HELT

Summary

Gene Symbol: HELT
Description: helt bHLH transcription factor
Alias: HCM1228, HESL, Mgn, bHLHb44, hairy and enhancer of split-related protein HELT, HES/HEY-like transcription factor, Hes-like transcription factor, Hey-like transcription factor, Hey-like transcriptional repressor, Megane bHLH factor
Species: human
Products:     HELT

Top Publications

  1. Lin W, Metzakopian E, Mavromatakis Y, Gao N, Balaskas N, Sasaki H, et al. Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development. Dev Biol. 2009;333:386-96 pubmed publisher
    ..Foxa1 and Foxa2 also inhibit GABAergic neuron differentiation by repressing the Helt gene in the ventral midbrain...
  2. Astals S, Peces M, Batstone D, Jensen P, Tait S. Characterising and modelling free ammonia and ammonium inhibition in anaerobic systems. Water Res. 2018;143:127-135 pubmed publisher
    ..Finally, experimental and model results show that at pH 7.3-7.7 and TAN concentrations above 2000 mgN·L-1, both NH3 and NH4+ contribute significantly to overall inhibition.
  3. Alsayed A, Fergala A, Eldyasti A. Enhancement of the cultivation process conditions of mixed culture methanotrophic Proteobacteria phylum enriched from waste activated sludge as the first step for value added recovery process. J Biosci Bioeng. 2019;127:602-608 pubmed publisher
    ..Thereafter, the specific nitrate uptake rate has been determined to be ranging from 0.05 to 0.62 mgN-NO3/mgTSS/day based on the cultures OD600...
  4. Kalbermatter S, Marone C, Casartelli D, Hausberg M, Banfi G, Mihatsch M, et al. Outcome of fibrillary glomerulonephritis. Swiss Med Wkly. 2012;142:w13578 pubmed publisher
    ..In relation to the histological pattern membranous glomerulonephritis (MGN) had a better outcome as compared to the other histological patterns...
  5. Onodera T, Okubo T, Uemura S, Yamaguchi T, Ohashi A, Harada H. Long-term performance evaluation of down-flow hanging sponge reactor regarding nitrification in a full-scale experiment in India. Bioresour Technol. 2016;204:177-184 pubmed publisher
    ..2) dense retained sludge in the range of 23-46 gVSS Lsponge(-1), and (3) adequate sludge activity of 52 mgN gVSS(-1) day(-1) for nitrification...
  6. Makhdoomi K, Abkhiz S, Noroozinia F, Mivefroshan A, Zeinali J, Jafari L, et al. Recurrent idiopathic membranous glomerulonephritis after kidney transplantation and successful treatment with rituximab. Iran J Kidney Dis. 2015;9:158-62 pubmed
    After renal transplantation approximately forty percent of patients with membranous glomerolunephritis (MGN) had a recurrence, most commonly during the first year...
  7. Zhang L, Duan H, Ye L, Liu L, Batstone D, Yuan Z. Increasing capacity of an anaerobic sludge digester through FNA pre-treatment of thickened waste activated sludge. Water Res. 2019;149:406-413 pubmed publisher
    ..With 24 h pre-treatment of TWAS at an FNA concentration of 6.1 mgN/L (NO2-N = 250 mg/L, pH = 5...
  8. He C, Zou Z, Xia S, Xing X, Hu S, Hu Z, et al. Application of highly efficient and lowly toxic bufadienolides screened from toad skin in lymphatic chemotherapy for colorectal cancer through a lymphatic metastatic model. Int Immunopharmacol. 2019;70:241-251 pubmed publisher
    ..However, effects of the highly efficient and lowly toxic (HELT) bufadienolides on CRC in lymphatic chemotherapy have not been reported...
  9. Stahl R, Hoxha E. [Membranous glomerulonephritis : An example of individualized medicine in nephrology]. Internist (Berl). 2019;: pubmed publisher
    Membranous glomerulonephritis (MGN) is the most frequent cause of a nephrotic syndrome in adults. It is an autoimmune disease caused by binding of autoantibodies to endogenous proteins expressed on glomerular podocytes...

More Information

Publications111 found, 100 shown here

  1. Petrini S, Foladori P, Andreottola G. Laboratory-scale investigation on the role of microalgae towards a sustainable treatment of real municipal wastewater. Water Sci Technol. 2018;78:1726-1732 pubmed publisher
    ..The ammonium removal rate was 2.9 mgN L-1 h-1, which corresponded to 2.4 mgN gTSS-1 h-1...
  2. Rich M, Huang Y, Torregrossa M. Plasticity at Thalamo-amygdala Synapses Regulates Cocaine-Cue Memory Formation and Extinction. Cell Rep. 2019;26:1010-1020.e5 pubmed publisher
    ..strength of the drug cue association corresponds to the strength of synapses between the medial geniculate nucleus (MGN) of the thalamus and the lateral amygdala (LA)...
  3. Meng D, Chen H, Lin Y, Lin H, Hou C. Transferring of femoral nerve motor branches for high-level sciatic nerve injury: a cadaver feasibility study. Acta Neurochir (Wien). 2019;161:279-286 pubmed publisher
    ..nerve (SAN)) and respective recipient nerves (deep peroneal nerve branch (DPN), medial gastrocnemius nerve branch (MGN), sural nerve (SN)) were conducted in six fresh-frozen lower limbs...
