ELSPBP1

Summary

Gene Symbol: ELSPBP1
Description: epididymal sperm binding protein 1
Alias: E12, EDDM12, EL149, HE12, epididymal sperm-binding protein 1, epididymal protein 12, epididymal secretory protein 12, epididymis luminal secretory protein 149
Species: human
Products:     ELSPBP1

Top Publications

  1. Wu Y, Reece E, Zhong J, Dong D, Shen W, Harman C, et al. Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis. Am J Obstet Gynecol. 2016;215:366.e1-366.e10 pubmed publisher
    ..At E12.5, embryonic hearts were harvested to determine the levels of lipid peroxides and superoxide, endoplasmic reticulum ..
  2. Kasimanickam R, Kasimanickam V, Arangasamy A, Kastelic J. Sperm and seminal plasma proteomics of high- versus low-fertility Holstein bulls. Theriogenology. 2019;126:41-48 pubmed publisher
    ..05), whereas proteins CLU, CCT5 and 8, ELSPbP1, and PSMA6 were more abundant in sperm and seminal plasma of low- versus high-fertility bulls (P < 0.05)...
  3. Na W, Wu Y, Gong P, Wu C, Cheng B, Wang Y, et al. Embryonic transcriptome and proteome analyses on hepatic lipid metabolism in chickens divergently selected for abdominal fat content. BMC Genomics. 2018;19:384 pubmed publisher
    ..We performed transcriptome and proteome profiling on chicken livers at five embryonic stages (E7, E12, E14, E17 and E21) between the fat and lean chicken lines...
  4. Yanjiang X, Hongjuan H, Tiantian G, Yan Z, Zhijun H, Qiong W. Expression patterns of ubiquitin conjugating enzyme UbcM2 during mouse embryonic development. Gene Expr. 2012;15:163-70 pubmed
    ..During brain development, the expression level of UbcM2 first ascended and then decreased from E12.5 to E18.5, the peak of which sustained starting at E14.5 until E16.5...
  5. Buniello A, Hardisty Hughes R, Pass J, Bober E, Smith R, Steel K. Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS ONE. 2013;8:e56274 pubmed publisher
    ..We use Trp2 as a marker of melanoblasts migrating from the neural crest at E12.5 and show that they do not interdigitate into the developing strial epithelium, associated with abnormal ..
  6. Bosch P, Fuller L, Sleeth C, Weiner J. Akirin2 is essential for the formation of the cerebral cortex. Neural Dev. 2016;11:21 pubmed
    ..All of the neurons that are generated in Akirin2 mutants also undergo apoptosis by E12. In situ hybridization for Wnt3a and Wnt-responsive genes suggest defective formation and/or function of the ..
  7. Baumgartner M, Lemoine C, Al Seesi S, Karunakaran D, Sturrock N, Banday A, et al. Minor splicing snRNAs are enriched in the developing mouse CNS and are crucial for survival of differentiating retinal neurons. Dev Neurobiol. 2015;75:895-907 pubmed publisher
    ..5 and E12.5, along with enrichment of these snRNAs in differentiating retinal neurons...
  8. Zhang B, Chang J, Fu M, Huang J, Kashyap R, Salavaggione E, et al. Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. PLoS ONE. 2009;4:e5232 pubmed publisher
    ..While Pds5A(-/-) and Pds5B(-/-) mice die at birth, embryos harboring 3 mutant Pds5 alleles die between E11.5 and E12.5 most likely of heart failure, indicating that total Pds5 gene dosage is critical for normal development...
  9. Torii H, Yoshida A, Katsuno T, Nakagawa T, Ito J, Omori K, et al. Septin7 regulates inner ear formation at an early developmental stage. Dev Biol. 2016;419:217-228 pubmed publisher
    ..Excessive apoptosis was observed at E10.5,E11.5 and E12.5 in all inner ear epithelial cells and at E10.5 and E11...

More Information

Publications140 found, 100 shown here

  1. Blanco M, Rodriguez Martin I, Learte A, Clemente C, Montalvo M, Seiki M, et al. Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo. PLoS ONE. 2017;12:e0184767 pubmed publisher
    ..A strong expression in the brain begins at E12.5 and continues to postnatal stages...
