FLNB

Summary

Gene Symbol: FLNB
Description: filamin B
Alias: ABP-278, ABP-280, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP, filamin-B, ABP-280 homolog, Larsen syndrome 1 (autosomal dominant), actin binding protein 278, actin-binding-like protein, beta-filamin, filamin B, beta, filamin homolog 1, filamin-3, thyroid autoantigen
Species: human
Products:     FLNB

Top Publications

  1. Zhang W, Han S, McKeel D, Goate A, Wu J. Interaction of presenilins with the filamin family of actin-binding proteins. J Neurosci. 1998;18:914-22 pubmed
    ..PS2 interact with nonmuscle filamin (actin-binding protein 280, ABP280) and a structurally related protein (filamin homolog 1, Fh1). Overexpression of PS1 appears to modify the distribution of ABP280 and Fh1 proteins in cultured cells...
  2. Xu W, Xie Z, Chung D, Davie E. A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha. Blood. 1998;92:1268-76 pubmed
    ..ABP-276 and/or ABP-278 were present in all tissues examined, but the relative amount varied in that some tissue contained both forms, while other tissue contained predominately one or the other. ..
  3. Stossel T, Condeelis J, Cooley L, Hartwig J, Noegel A, Schleicher M, et al. Filamins as integrators of cell mechanics and signalling. Nat Rev Mol Cell Biol. 2001;2:138-45 pubmed
    ..They integrate cellular architectural and signalling functions and are essential for fetal development and cell locomotion. Here, we describe the history, structure and function of this group of proteins. ..
  4. Bicknell L, Morgan T, Bonafe L, Wessels M, Bialer M, Willems P, et al. Mutations in FLNB cause boomerang dysplasia. J Med Genet. 2005;42:e43 pubmed
    ..shown to be associated with mutations in FLNB, the gene encoding the actin binding cytoskeletal protein, filamin B. We report the identification of mutations in FLNB in two unrelated individuals with boomerang dysplasia...
  5. Li G, Kung A, Huang Q. Common variants in FLNB/CRTAP, not ARHGEF3 at 3p, are associated with osteoporosis in southern Chinese women. Osteoporos Int. 2010;21:1009-20 pubmed publisher
    ..Polymorphisms in FLNB/CRTAP are associated with bone mineral density (BMD) in Chinese...
  6. Takafuta T, Wu G, Murphy G, Shapiro S. Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha. J Biol Chem. 1998;273:17531-8 pubmed
    ..beta-Filamin is a new member of the filamin family that may have significance for GpIbalpha function in endothelial cells and platelets. ..
  7. Chakarova C, Wehnert M, Uhl K, Sakthivel S, Vosberg H, van der Ven P, et al. Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family. Hum Genet. 2000;107:597-611 pubmed
    The genomic structure of the filamin gene paralogues FLNB and FLNC was determined and related to FLNA. FLNB consists of 45 exons and 44 introns and spans approximately 80 kb of genomic DNA...
  8. van Der Flier A, Sonnenberg A. Structural and functional aspects of filamins. Biochim Biophys Acta. 2001;1538:99-117 pubmed
    ..In this review aspects of filamin structure, its splice variants, binding partners and biological function will be discussed. ..
  9. Kato S, Ohtoko K, Ohtake H, Kimura T. Vector-capping: a simple method for preparing a high-quality full-length cDNA library. DNA Res. 2005;12:53-62 pubmed
    ..5 kbp can be cloned. This method will accelerate comprehensive gene analysis in a variety of eukaryotes. ..

More Information

Publications130 found, 100 shown here

  1. Bicknell L, Farrington Rock C, Shafeghati Y, Rump P, Alanay Y, Alembik Y, et al. A molecular and clinical study of Larsen syndrome caused by mutations in FLNB. J Med Genet. 2007;44:89-98 pubmed
    ..shown to be caused by missense mutations or small inframe deletions in FLNB, encoding the cytoskeletal protein filamin B. To further delineate the molecular causes of Larsen syndrome, 20 probands with Larsen syndrome together with ..
  2. Mitter D, Krakow D, Farrington Rock C, Meinecke P. Expanded clinical spectrum of spondylocarpotarsal synostosis syndrome and possible manifestation in a heterozygous father. Am J Med Genet A. 2008;146A:779-83 pubmed publisher
    ..The patient's father has mild short stature and unilateral hip dysplasia. Molecular studies of the filamin B gene (FLNB) revealed a homozygous mutation in the index patient while both parents were heterozygous for the ..
  3. Krakow D, Robertson S, King L, Morgan T, Sebald E, Bertolotto C, et al. Mutations in the gene encoding filamin B disrupt vertebral segmentation, joint formation and skeletogenesis. Nat Genet. 2004;36:405-10 pubmed
    ..1,2). We identified mutations in the gene encoding filamin B in four human skeletal disorders...
  4. Farrington Rock C, Firestein M, Bicknell L, Superti Furga A, Bacino C, Cormier Daire V, et al. Mutations in two regions of FLNB result in atelosteogenesis I and III. Hum Mutat. 2006;27:705-10 pubmed
    ..Mutations in the gene encoding filamin B (FLNB) cause a spectrum of osteochondrodysplasias, including atelosteogenesis type I (AOI) and atelosteogenesis ..