  4. Gupta T, Marlow F, Ferriola D, Mackiewicz K, Dapprich J, Monos D, et al. Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte. PLoS Genet. 2010;6:e1001073 pubmed publisher
    ..We report the identification of the zebrafish magellan (mgn) mutant, which exhibits a novel enlarged Balbiani body phenotype and a disruption of oocyte polarity...
  5. Gray D, Rudolph M, Engle J, Recanzone G. Parvalbumin increases in the medial and lateral geniculate nuclei of aged rhesus macaques. Front Aging Neurosci. 2013;5:69 pubmed publisher
    ..whether these increases occur in the thalamic division of the auditory system, the medial geniculate nucleus (MGN)...
  6. Nguyen T, Némery J, Gratiot N, Strady E, Tran V, Nguyen A, et al. Nutrient dynamics and eutrophication assessment in the tropical river system of Saigon - Dongnai (southern Vietnam). Sci Total Environ. 2019;653:370-383 pubmed publisher
    ..7 ± 0.6 mgN L-1 and 0.07 ± 0...
  7. Watanabe M, Miura S, Hasegawa S, Koshikawa M, Takamatsu T, Kohzu A, et al. Coniferous coverage as well as catchment steepness influences local stream nitrate concentrations within a nitrogen-saturated forest in central Japan. Sci Total Environ. 2018;636:539-546 pubmed publisher
    ..Although stream nitrate concentrations varied from 0.5 to 3.0?mgN?L-1, those in 31 catchments consistently exceeded 1?mgN?L-1, indicating that this forest had ..
  8. Nyangahu D, Lennard K, Brown B, Darby M, Wendoh J, Havyarimana E, et al. Disruption of maternal gut microbiota during gestation alters offspring microbiota and immunity. Microbiome. 2018;6:124 pubmed publisher
    ..5 days prior to delivery (gestation; Mg), 14 days postpartum during nursing (Mn), or during gestation and nursing (Mgn), or no vancomycin (Mc)...
  9. Qiao L, Xu W, Mao S, Li Y, Zhang Y. Study on the expanded culture and kinetics of anammox bacteria in the upper flow packed bed. Sci Total Environ. 2019;650:1173-1181 pubmed publisher
    ..The Monod model showed that the theoretical maximum total nitrogen removal concentration was near 1700 mgN/(gVSS·d)...
  10. Pérez Martínez A, Valentín J, Fernández L, Hernández Jiménez E, López Collazo E, Zerbes P, et al. Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell-mediated cytotoxicity against neuroblastoma in vitro and in vivo. Cytotherapy. 2015;17:601-12 pubmed publisher
    ..NK cells are emerging as a tool for adoptive cancer immunotherapies. Arabinoxylan rice bran (MGN-3/Biobran) has been described as a biological response modifier that can enhance the cytotoxic activity of NK cells...
  11. Wei S, Li D, Liu Z, Li X, Tian F, Duan D, et al. Alkaline-earth metal (Mg) polynitrides at high pressure as possible high-energy materials. Phys Chem Chem Phys. 2017;19:9246-9252 pubmed publisher
    ..Using the unbiased structure searching method, five stable chemical stoichiometries of magnesium polynitrides (MgN, Mg2N3, MgN2, MgN3, and MgN4) were theoretically predicted ..
  12. Li W, Shan X, Wang Z, Lin X, Li C, Cai C, et al. Effect of self-alkalization on nitrite accumulation in a high-rate denitrification system: Performance, microflora and enzymatic activities. Water Res. 2016;88:758-765 pubmed publisher
    ..20 and caused a tremendous accumulation of nitrite up to 451.1 ± 49.0 mgN L(-1) at nitrate loading rate (NLR) from 35 kgN m(-3) d(-1) to 55 kgN m(-3) d(-1)...
  13. Foladori P, Petrini S, Nessenzia M, Andreottola G. Enhanced nitrogen removal and energy saving in a microalgal-bacterial consortium treating real municipal wastewater. Water Sci Technol. 2018;78:174-182 pubmed publisher
    ..In particular, the nitrification rate was 1.9 mgN L-1 h-1 (specific rate 2...
  14. Kumari V, Fannon D, ffytche D, Raveendran V, Antonova E, Premkumar P, et al. Functional MRI of verbal self-monitoring in schizophrenia: performance and illness-specific effects. Schizophr Bull. 2010;36:740-55 pubmed publisher
    ..Our results revealed activation of the thalamus (medial geniculate nucleus, MGN) and frontotemporal regions with accurate monitoring across all participants...
  15. Zhang H, Du R, Cao S, Wang S, Peng Y. Mechanisms and characteristics of biofilm formation via novel DEAMOX system based on sequencing biofilm batch reactor. J Biosci Bioeng. 2019;127:206-212 pubmed publisher
    ..29 mgN gVSS-1h-1, which were significantly higher than in suspended sludge (2...
  16. Chang C, Grace A. Dopaminergic Modulation of Lateral Amygdala Neuronal Activity: Differential D1 and D2 Receptor Effects on Thalamic and Cortical Afferent Inputs. Int J Neuropsychopharmacol. 2015;18: pubmed publisher
    ..the lateral nucleus of the amygdala (LA) integrates a conditioned stimulus (CS) from the auditory thalamus (MGN) and the auditory association cortex (Te3) with an aversive unconditioned stimulus...
