2 weeks after PP stimulation...
- Viewer perspective affects central bottleneck requirements in spatial translation tasksElizabeth A Franz
Department of Psychology, Otago University, Dunedin, New Zealand
J Exp Psychol Hum Percept Perform 34:398-412. 2008..Dual tasks consisted of tone discriminations (Task 1) and spatial translations (Task 2) using PRP methods with different manipulations on perceptual and response demands...
- Effects of 7 Hz-modulated 450 MHz electromagnetic radiation on human performance in visual memory tasksJ Lass
Biomedical Engineering Centre, Tallinn Technical University, Ehitajate tee 5, 19086 Tallinn, Estonia
Int J Radiat Biol 78:937-44. 2002..The aim was to examine low-level 7 Hz-modulated 450 MHz radiation effects on human performance in visually presented neuropsychological tasks associated with attention and short-term memory...
- Asymmetric activation of motor cortex controlling human anterior digastric muscles during speech and target-directed jaw movementsPaul F Sowman
Research Centre for Human Movement Control, Discipline of Physiology, School of Molecular and Biomedical Sciences, The University of Adelaide, Adelaide 5005, South Australia, Australia
J Neurophysiol 102:159-66. 2009..speaking a single word; 3) visually guided, nonspeech jaw movement that matched the jaw kinematics recorded during task 2; and 4) reciting a sentence...
- Assessment of cognitive function in the heterozygous reeler mouseDilja D Krueger
Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, Ribicoff Research Facilities, CMHC, 34 Park Street, New Haven, CT 06508, USA
Psychopharmacology (Berl) 189:95-104. 2006..However, the effect of reelin haploinsufficiency on one of the cardinal symptoms of schizophrenia, the impairment of prefrontal-cortex-dependent cognitive function, has yet to be determined...
- Effect of fixation tasks on multifocal visual evoked potentialsAlessandra Martins
Save Sight Institute, Department of Ophthalmology and Eye Health, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia
Clin Experiment Ophthalmol 33:499-504. 2005..Three different foveal fixation conditions were utilized involving varying levels of task complexity. A more complex visual fixation task has been known to suppress peripheral signals in subjective testing...
- Predictors of driving exposure and avoidance in a field study of older drivers from the state of MarylandDavid E Vance
Department of Psychology, Center for Translational Research on Aging and Mobility, University of Alabama at Birmingham, 35294 2100, USA
Accid Anal Prev 38:823-31. 2006..A performance-based assessment, which included the Gross Impairment Screening battery and task 2 of the UFOV test, was completed by participants...
- Effects of an acute alpha-lactalbumin manipulation on mood and food hedonics in high- and low-trait anxiety individualsEllen Verschoor
Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Br J Nutr 104:595-602. 2010..On both the test days, participants completed a stress-inducing task 2 h after the lunch. Mood and appetite were assessed using visual analogue scales...
- Multisession, dual-task psychological refractory period practice benefits older and younger adults equallyPhilip A Allen
Department of Psychology, University of Akron, Akron, OH 44325 4301, USA
Exp Aging Res 35:369-99. 2009..Task 1 involved tone discrimination and Task 2 involved simultaneous letter-matching...
- Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zincCatherine E Clarke
Department of Biological Sciences, Imperial College London, Exhibition Road, London SW7 2AZ, UK
J Physiol 560:51-62. 2004..Therefore it is possible that inhibition of IK(SO) in cerebellar granule cells by synaptically released zinc may have important physiological consequences...
- An evaluation of GO annotation retrieval for BioCreAtIvE and GOAEvelyn B Camon
European Molecular Biology Laboratory, European Bionformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
BMC Bioinformatics 6:S17. 2005..BioCreAtIvE task 2 was an experiment to test if automatically derived classification using information retrieval and extraction could ..
- The psychological refractory period: evidence for age differences in attentional time-sharingP A Allen
Department of Psychology, Cleveland State University, Ohio 44115, USA
Psychol Aging 13:218-29. 1998..psychological refractory period (PRP) experiments in which the stimulus onset asynchrony (SOA) between Task 1 and Task 2 was 150 ms, 250 ms, 600 ms, and 1,100 ms for both younger and older adults. H...
- Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transportRichard Warth
Institute of Physiology, Universitatsstrasse 31, 93053 Regensburg, Germany
Proc Natl Acad Sci U S A 101:8215-20. 2004The acid- and volume-sensitive TASK2 K+ channel is strongly expressed in renal proximal tubules and papillary collecting ducts...
- High resolution spatiotemporal analysis of the contingent negative variation in simple or complex motor tasks and a non-motor taskR Q Cui
Department of Clinical Neurology, University of Vienna, Wahringer Gurtel 18 20, A 1090, Vienna, Austria
Clin Neurophysiol 111:1847-59. 2000....
- Rhythmic and discrete elements in multi-joint coordinationDagmar Sternad
Department of Kinesiology, The Pennsylvania State University, 266 Rec Hall, University Park, PA 16803, USA
Brain Res 989:152-71. 2003..It was this rhythmic activity that posed the direct constraints on the initiation of the discrete movement...
- Virtual reality flexible cystoscopy: a validation studyJ Shah
Academic Surgical Unit, Imperial College of Science, Technology and Medicine, St Mary s Hospital, London, UK
BJU Int 90:828-32. 2002..To validate a flexible cystoscopy simulator by determining if it could differentiate between expert and novice cystoscopists...
- pH sensing in the two-pore domain K+ channel, TASK2Michael J Morton
School of Biomedical Sciences, Medical and Dental Building, University of Leeds, Leeds LS2 9NQ, United Kingdom
Proc Natl Acad Sci U S A 102:16102-6. 2005b>TASK2 is a member of the two-pore domain K(+) channel family that plays a role in acid-base homeostasis; TASK2 knockout animals have plasma electrolyte patterns typical of the human clinical condition of renal tubular acidosis...
- The psychological refractory period in Parkinson's diseaseS Hsieh
Department of Psychology, National Chung Cheng University, Taiwan, ROC
Percept Mot Skills 91:893-902. 2000..The stimulus onset asynchrony (SOA) between Task 1 and Task 2 was 50 msec., 150 msec., and 650 msec...
- Effect of flat insoles with different Shore A values on posture stability in diabetic neuropathyJ A Van Geffen
Center for Rehabilitation, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Prosthet Orthot Int 31:228-35. 2007..It was found that prescribing insoles with a low Shore A value (15 degrees), compared to insoles with a higher Shore A value (30 degrees) has no significant negative effect on posture stability in patients with a diabetic neuropathy...
- Mining protein function from text using term-based support vector machinesSimon B Rice
Faculty of Life Sciences, University of Manchester, UK
BMC Bioinformatics 6:S22. 2005..We participated in Task 2, which addressed assigning Gene Ontology terms to human proteins and selecting relevant evidence from full-text ..
- Three-dimensional in vivo quantification of knee kinematics in cerebral palsyFrances T Sheehan
Physical Disabilities Branch, National Institutes of Health, National Institute of Child Health and Human Development and the Clinical Center, National Institutes of Health, Bethesda, MD 20892 1604, USA
Clin Orthop Relat Res 466:450-8. 2008..Fast phase contrast MRI may allow differentiation of patellofemoral and tibiofemoral function in various functional subtypes of cerebral palsy, providing insights into its management...
- Task completion time: Objective tool for assessment of technical skills in laparoscopic simulator for urology traineesShashi K Mishra
Department of Urology and Nephrology, Muljibhai Patel Society for Research in Nephrourology, Muljibhai Patel Urological Hospital, Nadiad 387 001, Gujarat, India
Indian J Urol 24:35-8. 2008..Laparoscopic surgical simulation is a valuable training tool for urology trainees...
- Effects of selective inhibition of N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasksKrzysztof Lukawski
Department of Pathophysiology, Medical University of Lublin, Jaczewskiego 8, 20 090 Lublin, Poland
Eur J Pharmacol 579:202-7. 2008..In the Y-maze task, MK-801 (0.1 mg/kg i.p.) impaired alternation behavior and considerably increased locomotion in the Y-maze and locomotor activity test. These results indicate that NAALADase inhibition may impair alternation behavior...
- Event-related potentials evoked by multi-feature conflict under different attentive conditionsYuping Wang
Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053 PR China
Exp Brain Res 148:451-7. 2003..In task 1, subjects attended to the color of the stimuli and ignored the other attributes. In task 2, they were asked to attend to both color and global shape of stimuli and disregard the local shape...
