GALNT9

Summary

Gene Symbol: GALNT9
Description: polypeptide N-acetylgalactosaminyltransferase 9
Alias: GALNAC-T9, GALNACT9, polypeptide N-acetylgalactosaminyltransferase 9, GalNAc transferase 9, UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 9, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9), polypeptide GalNAc transferase 9, pp-GaNTase 9, protein-UDP acetylgalactosaminyltransferase 9
Species: human
Products:     GALNT9

Top Publications

  1. Tuupanen S, Hänninen U, Kondelin J, von Nandelstadh P, Cajuso T, Gylfe A, et al. Identification of 33 candidate oncogenes by screening for base-specific mutations. Br J Cancer. 2014;111:1657-62 pubmed publisher
    ..Fourteen genes displayed mutations in the validation set of 254 MSI CRCs: ANTXR1, MORC2, CEP135, CRYBB1, GALNT9, KRT82, PI15, SLC36A1, CNTF, GLDC, MBTPS1, OR9Q2, R3HDM1 and TTPAL...
  2. Zhou C, Feng X, Yuan F, Ji J, Shi M, Yu Y, et al. Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis. Cancer Manag Res. 2018;10:3945-3954 pubmed publisher
    ..Amplifications of solute carrier family 12 member 7 (SLC12A7, 5/5), TTC40 (4/5) and GALNT9 (4/5) genes were mainly detected in HER2- samples...
  3. Gillman A, Gardiner C, Koljack C, Bryan A. Body mass index, diet, and exercise: testing possible linkages to breast cancer risk via DNA methylation. Breast Cancer Res Treat. 2018;168:241-248 pubmed publisher
    ..which were analyzed to ascertain average methylation of candidate genes related to breast cancer (BRCA1, RUNX3, GALNT9, and PAX6) and inflammation (TLR4 and TLR6). Elevated weight status (r = - .18, p < ...
  4. Wan Y, Jin S, Ma C, Wang Z, Fang Q, Jiang R. RNA-Seq reveals seven promising candidate genes affecting the proportion of thick egg albumen in layer-type chickens. Sci Rep. 2017;7:18083 pubmed publisher
    ..Based on functional analysis, ST3GAL4, FUT4, ITGA2, SDC3, PRLR, CDH4 and GALNT9 were identified as promising candidate genes for thick albumen synthesis and metabolism during egg formation...
  5. Toba S, Tenno M, Konishi M, Mikami T, Itoh N, Kurosaka A. Brain-specific expression of a novel human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T9). Biochim Biophys Acta. 2000;1493:264-8 pubmed
    ..Northern blot analysis revealed the mRNA expression of the enzyme to be confined to the brain. The brain-specific expression of GalNAc-T9 suggested that this isozyme catalyzes O-glycosylation in the brain. ..
  6. Berois N, Gattolliat C, Barrios E, Capandeguy L, Douc Rasy S, Valteau Couanet D, et al. GALNT9 gene expression is a prognostic marker in neuroblastoma patients. Clin Chem. 2013;59:225-33 pubmed publisher
    ..We assessed the expression of genes in the GALNT family in a large cohort of neuroblastoma patients and characterized members of this family that might be used as new prognostic markers...
  7. Gu Y, Zhou X, Hu F, Yu Y, Xie T, Huang Y, et al. Differential DNA methylome profiling of nonfunctioning pituitary adenomas suggesting tumour invasion is correlated with cell adhesion. J Neurooncol. 2016;129:23-31 pubmed publisher
    ..The mRNA expression of GALNT9 which contain a validated DMS was significantly downregulated in invasive group...
  8. Zhang Y, Iwasaki H, Wang H, Kudo T, Kalka T, Hennet T, et al. Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen. J Biol Chem. 2003;278:573-84 pubmed
    ..pp-GalNAc-T13 would be a major enzyme responsible for the synthesis of O-glycan and specifically the Tn antigen epitope in neurons. ..
  9. Sheta R, Bachvarova M, Plante M, Gregoire J, Renaud M, Sebastianelli A, et al. Altered expression of different GalNAc?transferases is associated with disease progression and poor prognosis in women with high-grade serous ovarian cancer. Int J Oncol. 2017;51:1887-1897 pubmed publisher
    ..These observations were confirmed by IHC. GALNT2 displayed significantly lower expression, while GALNT6, GALNT9 and GALNT14 showed significantly higher expression in HGSC tumors compared to control tissue...