Genomes and Genes
Gene Symbol: KCNK5
Description: potassium channel, two pore domain subfamily K, member 5
Alias: K2p5.1, KCNK5b, TASK-2, TASK2, K2P5.1 potassium channel, TWIK-related acid-sensitive K(+) channel 2, TWIK-related acid-sensitive K+ channel 2, acid-sensitive potassium channel protein TASK-2, potassium channel subfamily K member 5, potassium channel, subfamily K, member 1 (TASK-2), potassium channel, subfamily, member 5 (KCNK5)
Publications146 found, 100 shown here
- Upregulation of K2P5.1 potassium channels in multiple sclerosisStefan Bittner
Department of Neurology, University of Wurzburg, Wurzburg, Munster, Germany
Ann Neurol 68:58-69. 2010Activation of T cells critically depends on potassium channels. We here characterize the impact of K(2P)5.1 (KCNK5; TASK2), a member of the 2-pore domain family of potassium channels, on T-cell function and demonstrate its putative ..
- Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5)Christoph H Kindler
Attending Physician, Department of Anesthesia, University Clinics, Kantonsspital, CH 4031 Basel, Switzerland
J Pharmacol Exp Ther 306:84-92. 2003..of local anesthetics on members of this ion channel family, we heterologously expressed the 2P K+ channels TASK-2 (KCNK5), TASK-1 (KCNK3), and chimeric TASK-1/TASK-2 channels in oocytes of Xenopus laevis...
- Tandem-pore domain potassium channels are functionally expressed in retinal (Müller) glial cellsS N Skatchkov
CMBN, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamon, Puerto Rico 00960 6032
Glia 53:266-76. 2006....
- The effects of huperzine A and IDRA 21 on visual recognition memory in young macaquesLudise Malkova
Department of Pharmacology and the Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, 3900 Reservoir Rd NW, Washington, DC 20007, USA
Neuropharmacology 60:1262-8. 2011..b>Task 2 included, in each of 24 trials, a list of six objects presented in succession...
- Localization of the tandem pore domain K+ channel KCNK5 (TASK-2) in the rat central nervous systemAnja Gabriel
Department of Anesthesia and Operative Intensive Care Medicine, University of Koln, 50924, Koln, Germany
Brain Res Mol Brain Res 98:153-63. 2002..The 2P K+ channel TASK-2 (also named KCNK5) is sensitive to changes in extracellular pH, inhibited by local anesthetics and activated by volatile anesthetics...
- TASK-2 is expressed in proximal neurons in the rat retinaXiao Min Zhang
Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
Neuroreport 20:946-50. 2009..In AII glycinergic amacrine cells, however, only faint punctuate staining, if any, was seen. In addition, ganglion cells were also intensely labeled by TASK-2...
- Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentrationKarin M Gerstin
Department of Anesthesia and Perioperative Care, University of California, San Francisco 94110, USA
Anesth Analg 96:1345-9, table of contents. 2003..MAC) needed to prevent movement in response to a noxious stimulus in 50% of adult mice lacking functional KCNK5 potassium channel subunits and compared these results with those for heterozygous and wild-type mice...
- Effect of unaccustomed eccentric exercise on proprioception of the knee in weight and non-weight bearing tasksCarolina Vila-Chã
Centre for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7, D 3, DK 9220, Aalborg, Denmark
J Electromyogr Kinesiol 21:141-7. 2011..In conclusion, eccentric exercise of the quadriceps impairs proprioception of the knee both immediately after and 24h post exercise, but only in non-weight bearing tasks...
- fMRI of parents of children with Asperger Syndrome: a pilot studySimon Baron-Cohen
Department of Psychiatry, Autism Research Centre, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge CB2 2AH, UK
Brain Cogn 61:122-30. 2006..People with autism or Asperger Syndrome (AS) show altered patterns of brain activity during visual search and emotion recognition tasks. Autism and AS are genetic conditions and parents may show the 'broader autism phenotype.'..
- Decision making in pathological gambling: a comparison between pathological gamblers, alcohol dependents, persons with Tourette syndrome, and normal controlsAnna E Goudriaan
Amsterdam Institute for Addiction Research, Academic Medical Centre, University of Amsterdam, The Netherlands
Brain Res Cogn Brain Res 23:137-51. 2005..Deficits in decision making and feedback processing in PG should be addressed in treatment and incorporated more explicitly in theoretical models of PG...
- Protective effects of Nicotiflorin on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model ratsJin ling Huang
Department of Pharmacology, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Pharmacol Biochem Behav 86:741-8. 2007..These results suggest that Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats...
- Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channelsNicole Bobak
University of Muenster, Department of neurology Inflammatory disorders of the nervous system and neurooncology, Domagkstr, 13, 48149 Muenster, Germany
Biochim Biophys Acta 1808:2036-44. 2011..This study explores a putative role of the newly identified K(2P) channels (TASK1, TASK2, TASK3 and TRESK) along with the voltage-gated potassium channel K(V)1...
- Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and peripheryA D Medhurst
Neuroscience Research, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Essex CM19 5AW, Harlow, UK
Brain Res Mol Brain Res 86:101-14. 2001..Furthermore, identification of common areas of expression may help identify which channels, if any, associate to form heteromeric K+ channel complexes...