- [Analysis of interference effects in simultaneous processing of 2 problems]T Schubert
Institut fur Psychologie, Humboldt Universitat Berlin
Z Exp Psychol 43:625-56. 1996..A well known result is that reaction time on task 2 (Rt2) increases with decreasing overlap of the two tasks...
- Incidental memory of differently processed odorsL Hvastja
Dipartimento di Psicologia Università di Trieste
Percept Mot Skills 85:235-44. 1997..test had to evaluate the intensity of each odor (Task 1), to judge the similarity of each odor to mint (Task 2), or to score each odor for pleasantness and sourness (Task 3)...
- The countermanding task revisited: fast stimulus detection is a key determinant of psychophysical performanceEmilio Salinas
Department of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1010, USA
J Neurosci 33:5668-85. 2013..The results suggest that manipulations of the countermanding task often cause changes in perceptual detection processes, and not necessarily in inhibition...
- Men's preference for the ovulating female is triggered by subtle face shape differencesCora Bobst
Institute of Psychology, University of Bern, Muesmattstrasse 45, 3012 Bern, Switzerland
Horm Behav 62:413-7. 2012..Thirty-six male participants were asked to choose the more attractive (Task 1), the more caring (Task 2), and the more flirtatious face (Task 3)...
- Beyond generalized hair cells: molecular cues for hair cell typesIsrat Jahan
University of Iowa, Department of Biology, College of Liberal Arts and Sciences, 143 BB, Iowa City, IA 52242, USA
Hear Res 297:30-41. 2013..Importantly, the molecular means to modify the Atoh1 expression are at least partially understood and can be readily implemented in the attempts to regenerate specific types of HCs...
- Driver performance while texting: even a little is too muchJoshua D McKeever
Department of Psychology, Drexel University, Philadelphia, PA 19104, USA
Traffic Inj Prev 14:132-7. 2013..To examine the impact of text messaging and other in-car behaviors on driving performance under simple and naturalistic road conditions in a driving simulator...
- Loss of semantic associative categories in patients with Alzheimer's diseaseDomenico Passafiume
Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
Appl Neuropsychol Adult 19:305-11. 2012..These data confirm prior research showing the semantic association is differently impaired in AD patients...
- Investigation of the role of TASK-2 channels in rat pulmonary arteries; pharmacological and functional studies following RNA interference proceduresMónika Gönczi
Faculty of Life Sciences, University of Manchester, Manchester, M13 PT, UK
Br J Pharmacol 147:496-505. 2006....
- Acoustic cue integration in speech intonation recognition with cochlear implantsShu Chen Peng
Division of Ophthalmic, Neurological, and Ear, Nose and Throat Devices, Office of Device Evaluation, U S Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD 20993, USA
Trends Amplif 16:67-82. 2012..In Task 2, the same listeners' perceptual cue weighting in question-statement identification was assessed using ..
- Expression of K2P channels in sensory and motor neurons of the autonomic nervous systemAlba Cadaveira-Mosquera
Department of Functional Biology, Faculty of Biology, University of Vigo, Campus Lagoas Marcosende, 36310, Vigo, Spain
J Mol Neurosci 48:86-96. 2012..Our results strongly suggest that TRESK and TREK channels are important modulators of the sensorial and motor information flowing through the autonomic nervous system, probably exerting a strong influence on vagal reflexes...
- Demonstrating emotional processing differences in psychopathy using affective ERP modulationNathaniel E Anderson
MIND Research Network, Albuquerque, New Mexico 87131, USA
Psychophysiology 49:792-806. 2012..not task relevant (Task 1) followed by a condition directing attention to the categorization of emotional content (Task 2)...
- Blood flow velocity in middle cerebral artery during visuo-motor tasks using a mirror: a transcranial Doppler studyRaphael Bene
University Department of Neurology, Reference Center for Neurovascular Disorders, Ministry of Health and Social Welfare of the Republic of Croatia, Sestre Milosrdnice University Hospital, Zagreb, Croatia
Acta Clin Croat 48:305-10. 2009..than during the illusion of motor hand activation (task 3) and less than during direct vision of hand flexion (task 2, +6.3% baseline value; P = 0.005)...