  2. Wang C, Li H, Luo C, Li Y, Zhang Y, Yun D, et al. The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure. Placenta. 2015;36:1138-47 pubmed publisher
    ..Compared with control group at the same gestational day (E12.5, E15.5, E17...
  3. D Amours O, Frenette G, Bourassa S, Calvo É, Blondin P, Sullivan R. Proteomic Markers of Functional Sperm Population in Bovines: Comparison of Low- and High-Density Spermatozoa Following Cryopreservation. J Proteome Res. 2018;17:177-188 pubmed publisher
    ..iTRAQ analysis revealed that other proteins such as binder of sperm proteins, histone, GPX5, ELSPBP1, and clusterin are overexpressed in low-density spermatozoa suggesting that these proteins represent defects ..
  4. Amodeo D, Lai C, Hassan O, Mukamel E, Behrens M, Powell S. Maternal immune activation impairs cognitive flexibility and alters transcription in frontal cortex. Neurobiol Dis. 2019;125:211-218 pubmed publisher
    ..Poly(I:C) (20 mg/kg) was administered to dams on E12.5 and offspring were tested for social approach behavior, repetitive grooming, and probabilistic reversal learning ..
  5. Wang C, Zhang Y, Zhan Y, Luo C, Li Y, Qiu D, et al. The effect of 17α-ethynylestradiol induced intrahepatic cholestasis of pregnancy on placental P-glycoprotein in mice: Implications in the individualized transplacental digoxin treatment for fetal heart failure. Placenta. 2016;44:91-7 pubmed publisher
    ..mice was induced by subcutaneous injection of 17α-ethynylestradiol dissolved in propylene glycol once daily from E12.5 to E16.5. Maternal plasma ALT, AST, TB, DBIL, γ-GT, LDH, ALP and TBA concentrations were measured...
  6. Kawata M, Taniguchi Y, Mori D, Yano F, Ohba S, Chung U, et al. Different regulation of limb development by p63 transcript variants. PLoS ONE. 2017;12:e0174122 pubmed publisher
    ..Here, we quantified the expression of p63 variants in mouse limbs from embryonic day (E) 10.5 to E12.5, and found that ?Np63? was strongly expressed in limbs at all stages, while TAp63? expression was rapidly ..
  7. Valentine G, Seferovic M, Fowler S, Major A, Gorchakov R, Berry R, et al. Timing of gestational exposure to Zika virus is associated with postnatal growth restriction in a murine model. Am J Obstet Gynecol. 2018;219:403.e1-403.e9 pubmed publisher
    ..Our low rate of infection and relatively rare evidence of congenital Zika syndrome parallels human population-based data. ..
  8. CONSTANZO J, Deng M, Rindhe S, Tang K, Zhang C, Scaglioni P. Pias1 is essential for erythroid and vascular development in the mouse embryo. Dev Biol. 2016;415:98-110 pubmed publisher
    ..Approximately 90% of Pias1 null embryos die in utero between E10.5 and E12.5...
  9. Gluckman T, Mundy N. The differential expression of MC1R regulators in dorsal and ventral quail plumages during embryogenesis: Implications for plumage pattern formation. PLoS ONE. 2017;12:e0174714 pubmed publisher
    ..Melanocytes are present in all feather follicles at both 8 and 12 days post-fertilisation (E8/E12), so differential deposition of melanocytes is not responsible for pigmentation patterns in embryonic quail...
  10. Wu D, Mandal S, Choi A, Anderson A, Prochazkova M, Perry H, et al. DLX4 is associated with orofacial clefting and abnormal jaw development. Hum Mol Genet. 2015;24:4340-52 pubmed publisher
    ..In situ hybridization showed that Dlx4 was expressed in the mesenchyme of the murine palatal shelves at E12.5, prior to palate closure. Wild-type human DLX4, but not mutant DLX4_c...
  11. Joselit Y, Nanobashvili K, Jack Roberts C, Greenwald E, Malysheva O, Caudill M, et al. Maternal betaine supplementation affects fetal growth and lipid metabolism of high-fat fed mice in a temporal-specific manner. Nutr Diabetes. 2018;8:41 pubmed publisher
    ..Maternal, placental, and fetal samples were collected for metabolite and gene-expression assays. At E12.5, BS prevented fetal and placental overgrowth and downregulated glucose and fatty acid transporters (Glut1 and ..