  17. Beversdorf L, Rude K, Weirich C, Bartlett S, Seaman M, Kozik C, et al. Analysis of cyanobacterial metabolites in surface and raw drinking waters reveals more than microcystin. Water Res. 2018;140:280-290 pubmed publisher
    ..TBPs) that have gained less attention including cyanopeptolins (Cpts), anabaenopeptins (Apts), and microginins (Mgn)...
  18. Liu B, Terashima M, Quan N, Ha N, Van Chieu L, Goel R, et al. High nitrite concentration accelerates nitrite oxidising organism's death. Water Sci Technol. 2018;77:2812-2822 pubmed publisher
    ..demonstrated that these measureable parameters were all decayed when nitrite concentration exceeded 100-500 mgN/L at pH 7.0 in the system, indicating that nitrite poisoning took place...
  19. Gai X, Jiang Z, Liu M, Li Q, Wang S, Li T, et al. Therapeutic Effect of a Novel Nano-Drug Delivery System on Membranous Glomerulonephritis Rat Model Induced by Cationic Bovine Serum. AAPS PharmSciTech. 2018;19:2195-2202 pubmed publisher
    In order to explore a novel high efficacy drug delivery system for membranous glomerulonephritis (MGN), a complex chronic inflammation, methylprednisolone bovine serum albumin nanoparticles (ME BSA NPs) were designed...
  20. Zhang C, Leng L, Zhang X, Zhao Y, Li Z. Comprehensive identification of immune-associated biomarkers based on network and mRNA expression patterns in membranous glomerulonephritis. J Transl Med. 2018;16:210 pubmed publisher
    Membranous glomerulonephritis (MGN) is the most common cause of nephrotic syndrome in adult patients...
  21. Nie X, Xu Y, Song Z, Ding D, Gao F, Liang H, et al. Magnetic-graphitic-nanocapsule templated diacetylene assembly and photopolymerization for sensing and multicoded anti-counterfeiting. Nanoscale. 2014;6:13097-103 pubmed publisher
    ..Here we report a multifunctional, self-assembled system based on magnetic-graphitic-nanocapsule (MGN) templated diacetylene assembly and photopolymerization...
  22. Yang D, Zou R, Zhu Y, Liu B, Yao D, Jiang J, et al. Magainin II modified polydiacetylene micelles for cancer therapy. Nanoscale. 2014;6:14772-83 pubmed publisher
    ..In this study, we developed an effective strategy to directly conjugate magainin II (MGN-II) to the surface of PDA micelles using a fluorescent dye...
  23. Truong D, Rendall A, Rosen G, Fitch R. Morphometric changes in subcortical structures of the central auditory pathway in mice with bilateral nodular heterotopia. Behav Brain Res. 2015;282:61-9 pubmed publisher
    ..of reading disability show morphological changes in the auditory thalamic nucleus (medial geniculate nucleus; MGN) and auditory processing impairments, thus suggesting a link between MCD, MGN, and auditory processing behavior...
  24. Liman A, Dalin P, Björkman C. Enhanced leaf nitrogen status stabilizes omnivore population density. Oecologia. 2017;183:57-65 pubmed publisher
    ..density and a 63 % decrease in population variability with an increase in leaf nitrogen status from 26 to 40 mgN × g-1...
  25. Bolz S, Totzeck A, Amann K, Stettner M, Kleinschnitz C, Hagenacker T. CIDP, myasthenia gravis, and membranous glomerulonephritis - three autoimmune disorders in one patient: a case report. BMC Neurol. 2018;18:113 pubmed publisher
    ..demyelinating polyneuropathy (CIDP), antibody-positive myasthenia gravis (MG), and membranous glomerulonephritis (MGN) confirmed by biopsy...
  26. Abu Elmagd M, Goljanek Whysall K, Wheeler G, Münsterberg A. Sprouty2 mediated tuning of signalling is essential for somite myogenesis. BMC Med Genomics. 2015;8 Suppl 1:S8 pubmed publisher
    ..we analysed chick Spry2 expression and showed that it overlaps with that of myogenic regulatory factors MyoD and Mgn. Targeted mis-expression of Spry2 led to inhibition of myogenesis, whilst its C-terminal domain led to an increased ..
  27. Mannina G, Ekama G, Capodici M, Cosenza A, Di Trapani D, Ødegaard H. Integrated fixed-film activated sludge membrane bioreactors versus membrane bioreactors for nutrient removal: A comprehensive comparison. J Environ Manage. 2018;226:347-357 pubmed publisher
    ..The short-term effect of the inlet C/N ratio variation (C/N = 5 mgCOD/mgN and C/N = 10 mgCOD/mgN) on the behaviour of both plants was investigated...
  28. Dai X, Yan H, Li N, He J, Ding Y, Dai L, et al. Metabolic adaptation of microbial communities to ammonium stress in a high solid anaerobic digester with dewatered sludge. Sci Rep. 2016;6:28193 pubmed publisher
    ..3?±?1.5% in the last period (day 71-110) when ammonium concentration was elevated to be within 5,000-6,000?mgN/L. Biogas yield dropped accordingly from 11.9?±?0.3 to 10.4?±?0...
  29. Duan H, Wang Q, Erler D, Ye L, Yuan Z. Effects of free nitrous acid treatment conditions on the nitrite pathway performance in mainstream wastewater treatment. Sci Total Environ. 2018;644:360-370 pubmed publisher
    ..22, 0.31 and 0.38, respectively), two FNA concentrations (1.35?mgN/L and 4...