- Two coupled motor recovery protocols are better than one: electromyogram-triggered neuromuscular stimulation and bilateral movementsJames H Cauraugh
Motor Behavior Laboratory, University of Florida, Gainesville 32611, USA
Stroke 33:1589-94. 2002..With the use of established motor control theories, the present study investigated electromyogram (EMG)-triggered neuromuscular stimulation and bilateral coordination training...
- Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behaviorFabrice Jollant
Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
Neuroimage 51:1275-81. 2010..2009). In comparison to affective controls, suicide attempters showed 1) poorer performance on the gambling task 2) decreased activation during risky relative to safe choices in left lateral orbitofrontal and occipital cortices 3)..
- Time course of natural killer cell activity and lymphocyte proliferation in response to two acute stressors in healthy menD L Delahanty
Pittsburgh Cancer Institute, University of Pittsburgh, Pennsylvania 15213 3412, USA
Health Psychol 15:48-55. 1996..Inspection of the data suggested that this interaction was due to a reduction in proliferation in both stressor groups during the task period...
- Storage and retrieval of addition facts: the role of number comparisonB Butterworth
Department of Psychology, University College London, UK
Q J Exp Psychol A 54:1005-29. 2001..explained by the model; Task 1 was a number naming task to assess the contribution of the pronunciation stage; Task 2 was a magnitude comparison task to assess the contribution, if any, of the comparison stage...
- Does dorsal processing require central capacity? More evidence from the PRP paradigmMarkus Janczyk
Department of Psychology, Dortmund University of Technology, Emil Figge Strasse, Dortmund, Germany
Exp Brain Res 203:89-100. 2010..In particular, response times to task 2 (the grasping task) increased the more the two tasks overlapped in time, i.e...
- Modularity beyond perception: evidence from the PRP paradigmHagit Magen
Department of Psychology, Hebrew University, Mt Scopus, Jerusalem, 91905, Israel
J Exp Psychol Hum Percept Perform 36:395-414. 2010..Task 1 in all experiments was a tone discrimination task. In Experiments 1 to 3, Task 2 was a variation of either the Stroop or the flanker tasks...
- Stimulus-response compatibility and psychological refractory period effects: implications for response selectionMei Ching Lien
Department of Psychological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Psychon Bull Rev 9:212-38. 2002..In particular, the response-selection bottleneck (RSB) model assumes that the processing of Task 1 and Task 2 comprises two separate streams and that the PRP effect is due to a bottleneck located at response selection...
- Emotional processing in Parkinson's disease. A study using functional transcranial doppler sonographyE Troisi
Fondazione Santa Lucia IRCCS, Via Ardeatina 306, 00179 Roma, Italy
J Neurol 249:993-1000. 2002..cerebral arteries (MCA) during a rest condition and when viewing non emotional (tasks 1 and 3) and emotional (task 2) slide sequences. The study included 12 PD patients and 12 healthy subjects...
- Activity-dependent modulation of synaptic transmission in the intact human motor cortex revealed with transcranial magnetic stimulationClaudio Bonato
IRCCS Centro S Giovanni di Dio, Fatebenefratelli, Laboratorio di Neurofisiologia, Brescia, Italy
Cereb Cortex 12:1057-62. 2002..Possible anatomo-functional mechanisms involved in this activity-dependent modulation of MI excitability are discussed...
- TASK-1, TASK-2, TASK-3 and TRAAK immunoreactivities in the rat carotid bodyYoshio Yamamoto
Laboratory of Veterinary Anatomy, Faculty of Agriculture, Gifu University, 501 1193, Gifu, Japan
Brain Res 950:304-7. 2002..Our results indicate that TASK-1 immunoreactivity was ubiquitously distributed in many cell types and immunoreactivities for TASK-2, TASK-3 and TRAAK were cell type specific distribution patterns in the rat carotid body...
- Age differences in overlapping-task performance: evidence for efficient parallel processing in older adultsPhilip A Allen
Department of Psychology, The University of Akron, Ohio 44325, USA
Psychol Aging 17:505-19. 2002..discrimination task (triangle or rectangle) for Task 1 (T1) and a lexical-decision task (word or nonword) for Task 2 (T2) were used...
