FBXO3

Summary

Gene Symbol: FBXO3
Description: F-box protein 3
Alias: FBA, FBX3, F-box only protein 3, F-box protein FBX3
Species: human

Top Publications

  1. pmc Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia
    Tunahan Cakir
    Department of Chemical Engineering, Bogazici University, 34342, Bebek, Istanbul, Turkey
    Theor Biol Med Model 4:48. 2007
  2. ncbi [Immunophenotypic features of acute myeloid leukemia with AML-1/ETO fusion gene]
    Jian Jun Zhang
    Flow Cytomertry Laboratory, Department of Laboratory Medical Examination, Guangdong Provincial People s Hospital, Guangzhou 510080, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:378-81. 2007
  3. pmc Horizontal transfer of a eukaryotic plastid-targeted protein gene to cyanobacteria
    Matthew B Rogers
    Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, BC, Canada
    BMC Biol 5:26. 2007
  4. pmc Differential expression of Haemophilus parasuis genes in response to iron restriction and cerebrospinal fluid
    Devon S Metcalf
    Department of Pathobiology, University of Guelph, Guelph, Ontario
    Can J Vet Res 71:181-8. 2007
  5. ncbi Characterization of recombinant fructose-1,6-bisphosphate aldolase from Methylococcus capsulatus Bath
    O N Rozova
    Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 75:892-8. 2010
  6. ncbi Fructose-1,6-bisphosphate aldolases in amitochondriate protists constitute a single protein subfamily with eubacterial relationships
    Lidya Sánchez
    The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Gene 295:51-9. 2002
  7. doi Effect of cement selection and finishing technique on marginal opening of cast gold inlays
    Charles V Farrell
    Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA 98225 4035, USA
    J Prosthet Dent 99:287-92. 2008
  8. ncbi [Reliability of fetal pulse oximetry for the detection of fetal acidosis]
    B Seelbach-Göbel
    Klinik fur Frauenheilkunde und Geburtshilfe, St Hedwig Perinatalzentrum, Krankenhaus der Barmherzigen Bruder, Lehrstuhl der Universität Regensburg, Schwerpunkt Geburtshilfe, Regensburg
    Z Geburtshilfe Neonatol 209:43-50. 2005
  9. pmc Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans
    James S McCarthy
    University of Western Australia, Department of Medicine, Fremantle Hospital, Fremantle, Western Australia, Australia
    Infect Immun 70:851-8. 2002
  10. ncbi Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type class I aldolase
    B Siebers
    Department of Microbiology, Universitat Essen, 45117 Essen, Germany
    J Biol Chem 276:28710-8. 2001

Detail Information

Publications150 found, 100 shown here

  1. pmc Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia
    Tunahan Cakir
    Department of Chemical Engineering, Bogazici University, 34342, Bebek, Istanbul, Turkey
    Theor Biol Med Model 4:48. 2007
    ..To simplify this task and make it more practicable, we undertook stoichiometric modeling of brain energy metabolism with the major aim of including the main interacting pathways in and between astrocytes and neurons...
  2. ncbi [Immunophenotypic features of acute myeloid leukemia with AML-1/ETO fusion gene]
    Jian Jun Zhang
    Flow Cytomertry Laboratory, Department of Laboratory Medical Examination, Guangdong Provincial People s Hospital, Guangzhou 510080, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:378-81. 2007
    AML-1/ETO fusion gene is the frequent genetic lesion described in FBA M(2) type acute myeloid leukemia (AML-M(2)) and is associated with a favourable prognosis...
  3. pmc Horizontal transfer of a eukaryotic plastid-targeted protein gene to cyanobacteria
    Matthew B Rogers
    Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, BC, Canada
    BMC Biol 5:26. 2007
    ..In particular, gene flow from eukaryotes to prokaryotes is rarely documented with strong support, which is unusual since prokaryotic genomes appear to readily accept foreign genes...
  4. pmc Differential expression of Haemophilus parasuis genes in response to iron restriction and cerebrospinal fluid
    Devon S Metcalf
    Department of Pathobiology, University of Guelph, Guelph, Ontario
    Can J Vet Res 71:181-8. 2007
    ..polymerase chain reaction, we found that homologues of genes encoding fructose bisphosphate aldolase (fba), adenylosuccinate synthetase (purA), 2',3'-cyclic nucleotide phosphodiesterase (cpdB), lipoprotein signal ..
  5. ncbi Characterization of recombinant fructose-1,6-bisphosphate aldolase from Methylococcus capsulatus Bath
    O N Rozova
    Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 75:892-8. 2010
    The gene fba from the thermotolerant obligate methanotroph Methylococcus capsulatus Bath was cloned and expressed in Escherichia coli BL21(DE3)...
  6. ncbi Fructose-1,6-bisphosphate aldolases in amitochondriate protists constitute a single protein subfamily with eubacterial relationships
    Lidya Sánchez
    The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Gene 295:51-9. 2002
    Sequences of putative fructose-1,6-bisphospate aldolases (FBA) in five amitochondriate unicellular eukaryotes, the diplomonads Giardia intestinalis (published earlier) and Spironucleus barkhanus, the pelobiont Mastigamoeba balamuthi,the ..
  7. doi Effect of cement selection and finishing technique on marginal opening of cast gold inlays
    Charles V Farrell
    Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA 98225 4035, USA
    J Prosthet Dent 99:287-92. 2008
    ..With increasing interest in using resin and resin-modified glass ionomer cements for this purpose, marginal adaptation with use of these newer cements must be assessed...
  8. ncbi [Reliability of fetal pulse oximetry for the detection of fetal acidosis]
    B Seelbach-Göbel
    Klinik fur Frauenheilkunde und Geburtshilfe, St Hedwig Perinatalzentrum, Krankenhaus der Barmherzigen Bruder, Lehrstuhl der Universität Regensburg, Schwerpunkt Geburtshilfe, Regensburg
    Z Geburtshilfe Neonatol 209:43-50. 2005
    ..In all cases fetal blood pH and base excess were determined repeatedly by fetal blood analysis (FBA)...
  9. pmc Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans
    James S McCarthy
    University of Western Australia, Department of Medicine, Fremantle Hospital, Fremantle, Western Australia, Australia
    Infect Immun 70:851-8. 2002
    ..an open reading frame of 363 amino acids encoding the glycolytic enzyme fructose 1,6 bisphosphate aldolase (Ov-fba-1)...