  5. Lei S, Tan L, Liu X, Wang L, Yan H, Guo Y, et al. Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation. Hum Mol Genet. 2009;18:1661-9 pubmed publisher
    ..034-0.042). Three SNPs in another SNP group in the Filamin B (FLNB) gene were also associated with stature, significantly so with FDR q = 0.042-0.048...
  6. Wilson S, Jones M, Mullin B, Dick I, Richards J, Pastinen T, et al. Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro. J Bone Miner Res. 2009;24:1989-97 pubmed publisher
    Previous data from our group indicate that BMD is linked to chromosome 3p14-p21. Because the filamin B (FLNB gene resides in this region, is the cause of skeletal dysplasias, and was identified among the top genes in our bioinformatics ..
  7. Kaushansky K, Zhan H. The regulation of normal and neoplastic hematopoiesis is dependent on microenvironmental cells. Adv Biol Regul. 2018;69:11-15 pubmed publisher
    ..myeloablation with conditioning therapy or immunological means, followed by allogeneic stem cell transplantation (SCT), a procedure that is often inadequate due to relapse of the malignant clone...
  8. Saleem S, Khan R, Afzal M, Kazmi I. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/?-catenin signaling pathway. Mol Cell Biochem. 2018;444:187-196 pubmed publisher
    ..1% in tap water) for promoting tumorigenesis throughout the study. MTX (2.5 and 5...
  9. Oyagbemi A, Omobowale T, Asenuga E, Adejumobi A, Ajibade T, Ige T, et al. Sodium fluoride induces hypertension and cardiac complications through generation of reactive oxygen species and activation of nuclear factor kappa beta. Environ Toxicol. 2017;32:1089-1101 pubmed publisher
    ..Group A received clean tap water...
  10. Riise N, Lindberg B, Kulseth M, Fredwall S, Lundby R, Estensen M, et al. Clinical diagnosis of Larsen syndrome, Stickler syndrome and Loeys-Dietz syndrome in a 19-year old male: a case report. BMC Med Genet. 2018;19:155 pubmed publisher
    ..The autosomal dominant type is caused by mutations in the gene that encodes the connective tissue protein, filamin B (FLNB)...
  11. Ikegame K, Imai K, Yamashita M, Hoshino A, Kanegane H, Morio T, et al. Allogeneic stem cell transplantation for X-linked agammaglobulinemia using reduced intensity conditioning as a model of the reconstitution of humoral immunity. J Hematol Oncol. 2016;9:9 pubmed publisher
    ..CD19(+) cells, IgA, and IgM, which were undetectable before allogeneic stem cell transplantation (allo-SCT), started to increase in number 10 days after allo-SCT and continued to increase for more than 1 year...
  12. Ali D, El Sayyad H, Moftah O, Chilibeck P. Structural and functional abnormalities of hepatic tissues in male Wistar rats fed hyperwhey and super amino anabolic protein. Nutrition. 2016;32:840-8 pubmed publisher
    ..Launderale, FL, USA) (2.5 g/kg body weight). The applied dose was orally administered daily in tap water for 14 wk. Body weight was regularly measured. At 14 wk, animals were sacrificed and dissected...
  13. Huc T, Jurkowska H, Wróbel M, Jaworska K, Onyszkiewicz M, Ufnal M. Colonic hydrogen sulfide produces portal hypertension and systemic hypotension in rats. Exp Biol Med (Maywood). 2018;243:96-106 pubmed publisher
    ..Sprague-Dawley rats were maintained either on tap water (controls) or on water solution of thioacetamide to produce liver cirrhosis (CRH-R)...
  14. Yang X, Zou W, Zeng J, Xie S, An T, Luo X, et al. Prevalence of antimicrobial resistance and integron gene cassettes in Escherichia coli isolated from yaks (Poephagus grunniens) in Aba Tibetan Autonomous Prefecture, China. Microb Pathog. 2017;111:274-279 pubmed publisher
    ..coli isolated from yaks in Aba Tibetan Autonomous Prefecture (Aba TAP), China...
  15. Contini M, Fabro A, Millen N, Benmelej A, Mahieu S. Adverse effects in kidney function, antioxidant systems and histopathology in rats receiving monosodium glutamate diet. Exp Toxicol Pathol. 2017;69:547-556 pubmed publisher
    ..35% NaCl solution permanently alone at the same frequency and time; 3) control group were fed the normal chow and tap water...
  16. Benhelima A, Kaid Omar Z, Hemida H, Benmahdi T, Addou A. NEPHROPROTECTIVE AND DIURETIC EFFECT OF NIGELLA SATIVA L SEEDS OIL ON LITHIASIC WISTAR RATS. Afr J Tradit Complement Altern Med. 2016;13:204-214 pubmed publisher
    ..Thirty male Wistar rats were divided into 5 groups (N=6). Group I, negative control, drank tap water...
  17. Morer C, Roques C, Francon A, Forestier R, Maraver F. The role of mineral elements and other chemical compounds used in balneology: data from double-blind randomized clinical trials. Int J Biometeorol. 2017;61:2159-2173 pubmed publisher
    ..double-blind randomized clinical trials that assessed the effects of mineral water or mud treatments compared to tap water, attenuated peloid/mud therapy or similar treatments without the specific minerals or chemical compounds of ..