- Activation of the TASK-2 channel after cell swelling is dependent on tyrosine phosphorylationSigne Skyum Kirkegaard
Section of Cell and Developmental Biology, Dept of Biology, The August Krogh Bldg, Univ of Copenhagen, 13, Universitetsparken, DK 2100, Copenhagen, Denmark
Am J Physiol Cell Physiol 299:C844-53. 2010..It is suggested that the cytokine receptor-coupled JAK/STAT pathway is upstream of the swelling-induced phosphorylation and activation of TASK-2 in EATC...
- The stage-specific effect of alcohol on human information processingTom A Schweizer
Department of Psychology, University of Waterloo, Waterloo, ON, Canada
Psychopharmacology (Berl) 178:52-7. 2005..quick succession, performance on the second task is increasingly degraded as the temporal gap between task 1 and task 2 decreases...
- Enhanced muscle fatigue occurs in male but not female ASIC3-/- miceLynn A Burnes
Graduate Program in Physical Therapy and Rehabilitation Science, Pain Research Program, Neuroscience Graduate Program, University of Iowa, Iowa City, IA 52242, USA
Am J Physiol Regul Integr Comp Physiol 294:R1347-55. 2008..two exercise protocols to measure exercise-induced muscle fatigue: (fatigue task 1, three 1-h runs; fatigue task 2, three 30-min runs)...
- Evaluation of BioCreAtIvE assessment of task 2Christian Blaschke
Bioalma SL, Ronda de Poniente 4 2nd floor, Tres Cantos, E 28760, Madrid, Spain
BMC Bioinformatics 6:S16. 2005..In order to make text mining tools useable in real world scenarios, for instance to assist database curators during annotation of protein function, comparisons and evaluations of different approaches on full text articles are needed...
- When underadditivity of factor effects in the Psychological Refractory Period paradigm implies a bottleneck: evidence from psycholinguisticsDerek Besner
University of Waterloo, Waterloo, Ontario, Canada
Q J Exp Psychol (Hove) 62:2222-34. 2009..If the effect of a factor manipulated in Task 2 decreases as the stimulus onset asynchrony (SOA) between tasks decreases (underadditivity), the normative ..
- Global synchronization in the theta band during mental imagery of navigation in humansYang Li
System Emotional Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama ken, Toyama 930 0194, Japan
Neurosci Res 65:44-52. 2009..Theta oscillation appears to play an important role in large-scale synchronization to form the functional neuronal networks required for mental navigation...
- Synergists activation pattern of the quadriceps muscle differs when performing sustained isometric contractions with different EMG biofeedbackNicolas Place
INSERM ERM 207 Motricité Plasticité, Faculte des Sciences du Sport, Universite de Bourgogne, Dijon Cedex, France
Exp Brain Res 174:595-603. 2006....
- Evidence for a proprioception-based rapid on-line error correction mechanism for hand orientation during reaching movements in blind subjectsNadia Gosselin-Kessiby
Departement de Physiologie, Universite de Montreal, Montreal, Quebec, Canada H3C 3J7
J Neurosci 29:3485-96. 2009..In letter-posting task 2, blind subjects first aligned their hand to the orientation of the target and then subsequently reached to the ..
- Evidence for automatic on-line adjustments of hand orientation during natural reaching movements to stationary targetsN Gosselin-Kessiby
Departement de Physiologie, Universite de Montreal, Montreal, Quebec, Canada
J Neurophysiol 99:1653-71. 2008..In letter-posting task 2, subjects first aligned their hand to the angle of the target and then reached to it with the instruction not to ..
- Fast, but error-prone, responses during acute alcohol intoxication: effects of stimulus-response mapping complexityTom A Schweizer
Department of Psychology, University of Waterloo, Waterloo, Ontario, Canada
Alcohol Clin Exp Res 28:643-9. 2004..This study used a psychological refractory period paradigm to investigate the effect of alcohol on the central, cognitive stage of information processing when task complexity is manipulated by altering stimulus-response compatibility...
- Biomechanical investigation of ambulatory training in patients with acetabular dysplasiaAkira Kanai
Department of Physical Therapy, Toyohashi SOZO University School of Rehabilitation, 20 1 Matsusita, Ushikawa cho, Toyohashi City, Aichi, Japan
Gait Posture 28:52-7. 2008..In exercise task 2, walking speed was changed in three stages from 60 steps/min (s-gait), 90 steps/min (n-gait), and 120 steps/min (f-..
- Deficits in facial emotion perception in adults with recent traumatic brain injuryRobin E A Green
Toronto Rehabilitation Institute, 550 University Avenue Room 1004, Toronto, Ont, Canada M5G 2A2
Neuropsychologia 42:133-41. 2004..Journal of Neuroscience 20(7) (2000) 2683] that damage to white matter tracts should give rise to emotion perception deficits...
- Brazilian Portuguese version of the Iowa Gambling Task: transcultural adaptation and discriminant validityLeandro Fernandes Malloy-Diniz
Neuropsychology and Neurosciences Research Group, Universidade Fumec, Belo Horizonte, MG, Brazil
Rev Bras Psiquiatr 30:144-8. 2008..The aim of this work was to adapt the Iowa Gambling Task to Brazilian Portuguese, compare it with the original version and assess its validity...
- Functional MRI of language in aphasia: a review of the literature and the methodological challengesBruce Crosson
Department of Veterans Affairs Rehabilitation Research and Development Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida, USA
Neuropsychol Rev 17:157-77. 2007..While the promise of fMRI in the study of aphasia is great, there is much work to be done before this technique will be a useful clinical tool...