  30. Raimonet M, Vilmin L, Flipo N, Rocher V, Laverman A. Modelling the fate of nitrite in an urbanized river using experimentally obtained nitrifier growth parameters. Water Res. 2015;73:373-87 pubmed publisher
    ..The sediment layer constituted a significant source of nitrite, especially during high river discharges (0.1-0.4 mgN h(-1) m(-2))...
  31. Serghiou G, Ji G, Odling N, Reichmann H, Morniroli J, Boehler R, et al. Creating Reactivity with Unstable Endmembers using Pressure and Temperature: Synthesis of Bulk Cubic Mg0.4 Fe0.6 N. Angew Chem Int Ed Engl. 2015;54:15109-12 pubmed publisher
    ..This is a system where, neither an alloy nor a nitride solid solution form at ambient conditions and bulk MgN and FeN endmembers do not form, either at ambient or at high pressure...
  32. Ooi S, McMullen D, Golombick T, Nut D, Pak S. Evidence-Based Review of BioBran/MGN-3 Arabinoxylan Compound as a Complementary Therapy for Conventional Cancer Treatment. Integr Cancer Ther. 2017;:1534735417735379 pubmed publisher
    ..BioBran/MGN-3 Arabinoxylan is a standardized arabinoxylan concentrate which has been proposed as a plant-based immunomodulator ..
  33. Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, et al. Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015;398:280-91 pubmed publisher
    ..Here, we show that a combinatorial interaction between the bHLH transcription factors Ascl1 and Helt is required for acquiring thalamic progenitor identity...
  34. Wang K, Yin W, Tan F, Wu D. Efficient Utilization of Waste Carbon Source for Advanced Nitrogen Removal of Landfill Leachate. Biomed Res Int. 2017;2017:2057035 pubmed publisher
    ..Also, the specific nitrogen removal rate was 1.48?mgN/(h·gvss)...
  35. Kizito S, Wu S, Kipkemoi Kirui W, Lei M, Lu Q, Bah H, et al. Evaluation of slow pyrolyzed wood and rice husks biochar for adsorption of ammonium nitrogen from piggery manure anaerobic digestate slurry. Sci Total Environ. 2015;505:102-12 pubmed publisher
    ..The maximum NH4(+)-N adsorption from slurry at 1400 mgN·L(-1) was 44.64 ± 0.602 mg·g(-1) and 39.8 ± 0...
  36. Keifer O, Gutman D, Hecht E, Keilholz S, Ressler K. A comparative analysis of mouse and human medial geniculate nucleus connectivity: a DTI and anterograde tracing study. Neuroimage. 2015;105:53-66 pubmed publisher
    ..The medial geniculate nucleus (MGN) has been studied mostly in the context of auditory processing and its connection to the auditory cortex...
  37. Insel G, Karagunduz A, Aksel M, Çokgör E, Kor Bicakci G, Ozyildiz G, et al. Membrane integrated process for advanced treatment of high strength Opium Alkaloid wastewaters. Water Sci Technol. 2018;77:1899-1908 pubmed publisher
    ..The MBR system provided complete removal of total inorganic nitrogen; however, nearly 50 mgN/L organic nitrogen remained in the permeate...
  38. González Camejo J, Barat R, Ruano M, Seco A, Ferrer J. Outdoor flat-panel membrane photobioreactor to treat the effluent of an anaerobic membrane bioreactor. Influence of operating, design, and environmental conditions. Water Sci Technol. 2018;78:195-206 pubmed publisher
    ..Maximum nitrogen and phosphorus removal rates of 12.5 ± 4.2 mgN·L-1·d-1 and 1.5 ± 0...
  39. Cakir U, Kirimlioglu H, Basdemir G. Kidney biopsy reveals metastatic adenocarcinoma of the appendix simulating nephrotic syndrome. Eur Rev Med Pharmacol Sci. 2014;18:2424-7 pubmed
    Membranous glomerulonephritis (MGN) is among the most common causes of nephrotic syndrome in adults. The malignancy in presumed tumor-induced MGN has usually been diagnosed at the time the proteinuria is discovered...
  40. Han Y, Li P, Xu Y, Li H, Song Z, Nie Z, et al. Fluorescent nanosensor for probing histone acetyltransferase activity based on acetylation protection and magnetic graphitic nanocapsules. Small. 2015;11:877-85 pubmed publisher
    ..Four kinds of nano-quenchers, including core-shell magnetic graphitic nanocapsules (MGN), graphene oxide (GO), single-walled carbon nanotubes (SWCNTs), and gold nanoparticles (AuNPs), are comprehensively ..
  41. Shen Y, Ma Z, Chen F, Dong Q, Hu Q, Bai L, et al. Effective photothermal chemotherapy with docetaxel-loaded gold nanospheres in advanced prostate cancer. J Drug Target. 2015;23:568-76 pubmed publisher
    Multifunctional gold nanospheres (MGNs)-loaded with docetaxel (MGN@DTX) were prepared and evaluated for therapeutic efficacy in nude mice bearing human prostate cancer xenografts...
