FBLN5

Summary

Gene Symbol: FBLN5
Description: fibulin 5
Alias: ADCL2, ARCL1A, ARMD3, DANCE, EVEC, FIBL-5, HNARMD, UP50, fibulin-5, developmental arteries and neural crest EGF-like protein, testis tissue sperm-binding protein Li 75n, urine p50 protein
Species: human
Products:     FBLN5

Top Publications

  1. Stone E, Braun T, Russell S, Kuehn M, Lotery A, Moore P, et al. Missense variations in the fibulin 5 gene and age-related macular degeneration. N Engl J Med. 2004;351:346-53 pubmed
    ..Seven of the 402 patients with AMD had amino acid-altering sequence variations in the fibulin 5 gene, whereas none were observed among 429 control subjects (P<0.01)...
  2. Hu Q, Loeys B, Coucke P, De Paepe A, Mecham R, Choi J, et al. Fibulin-5 mutations: mechanisms of impaired elastic fiber formation in recessive cutis laxa. Hum Mol Genet. 2006;15:3379-86 pubmed
    ..These findings support the hypothesis that fibulin-5 is necessary for elastic fiber formation by facilitating the deposition of elastin onto a microfibrillar scaffold via direct molecular interactions...
  3. Nakamura T, Ruiz Lozano P, Lindner V, Yabe D, Taniwaki M, Furukawa Y, et al. DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries. J Biol Chem. 1999;274:22476-83 pubmed
    ..and characterized mouse, rat, and human cDNAs that encode a novel secreted protein of 448 amino acids named DANCE (developmental arteries and neural crest epidermal growth factor (EGF)-like)...
  4. Hirai M, Horiguchi M, Ohbayashi T, Kita T, Chien K, Nakamura T. Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly. EMBO J. 2007;26:3283-95 pubmed
    ..We have previously shown that developing arteries and neural crest EGF-like protein (DANCE) (also designated fibulin-5) is essential for elastogenesis by studying DANCE-deficient mice...
  5. Budatha M, Roshanravan S, Zheng Q, Weislander C, Chapman S, Davis E, et al. Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans. J Clin Invest. 2011;121:2048-59 pubmed publisher
    ..In contrast to fibulin-5 knockouts (Fbln5-/-), Fbln5RGE/RGE mice were able to form intact elastic fibers and did not exhibit POP...
  6. Kapetanopoulos A, Fresser F, Millonig G, Shaul Y, Baier G, Utermann G. Direct interaction of the extracellular matrix protein DANCE with apolipoprotein(a) mediated by the kringle IV-type 2 domain. Mol Genet Genomics. 2002;267:440-6 pubmed
    ..The extracellular matrix protein DANCE [developmental arteries and neural crest epidermal growth factor (EGF)-like] recently implicated in atherogenesis ..
  7. Nguyen A, Itoh S, Jeney V, Yanagisawa H, Fujimoto M, Ushio Fukai M, et al. Fibulin-5 is a novel binding protein for extracellular superoxide dismutase. Circ Res. 2004;95:1067-74 pubmed
    ..This interaction may represent a novel mechanism for controlling vascular redox state in the extracellular space in various cardiovascular diseases such as atherosclerosis and hypertension in which oxidative stress is increased. ..
  8. Claus S, Fischer J, Megarbane H, Megarbane A, Jobard F, Debret R, et al. A p.C217R mutation in fibulin-5 from cutis laxa patients is associated with incomplete extracellular matrix formation in a skin equivalent model. J Invest Dermatol. 2008;128:1442-50 pubmed publisher
    ..649T --> C; p.C217R) in the fibulin-5 gene (FBLN5), which was, to our knowledge, previously unreported...
  9. Kapustin A, Stepanova V, Aniol N, Cines D, Poliakov A, Yarovoi S, et al. Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated ?1-integrin-dependent cell migration. Biochem J. 2012;443:491-503 pubmed publisher
    ..uPA stimulates migration of wild-type MEFs (mouse embryonic fibroblasts) (Fbln5+/+ MEFs), but has no effect on fibulin-5-deficient (Fbln5-/-) MEFs...

More Information

Publications104 found, 100 shown here

  1. Yanagisawa H, Davis E, Starcher B, Ouchi T, Yanagisawa M, Richardson J, et al. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature. 2002;415:168-71 pubmed
    ..The molecules and mechanisms involved in this process are unknown. Fibulin-5 (also known as EVEC/DANCE) is an extracellular matrix protein abundantly expressed in great vessels and cardiac valves during embryogenesis, ..
  2. Loeys B, Van Maldergem L, Mortier G, Coucke P, Gerniers S, Naeyaert J, et al. Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa. Hum Mol Genet. 2002;11:2113-8 pubmed
    ..As such, we provide evidence that a genetic defect in fibulin-5 (FBLN5, also known as EVEC or DANCE) is responsible for a recessive form of cutis laxa in humans.