  10. ncbi Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type class I aldolase
    B Siebers
    Department of Microbiology, Universitat Essen, 45117 Essen, Germany
    J Biol Chem 276:28710-8. 2001
    ..For enzymatic studies the fba genes of T. tenax and P. furiosus were expressed in Escherichia coli...
  11. doi Heat pretreatment alleviates UV-B toxicity in the cyanobacterium Anabaena doliolum: A proteomic analysis of cross tolerance
    Yogesh Mishra
    Center of Advanced Study in Botany, Banaras Hindu University, Varanasi, India
    Photochem Photobiol 85:824-33. 2009
    ..phycobilisome core component (PBS-CC), iron superoxide dismutase (Fe-SOD), fructose-1,6-bisphosphate aldolase (FBA), nucleoside diphosphate kinase (NDPK), phosphoribulokinase (PRK) and ribulose-1,5-bisphosphate carboxylase/..
  12. doi Proteome-based physiological analysis of the metabolically engineered succinic acid producer Mannheimia succiniciproducens LPK7
    Jeong Wook Lee
    Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering BK21 Program, BioProcess Engineering Research Center, KAIST, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Bioprocess Biosyst Eng 33:97-107. 2010
    ..Ppa, SerS, ProS, Pnp, PotD, MalK, RbsB, and TbpA), pyruvate metabolism (AceF and Lpd), glycolysis (GapA, Pgk, Fba, and TpiA), and amino acid biosynthesis (Asd, DapA, DapD, Gdh, ArgD, and ArgG) varied significantly in the LPK7 ..
  13. ncbi Inhaled foreign bodies: management according to early or late presentation
    Sameh Ibrahim Sersar
    Cardiothoracic Surgery, Mansoura University, 35516, Egypt
    Eur J Cardiothorac Surg 28:369-74. 2005
    ..aspirated foreign body (AFB), to evaluate the factors associated with delayed diagnosis of foreign body aspiration (FBA) in children and to compare clinical, radiological and bronchoscopic findings in the patients with suspected FBA...
  14. ncbi Nuclear transfer protocol affects messenger RNA expression patterns in cloned bovine blastocysts
    C Wrenzycki
    Department of Biotechnology, Institut für Tierzucht und Tierverhalten FAL, Mariensee, 31535 Neustadt, Germany
    Biol Reprod 65:309-17. 2001
    ..In experiment 1, employing either FBA (fusion before activation) or AFS (fusion and activation simultaneously) to generate NT blastocysts, Hsp mRNAs were ..
  15. doi Foreign body aspiration in children: the value of diagnostic criteria
    Gursu Kiyan
    Marmara University School of Medicine, Department of Pediatric Surgery, Tophanelioglu cad 13 15, Altunizade Uskudar, 34662 Istanbul, Turkey
    Int J Pediatr Otorhinolaryngol 73:963-7. 2009
    Foreign body aspiration (FBA) is a serious problem in children. While bronchoscopy should be performed in all patients with aspiration; patients without aspiration should be carefully excluded to avoid an unnecessary bronchoscopy...
  16. ncbi The antigen receptor (NCCRP-1) on catfish and zebrafish nonspecific cytotoxic cells belongs to a new gene family characterized by an F-box-associated domain
    Liliana Jaso-Friedmann
    Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602 7386, USA
    J Mol Evol 54:386-95. 2002
    ..present in NCCRP-1) and an extremely conserved C-terminal region that has been termed the F-box-associated domain (FBA). The FBA is currently of unknown function...
  17. pmc Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli
    Osbaldo Resendis-Antonio
    Bioengineering Department, University of California San Diego, La Jolla, California, USA
    PLoS Comput Biol 3:1887-95. 2007
    ..Flux balance analysis (FBA) was performed, and the predicted active metabolic pathways agreed qualitatively with experimental observations...
  18. ncbi Inhaled foreign bodies: presentation, management and value of history and plain chest radiography in delayed presentation
    Sameh Ibrahim Sersar
    Department of Cardiothoracic Surgery, Faculty of Medicine, Mansoura University, 35516 Mansoura, Egypt
    Otolaryngol Head Neck Surg 134:92-9. 2006
    ..on the outcome of the procedure and to evaluate the factors associated with delayed diagnosis of FB aspiration (FBA) in children; and to compare clinical, radiologic and bronchoscopic findings in the patients with suspected FB ..
  19. pmc Modeling Lactococcus lactis using a genome-scale flux model
    Ana Paula Oliveira
    Fluxome Sciences A S, Søltofts Plads, Building 223, DK 2800 Kgs Lyngby, Denmark
    BMC Microbiol 5:39. 2005
    ..Flux balance analysis (FBA) and minimization of metabolic adjustment (MOMA) were used as modeling frameworks.
  20. pmc Recruitment of complement factor H-like protein 1 promotes intracellular invasion by group A streptococci
    Vinod Pandiripally
    Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City 66160, USA
    Infect Immun 71:7119-28. 2003
    ..b>Fba is an FHL-1 and FH binding protein expressed on the surface of the human pathogenic bacterium, Streptococcus ..
  21. doi Management strategies in foreign-body aspiration
    Paola Zaupa
    Department of Pediatric Surgery, Medical University of Graz, Austria, Europa paola zaupa meduni graz at
    Indian J Pediatr 76:157-61. 2009
    ..management algorithm to ensure effective teamwork in decreasing morbidity and mortality in pediatric Foreign-Body Aspirations (FBA). Furthermore, the role of flexible bronchoscopy when compared to rigid bronchoscopy in FBA was evaluated.
  22. pmc Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology
    Jacek Puchałka
    Synthetic and Systems Biology Group, Helmholtz Center for Infection Research HZI, Braunschweig, Germany
    PLoS Comput Biol 4:e1000210. 2008
    ..putida KT2440. Network reconstruction and flux balance analysis (FBA) enabled definition of the structure of the metabolic network, identification of knowledge gaps, and pin-pointing ..
  23. ncbi The effect of activation treatments on the development of reconstructed bovine oocytes
    P C Shen
    Department of Animal Science, National Pingtung University of Science and Technology, Pingtung 912, Taiwan, ROC
    Anim Reprod Sci 106:1-12. 2008
    ..05). Reconstructed oocytes activated 4h after fusion (fusion before activation, FBA) had a higher blastocyst rate than those oocytes activated immediately after electrofusion (fusion and activation ..