  18. Yamakawa T, Ohigashi H, Hashimoto D, Hayase E, Takahashi S, Miyazaki M, et al. Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease. Blood. 2018;: pubmed publisher
    Chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (SCT) is characterized by multiple-organ fibrosis, profoundly affects quality of life of transplant survivors...
  19. Kennedy G, Varelias A, Vuckovic S, Le Texier L, Gartlan K, Zhang P, et al. Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial. Lancet Oncol. 2014;15:1451-9 pubmed publisher
    ..6 mediates graft-versus-host disease (GVHD) in experimental allogeneic stem-cell transplantation (allogeneic SCT) and represents an attractive therapeutic target...
  20. Koh E, Kim J, Song S, Sung J, Lee H, Kim K, et al. Ethanol extracts collected from the Styela clava tunic alleviate hepatic injury induced by carbon tetrachloride (CCl4) through inhibition of hepatic apoptosis, inflammation, and fibrosis. J Toxicol Pathol. 2017;30:291-306 pubmed publisher
    The Styela clava tunic (SCT) is known as a good raw material for preparing anti-inflammatory compounds, wound healing films, guided bone regeneration, and food additives...
  21. Lian J, Ren L, Zhang C, Yu C, Huang Z, Xu A, et al. How exposure to ALS-inhibiting gametocide tribenuron-methyl induces male sterility in rapeseed. BMC Plant Biol. 2019;19:124 pubmed publisher
    ..protein LTP11 and LTP12, histone-lysine N-methyltransferase ATXR6, spermidine coumaroyl-CoA acyltransferase (SCT), and photosystem II reaction centre protein psbB, were downregulated by TBM exposure...
  22. Abdel Daim M, Eissa I, Abdeen A, Abdel Latif H, Ismail M, Dawood M, et al. Lycopene and resveratrol ameliorate zinc oxide nanoparticles-induced oxidative stress in Nile tilapia, Oreochromis niloticus. Environ Toxicol Pharmacol. 2019;69:44-50 pubmed publisher
    ..Five groups with 20 fish each were used; Control, received tap water only; ZnONP group, was intoxicated with ZnONP (50 mg/L); ZnONP-LYC group, was exposed to ZnONP and LYC (500..
  23. Prince P, Santander Y, Geréz E, Hocht C, Polizio A, Mayer M, et al. Fructose increases corticosterone production in association with NADPH metabolism alterations in rat epididymal white adipose tissue. J Nutr Biochem. 2017;46:109-116 pubmed publisher
    ..Male Sprague-Dawley rats fed with a fructose solution (10% (w/v) in tap water) during 9 weeks developed some characteristic features of metabolic syndrome, such as hypertriglyceridemia, ..
  24. Kuo K, Wu B, Liu C, Yang T, Kao L, Wu J, et al. Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. J Lipid Res. 2015;56:2070-84 pubmed publisher
    ..KMUP-1 HCl in drinking water (2.5 mg/200 ml tap water) for 1-14 or 8-14 weeks decreased HFD-induced liver and body weight and scavenger receptor class B type I ..
  25. Yang Y, Li X, Xue Y, Zhang C, Wang Y, Hu X, et al. Bone marrow cells differentiation into organ cells using stem cell therapy. Eur Rev Med Pharmacol Sci. 2016;20:2899-907 pubmed
    ..Stem cell therapy (SCT) is progressing well in animal models, but the use of SCT in human remains to be explored further.
  26. Lanthier N, Lin Marq N, Rubbia Brandt L, Clement S, Goossens N, Spahr L. Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?. Stem Cell Res Ther. 2017;8:88 pubmed publisher
    Liver stem cell therapy (SCT) has been suggested as a promising means to improve liver regeneration in advanced liver disease. However, data from trials are heterogeneous, with no systematic histological evaluation...
  27. Maqbool F, Bahadar H, Niaz K, Baeeri M, Rahimifard M, Navaei Nigjeh M, et al. Effects of methyl mercury on the activity and gene expression of mouse Langerhans islets and glucose metabolism. Food Chem Toxicol. 2016;93:119-28 pubmed publisher
    ..MeHg was dissolved in tap water and administered at doses 2.5, 5 and 10 mg/kg/day, for 4 weeks...
  28. Dhodapkar M, Borrello I, Cohen A, Stadtmauer E. Hematologic Malignancies: Plasma Cell Disorders. Am Soc Clin Oncol Educ Book. 2017;37:561-568 pubmed publisher
    ..Infusion of CD19-targeted CAR T cells following salvage autologous stem cell transplantation (SCT) was safe and extended remission duration in a subset of patients with relapsed/refractory MM...
  29. Lee E, Kim D, Kim A, Lee E, Kim S, Lee M, et al. Chronic effects of losartan on the muscles and the serologic profiles of mdx mice. Life Sci. 2015;143:35-42 pubmed publisher
    ..Mdx mice, an animal model of Duchenne muscular dystrophy (DMD), were fed losartan dissolved in tap water. After 44weeks, the skeletal (gastrocnemius), cardiac, and diaphragm muscles of mdx mice were removed...