- Effects of 7 Hz-modulated 450 MHz electromagnetic radiation on human performance in visual memory tasksJ Lass
Biomedical Engineering Centre, Tallinn Technical University, Ehitajate tee 5, 19086 Tallinn, Estonia
Int J Radiat Biol 78:937-44. 2002..The aim was to examine low-level 7 Hz-modulated 450 MHz radiation effects on human performance in visually presented neuropsychological tasks associated with attention and short-term memory...
- Neuroprotective effect of remacemide hydrochloride in a perforant pathway stimulation model of status epilepticus in the ratT Halonen
A I Virtanen Institute for Molecular Sciences, University of Kuopio, Finland
Epilepsy Res 34:251-69. 1999..did remacemide or carbamazepine treatment alleviate spatial memory impairment determined in a Morris water-maze task 2 weeks after PP stimulation...
- The locus coeruleus involves in consolidation and memory retrieval, but not in acquisition of inhibitory avoidance learning taskBehrooz Khakpour-Taleghani
Cellular and Molecular Research Center and Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Behav Brain Res 189:257-62. 2008..In conclusion, it seems that the nucleus locus coeruleus does not affect acquisition while it involves in the memory consolidation and retrieval of inhibitory avoidance learning task...
- Genetic covariance among measures of information processing speed, working memory, and IQM Luciano
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia
Behav Genet 31:581-92. 2001..26 in females, 0.13 in males; genotypic: 0.34). A significant part of the genetic variance (43%) in IQ was not related to either choice RT or delayed response performance, and may represent higher order cognitive processes...
- Viewer perspective affects central bottleneck requirements in spatial translation tasksElizabeth A Franz
Department of Psychology, Otago University, Dunedin, New Zealand
J Exp Psychol Hum Percept Perform 34:398-412. 2008..Dual tasks consisted of tone discriminations (Task 1) and spatial translations (Task 2) using PRP methods with different manipulations on perceptual and response demands...
- Asymmetric activation of motor cortex controlling human anterior digastric muscles during speech and target-directed jaw movementsPaul F Sowman
Research Centre for Human Movement Control, Discipline of Physiology, School of Molecular and Biomedical Sciences, The University of Adelaide, Adelaide 5005, South Australia, Australia
J Neurophysiol 102:159-66. 2009..speaking a single word; 3) visually guided, nonspeech jaw movement that matched the jaw kinematics recorded during task 2; and 4) reciting a sentence...
- Effect of fixation tasks on multifocal visual evoked potentialsAlessandra Martins
Save Sight Institute, Department of Ophthalmology and Eye Health, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia
Clin Experiment Ophthalmol 33:499-504. 2005..Three different foveal fixation conditions were utilized involving varying levels of task complexity. A more complex visual fixation task has been known to suppress peripheral signals in subjective testing...
- Effects of an acute alpha-lactalbumin manipulation on mood and food hedonics in high- and low-trait anxiety individualsEllen Verschoor
Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Br J Nutr 104:595-602. 2010..On both the test days, participants completed a stress-inducing task 2 h after the lunch. Mood and appetite were assessed using visual analogue scales...
- Assessment of cognitive function in the heterozygous reeler mouseDilja D Krueger
Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, Ribicoff Research Facilities, CMHC, 34 Park Street, New Haven, CT 06508, USA
Psychopharmacology (Berl) 189:95-104. 2006..However, the effect of reelin haploinsufficiency on one of the cardinal symptoms of schizophrenia, the impairment of prefrontal-cortex-dependent cognitive function, has yet to be determined...
- Predictors of driving exposure and avoidance in a field study of older drivers from the state of MarylandDavid E Vance
Department of Psychology, Center for Translational Research on Aging and Mobility, University of Alabama at Birmingham, 35294 2100, USA
Accid Anal Prev 38:823-31. 2006..A performance-based assessment, which included the Gross Impairment Screening battery and task 2 of the UFOV test, was completed by participants...
- Multisession, dual-task psychological refractory period practice benefits older and younger adults equallyPhilip A Allen
Department of Psychology, University of Akron, Akron, OH 44325 4301, USA
Exp Aging Res 35:369-99. 2009..Task 1 involved tone discrimination and Task 2 involved simultaneous letter-matching...
- Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zincCatherine E Clarke
Department of Biological Sciences, Imperial College London, Exhibition Road, London SW7 2AZ, UK
J Physiol 560:51-62. 2004..Therefore it is possible that inhibition of IK(SO) in cerebellar granule cells by synaptically released zinc may have important physiological consequences...
- Rhythmic and discrete elements in multi-joint coordinationDagmar Sternad
Department of Kinesiology, The Pennsylvania State University, 266 Rec Hall, University Park, PA 16803, USA
Brain Res 989:152-71. 2003..It was this rhythmic activity that posed the direct constraints on the initiation of the discrete movement...
- The psychological refractory period: evidence for age differences in attentional time-sharingP A Allen
Department of Psychology, Cleveland State University, Ohio 44115, USA
Psychol Aging 13:218-29. 1998..psychological refractory period (PRP) experiments in which the stimulus onset asynchrony (SOA) between Task 1 and Task 2 was 150 ms, 250 ms, 600 ms, and 1,100 ms for both younger and older adults. H...
- High resolution spatiotemporal analysis of the contingent negative variation in simple or complex motor tasks and a non-motor taskR Q Cui
Department of Clinical Neurology, University of Vienna, Wahringer Gurtel 18 20, A 1090, Vienna, Austria
Clin Neurophysiol 111:1847-59. 2000....
- Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transportRichard Warth
Institute of Physiology, Universitatsstrasse 31, 93053 Regensburg, Germany
Proc Natl Acad Sci U S A 101:8215-20. 2004The acid- and volume-sensitive TASK2 K+ channel is strongly expressed in renal proximal tubules and papillary collecting ducts...
- An evaluation of GO annotation retrieval for BioCreAtIvE and GOAEvelyn B Camon
European Molecular Biology Laboratory, European Bionformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
BMC Bioinformatics 6:S17. 2005..BioCreAtIvE task 2 was an experiment to test if automatically derived classification using information retrieval and extraction could ..
- Virtual reality flexible cystoscopy: a validation studyJ Shah
Academic Surgical Unit, Imperial College of Science, Technology and Medicine, St Mary s Hospital, London, UK
BJU Int 90:828-32. 2002..To validate a flexible cystoscopy simulator by determining if it could differentiate between expert and novice cystoscopists...
- pH sensing in the two-pore domain K+ channel, TASK2Michael J Morton
School of Biomedical Sciences, Medical and Dental Building, University of Leeds, Leeds LS2 9NQ, United Kingdom
Proc Natl Acad Sci U S A 102:16102-6. 2005b>TASK2 is a member of the two-pore domain K(+) channel family that plays a role in acid-base homeostasis; TASK2 knockout animals have plasma electrolyte patterns typical of the human clinical condition of renal tubular acidosis...
- Task completion time: Objective tool for assessment of technical skills in laparoscopic simulator for urology traineesShashi K Mishra
Department of Urology and Nephrology, Muljibhai Patel Society for Research in Nephrourology, Muljibhai Patel Urological Hospital, Nadiad 387 001, Gujarat, India
Indian J Urol 24:35-8. 2008..Laparoscopic surgical simulation is a valuable training tool for urology trainees...
- Mining protein function from text using term-based support vector machinesSimon B Rice
Faculty of Life Sciences, University of Manchester, UK
BMC Bioinformatics 6:S22. 2005..We participated in Task 2, which addressed assigning Gene Ontology terms to human proteins and selecting relevant evidence from full-text ..
- Effect of flat insoles with different Shore A values on posture stability in diabetic neuropathyJ A Van Geffen
Center for Rehabilitation, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Prosthet Orthot Int 31:228-35. 2007..It was found that prescribing insoles with a low Shore A value (15 degrees), compared to insoles with a higher Shore A value (30 degrees) has no significant negative effect on posture stability in patients with a diabetic neuropathy...
- The psychological refractory period in Parkinson's diseaseS Hsieh
Department of Psychology, National Chung Cheng University, Taiwan, ROC
Percept Mot Skills 91:893-902. 2000..The stimulus onset asynchrony (SOA) between Task 1 and Task 2 was 50 msec., 150 msec., and 650 msec...
- Effects of selective inhibition of N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasksKrzysztof Lukawski
Department of Pathophysiology, Medical University of Lublin, Jaczewskiego 8, 20 090 Lublin, Poland
Eur J Pharmacol 579:202-7. 2008..In the Y-maze task, MK-801 (0.1 mg/kg i.p.) impaired alternation behavior and considerably increased locomotion in the Y-maze and locomotor activity test. These results indicate that NAALADase inhibition may impair alternation behavior...
- Three-dimensional in vivo quantification of knee kinematics in cerebral palsyFrances T Sheehan
Physical Disabilities Branch, National Institutes of Health, National Institute of Child Health and Human Development and the Clinical Center, National Institutes of Health, Bethesda, MD 20892 1604, USA
Clin Orthop Relat Res 466:450-8. 2008..Fast phase contrast MRI may allow differentiation of patellofemoral and tibiofemoral function in various functional subtypes of cerebral palsy, providing insights into its management...
- Event-related potentials evoked by multi-feature conflict under different attentive conditionsYuping Wang
Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053 PR China
Exp Brain Res 148:451-7. 2003..In task 1, subjects attended to the color of the stimuli and ignored the other attributes. In task 2, they were asked to attend to both color and global shape of stimuli and disregard the local shape...
- Incidental memory of differently processed odorsL Hvastja
Dipartimento di Psicologia Università di Trieste
Percept Mot Skills 85:235-44. 1997..test had to evaluate the intensity of each odor (Task 1), to judge the similarity of each odor to mint (Task 2), or to score each odor for pleasantness and sourness (Task 3)...
- [Analysis of interference effects in simultaneous processing of 2 problems]T Schubert
Institut fur Psychologie, Humboldt Universitat Berlin
Z Exp Psychol 43:625-56. 1996..A well known result is that reaction time on task 2 (Rt2) increases with decreasing overlap of the two tasks...
- Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteriesM J Gardener
School of Biological Sciences, Stopford Building, University of Manchester, Manchester M13 9PT
Br J Pharmacol 142:192-202. 2004....
- Information continuity across the response selection bottleneck: early parallel Task 2 response activation contributes to overt Task 2 performanceSandra J Thomson
Department of Psychology, Neuroscience and Behaviour, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
Atten Percept Psychophys 75:934-53. 2013Several studies of dual-task performance have demonstrated Task 2 to Task 1 response priming (backward compatibility effects), indicating some degree of parallel response computation for concurrent tasks and suggesting that the well-..
