Gene Symbol: JPT2
Description: Jupiter microtubule associated homolog 2
Alias: C16orf34, HN1L, L11, jupiter microtubule associated homolog 2, CRAMP_1 like, HN1 like, HN1-like protein, hematological and neurological expressed 1 like, hematological and neurological expressed 1-like protein
Species: human
Products:     JPT2

Top Publications

  1. Carbente R, Maia J, Assef A. Image reconstruction utilizing median filtering applied to elastography. Biomed Eng Online. 2019;18:22 pubmed publisher
    ..The Verasonics Vantage 128 research platform and L11-4v transducer were used to acquire radio frequency signals from a model 049A elastography phantom (CIRS, USA), with ..
  2. Li L, Zheng Y, Jiang C, Fang S, Zeng T, Zhu Y, et al. HN1L-mediated transcriptional axis AP-2γ/METTL13/TCF3-ZEB1 drives tumor growth and metastasis in hepatocellular carcinoma. Cell Death Differ. 2019;: pubmed publisher
    ..Here, we reported a novel potential therapeutic target hematological and neurological expressed 1 like (HN1L) in HCC...
  3. Chen G, Zhu G, Zhang X. [Research progress in PRAS40]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018;43:685-690 pubmed publisher
    ..such as mammalian target of rapamycin complex 1 (mTORC1), protein kinase B (Akt), NF-κB and ribosomal protein L11 (RPL11) etc, which can regulate cell proliferation, senescence, autophagy, apoptosis and exosome secretion...
  4. Hadzik J, Krawiec M, Kubasiewicz Ross P, Prylińska Czyżewska A, Gedrange T, Dominiak M. Short Implants and Conventional Implants in The Residual Maxillary Alveolar Ridge: A 36-Month Follow-Up Observation. Med Sci Monit. 2018;24:5645-5652 pubmed publisher and a minimal width of the alveolar ridge of 6-7 mm: 15 patients received regular dental implants (OsseoSpeed™ L11 Ø4 mm and L13 Ø4 mm) and the implantation was preceded by the sinus lift procedure from a lateral window approach ..
  5. Janockova J, Dolezal R, Nepovimova E, Kobrlova T, Benkova M, Kuca K, et al. Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods. Molecules. 2018;23: pubmed publisher
    ..The presented work is focused on the evaluation of compounds L1L11 selected by structure-based virtual screening for their ability to modulate orexin receptor type 2 (OX2R) in ..
  6. Schiefler N, Maia J, Schneider F, Zimbico A, Assef A, Costa E. Generation and Analysis of Ultrasound Images Using Plane Wave and Sparse Arrays Techniques. Sensors (Basel). 2018;18: pubmed publisher
    ..using simulated echo data (from Field II) and phantom data acquired using a Verasonics system equipped with a L11-4v linear array transducer...
  7. Lee S, Kim J, Kim Y, Seok K, Kim J, Chang Y, et al. Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses. Cell Death Differ. 2012;19:1613-22 pubmed publisher
    ..Recently, it was recognized that nucleolar proteins, including nucleophosmin/B23, ribosomal protein L11, and alternate reading frame (ARF), form the nucleolus-ARF-murine double minute 2 (MDM2) axis in p53 regulatory ..
  8. Maehama T, Kawahara K, Nishio M, Suzuki A, Hanada K. Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 protein. J Biol Chem. 2014;289:20802-12 pubmed
    The nucleolar protein PICT1 regulates tumor suppressor p53 by tethering ribosomal protein L11 within the nucleolus to repress the binding of L11 to the E3 ligase MDM2...
  9. Semanjski M, Germain E, Bratl K, Kiessling A, Gerdes K, Macek B. The kinases HipA and HipA7 phosphorylate different substrate pools in Escherichia coli to promote multidrug tolerance. Sci Signal. 2018;11: pubmed publisher
    ..several additional substrates involved in translation, transcription, and replication, such as ribosomal protein L11 (RplK) and the negative modulator of replication initiation, SeqA...

More Information


  1. Islas Fabila P, Mota Rojas D, Martinez Burnes J, Mora Medina P, Gonzalez Lozano M, Roldan Santiago P, et al. Physiological and metabolic responses in newborn piglets associated with the birth order. Anim Reprod Sci. 2018;197:247-256 pubmed publisher
    ..Groups L1, L2, L11, and L12 had the least score on the vitality scale, the longest expulsion intervals, and longest latency to connect ..