  24. ncbi A flow-batch analyzer with piston propulsion applied to automatic preparation of calibration solutions for Mn determination in mineral waters by ET AAS
    Luciano F Almeida
    Universidade Federal de Pernambuco, CCEN, Departamento de Quimica Fundamental, Brazil
    Talanta 73:906-12. 2007
    ..Flow-batch analyzers (FBA) have been successfully applied to implement analytical procedures, such as: titrations, sample pre-treatment, ..
  25. pmc The global repressor SugR controls expression of genes of glycolysis and of the L-lactate dehydrogenase LdhA in Corynebacterium glutamicum
    Verena Engels
    Institute of Biotechnology I, Research Center Juelich, Juelich, Germany
    J Bacteriol 190:8033-44. 2008
    ..regions of genes of the glycolytic enzymes 6-phosphofructokinase (pfkA), fructose-1,6-bisphosphate aldolase (fba), enolase (eno), pyruvate kinase (pyk), and NAD-dependent L-lactate dehydrogenase (ldhA)...
  26. pmc Plasmid-dependent methylotrophy in thermotolerant Bacillus methanolicus
    Trygve Brautaset
    Department of Biotechnology, Norwegian University of Science and Technology, N 7491 Trondheim SINTEF Applied Chemistry, SINTEF, N 7043 Trondheim, Norway
    J Bacteriol 186:1229-38. 2004
    ..ribulose-5-phosphate 3-epimerase; tkt, encoding transketolase; glpX, encoding fructose-1,6-bisphosphatase; and fba, encoding fructose-1,6-bisphosphate aldolase) with deduced roles in methanol assimilation via the ribulose ..
  27. pmc Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
    Scott D Pegan
    Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, IL 60607, USA
    J Mol Biol 386:1038-53. 2009
    ..tuberculosis. The class IIa fructose 1,6-bisphosphate aldolase (FBA) enzyme from M. tuberculosis (MtFBA) has been proposed as one such target since it is upregulated in latent TB...
  28. ncbi The heterodox nature of "Turban Pins" in foreign body aspiration; the central anatolian experience
    Melih Kaptanoglu
    Department of Thoracic Surgery, Cumhuriyet University, Sivas, Turkiye
    Int J Pediatr Otorhinolaryngol 71:553-8. 2007
    ..The aim of this study is to determine the age and sex distribution and the nature of aspirated foreign bodies (FBs). We also compared Turban Pins (TP) with other FBs and discussed the extracting techniques...
  29. doi The moonlighting protein fructose-1, 6-bisphosphate aldolase of Neisseria meningitidis: surface localization and role in host cell adhesion
    Sarfraz A Tunio
    Molecular Bacteriology and Immunology Group, Institute of Infection, Immunity and Inflammation, Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, UK
    Mol Microbiol 76:605-15. 2010
    Fructose-1, 6-bisphosphate aldolases (FBA) are cytoplasmic glycolytic enzymes, which despite lacking identifiable secretion signals, have also been found localized to the surface of several bacteria where they bind host molecules and ..
  30. ncbi Multivalent II [beta-D-Galp-(1-->4)-beta-D-GlcpNAc] and Talpha [beta-D-Galp-(1-->3)-alpha-D-GalpNAc] specific Moraceae family plant lectin from the seeds of Ficus bengalensis fruits
    Biswajit Singha
    Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India
    Carbohydr Res 342:1034-43. 2007
    ..bengalensis agglutinin (FBA)...
  31. doi Genetic modification of flux for flux prediction of mutants
    Quanyu Zhao
    Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, 680 4 Kawazu, Iizuka, Fukuoka, Japan
    Bioinformatics 25:1702-8. 2009
    ..Some algorithms including flux balance analysis (FBA) and minimization of metabolic adjustment (MOMA) predict a flux distribution from a stoichiometric matrix in the ..
  32. doi Kinetics independent spectrometric analysis using non-linear calibration modelling and exploitation of concentration gradients generated by a flow-batch system for albumin and total protein determination in blood serum
    Margarida C Souza
    Universidade Federal do Amazonas, Instituto de Ciências Exatas e Tecnologia, Brazil
    Talanta 82:1027-32. 2010
    ..It uses a non-linear calibration model that explores concentration gradients generated by a flow-batch analyser (FBA) for the samples, dye, and the single standard solution...
  33. ncbi Cyanophora paradoxa: nucleotide sequence and phylogeny of the nucleus encoded muroplast fructose-1,6-bisphosphate aldolase
    A A Nickol
    ZMBP, Pflanzenphysiologie, , Germany
    Z Naturforsch C 55:991-1003. 2000
    ..isolation of a clone encoding the nucleus-encoded muroplast class-II fructose-1,6-bisphosphate aldolase (class-II FBA). Its nucleotide sequence was determined...
  34. ncbi Comparing flux balance analysis to network expansion: producibility, sustainability and the scope of compounds
    Kai Kruse
    Theoretical Biophysics, Insitute for Biology, Humboldt University, Berlin, Germany
    Genome Inform 20:91-101. 2008
    ..The producibility of metabolites from available resources is investigated systematically using flux balance analysis (FBA) and network expansion...
  35. ncbi Laryngeal foreign body mistreated as recurrent laryngitis and croup for one year
    Sinan Atmaca
    Department of Otolaryngology, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey
    Turk J Pediatr 51:65-6. 2009
    Foreign body aspiration (FBA) is a common, dangerous problem among children of all ages...
  36. doi Sputum eosinophilia, airway hyperresponsiveness and airway narrowing in young adults with former asthma
    Johsuke Hara
    Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Ishikawa, Japan
    Allergol Int 57:211-7. 2008
    ..30-80% of outgrown asthma subjects develop symptoms again later in life. We investigated inflammation and function of lower airway in adolescents with former asthma...
  37. ncbi Late diagnosis of foreign body aspiration in children with chronic respiratory symptoms
    F Karakoc
    Division of Pediatric Pulmonology, Marmara University, Istanbul, Turkey
    Int J Pediatr Otorhinolaryngol 71:241-6. 2007
    ..Children with undiagnosed and retained foreign bodies (FBs) may present with persistent respiratory symptoms. Delayed diagnosis is an important problem in developing countries and several factors affect the delay...
  38. pmc Understanding the adaptive growth strategy of Lactobacillus plantarum by in silico optimisation
    Bas Teusink
    Top Institute Food and Nutrition WCFS, Wageningen, The Netherlands
    PLoS Comput Biol 5:e1000410. 2009
    ..Hence, previous attempts to use FBA to predict metabolic fluxes in Lactobacillus plantarum failed, as this lactic acid bacterium produces lactate, even ..