  30. Ehses S, Leonhardt R, Hansen G, Knittler M. Functional role of C-terminal sequence elements in the transporter associated with antigen processing. J Immunol. 2005;174:328-39 pubmed
    b>TAP delivers antigenic peptides into the endoplasmic reticulum (ER) that are subsequently bound by MHC class I molecules. TAP consists of two subunits (TAP1 and TAP2), each with a transmembrane (TMD) and a nucleotide-binding (NBD) domain...
  31. Ressing M, Keating S, van Leeuwen D, Koppers Lalic D, Pappworth I, Wiertz E, et al. Impaired transporter associated with antigen processing-dependent peptide transport during productive EBV infection. J Immunol. 2005;174:6829-38 pubmed
    ..Because steady-state levels of TAP proteins were unaffected, these results point toward EBV-induced interference with TAP function as a specific ..
  32. Raghavan M, Del Cid N, Rizvi S, Peters L. MHC class I assembly: out and about. Trends Immunol. 2008;29:436-43 pubmed publisher
    ..peptides is orchestrated by several assembly factors including the transporter associated with antigen processing (TAP) and tapasin, the endoplasmic reticulum (ER) oxido-reductases ERp57 and protein disulfide isomerase (PDI), the ..
  33. De Bleye C, Dumont E, Hubert C, Sacré P, Netchacovitch L, Chavez P, et al. A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering. Anal Chim Acta. 2015;888:118-25 pubmed publisher
    ..Raman scattering (SERS) method was developed for the sensitive detection of these molecules in spiked tap water solutions. Silver nanoparticles were used as SERS substrates...
  34. Salazar P, Martín M, González Mora J, González Elipe A. Application of Prussian Blue electrodes for amperometric detection of free chlorine in water samples using Flow Injection Analysis. Talanta. 2016;146:410-6 pubmed publisher
    ..3) and the limit of quantification (S/N=10) amounted to 8.25 and 24.6 ppb, respectively, adequate for controlling tap and drinking waters...
  35. Hale O, Cramer R. Collision-induced dissociation of doubly-charged barium-cationized lipids generated from liquid samples by atmospheric pressure matrix-assisted laser desorption/ionization provides structurally diagnostic product ions. Anal Bioanal Chem. 2018;410:1435-1444 pubmed publisher
    ..Pseudo-MS3 experiments such as in-source decay (ISD)-CID and ion mobility-enabled time-aligned parallel (TAP) MS of [snx+M-H]+ provided diagnostic product ion spectra for determining the location of double bonds ..
  36. Cai Z, Liu H. Microscopic and macroscopic approaches to the mental representations of second languages. Behav Brain Sci. 2017;40:e285 pubmed publisher
    With a particular reference to second language (L2), we discuss (1) how structural priming can be used to tap into L2 representations and their relationships with first and target language representations; and (2) how complex networks ..
  37. Gaudet R, Wiley D. Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. EMBO J. 2001;20:4964-72 pubmed
    The transporter associated with antigen processing (TAP) is an ABC transporter formed of two subunits, TAP1 and TAP2, each of which has an N-terminal membrane-spanning domain and a C-terminal ABC ATPase domain...
  38. Fujimoto Y, Kamakura A, Motohashi Y, Ohashi Kobayashi A, Maeda M. Transporter associated with antigen processing-like (ABCB9) stably expressed in Chinese hamster ovary-K1 cells is sorted to the microdomains of lysosomal membranes. Biol Pharm Bull. 2011;34:36-40 pubmed
    ..terminus of a human ATP-binding cassette (ABC) transporter, transporter associated with antigen processing (TAP)-like (TAPL), was tagged with green fluorescence protein (GFP), and the resulting fusion protein (TAPL-GFP) was ..
  39. Alzahrani Y, Aziz H, Shrestha N, Biscotti C, Singh A. Cryptococcal iridociliary granuloma. Surv Ophthalmol. 2016;61:498-501 pubmed publisher
    ..We describe a case of culture-positive cryptococcal iridociliary granuloma diagnosed by anterior chamber tap and fine-needle aspiration biopsy in a 60-year-old immunocompetent woman with acute granulomatous uveitis...
  40. Rashidi Nodeh H, Wan Ibrahim W, Ali I, Sanagi M. Development of magnetic graphene oxide adsorbent for the removal and preconcentration of As(III) and As(V) species from environmental water samples. Environ Sci Pollut Res Int. 2016;23:9759-73 pubmed publisher
    ..55-109.71 %) and good RSDs (0.1-4.3 %, n = 3) for spring water, lake, river, and tap water samples...
  41. Atalay K, Kirgiz A, Serefoglu Cabuk K, Erdogan Kaldirim H. Corneal topographic alterations after selective laser trabeculoplasty. Int Ophthalmol. 2017;37:905-910 pubmed publisher
    ..The Pretreatment Scheimpflug corneal topographic (SCT) findings were then compared with the post-treatment findings. The files of 33 patients were eligible...
  42. Ribeiro A, de Lacerda R, Correia D, Brunialti Godard A, de Miranda D, Campos V, et al. Possible involvement of ACSS2 gene in alcoholism. J Neural Transm (Vienna). 2017;124:1151-1158 pubmed publisher
    ..A fourth group had access only to tap water (control group)...