  3. Markova D, Zou Y, Ringpfeil F, Sasaki T, Kostka G, Timpl R, et al. Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene. Am J Hum Genet. 2003;72:998-1004 pubmed
    ..The results demonstrate that a heterozygous mutation in fibulin-5 can cause cutis laxa and also suggest that fibulin-5 and elastin gene mutations are not the exclusive cause of the disease. ..
  4. Hu Q, Reymond J, Pinel N, Zabot M, Urban Z. Inflammatory destruction of elastic fibers in acquired cutis laxa is associated with missense alleles in the elastin and fibulin-5 genes. J Invest Dermatol. 2006;126:283-90 pubmed
    ..Mutational analysis showed that the patient was heterozygous for an inherited fibulin-5 (FBLN5) allele G202R and compound heterozygous for elastin (ELN) alleles A55V and G773D...
  5. Lomas A, Mellody K, Freeman L, Bax D, Shuttleworth C, Kielty C. Fibulin-5 binds human smooth-muscle cells through alpha5beta1 and alpha4beta1 integrins, but does not support receptor activation. Biochem J. 2007;405:417-28 pubmed
    ..We have thus identified the beta1 integrins on primary SMCs that fibulin-5 interacts with, and have shown that failure of fibulin-5 to activate these receptors limits cell spreading, migration and proliferation. ..
  6. Nonaka R, Onoue S, Wachi H, Sato F, Urban Z, Starcher B, et al. DANCE/fibulin-5 promotes elastic fiber formation in a tropoelastin isoform-dependent manner. Clin Biochem. 2009;42:713-21 pubmed publisher
    ..These data provide new insights into the initial steps of elastic fiber assembly and identify fibulin-5 and tropoelastin isoforms as potential targets for the regeneration of elastic fibers in vivo. ..
  7. Hu Z, Ai Q, Xu H, Ma X, Li H, Shi T, et al. Fibulin-5 is down-regulated in urothelial carcinoma of bladder and inhibits growth and invasion of human bladder cancer cell line 5637. Urol Oncol. 2011;29:430-5 pubmed publisher
    ..Fibulin-5 is down-regulated in urothelial carcinoma of bladder and acts as a tumor suppressor gene by inhibiting proliferation and invasion of bladder cancer cells. ..
  8. Zhou S, Xiao W, Wan Q, Yi C, Xiao F, Liu Y, et al. Nogo-B mediates HeLa cell adhesion and motility through binding of Fibulin-5. Biochem Biophys Res Commun. 2010;398:247-53 pubmed publisher
    ..Thus, identification of the Nogo-B binding protein Fibulin-5 may contribute to uncover the pathway in which Nogo-B regulates tumor cell movement. ..
  9. Nakamura T, Lozano P, Ikeda Y, Iwanaga Y, Hinek A, Minamisawa S, et al. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature. 2002;415:171-5 pubmed
    ..Here we report that fibulin-5 (also known as DANCE), a recently discovered integrin ligand, is an essential determinant of elastic fibre organization...
  10. Freeman L, Lomas A, Hodson N, Sherratt M, Mellody K, Weiss A, et al. Fibulin-5 interacts with fibrillin-1 molecules and microfibrils. Biochem J. 2005;388:1-5 pubmed
    ..Fibulin-5 may provide a link between tropoelastin and microfibrils in the pericellular space during elastic fibre assembly...
  11. El Hallous E, Sasaki T, Hubmacher D, Getie M, Tiedemann K, Brinckmann J, et al. Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin. J Biol Chem. 2007;282:8935-46 pubmed
    ..Formation of ternary complexes between fibrillin-1, fibulins, and tropoelastin demonstrated that fibulin-2 and -5 but much less fibulin-4, are able to act as molecular adaptors between fibrillin-1 and tropoelastin. ..
  12. Guadall A, Orriols M, Rodríguez Calvo R, Calvayrac O, Crespo J, Aledo R, et al. Fibulin-5 is up-regulated by hypoxia in endothelial cells through a hypoxia-inducible factor-1 (HIF-1?)-dependent mechanism. J Biol Chem. 2011;286:7093-103 pubmed publisher
    Hypoxia modulates gene expression and affects multiple aspects of endothelial cell biology. Fibulin-5 (FBLN5) is an extracellular matrix protein essential for elastic fiber assembly and vasculogenesis that participates in vascular ..
  13. Møller H, Ralfkjær U, Cremers N, Frankel M, Pedersen R, Klingelhofer J, et al. Role of fibulin-5 in metastatic organ colonization. Mol Cancer Res. 2011;9:553-63 pubmed publisher
    ..in response to tumor-conditioned medium, whereas expression of cadherin-16 (Cdh16), Ccn2, and fibulin-5 (Fbln5) was downregulated...
  14. Hwang C, Shiu L, Su L, Yu Fang Yin -, Wang W, Huang S, et al. Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis. PLoS ONE. 2013;8:e84218 pubmed publisher
    ..Higher fibulin-5 expression is not only an important indicator of poor survival, but also contributes to the development of new therapeutic strategies in the FLJ10540/AKT pathway for NPC treatment. ..