  39. ncbi Tracheobronchial foreign bodies in children: importance of accurate history and plain chest radiography in delayed presentation
    B Tokar
    Departments of Paediatric Surgery and Radiology, Osmangazi University Faculty of Medicine, Eskisehir, Turkey
    Clin Radiol 59:609-15. 2004
    To evaluate the factors associated with delayed diagnosis of foreign body aspiration (FBA) in children and to compare clinical, radiological and bronchoscopic findings in the patients with suspected FBA.
  40. ncbi Thin-section axial multidetector computed tomography and multiplanar reformatted imaging of children with suspected foreign-body aspiration: Is virtual bronchoscopy overemphasized?
    M Kocaoglu
    Department of Radiology, Gulhane Military Medical School, Etlik, Ankara, Turkey
    Acta Radiol 47:746-51. 2006
    ..computed tomography (MDCT)-assisted virtual bronchoscopy (VB) to axial MDCT and multiplanar reformatted (MPR) imaging with respect to conventional bronchoscopy in the evaluation of children with suspected foreign-body aspiration (FBA).
  41. ncbi The antibiotic streptomycin assessed in a battery of in vitro tests for reproductive toxicology
    K Lemeire
    EggCentris NV, Z 1 Researchpark 310, B 1731 Zellik, Belgium
    Toxicol In Vitro 21:1348-53. 2007
    ..The follicle bio-assay (FBA) is a multiparametric long-term follicle culture system mimicking ovarian function; in vitro fertilisation (IVF) of ..
  42. doi Flux balance analysis of Chlorella sp. FC2 IITG under photoautotrophic and heterotrophic growth conditions
    Muthusivaramapandian Muthuraj
    Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India
    Photosynth Res 118:167-79. 2013
    ..In the present study, flux balance analysis (FBA) was carried out for an indigenous isolate Chlorella sp...
  43. ncbi Two new radiological findings to improve the diagnosis of bronchial foreign-body aspiration in children
    Guido Girardi
    Pediatric Pulmonary Section, Department of Pediatrics, Exequiel Gonzales Cortes Children s Hospital, University of Chile, Santiago, Chile
    Pediatr Pulmonol 38:261-4. 2004
    ..in the same hemithorax, and aeration within an area of atelectasis) in children with foreign-body aspiration (FBA). We performed a retrospective review of clinical characteristics and chest X-ray films of 133 children with FBA...
  44. doi The methylotrophic Bacillus methanolicus MGA3 possesses two distinct fructose 1,6-bisphosphate aldolases
    Jessica Stolzenberger
    Faculty of Biology and CeBiTec, Bielefeld University, Bielefeld, Germany
    Microbiology 159:1770-81. 2013
    ..Fructose 1,6-bisphosphate aldolase (FBA), a key enzyme of glycolysis and gluconeogenesis, is encoded in the genome of B...
  45. ncbi Complementary identification of multiple flux distributions and multiple metabolic pathways
    Dong Yup Lee
    Metabolic and Biomolecular Engineering National Research Laboratory, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong, Yuseong Gu, Daejeon 305 701, Korea
    Metab Eng 7:182-200. 2005
    ..This approach judiciously integrates flux balance analysis (FBA) based on linear programming and the graph-theoretic method for determining reaction pathways...
  46. ncbi Microscopic quantification of bacterial invasion by a novel antibody-independent staining method
    Franziska Agerer
    Zentrum für Infektionsforschung, Universitat Wurzburg, Rontgenring 11, 97070 Wurzburg, Germany
    J Microbiol Methods 59:23-32. 2004
    ..We describe a novel fluorescence staining protocol, called FITC-biotin-avidin (FBA) staining, which allows the differentiation between extracellular and intracellular bacteria and is independent of ..
  47. pmc A Model of an Integrated Immune System Pathway in Homo sapiens and Its Interaction with Superantigen Producing Expression Regulatory Pathway in Staphylococcus aureus: Comparing Behavior of Pathogen Perturbed and Unperturbed Pathway
    Namrata Tomar
    Machine Intelligence Unit, Indian Statistical Institute, Kolkata, India
    PLoS ONE 8:e80918. 2013
    ..Moreover, we have developed a formalism under Flux Balance Analysis (FBA) for the optimization of conflicting objective functions...
  48. ncbi Synthesis and preclinical evaluation of a folic acid derivative labeled with 18F for PET imaging of folate receptor-positive tumors
    Andrea Bettio
    Department of Chemistry and Applied Biosciences of ETH, Center for Radiopharmaceutical Science of ETH, PSI, and USZ, Zurich, Switzerland
    J Nucl Med 47:1153-60. 2006
    Folic acid was linked regioselectively through its alpha- and gamma-carboxyl groups to 4-fluorobenzylamine (FBA), and the alpha- and gamma-FBA-folate regioisomers were evaluated for their ability to bind to folate receptor-positive cells...
  49. pmc Regulatory on/off minimization of metabolic flux changes after genetic perturbations
    Tomer Shlomi
    School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel
    Proc Natl Acad Sci U S A 102:7695-700. 2005
    ..are compared with previously suggested algorithms, minimization of metabolic adjustment, and flux balance analysis (FBA)...
  50. doi Structure-based design and synthesis of novel dual-target inhibitors against cyanobacterial fructose-1,6-bisphosphate aldolase and fructose-1,6-bisphosphatase
    Ding Li
    Key Laboratory of Pesticide and Chemical Biology CCNU, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China
    J Agric Food Chem 61:7453-61. 2013
    Cyanobacteria class II fructose-1,6-bisphoshate aldolase (Cy-FBA-II) and cyanobacteria fructose-1,6-bisphosphatase (Cy-FBPase) are two neighboring key regulatory enzymes in the Calvin cycle of the cyanobacteria photosynthesis system...
  51. pmc Plant F-box protein evolution is determined by lineage-specific timing of major gene family expansion waves
    Aura Navarro-Quezada
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Halle Saale, Germany
    PLoS ONE 8:e68672. 2013
    ..we asked whether the largest subfamily in Arabidopsis thaliana, which carries a C-terminal F-box associated domain (FBA proteins) shares evolutionary patterns and signatures of selection with other FBPs...