- Short and long latency response due to transition from bilateral to unilateral contractionS Safar
Semmelweis University Department of Track and Field Faculty of Physical Education and Sport Sciences Budapest Hungary
Acta Physiol Hung 100:457-68. 2013..In Task 1 subjects exerted bilateral and unilateral torque and bilateral index was calculated. In Task 2 subjects relaxed the right knee extensors as slow as possible while maximum activation of the contralateral muscle ..
- [Occupational ophthalmology and ergoophthalmology: a developing field]B Piccoli
Dipartimento di Medicina del Lavoro Clinica del Lavoro L Devoto, Universita degli Studi di Milano
Med Lav 94:101-7. 2003..of the Milan ICP Hospital, showed that long-term exposure to low levels of irradiation could constitute an eye risk for these working populations...
- TASK-2: a K2P K(+) channel with complex regulation and diverse physiological functionsL Pablo Cid
Centro de Estudios Científicos Valdivia, Chile
Front Physiol 4:198. 2013..Further work in native tissues and cells together with genetic modification will no doubt reveal the details of TASK-2 functions that we are only starting to suspect. ..
- "Crowding" in normal and amblyopic vision assessed with Gaussian and Gabor C'sSrividhya Hariharan
College of Optometry, University of Houston, Houston, TX 77204 6052, USA
Vision Res 45:617-33. 2005..Instead we suggest that crowding in amblyopic and peripheral vision is a result of extended pooling at a stage following the stage of feature detection...
- Midazolam amnesia and short-term/working memory processesJulia Fisher
Department of Psychology, Boston College, USA
Conscious Cogn 15:54-63. 2006..Moreover, they demonstrate that conscious awareness of materials during study is not sufficient to produce episodic memory...
- Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogsChristina T Siwak
Institute of Medical Science, University of Toronto at Scarborough, 1265 Military Trail, Toronto, ON, Canada M1C 1A4
Pharmacol Biochem Behav 76:161-8. 2003..Eighteen aged beagle dogs were tested on a delayed nonmatching-to-position (DNMP) task 2 h following one of three possible treatments; 20 mg/kg of adrafinil, 10 mg/kg of adrafinil or a placebo control...
- Taste receptor cells express pH-sensitive leak K+ channelsW Lin
Cell and Developmental Biology, University of Colorado Health Sciences Center at Fitzsimons, Aurora, Colorado 80045, USA
J Neurophysiol 92:2909-19. 2004..We report here that rat taste receptor cells (TRCs) highly express TASK-2 (KCNK5; K2p5.1), and to a much lesser extent TALK-1 (KCNK16; K2p16.1) and TASK-1 (KCNK3; K2p3...
- Does an abdominal strengthening program influence leg stiffness during hopping tasks?Arnaud Dupeyron
Movement to Health, Montpellier 1 University, Montpellier, France
J Strength Cond Res 27:2129-33. 2013..Our findings suggest the potential role of abdominal muscles in controlling "lumbopelvic" stiffness as a part of the spring according to the spring mass model, and thus influencing kleg by reduced ground contact phase...
- Acid-sensitive two-pore domain potassium (K2P) channels in mouse taste budsTrevor A Richter
Dept of Physiology and Biophysics, University of Miami School of Medicine, 1600 NW 10th Avenue, Miami, FL 33136, USA
J Neurophysiol 92:1928-36. 2004..However, our results do not unambiguously identify any one channel as the acid taste transducer...
- Detecting anomalous features in complex stimuli: the role of structured comparisonKENNETH J KURTZ
Department of Psychology, Binghamton University
J Exp Psychol Appl 19:219-32. 2013..Therefore, task performance in application areas requiring detection of nonobvious anomalies can be improved by providing alignable standards next to targets or in advance training...
- Men's preference for the ovulating female is triggered by subtle face shape differencesCora Bobst
Institute of Psychology, University of Bern, Muesmattstrasse 45, 3012 Bern, Switzerland
Horm Behav 62:413-7. 2012..Thirty-six male participants were asked to choose the more attractive (Task 1), the more caring (Task 2), and the more flirtatious face (Task 3)...
- The countermanding task revisited: fast stimulus detection is a key determinant of psychophysical performanceEmilio Salinas
Department of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1010, USA
J Neurosci 33:5668-85. 2013..The results suggest that manipulations of the countermanding task often cause changes in perceptual detection processes, and not necessarily in inhibition...
- Loss of semantic associative categories in patients with Alzheimer's diseaseDomenico Passafiume
Department of Internal Medicine and Public Health, University of L Aquila, L Aquila, Italy
Appl Neuropsychol Adult 19:305-11. 2012..These data confirm prior research showing the semantic association is differently impaired in AD patients...
- Driver performance while texting: even a little is too muchJoshua D McKeever
Department of Psychology, Drexel University, Philadelphia, PA 19104, USA
Traffic Inj Prev 14:132-7. 2013..To examine the impact of text messaging and other in-car behaviors on driving performance under simple and naturalistic road conditions in a driving simulator...
- Beyond generalized hair cells: molecular cues for hair cell typesIsrat Jahan
University of Iowa, Department of Biology, College of Liberal Arts and Sciences, 143 BB, Iowa City, IA 52242, USA
Hear Res 297:30-41. 2013..Importantly, the molecular means to modify the Atoh1 expression are at least partially understood and can be readily implemented in the attempts to regenerate specific types of HCs...
- Investigation of the role of TASK-2 channels in rat pulmonary arteries; pharmacological and functional studies following RNA interference proceduresMónika Gönczi
Faculty of Life Sciences, University of Manchester, Manchester, M13 PT, UK
Br J Pharmacol 147:496-505. 2006....