  15. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer J, et al. Elastic fiber homeostasis requires lysyl oxidase-like 1 protein. Nat Genet. 2004;36:178-82 pubmed
    ..Thus elastin polymer deposition is a crucial aspect of elastic fiber maintenance and is dependent on LOXL1, which serves both as a cross-linking enzyme and an element of the scaffold to ensure spatially defined deposition of elastin...
  16. Hirai M, Ohbayashi T, Horiguchi M, Okawa K, Hagiwara A, Chien K, et al. Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. J Cell Biol. 2007;176:1061-71 pubmed
    ..We and others previously showed that fibulin-5 (also called developing arteries and neural crest EGF-like [DANCE] or embryonic vascular EGF-like repeat-containing protein [EVEC]) is indispensable for elastogenesis by studying ..
  17. Duz M, Kirat E, Coucke P, Koparir E, Gezdirici A, Paepe A, et al. A novel case of autosomal dominant cutis laxa in a consanguineous family: report and literature review. Clin Dysmorphol. 2017;26:142-147 pubmed publisher
    ..exons of the ELN gene (ADCL1, OMIM #123700), whereas one patient was described to have a tandem duplication in the FBLN5 gene (ADCL2, OMIM #614434)...
  18. Papke C, Tsunezumi J, Ringuette L, Nagaoka H, Terajima M, Yamashiro Y, et al. Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutations. Hum Mol Genet. 2015;24:5867-79 pubmed publisher
    Homozygous recessive mutations in either EFEMP2 (encoding fibulin-4) or FBLN5 (encoding fibulin-5), critical genes for elastogenesis, lead to autosomal recessive cutis laxa types 1B and 1A, respectively...
  19. Harris S. Psychogenic movement disorders in children and adolescents: an update. Eur J Pediatr. 2019;178:581-585 pubmed publisher
    ..school-related problems, medical illness/surgery, sleep disturbance, and participation in competitive sport or dance. The most frequently mentioned treatments were cognitive behavioral therapy, psychotherapy, relaxation techniques, ..
  20. Song Y, Chen J, Cai F, Lu Y, Chen Q, Zhang Y, et al. A metabolic mechanism analysis of Fuzheng-Huayu formula for improving liver cirrhosis with traditional Chinese medicine syndromes. Acta Pharmacol Sin. 2017;: pubmed publisher
    ..into 5 TCM syndrome groups including the liver stagnation syndrome (LSS), spleen deficiency and damp overabun¬dance syndrome (SDDOS), damp-heat accumulation syndrome (DHAS), liver-kidney Yin deficiency syndrome (LKYDS), and blood ..
  21. Cahalan R, Bargary N, O Sullivan K. Pain and Injury in Elite Adolescent Irish Dancers: A Cross-Sectional Study. J Dance Med Sci. 2018;22:91-99 pubmed publisher
    b>Dance is an extremely popular activity among adolescents and has a range of associated physical and psychological health benefits...
  22. Fowler K, Mandawala A, Griffin D. The role of chromosome segregation and nuclear organisation in human subfertility. Biochem Soc Trans. 2019;47:425-432 pubmed publisher
    ..Faithful chromosome segregation is thus crucial, as is an ordered spatio-temporal 'dance' of packing a large amount of chromatin into a very small space...
  23. Lanska D. The Dancing Manias: Psychogenic Illness as a Social Phenomenon. Front Neurol Neurosci. 2018;42:132-141 pubmed publisher
    ..The term "dancing mania" was derived from "choreomania," a concatenation of choros (dance) and mania (madness)...
  24. Muimo R, Alothaid H, Mehta A. NM23 proteins: innocent bystanders or local energy boosters for CFTR?. Lab Invest. 2018;98:272-282 pubmed publisher
    ..Furthermore, its multiple partners make CFTR dance to different tunes in different cellular and subcellular locations as it recycles from the plasma membrane to ..
  25. Kroon A, Wang J, Post M. Alterations in expression of elastogenic and angiogenic genes by different conditions of mechanical ventilation in newborn rat lung. Am J Physiol Lung Cell Mol Physiol. 2015;308:L639-49 pubmed publisher
    ..on expression of genes involved in alveolarization [tropoelastin (Eln), lysyloxidase-like 1 (Loxl1), fibulin5 (Fbln5), and tenascin-C (Tnc)] and angiogenesis [platelet derived growth factors (Pdgf) and vascular endothelial growth ..
  26. Loprinzi P, Sng E. Mode-specific physical activity and leukocyte telomere length among U.S. adults: Implications of running on cellular aging. Prev Med. 2016;85:17-9 pubmed publisher
    ..98%; n=193), basketball (2.0%; n=129), bicycling (3.71%; n=240), dance (2.30%; n=149), running (3.09%; n=200), stair climbing (1.33%, n=86), swimming (1.85%, n=120), walking (13...