  2. Jiang G, Zhou M, Zhang D, Li X, Liu W. The mechanism of action of a fat regulator: Glycyrrhetinic acid (GA) stimulating fatty acid transmembrane and intracellular transport in blunt snout bream (Megalobrama amblycephala). Comp Biochem Physiol A Mol Integr Physiol. 2018;226:83-90 pubmed publisher
    ..57?g?±?0.98?g) were fed three experimental diets (6% fat/L6 group, control, 11% fat/L11 group, and 11% fat with 0.3?mg?kg-1 GA/L11GA group) for 8?weeks...
  3. Zhou X, Hao Q, Zhang Q, Liao J, Ke J, Liao P, et al. Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibition. Cell Death Differ. 2015;22:755-66 pubmed publisher
    ..These results demonstrate a novel mechanism underlying the inhibition of tumor cell proliferation and growth by these two RPs via TAp73 activation. ..
  4. Delpont N, Escofet I, Pérez Galán P, Spiegl D, Raducan M, Bour C, et al. Modular chiral gold(i) phosphite complexes†Electronic supplementary information (ESI) available: Experimental results and NMR data. CCDC 933751 (L11(AuCl)), 933752 (L12(AuCl)a), 933753 (L9(AuCl)), 933754 (L10(AuCl)), 933756 (L8(AuCl)), 933757 (L12(Au. Catal Sci Technol. 2013;3:3007-3012 pubmed
    ..These chiral gold(i) phosphite complexes are very reactive precatalysts for the [4+2] cycloaddition of aryl-substituted 1,6-enynes with enantiomeric ratios ranging from 86 : 14 up to 94 : 6. ..
  5. Chan K, Kher H, Chang C, Yin W, Tan K. Analysis of Pectate Lyase Genes in Dickeya chrysanthemi Strain L11, Isolated from a Recreational Lake in Malaysia: a Draft Genome Sequence Perspective. Genome Announc. 2015;3: pubmed publisher
    ..D. chrysanthemi strain L11 was discovered in a recreational lake in Malaysia. Here, we present its draft genome sequence.
  6. Kummalue T, Inoue T, Miura Y, Narusawa M, Inoue H, Komatsu N, et al. Ribosomal protein L11- and retinol dehydrogenase 11-induced erythroid proliferation without erythropoietin in UT-7/Epo erythroleukemic cells. Exp Hematol. 2015;43:414-423.e1 pubmed publisher
    ..Lentivirally transduced UT-7/Epo erythroleukemic cells expressing ribosomal protein L11 (RPL11) or retinol dehydrogenase 11 (RDH11) could proliferate in the absence of erythropoietin, and their cell-..
  7. Ray Banerjee S, Pullambhatla M, Foss C, Falk A, Byun Y, Nimmagadda S, et al. Effect of chelators on the pharmacokinetics of (99m)Tc-labeled imaging agents for the prostate-specific membrane antigen (PSMA). J Med Chem. 2013;56:6108-21 pubmed publisher
    ..core (L8-L10), traditional NxSy-based chelating agents with varying charge and polarity for the (99m)Tc-oxo core (L11-L18), and a (99m)Tc-organohydrazine-labeled radioligand (L19)...
  8. Xu L, Shi Y, Liu N, Cai Y. Methyl siloxanes in environmental matrices and human plasma/fat from both general industries and residential areas in China. Sci Total Environ. 2015;505:454-63 pubmed publisher
    ..Calculated fat-plasma partition ratios of methyl siloxanes (D4-D6, L6-L11) in the present study were 5.3-241 mL/g...
  9. Alban C, Tardif M, Mininno M, Brugière S, Gilgen A, Ma S, et al. Uncovering the protein lysine and arginine methylation network in Arabidopsis chloroplasts. PLoS ONE. 2014;9:e95512 pubmed publisher a source of methyltransferases we confirmed the methylation sites of two targets, plastid ribosomal protein L11 and the β-subunit of ATP synthase...
  10. Tran T, Kannan K. Occurrence of cyclic and linear siloxanes in indoor air from Albany, New York, USA, and its implications for inhalation exposure. Sci Total Environ. 2015;511:138-44 pubmed publisher
    ..In this study, five cyclic (D3-D7) and nine linear siloxanes (L3-L11) were determined in 60 indoor air samples collected in Albany, New York, USA...