- Acoustic cue integration in speech intonation recognition with cochlear implantsShu Chen Peng
Division of Ophthalmic, Neurological, and Ear, Nose and Throat Devices, Office of Device Evaluation, U S Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD 20993, USA
Trends Amplif 16:67-82. 2012..In Task 2, the same listeners' perceptual cue weighting in question-statement identification was assessed using ..
- Expression of K2P channels in sensory and motor neurons of the autonomic nervous systemAlba Cadaveira-Mosquera
Department of Functional Biology, Faculty of Biology, University of Vigo, Campus Lagoas Marcosende, 36310, Vigo, Spain
J Mol Neurosci 48:86-96. 2012..Our results strongly suggest that TRESK and TREK channels are important modulators of the sensorial and motor information flowing through the autonomic nervous system, probably exerting a strong influence on vagal reflexes...
- Demonstrating emotional processing differences in psychopathy using affective ERP modulationNathaniel E Anderson
MIND Research Network, Albuquerque, New Mexico 87131, USA
Psychophysiology 49:792-806. 2012..not task relevant (Task 1) followed by a condition directing attention to the categorization of emotional content (Task 2)...
- An investigation of the effects of relative probability of old and new test items on the neural correlates of successful and unsuccessful source memoryKaia L Vilberg
Center for the Neurobiology of Learning and Memory, and Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 3800, USA
Neuroimage 45:562-71. 2009..They then performed a source memory test with four response options: studied in task 1, studied in task 2, old but unsure of the study task, and new...
- Stability of output effects from motor cortex to forelimb muscles in primatesDarcy M Griffin
Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
J Neurosci 29:1915-27. 2009..This study further validates the use of StTA for mapping and other studies of cortical motor output...
- Bypassing the central bottleneck after single-task practice in the psychological refractory period paradigm: evidence for task automatization and greedy resource recruitmentFrançois Maquestiaux
UFR STAPS de l Université Paris Sud, JE 2494, Batiment 335, 91405 Orsay Cedex, France
Mem Cognit 36:1262-82. 2008..psychological refractory period (PRP) paradigm, in which the highly practiced auditory-vocal task was presented as Task 2, along with an unpracticed visual-manual Task 1...
- Evidence that TASK1 channels contribute to the background current in AH/type II neurons of the guinea-pig intestineH Matsuyama
Department of Anatomy and Cell Biology and Centre for Neuroscience, University of Melbourne, Parkville, Victoria 3010, Australia
Neuroscience 155:738-50. 2008..type II neurons (determined by double labeling for IB4 and NeuN), but no type II neurons were immunoreactive for TASK2 or TASK3. These latter channels were localized to non-type II neurons...
- Upregulated TWIK-related acid-sensitive K+ channel-2 in neurons and perivascular astrocytes in the hippocampus of experimental temporal lobe epilepsyJi Eun Kim
Department of Anatomy and Neurobiology and Institute of Epilepsy Research, College of Medicine, Hallym University, Chunchon, South Korea
Epilepsia 50:654-63. 2009....
- Nonautomatic emotion perception in a dual-task situationDave Tomasik
University of New Mexico, Albuquerque, NM 87131, USA
Psychon Bull Rev 16:282-8. 2009..Task 1 required an auditory discrimination (tone vs. noise), whereas Task 2 required a discrimination between happy and angry faces...
- Does dorsal processing require central capacity? More evidence from the PRP paradigmMarkus Janczyk
Department of Psychology, Dortmund University of Technology, Emil Figge Strasse, Dortmund, Germany
Exp Brain Res 203:89-100. 2010..In particular, response times to task 2 (the grasping task) increased the more the two tasks overlapped in time, i.e...
- Exploring cross-task compatibility in perceiving and producing facial expressions using electromyographyEllen Otte
Institute of Psychology I, RWTH Aachen University, Aachen, Germany
Acta Psychol (Amst) 138:187-92. 2011..In one task, participants were asked to produce a smile or a frown (Task 2) in response to a tone stimulus...
- Modularity beyond perception: evidence from the PRP paradigmHagit Magen
Department of Psychology, Hebrew University, Mt Scopus, Jerusalem, 91905, Israel
J Exp Psychol Hum Percept Perform 36:395-414. 2010..Task 1 in all experiments was a tone discrimination task. In Experiments 1 to 3, Task 2 was a variation of either the Stroop or the flanker tasks...
- Spatial frequency-specific effects on the attentional bias: Evidence for two attentional systemsVaughan V W Singh
Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
Cortex 47:547-56. 2011..Our data are consistent with the idea that the attentional bias results from right-dominant control mechanisms of stimulus-driven attention potentially interacting with voluntary control mechanisms...
- Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behaviorFabrice Jollant
Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
Neuroimage 51:1275-81. 2010..2009). In comparison to affective controls, suicide attempters showed 1) poorer performance on the gambling task 2) decreased activation during risky relative to safe choices in left lateral orbitofrontal and occipital cortices 3)..
- Dual-task interference: the effects of verbal cognitive tasks on upright postural stability in Parkinson's diseaseJ D Holmes
School of Occupational Therapy, The University of Western Ontario, London, ON, Canada N6G 1H1
Parkinsons Dis 2010:696492. 2010..Ironically, this overconstraint may place the participant at greater risk for a fall...