  27. Zhao B, Zhou J. Decreased expression of elastin, fibulin-5 and lysyl oxidase-like 1 in the uterosacral ligaments of postmenopausal women with pelvic organ prolapse. J Obstet Gynaecol Res. 2012;38:925-31 pubmed publisher
  28. Hackney J, Brummel S, Newman M, Scott S, Reinagel M, Smith J. Effect of Reduced Stiffness Dance Flooring on Lower Extremity Joint Angular Trajectories During a Ballet Jump. J Dance Med Sci. 2015;19:110-7 pubmed publisher
    ..It was hypothesized that performing a ballet jump (sauté) on a reduced stiffness dance floor would decrease maximum joint flexion angles and negative angular velocities at the hips, knees, or ankles ..
  29. Butler M, Snook B, Buck R. The Transformative Potential of Community Dance for People With Cancer. Qual Health Res. 2016;26:1928-1938 pubmed
    This research describes a community dance project for people affected by cancer, which was led by a trained community dancer over 10 movement workshops and three performances...
  30. Claus A, Macdonald D. Interpreting Pain Symptoms and How Pain Affects Neuromuscular Control in Dancers: If I'm in Pain, How Should I Train?. J Dance Med Sci. 2017;21:5-12 pubmed publisher
    ..control of posture and movement to help inform rehabilitation approaches and when it may or may not be prudent to "dance through" pain...
  31. Levin K. The Dance of Attention: Toward an Aesthetic Dimension of Attention-Deficit. Integr Psychol Behav Sci. 2018;52:129-151 pubmed publisher
  32. Lippi S, Petit L. Subverting Space: An Exploration of a Dance Therapy Workshop Apparatus for Schizophrenics. Psychoanal Rev. 2017;104:231-252 pubmed publisher
    The authors created a dance workshop for schizophrenic patients designed to address their singular experience of space, in which the categories of interior and exterior do not function as limits...
  33. Van de Winckel A, Tseng Y, Chantigian D, Lorant K, Zarandi Z, Buchanan J, et al. Age-Related Decline of Wrist Position Sense and its Relationship to Specific Physical Training. Front Hum Neurosci. 2017;11:570 pubmed publisher
    ..Current levels of physical activity and previous sport, musical, or dance training were obtained through a questionnaire...
  34. Rietveld A, Hagemans F. Operative Treatment of Posterior Ankle Impingement Syndrome and Flexor Hallucis Longus Tendinopathy in Dancers Open Versus Endoscopic Approach. J Dance Med Sci. 2018;22:11-18 pubmed publisher
    ..files, clinical evaluation, American Orthopaedic Foot and Ankle Society (AOFAS) scoring, and we administered a dance-specific questionnaire...
  35. Timmers J, Voorde M, Engen R, Landsveld Verhoeven C, Pijnappel R, Greve K, et al. Mammography with and without radiolucent positioning sheets: Comparison of projected breast area, pain experience, radiation dose and technical image quality. Eur J Radiol. 2015;84:1903-9 pubmed publisher
    ..Pain was scored using the Numeric Rating Scale. Radiation dose was estimated using the Dance model and projected breast area using computer software...
  36. Saffran L. What Pauline Doesn't Know: Using Guided Fiction Writing to Educate Health Professionals about Cultural Competence. J Med Humanit. 2018;39:275-283 pubmed publisher
    ..Through an analysis of the short story "Pie Dance" by Molly Giles, juxtaposed with descriptions of specific writing exercises, this paper explains how the demands ..
  37. Policarpo Barbosa F, Valdivia Moral P, Medeiros do Nascimento M, Fernandes Filho J. [Effects of physical activity on women's morphology]. Rev Salud Publica (Bogota). 2016;18:404-411 pubmed publisher
    ..volunteers, aged between 42 and 56 years and divided into groups: G1 (n=15, recreational activities) and G2 (n=13, dance activities)...
  38. Mohr A, Friscia M, Yeakel J, Logan B. Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees. Forensic Sci Int. 2018;282:168-178 pubmed publisher
    ..of their physical and mind-altering properties, NPS may be deliberately or inadvertently ingested at electronic dance music (EDM) festivals to enhance the attendees' appreciation of the music and overall experience...
  39. Bachrach A, Jola C, Pallier C. Neuronal bases of structural coherence in contemporary dance observation. Neuroimage. 2016;124:464-472 pubmed publisher
    The neuronal processes underlying dance observation have been the focus of an increasing number of brain imaging studies over the past decade...
  40. Vicary S, Sperling M, von Zimmermann J, Richardson D, Orgs G. Joint action aesthetics. PLoS ONE. 2017;12:e0180101 pubmed publisher
    Synchronized movement is a ubiquitous feature of dance and music performance. Much research into the evolutionary origins of these cultural practices has focused on why humans perform rather than watch or listen to dance and music...