- Neural activation patterns during working memory tasks and OSA disease severity: preliminary findingsKristen H Archbold
University of Arizona College of Nursing, Tucson, AZ, USA
J Clin Sleep Med 5:21-7. 2009..A secondary aim was to explore the possible relation between OSA severity (apnea/hypopnea index) and BOLD-fMRI signal patterns...
- All-or-none bottleneck versus capacity sharing accounts of the psychological refractory period phenomenonMike Tombu
Department of Psychology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada N2L 3G1
Psychol Res 66:274-86. 2002..RT1 will increase with decreasing SOA and that the slope of the RT1 SOA effect will depend upon the difficulty of task 2. Subjects were required to perform a tone pitch judgement and shape-matching task in rapid succession...
- Nonautomatic emotion perception in a dual-task situationDave Tomasik
University of New Mexico, Albuquerque, NM 87131, USA
Psychon Bull Rev 16:282-8. 2009..Task 1 required an auditory discrimination (tone vs. noise), whereas Task 2 required a discrimination between happy and angry faces...
- Spatial frequency-specific effects on the attentional bias: Evidence for two attentional systemsVaughan V W Singh
Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
Cortex 47:547-56. 2011..Our data are consistent with the idea that the attentional bias results from right-dominant control mechanisms of stimulus-driven attention potentially interacting with voluntary control mechanisms...
- Under- and over-estimation: a bi-directional mapping process between symbolic and non-symbolic representations of number?Virginie Crollen
Unité de Neurosciences Cognitives NESC, Universite Catholique de Louvain, Belgium
Exp Psychol 58:39-49. 2011..We discussed these empirical data by showing how they can be accounted by the bi-directional mapping hypothesis (Castronovo & Seron, 2007)...
- The influence of dietary and genetic cues on the ability of rats to discriminate between the urinary odors of MHC-congenic miceR E Brown
Department of Psychology, Dalhousie University, Halifax, Nova Scotia, Canada
Physiol Behav 60:365-72. 1996..and maintained on the same diet (task 1), individual mice differing at the MHC and maintained on different diets (task 2), individual mice of the same MHC type maintained on the same diet (task 3), or individual mice of the same MHC ..
- Possible overlapping potentials of the auditory P50 in humans: factor analysis of middle latency auditory evoked potentialsH Ninomiya
Department of Neuropsychiatry, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Electroencephalogr Clin Neurophysiol 104:23-30. 1997..These results suggest that the P50 in humans consists of overlapping potentials and that a part of the potential might relate to a motor response process...
- Coherent oscillations in monkey motor cortex and hand muscle EMG show task-dependent modulationS N Baker
Sobell Department of Neurophysiology, Institute of Neurology, London, UK
J Physiol 501:225-41. 1997..They are discernable in the EMG of active muscles, and show a consistent task-dependent modulation...
- Exploring cross-task compatibility in perceiving and producing facial expressions using electromyographyEllen Otte
Institute of Psychology I, RWTH Aachen University, Aachen, Germany
Acta Psychol (Amst) 138:187-92. 2011..In one task, participants were asked to produce a smile or a frown (Task 2) in response to a tone stimulus...
- The architecture of cross-hemispheric communication in the aging brain: linking behavior to functional and structural connectivitySimon W Davis
Center for Cognitive Neuroscience, Duke University, Durham, NC 27708, USA
Cereb Cortex 22:232-42. 2012....
- Identification and functional characterization of ion channels in CD34(+) hematopoietic stem cells from human peripheral bloodKyoung Sun Park
Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 790 784, Korea
Mol Cells 32:181-8. 2011..3, Kv7.1, Nav1.7, TASK2, TALK2, TWIK2, TRPC4, TRPC6, TRPM2, TRPM7, and TRPV2...
- Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filterLeandro Zúñiga
Centro de Estudios Cientificos, Valdivia, Chile
PLoS ONE 6:e16141. 2011..Our data, therefore, strongly suggest that a cycle of protonation/deprotonation of pH(o)-sensing arginine 224 side chain gates the TASK-2 channel by electrostatically tuning the conformational stability of its selectivity filter...
- Children with SLI use argument structure cues to learn verbsJ B Oetting
Department of Communication Sciences and Disorders, Louisiana State University, Baton Rouge 70803 2606, USA
J Speech Lang Hear Res 42:1261-74. 1999..In Task 1, we examined children's use of cues to interpret novel verbs while viewing single action scenes. In Task 2, we examined the role of cues for novel verb interpretation and retention through a story viewing task...