  42. Guimera J, Vogt Weisenhorn D, Echevarria D, Martinez S, Wurst W. Molecular characterization, structure and developmental expression of Megane bHLH factor. Gene. 2006;377:65-76 pubmed
    ..analysis relevant to morphological marker genes and mapping of a bHLH transcription gene, referred to as Megane (Mgn). Mgn protein is structurally related to the neurogenic Drosophila hairy and Enhancer of split (h/E(spl)) proteins...
  43. Wende C, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, et al. Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis. PLoS ONE. 2015;10:e0127681 pubmed publisher
    ..Previous work by us and others has provided crucial insights into the key function of Mgn and Mash1 genes in determining GABAergic neurotransmitter fate...
  44. Balafa O, Kalaitzidis R, Liapis G, Xiromeriti S, Zarzoulas F, Baltatzis G, et al. Crescentic glomerulonephritis and membranous nephropathy: a rare coexistence. Int Urol Nephrol. 2015;47:1373-7 pubmed publisher
    The coexistence of crescents and membranous glomerulonephritis (MGN) is a special characteristic in lupus nephritis...
  45. Regmi P, Holgate B, Miller M, Park H, Chandran K, Wett B, et al. Nitrogen polishing in a fully anoxic anammox MBBR treating mainstream nitritation-denitritation effluent. Biotechnol Bioeng. 2016;113:635-42 pubmed publisher
    ..7 ± 0.59 mgN/L, ammonia = 6.13 ± 2.86 mgN/L, nitrate = 3...
  46. Cui H, Schlesinger J, Schoenhals S, Tönjes M, Dunkel I, Meierhofer D, et al. Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Res. 2016;44:2538-53 pubmed publisher
    ..Thus, we present a novel pathway for pathological cardiac hypertrophy, whose inhibition is a long-term therapeutic goal for the treatment of the course of heart failure. ..
  47. Hiramatsu R, Ubara Y, Sawa N, Hasegawa E, Kawada M, Imafuku A, et al. Clinicopathological analysis of allogeneic hematopoietic stem cell transplantation-related membranous glomerulonephritis. Hum Pathol. 2016;50:187-94 pubmed publisher
    Allogeneic hematopoietic stem cell transplantation (HSCT)-related membranous glomerulonephritis (MGN) is poorly understood...
  48. Hulsen T, Barry E, Lu Y, Puyol D, Keller J, Batstone D. Domestic wastewater treatment with purple phototrophic bacteria using a novel continuous photo anaerobic membrane bioreactor. Water Res. 2016;100:486-495 pubmed publisher
    ..This process could continuously treat domestic wastewater to discharge limits (<50 mgCOD L(-1), 5 mgN L(-1), 1.0 mgP L(-1)). Approximately 6.4 ± 1.3 gNH4-N and 1.1 ± 0...
  49. Zheng K, Teng F, Li X. Immunoglobulin G4-related kidney disease: Pathogenesis, diagnosis, and treatment. Chronic Dis Transl Med. 2017;3:138-147 pubmed publisher
    ..renal manifestations of IgG4-RD are IgG4-related tubulointerstitial nephritis, membranous glomerulonephropathy (MGN), and obstructive nephropathy secondary to urinary tract obstruction due to IgG4-related retroperitoneal fibrosis, ..
  50. Benck U, Banas B, Birck R. [Primary and Secondary Glomerular Diseases - Update 2017]. Dtsch Med Wochenschr. 2017;142:1832-1836 pubmed publisher
    ..Die pathogenetisch kausale Rolle dieser MGN-assoziierten Auto-Antikörper ist bewiesen...
  51. Velho V, Magnus B, Daudt G, Xavier J, Guimarães L, Costa R. Effect of COD/N ratio on N2O production during nitrogen removal by aerobic granular sludge. Water Sci Technol. 2017;76:3452-3460 pubmed publisher
    ..55), the N2O production (1.08 mgN2O-N L-1) and consumption (up to 0...
  52. Fujita K, Hatta K. Membranous glomerulonephritis with an LMNA mutation. CEN Case Rep. 2018;7:98-100 pubmed publisher
    We had encountered the case of membranous glomerulonephritis (MGN) with dilated cardiomyopathy due to LMNA gene mutation...
  53. Iasimone F, Zuccaro G, D Oriano V, Franci G, Galdiero M, Pirozzi D, et al. Combined yeast and microalgal cultivation in a pilot-scale raceway pond for urban wastewater treatment and potential biodiesel production. Water Sci Technol. 2018;77:1062-1071 pubmed publisher
    ..Complete nutrient removal occurred during microalgal linear growth with 2.9 mgN L-1 d-1 and 0.96 mgP L-1 d-1 removal rates...
  54. Katoh M, Katoh M. Identification and characterization of human HESL, rat Hesl and rainbow trout hesl genes in silico. Int J Mol Med. 2004;14:747-51 pubmed
    ..Here, we identified and characterized human HES-like (HESL), rat Fesl, and rainbow trout fesl genes by using bioinformatics. Human HESL gene, located within AC093824...
  55. Khaira A, Upadhyay B, Sharma A, Das P, Mahajan S, Makhariya G, et al. Hepatitis B virus associated focal and segmental glomerular sclerosis: report of two cases and review of literature. Clin Exp Nephrol. 2009;13:373-377 pubmed publisher
    ..and usually manifests in the form of immune complex mediated glomerulopathy, such as membranous glomerulonephritis (MGN), membranoproliferative glomerulonephritis (MPGN), mesangioproliferative glomerulonephritis and immunoglobulin A (..
