HSD11B1L

Summary

Gene Symbol: HSD11B1L
Description: hydroxysteroid (11-beta) dehydrogenase 1-like
Alias: 11-DH3, 11-beta-HSD3, HSD3, SCDR10, SCDR10B, SDR26C2, 11-beta-hydroxysteroid dehydrogenase type 3, hydroxysteroid 11-beta-dehydrogenase 1-like protein, short chain dehydrogenase/reductase 10, short chain dehydrogenase/reductase family 26C, member 2
Species: human

Top Publications

  1. doi Evolution of 11beta-hydroxysteroid dehydrogenase-type 1 and 11beta-hydroxysteroid dehydrogenase-type 3
    Michael E Baker
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093 0693, USA
    FEBS Lett 584:2279-84. 2010
  2. doi Evidence for expression of 11β-hydroxysteroid dehydrogenase type3 (HSD11B3/HSD11B1L) in neonatal pig testis
    Shuji Ohno
    Department of Biochemistry, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan
    Mol Cell Biochem 381:145-56. 2013
  3. ncbi Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics
    Charles R Kissinger
    Pfizer La Jolla, 10777 Science Center Dr, San Diego, CA 92121, USA
    J Mol Biol 342:943-52. 2004
  4. ncbi Isolation and characterization of novel human short-chain dehydrogenase/reductase SCDR10B which is highly expressed in the brain and acts as hydroxysteroid dehydrogenase
    Chaoqun Huang
    State Key Laboratory of Genetic Engineering, The Institute of Genetics, Fudan University, Shanghai, People s Republic of China
    Acta Biochim Pol 56:279-89. 2009

Scientific Experts

  • Michael E Baker
  • Shuji Ohno
  • Chaoqun Huang
  • Charles R Kissinger
  • Saiyin Hexige
  • Long Yu
  • Bo Wan
  • Bo Gao
  • Richard E Showalter
  • Anna Tempczyk-Russell
  • Charles S Agree
  • Melwyn A Abreo
  • James A Thomson
  • Darin Vanderpool
  • Bin Li
  • Stephen Margosiak
  • Jerry J Meng
  • Paul A Rejto
  • J Ernest Villafranca
  • Robert M Aust
  • Laura A Pelletier

Detail Information

Publications4

  1. doi Evolution of 11beta-hydroxysteroid dehydrogenase-type 1 and 11beta-hydroxysteroid dehydrogenase-type 3
    Michael E Baker
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093 0693, USA
    FEBS Lett 584:2279-84. 2010
    ..11beta-HSD1 is a paralog of 11beta-HSD3, whose physiological function remains unclear...
  2. doi Evidence for expression of 11β-hydroxysteroid dehydrogenase type3 (HSD11B3/HSD11B1L) in neonatal pig testis
    Shuji Ohno
    Department of Biochemistry, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan
    Mol Cell Biochem 381:145-56. 2013
    ..A third HSD11B isozyme, HSD11B1L (SCDR10b), has recently been identified...
  3. ncbi Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics
    Charles R Kissinger
    Pfizer La Jolla, 10777 Science Center Dr, San Diego, CA 92121, USA
    J Mol Biol 342:943-52. 2004
    ..The crystal structure provides a basis for the design of potent, highly specific ABAD/HSD10 inhibitors with potential application in the treatment of Alzheimer's disease...
  4. ncbi Isolation and characterization of novel human short-chain dehydrogenase/reductase SCDR10B which is highly expressed in the brain and acts as hydroxysteroid dehydrogenase
    Chaoqun Huang
    State Key Laboratory of Genetic Engineering, The Institute of Genetics, Fudan University, Shanghai, People s Republic of China
    Acta Biochim Pol 56:279-89. 2009
    ..We report here the cloning and characterization of a novel human SDR gene SCDR10B which encodes a protein with similarity to 11beta-hydroxysteroid dehydrogenase 1...