  12. Fjodorova M, Torres E, Dunnett S. Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats. Exp Neurol. 2017;291:8-19 pubmed publisher
    ..We demonstrate that young (embryonic day, E12), but not older (E14), mesencephalic tissue and the transplant environment influence survival and functional ..
  13. Tsuda T, Iwai N, Deguchi E, Kimura O, Ono S, Furukawa T, et al. PCSK5 and GDF11 expression in the hindgut region of mouse embryos with anorectal malformations. Eur J Pediatr Surg. 2011;21:238-41 pubmed publisher
    ..0. Embryos were harvested between days E12 and E18, and mid-sagittal sections of the hindgut region were prepared for immunohistochemistry using antibodies ..
  14. Yeung C, Taylor S, Garva R, Holmes D, Zeef L, Soininen R, et al. Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibers. PLoS ONE. 2014;9:e107036 pubmed publisher
    ..We generated an Arhgap28-LacZ reporter mouse that revealed gene expression in soft tissues at E12.5, pre-bone structures of the limb at E15...
  15. Kossler N, Stricker S, Rödelsperger C, Robinson P, Kim J, Dietrich C, et al. Neurofibromin (Nf1) is required for skeletal muscle development. Hum Mol Genet. 2011;20:2697-709 pubmed publisher
    ..This was caused by an early defect in myogenesis affecting the terminal differentiation of myoblasts between E12.5 and E14.5. In parallel, the muscle connective tissue cells exhibited increased proliferation at E14...
  16. Giacomini E, Ura B, Giolo E, Luppi S, Martinelli M, Garcia R, et al. Comparative analysis of the seminal plasma proteomes of oligoasthenozoospermic and normozoospermic men. Reprod Biomed Online. 2015;30:522-31 pubmed publisher
  17. Chumak T, Bohuslavova R, Macova I, Dodd N, Buckiova D, Fritzsch B, et al. Deterioration of the Medial Olivocochlear Efferent System Accelerates Age-Related Hearing Loss in Pax2-Isl1 Transgenic Mice. Mol Neurobiol. 2016;53:2368-83 pubmed publisher
    ..increases the embryonic ISL1(+) domain and induces accelerated nerve fiber extension and branching in E12.5 embryos...
  18. Tian Q, Smart J, Clement J, Wang Y, Derkatch A, Schubert H, et al. RHEB1 expression in embryonic and postnatal mouse. Histochem Cell Biol. 2016;145:561-72 pubmed publisher
    ..5 and postimplantation embryos up to E12.5. Between stages E13.5 and E16...
  19. Alić I, Kosi N, Kapuralin K, Gorup D, Gajovic S, Pochet R, et al. Neural stem cells from mouse strain Thy1 YFP-16 are a valuable tool to monitor and evaluate neuronal differentiation and morphology. Neurosci Lett. 2016;634:32-41 pubmed publisher
    ..During embryonic development Thy1-YFP positive cells were first observed on E12.5 and subsequently located in the prosencephalon, rhombencephalon, spinal cord and peripheral nerves...
  20. Bojanic D, Tarr P, Gale G, Smith D, Bok D, Chen B, et al. Differential expression and function of ABCG1 and ABCG4 during development and aging. J Lipid Res. 2010;51:169-81 pubmed publisher
    ..We also show that ABCG1 and ABCG4 are both expressed as early as E12.5 in the embryonic eye and developing CNS...
  21. Limi S, Senecal A, Coleman R, Lopez Jones M, Guo P, Polumbo C, et al. Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. J Biol Chem. 2018;293:13176-13190 pubmed publisher
    ..and γ-crystallin genes by RNA fluorescent in situ hybridization (FISH) in the lenses of embryonic day (E) E12.5, E14.5, and E16.5 mouse embryos and newborns...
  22. Wang B, Balakrishnan Renuka A, Napirei M, Theiss C, Brand Saberi B. Spatiotemporal expression of Math6 during mouse embryonic development. Histochem Cell Biol. 2015;143:575-82 pubmed publisher
    ..At stages E11.5 and E12.5, Math6 transcripts were accumulated in the developing brain, heart, limb buds and liver...