  41. Gennaro G, Bernardi D, Houssami N. Radiation dose with digital breast tomosynthesis compared to digital mammography: per-view analysis. Eur Radiol. 2018;28:573-581 pubmed publisher
    ..density (VBD) and were used together with exposure data to compute the mean glandular dose (MGD) according to Dance's model. DBT and FFDM were compared in terms of operation of the automatic exposure control (AEC) and MGD level...
  42. Chen J, Tran C, Hwang L, Deng G, Jung M, Faull K, et al. Partial Amelioration of Peripheral and Central Symptoms of Huntington's Disease via Modulation of Lipid Metabolism. J Huntingtons Dis. 2016;5:65-81 pubmed publisher
    Huntington's disease (HD) is a fatal, inherited neurodegenerative disorder characterized by uncontrollable dance-like movements, as well as cognitive deficits and mood changes...
  43. Su Y, Keller P. Your move or mine? Music training and kinematic compatibility modulate synchronization with self- versus other-generated dance movement. Psychol Res. 2018;: pubmed publisher
    ..Here, we investigated whether similar mechanisms govern a related form of rhythmic action: dance. We examined (1) whether synchronization with visual dance stimuli was influenced by movement agency, (2) whether ..
  44. Joshi H, Gosselink M, Smyth E, Hompes R, Cunningham C, Lindsey I, et al. Expression of fibulin-5 in the skin of patients with rectal prolapse. Colorectal Dis. 2015;17:996-1001 pubmed publisher
    ..the pelvic floor has been demonstrated in transgenic mice, with animals which have a null mutation in fibulin-5 (Fbln5(i/i)) developing prolapse...
  45. Namiki S, Kanzaki R. The neurobiological basis of orientation in insects: insights from the silkmoth mating dance. Curr Opin Insect Sci. 2016;15:16-26 pubmed publisher
    ..We hypothesize that this zigzag module is utilized in a wide range of insect behavior. We introduce two examples of the potential use: orientation flight and the waggle dance in bees.
  46. Chantall Rocha S, Japyassú H. Diffuse resistance courtship in the scorpion Rhopalurus rochai (Scorpiones: Buthidae). Behav Processes. 2017;135:45-55 pubmed publisher
    ..The screening for prospective partners occurs in the pre-dance phase...
  47. Steinberg N, Tenenbaum S, Hershkovitz I, Zeev A, Siev Ner I. Lower extremity and spine characteristics in young dancers with and without patellofemoral pain. Res Sports Med. 2017;25:166-180 pubmed publisher
    ..All dancers were screened for morphometric profile, dance discipline (h/week), anatomical anomalies (present/absent of scoliosis, genu valgus/varum, etc...
  48. Tafiadis D, Kosma E, Chronopoulos S, Papadopoulos A, Toki E, Vassiliki S, et al. Acoustic and Perceived Measurements Certifying Tango as Voice Treatment Method. J Voice. 2018;32:256.e13-256.e24 pubmed publisher
    ..Voice Handicap Index and Voice Evaluation Form), and their voices were recorded before and after the tango dance session. Moreover, water consumption was investigated...
  49. Mak M, Wong Yu I, Shen X, Chung C. Long-term effects of exercise and physical therapy in people with Parkinson disease. Nat Rev Neurol. 2017;13:689-703 pubmed publisher
    ..Sustained strength training, aerobic training, tai chi or dance therapy lasting at least 12 weeks can produce long-term beneficial effects...
  50. Laland K, Wilkins C, Clayton N. The evolution of dance. Curr Biol. 2016;26:R5-9 pubmed publisher
    Evidence from multiple sources reveals a surprising link between imitation and dance. As in the classical correspondence problem central to imitation research, dance requires mapping across sensory modalities and the integration of ..
  51. Okuyama T, Shirakawa J, Yanagisawa H, Kyohara M, Yamazaki S, Tajima K, et al. Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets. Sci Rep. 2017;7:2364 pubmed publisher
    ..glucokinase activation using a glucokinase activator (GKA) significantly upregulated the expression of Fibulin-5 (Fbln5), a matricellular protein involved in matrix-cell signaling, in isolated mouse islets...
  52. Bennett A, Lavie C, Grace S. Cardiac Rehabilitation Following Acute Coronary Syndrome in Women. Curr Treat Options Cardiovasc Med. 2017;19:57 pubmed publisher
    ..g., offering dance, opportunities for social interaction), and offering non-supervised delivery models...
  53. Hanna G, Noelker L, Bienvenu B. The arts, health, and aging in america: 2005-2015. Gerontologist. 2015;55:271-7 pubmed publisher
    ..The "Arts" is a broad term encompassing all forms of arts including music, theater, dance, visual arts, literature, multimedia and design, folk, and traditional arts to engage the participation of all ..