  11. Bapatu H, Maram R, Murthy R. Robust and Rugged Stability-Indicating HPLC Method for the Determination of Plerixafor and Its Related Impurities in Drug Substances. J Chromatogr Sci. 2015;53:1432-42 pubmed publisher
    ..The method was developed using the Phenomenex Luna L11 column using the gradient program with mobile phase A and mobile phase B, where mobile phase A consists of pH 2...
  12. Zimbico A, Granado D, Schneider F, Maia J, Assef A, Schiefler N, et al. Eigenspace generalized sidelobe canceller combined with SNR dependent coherence factor for plane wave imaging. Biomed Eng Online. 2018;17:109 pubmed publisher
    ..The Field II and the Verasonics ultrasound imaging system with a L11-4v array transducer with a contrast resolution phantom were used to capture the plane wave sequences of simulation ..
  13. Zhang Q, Zhu S, Cheng X, Lu C, Tao W, Zhang Y, et al. Euphorbia factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation in mice through the suppression of NF-κB activation. Biochem Pharmacol. 2018;155:444-454 pubmed publisher
    ..have a long history of usage in Traditional Chinese Medicine. Euphorbia factors L1-L11, extracted from this herb, have been reported to have anti-inflammation and anti-cancer effects...
  14. Gao Y, Selmer M, Dunham C, Weixlbaumer A, Kelley A, Ramakrishnan V. The structure of the ribosome with elongation factor G trapped in the posttranslocational state. Science. 2009;326:694-9 pubmed publisher
    ..interaction of EF-G with ribosomal elements implicated in stimulating catalysis, such as the L10-L12 stalk and the L11 region, and of domain IV of EF-G with the tRNA at the peptidyl-tRNA binding site (P site) and with mRNA shed light ..
  15. Tran T, Abualnaja K, Asimakopoulos A, Covaci A, Gevao B, Johnson Restrepo B, et al. A survey of cyclic and linear siloxanes in indoor dust and their implications for human exposures in twelve countries. Environ Int. 2015;78:39-44 pubmed publisher
    ..highest concentration in dust samples from all countries, except for Japan and South Korea, with a predominance of L11; Kuwait, with L10; and Pakistan and Romania, with L12...
  16. Li S, Yang X, Bao M, Wu Y, Yu W, Han F. Family 13 carbohydrate-binding module of alginate lyase from Agarivorans sp. L11 enhances its catalytic efficiency and thermostability, and alters its substrate preference and product distribution. FEMS Microbiol Lett. 2015;362: pubmed publisher
    ..A new alginate lyase gene, alyL2, was cloned from the marine bacterium Agarivorans sp. L11 by using degenerate and site-finding PCR...
  17. Morikawa M, Yajima H, Nitta R, Inoue S, Ogura T, Sato C, et al. X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding. EMBO J. 2015;34:1270-86 pubmed publisher
    ..KIF5C acquires the 'rigor conformation', where mobile switches I and II are stabilized through L11 and the initial portion of the neck-linker, facilitating effective ADP release and the weak-to-strong transition of ..
  18. López Castilla A, Pons T, Pires J. NMR structure and dynamics of Q4D059, a kinetoplastid-specific and conserved protein from Trypanosoma cruzi. J Struct Biol. 2015;190:11-20 pubmed publisher
    ..Q4D059 adopts a α/β fold that is slightly similar to the ATPase sub-domain IIB of the heat-shock protein 70 (HSP70) and to the N-terminal domain of the ribosomal protein L11.
  19. Slimani A, Hrira M, Najah M, Jomaa W, Maatouk F, Hamda K, et al. PCSK9 polymorphism in a Tunisian cohort: identification of a new allele, L8, and association of allele L10 with reduced coronary heart disease risk. Mol Cell Probes. 2015;29:1-6 pubmed publisher
    ..We investigated the effect of two known alleles for rs72555377, L10 and L11, on the risk of CAD in a Tunisian cohort (218 patients diagnosed by angiography and 125 control subjects)...
  20. Li Y, Challagundla K, Sun X, Zhang Q, Dai M. MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation. Oncotarget. 2015;6:1101-14 pubmed
    ..Yet, mechanism underlying UV-induced c-Myc reduction is not completely understood. Here we report that L11 promotes miR-130a targeting of c-myc mRNA to repress c-Myc expression in response to UV irradiation...