  23. Acquaye Seedah E, Reczek E, Russell H, DiVenere A, Sandman S, Collins J, et al. Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization. Infect Immun. 2018;86: pubmed publisher
    ..comprehensive mutagenesis with yeast display provided a detailed map of the epitope recognized by antibodies A8 and E12. Residue R76 is required for antibody A8 binding and is present on the S1 surface but is only partially exposed in ..
  24. Rumpel R, Hohmann M, Klein A, Wesemann M, Baumgärtner W, Ratzka A, et al. Transplantation of fetal ventral mesencephalic progenitor cells overexpressing high molecular weight fibroblast growth factor 2 isoforms in 6-hydroxydopamine lesioned rats. Neuroscience. 2015;286:293-307 pubmed publisher
    ..the high molecular weight (HMW) isoform, which, after non-viral plasmid-based overexpression in embryonic day 12 (E12) rat ventral mesencephalon (VM)-derived cells, revealed increased numbers of tyrosine hydroxylase-positive (TH(+)) ..
  25. Rakoczy J, Padmanabhan N, Krzak A, Kieckbusch J, Cindrova Davies T, Watson E. Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation. Placenta. 2017;59:46-56 pubmed publisher
    ..In mouse, Tet1-3 mRNA was widely expressed in trophoblast cell populations from embryonic (E) day 8.5 to E12.5 including in progenitor and differentiated cells...
  26. Reteno D, Benamar S, Khalil J, Andreani J, Armstrong N, Klose T, et al. Faustovirus, an asfarvirus-related new lineage of giant viruses infecting amoebae. J Virol. 2015;89:6585-94 pubmed
    ..This new lineage was proposed to be the faustovirus lineage. The prototype member, faustovirus E12, forms icosahedral virions of ≈ 200 nm that are devoid of fibrils and that encapsidate a 466-kbp genome ..
  27. Dai J, Yu D, Wang Y, Chen Y, Sun H, Zhang X, et al. Kdm6b regulates cartilage development and homeostasis through anabolic metabolism. Ann Rheum Dis. 2017;76:1295-1303 pubmed publisher
    ..5 and E18.5 with intraperitoneal injection of tamoxifen at E12.5...
  28. Cuffe J, Saif Z, Perkins A, Moritz K, Clifton V. Dexamethasone and sex regulate placental glucocorticoid receptor isoforms in mice. J Endocrinol. 2017;234:89-100 pubmed publisher
    ..Pregnant C57Bl6 mice were exposed to saline or dexamethasone from E12.5 until E14.5 (1?µg/kg/h) before the collection of placentae...
  29. Tenin G, Clowes C, Wolton K, Krejci E, Wright J, Lovell S, et al. Erbb2 is required for cardiac atrial electrical activity during development. PLoS ONE. 2014;9:e107041 pubmed publisher
    ..Homozygous mutant embryos exhibit embryonic lethality by E12.5-13...
  30. Spanic T, Fabjan T, Majdic G. Expression levels of mRNA for neurosteroidogenic enzymes 17β-HSD, 5α-reductase, 3α-HSD and cytochrome P450 aromatase in the fetal wild type and SF-1 knockout mouse brain. Endocr Res. 2015;40:44-8 pubmed publisher
    ..Brains were collected from WT and SF-1 knockout male and female fetuses at embryonic (E) days E12, E14, E16, and E18...
  31. Zhang P, Xu Y, Zhu X, Huang Y. Goblet cell targeting nanoparticle containing drug-loaded micelle cores for oral delivery of insulin. Int J Pharm. 2015;496:993-1005 pubmed publisher
    ..For in vitro evaluation, Caco-2/HT29-MTX-E12 cell co-cultures, which composed of not only enterocyte-like cells but also mucus-secreting cells and secreted ..
  32. Falodah F, Al Karim S. Immuno- and gene expression analysis of EGFR and Nestin during mice skin development. Tissue Cell. 2016;48:274-81 pubmed publisher
    ..In this comparative cross sectional study, six ages been chosen and divided into: embryonic days (E12.5, E14.5 and E19.5) and litter days (L7, L14 and L19)...
  33. Shibuya M, Ikari T, Sugiyama G, Ohyama Y, Kumamaru W, Nagano K, et al. Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands. Differentiation. 2016;92:216-224 pubmed publisher
    ..We investigated the expression of all FGFR family members in fetal SGs between embryonic day 12.5 (E12.5) and E18.5...