  56. Regmi P, Bunce R, Miller M, Park H, Chandran K, Wett B, et al. Ammonia-based intermittent aeration control optimized for efficient nitrogen removal. Biotechnol Bioeng. 2015;112:2060-7 pubmed publisher
    ..was also obtained (ammonia oxidizing bacteria [AOB] maximum activity: 400 ± 79 mgN/L/d, NOB maximum activity: 257 ± 133 mgN/L/d, P < 0...
  57. van der Steen P, Rahsilawati K, Rada Ariza A, Lopez Vazquez C, Lens P. A new photo-activated sludge system for nitrification by an algal-bacterial consortium in a photo-bioreactor with biomass recycle. Water Sci Technol. 2015;72:443-50 pubmed publisher
    ..The PAS consisted of a mixed photo-bioreactor, continuously fed with BG-11 medium, adjusted to 66 mgN-NH4⁺/l...
  58. Badr El Din N, Abdel Fattah S, Pan D, Tolentino L, Ghoneum M. Chemopreventive Activity of MGN-3/Biobran Against Chemical Induction of Glandular Stomach Carcinogenesis in Rats and Its Apoptotic Effect in Gastric Cancer Cells. Integr Cancer Ther. 2016;15:NP26-NP34 pubmed
    In the current study, we investigated the chemopreventive activity of arabinoxylan rice bran, MGN-3/Biobran, against chemical induction of glandular stomach carcinogenesis in rats...
  59. Wang Y, Bott C, Nerenberg R. Sulfur-based denitrification: Effect of biofilm development on denitrification fluxes. Water Res. 2016;100:184-193 pubmed publisher
    ..1 mgN/L at 21 days to 0...
  60. Lee J, Lee Y, Kim S, Kim Y, Moon J, Jeong K, et al. Systematic biomarker discovery and coordinative validation for different primary nephrotic syndromes using gas chromatography-mass spectrometry. J Chromatogr A. 2016;1453:105-15 pubmed publisher
    ..by minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and membranous glomerulonephritis (MGN)...
  61. Perkowska Ptasinska A, Deborska Materkowska D, Bartczak A, Stompor T, Liberek T, Bullo Piontecka B, et al. Kidney disease in the elderly: biopsy based data from 14 renal centers in Poland. BMC Nephrol. 2016;17:194 pubmed
    ..2%) and the most prevalent pathologic diagnoses were: membranous glomerulonephritis (MGN) (18.2%), focal segmental glomerulosclerosis (FSGS) (17.3%) amyloidosis (13...
  62. Kim H, Hong Y, Kim Y, Kim H, Park J, Do J, et al. Anti-heparan sulfate antibody and functional loss of glomerular heparan sulfate proteoglycans in lupus nephritis. Lupus. 2017;26:815-824 pubmed publisher
    ..performed for histological evaluation of GBM HSPGs in normal glomeruli, non-lupus membranous glomerulonephritis (MGN), and lupus MGN...
  63. Scott B, Saleem K, Kikuchi Y, Fukushima M, Mishkin M, Saunders R. Thalamic connections of the core auditory cortex and rostral supratemporal plane in the macaque monkey. J Comp Neurol. 2017;525:3488-3513 pubmed publisher
    ..connections, the auditory cortex receives parallel thalamocortical projections from the medial geniculate nucleus (MGN)...
  64. Kee Y, Yoon C, Kim S, Moon S, Kim C, Park J, et al. Determination of the optimal target level of proteinuria in the management of patients with glomerular diseases by using different definitions of proteinuria. Medicine (Baltimore). 2017;96:e8154 pubmed publisher
    ..We analyzed 574 IgA nephropathy (IgAN), 175 membranous nephropathy (MGN), and 177 focal segmental glomerulosclerosis (FSGS) cases from 3 Korean kidney centers...
  65. Meydanli M, Erguvan R, Altinok M, Ataoglu O, Kafkasli A. Rare case of neuroendocrine small cell carcinoma of the endometrium with paraneoplastic membranous glomerulonephritis. Tumori. 2003;89:213-7 pubmed
    ..a case of neuroendocrine small cell carcinoma of the endometrium associated with membranous glomerulonephritis (MGN), which appeared to be a component of an unusual paraneoplastic syndrome...
  66. Huang M, Pan C, Ma H. Ring-opening polymerization of rac-lactide and α-methyltrimethylene carbonate catalyzed by magnesium and zinc complexes derived from binaphthyl-based iminophenolate ligands. Dalton Trans. 2015;44:12420-31 pubmed publisher
    ..of Mg[N(SiMe3)2]2 or Zn[N(SiMe3)2]2 to provide three heteroleptic magnesium silylamido complexes [(L4–(6))MgN(SiMe3)2] (4a: R(1) = R(2) = cumyl; 5a: R(1) = CPh3, R(2) = Me; 6a: R(1) = CPh3, R(2) = (t)Bu) and one heteroleptic ..
  67. Barry K, Paolini A, Robertson D, Mulders W. Modulation of medial geniculate nucleus neuronal activity by electrical stimulation of the nucleus accumbens. Neuroscience. 2015;308:1-10 pubmed publisher
    ..loss, is the result of a breakdown of circuitry involving the limbic system and the medial geniculate nucleus (MGN) of the thalamus...
