Gene Symbol: DIP2B
Description: disco interacting protein 2 homolog B
Alias: disco-interacting protein 2 homolog B, DIP2 disco-interacting protein 2 homolog B
Xie H, Diber A, Pollock S, Nemzer S, Safer H, Meloon B, et al
. Bridging expressed sequence alignments through targeted cDNA sequencing. Genomics. 2004;83:572-6 pubmed
..Additional information about the contig pairs, the resultant overlapping sequences, tissue sources, and tissue profiles are available in a supplemental file. ..
Iuchi S, Paulo J. Lysine-specific demethylase 2A enhances binding of various nuclear factors to CpG-rich genomic DNAs by action of its CXXC-PHD domain. Sci Rep. 2019;9:5496 pubmed publisher
..In vitro, CXXC-PHD enhances binding of nuclear extract ORC3 to the CpG-rich promoter, but not to the AT-rich DIP2B promoter to which ORC3 binds constitutively...
Gong J, Qiu C, Huang D, Zhang Y, Yu S, Zeng C. Integrative functional analysis of super enhancer SNPs for coronary artery disease. J Hum Genet. 2018;63:627-638 pubmed publisher
..Interestingly, we found 7 novel functional loci (CBFA2T3, ZMIZ1, DIP2B, SCNN1D/ACAP3, TMEM105, CAMK2G, and MAPK1) that CAD-associated super enhancer SNPs were clustered into the same or ..
Winnepenninckx B, Debacker K, Ramsay J, Smeets D, Smits A, Fitzpatrick D, et al
. CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1. Am J Hum Genet. 2007;80:221-31 pubmed
..This repeat is in the 5' untranslated region of the gene DIP2B, which encodes a protein with a DMAP1-binding domain, which suggests a role in DNA methylation machinery...
Hayashi T, Lombaert I, Hauser B, Patel V, Hoffman M. Exosomal MicroRNA Transport from Salivary Mesenchyme Regulates Epithelial Progenitor Expansion during Organogenesis. Dev Cell. 2017;40:95-103 pubmed publisher
..KIT+ progenitors, and increased expression of a target gene, Disco-interacting protein 2 homolog B (Dip2b)...
Khorram O, Garthwaite M, Johnson M, Denessiouk K, Han G, Guo T, et al
. Identification and characterization of a novel luciferase-like protein in the human female reproductive tract. J Clin Endocrinol Metab. 2004;89:5837-46 pubmed
Houlston R, Cheadle J, Dobbins S, Tenesa A, Jones A, Howarth K, et al
. Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat Genet. 2010;42:973-7 pubmed publisher
..02 × 10??) and 20q13.33 (rs4925386, OR = 0.93, P = 1.89 × 10?¹?). In addition to identifying new CRC risk loci, this analysis provides evidence that additional CRC-associated variants of similar effect size remain to be discovered. ..
Whiffin N, Hosking F, Farrington S, Palles C, Dobbins S, Zgaga L, et al
. Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. Hum Mol Genet. 2014;23:4729-37 pubmed publisher
..Our findings provide further insights into the genetic and biological basis of inherited genetic susceptibility to CRC. ..
Zhao Y, He A, Zhu F, Ding M, Hao J, Fan Q, et al
. Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2018;81:50-54 pubmed publisher
..The top five significant genes were CRELD2 (p value=1.65×10-11), DIP2B (p value=3.94×10-11), ZDHHC18 (p value=1.52×10-10) and ZDHHC5 (p value=7...