- Under- and over-estimation: a bi-directional mapping process between symbolic and non-symbolic representations of number?Virginie Crollen
Unité de Neurosciences Cognitives NESC, Universite Catholique de Louvain, Belgium
Exp Psychol 58:39-49. 2011..We discussed these empirical data by showing how they can be accounted by the bi-directional mapping hypothesis (Castronovo & Seron, 2007)...
- Blood flow velocity in middle cerebral artery during visuo-motor tasks using a mirror: a transcranial Doppler studyRaphael Bene
University Department of Neurology, Reference Center for Neurovascular Disorders, Ministry of Health and Social Welfare of the Republic of Croatia, Sestre Milosrdnice University Hospital, Zagreb, Croatia
Acta Clin Croat 48:305-10. 2009..than during the illusion of motor hand activation (task 3) and less than during direct vision of hand flexion (task 2, +6.3% baseline value; P = 0.005)...
- Objects and events as determinants of parallel processing in dual tasks: evidence from the backward compatibility effectRavid Ellenbogen
Department of Psychology, Ben Gurion University of the Negev, Beer Sheva, Israel, 84105
J Exp Psychol Hum Percept Perform 37:152-67. 2011..is a major index of parallel processing in dual tasks and is related to the dependency of Task 1 performance on Task 2 response codes (Hommel, 1998)...
- Non-invasive brain stimulation enhances fine motor control of the hemiparetic ankle: implications for rehabilitationSangeetha Madhavan
Department of Physical Therapy, University of Illinois, 1919 W Taylor St, Chicago, IL 60612, USA
Exp Brain Res 209:9-17. 2011..The results provide a basis for examining whether this enhanced ankle control can be induced in patients with greater impairments and whether enhanced control of a single or multiple lower limb joints improves hemiparetic gait patterns...
- Storage and retrieval of addition facts: the role of number comparisonB Butterworth
Department of Psychology, University College London, UK
Q J Exp Psychol A 54:1005-29. 2001..explained by the model; Task 1 was a number naming task to assess the contribution of the pronunciation stage; Task 2 was a magnitude comparison task to assess the contribution, if any, of the comparison stage...
- Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filterLeandro Zúñiga
Centro de Estudios Cientificos, Valdivia, Chile
PLoS ONE 6:e16141. 2011..Our data, therefore, strongly suggest that a cycle of protonation/deprotonation of pH(o)-sensing arginine 224 side chain gates the TASK-2 channel by electrostatically tuning the conformational stability of its selectivity filter...
- Identification and functional characterization of ion channels in CD34(+) hematopoietic stem cells from human peripheral bloodKyoung Sun Park
Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 790 784, Korea
Mol Cells 32:181-8. 2011..3, Kv7.1, Nav1.7, TASK2, TALK2, TWIK2, TRPC4, TRPC6, TRPM2, TRPM7, and TRPV2...
- The architecture of cross-hemispheric communication in the aging brain: linking behavior to functional and structural connectivitySimon W Davis
Center for Cognitive Neuroscience, Duke University, Durham, NC 27708, USA
Cereb Cortex 22:232-42. 2012....
- Neural activation patterns during working memory tasks and OSA disease severity: preliminary findingsKristen H Archbold
University of Arizona College of Nursing, Tucson, AZ, USA
J Clin Sleep Med 5:21-7. 2009..A secondary aim was to explore the possible relation between OSA severity (apnea/hypopnea index) and BOLD-fMRI signal patterns...
- Children's hedonic responses to the odors of alcoholic beverages: a window to emotionsJulie A Mennella
Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
Alcohol 42:249-60. 2008..beer and whiskey in Task 1, and their preference for beer relative to odors that differed in hedonic valence in Task 2. The type of task and behavioral measure revealed different aspects of children's responses, to alcohol odors...
- [Pharmacological studies on Y-8894. (VIII). Effects on learning and memory in the radial maze task in mice]K Anami
Research Laboratories, Yoshitomi Pharmaceutical Industries, Ltd, Fukuoka, Japan
Nihon Yakurigaku Zasshi 92:113-8. 1988..These results suggest that Y-8894 has an ameliorative and/or facilitative effect on learning and memory in the radial maze task, and Y-8894 is more potent than dihydroergotoxine and Ca-hopantenate...
- Activity-dependent modulation of synaptic transmission in the intact human motor cortex revealed with transcranial magnetic stimulationClaudio Bonato
IRCCS Centro S Giovanni di Dio, Fatebenefratelli, Laboratorio di Neurofisiologia, Brescia, Italy
Cereb Cortex 12:1057-62. 2002..Possible anatomo-functional mechanisms involved in this activity-dependent modulation of MI excitability are discussed...
- TASK-1, TASK-2, TASK-3 and TRAAK immunoreactivities in the rat carotid bodyYoshio Yamamoto
Laboratory of Veterinary Anatomy, Faculty of Agriculture, Gifu University, 501 1193, Gifu, Japan
Brain Res 950:304-7. 2002..Our results indicate that TASK-1 immunoreactivity was ubiquitously distributed in many cell types and immunoreactivities for TASK-2, TASK-3 and TRAAK were cell type specific distribution patterns in the rat carotid body...
- Validation of a functional MRI-based reward processing task as a non-invasive tooMARY LOUISE PHILLIPS; Fiscal Year: 2010....
- NEUROPHYSIOLOGICAL & MODELING STUDIES OF LOCUS COERULEUSGary Aston Jones; Fiscal Year: 2000..responsivity to unexpected environmental stimuli. ..
- IMAGING AND MODELING THERAPEUTIC MECHANISMS OF ACTIONPeter Fox; Fiscal Year: 2003....