  52. pmc The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum
    William R Harcombe
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 9:e1003091. 2013
    The most powerful genome-scale framework to model metabolism, flux balance analysis (FBA), is an evolutionary optimality model...
  53. doi Segregated flux balance analysis constrained by population structure/function data: the case of PHA production by mixed microbial cultures
    F Pardelha
    REQUIMTE CQFB, Chemistry Department, FCT Universidade Nova de Lisboa, 2829 516 Caparica, Portugal
    Biotechnol Bioeng 110:2267-76. 2013
    In this study we developed a segregated flux balance analysis (FBA) method to calculate metabolic flux distributions of the individual populations present in a mixed microbial culture (MMC)...
  54. doi A flow-batch analyzer using a low cost aquarium pump for classification of citrus juice with respect to brand
    Sueny Kêlia Barbosa Freitas
    Departamento de Quimica, Universidade Federal da Paraiba, CCEN, CP 5093, 58051 970 João Pessoa PB, Brazil
    Talanta 107:45-8. 2013
    This paper proposes a novel flow-batch analyzer (FBA), which employs a compact, low-cost aquarium air pump as an alternative to a peristaltic pump...
  55. doi Optimization of the solid-phase synthesis of [18F] radiolabeled peptides for positron emission tomography
    Jason B White
    Department of Biomedical Engineering, University of California, Davis, USA
    Appl Radiat Isot 70:2720-9. 2012
    ..selected for solid-phase radiolabeling of the model peptide VQAAIDYING with 4-[(18)F]fluorobenzoic acid ([(18)F]FBA). A wide range of radiochemical yields (18.8 ± 1.5% to 41.2 ± 5...
  56. doi Questions About Behavioral Function (QABF): adaptation and validation of the Spanish version
    David Simó-Pinatella
    Ramon Llull University, C Cister, 34, 08022 Barcelona, Spain
    Res Dev Disabil 34:1248-55. 2013
    ..These behaviors become a challenge for the families and for professionals. Functional behavioral assessment (FBA) is a method used to identify variables that influence or maintain challenging behaviors (CB) and aid in the ..
  57. doi Perceived subject outcomes and impact on health-related quality of life associated with diet using the new Food Benefits Assessment (FBA) questionnaire: development and psychometric validation
    Denis Guyonnet
    Danone Research, RD 128, F 91767 Palaiseau Cedex, France
    Public Health Nutr 11:1163-72. 2008
    ..To assess the perceived outcomes associated with diet/food intake in the general adult population...
  58. doi A rational design approach for amino acid supplementation in hepatocyte culture
    Hong Yang
    Department of Chemical and Biochemical Engineering, Rutgers, State University of New Jersey, Piscataway, New Jersey 08854, USA
    Biotechnol Bioeng 103:1176-91. 2009
    ..Flux balance analysis (FBA) is used to determine an amino acid flux profile consistent with a desired output; this is used to design an amino ..
  59. ncbi Stainless steel crown aspiration during sedation in pediatric dentistry
    A Adewumi
    Department of Pediatric Dentistry, College of Dentistry, University of Florida, Gainesville, FL, USA
    Pediatr Dent 30:59-62. 2008
    Foreign body aspiration (FBA) causes death in more than 300 children every year in the United States. Morbidity and mortality are increased in children due to narrow airways and immature protective mechanisms...
  60. pmc An unusual cause of chronic cough. Foreign body aspiration
    Lisa L Willett
    Division of General Internal Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 0012, USA
    J Gen Intern Med 21:C1-3. 2006
    Foreign body aspiration (FBA) is a serious medical problem, causing thousands of deaths nationally each year. Clinical presentations range from acute suffocation and death to chronic and subtle respiratory symptoms...
  61. ncbi What is the diagnostic value of flexible bronchoscopy in the initial investigation of children with suspected foreign body aspiration?
    Christian A Righini
    University Hospital, ENT Department, CHU A Michallon, Service ORL, 38043 Grenoble, France
    Int J Pediatr Otorhinolaryngol 71:1383-90. 2007
    ..Many studies have described the manifestation of foreign body aspiration (FbA); however, only a few analyzed the role of flexible bronchoscopy in the diagnosis of FbA...
  62. doi Modelling osmotic stress by Flux Balance Analysis at the genomic scale
    Aline Metris
    Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK
    Int J Food Microbiol 152:123-8. 2012
    ..One way to make these models more mechanistic is to use systems biology methods such as Flux Balance Analysis (FBA). FBA consists of evaluating the possible fluxes through the metabolic reactions taking place in a cell...
  63. pmc Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model
    Sven H Hausner
    Department of Biomedical Engineering, University of California Davis, Davis, California 95616, USA
    Cancer Res 69:5843-50. 2009
    ..the feasibility of imaging alpha(v)beta(6) in vivo by positron emission tomography (PET) using the peptide [(18)F]FBA-A20FMDV2...
  64. doi Flux balance analysis: interrogating genome-scale metabolic networks
    Matthew A Oberhardt
    Department of Biomedical Engineering, University of Virginia, Charlottesville, USA
    Methods Mol Biol 500:61-80. 2009
    Flux balance analysis (FBA) is a computational method to analyze reconstructions of biochemical networks. FBA requires the formulation of a biochemical network in a precise mathematical framework called a stoichiometric matrix...
  65. doi Insights into metabolic efficiency from flux analysis
    Xuewen Chen
    Department of Plant Biology, Michigan State University, East Lansing, MI 48823, USA
    J Exp Bot 63:2343-51. 2012
    ..flux analysis (MFA) as well as the uses and limitations of efficiency in predictive flux balance analysis (FBA) are highlighted...
  66. doi Physical models implemented in the GEANT4-DNA extension of the GEANT-4 toolkit for calculating initial radiation damage at the molecular level
    C Villagrasa
    Institut de Radioprotection et de Surete Nucleaire, DRPH, SDE, LDRI, B P 17, 92262 Fontenay aux Roses, France
    Radiat Prot Dosimetry 143:214-8. 2011
    ..They are mostly based on the plane-wave Born approximation (first Born approximation, or FBA) for inelastic interactions and on semi-empirical models for energies where the FBA fails (at low energies)...
  67. pmc Hypoxic response of Mycobacterium tuberculosis studied by metabolic labeling and proteome analysis of cellular and extracellular proteins
    Ida Rosenkrands
    Department of TB Immunology, Statens Serum Institut, Copenhagen, Denmark
    J Bacteriol 184:3485-91. 2002
    ..In M. tuberculosis culture filtrates, two additional proteins, Rv0363c (Fba) and Rv2780 (Ald), were found in increased amounts under oxygen limitation...