  54. DiPasquale S, Becker N, Green S, Sauers K. Self-Reported Injury and Management in a Liberal Arts College Dance Department. Med Probl Perform Art. 2015;30:224-30 pubmed publisher
    ..purpose of this research was to determine the frequency and patterns of injury in a non-conservatory, liberal arts dance environment. These data may enable dance departments to provide more effective health resources...
  55. Krekula C, Arvidson M, Heikkinen S, Henriksson A, Olsson E. On gray dancing: Constructions of age-normality through choreography and temporal codes. J Aging Stud. 2017;42:38-45 pubmed publisher
    Against the background of population aging, older peoples dance has attracted attention in research and its health promoting effects and social meanings have been brought to the fore...
  56. Jago R, Edwards M, Sebire S, Tomkinson K, Bird E, Banfield K, et al. Effect and cost of an after-school dance programme on the physical activity of 11-12 year old girls: The Bristol Girls Dance Project, a school-based cluster randomised controlled trial. Int J Behav Nutr Phys Act. 2015;12:128 pubmed publisher
    The aim of this study was to examine the effectiveness and cost of an after-school dance intervention at increasing the physical activity levels of Year 7 girls (age 11-12)...
  57. Kruusamäe H, Maasalu K, Wyon M, Jurimae T, Mäestu J, Mooses M, et al. Spinal posture in different DanceSport dance styles compared with track and field athletes. Medicina (Kaunas). 2015;51:307-11 pubmed publisher
    ..1 years) volunteered. Twelve couples were Standard, 7 Latin American and 11 were Ten Dance couples...
  58. Sebire S, Edwards M, Kesten J, May T, Banfield K, Bird E, et al. Process evaluation of the Bristol girls dance project. BMC Public Health. 2016;16:349 pubmed publisher
    The Bristol Girls Dance Project was a cluster randomised controlled trial that aimed to increase objectively measured moderate-to-vigorous physical activity (MVPA) levels of Year 7 (age 11-12) girls through a dance-based after-school ..
  59. Bonny J, Lindberg J, Pacampara M. Hip Hop Dance Experience Linked to Sociocognitive Ability. PLoS ONE. 2017;12:e0169947 pubmed publisher
    Expertise within gaming (e.g., chess, video games) and kinesthetic (e.g., sports, classical dance) activities has been found to be linked with specific cognitive skills...
  60. Kotler D, Lynch M, Cushman D, Hu J, Garner J. Dancers' Perceived and Actual Knowledge of Anatomy. J Dance Med Sci. 2017;21:76-81 pubmed publisher
    ..Questions included demographic information, dance techniques studied, anatomy training, and injury history...
  61. Kobayashi M, Hanai R. M phase-specific association of human topoisomerase IIIbeta with chromosomes. Biochem Biophys Res Commun. 2001;287:282-7 pubmed
    ..The GFP fusion of the isoform 2 was found in the cytoplasm, indicating the nuclear localization signal sequence in the isoform 1 is in the C-terminal part that is different between the two isoforms. ..
  62. Hirai Y, Muragaki Y, Itoh S, Oikawa K, Juri M, Kondo T, et al. Fibulin-5 protein is reduced in the lung of patients with spontaneous pneumothorax who are under 25 years old. Ann Thorac Cardiovasc Surg. 2012;18:200-5 pubmed
    ..006), with no significant differences between groups O and C (p = 0.14). We showed that fibulin-5 is reduced in patients with PSP who are younger than 25 years. ..
  63. Lukach A, Jedrziewski M, Grove G, Mechanic Hamilton D, Williams S, Wollam M, et al. Rhythm experience and Africana culture trial (REACT!): A culturally salient intervention to promote neurocognitive health, mood, and well-being in older African Americans. Contemp Clin Trials. 2016;48:41-5 pubmed publisher
    ..is a multi-site randomized controlled intervention study designed to examine the efficacy of using African Dance as a form of moderate-intensity physical activity to improve cognitive function in older African Americans...
  64. Chan W, Ismail H, Mayaki D, Sanchez V, Tiedemann K, Davis E, et al. Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells. PLoS ONE. 2016;11:e0156994 pubmed publisher
  65. Mao Q, Lavalou J, Lecuit T. Fat2 and Lar Dance a Pas de Deux during Collective Cell Migration. Dev Cell. 2017;40:425-426 pubmed publisher
    ..In this issue of Developmental Cell, Barlan et al. (2017) delineate a Fat2/Lar planar signaling pathway at the basal, motile cell-cell contacts of Drosophila egg chamber follicle cells. ..
  66. Palamar J, Salomone A, Gerace E, Di Corcia D, Vincenti M, Cleland C. Hair testing to assess both known and unknown use of drugs amongst ecstasy users in the electronic dance music scene. Int J Drug Policy. 2017;48:91-98 pubmed publisher
    Data on both known and unknown drug use in the electronic dance music (EDM) scene is important to inform prevention and harm reduction...
  67. Karpodini C, Wyon M, Comoutos N, Koutedakis Y. Leg-Length in Relation to Selected Ballet Performance Indicators. Med Probl Perform Art. 2017;32:165-169 pubmed publisher
    It is unclear whether the modern ballet body stereotype of long limbs is advantageous in dance performance...
