Gene Symbol: FRMPD2
Description: FERM and PDZ domain containing 2
Alias: PDZD5C, PDZK4, PDZK5C, FERM and PDZ domain-containing protein 2, PDZ domain containing 5C, PDZ domain-containing protein 4
Bhalla S, Chaudhary K, Kumar R, Sehgal M, Kaur H, Sharma S, et al
. Gene expression-based biomarkers for discriminating early and late stage of clear cell renal cancer. Sci Rep. 2017;7:44997 pubmed publisher
..These eight genes include four underexpressed (NR3C2, ENAM, DNASE1L3, FRMPD2) and four overexpressed (PLEKHA9, MAP6D1, SMPD4, C11orf73) genes in the late stage of ccRCC...
Ueno A, Omori Y, Sugita Y, Watanabe S, Chaya T, Kozuka T, et al
. Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity. Cell Rep. 2018;22:3548-3561 pubmed publisher
..Furthermore, we demonstrated that Lrit1 interacts with Frmpd2, a photoreceptor scaffold protein, and with mGluR6, an ON-bipolar cell-specific glutamate receptor...
Stenzel N, Fetzer C, Heumann R, Erdmann K. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. J Cell Sci. 2009;122:3374-84 pubmed publisher
..The novel multi-PDZ domain protein FRMPD2 is a potential scaffolding protein consisting of an N-terminal KIND domain, a FERM domain and three PDZ domains...
Huang J, Furuya A, Hayashi K, Furuichi T. Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain. FEBS J. 2011;278:1651-61 pubmed publisher
..Four KIND-containing proteins, Spir-2 (actin-nuclear factor), PTPN13 (protein tyrosine phosphatase), FRMPD2 (scaffold protein) and very-KIND (v-KIND) (brain-specific Ras guanine nucleotide exchange factor), have been ..
Lipinski S, Grabe N, Jacobs G, Billmann Born S, Till A, Häsler R, et al
. RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition. Proc Natl Acad Sci U S A. 2012;109:21426-31 pubmed publisher
..a set of 20 positive NF-?B regulators including the known pathway members RIPK2, RELA, and BIRC4 (XIAP) as well as FRMPD2 (FERM and PDZ domain-containing 2)...