  43. Schmid B, Kesmir C, De Boer R. Quantifying how MHC polymorphism prevents pathogens from adapting to the antigen presentation pathway. Epidemics. 2010;2:99-108 pubmed publisher
    The classical antigen presentation pathway consists of two monomorphic (proteasome and TAP) and one polymorphic components (MHC Class I)...
  44. Lee S, Yahng S, Cho B, Eom K, Kim Y, Kim H, et al. Impact of pretransplant red cell transfusion on outcome after allogeneic stem cell transplantation in adult patients with severe aplastic anemia. Bone Marrow Transplant. 2016;51:1323-1329 pubmed publisher
    ..of pretransplant transfusion of packed red cells (PRCs) on outcome after allogeneic stem cell transplantation (SCT) in severe aplastic anemia (SAA). A total of 221 adult SAA patients receiving allogeneic SCT were analyzed...
  45. Poliakova T, Levin O, Arablinskiy A, Vasenina E, Zerr I. Cerebral microbleeds in early Alzheimer's disease. J Neurol. 2016;263:1961-8 pubmed publisher
    ..Cognitive Examination battery (CAMCOG) (Part 3), Clock Drawing Test, fluency test and the visual memory test (SCT)...
  46. Batyrova K, Hallenbeck P. Hydrogen Production by a Chlamydomonas reinhardtii Strain with Inducible Expression of Photosystem II. Int J Mol Sci. 2017;18: pubmed publisher
    ..it with the parental wild-type strain under photoheterotrophic conditions in regular tris-acetate-phosphate (TAP) medium with a 10-h:14-h light/dark regime...
  47. Levy G, Cordes M, Farivar A, Aye R, Louie B. Transversus Abdominis Plane Block Improves Perioperative Outcome After Esophagectomy Versus Epidural. Ann Thorac Surg. 2018;105:406-412 pubmed publisher
    ..A transversus abdominis plane (TAP) block has the potential to control upper abdominal pain without these adverse consequences...
  48. Trujillo Rodríguez M, Nan H, Anderson J. Expanding the use of polymeric ionic liquids in headspace solid-phase microextraction: Determination of ultraviolet filters in water samples. J Chromatogr A. 2018;1540:11-20 pubmed publisher
    ..5 to 15% were achieved. Finally, all proposed PIL-based fibers were applied towards the analysis of tap water, pool water and lake water, with the majority of the ultraviolet filters being detected and quantified in the ..
  49. Thammavongsa V, Schaefer M, Filzen T, Collins K, Carrington M, Bangia N, et al. Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503. Immunogenetics. 2009;61:703-16 pubmed publisher
    ..that can influence rates of ER-Golgi trafficking, binding to the transporter associated with antigen processing (TAP), tapasin dependence of assembly, and the efficiency and specificity of peptide binding...
  50. Yang X, Wang K, Wang H, Zhang J, Mao Z. Ethanol fermentation characteristics of recycled water by Saccharomyces cerevisiae in an integrated ethanol-methane fermentation process. Bioresour Technol. 2016;220:609-614 pubmed publisher
    ..Compared with tap water, fermentation time was shortened by 40% when mixed water was employed...
  51. Saqib M, Qi L, Hui P, Nsabimana A, Halawa M, Zhang W, et al. Development of luminol-N-hydroxyphthalimide chemiluminescence system for highly selective and sensitive detection of superoxide dismutase, uric acid and Co2. Biosens Bioelectron. 2018;99:519-524 pubmed publisher
    ..previously reported uric acid detection methods, and can detect uric acid in human urine and Co2+ in tap and lake water real samples with excellent recoveries in the range of 96.35-102.70%...
  52. Thabet Y, Walsh J, Breitkreutz J. Flexible and precise dosing of enalapril maleate for all paediatric age groups utilizing orodispersible minitablets. Int J Pharm. 2018;541:136-142 pubmed publisher
    ..025?mg EM. Although ODMTs were stable in the beverages over the investigated time period, dispersion in tap water only is recommended due to prolonged disintegration times within the other beverages...
  53. Yamaguchi Y, Iseoka H, Kobayashi A, Maeda M. The carboxyl terminal sequence of rat transporter associated with antigen processing (TAP)-like (ABCB9) is heterogeneous due to splicing of its mRNA. Biol Pharm Bull. 2004;27:100-4 pubmed
    Transporter associated with antigen processing (TAP)-like (TAPL) is a half-type ATP-binding cassette (ABC) transporter with sequence similarity to TAP1 and TAP2 and is highly conserved in mammals...
  54. Singal D, Ye M, Qiu X, D SOUZA M. Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis. Clin Exp Rheumatol. 1994;12:29-33 pubmed
    The human major histocompatibility complex (MHC) contains two closely related genes (TAP) that encode a family of transporter proteins. It is known that the TAP genes, like other MHC (class I and class II) genes, are polymorphic...
  55. Yan G, Shi L, Faustman D. Novel splicing of the human MHC-encoded peptide transporter confers unique properties. J Immunol. 1999;162:852-9 pubmed
    ..evaluated at multilevel in TAP1/2iso and TAP1/2 cotransfected T2 cells, a mutant cell line deplete of endogenous Tap gene products...