  34. Watanabe M, Kawasaki K, Kawasaki M, Portaveetus T, Oommen S, Blackburn J, et al. Spatio-temporal expression of Sox genes in murine palatogenesis. Gene Expr Patterns. 2016;21:111-8 pubmed publisher
    ..At palatal shelf initiation (E12.5), the localized expression of six Sox genes (Sox2, 5, 6, 9, 12 and 13) was observed in the shelves, whereas Sox4 ..
  35. Li J, Dai H, Feng Y, Tang J, Chen S, Tian X, et al. A Comprehensive Strategy for Accurate Mutation Detection of the Highly Homologous PMS2. J Mol Diagn. 2015;17:545-53 pubmed publisher
    ..Exonic deletions (E2 to E9, E5 to E9, E8, E10, E14, and E1 to E15), duplications (E11 to E12), and a nonsense mutation, p.S22*, were identified...
  36. Barik A, Li L, Sathyamurthy A, Xiong W, Mei L. Schwann Cells in Neuromuscular Junction Formation and Maintenance. J Neurosci. 2016;36:9770-81 pubmed publisher
    ..5, suggesting that SCs may not be necessary for aneural clusters. SC ablation at E12.5, a time when phrenic nerves approach muscle fibers, resulted in smaller and fewer nerve-induced AChR clusters; ..
  37. Langlands K, Yin X, Anand G, Prochownik E. Differential interactions of Id proteins with basic-helix-loop-helix transcription factors. J Biol Chem. 1997;272:19785-93 pubmed
    Dimerization of three Id proteins (Id1, Id2, and Id3) with the four class A E proteins (E12, E47, E2-2, and HEB) and two groups of class B proteins, the myogenic regulatory factors (MRFs: MyoD, myogenin, Myf-5 and MRF4/Myf-6), and the ..
  38. Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, et al. CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion. Mucosal Immunol. 2017;10:1145-1159 pubmed publisher
    ..5 (E12.5) and are similar to yolk sac-derived macrophages, microglia, in phenotype and gene expression, and CCR2+
  39. Murata H, Sunohara M, Sato I. Expression of DMP1 in the developing mouse tongue embryo. Ann Anat. 2015;200:136-48 pubmed publisher
    ..5 (E12.5), E14.5, E17.5, and E18.5...
  40. Maeda Y, Miwa Y, Sato I. Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia. Eur J Histochem. 2017;61:2750 pubmed publisher
    ..5 (E12.5), E14.5, E17.5, and postnatal day 1 (P1). CGRP was clearly detected in the mandible relative to the tibia at E14...
  41. Birch D, Diedrichsen R, Christophersen P, Mu H, Nielsen H. Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium. Eur J Pharm Sci. 2018;118:144-153 pubmed publisher
    ..was compared to that of cell monolayers without BM and well-established mucus-secreting epithelial models (HT29-MTX-E12 cell monolayers and HT29-MTX-E12/Caco-2 cell co-culture monolayers)...
  42. Chang H, Smallwood P, Williams J, Nathans J. The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation. Dev Biol. 2016;409:181-193 pubmed publisher
    ..Fz6 is required starting between embryonic day (E)11.5 and E12.5...
  43. Uehara T, Kitahara H, Naka H, Matsuyama S, Ando T, Honda H. Single-Component Pheromone Consisting of Bombykal in a Diurnal Hawk Moth, Neogurelca himachala sangaica. J Chem Ecol. 2016;42:517-22 pubmed publisher
    ..on two GC columns as (10E,12Z)-10,12-hexadecadienal (E10,Z12-16:Ald) and a trace of its (10E,12E)-isomer (E10,E12-16:Ald) in 98:2 ratio...
  44. Gumusoglu S, Fine R, Murray S, Bittle J, Stevens H. The role of IL-6 in neurodevelopment after prenatal stress. Brain Behav Immun. 2017;65:274-283 pubmed publisher
    ..after repetitive maternal restraint stress, repetitive maternal IL-6, or maternal IL-6 blockade during stress from E12 onwards...