  68. Sha W, Shen L, Zhou L, Xu D, Lu G. Down-regulation of miR-186 contributes to podocytes apoptosis in membranous nephropathy. Biomed Pharmacother. 2015;75:179-84 pubmed publisher
    ..Here we investigated the expression of miR-186 in membranous nephropathy (MGN) patients and the mechanism underlying the podocytes apoptosis...
  69. Beyar Katz O, Davila E, Zuckerman T, Fineman R, Haddad N, Okasha D, et al. Adult Nephrotic Syndrome after Hematopoietic Stem Cell Transplantation: Renal Pathology is the Best Predictor of Response to Therapy. Biol Blood Marrow Transplant. 2016;22:975-981 pubmed publisher
    ..NS development was associated with acute or chronic GVHD in 87.2% of cases. Membranous nephropathy (MGN) was the most frequent pathology (65.5%), followed by minimal change disease (MCD) (19%)...
  70. Laureni M, Falås P, Robin O, Wick A, Weissbrodt D, Nielsen J, et al. Mainstream partial nitritation and anammox: long-term process stability and effluent quality at low temperatures. Water Res. 2016;101:628-639 pubmed publisher
    ..Promising nitrogen removal rates of 20-40 mgN·L(-1)·d(-1) were maintained at hydraulic retention times of 14 h...
  71. Badr El Din N, Ali D, Alaa El Dein M, Ghoneum M. Enhancing the Apoptotic Effect of a Low Dose of Paclitaxel on Tumor Cells in Mice by Arabinoxylan Rice Bran (MGN-3/Biobran). Nutr Cancer. 2016;68:1010-20 pubmed publisher
    In this study, we examine the ability of arabinoxylan rice bran (MGN-3/Biobran) to enhance the apoptotic effect of paclitaxel (Taxol) at low concentration [2 mg/kg body weight (BW)] in animals bearing Ehrlich ascites carcinoma (EAC) ..
  72. Dutta N, Biswas S, Saha M. Biophysical characterization and activity analysis of nano-magnesium supplemented cellulase obtained from a psychrobacterium following graphene oxide immobilization. Enzyme Microb Technol. 2016;95:248-258 pubmed publisher
    ..The native enzyme showed optimum activity at 15°C and pH 8.0.The Magnesium oxide nanoparticle (MgN) supplemented enzyme when immobilized on graphene oxide nanosupport (GO), via glutaraldehyde as cross linker, ..
  73. Beversdorf L, Weirich C, Bartlett S, Miller T. Variable Cyanobacterial Toxin and Metabolite  Profiles across Six Eutrophic Lakes of Differing  Physiochemical Characteristics. Toxins (Basel). 2017;9: pubmed publisher
    ..anabaenopeptins (Apt), three cyanopeptolins (Cpt), microginin (Mgn), and nodularin (NOD)-in  six freshwater lakes that regularly experience noxious cHABs...
  74. Lu Y, Liaquat R, Astals S, Jensen P, Batstone D, Tait S. Relationship between microbial community, operational factors and ammonia inhibition resilience in anaerobic digesters at low and moderate ammonia background concentrations. N Biotechnol. 2018;44:23-30 pubmed publisher
    ..1-241 mgN·L-1)...
  75. Nakatani T, Mizuhara E, Minaki Y, Sakamoto Y, Ono Y. Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system. J Biol Chem. 2004;279:16356-67 pubmed
    ..Here, we report the identification of a novel transcriptional repressor, designated Helt. Helt encoded a Hey-related bHLH protein containing the bHLH and Orange domains...
  76. Rodríguez Andrade O, Fuentes Ramírez L, Morales García Y, Molina Romero D, Bustillos Cristales M, Martínez Contreras R, et al. The decrease in the population of Gluconacetobacter diazotrophicus in sugarcane after nitrogen fertilization is related to plant physiology in split root experiments. Rev Argent Microbiol. 2015;47:335-43 pubmed publisher
    ..3mM; 180 mgN/plant) on one end of the system. This nitrogen level was lower than that directly affecting G...
  77. Wu J, Liu B, Liang C, Ouyang H, Lin J, Zhong Y, et al. Zhen-wu-tang attenuates cationic bovine serum albumin-induced inflammatory response in membranous glomerulonephritis rat through inhibiting AGEs/RAGE/NF-κB pathway activation. Int Immunopharmacol. 2016;33:33-41 pubmed publisher
    ..signaling pathway in rats with cationic bovine serum albumin (C-BSA)-induced membranous glomerulonephritis (MGN)...
  78. Kalaruban M, Loganathan P, Shim W, Kandasamy J, Ngo H, Vigneswaran S. Enhanced removal of nitrate from water using amine-grafted agricultural wastes. Sci Total Environ. 2016;565:503-510 pubmed publisher
    ..The Langmuir nitrate adsorption capacities (mgN/g) were 49.9 and 59.0 for the amine-grafted (AG) corn cob and coconut copra, respectively at pH6...
  79. Federherr E, Kupka H, Cerli C, Kalbitz K, Dunsbach R, Loos A, et al. A novel tool for stable nitrogen isotope analysis in aqueous samples. Rapid Commun Mass Spectrom. 2016;: pubmed publisher
    ..5‰. Good results (u ? 0.5‰) could be achieved down to a TNb concentration of 40 mgN/L and acceptable results (u ? 1.0‰) down to 5 mgN/L...