  56. Garcia Borges C, Phanavanh B, Crew M. Characterization of porcine TAP genes: alternative splicing of TAP1. Immunogenetics. 2006;58:374-82 pubmed
    The transporter associated with antigen processing (TAP) is a heterodimer composed of TAP1 and TAP2 subunits that belong to the ATP-binding cassette family of transporters...
  57. Benincá C, Vargas F, Martins M, Gonçalves F, Vargas R, Freire F, et al. Removal of clomazone herbicide from a synthetic effluent by electrocoagulation. Water Sci Technol. 2016;73:2944-52 pubmed publisher
    ..The aqueous solution (tap water + clomazone) with initial pH close to 7...
  58. Ocak M, Ak T, Aktaş A, Özbek N, Çağılcı O, Gümrükçüoğlu A, et al. Metal Complexation Properties of Schiff Bases Containing 1,3,5-Triazine Derived from 2-Hydroxy-1-Naphthaldehyde in Solution. A Simple Spectrofluorimetric Method to Determine Mercury (II). J Fluoresc. 2017;27:59-68 pubmed publisher
    ..No cleanup or enrichment of the tap water sample was required. A modified standard addition method was used to eliminate matrix effect...
  59. Harden K, Kretsch N, Mann F, Herzhoff K, Tackett J, Steinberg L, et al. Beyond dual systems: A genetically-informed, latent factor model of behavioral and self-report measures related to adolescent risk-taking. Dev Cogn Neurosci. 2017;25:221-234 pubmed publisher
    ..whether different measures commonly interpreted as indicators of the same psychological construct do, in fact, tap the same underlying dimension of individual differences...
  60. Nicolás Toledo L, Cervantes Rodríguez M, Cuevas Romero E, Corona Quintanilla D, Pérez Sánchez E, Zambrano E, et al. Hitting a triple in the non-alcoholic fatty liver disease field: sucrose intake in adulthood increases fat content in the female but not in the male rat offspring of dams fed a gestational low-protein diet. J Dev Orig Health Dis. 2017;:1-9 pubmed publisher
    ..and male offspring of mothers fed a Control (C) or low-protein diet (Restricted, R) were provided with either tap water or 5% sucrose for a period of 10 weeks...
  61. Braun I, Herold A, Rode M, Conti E, Izaurralde E. Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export. J Biol Chem. 2001;276:20536-43 pubmed
    Human TAP and its yeast orthologue Mex67p are members of the multigene family of NXF proteins...
  62. Santella A, Catena R, Kovacevic I, Shah P, Yu Z, Marquina Solis J, et al. WormGUIDES: an interactive single cell developmental atlas and tool for collaborative multidimensional data exploration. BMC Bioinformatics. 2015;16:189 pubmed publisher
    ..The identity of each cell can be queried with a tap, and community databases searched for available information about that cell...
  63. Rogers L, Fogleman A, Verhulst S, Bhugra M, Rao K, Malone J, et al. Refining Measurement of Social Cognitive Theory Factors Associated with Exercise Adherence in Head and Neck Cancer Patients. J Psychosoc Oncol. 2015;33:467-87 pubmed publisher
    Social cognitive theory (SCT) measures related to exercise adherence in head and neck cancer (HNCa) patients were developed...
  64. Kongtim P, Popat U, Jimenez A, Gaballa S, El Fakih R, Rondon G, et al. Treatment with Hypomethylating Agents before Allogeneic Stem Cell Transplant Improves Progression-Free Survival for Patients with Chronic Myelomonocytic Leukemia. Biol Blood Marrow Transplant. 2016;22:47-53 pubmed publisher
    ..and 36 with CMML progressed to acute myeloid leukemia) who received an allogeneic stem cell transplant (allo-SCT) at our institution between April 1991 and December 2013 to identify factors associated with improved survival and ..
  65. Engelmann I, Coiteux V, Heim A, Magro L, Dewilde A, Dulery R, et al. Severe Adenovirus Pneumonia Followed by Bacterial Septicaemia: Relevance of Co-Infections in Allogeneic Hematopoietic Stem Cell Transplantation. Infect Disord Drug Targets. 2016;16:69-76 pubmed
    Infections are one of the major complications after allogeneic stem cell transplantation (allo-SCT). Disseminated infections with human adenoviruses species A, B or C are associated with a lethality of 24 to 36 %...
  66. Wang Y, Ma L, Mao Y, Jiang X, Xia Y, Yu K, et al. Comammox in drinking water systems. Water Res. 2017;116:332-341 pubmed publisher
    ..four metagenome assembled genomes (MAGs) of comammox Nitrospira that were retrieved from metagenome datasets of tap water in Singapore (SG-bin1 and SG-bin2), Hainan province, China (HN-bin3) and Stanford, CA, USA (ST-bin4)...
  67. Lyu W, Jia H, Deng C, Saito K, Yamada S, Kato H. Zeolite-Containing Mixture Supplementation Ameliorated Dextran Sodium Sulfate-Induced Colitis in Mice by Suppressing the Inflammatory Bowel Disease Pathway and Improving Apoptosis in Colon Mucosa. Nutrients. 2017;9: pubmed publisher
    ..C57BL6 mice were given an AIN-93G basal diet or a 0.8% HY containing diet and sterilized tap water for 11 days. Colitis was then induced by 1.5% (w/v) DSS-containing water for 9 days...