  68. pmc The biomass objective function
    Adam M Feist
    GT Life Sciences, Inc, 10520 Wateridge Circle, San Diego, CA 92122, USA
    Curr Opin Microbiol 13:344-9. 2010
    Flux balance analysis (FBA) is a mathematical approach for analyzing the flow of metabolites through a metabolic network...
  69. ncbi Effect of sun-dried raisins on bile acid excretion, intestinal transit time, and fecal weight: a dose-response study
    Gene A Spiller
    Sphera Foundation, Los Altos, CA 94023, USA
    J Med Food 6:87-91. 2003
    ..doses of sun-dried raisins (SDR) on intestinal transit time (TT), fecal weight (FW), and fecal bile acids (FBA) was investigated in 16 healthy adults (6 men and 10 women)...
  70. ncbi Prediction of dynamic behavior of mutant strains from limited wild-type data
    Hyun Seob Song
    School of Chemical Engineering, Purdue University, 480 Stadium Mall Drive, West Lafayette, IN 47907 2100, USA
    Metab Eng 14:69-80. 2012
    ..of mutant strain behavior in the past have been based on steady state theories such as flux balance analysis (FBA), minimization of metabolic adjustment (MOMA), and regulatory on/off minimization (ROOM)...
  71. doi Scaphoid excision and 4-bone arthrodesis versus proximal row carpectomy: a comparison of contact biomechanics
    Peter Tang
    Trauma Training Center, Department of Orthopaedic Surgery, Columbia University Medical Center, New York, NY 10032, USA
    J Hand Surg Am 37:1861-7. 2012
    We compare scaphoid excision and 4-bone arthrodesis (FBA) with proximal row carpectomy (PRC) in terms of contact pressure, area, and location.
  72. ncbi [Bronchoscopic findings in children with prolonged respiratory symptoms]
    N Krifa
    Hôpital Farhat Hached, Service d ORL et de Chirurgie Cervico faciale, Sousse, Tunisie
    Rev Laryngol Otol Rhinol (Bord) 130:111-5. 2009
    ..of a foreign body (FB), in children with prolonged respiratory symptoms and no history of foreign body aspiration (FBA); to establish a study of these criteria and to compare the clinical, radiological and broncoscopic findings in ..
  73. ncbi Separate face and body selectivity on the fusiform gyrus
    Rebecca F Schwarzlose
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Neurosci 25:11055-9. 2005
    ..Our localizer scans identified a fusiform body area (FBA), a body-selective region reported recently by Peelen and Downing (2005) that is anatomically distinct from the ..
  74. pmc Energy balance for analysis of complex metabolic networks
    Daniel A Beard
    Department of Bioengineering, University of Washington, Seattle, Washington 98915, USA
    Biophys J 83:79-86. 2002
    ..Approaches, such as flux balance analysis (FBA), that account for the known stoichiometry of the reaction network while avoiding implementation of detailed ..
  75. ncbi [Contraception in adolescents--address on the occasion of the FBA 2002]
    S Anthuber
    Klinik und Poliklinik fur Frauenheilkunde und Geburtshilfe, Klinikum der Ludwig Maximilians Universität München Grosshadern, Munich
    Zentralbl Gynakol 125:480-3. 2003
    ....
  76. pmc Metabolic modelling of polyhydroxyalkanoate copolymers production by mixed microbial cultures
    João M L Dias
    REQUIMTE, Chemistry Department, FCT Universidade Nova de Lisboa, 2829 516 Caparica, Portugal
    BMC Syst Biol 2:59. 2008
    ..The oxidative phosphorylation efficiency was estimated from rate measurements, which in turn allowed the estimation of the theoretical yield coefficients...
  77. pmc Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis
    Hong Xin
    Department of Pediatrics, Louisiana State University Health Sciences Center and Research Institute for Children, Children s Hospital, New Orleans, LA 70118, USA
    Proc Natl Acad Sci U S A 105:13526-31. 2008
    ..of expression during human candidiasis and cell wall association and included: fructose-bisphosphate aldolase (Fba); methyltetrahydropteroyltriglutamate (Met6); hyphal wall protein-1 (Hwp1); enolase (Enol); glyceraldehyde-3-..
  78. pmc Differential producibility analysis (DPA) of transcriptomic data with metabolic networks: deconstructing the metabolic response of M. tuberculosis
    Bhushan K Bonde
    Microbial Sciences Division, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
    PLoS Comput Biol 7:e1002060. 2011
    ..The method utilizes Flux Balance Analysis (FBA) to identify the set of genes that affect the ability to produce each metabolite in the network...
  79. ncbi Visual perception and neural correlates of novel 'biological motion'
    John A Pyles
    Department of Cognitive Sciences, 3151 Social Sciences Plaza, University of California Irvine, Irvine, CA 92697 5100, USA
    Vision Res 47:2786-97. 2007
    ..Non-human animations fail to engage the human STSp, and neural responses in pITG, ITS and FFA/FBA are reduced only for the point-light versions...
  80. ncbi Activation of the carcinogens N-hydroxy-N-2-fluorenylbenzamide and N-hydroxy-N-2-fluorenylacetamide via deacylations and acetyl transfers by rat peritoneal serosa and liver
    C L Ritter
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis 55455
    Carcinogenesis 15:163-70. 1994
    Intraperitoneally administered N-hydroxy-N-2-fluorenylbenzamide (N-OH-2-FBA) and N-hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA) are carcinogenic for rat peritoneum...
  81. doi Coping with challenging behaviours of children with autism: effectiveness of brief training workshop for frontline staff in special education settings
    C Y M Ling
    Department of Psychology, The Chinese University of Hong Kong, Hong Kong, China
    J Intellect Disabil Res 56:258-69. 2012
    ..of three staff training elements: psychoeducation (PE) on autism, introduction of functional behavioural analysis (FBA) and emotional management (EM), on the reaction of challenging behaviours for frontline staff towards children with ..
  82. pmc Detection of genes encoding internalization-associated proteins in Streptococcus pyogenes isolates from patients with invasive diseases and asymptomatic carriers
    Lucilla Baldassarri
    Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Clin Microbiol 45:1284-7. 2007
    ..from patients with invasive infections or from asymptomatic carriers were examined for genes (prtF1, prtF2, and fba) coding for fibronectin-binding proteins to evaluate their involvement in the pathogenesis of different ..