  21. Carr J, Lee H, Jaspers J, Dahlberg A, Jogl G, Gregory S. Phenotypic Suppression of Streptomycin Resistance by Mutations in Multiple Components of the Translation Apparatus. J Bacteriol. 2015;197:2981-8 pubmed publisher
    ..genetic selections and strain constructions, we identified suppressor mutations in EF-Tu or in ribosomal protein L11. Using experimental evolution, we identified amino acid substitutions in EF-Tu or in ribosomal proteins S4, S5, L14,..
  22. Scarabelli G, Soppina V, Yao X, Atherton J, Moores C, Verhey K, et al. Mapping the Processivity Determinants of the Kinesin-3 Motor Domain. Biophys J. 2015;109:1537-40 pubmed publisher
    ..Collectively, our results identify residues in the L8, L11, and α6 regions that contribute to family-specific microtubule interactions and whose mutation affects motor-..
  23. Degiacomi G, Personne Y, Mondésert G, Ge X, Mandava C, Hartkoorn R, et al. Micrococcin P1 - A bactericidal thiopeptide active against Mycobacterium tuberculosis. Tuberculosis (Edinb). 2016;100:95-101 pubmed publisher
    ..We have further identified micrococcin resistant mutations in the ribosomal protein L11 (RplK); the mutations were located in the proline loop at the N-terminus...
  24. Tutuncuoglu B, Jakovljevic J, Wu S, Gao N, Woolford J. The N-terminal extension of yeast ribosomal protein L8 is involved in two major remodeling events during late nuclear stages of 60S ribosomal subunit assembly. RNA. 2016;22:1386-99 pubmed publisher
    ..ITS2 spacer; and reorganization of the central protuberance (CP) containing 5S rRNA and r-proteins L5 (uL18) and L11 (uL5)...
  25. Waku T, Nakajima Y, Yokoyama W, Nomura N, Kako K, Kobayashi A, et al. NML-mediated rRNA base methylation links ribosomal subunit formation to cell proliferation in a p53-dependent manner. J Cell Sci. 2016;129:2382-93 pubmed publisher
    ..Intriguingly, NML depletion increases 60S ribosomal protein L11 (RPL11) levels in the ribosome-free fraction and protein levels of p53 through an RPL11-MDM2 complex, which ..
  26. Demkin V, Koshechkin S, Slesarev A. A novel real-time PCR assay for highly specific detection and quantification of vaginal lactobacilli. Mol Cell Probes. 2017;32:33-39 pubmed publisher
    ..of vaginal lactobacilli allowed us to identify conserved regions in the rplK gene, which encodes ribosomal protein L11, and to design group-specific PCR primers and a probe for selected species from the L...
  27. Li L, Ye T, Gao X, Chen R, Xu J, Xie C, et al. Molecular characterization and functional analysis of the OsPsbR gene family in rice. Mol Genet Genomics. 2017;292:271-281 pubmed publisher
    ..expression levels of three cold stress-induced marker genes were significantly higher in the overexpression lines L11 and L19 in comparison with the wild type...
  28. Gao Y, Li B, Li D, Zhang L. Purification and characteristics of a novel bacteriocin produced by Enterococcus faecalis L11 isolated from Chinese traditional fermented cucumber. Biotechnol Lett. 2016;38:871-6 pubmed publisher
    ..E. faecalis L11 produced a bacteriocin with antimicrobial activity against both Escherichia coli and Staphylococcus aureus...
  29. Zhou W, Bi X, Gao G, Sun L. miRNA-133b and miRNA-135a induce apoptosis via the JAK2/STAT3 signaling pathway in human renal carcinoma cells. Biomed Pharmacother. 2016;84:722-729 pubmed publisher
    ..p-STAT3 and Bcl-2 expression was reduced after miRNA transfection whereas only slight influence on Bcl-2 L11 (BIM) was detected...
  30. Gothelf Y, Kaspi H, Abramov N, Aricha R. miRNA profiling of NurOwn®: mesenchymal stem cells secreting neurotrophic factors. Stem Cell Res Ther. 2017;8:249 pubmed publisher
    ..In an analysis of the miRNA mRNA targets, three mRNA targets of hsa-miR-132-3p (HN-1, RASA1 and KLH-L11) were found to be significantly downregulated...