  68. Lian L, Lv J, Wang X, Lou D. Magnetic solid-phase extraction of tetracyclines using ferrous oxide coated magnetic silica microspheres from water samples. J Chromatogr A. 2018;1534:1-9 pubmed publisher
    ..solid-phase extraction approach was proposed for extraction of potential residues of tetracyclines (TCs) in tap and river water samples, based on Fe3O4@SiO2@FeO magnetic nanocomposite...
  69. Androlewicz M. The role of tapasin in MHC class I antigen assembly. Immunol Res. 1999;20:79-88 pubmed
    ..that the putative role of tapasin as a bridging molecule between transporter associated with antigen presentation (TAP) and class I is only of minor importance in tapasin action, and tapasin' s major role appears to be as an active ..
  70. Koch J, Guntrum R, Heintke S, Kyritsis C, Tampe R. Functional dissection of the transmembrane domains of the transporter associated with antigen processing (TAP). J Biol Chem. 2004;279:10142-7 pubmed
    ..The heterodimeric TAP complex has unique N-terminal domains in addition to a 6 + 6-transmembrane segment core common to most ABC ..
  71. Castagna L, Boubdallah R, Furst S, Coso D, El Cheikh J, Faucher C, et al. Disease status is a more reliable predictive factor than histology in lymphoma patients after reduced-intensity conditioning regimen and allo-SCT. Bone Marrow Transplant. 2013;48:794-8 pubmed publisher
    ..This reinforces the need to administer more effective debulking treatments to lymphoma patients, for optimal benefit of allogeneic immune recognition of minimal residual disease, independently from lymphoma histology. ..
  72. Ding J, Shen X, Liu W, Covaci A, Yang F. Occurrence and risk assessment of organophosphate esters in drinking water from Eastern China. Sci Total Environ. 2015;538:959-65 pubmed publisher
    ..99, 4.50, 27.6, 59.2 and 192ng/L in the bottled, well, barreled, direct drinking and tap waters, respectively...
  73. Zhou R, Li T, Su Y, Ma T, Zhang L, Ren H. Oxidative removal of metronidazole from aqueous solution by thermally activated persulfate process: kinetics and mechanisms. Environ Sci Pollut Res Int. 2018;25:2466-2475 pubmed publisher
    ..In this study, the mechanism of MNZ degradation in aqueous solutions via thermally activated persulfate (TAP) process was established under different conditions...
  74. Roth J, Benvenisti H, Constantini S. Watertight Dural Closure in Pediatric Craniotomies-Is It Really Necessary?. World Neurosurg. 2018;114:e743-e746 pubmed publisher
    ..At 1 year, 7.7% had a radiologic PM but only 3% were noticed clinically. Overall, 3% needed a PM tap, and 15 patients (9%) underwent CSF diversion procedures. There were no infections...
  75. Svanborg S, Johansen A, Abrahamsen R, Skeie S. The composition and functional properties of whey protein concentrates produced from buttermilk are comparable with those of whey protein concentrates produced from skimmed milk. J Dairy Sci. 2015;98:5829-40 pubmed publisher
    ..The ultrafiltration and diafiltration was performed at 50°C using pasteurized tap water and a membrane with a 20-kDa cut-off to retain as little lactose as possible in the final WPC powders...
  76. Strong M, Laskow T, Nakhoul H, Blanchard E, Liu Y, Wang X, et al. Latent Expression of the Epstein-Barr Virus (EBV)-Encoded Major Histocompatibility Complex Class I TAP Inhibitor, BNLF2a, in EBV-Positive Gastric Carcinomas. J Virol. 2015;89:10110-4 pubmed publisher
    ..immune evasion properties to infected cells through inhibition of transporter associated with antigen processing (TAP)-mediated transport of antigen peptides...
  77. Lee S, Jeong W, Kannan K, Moon H. Occurrence and exposure assessment of organophosphate flame retardants (OPFRs) through the consumption of drinking water in Korea. Water Res. 2016;103:182-188 pubmed publisher
    ..In this study, 127 drinking water samples were collected from tap water, purified water (tap water that is passed through in-house filters) and bottled water from major cities in ..
  78. Furtwängler R, Schlotthauer U, Gärtner B, Graf N, Simon A. Nosocomial legionellosis and invasive aspergillosis in a child with T-lymphoblastic leukemia. Int J Hyg Environ Health. 2017;220:900-905 pubmed publisher
    ..exposed to waterborne pathogens despite terminal water filtration due to a technical device to release residual tap water from the hose after showering. A sodium chloride nose spray was found to be contaminated with the A...
  79. Gartlan K, Bommiasamy H, Paz K, Wilkinson A, Owen M, Reichenbach D, et al. A critical role for donor-derived IL-22 in cutaneous chronic GVHD. Am J Transplant. 2017;: pubmed publisher
    ..GVHD) is the major cause of nonrelapse morbidity and mortality after allogeneic stem cell transplantation (allo-SCT)...