- A new class of biodegradable synthetic biomaterial for seroma preventionMichael Craven; Fiscal Year: 2012..b>Task 2 - Determine the range of efficacy in vivo using a model involving the harvesting of the rat latissimus dorsi ..
- Development Of An Eye Drop To Treat PresbyopiaWilliam H Garner; Fiscal Year: 2012..If permanent changes in cornea health are observed, lower dose formulations will be prepared and tested;Task 2. Determine the ocular pharmacokinetics of our co-drug, its metabolites, SAM-cycle intermediates and redox balance...
- Engineered Spores as Fluorogenic Biological Indicators for Sterility TestingBoris Rotman; Fiscal Year: 2009..For Task 1, BCR will collaborate with New Horizons Diagnostics Corp. (Columbia, MD). Task 2. To standardize and test the rBI for stability and reproducibility. Task 3...
- Auditory Perception of Drug Names: Neighborhood EffectsBruce Lambert; Fiscal Year: 2006..abstract_text> ..
- Engineered Spores as Fluorogenic Biological Indicators for Sterility TestingBoris Rotman; Fiscal Year: 2007..b>Task 2. Evaluate the biological indicator prototype by comparing it with conventional biological indicators using spore ..
- EVALULATION OF PRENATAL TESTS FOR CHROMOSOMAL DISORDERSA Washington; Fiscal Year: 1993..b>Task 2 will consist of detailed interviews with obstetrical patients undergoing genetic counseling at UCSF to assess ..
- EVALUATOR TRAINING MANIKIN FOR SPASTICITY AND STRENGTHDAVID ENGSBERG; Fiscal Year: 2003..b>Task 2: Test the SSKAT...
- High throughput screening of bacterial collections for surface proteins of commerRoy H Hammerstedt; Fiscal Year: 2010..When successfully implemented, an enhanced method for assessing both new clinical paradigms [such as use of biotherapeutics] as well as improving old analyses [suboptimal diagnostic immunoassays] will be attained. ..
- BEHAVIOR & HORMONE MEDIATION OF HIPPOCAMPAL NEUROGENESISDiane Lee; Fiscal Year: 2001..abstract_text> ..
- Fully Ambulatory Hot Flash Monitoring SystemROBERT LACKEY; Fiscal Year: 2005..b>Task 2 Ambulatory System Performance in Home Setting - This task will characterize the performance of the PhiloMetron ..
- Development of a Miniaturized EMG Telemetry SystemJohn Standeven; Fiscal Year: 2001..A miniature transmitter and receiver from Ramsey Electronics will form the nucleus of this unit. Task 2: Test the single channel EMG unit...
- Radiologists' performance in digital mammography and breast tomosynthesisAndrew D A Maidment; Fiscal Year: 2010..b>Task 2: We will design a graphical user interface for the radiologists to report their decisions after each time-..
- FUNCTIONAL PROPERTIES OF VTA NEURONSAnn Kosobud; Fiscal Year: 2000..The proposed experiments will provide a better understanding of the functional relationship among the various neuron subtypes in the VTA, and the contribution of these neurons to motivated behavior. ..
- Creating Research Files from CMS Data for Integration with Survey DataThomas MaCurdy; Fiscal Year: 2007..MDS and Medicaid); (3) conduct a pilot project demonstrating the effectiveness of the linkage approach created in Task 2; (4) work with CMS and our project survey partners?which include HRS, PSID and NLTCS?to establish protocols that ..
- Transcatheter Intra-arterial Perfusion MRI Monitoring of Liver Tumor EmbolizationANDREW CHRISTIAN LARSON; Fiscal Year: 2010..b>Task 2: To test the hypothesis that TRIP-MRI contrast dose can be optimized intra-procedurally to permit short wash-out ..
- Emotional Reactivity of Intimate Partner AbusersJULIA BABCOCK; Fiscal Year: 2003..abstract_text> ..
- Anti-curli immunotherapy for bacterial pneumoniaKanneganti Murthy; Fiscal Year: 2001..We expect to identify a murine anti-csgA MAb that provides potent protection against E. coli pneumonia induced lethality and pulmonary injury. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
- MARKERS FOR STEM CELL-LIKE COLONIC CRYPT BASE CELLSBruce Boman; Fiscal Year: 2004..AIM 2: To determine gene expression patterns and levels for SCE marker genes in abnormal crypts, (FAP crypts). Task 2: compare gene expression levels and patterns in purified whole crypts from FAP vs...
- EXERCISE OF PATIENTS WITH HEMIPARETIC STROKERichard Macko; Fiscal Year: 2001....
- Affective Dispositions and Attention to Emotion Info.RANDALL LARSEN; Fiscal Year: 2004....
- Glycerol Kinase Deficiency as a Model to Understand Met*Katrina Dipple; Fiscal Year: 2005..transcriptome analysis in the whole animal model using the glycerol kinase knock-out (gyk k/o) mouse (Specific Aim/Task 2)...
- MANAGED CARE, FINANCIAL INCENTIVE & PHYSICIAN PRACTICECarol Simon; Fiscal Year: 2002..b>Task 2: Linked survey of physicians and practices: 2000 physicians and 2000 practice-level decision-makers in 5 states to ..
- Radio Frequency Motion Tracking SystemDAVID ENGSBERG; Fiscal Year: 2003..Virtual movement of the transmitting antenna creates a Doppler shift in the signal at the receiver sensor. Task 2: Evaluation of the 2D device...