  31. Jang H, Kim S, Cho Y, Heo K, Lee B, Lee S, et al. GWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy. Epilepsy Res. 2015;115:88-94 pubmed publisher
    ..We found two novel SNPs associated with LTG-induced MPE: rs12668095 near CRAMP1L/TMEM204/IFT140/HN1L (P=4.89×10(-7)) and rs79007183 near TNS3 (P=3...
  32. Agrawal P, Varada R, Sah S, Bhattacharyya S, Varshney U. Species-Specific Interactions of Arr with RplK Mediate Stringent Response in Bacteria. J Bacteriol. 2018;200: pubmed publisher
    ..coli ribosomal protein L11 (a stringent response regulator) is replaced with its homolog from M...
  33. Tadini L, Pesaresi P, Kleine T, Rossi F, Guljamow A, Sommer F, et al. GUN1 Controls Accumulation of the Plastid Ribosomal Protein S1 at the Protein Level and Interacts with Proteins Involved in Plastid Protein Homeostasis. Plant Physiol. 2016;170:1817-30 pubmed publisher
    ..gun1 mutation genetically interacts with mutations of genes for the chloroplast ribosomal proteins S1 (PRPS1) and L11. Analysis of gun1 prps1 lines indicates that GUN1 controls PRPS1 accumulation at the protein level...
  34. Kayama K, Watanabe S, Takafuji T, Tsuji T, Hironaka K, Matsumoto M, et al. GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis. EMBO Rep. 2017;18:123-137 pubmed publisher
    The ribosomal protein L11 (RPL11) binds and inhibits the MDM2 ubiquitin ligase, thereby promoting p53 stability. Thus, RPL11 acts as a tumor suppressor...
  35. Slomnicki L, Hallgren J, Vashishta A, Smith S, Ellis S, Hetman M. Proapoptotic Requirement of Ribosomal Protein L11 in Ribosomal Stress-Challenged Cortical Neurons. Mol Neurobiol. 2018;55:538-553 pubmed publisher
    ..Conversely, knockdown of the RP L11, which in nonneuronal systems mediates p53 activation downstream of ribosomal stress, protected neurons against ..
  36. Huang H, Seeger C, Danielson U, Lindblad P. Analysis of the leakage of gene repression by an artificial TetR-regulated promoter in cyanobacteria. BMC Res Notes. 2015;8:459 pubmed publisher
    ..The L09 promoter was compared to the L10, L11, and L12 promoters that were point-mutated and different in repressed promoter strength...
  37. Mitroshin I, Garber M, Gabdulkhakov A. Crystallographic analysis of archaeal ribosomal protein L11. Acta Crystallogr F Struct Biol Commun. 2015;71:1083-7 pubmed publisher
    Ribosomal protein L11 is an important part of the GTPase-associated centre in ribosomes of all organisms. L11 is a highly conserved two-domain ribosomal protein...
  38. Chiechi A. Normalization of Reverse Phase Protein Microarray Data: Choosing the Best Normalization Analyte. Methods Mol Biol. 2016;1362:77-89 pubmed publisher
    ..ssDNA, glyceraldehyde 3-phosphate dehydrogenase (GAPDH), α/β-tubulin, mitochondrial ribosomal protein L11 (MRPL11), ribosomal protein L13a (RPL13a), β-actin, and total protein) across different sample sets, including ..
  39. Guzik Lendrum S, Rank K, Bensel B, Taylor K, Rayment I, Gilbert S. Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules. Biophys J. 2015;109:1472-82 pubmed publisher
    ..62 μm and exceeding those of KIF3AC and kinesin-1. Loop L11, a component of the microtubule-motor interface and implicated in activating ADP release upon microtubule collision,..
  40. Mazzoleni M, Figuet S, Martin Laffon J, Mininno M, Gilgen A, Leroux M, et al. Dual Targeting of the Protein Methyltransferase PrmA Contributes to Both Chloroplastic and Mitochondrial Ribosomal Protein L11 Methylation in Arabidopsis. Plant Cell Physiol. 2015;56:1697-710 pubmed publisher
    ..The bacterial protein methyltransferase PrmA catalyzes the trimethylation of ribosomal protein L11 (RPL11) at three distinct sites. The role of these modifications is still unknown...