  68. Filipa A, Barton K. Physical Therapy Rehabilitation of an Adolescent Preprofessional Dancer Following Os Trigonum Excision: A Case Report. J Orthop Sports Phys Ther. 2018;48:194-203 pubmed publisher
    ..Following excision of an os trigonum, it is important to have a gradual, progressive return-to-dance program for optimal recovery...
  69. Brown D. Gender Diversity, Sexual Orientation, and Bone Health in the Maturing Dancer. Med Probl Perform Art. 2017;32:221-226 pubmed publisher
    ..This review seeks to underscore physiological phenomena relevant to trans-individuals, particularly in adolescents maturing into young adults, and disseminate this knowledge to dance, health, and education professionals.
  70. Kapsetaki M, Easmon C. Eating Disorders in Non-Dance Performing Artists: A Systematic Literature Review. Med Probl Perform Art. 2017;32:227-234 pubmed publisher
    ..a large impact of eating disorders (EDs) on these individuals, but there is limited research on EDs affecting non-dance performing artists (i.e., musicians, actors, etc.)...
  71. Auer Grumbach M, Weger M, Fink Puches R, Papić L, Fröhlich E, Auer Grumbach P, et al. Fibulin-5 mutations link inherited neuropathies, age-related macular degeneration and hyperelastic skin. Brain. 2011;134:1839-52 pubmed publisher
    ..Furthermore, it adumbrates a new syndrome by linking concurrent pathologic alterations affecting peripheral nerves, eyes and skin to mutations in the fibulin-5 gene. ..
  72. Subramanian I. Complementary and Alternative Medicine and Exercise in Nonmotor Symptoms of Parkinson's Disease. Int Rev Neurobiol. 2017;134:1163-1188 pubmed publisher
    ..Taichi, Qigong, dance, yoga, mindfulness, acupuncture, and other CAM therapies are reviewed and there is some evidence for the following:..
  73. Fu J, Zheng M, Zhang X, Zhang Y, Chen Y, Li H, et al. Fibulin-5 promotes airway smooth muscle cell proliferation and migration via modulating Hippo-YAP/TAZ pathway. Biochem Biophys Res Commun. 2017;493:985-991 pubmed publisher
    ..It may function at least partly through binding to ?1 integrin and modulating Hippo-YAP/TAZ pathway to promote the proliferation and migration of ASMCs. ..
  74. Li B, Zhang Q, Lin X, Chen L, Ouyang L, Zhang S. [Expression and significance of elastin and fibulin-5 in anterior vaginal tissue of women with pelvic organ prolapse]. Zhonghua Fu Chan Ke Za Zhi. 2009;44:514-7 pubmed
    ..031). The decreased expression of elastin and fibulin-5 was correlated with degree of POP, which indicated that elastin and fibulin-5 may play a role in the pathogenesis of POP. ..
  75. Okkelman I, Sukaeva A, Kirukhina E, Korneenko T, Pestov N. Nuclear translocation of lysyl oxidase is promoted by interaction with transcription repressor p66β. Cell Tissue Res. 2014;358:481-9 pubmed publisher
    ..Moreover, co-expression of p66β and LOX in living tumor cells leads to the nuclear accumulation of LOX. Thus, p66β might be important for the regulation of LOX in the nucleus. ..
  76. Zafar M, Bozzorg A, Hackney M. Adapted Tango improves aspects of participation in older adults versus individuals with Parkinson's disease. Disabil Rehabil. 2017;39:2294-2301 pubmed publisher
    ..to determine (1) the impact of aging versus combined aging and disease on participation and (2) participation before and after a 12-week, Adapted Tango dance intervention (AT) in older adults with and without Parkinson's disease (PD).
  77. Milsten A, Tennyson J, Weisberg S. Retrospective Analysis of Mosh-Pit-Related Injuries. Prehosp Disaster Med. 2017;32:636-641 pubmed publisher
    Moshing is a violent form of dancing found world-wide at rock concerts, festivals, and electronic dance music events. It involves crowd surfing, shoving, and moving in a circular rotation...
  78. Devadas U, Hegde M, Maruthy S. Prevalence and Risk Factors of Self-reported Voice Problems Among Yakshagana Artists. J Voice. 2019;33:124.e35-124.e47 pubmed publisher
    Yakshagana /jakʃaga:na/ is a form of folk theater of India. It is a blend of music, acting, dance, costume, dialogue, and stage techniques with an exclusive style and form...
  79. Miege P. May I have the next dance? Chinese gay men exploring selves and practices through the tradition of dance in public spaces. Cult Health Sex. 2017;:1-13 pubmed publisher
    This study explores the way in which some Chinese gay men negotiate dance performances in parks and other public spaces in an attempt to invent and experiment with 'possible selves'...