  83. doi Increasing the on-task homework behavior of youth with behavior disorders using functional behavioral assessment
    Renee O Hawkins
    University of Cincinnati, OH, USA
    Behav Modif 32:840-59. 2008
    ..Functional behavioral assessment (FBA) procedures may be helpful for intervention planning; however, there has been limited research on use of FBA with ..
  84. ncbi [Ion-sensitive nanoemulsion-in situ gel system for ophthalmic delivery of flurbiprofen axetil]
    Jin qiu Shen
    China Pharmaceutical University, Nanjing 210009, China
    Yao Xue Xue Bao 45:120-5. 2010
    The aim of the study is to prepare flurbiprofen axetil nanoemulsion-in situ gel system (FBA/NE-ISG) and observe its ocular pharmacokinetics, rheological behavior, TEM images, irritation and cornea retention...
  85. doi Functional characterisation of the extrastriate body area based on the N1 ERP component
    John C Taylor
    Wales Institute of Cognitive Neuroscience, Bangor University, United Kingdom
    Brain Cogn 73:153-9. 2010
    ..between two body-selective regions identified with fMRI (extrastriate body area or EBA; fusiform body area or FBA) in order to better understand the source of a body-selective N1 ERP component...
  86. doi Visual learning shapes the processing of complex movement stimuli in the human brain
    Jan Jastorff
    Section for Computational Sensomotorics, Department of Cognitive Neurology, Hertie Institute of Clinical Brain Research and Center for Integrative Neurosciences, University Clinic Tübingen, Tubingen, Germany
    J Neurosci 29:14026-38. 2009
    ..2) Enhanced of fMRI-selective adaptation already present before training in biological motion-related areas (pSTS, FBA). (3) Changes covarying with task difficulty in frontal areas...
  87. doi Targeting multiple targets in Pseudomonas aeruginosa PAO1 using flux balance analysis of a reconstructed genome-scale metabolic network
    Deepak Perumal
    Advanced Design and Modeling Lab, Nanyang Technological University, Singapore
    J Drug Target 19:1-13. 2011
    Constraint-based flux balance analysis (FBA) is a powerful tool for predicting target genes that can be engineered by analyzing the redistribution of metabolic fluxes on specific gene modifications...
  88. doi fMRI-adaptation studies of viewpoint tuning in the extrastriate and fusiform body areas
    John C Taylor
    Wales Institute of Cognitive Neuroscience, School of Psychology, Bangor University, Bangor, United Kingdom
    J Neurophysiol 103:1467-77. 2010
    ..shown to be sensitive to visual depictions of the human body--the extrastriate and fusiform body areas (EBA and FBA). The BOLD response to sequentially presented pairs of bodies was treated as an index of view invariance...
  89. doi Changes in protein expression profiles between a low phytic acid rice ( Oryza sativa L. Ssp. japonica) line and its parental line: a proteomic and bioinformatic approach
    Kaveh Emami
    School of Biology, Institute for Research on Environment and Sustainability, Newcastle University, Newcastle upon Tyne NE17RU, United Kingdom
    J Agric Food Chem 58:6912-22. 2010
    ..Bioinformatic analyses revealed that triose phosphate isomerase (TPI) and fructose bisphosphatealdolase (FBA), two major differentially expressed proteins, are involved in myo-inositol metabolism...
  90. doi Seeded ND medical image segmentation by cellular automaton on GPU
    Claude Kauffmann
    Department of Medical Imaging, Notre Dame Hospital, CHUM, 1560 Sherbrooke East, Montreal, QC H2L 4M1, Canada
    Int J Comput Assist Radiol Surg 5:251-62. 2010
    ..in N-dimensional (ND) medical image datasets by computation of weighted distances using the Ford-Bellman algorithm (FBA)...
  91. doi Differential fluorescence quenching of fluorescent nucleic acid base analogues by native nucleic acid monophosphates
    Madhavan Narayanan
    Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA
    J Phys Chem B 114:5953-63. 2010
    ..mechanism has been hypothesized to be photoinduced electron transfer following selective excitation of the FBA, but hard evidence for this has been lacking...
  92. pmc Advanced stoichiometric analysis of metabolic networks of mammalian systems
    Mehmet A Orman
    Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Crit Rev Biomed Eng 39:511-34. 2011
    ..Metabolic flux analysis (MFA), flux balance analysis (FBA), and metabolic pathway analysis (MPA) are among the most popular tools in stoichiometric network analysis...
  93. pmc Horizontal transmission of Candida albicans and evidence of a vaccine response in mice colonized with the fungus
    Jim E Cutler
    Department of Pediatrics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
    PLoS ONE 6:e22030. 2011
    ..albicans GI tract colonization and serum antibodies on mouse vaccination responses to the peptide, Fba, derived from fructose bisphosphate aldolase which has cytosolic and cell wall distributions in the fungus...
  94. ncbi Searching for the neural mechanisms of feature-based attention in the primate brain
    Julio Martinez-Trujillo
    Cognitive Neurophysiology Laboratory, Department of Physiology, McGill University, Montreal, QC H3G1Y6, Canada
    Neuron 70:1025-8. 2011
    ..Desimone and another by Cohen and Maunsell, provide new insights into the mechanisms of feature-based attention (FBA)...
  95. doi Synthesis, biological activity and HPLC validation of 1,2,3,4-tetrahydroacridine derivatives as acetylcholinesterase inhibitors
    Paweł Szymański
    Medical University, Department of Pharmaceutical Chemistry and Drug Analyses, ul Muszyńskiego 1, 90 151 Lodz, Poland
    Eur J Med Chem 46:3250-7. 2011
    The synthesis and biochemical evaluation of new hybrids of tacrine (THA) and 4-fluorobenzoic acid (4-FBA) possessing activity towards acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition are presented...
  96. pmc Combined noninvasive imaging and modeling approaches reveal metabolic compartmentation in the barley endosperm
    Hardy Rolletschek
    Leibniz Institut für Pflanzengenetik und Kulturpflanzenforschung, 06466 Gatersleben, Germany
    Plant Cell 23:3041-54. 2011
    ..Region-specific metabolism in the endosperm was characterized by flux balance analysis (FBA) and metabolite profiling...