  41. Rau M, Welty R, Tom Stump W, Hall K. Formation of Tertiary Interactions during rRNA GTPase Center Folding. J Mol Biol. 2015;427:2799-815 pubmed publisher
    ..It folds into an intricate tertiary structure upon addition of Mg(2+) ions, which is stabilized by the L11 protein in cocrystal structures...
  42. Chakraborty A, Uechi T, Higa S, Torihara H, Kenmochi N. Loss of ribosomal protein L11 affects zebrafish embryonic development through a p53-dependent apoptotic response. PLoS ONE. 2009;4:e4152 pubmed publisher
    ..b>L11 was recently shown to regulate p53 activity through a direct binding with MDM2 and abrogating the MDM2-induced p53 ..
  43. Yu M, Jia H, Cui F, Yang Y, Zhao Y, Yang M, et al. The Effect of Chinese Herbal Medicine Formula mKG on Allergic Asthma by Regulating Lung and Plasma Metabolic Alternations. Int J Mol Sci. 2017;18: pubmed publisher
    ..Additionally, l-acetylcarnitine (L1), thromboxane B2 (L2), 10-HDoHE (L10), and 5-HETE (L11) were first reported to be potential biomarkers associated with allergic asthma...
  44. Cirigliano A, Rodriguez M, Gagliano M, Bertinetti B, Godeas A, Cabrera G. Liquid chromatography coupled to different atmospheric pressure ionization sources-quadrupole-time-of-flight mass spectrometry and post-column addition of metal salt solutions as a powerful tool for the metabolic profiling of Fusarium oxysporum. J Chromatogr A. 2016;1439:97-111 pubmed publisher
    Fusarium oxysporum L11 is a non-pathogenic soil-borne fungal strain that yielded an extract that showed antifungal activity against phytopathogens...
  45. Hasan I, Madarlis C, Keilig L, DIRK C, Weber A, Bourauel C, et al. Changes in biting forces with implant-supported overdenture in the lower jaw: A comparison between conventional and mini implants in a pilot study. Ann Anat. 2016;208:116-122 pubmed publisher
    ..Ten patients received two to four conventional implants (control group, Ø3.3-3.7mm, L11-13mm) and 16 patients received four to five mini implants (study group, Ø1.8-2...
  46. Salyaev R, Rekoslavskaya N, Stolbikov A, Tret yakova A. Using the omega leader sequence of tobacco mosaic virus to transform tomato fruits with the papillomavirus hpv16 L1 gene to enhance production of the antigenic protein HPV16 L11. Dokl Biochem Biophys. 2016;468:187-9 pubmed publisher
  47. Vasan R, Glazer N, Felix J, Lieb W, Wild P, Felix S, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009;302:168-78 pubmed publisher
    ..Further studies are required to replicate these findings, identify the causal variants at or near these loci, characterize their functional significance, and determine whether they are related to overt cardiovascular disease. ..
  48. Kamina A, Jaremko D, Christen L, Williams N. Essential Assembly Factor Rpf2 Forms Novel Interactions within the 5S RNP in Trypanosoma brucei. mSphere. 2017;2: pubmed publisher
    ..In eukaryotes, the 5S RNP is composed of 5S rRNA, ribosomal proteins L5 and L11, and assembly factors Rpf2 and Rrs1...
  49. Karpova N, Bobinnec Y, Fouix S, Huitorel P, Debec A. Jupiter, a new Drosophila protein associated with microtubules. Cell Motil Cytoskeleton. 2006;63:301-12 pubmed
    ..The jupiter cell lines and fly strain should be of wide interest for biologists interested in in vivo analysis of microtubule dynamics. ..
  50. Liu Y, Choi D, Sheng J, Ensor J, Liang D, Rodriguez Aguayo C, et al. HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway. Stem Cell Reports. 2018;10:212-227 pubmed publisher
    Here, we show that HEMATOLOGICAL AND NEUROLOGICAL EXPRESSED 1-LIKE (HN1L) is a targetable breast cancer stem cell (BCSC) gene that is altered in 25% of whole breast cancer and significantly correlated with shorter overall or relapse-free ..
  51. Chakraborty A, Uechi T, Nakajima Y, Gazda H, O Donohue M, Gleizes P, et al. Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models. Biochem Biophys Res Commun. 2018;495:1839-1845 pubmed publisher
    ..TP53 has been implicated in the pathophysiology of DBA with ribosomal protein (RP) L11 playing a crucial role in the TP53 response...