  45. Hashimoto H, Jiang W, Yoshimura T, Moon K, Bok J, Ikenaka K. Strong sonic hedgehog signaling in the mouse ventral spinal cord is not required for oligodendrocyte precursor cell (OPC) generation but is necessary for correct timing of its generation. Neurochem Int. 2018;119:178-183 pubmed publisher
    ..Thus, Shh signaling input to the pMN domain at E12.5 was reduced in bromi mutant mice...
  46. Okello D, Iyyanar P, Kulyk W, Smith T, Lozanoff S, Ji S, et al. Six2 Plays an Intrinsic Role in Regulating Proliferation of Mesenchymal Cells in the Developing Palate. Front Physiol. 2017;8:955 pubmed publisher
    ..that Six2 mRNA and protein levels were upregulated in Hoxa2-/- palatal shelves at stages E12.5-14.5...
  47. Giromini C, Baldi A, Fusi E, Rebucci R, Purup S. Effect of growth factors, estradiol 17-β, and short chain fatty acids on the intestinal HT29-MTX cells : Growth factors and SCFAs effects on intestinal E12 cells. Cell Biol Toxicol. 2015;31:199-209 pubmed publisher
    ..factors, estradiol 17-β, and SCFAs on the metabolic activity and proliferation of undifferentiated HT29-MTX-E12 (E12) cells...
  48. Nishimura W, Kapoor A, El Khattabi I, Jin W, Yasuda K, Bonner Weir S, et al. Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors. PLoS ONE. 2015;10:e0142286 pubmed publisher
    ..5. Induction of the transgene only until E12.5 in Pdx1+ 1°MPC was sufficient for this inhibition of endocrine cells and pancreatic mass at E17.5...
  49. Bhat N, Park J, Zoghbi H, Arthur J, Zaret K. The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development. PLoS ONE. 2016;11:e0166703 pubmed publisher
    ..H3S28ph and MSK1/2 were enriched at the key endocrine and acinar promoters in E12.5 multipotent pancreatic progenitors...
  50. Ma L, Shi B, Zheng Q. Cell Polarity and PAR Complex Likely to Be Involved in Dexamethasone-Induced Cleft Palate. J Craniofac Surg. 2017;: pubmed publisher
    ..9% sodium chloride 0.1?mL, which contained DEX 6?mg/kg respectively, every day from E10 to E12. The palatal epithelia morphology was observed with hematoxylin and eosin and scanning electron microscopy...
  51. Grignon D, Ro J, Ordonez N, Ayala A, Cleary K. Basal cell hyperplasia, adenoid basal cell tumor, and adenoid cystic carcinoma of the prostate gland: an immunohistochemical study. Hum Pathol. 1988;19:1425-33 pubmed
    ..Monoclonal antibodies (MoAb) directed against a cytokeratin, which selectively stains basal cells (34 beta E12), and against muscle-specific actin, which stains myoepithelial cells (HHF35), were used...
  52. Bouard C, Terreux R, Honorat M, Manship B, Ansieau S, Vigneron A, et al. Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences. Nucleic Acids Res. 2016;44:5470-89 pubmed publisher
    ..Here, we used an in silico model of the TWIST1/E12 (TE) heterocomplex and performed molecular dynamics (MD) simulations of its binding to specific (TE-box) and ..
  53. Koshida R, Oishi H, Hamada M, Takei Y, Takahashi S. MafB is required for development of the hindbrain choroid plexus. Biochem Biophys Res Commun. 2017;483:288-293 pubmed publisher
    ..Furthermore, the Mafb-deficient hChP exhibits increased apoptotic cell death and decreased proliferating cells at E12.5, an early stage of hChP development...
  54. Boakye P, Schmidt E, Rancic V, Kerr B, Ballanyi K, Smith P. Characterization of Superficial Dorsal Horn Neurons from "Tamamaki" Mice and Stability of their GAD67-EGFP Phenotype in Defined-Medium Organotypic Culture. Neuroscience. 2018;372:126-140 pubmed publisher
    ..All seven phenotypes were preserved in mouse spinal cord neurons in DMOTC prepared from e12 embryos and the GAD67-EGFP+ phenotype continued to associate with phasic and regular firing neurons...