  80. Ozbaş Gerçeker F, Bozman N, Gezici S, Pehlivan M, Yilmaz M, Pehlivan S, et al. Association of TAP1 and TAP2 gene polymorphisms with hematological malignancies. Asian Pac J Cancer Prev. 2013;14:5213-7 pubmed
    Transporter associated with antigen presenting (TAP) 1 and TAP2 genes are localized in the major histocompatability complex (MHC) class II region and form a heterodimer playing a key role in endogenous pathways for antigen presentation...
  81. Tamm L, Garner A, Loren R, Epstein J, Vaughn A, Ciesielski H, et al. Slow sluggish cognitive tempo symptoms are associated with poorer academic performance in children with ADHD. Psychiatry Res. 2016;242:251-259 pubmed publisher
    Sluggish cognitive tempo (SCT) symptoms may confer risk for academic impairment in attention-deficit/hyperactivity disorder (ADHD)...
  82. Poiré X, Labopin M, Maertens J, Yakoub Agha I, Blaise D, Ifrah N, et al. Allogeneic stem cell transplantation in adult patients with acute myeloid leukaemia and 17p abnormalities in first complete remission: a study from the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (. J Hematol Oncol. 2017;10:20 pubmed publisher
    ..prognosis due to high refractoriness to conventional chemotherapy, and allogeneic stem cell transplantation (allo-SCT) appears as the only potential curative option...
  83. Arthur R, Hoogenboom J, Green R, Taylor M, de Bruin K. An eye tracking study of bloodstain pattern analysts during pattern classification. Int J Legal Med. 2018;132:875-885 pubmed publisher
    ..Eye tracking data were collected for each AOI and combined with verbal statements made by analysts after the classification task to determine the critical range ..
  84. Nakahara Y, Ozaki K, Matsuura T. Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents. Diabetes. 2017;66:2868-2874 pubmed publisher
    ..rats injected with alloxan (type 1 diabetic model) and db/db mice (type 2 diabetic model) were given either tap water alone or tap water containing fluoride. A cariostatic effect of fluoride was evident in the diabetic animals...
  85. Waller S, Packman A, Hausner M. Comparison of biofilm cell quantification methods for drinking water distribution systems. J Microbiol Methods. 2018;144:8-21 pubmed publisher
    ..methods for drinking water distribution systems lies in advancing understanding of biofilm growth and control mechanisms that may lead to improved water quality during conveyance and at the tap for greater public health protection.
  86. Vijayakumar S, Rajakumar B. Theoretical investigations on the kinetics of Cl atom initiated reactions of series of 1-alkenes. Environ Sci Pollut Res Int. 2018;25:4387-4405 pubmed publisher
    ..Canonical variational transition state theory (CVT) with small curvature tunneling (SCT) and conventional transition state theory (CTST) in combination with MP2/6-31G(d,p), MP2/6-31G+(d,p), and MP2/6-311..
  87. O Rourke M, Schmidt E, Metry J, Majewski M. Delayed Respiratory Depression Secondary to Opioid Overdose After Multimodal Analgesia With Transversus Abdominis Plane Blocks in Postanesthesia Care Unit: A Case Report. A A Case Rep. 2017;: pubmed publisher
    ..open abdominal surgery often includes multimodal analgesia with thoracic epidural or transversus abdominis plane (TAP) block...
  88. Ahn K, Gruhler A, Galocha B, Jones T, Wiertz E, Ploegh H, et al. The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity. 1997;6:613-21 pubmed
    ..is impaired because of defective peptide translocation by transporters associated with antigen processing (TAP). Peptide transport is restored in HCMV mutants lacking US6...
  89. Singal D, Ye M, Bienzle D. Transfection of TAP 1 gene restores HLA class I expression in human small-cell lung carcinoma. Int J Cancer. 1998;75:112-6 pubmed
    ..results provide conclusive evidence for a role of TAP1 gene in class I expression and suggest that transfection of TAP genes may be useful to upregulate class I expression in tumor cells...
  90. Tanji T, Nishikori K, Shiraishi H, Maeda M, Ohashi Kobayashi A. Co-operative function and mutual stabilization of the half ATP-binding cassette transporters HAF-4 and HAF-9 in Caenorhabditis elegans. Biochem J. 2013;452:467-75 pubmed publisher
    ..ABC (ATP-binding-cassette) transporters that are highly homologous to the human lysosomal peptide transporter TAPL [TAP (transporter associated with antigen processing)-like; ABCB9]...
  91. Fischbach H, Döring M, Nikles D, Lehnert E, Baldauf C, Kalinke U, et al. Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets. Nat Commun. 2015;6:6199 pubmed publisher
    ..transported across the endoplasmic reticulum (ER) membrane by the transporter associated with antigen processing (TAP). In the ER lumen antigenic peptides are loaded onto MHC I, which is displayed on the cell surface...
  92. Glorennec P, Lucas J, Mercat A, Roudot A, Le Bot B. Environmental and dietary exposure of young children to inorganic trace elements. Environ Int. 2016;97:28-36 pubmed publisher
    ..exposure of children aged 3-6years, living in France, to As, Cd, Cr, Cu, Mn, Pb, Sb, Sr, and V present in diet, tap water, air, soil and floor dust in the years 2007-2009...