  52. Jamiolkowski R, Chen C, Cooperman B, Goldman Y. tRNA Fluctuations Observed on Stalled Ribosomes Are Suppressed during Ongoing Protein Synthesis. Biophys J. 2017;113:2326-2335 pubmed publisher
    ..fluorescence resonance energy transfer between adjacent tRNAs and between A-site tRNA and ribosomal protein L11, we found that the tRNAs do not fluctuate between the hybrid and classical states, but instead adopt a position ..
  53. Li L, Zeng T, Zhang B, Li Y, Zhu Y, Guan X. Overexpression of HN1L promotes cell malignant proliferation in non-small cell lung cancer. Cancer Biol Ther. 2017;:1-12 pubmed publisher, we identified and characterized a novel oncogene hematopoietic- and neurologic-expressed sequence 1-like (HN1L) in human NSCLC...
  54. Ashrafzadeh S, Leung D. Novel potato plants with enhanced cadmium resistance and antioxidative defence generated after in vitro cell line selection. PLoS ONE. 2017;12:e0185621 pubmed publisher
    ..Plantlets regenerated from two different lines of Cd-selected calli, L9 and L11, were found to exhibit enhanced resistance to 218 ?M Cd compared to control (source plantlets for leaf explants ..
  55. Yang M, Zhang Y, Zhang H, Wang H, Wei T, Che S, et al. Identification of MsHsp20 Gene Family in Malus sieversii and Functional Characterization of MsHsp16.9 in Heat Tolerance. Front Plant Sci. 2017;8:1761 pubmed publisher
    ..9-L11. However, MsHsp16.9 could activate ABA-dependent signaling pathways in all transgenic plants...
  56. Guzik Lendrum S, Rayment I, Gilbert S. Homodimeric Kinesin-2 KIF3CC Promotes Microtubule Dynamics. Biophys J. 2017;113:1845-1857 pubmed publisher
    ..of KIF3CC were not shared by heterodimeric KIF3AC and required the unique KIF3C-specific sequence extension in loop L11 at the microtubule interface...
  57. Pereira N, do Carmo A, Campos K, Costa S, Diniz M, Gomez R, et al. DNA methylation polymerase chain reaction (PCR) array of apoptosis-related genes in pleomorphic adenomas of the salivary glands. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;124:554-560 pubmed publisher
    ..TNFRSF25 and BCL2 L11 were highly methylated in PAs, in comparison with NSGs, irrespective of tumor size...
  58. Carlston C, Afify Z, Palumbos J, Bagley H, Barbagelata C, Wooderchak Donahue W, et al. Variable expressivity and incomplete penetrance in a large family with non-classical Diamond-Blackfan anemia associated with ribosomal protein L11 splicing variant. Am J Med Genet A. 2017;173:2622-2627 pubmed publisher
    ..Diamond-Blackfan anemia-7 (DBA7), caused by heterozygous mutations in ribosomal protein L11 (RPL11), accounts for approximately 5% of DBA...
  59. Tsoi H, Lam K, Dong Y, Zhang X, Lee C, Zhang J, et al. Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients. Oncogene. 2017;36:6109-6118 pubmed publisher
    ..G1/S cell-cycle transition by stabilizing p53 through inducing murine double minute 2 (MDM2) and ribosomal protein L11 (RpL11) interaction...
  60. Petroziello J, Yamane A, Westendorf L, Thompson M, McDonagh C, Cerveny C, et al. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. Oncogene. 2004;23:7734-45 pubmed
  61. Zhou G, Wang J, Zhang Y, Zhong C, Ni J, Wang L, et al. Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family. Gene. 2004;331:115-23 pubmed publisher
    ..cloning and characterization of two novel human genes--HN1 (hematopoietic- and neurologic-expressed sequence 1) and HN1L (HN1-like gene) which are proposed to be involved in embryo development. HN1 is mapped on chromosome 17q25...
  62. Yang H, Noel J, Whitford P. Anisotropic Fluctuations in the Ribosome Determine tRNA Kinetics. J Phys Chem B. 2017;121:10593-10601 pubmed publisher
    ..In addition to rearrangements in the aa-tRNA molecule, the L11 stalk can undergo large-scale anisotropic motions during translation...