  55. Boles M, Wilkinson B, Maxwell A, Lai L, Mills A, Nishijima I, et al. A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009;10:12 pubmed publisher
    ..The majority of lines die during embryonic development between E5.5 and E12.5 and display defects in gastrulation, cardiac development, and craniofacial development...
  56. Furumatsu T, Shukunami C, Amemiya Kudo M, Shimano H, Ozaki T. Scleraxis and E47 cooperatively regulate the Sox9-dependent transcription. Int J Biochem Cell Biol. 2010;42:148-56 pubmed publisher
    ..These findings suggest that Scx and E47 might modulate the primary chondrogenesis by associating with the Sox9-related transcriptional complex, and by binding to the conserved E-box on Col2a1 promoter. ..
  57. Banerjee P, Harada H, Tassew N, Charish J, Goldschneider D, Wallace V, et al. Ï’-secretase and LARG mediate distinct RGMa activities to control appropriate layer targeting within the optic tectum. Cell Death Differ. 2016;23:442-53 pubmed publisher
    ..In younger embryos (E12), C-RGMa and LARG-PDZ prevented ectopic projections toward deeper tectal layers, indicating that C-RGMa may act as ..
  58. Hanssens S, Marx Deseure A, Lecoutre S, Butruille L, Fournel A, Knauf C, et al. Maternal obesity alters the apelinergic system at the feto-maternal interface. Placenta. 2016;39:41-4 pubmed publisher
    ..Ex-vivo, the placenta releases apelin at E12.5 and E18.5...
  59. Li A, Davis J, Wierwille J, Herold K, Morgan D, Behr E, et al. Relationship Between Distance and Change in Surface ECG Morphology During Pacemapping as a Guide to Ablation of Ventricular Arrhythmias: Implications for the Spatial Resolution of Pacemapping. Circ Arrhythm Electrophysiol. 2017;10: pubmed publisher
    ..of distance against morphology difference measured by the root mean square error sum across all 12 ECG leads (E12). Forty of 68 (58%) patients had structural heart disease, and 21/40 (53%) patients were ischemic...
  60. Kumar A, Thakur M. Binding of transcription factors to Presenilin 1 and 2 promoter cis-acting elements varies during the development of mouse cerebral cortex. Neurosci Lett. 2016;628:98-104 pubmed publisher
    ..For PS2 promoter, the binding of Nkx2.2 and HFH-2 was high at prenatal stages (E12.5 and E18.5) while that of Cdx1 and NF-κB was maximum at postnatal stages (P45 and 20w)...
  61. Kang H, Takeda Y, Jeon K, Jetten A. The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells. PLoS ONE. 2016;11:e0157138 pubmed publisher
    ..Immunohistochemistry showed that Glis3-EGFP was not detectable during early pancreatic development (E11.5 and E12.5) and at E13.5 and 15...
  62. Kanemitsu Y, Fujitani M, Fujita Y, Zhang S, Su Y, Kawahara Y, et al. The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain. Sci Rep. 2017;7:1155 pubmed publisher
    ..Overexpression of sMARF1 in E12.5 neuronal progenitor cells promoted neuronal differentiation, whereas sMARF1 knockdown decreased neuronal ..
  63. King J, Kwan S, Yan J, Klatt K, Jiang X, Roberson M, et al. Maternal Choline Supplementation Alters Fetal Growth Patterns in a Mouse Model of Placental Insufficiency. Nutrients. 2017;9: pubmed publisher
    ..5. No differences in fetal growth parameters were detected at E12.5 and 15.5, whereas a small but significant reduction in fetal weight was detected at E18.5 in 4X versus 1X choline...
  64. Nakazawa Tanaka N, Miyahara K, Fujiwara N, Urao M, Akazawa C, Yamataka A. Three- and four-dimensional analysis of altered behavior of enteric neural crest derived cells in the Hirschsprung's disease mouse model. Pediatr Surg Int. 2016;32:3-7 pubmed publisher
    ..5 (E15.5) and Sox10-Venus(+)/Ednrb (+/+) mice on E12.5, which was used as control...
  65. Saeidi S, Shapouri F, de Iongh R, Casagranda F, Sutherland J, Western P, et al. Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis. PLoS ONE. 2018;13:e0190925 pubmed publisher
    ..in both male and female germ cells but not in gonadal somatic cells at various stages of gonadal development (E12.5-E15.5)...
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