Gene Symbol: HIST1H2AG
Description: histone cluster 1 H2A family member g
Alias: H2A.1b, H2A/p, H2AFP, H2AG, pH2A/f, histone H2A type 1, H2A histone family, member P, H2A.1, histone 1, H2ag, histone H2A/p, histone H2A/ptl, histone cluster 1, H2ag
Mannironi C, Orr A, Hatch C, Pilch D, Ivanova V, Bonner W. The relative expression of human histone H2A genes is similar in different types of proliferating cells. DNA Cell Biol. 1994;13:161-70 pubmed
..These findings suggest that the relative expression of the individual members of a histone gene family is independent of the type of replicating cell. ..
Boyne M, Pesavento J, Mizzen C, Kelleher N. Precise characterization of human histones in the H2A gene family by top down mass spectrometry. J Proteome Res. 2006;5:248-53 pubmed
..This unequivocal identification of H2A forms illustrates the advantages of Top Down Mass Spectrometry and provides a global perspective of H2A regulation through the cell cycle. ..
Albig W, Trappe R, Kardalinou E, Eick S, Doenecke D. The human H2A and H2B histone gene complement. Biol Chem. 1999;380:7-18 pubmed
..The genes show varying expression patterns in different tumor cell lines. ..
Ahn J, Gruen J. The genomic organization of the histone clusters on human 6p21.3. Mamm Genome. 1999;10:768-70 pubmed
Weinmann A, Yan P, Oberley M, Huang T, Farnham P. Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev. 2002;16:235-44 pubmed
..We suggest that human CpG microarrays, in combination with chromatin immunoprecipitation, will allow rapid identification of target promoters for many mammalian transcription factors. ..
Nicassio F, Corrado N, Vissers J, Areces L, Bergink S, Marteijn J, et al
. Human USP3 is a chromatin modifier required for S phase progression and genome stability. Curr Biol. 2007;17:1972-7 pubmed
..Together, our results implicate USP3 as a novel chromatin modifier in the maintenance of genome integrity. ..
Richly H, Rocha Viegas L, Ribeiro J, Demajo S, Gundem G, Lopez Bigas N, et al
. Transcriptional activation of polycomb-repressed genes by ZRF1. Nature. 2010;468:1124-8 pubmed publisher
..We provide here a model of the molecular mechanism of switching polycomb-repressed genes to an active state. ..
Soldi M, Bonaldi T. The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components. Mol Cell Proteomics. 2013;12:764-80 pubmed publisher
..X and WICH, both enriched in silent domains. Chromatin proteomics expands the arsenal of tools for deciphering how all the distinct protein components act together to enforce a given region-specific chromatin status. ..
Lubula M, Eckenroth B, Carlson S, Poplawski A, Chruszcz M, Glass K. Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain. FEBS Lett. 2014;588:3844-54 pubmed publisher
..Our results provide critical insights into the molecular mechanism of ligand binding by the BRPF1 bromodomain, and reveal that ordered water molecules are an essential component driving ligand recognition. ..