- Non-invasive brain stimulation enhances fine motor control of the hemiparetic ankle: implications for rehabilitationSangeetha Madhavan
Department of Physical Therapy, University of Illinois, 1919 W Taylor St, Chicago, IL 60612, USA
Exp Brain Res 209:9-17. 2011..The results provide a basis for examining whether this enhanced ankle control can be induced in patients with greater impairments and whether enhanced control of a single or multiple lower limb joints improves hemiparetic gait patterns...
- Perceived fatigue after mental work: an experimental evaluation of a fatigue inventoryE Ahsberg
Department for Work and Health, National Institute for Working Life, Stockholm, Sweden
Ergonomics 43:252-68. 2000..Men and women did not differ significantly with respect to their ratings. No clear-cut physiological reactions were found to correlate with ratings of fatigue. The results indicate the validity of the mental dimension of the SOFI...
- Potassium leak channels and the KCNK family of two-P-domain subunitsS A Goldstein
Department of Pediatrics and Cellular and Molecular Physiology, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536, USA
Nat Rev Neurosci 2:175-84. 2001..Even though two-P-domain channels are widespread and essential, they were hidden from sight in plain view--our most basic questions remain to be answered...
- Objects and events as determinants of parallel processing in dual tasks: evidence from the backward compatibility effectRavid Ellenbogen
Department of Psychology, Ben Gurion University of the Negev, Beer Sheva, Israel, 84105
J Exp Psychol Hum Percept Perform 37:152-67. 2011..is a major index of parallel processing in dual tasks and is related to the dependency of Task 1 performance on Task 2 response codes (Hommel, 1998)...
- Dual-task interference: the effects of verbal cognitive tasks on upright postural stability in Parkinson's diseaseJ D Holmes
School of Occupational Therapy, The University of Western Ontario, London, ON, Canada N6G 1H1
Parkinsons Dis 2010:696492. 2010..Ironically, this overconstraint may place the participant at greater risk for a fall...
- Stroop interference is affected in inhibition of returnA B Vivas
Department of Psychology, City Liberal Studies Affiliated Institution of the University of Sheffield, Thessaloniki, Greece
Psychon Bull Rev 8:315-23. 2001..These results agree with the idea that inhibitory tagging, occurring in IOR, affects the efficiency with which color words compete for responses in Stroop-like situations...
- Upregulated TWIK-related acid-sensitive K+ channel-2 in neurons and perivascular astrocytes in the hippocampus of experimental temporal lobe epilepsyJi Eun Kim
Department of Anatomy and Neurobiology and Institute of Epilepsy Research, College of Medicine, Hallym University, Chunchon, South Korea
Epilepsia 50:654-63. 2009....
- Stability of output effects from motor cortex to forelimb muscles in primatesDarcy M Griffin
Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
J Neurosci 29:1915-27. 2009..This study further validates the use of StTA for mapping and other studies of cortical motor output...
- An investigation of the effects of relative probability of old and new test items on the neural correlates of successful and unsuccessful source memoryKaia L Vilberg
Center for the Neurobiology of Learning and Memory, and Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 3800, USA
Neuroimage 45:562-71. 2009..They then performed a source memory test with four response options: studied in task 1, studied in task 2, old but unsure of the study task, and new...
- Neural correlates of emotional working memory in patients with mild cognitive impairmentKatrin Döhnel
Department of Psychiatry and Psychotherapy, University of Regensburg, Universitatsstrasse 84, D 93053 Regensburg, Germany
Neuropsychologia 46:37-48. 2008..This increase in precuneus activity, combined with a behavioural facilitation effect, may indicate a mechanism to compensate disease related processes in aMCI...
- Contextual control by function and form of transfer of functionsDavid R Perkins
Psychology Department, University of Louisiana, Lafayette 70504 3131, USA
J Exp Anal Behav 88:87-102. 2007..For Task 1, function transfer, responding to C and D stimuli as subjects had to B stimuli, was reinforced. For Task 2, function transfer was reinforced for C stimuli but punished for D stimuli...