  97. pmc Evaluation of neglected idiopathic ctev managed by ligamentotaxis using jess: a long-term followup
    Ajai Singh
    Department of Orthopaedics, C S M Medical University, 2 59, Viram Khand, Gomti Nagar, 226010 Lucknow, India
    Adv Orthop 2011:218489. 2011
    ..The pre- and postcorrection difference in FBA was statistically significant. Conclusion...
  98. doi A tetrapyrrole-regulated ubiquitin ligase controls algal nuclear DNA replication
    Yuki Kobayashi
    Graduate School of Horticulture, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
    Nat Cell Biol 13:483-7. 2011
    ..Here we identify an F-box protein of SCF-type E3 ubiquitin ligase (Fbx3) in the red alga Cyanidioschyzon merolae, which inhibits CDKA by ubiquitylating the relevant cyclin and inducing ..
  99. ncbi Fluxviz - Cytoscape plug-in for visualization of flux distributions in networks
    Matthias König
    Institute of Biochemistry, Medical Faculty of the Humboldt University, Charite, Monbijoustr 2, 10117 Berlin, Germany
    Genome Inform 24:96-103. 2010
    Methods like FBA and kinetic modeling are widely used to calculate fluxes in metabolic networks...
  100. doi A flexible state-space approach for the modeling of metabolic networks I: development of mathematical methods
    Adam C Baughman
    Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Metab Eng 13:125-37. 2011
    ..mathematical advantages of our modeling representation in comparison with other commonly used techniques (MFA and FBA)...
  101. pmc Yeast dynamic metabolic flux measurement in nutrient-rich media by HPLC and accelerator mass spectrometry
    Benjamin J Stewart
    Lawrence Livermore National Laboratory, Center for Accelerator Mass Spectrometry, 7000 East Avenue P O Box 808, L 397 Livermore, California 94551, USA
    Anal Chem 82:9812-7. 2010
    ..Flux balance analysis (FBA) is a constraint-based approach to modeling metabolic fluxes, but its utility is limited by a lack of experimental ..

Research Grants59

  1. Clostridial genome-scale metabolic and regulatory model of differentiation
    RYAN SENGER; Fiscal Year: 2007
    ..in silico metabolic and regulatory models has ensued using genome-scale networks and flux balance analysis (FBA)...
  2. ORAL SPIROCHETES - MOLECULAR GENETICS ANALYSIS
    HOWARD KURAMITSU; Fiscal Year: 1993
    ..Likewise, the gene coding for the fibronectin-binding adhesin (FBA) will be isolated in lambda gtll clone banks...
  3. Nonablative AlloSCT in Refractory Autoimmune Disease
    Mitchell Cairo; Fiscal Year: 2003
    ..specific aims include: 1) to determine the toxicity of RI conditioning with fludarabine, busulfan and alemtuzumab (FBA) followed by AIIoSCT; 2) to quantitate percent mixed and complete donor chimerism following FBA and AIIoSCT + DLI; ..
  4. THE FnA D REGION OF TENASCIN C AND NEURONAL GROWTH
    Sally Meiners; Fiscal Year: 2005
    ..Neurites demonstrate a strong preference for fbA-D when they are given a choice at an interface...
  5. Novel Data Capture and Assessment Technology for Behavior Disorders
    RONALD OBERLEITNER; Fiscal Year: 2007
    ..evaluate a tool designed to support the collection of rich data for performing a Functional Behavior Assessment (FBA) in schools focusing specifically on children with autism...
  6. Integrated Modeling of Cardiac Metabolism and Transport
    DANIEL BEARD; Fiscal Year: 2007
    ..Further applications of the proposed integrated model include profiling physiological responses to several challenges, such as (1) exercise; (2) ischemia; and (3) myoglobin and adenylate kinase gene deletions. ..
  7. CANDIDA ALBICANS SURFACE ANTIGENS
    Jim Cutler; Fiscal Year: 2006
    ....
  8. Analysis of Large-Scale Biochemical Systems
    DANIEL BEARD; Fiscal Year: 2007
    ..thermodynamic-based constraints on biochemical fluxes and concentration to augment the flux-balance analysis (FBA) approach...
  9. MSM Multiscale Modeling of the Heart in Cardiovascular
    DANIEL BEARD; Fiscal Year: 2007
    ..abstract_text> ..
  10. The CB1 Cannabinoid Receptor Activation By Protein Molecular Dynamics Simulations
    Joong Youn Shim; Fiscal Year: 2007
    ....
  11. Integrated Modeling of Cardiac Metabolism and Transport
    Daniel A Beard; Fiscal Year: 2010
    ..In addition, our proposed tools for simulation of the pathophysiological operation of metabolic control mechanisms in heart disease may be used to guide clinical interventions aimed at modulation of cardiac energy metabolism. ..
  12. Mechanisms of Metabolic Dysfunction in Heart Disease
    Daniel A Beard; Fiscal Year: 2010
    ..These data will be used in Aim 2 for model development, parameterization, and validation. Development and application of tissue-level modeling and simulation tools are pursued in Aim 3. ..
  13. Integrated Modeling of Cardiac Metabolism and Transport
    DANIEL BEARD; Fiscal Year: 2009
    ..In addition, our proposed tools for simulation of the pathophysiological operation of metabolic control mechanisms in heart disease may be used to guide clinical interventions aimed at modulation of cardiac energy metabolism. ..
  14. Mechanisms of Metabolic Dysfunction in Heart Disease
    DANIEL BEARD; Fiscal Year: 2009
    ..These data will be used in Aim 2 for model development, parameterization, and validation. Development and application of tissue-level modeling and simulation tools are pursued in Aim 3. ..
  15. CANDIDA ALBICANS SURFACE ANTIGENS
    Jim Cutler; Fiscal Year: 1993
    ..Finally, we developed the techniques and tools to focus on this important host/C. albicans interaction and should be able to fulfill our intended goals...
  16. CANDIDA ALBICANS SURFACE ANTIGENS
    Jim Cutler; Fiscal Year: 1991
    ..Virulence of these mutants will be tested in mouse models of candidiasis to ascertain which antigens may be related to the ability to cause disease. Such antigens will be isolated from wild type strains and chemically characterized...
  17. CANDIDA ALBICANS SURFACE ANTIGENS
    Jim Cutler; Fiscal Year: 2001
    ..These studies should yield important insights into C. Albicans-host interactions. The results may become applied to prevention and, possibly, therapy of disseminated candidiasis. ..