  80. Kaneko T, Shimizu A, Aoki M, Tsuruoka S. A case of gefitinib-associated membranous nephropathy in treatment for pulmonary adenocarcinoma. CEN Case Rep. 2015;4:31-37 pubmed publisher
    We experienced a case that was considered as gefitinib-associated membranous nephropathy (MGN) in treatment for pulmonary adenocarcinoma...
  81. Malakootikhah J, Rezayan A, Negahdari B, Nasseri S, Rastegar H. Glucose reinforced Fe3O4@cellulose mediated amino acid: Reusable magnetic glyconanoparticles with enhanced bacteria capture efficiency. Carbohydr Polym. 2017;170:190-197 pubmed publisher
    In this study glucose reinforced Fe3O4@cellulose glyconanoparticles (MGN) were prepared using epichlorohydrin and amino acid (lysine and arginine) as a linker...
  82. Miyoshi G, Bessho Y, Yamada S, Kageyama R. Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis. J Neurosci. 2004;24:3672-82 pubmed
    ..These results suggest that combinations of distinct bHLH factors promote formation of distinct neuronal subtypes, thereby increasing neuronal diversity. ..
  83. Cattran D, Kim E, Reich H, Hladunewich M, Kim S. Membranous Nephropathy: Quantifying Remission Duration on Outcome. J Am Soc Nephrol. 2017;28:995-1003 pubmed publisher
    Although change in proteinuria has been proposed as a surrogate for long-term prognosis in membranous nephropathy (MGN), variability in proteinuria levels and lag between these changes and acceptable end points, such as ESRD, has limited ..
  84. Mielcarek A, Rodziewicz J, Janczukowicz W, DABROWSKA D, Ciesielski S, Thornton A, et al. Citric acid application for denitrification process support in biofilm reactor. Chemosphere. 2017;171:512-519 pubmed publisher
    ..5 mgCOD L-1 h-1 and 17.81 mgN L-1 h-1, respectively) than under the steady state conditions (cycles 61-180; 143...
  85. Barry K, Robertson D, Mulders W. Medial geniculate neurons show diverse effects in response to electrical stimulation of prefrontal cortex. Hear Res. 2017;353:204-212 pubmed publisher
    ..from altered cortico-limbic circuitry and its connection with the auditory thalamus, the medial geniculate nucleus (MGN)...
  86. Ferrara N, Cullen P, Pullins S, Rotondo E, Helmstetter F. Input from the medial geniculate nucleus modulates amygdala encoding of fear memory discrimination. Learn Mem. 2017;24:414-421 pubmed publisher
    ..The amygdala receives input from auditory cortex as well as the medial geniculate nucleus (MgN) of the thalamus, and these synapses undergo plastic changes in response to fear conditioning and are major ..
  87. Cheng C, Zhang J, Li S, Xia Y, Nie C, Shi Z, et al. A Water-Processable and Bioactive Multivalent Graphene Nanoink for Highly Flexible Bioelectronic Films and Nanofibers. Adv Mater. 2017;: pubmed publisher
    ..Here, a facile and scalable synthesis of supramolecular-functionalized multivalent graphene nanoink (mGN-ink) via [2+1] nitrene cycloaddition is reported...
  88. Nakatani T, Minaki Y, Kumai M, Ono Y. Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. Development. 2007;134:2783-93 pubmed
    ..Here, we show in mice that the basic helix-loop-helix transcriptional repressor gene Helt (also known as Megane and Heslike) functions as a selector gene that determines GABAergic over glutamatergic fate ..
  89. Sim J, Batech M, Hever A, Harrison T, Avelar T, Kanter M, et al. Distribution of Biopsy-Proven Presumed Primary Glomerulonephropathies in 2000-2011 Among a Racially and Ethnically Diverse US Population. Am J Kidney Dis. 2016;68:533-544 pubmed publisher
    ..had kidney biopsy findings demonstrating focal segmental glomerulosclerosis (FSGS), membranous glomerulonephritis (MGN), minimal change disease (MCD), immunoglobulin A nephropathy (IgAN), and other...
  90. Wang H, Guo J, Yang Y, Ma H. Diastereoselective synthesis of chiral aminophenolate magnesium complexes and their application in the stereoselective polymerization of rac-lactide and rac-?-butyrolactone. Dalton Trans. 2016;45:10942-53 pubmed publisher
    ..in a 1?:?1 molar ratio in toluene gave the chiral aminophenolate magnesium silylamido complexes L(1-10)MgN(SiMe3)2 as enantiopure compounds or as pairs of diastereomers...
  91. Yabuuchi J, Suwabe T, Mizuno H, Ueno T, Hoshino J, Sekine A, et al. Long-term Low-density Lipoprotein Apheresis in a Patient with Refractory Idiopathic Membranous Glomerulonephritis. Intern Med. 2017;56:1543-1547 pubmed publisher
    A 61-year-old Japanese man developed nephrotic syndrome (NS) due to idiopathic membranous glomerulonephritis (MGN)...
  92. Papias S, Masson M, Pelletant S, Prost Boucle S, Boutin C. In situ continuous monitoring of nitrogen with ion-selective electrodes in a constructed wetland receiving treated wastewater: an operating protocol to obtain reliable data. Water Sci Technol. 2018;77:1706-1713 pubmed publisher
    ..complementary calibration using CWtw water, a drift evaluation and the determination of limits of quantification (1 mgN/L for ammonium and 0.5 mgN/L for nitrate)...