- Patients with Parkinson's disease can successfully remember to execute delayed intentionsMareike Altgassen
Department of Psychology, University of Zurich, Zurich, Switzerland
J Int Neuropsychol Soc 13:888-92. 2007..Data also suggest that a reduced working memory capacity plays an important role in this process. Findings are discussed in terms of conceptual, methodological, and clinical implications...
- IMAGING AND MODELING THERAPEUTIC MECHANISMS OF ACTIONPeter Fox; Fiscal Year: 2003....
- Auditory Perception of Drug Names: Neighborhood EffectsBruce Lambert; Fiscal Year: 2006..abstract_text> ..
- Engineered Spores as Fluorogenic Biological Indicators for Sterility TestingBoris Rotman; Fiscal Year: 2007..b>Task 2. Evaluate the biological indicator prototype by comparing it with conventional biological indicators using spore ..
- EVALUATOR TRAINING MANIKIN FOR SPASTICITY AND STRENGTHDAVID ENGSBERG; Fiscal Year: 2003..b>Task 2: Test the SSKAT...
- Fully Ambulatory Hot Flash Monitoring SystemROBERT LACKEY; Fiscal Year: 2005..b>Task 2 Ambulatory System Performance in Home Setting - This task will characterize the performance of the PhiloMetron ..
- Motor, Vestibular, and Mnemonic Interactions in Directional Heading PerceptionsJEFFREY STEVEN TAUBE; Fiscal Year: 2010..Learning how spatial information is processed in the rat brain will provide clues about the complex nature of spatial processes in humans. ..
- Motor, Vestibular, and Mnemonic Interactions in Directional Heading PerceptionsJEFFREY TAUBE; Fiscal Year: 2009..Learning how spatial information is processed in the rat brain will provide clues about the complex nature of spatial processes in humans. ..
- Development of a Miniaturized EMG Telemetry SystemJohn Standeven; Fiscal Year: 2001..A miniature transmitter and receiver from Ramsey Electronics will form the nucleus of this unit. Task 2: Test the single channel EMG unit...
- Motor, Vestibular, and Mnemonic Interactions in Directional Heading PerceptionsJEFFREY TAUBE; Fiscal Year: 2009..Learning how spatial information is processed in the rat brain will provide clues about the complex nature of spatial processes in humans. ..
- Creating Research Files from CMS Data for Integration with Survey DataThomas MaCurdy; Fiscal Year: 2007..MDS and Medicaid); (3) conduct a pilot project demonstrating the effectiveness of the linkage approach created in Task 2; (4) work with CMS and our project survey partners?which include HRS, PSID and NLTCS?to establish protocols that ..
- Transcatheter Intra-arterial Perfusion MRI Monitoring of Liver Tumor EmbolizationANDREW CHRISTIAN LARSON; Fiscal Year: 2010..b>Task 2: To test the hypothesis that TRIP-MRI contrast dose can be optimized intra-procedurally to permit short wash-out ..
- Emotional Reactivity of Intimate Partner AbusersJULIA BABCOCK; Fiscal Year: 2003..abstract_text> ..
- MARKERS FOR STEM CELL-LIKE COLONIC CRYPT BASE CELLSBruce Boman; Fiscal Year: 2004..AIM 2: To determine gene expression patterns and levels for SCE marker genes in abnormal crypts, (FAP crypts). Task 2: compare gene expression levels and patterns in purified whole crypts from FAP vs...
- MANAGED CARE, FINANCIAL INCENTIVE & PHYSICIAN PRACTICECarol Simon; Fiscal Year: 2002..b>Task 2: Linked survey of physicians and practices: 2000 physicians and 2000 practice-level decision-makers in 5 states to ..
- Glycerol Kinase Deficiency as a Model to Understand Met*Katrina Dipple; Fiscal Year: 2005..transcriptome analysis in the whole animal model using the glycerol kinase knock-out (gyk k/o) mouse (Specific Aim/Task 2)...
- Affective Dispositions and Attention to Emotion Info.RANDALL LARSEN; Fiscal Year: 2004....
- Radio Frequency Motion Tracking SystemDAVID ENGSBERG; Fiscal Year: 2003..Virtual movement of the transmitting antenna creates a Doppler shift in the signal at the receiver sensor. Task 2: Evaluation of the 2D device...