  80. Orriols M, Varona S, Aguiló S, Galán M, Martinez Gonzalez J, Rodriguez C. [Inflammation inhibits vascular fibulin-5 expression: Involvement of transcription factor SOX9]. Clin Investig Arterioscler. 2016;28:271-280 pubmed publisher
    Fibulin-5 (FBLN5) is an elastogenic protein critically involved in extracellular matrix (ECM) remodelling, a key process in abdominal aortic aneurysm (AAA)...
  81. ENNIS C. Educating Students for a Lifetime of Physical Activity: Enhancing Mindfulness, Motivation, and Meaning. Res Q Exerc Sport. 2017;88:241-250 pubmed publisher
    ..Using sport, physical activity, dance, and adventure activities as the means to an end for personal and social growth, we can meet our commitment to ..
  82. Angel P, Narmoneva D, Sewell Loftin M, Munjal C, Dupuis L, Landis B, et al. Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. Ann Biomed Eng. 2017;45:2548-2562 pubmed publisher
    ..matrix (ECM) proteins interacting with TGFB1, including latent transforming growth factor beta 3 (LTBP3), fibulin 5 (FBLN5), and cartilage intermediate layer protein 1 (CILP1)...
  83. Brokaw C. The Dance of "Old" and "New" in Chinese Print Culture, 1860s-1955. Sci Context. 2017;30:281-324 pubmed publisher
    ..Second, from a perspective from the top, I consider the deliberate choices made by the government, some elite book collector-publishers, and Daoist and Buddhist devotees to print certain works xylographically. ..
  84. Wang X, LeMaire S, Chen L, Carter S, Shen Y, Gan Y, et al. Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection. Surgery. 2005;138:352-9 pubmed
    ..Patients with proximal aortic dissection exhibited significantly decreased expression of aortic fibulin-5. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. ..
  85. Sideek M, Menz C, Parsi M, Gibson M. LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis. Matrix Biol. 2014;34:114-23 pubmed publisher
    ..Overall the results indicate that LTBP-2 may have a negative regulatory role during elastic fiber assembly, perhaps in displacing elastin microassemblies from complexes with fibulin-5 and/or cell surface heparan sulfate proteoglycans. ..
  86. Remy L, Buttram M, Kurtz S, Surratt H, Pechansky F. Motivations for Selling Ecstasy among Young Adults in the Electronic Dance Music Club Culture in Brazil. J Psychoactive Drugs. 2017;49:420-426 pubmed publisher
    This article describes data on the motivations for selling ecstasy among young adults in the electronic dance music (EDM) club culture in Brazil...
  87. Mainwaring L, Finney C. Psychological Risk Factors and Outcomes of Dance Injury: A Systematic Review. J Dance Med Sci. 2017;21:87-96 pubmed publisher
    Historically, dance medicine and science has focused on the physical aspects rather than the psychological aspects of dance injury...
  88. van Seters C, van Rijn R, van Middelkoop M, Stubbe J. Risk Factors for Lower-Extremity Injuries Among Contemporary Dance Students. Clin J Sport Med. 2017;: pubmed publisher
    ..To determine whether student characteristics, lower-extremity kinematics, and strength are risk factors for sustaining lower-extremity injuries in preprofessional contemporary dancers...
  89. Elahi E, Kalhor R, Banihosseini S, Torabi N, Pour Jafari H, Houshmand M, et al. Homozygous missense mutation in fibulin-5 in an Iranian autosomal recessive cutis laxa pedigree and associated haplotype. J Invest Dermatol. 2006;126:1506-9 pubmed
    ..A haplotype consisting of seven intragenic sequence variations common to both pedigrees is described for the mutation-carrying fibulin-5 allele. ..
  90. Chen X, Song X, Yue W, Chen D, Yu J, Yao Z, et al. Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer. Oncotarget. 2015;6:15022-34 pubmed
    ..Together, our results suggest that fibulin-5 functions as a metastasis suppressor in lung cancer by modulating tumor microenvironment to suppress Wnt/β-catenin signaling. ..
  91. Ai H, Kai K, Kumaraswamy A, Ikeno H, Wachtler T. Interneurons in the Honeybee Primary Auditory Center Responding to Waggle Dance-Like Vibration Pulses. J Neurosci. 2017;37:10624-10635 pubmed publisher
    Female honeybees use the "waggle dance" to communicate the location of nectar sources to their hive mates. Distance information is encoded in the duration of the waggle phase (von Frisch, 1967)...
  92. Rice P, Van Werkhoven H, Dejournette D, Gurchiek R, Mackall J, McBride J. A Comparison of Musculo-Articular Stiffness and Maximal Isometric Plantar Flexion and Knee Extension Force in Dancers and Untrained Individuals. J Dance Med Sci. 2017;21:144-150 pubmed publisher
    b>Dance involves a high volume of aesthetic, stretch-shortening cycle (SSC) actions, which may cause unique adaptations to performance. The strength dancers possess to withstand such frequency of SSCs remains elusive...